Guide to the Human Genome
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Search of human proteins with 8922188

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8922188 F-box only protein 6 [Homo sapiens]
         (293 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8922188 F-box only protein 6 [Homo sapiens]                        621   e-178
gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]                 405   e-113
gi|62388868 F-box protein 44 isoform 1 [Homo sapiens]                 405   e-113
gi|15812198 F-box only protein 2 [Homo sapiens]                       264   8e-71
gi|34878749 F-box protein 44 isoform 2 [Homo sapiens]                 209   2e-54
gi|34878753 F-box protein 44 isoform 2 [Homo sapiens]                 209   2e-54
gi|30520327 F-box protein 27 [Homo sapiens]                           199   3e-51
gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens]               174   8e-44
gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens]               174   8e-44
gi|47825361 non-specific cytotoxic cell receptor protein 1 homol...    96   5e-20
gi|27312027 F-box only protein 16 [Homo sapiens]                       41   0.001
gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo sap...    40   0.002
gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo sap...    40   0.002
gi|8923179 F-box and leucine-rich repeat protein 12 [Homo sapiens]     39   0.004
gi|83035136 F-box protein 31 [Homo sapiens]                            37   0.021
gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [H...    33   0.30 
gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [H...    33   0.30 
gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [H...    33   0.30 
gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [H...    33   0.30 
gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [H...    33   0.30 
gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens]           33   0.30 
gi|148922963 F-box and leucine-rich repeat protein 21 [Homo sapi...    30   3.3  
gi|153792756 hypothetical protein LOC196951 [Homo sapiens]             30   3.3  
gi|226442878 ADAMTS-like 5 [Homo sapiens]                              29   4.3  
gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens]    29   4.3  
gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapi...    29   4.3  
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    29   5.6  
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    29   5.6  
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    29   5.6  
gi|157426875 F-box and leucine-rich repeat protein 18 [Homo sapi...    29   5.6  

>gi|8922188 F-box only protein 6 [Homo sapiens]
          Length = 293

 Score =  621 bits (1602), Expect = e-178
 Identities = 293/293 (100%), Positives = 293/293 (100%)

Query: 1   MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR 60
           MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR
Sbjct: 1   MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLR 60

Query: 61  EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH 120
           EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH
Sbjct: 61  EGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAH 120

Query: 121 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT 180
           GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT
Sbjct: 121 GTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCT 180

Query: 181 YQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQ 240
           YQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQ
Sbjct: 181 YQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQ 240

Query: 241 YWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQSPYRAVVQIF 293
           YWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQSPYRAVVQIF
Sbjct: 241 YWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQSPYRAVVQIF 293


>gi|34878735 F-box protein 44 isoform 1 [Homo sapiens]
          Length = 255

 Score =  405 bits (1042), Expect = e-113
 Identities = 190/253 (75%), Positives = 210/253 (83%)

Query: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDW 68
           A+ +INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDL+TLWKRKCLREGFIT+DW
Sbjct: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61

Query: 69  DQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPK 128
           DQPVADWKIFYFLRSLHRNLL NPCAEE    W +D NGGD WKVE L      +FP+ +
Sbjct: 62  DQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQ 121

Query: 129 VKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLA 188
           VKKYFVTSY  CLKSQ+VDL AEGYWEEL+DT RPDI VKDWFAAR DCG  YQL VQL 
Sbjct: 122 VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLL 181

Query: 189 SADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGP 248
           S+ +  L +F+P P TIQQ ++A W EVS+TFS+YP GVRYI FQHGG DT YWAGWYGP
Sbjct: 182 SSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGP 241

Query: 249 RVTNSSIVVSPKM 261
           RVTNSSI + P +
Sbjct: 242 RVTNSSITIGPPL 254


>gi|62388868 F-box protein 44 isoform 1 [Homo sapiens]
          Length = 255

 Score =  405 bits (1042), Expect = e-113
 Identities = 190/253 (75%), Positives = 210/253 (83%)

Query: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDW 68
           A+ +INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDL+TLWKRKCLREGFIT+DW
Sbjct: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61

Query: 69  DQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPK 128
           DQPVADWKIFYFLRSLHRNLL NPCAEE    W +D NGGD WKVE L      +FP+ +
Sbjct: 62  DQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQ 121

