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Search of human proteins with 8923421
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo
sapiens]
(518 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo sap... 1045 0.0
gi|225579074 seryl-tRNA synthetase 2 isoform a precursor [Homo s... 981 0.0
gi|16306548 seryl-tRNA synthetase [Homo sapiens] 168 1e-41
gi|21735548 centrosomal protein 2 [Homo sapiens] 35 0.13
gi|218749820 hypothetical protein LOC84221 isoform 1 [Homo sapiens] 34 0.28
gi|20070228 nucleobindin 1 [Homo sapiens] 33 0.48
gi|109715862 gem (nuclear organelle) associated protein 8 [Homo ... 33 0.48
gi|109715864 gem (nuclear organelle) associated protein 8 [Homo ... 33 0.48
gi|8923481 gem (nuclear organelle) associated protein 8 [Homo sa... 33 0.48
gi|210032790 hypothetical protein LOC27146 [Homo sapiens] 33 0.63
gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens] 33 0.82
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens] 33 0.82
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens] 33 0.82
gi|44890059 involucrin [Homo sapiens] 32 1.1
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [... 32 1.1
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [... 32 1.1
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [... 32 1.1
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 32 1.4
gi|194394141 nucleolar preribosomal-associated protein 1 [Homo s... 32 1.8
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 31 2.4
gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 31 2.4
gi|239748049 PREDICTED: similar to NADH dehydrogenase [ubiquinon... 31 3.1
gi|27477127 keratin 82 [Homo sapiens] 31 3.1
gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1... 31 3.1
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 31 3.1
gi|45439327 periplakin [Homo sapiens] 31 3.1
gi|33589848 transferrin receptor 2 [Homo sapiens] 30 4.1
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 30 4.1
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 30 4.1
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 30 4.1
>gi|8923421 seryl-tRNA synthetase 2 isoform b precursor [Homo
sapiens]
Length = 518
Score = 1045 bits (2703), Expect = 0.0
Identities = 518/518 (100%), Positives = 518/518 (100%)
Query: 1 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI 60
MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI
Sbjct: 1 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI 60
Query: 61 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL 120
ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL
Sbjct: 61 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL 120
Query: 121 LANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPV 180
LANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPV
Sbjct: 121 LANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPV 180
Query: 181 GDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQH 240
GDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQH
Sbjct: 181 GDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALLQH 240
Query: 241 GLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTA 300
GLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTA
Sbjct: 241 GLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNLAGTA 300
Query: 301 EVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPG 360
EVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPG
Sbjct: 301 EVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPG 360