Query: 129 VKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLA 188
           VKKYFVTSY  CLKSQ+VDL AEGYWEEL+DT RPDI VKDWFAAR DCG  YQL VQL 
Sbjct: 122 VKKYFVTSYYTCLKSQVVDLKAEGYWEELMDTTRPDIEVKDWFAARPDCGSKYQLCVQLL 181

Query: 189 SADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGP 248
           S+ +  L +F+P P TIQQ ++A W EVS+TFS+YP GVRYI FQHGG DT YWAGWYGP
Sbjct: 182 SSAHAPLGTFQPDPATIQQKSDAKWREVSHTFSNYPPGVRYIWFQHGGVDTHYWAGWYGP 241

Query: 249 RVTNSSIVVSPKM 261
           RVTNSSI + P +
Sbjct: 242 RVTNSSITIGPPL 254


>gi|15812198 F-box only protein 2 [Homo sapiens]
          Length = 296

 Score =  264 bits (674), Expect = 8e-71
 Identities = 128/255 (50%), Positives = 170/255 (66%), Gaps = 3/255 (1%)

Query: 8   AALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKD 67
           AA   ++ELPE +LL +   +PA +L+  CRLVC  W++L+D   LW  KC +EG + + 
Sbjct: 42  AAAAYLDELPEPLLLRVLAALPAAELVQACRLVCLRWKELVDGAPLWLLKCQQEGLVPEG 101

Query: 68  WDQPVAD-WKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFP- 125
             +   D W+ FYFL    RNLLRNPC EED+  W    +GGD W+VE LPG  G +F  
Sbjct: 102 GVEEERDHWQQFYFLSKRRRNLLRNPCGEEDLEGWCDVEHGGDGWRVEELPGDSGVEFTH 161

Query: 126 DPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKV 185
           D  VKKYF +S+E C K+Q++DL AEGYWEELLDT +P IVVKDW++ R+D GC Y+L V
Sbjct: 162 DESVKKYFASSFEWCRKAQVIDLQAEGYWEELLDTTQPAIVVKDWYSGRSDAGCLYELTV 221

Query: 186 QLASADYFVLASFEPPPVTI-QQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAG 244
           +L S    VLA F    V + Q  +   W E+S+TF+DY  GVR++ F+HGG+D+ YW G
Sbjct: 222 KLLSEHENVLAEFSSGQVAVPQDSDGGGWMEISHTFTDYGPGVRFVRFEHGGQDSVYWKG 281

Query: 245 WYGPRVTNSSIVVSP 259
           W+G RVTNSS+ V P
Sbjct: 282 WFGARVTNSSVWVEP 296


>gi|34878749 F-box protein 44 isoform 2 [Homo sapiens]
          Length = 224

 Score =  209 bits (532), Expect = 2e-54
 Identities = 96/122 (78%), Positives = 105/122 (86%)

Query: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDW 68
           A+ +INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDL+TLWKRKCLREGFIT+DW
Sbjct: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61

Query: 69  DQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPK 128
           DQPVADWKIFYFLRSLHRNLL NPCAEE    W +D NGGD WKVE L      +FP+ +
Sbjct: 62  DQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQ 121

Query: 129 VK 130
           V+
Sbjct: 122 VR 123


>gi|34878753 F-box protein 44 isoform 2 [Homo sapiens]
          Length = 224

 Score =  209 bits (532), Expect = 2e-54
 Identities = 96/122 (78%), Positives = 105/122 (86%)

Query: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDW 68
           A+ +INELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDL+TLWKRKCLREGFIT+DW
Sbjct: 2   AVGNINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLVTLWKRKCLREGFITEDW 61

Query: 69  DQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPK 128
           DQPVADWKIFYFLRSLHRNLL NPCAEE    W +D NGGD WKVE L      +FP+ +
Sbjct: 62  DQPVADWKIFYFLRSLHRNLLHNPCAEEGFEFWSLDVNGGDEWKVEDLSRDQRKEFPNDQ 121

Query: 129 VK 130
           V+
Sbjct: 122 VR 123


>gi|30520327 F-box protein 27 [Homo sapiens]
          Length = 283

 Score =  199 bits (505), Expect = 3e-51
 Identities = 111/272 (40%), Positives = 152/272 (55%), Gaps = 19/272 (6%)

Query: 4   PHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGF 63
           P  + ALD +++LP  +LL + +HVP R LL  CR VC  WR L+D   LW     R+  
Sbjct: 18  PEPEEALD-LSQLPPELLLVVLSHVPPRTLLGRCRQVCRGWRALVDGQALWLLILARDHG 76

Query: 64  IT--------KDWDQPVADWKI-----FYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDR 110
            T        +    P  + +      F   R + RNL+RNPC +E +  W +  +GGD 
Sbjct: 77  ATGRALLHLARSCQSPARNARPCPLGRFCARRPIGRNLIRNPCGQEGLRKWMVQ-HGGDG 135

Query: 111 WKVESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDW 170
           W VE     + T  P    +  FVTS+  C K Q++DL  EG W ELLD+ R +I V DW
Sbjct: 136 WVVEE----NRTTVPGAPSQTCFVTSFSWCCKKQVLDLEEEGLWPELLDSGRIEICVSDW 191

Query: 171 FAARADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYI 230
           + AR D GC Y+L VQL  A+  VL  F   P  I QWNN     V++ FS+   GVR++
Sbjct: 192 WGARHDSGCMYRLLVQLLDANQTVLDKFSAVPDPIPQWNNNACLHVTHVFSNIKMGVRFV 251

Query: 231 LFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMT 262
            F+H G+DTQ+WAG YG RVTNSS++V  +++
Sbjct: 252 SFEHRGQDTQFWAGHYGARVTNSSVIVRVRLS 283


>gi|22325388 F-box protein FBG4 isoform 1 [Homo sapiens]
          Length = 287

 Score =  174 bits (441), Expect = 8e-44
 Identities = 91/269 (33%), Positives = 145/269 (53%), Gaps = 25/269 (9%)

Query: 12  SINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLW----------------- 54
           +++ LP  +L+++ +HVP R L+  CR VC  WRD++D  T+W                 
Sbjct: 26  ALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYA 85

Query: 55  -KRKCLREGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKV 113
             ++CL      +++  P+     +       RNL+ N C E+    W+++ +GG+ W +
Sbjct: 86  VAQRCLPSNEDKEEF--PLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVE-HGGNGWAI 142

Query: 114 ESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAA 173
           E     + T  P    +  FVTS+E C K QLVDLV EG W+ELLD+ + +I V DW+ A
Sbjct: 143 EK----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGA 198

Query: 174 RADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQ 233
           R +CGC YQL+V+L       +  F   P  + QW      +VS+ F+++ +G+RY+ F+
Sbjct: 199 RENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFE 258

Query: 234 HGGRDTQYWAGWYGPRVTNSSIVVSPKMT 262
             GRD   W G YG  VT+SS+ V  +++
Sbjct: 259 QYGRDVSSWVGHYGALVTHSSVRVRIRLS 287


>gi|18643385 F-box protein FBG4 isoform 2 [Homo sapiens]
          Length = 278

 Score =  174 bits (441), Expect = 8e-44
 Identities = 91/269 (33%), Positives = 145/269 (53%), Gaps = 25/269 (9%)

Query: 12  SINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLW----------------- 54
           +++ LP  +L+++ +HVP R L+  CR VC  WRD++D  T+W                 
Sbjct: 17  ALDALPPELLVQVLSHVPPRSLVTRCRPVCRAWRDIVDGPTVWLLQLARDRSAEGRALYA 76

Query: 55  -KRKCLREGFITKDWDQPVADWKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKV 113
             ++CL      +++  P+     +       RNL+ N C E+    W+++ +GG+ W +
Sbjct: 77  VAQRCLPSNEDKEEF--PLCALARYCLRAPFGRNLIFNSCGEQGFRGWEVE-HGGNGWAI 133

Query: 114 ESLPGAHGTDFPDPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAA 173
           E     + T  P    +  FVTS+E C K QLVDLV EG W+ELLD+ + +I V DW+ A
Sbjct: 134 EK----NLTPVPGAPSQTCFVTSFEWCSKRQLVDLVMEGVWQELLDSAQIEICVADWWGA 189

Query: 174 RADCGCTYQLKVQLASADYFVLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQ 233
           R +CGC YQL+V+L       +  F   P  + QW      +VS+ F+++ +G+RY+ F+
Sbjct: 190 RENCGCVYQLRVRLLDVYEKEVVKFSASPDPVLQWTERGCRQVSHVFTNFGKGIRYVSFE 249