Query: 361 LEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVT 420
LEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVT
Sbjct: 361 LEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVT 420
Query: 421 SASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPA 480
SASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPA
Sbjct: 421 SASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPA 480
Query: 481 LQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS 518
LQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS
Sbjct: 481 LQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS 518
>gi|225579074 seryl-tRNA synthetase 2 isoform a precursor [Homo
sapiens]
Length = 520
Score = 981 bits (2535), Expect = 0.0
Identities = 498/522 (95%), Positives = 500/522 (95%), Gaps = 6/522 (1%)
Query: 1 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI 60
MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI
Sbjct: 1 MAASMARRLWPLLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDI 60
Query: 61 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL 120
ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL
Sbjct: 61 ERFCACPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRAL 120
Query: 121 LANQDSGEVQQ---DPKYQGL-RARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHP 176
LANQDSGEVQQ DP + +L L EAQLEEQFYLQALKLPNQTHP
Sbjct: 121 LANQDSGEVQQVRLDPGAGSIFGPTFLPFPGQLSLLV--EAQLEEQFYLQALKLPNQTHP 178
Query: 177 DVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGA 236
DVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGA
Sbjct: 179 DVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGA 238
Query: 237 LLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNL 296
LLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNL
Sbjct: 239 LLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMTPNANPSQIYNIDPARFKDLNL 298
Query: 297 AGTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGV 356
AGTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGV
Sbjct: 299 AGTAEVGLAGYFMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGV 358
Query: 357 TGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRF 416
TGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRF
Sbjct: 359 TGPGLEQSSQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRF 418
Query: 417 GEVTSASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVL 476
GEVTSASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVL
Sbjct: 419 GEVTSASNCTDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQKDGSVL 478
Query: 477 VPPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS 518
VPPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS
Sbjct: 479 VPPALQSYLGTDRITAPTHVPLQYIGPNQPRKPGLPGQPAVS 520
>gi|16306548 seryl-tRNA synthetase [Homo sapiens]
Length = 514
Score = 168 bits (425), Expect = 1e-41
Identities = 101/342 (29%), Positives = 178/342 (52%), Gaps = 18/342 (5%)
Query: 158 QLEEQFYLQALKLPNQTHPDVPVGDESQA--RVLHMVGDKPVFSFQPRGHLEIGEKLDII 215
+LE + + ++ N HP VP+ ++ +V + GD V + H+++ +D
Sbjct: 123 KLEAERFENLREIGNLLHPSVPISNDEDVDNKVERIWGDCTVR--KKYSHVDLVVMVDGF 180
Query: 216 RQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFNKLLRRGFTPMTVPDLLRGAVFEGCGMT 275
++ + V+G R Y+L+G L+ L+ + L RG+ P+ P +R V +
Sbjct: 181 EGEKGAVVAGSRGYFLKGVLVFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQL 240
Query: 276 PNANPSQIYNI--------DPARFKDLNLAGTAEVGLAGYFMDHTVAFRDLPVRMVCSST 327
+ ++Y + D + + L T+E +A D + DLP++ ST
Sbjct: 241 SQFD-EELYKVIGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLST 299
Query: 328 CYRAETNT-GQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQLLEEFLSLQMEILTELGLHF 386
C+R E + G++ RG++RVH F K+E F + P +S ++ EE ++ E LG+ +
Sbjct: 300 CFRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEEFYQSLGIPY 359
Query: 387 RVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASNCTDFQSRRLHIMF-QTE--AGE 443
++++ + L A +K D+EAW PG G F E+ S SNCTD+Q+RRL I + QT+ +
Sbjct: 360 HIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTDYQARRLRIRYGQTKKMMDK 419
Query: 444 LQFAHTVNATACAVPRLLIALLESNQQKDGSVLVPPALQSYL 485
++F H +NAT CA R + A+LE N Q + + VP L+ ++
Sbjct: 420 VEFVHMLNATMCATTRTICAILE-NYQTEKGITVPEKLKEFM 460
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 35.4 bits (80), Expect = 0.13
Identities = 32/145 (22%), Positives = 63/145 (43%), Gaps = 11/145 (7%)
Query: 50 EGYSALPQLDIERFCACPEEAAHALELRKGELRSADL----------PAIISTWQELRQL 99
E +A Q ++ A + AL +++GE++ DL A+ +ELR
Sbjct: 1995 EASTATLQASLDACQAHSRQLEEALRIQEGEIQDQDLRYQEDVQQLQQALAQRDEELRHQ 2054
Query: 100 QEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQL 159
QE+ + LE+ A + + Q+ G+ +++ + +GL RE++ L +L
Sbjct: 2055 QEREQLLEKSLAQRVQE-NMIQEKQNLGQEREEEEIRGLHQSVRELQLTLAQKEQEILEL 2113
Query: 160 EEQFYLQALKLPNQTHPDVPVGDES 184
E L+ +H P+ ++S
Sbjct: 2114 RETQQRNNLEALPHSHKTSPMEEQS 2138
Score = 30.8 bits (68), Expect = 3.1
Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 5/91 (5%)
Query: 75 ELRKGELRSADLP-AIISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDP 133
EL K LP A+ Q+L +EQIR LE+++ E R +L +Q ++D
Sbjct: 1481 ELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDR----ETQRNVLEHQLLELEKKDQ 1536
Query: 134 KYQGLRARGREIRKELVHLYPREAQLEEQFY 164
+ R + ++++K+LV L +LEE +
Sbjct: 1537 MIESQRGQVQDLKKQLVTLECLALELEENHH 1567
>gi|218749820 hypothetical protein LOC84221 isoform 1 [Homo sapiens]
Length = 340
Score = 34.3 bits (77), Expect = 0.28
Identities = 46/149 (30%), Positives = 62/149 (41%), Gaps = 20/149 (13%)
Query: 360 GLEQSSQLLEEFLSL--QMEILTELGLHFRVLDMPTQELG----LPAYRKFDIEAWMPGR 413
G E S+LL E L Q+ +L E + R+L QE G LP EA PG
Sbjct: 4 GGELMSRLLSENADLKKQVRLLKENQMLRRLLSQSCQEGGGHDLLPPRAHAYPEAGSPGS 63
Query: 414 G--RFGEVTSASNC-TDFQSRRLHIMFQTEAGELQFAHTVNATACAVPRLLIALLESNQQ 470
G FG TS ++ + Q+ L + + A T + CA P +Q
Sbjct: 64 GVPDFGRFTSVADTPSQLQTSSLEDLLCSHAPLSSEDDT--SPGCAAP---------SQA 112
Query: 471 KDGSVLVPPALQSYLGTDRITAPTHVPLQ 499
+ L PP S+ GTDR +P PLQ
Sbjct: 113 PFKAFLSPPEPHSHRGTDRKLSPLLSPLQ 141
>gi|20070228 nucleobindin 1 [Homo sapiens]
Length = 461
Score = 33.5 bits (75), Expect = 0.48
Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 19/101 (18%)
Query: 100 QEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQG-LRARGREIRKELVHLYPREAQ 158
+E++R EEE AA EA A + S E + + QG L A+ RE+++ ++H+ R+ Q
Sbjct: 344 EEELRRFEEELAA-REAELNAKAQRLSQETEALGRSQGRLEAQKRELQQAVLHMEQRKQQ 402
Query: 159 LEEQFYLQALKLPN-------QTHPD-------VPVGDESQ 185
++Q Q K P + HPD P GD+ +
Sbjct: 403 QQQQ---QGHKAPAAHPEGQLKFHPDTDDVPVPAPAGDQKE 440
>gi|109715862 gem (nuclear organelle) associated protein 8 [Homo
sapiens]
Length = 242
Score = 33.5 bits (75), Expect = 0.48
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Query: 308 FMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQL 367
F DH VA++D P CSS+ +R +GQ PR R+ TK + +E S
Sbjct: 76 FYDHHVAWQDYP----CSSSHFR---RSGQHPRYSSRIQASTKEDQALSKEEEMETESDA 128
Query: 368 LEEFLSLQMEILTELGLHFRVLDMPTQE 395
E MEI EL +F + +E
Sbjct: 129 EVECDLSNMEITEELRQYFAETERHREE 156
>gi|109715864 gem (nuclear organelle) associated protein 8 [Homo
sapiens]
Length = 242
Score = 33.5 bits (75), Expect = 0.48
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Query: 308 FMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQL 367
F DH VA++D P CSS+ +R +GQ PR R+ TK + +E S
Sbjct: 76 FYDHHVAWQDYP----CSSSHFR---RSGQHPRYSSRIQASTKEDQALSKEEEMETESDA 128
Query: 368 LEEFLSLQMEILTELGLHFRVLDMPTQE 395
E MEI EL +F + +E
Sbjct: 129 EVECDLSNMEITEELRQYFAETERHREE 156
>gi|8923481 gem (nuclear organelle) associated protein 8 [Homo
sapiens]
Length = 242
Score = 33.5 bits (75), Expect = 0.48
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Query: 308 FMDHTVAFRDLPVRMVCSSTCYRAETNTGQEPRGLYRVHHFTKVEMFGVTGPGLEQSSQL 367
F DH VA++D P CSS+ +R +GQ PR R+ TK + +E S
Sbjct: 76 FYDHHVAWQDYP----CSSSHFR---RSGQHPRYSSRIQASTKEDQALSKEEEMETESDA 128
Query: 368 LEEFLSLQMEILTELGLHFRVLDMPTQE 395
E MEI EL +F + +E
Sbjct: 129 EVECDLSNMEITEELRQYFAETERHREE 156
>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
Length = 1060
Score = 33.1 bits (74), Expect = 0.63
Identities = 38/159 (23%), Positives = 68/159 (42%), Gaps = 17/159 (10%)
Query: 93 WQELRQLQEQIRSLEEE-KAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVH 151
W+E QLQ+ +R L E + EA + + E QQ + + + +E RKE+
Sbjct: 808 WEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQA 867
Query: 152 LYP--REAQLEEQFYLQALKLPNQTHPDVPVGDESQARVLHMVGDKPVFSFQPRGHLEIG 209
+ AQ + Q L AL+ + + P S+ L ++G R +
Sbjct: 868 MVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIG---------RLQTRLK 918
Query: 210 EKLDIIRQKRLSHVSGHRSYYLRGAGALLQHGLVNFTFN 248
E+ DII+Q ++ R ++ + + H +F+FN
Sbjct: 919 EREDIIKQ-----LTEERRFHYAAFPSAMSHRNRSFSFN 952
>gi|27597085 tropomyosin 1 alpha chain isoform 5 [Homo sapiens]
Length = 284
Score = 32.7 bits (73), Expect = 0.82
Identities = 27/112 (24%), Positives = 48/112 (42%), Gaps = 18/112 (16%)
Query: 68 EEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQDSG 127
EE A L + + +L A+ A +S + Q+R LEE+ + + ++AL+A +D
Sbjct: 163 EEVARKLVIIESDLERAEERAELS--------EGQVRQLEEQLRIMDQTLKALMAAEDKY 214
Query: 128 EVQQD----------PKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALK 169
++D K + R + + L LE++ Y Q LK
Sbjct: 215 SQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSIDDLEDELYAQKLK 266
>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
Length = 717
Score = 32.7 bits (73), Expect = 0.82
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 75 ELRKGELRSADLPAIISTWQ----ELRQLQEQIRSLEEEKAAVTEAVRAL 120
ELR+ R+ L A +++ + ELR+L+ Q+R LEE A E R L
Sbjct: 299 ELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQL 348
>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
Length = 719
Score = 32.7 bits (73), Expect = 0.82
Identities = 19/50 (38%), Positives = 28/50 (56%), Gaps = 4/50 (8%)
Query: 75 ELRKGELRSADLPAIISTWQ----ELRQLQEQIRSLEEEKAAVTEAVRAL 120
ELR+ R+ L A +++ + ELR+L+ Q+R LEE A E R L
Sbjct: 299 ELRQSSERAGQLEATLTSCRRRLGELRELRRQVRQLEERNAGHAERTRQL 348
>gi|44890059 involucrin [Homo sapiens]
Length = 585
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/171 (23%), Positives = 65/171 (38%), Gaps = 13/171 (7%)
Query: 37 EKRNRNLLYEYAREGYSALPQLDIERFCACPEEAAHALELRKGELRSADLPAIISTWQEL 96
E++ L +EG LP+ E PE+ LEL + + +LP EL
Sbjct: 177 EQQEGQLELPEQQEGQLELPEQQ-EGQLELPEQQEGQLELPEQQEGQLELPEQQEGQLEL 235
Query: 97 RQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPRE 156
Q QE L E++ E L+ Q G+++ +G E +L +L +E
Sbjct: 236 PQQQEGQLELSEQQEGQLE-----LSEQQEGQLKHLEHQEGQLEVPEEQMGQLKYLEQQE 290
Query: 157 AQLEEQFYLQALKLPNQTHPDVPVGDESQARVLHMVGDKPVFSFQPRGHLE 207
QL+ + P++P Q + L +P Q G LE
Sbjct: 291 GQLKHLD-------QQEKQPELPEQQMGQLKHLEQQEGQPKHLEQQEGQLE 334
>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
[Homo sapiens]
Length = 871
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 18/164 (10%)
Query: 67 PEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEK-------AAVTEAVRA 119
P + L + S I+ QELR+L+E++R L E A + A
Sbjct: 161 PGRRGRSWGLEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEA 220
Query: 120 LLANQDSGEVQQDPKYQGLRA--RGRE-IRKELVHLYPREAQLEEQFYLQALKLPNQTHP 176
L + +G + +GLRA G E +RK L RE + ++ + + L Q H
Sbjct: 221 LARAEKAGRAEA----EGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHE 276
Query: 177 DVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRL 220
+ S+A L +K + S + R E E + R+ L
Sbjct: 277 EALSSLTSKAEGL----EKSLSSLETRRAGEAKELAEAQREAEL 316
>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
[Homo sapiens]
Length = 835
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 18/164 (10%)
Query: 67 PEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEK-------AAVTEAVRA 119
P + L + S I+ QELR+L+E++R L E A + A
Sbjct: 125 PGRRGRSWGLEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEA 184
Query: 120 LLANQDSGEVQQDPKYQGLRA--RGRE-IRKELVHLYPREAQLEEQFYLQALKLPNQTHP 176
L + +G + +GLRA G E +RK L RE + ++ + + L Q H
Sbjct: 185 LARAEKAGRAEA----EGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHE 240
Query: 177 DVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRL 220
+ S+A L +K + S + R E E + R+ L
Sbjct: 241 EALSSLTSKAEGL----EKSLSSLETRRAGEAKELAEAQREAEL 280
>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
[Homo sapiens]
Length = 782
Score = 32.3 bits (72), Expect = 1.1
Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 18/164 (10%)
Query: 67 PEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEK-------AAVTEAVRA 119
P + L + S I+ QELR+L+E++R L E A + A
Sbjct: 72 PGRRGRSWGLEGSQALSQQAEVIVRQLQELRRLEEEVRLLRETSLQQKMRLEAQAMELEA 131
Query: 120 LLANQDSGEVQQDPKYQGLRA--RGRE-IRKELVHLYPREAQLEEQFYLQALKLPNQTHP 176
L + +G + +GLRA G E +RK L RE + ++ + + L Q H
Sbjct: 132 LARAEKAGRAEA----EGLRAALAGAEVVRKNLEEGSQRELEEVQRLHQEQLSSLTQAHE 187
Query: 177 DVPVGDESQARVLHMVGDKPVFSFQPRGHLEIGEKLDIIRQKRL 220
+ S+A L +K + S + R E E + R+ L
Sbjct: 188 EALSSLTSKAEGL----EKSLSSLETRRAGEAKELAEAQREAEL 227
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 32.0 bits (71), Expect = 1.4
Identities = 20/92 (21%), Positives = 44/92 (47%), Gaps = 1/92 (1%)
Query: 94 QELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLY 153
+++ + +EQ++ EE+ E +R E Q + + ++ + ++RK+ +
Sbjct: 206 EQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMR 265
Query: 154 PREAQLEEQFYLQALKLPNQTHPDVPVGDESQ 185
+E Q+ EQ Q LK QT + G++ +
Sbjct: 266 EQEEQMREQ-EEQMLKQKEQTEQEEQTGEQEE 296
>gi|194394141 nucleolar preribosomal-associated protein 1 [Homo
sapiens]
Length = 2271
Score = 31.6 bits (70), Expect = 1.8
Identities = 44/160 (27%), Positives = 65/160 (40%), Gaps = 24/160 (15%)
Query: 83 SADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARG 142
SA + +++ + Q Q+ L A+T++V L N+ +G PK
Sbjct: 1049 SAGVLQLLAASAPILQNIGQLGLLARYSEAITQSVLKELQNRRAGPATSPPKTPPQLEAL 1108
Query: 143 REIRKELVHLYPREAQLEEQFYLQALKLPNQTH--PDVPVGDESQARVLHMVGDKPV--F 198
+E+ H Y AQL E L L LP +TH P + R L+ +G V
Sbjct: 1109 QEL-----HPYMEGAQLRE-VTLALLSLP-ETHLVTQQPTKSPGKERHLNALGKTLVQLL 1161
Query: 199 SFQPRGHLEIGEKLDIIRQKRLSHVSGHRSYYLRGAGALL 238
+ P+ L+ GE L S Y+RG GALL
Sbjct: 1162 TCSPQDQLQSGELL-------------WSSEYVRGLGALL 1188
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 31.2 bits (69), Expect = 2.4
Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 8/75 (10%)
Query: 99 LQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQ 158
LQE EEE+ + EA D +VQ+ + + LR RE+ KEL ++ R
Sbjct: 581 LQEAWGKPEEEQRGLQEA------QLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQL 634
Query: 159 LEEQFYLQALKLPNQ 173
LE + LQAL+ Q
Sbjct: 635 LEGK--LQALQADYQ 647
Score = 29.6 bits (65), Expect = 6.9
Identities = 28/112 (25%), Positives = 55/112 (49%), Gaps = 13/112 (11%)
Query: 82 RSADLPAIISTWQE-LRQLQEQIRSLEEEKAAVTEAVRAL---LANQDSGEVQQDPKYQG 137
R +L A S+W+E L +L+ + + +EEK + + VR+L L ++ Q
Sbjct: 472 RLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSD 531
Query: 138 LRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPV-GDESQARV 188
L + +++ ++ HL + LE +L P++PV G++++A V
Sbjct: 532 LEEQKKQLIQDKDHLSQQVGMLE--------RLAGPPGPELPVAGEKNEALV 575
>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
isoform 1 [Homo sapiens]
Length = 1166
Score = 31.2 bits (69), Expect = 2.4
Identities = 36/147 (24%), Positives = 65/147 (44%), Gaps = 17/147 (11%)
Query: 94 QELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLY 153
++ R+ QE+ R LEE + E A ++ V+++ +Y +R R++ +E HL
Sbjct: 426 EQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEY--IR---RQLEEEQRHLE 480
Query: 154 PREAQL--EEQFYLQALKLPNQTHPDVPVGDESQARVLHMVGDKPVF-SFQPRGHLEIGE 210
+ QL E+ L + P+ H P + + KP F + +P+ H E +
Sbjct: 481 VLQQQLLQEQAMLLHDHRRPHPQHSQQPPPPQQER-------SKPSFHAPEPKAHYEPAD 533
Query: 211 KLD--IIRQKRLSHVSGHRSYYLRGAG 235
+ +R S V R L+G+G
Sbjct: 534 RAREVPVRTTSRSPVLSRRDSPLQGSG 560
>gi|239748049 PREDICTED: similar to NADH dehydrogenase [ubiquinone]
1 alpha subcomplex subunit 10, mitochondrial [Homo
sapiens]
Length = 128
Score = 30.8 bits (68), Expect = 3.1
Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 124 QDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPVGDE 183
QDS +V +D +Y +G ++++ LY ++++F + P+V +G
Sbjct: 37 QDSKKVVEDIEYLKFD-KGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVTIGAH 95
Query: 184 SQARVLHMVGDKPVFSFQPRGHLEIGEK 211
RVLH + P + P + E+G+K
Sbjct: 96 QTDRVLHQFRELPGRKYSPGYNTEVGDK 123
>gi|27477127 keratin 82 [Homo sapiens]
Length = 513
Score = 30.8 bits (68), Expect = 3.1
Identities = 26/113 (23%), Positives = 54/113 (47%), Gaps = 5/113 (4%)
Query: 365 SQLLEEFLSLQMEILTELGLHFRVLDMPTQELGLPAYRKFDIEAWMPGRGRFGEVTSASN 424
SQ+ E + ++M+ EL + + ++ Q + + K + EAW R VT+ ++
Sbjct: 266 SQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNH 325
Query: 425 CTDFQSRRLHIMFQTEAGE--LQFAHTVNATACAVPRLLIALLESNQQKDGSV 475
C + ++R+ I+ + + Q V A C +L A+ E+ QQ + ++
Sbjct: 326 CDNLRNRKNEILEMNKLIQRLQQETENVKAQRC---KLEGAIAEAEQQGEAAL 375
>gi|4758768 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10,
42kDa precursor [Homo sapiens]
Length = 355
Score = 30.8 bits (68), Expect = 3.1
Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 124 QDSGEVQQDPKYQGLRARGREIRKELVHLYPREAQLEEQFYLQALKLPNQTHPDVPVGDE 183
QDS +V +D +Y +G ++++ LY ++++F + P+V +G
Sbjct: 264 QDSKKVVEDIEYLKFD-KGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVTIGAH 322
Query: 184 SQARVLHMVGDKPVFSFQPRGHLEIGEK 211
RVLH + P + P + E+G+K
Sbjct: 323 QTDRVLHQFRELPGRKYSPGYNTEVGDK 350
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 30.8 bits (68), Expect = 3.1
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 3/68 (4%)
Query: 94 QELRQLQEQIRSLEEEKAAVTEAVRALLANQDSGEVQQDPKYQGLRARGREIRKELVHLY 153
Q+L EQ+ + E+ E + LA+ D Q K + ++A+G E ++E L
Sbjct: 1531 QKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQQEAQRL- 1589
Query: 154 PREAQLEE 161
+AQL E
Sbjct: 1590 --QAQLNE 1595
Score = 30.0 bits (66), Expect = 5.3
Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 16/106 (15%)
Query: 53 SALPQLDIERFCACPEEAAHALELRKGE---------LRSADLPAIISTWQELRQLQEQI 103
+AL + +E F E AHAL ++G+ L +A + + Q ++QL+EQ+
Sbjct: 1036 NALNEQRVE-FATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQL 1094
Query: 104 RSLEEEKAAVTEAVRALLANQDSGEVQ-QDPKYQGLRARGREIRKE 148
E+E A+ + A ++ +G + PK + LRA ++ ++
Sbjct: 1095 AKKEKEHASGSGA-----QSEAAGRTEPTGPKLEALRAEVSKLEQQ 1135
>gi|45439327 periplakin [Homo sapiens]
Length = 1756
Score = 30.8 bits (68), Expect = 3.1
Identities = 37/141 (26%), Positives = 58/141 (41%), Gaps = 18/141 (12%)
Query: 33 SFTTEKRNRNLLYEYAREGYSALPQ-LDIERFCACPEEAAHALELRKGELRSADLPAIIS 91
SF +K R EG + + L +E+ A E + + E A +
Sbjct: 1092 SFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKAR-----A 1146
Query: 92 TWQELRQLQEQIRSLEEE--KAAVTEAVRALLANQDSGE----------VQQDPKYQGLR 139
+ +E +L +I +LEEE K V E VR ++ E V+Q+ KY+G
Sbjct: 1147 SQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRGAE 1206
Query: 140 ARGREIRKELVHLYPREAQLE 160
+ R + EL L R Q+E
Sbjct: 1207 EQLRSYQSELEALRRRGPQVE 1227
>gi|33589848 transferrin receptor 2 [Homo sapiens]
Length = 801
Score = 30.4 bits (67), Expect = 4.1
Identities = 24/74 (32%), Positives = 37/74 (50%), Gaps = 8/74 (10%)
Query: 74 LELRKGELRSADLPAIISTWQELRQLQEQIR--SLEEE------KAAVTEAVRALLANQD 125
L+ +G L +DL A+ + +L++ IR SL E AA+T+ +RA L+ Q
Sbjct: 128 LDFHQGRLYWSDLQAMFLQFLGEGRLEDTIRQTSLRERVAGSAGMAALTQDIRAALSRQK 187
Query: 126 SGEVQQDPKYQGLR 139
V D Y GL+
Sbjct: 188 LDHVWTDTHYVGLQ 201
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 30.4 bits (67), Expect = 4.1
Identities = 38/161 (23%), Positives = 65/161 (40%), Gaps = 20/161 (12%)
Query: 12 LLTRRGFRPRGGCISNDSPRRSFTTEKRNRNLLYEYAREGYSALPQLDIER------FCA 65
++TR +P + + S + + LL + L Q ER + A
Sbjct: 54 IVTRNLSQPESPVLLPATEMASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNA 113
Query: 66 CPEEAAHALELRKGELRSADLPAIISTWQELRQLQEQIRSLEEEKAAVTEAVRALLANQD 125
E AL L GEL + + ++ ELR R L+EE+A+ ++A Q
Sbjct: 114 VSERLEQALRLEPGELETQEPRGLVRQSVELR------RQLQEEQASYRRKLQAYQEGQQ 167
Query: 126 SGEVQQDPKYQG----LRARGREIRKELVHLYPREAQLEEQ 162
+ Q + QG + R E+ ++L+ R +LE+Q
Sbjct: 168 R-QAQLVQRLQGKILQYKKRCSELEQQLLE---RSGELEQQ 204
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 30.4 bits (67), Expect = 4.1
Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 466 ESNQQKDGSVLVPPALQ--SYLGTDRITAPTHVPLQYIGPNQPRKPGLP 512
ES++ DG PA Q S +GT T+P +Q G N+ RKP LP
Sbjct: 1045 ESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP 1093
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 30.4 bits (67), Expect = 4.1
Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 2/49 (4%)
Query: 466 ESNQQKDGSVLVPPALQ--SYLGTDRITAPTHVPLQYIGPNQPRKPGLP 512
ES++ DG PA Q S +GT T+P +Q G N+ RKP LP
Sbjct: 1045 ESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP 1093
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,677,726
Number of Sequences: 37866
Number of extensions: 967323
Number of successful extensions: 3278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 51
Number of HSP's that attempted gapping in prelim test: 3196
Number of HSP's gapped (non-prelim): 137
length of query: 518
length of database: 18,247,518
effective HSP length: 107
effective length of query: 411
effective length of database: 14,195,856
effective search space: 5834496816
effective search space used: 5834496816
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.