Query: 234 HGGRDTQYWAGWYGPRVTNSSIVVSPKMT 262
             GRD   W G YG  VT+SS+ V  +++
Sbjct: 250 QYGRDVSSWVGHYGALVTHSSVRVRIRLS 278


>gi|47825361 non-specific cytotoxic cell receptor protein 1 homolog
           [Homo sapiens]
          Length = 275

 Score = 95.5 bits (236), Expect = 5e-20
 Identities = 65/184 (35%), Positives = 89/184 (48%), Gaps = 5/184 (2%)

Query: 75  WKIFYFLRSLHRNLLRNPCAEEDMFAWQIDFNGGDRWKVESLPGAHGTDFPDPKVKKYFV 134
           WK+    R L+RNLLR+P  E           G  +  +E+L    G      K+++   
Sbjct: 92  WKLLLLRRPLYRNLLRSPNPEGINIYEPAPPTGPTQRPLETLGNFRGWYIRTEKLQQ--- 148

Query: 135 TSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAARADCGCTYQLKVQLASAD-YF 193
            +    +K Q VDL+AEG WEELLD  +P I V DWF       C Y+L V L +AD   
Sbjct: 149 -NQSWTVKQQCVDLLAEGLWEELLDDEQPAITVMDWFEDSRLDACVYELHVWLLAADRRT 207

Query: 194 VLASFEPPPVTIQQWNNATWTEVSYTFSDYPRGVRYILFQHGGRDTQYWAGWYGPRVTNS 253
           V+A     P T  +     W +VS+ F  Y  GVR+I F H  ++     G    RVT+S
Sbjct: 208 VIAQHHVAPRTSGRGPPGRWVQVSHVFRHYGPGVRFIHFLHKAKNRMEPGGLRRTRVTDS 267

Query: 254 SIVV 257
           S+ V
Sbjct: 268 SVSV 271


>gi|27312027 F-box only protein 16 [Homo sapiens]
          Length = 292

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 28/88 (31%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDW 68
           ALD   +LP  + L +F+ +  R L   C  VC  W++L +L  LW  KCLR  +     
Sbjct: 85  ALDFTTKLPRVLSLYIFSFLDPRSLC-RCAQVCWHWKNLAELDQLWMLKCLRFNWYINFS 143

Query: 69  DQPVAD--WKIFY--FLRSLHRNLLRNP 92
             P     WK  Y   ++ LH    + P
Sbjct: 144 PTPFEQGIWKKHYIQMVKELHITKPKTP 171


>gi|30795117 F-box only protein, helicase, 18 isoform 1 [Homo
           sapiens]
          Length = 1094

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLID--LMTLWKR 56
           AL  I  LP  +L  +F  +P   L  N  LVC LWR++I   L   WK+
Sbjct: 259 ALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIPWKK 308


>gi|30795119 F-box only protein, helicase, 18 isoform 2 [Homo
           sapiens]
          Length = 1043

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 20/50 (40%), Positives = 26/50 (52%), Gaps = 2/50 (4%)

Query: 9   ALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLID--LMTLWKR 56
           AL  I  LP  +L  +F  +P   L  N  LVC LWR++I   L   WK+
Sbjct: 208 ALSHICSLPSEVLRHVFAFLPVEDLYWNLSLVCHLWREIISDPLFIPWKK 257


>gi|8923179 F-box and leucine-rich repeat protein 12 [Homo
          sapiens]
          Length = 326

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 17/41 (41%), Positives = 28/41 (68%), Gaps = 1/41 (2%)

Query: 15 ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWK 55
          ELP+++LLE+F+++P R  +   R VC  W+ L+D   LW+
Sbjct: 6  ELPDSVLLEIFSYLPVRDRIRISR-VCHRWKRLVDDRWLWR 45


>gi|83035136 F-box protein 31 [Homo sapiens]
          Length = 539

 Score = 37.0 bits (84), Expect = 0.021
 Identities = 17/50 (34%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 12  SINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLRE 61
           S+ ELP  +L+E+F  +P   L  +   VC+ +R ++   T+W+R+C  E
Sbjct: 66  SLLELPPELLVEIFASLPGTDLP-SLAQVCTKFRRILHTDTIWRRRCREE 114


>gi|61743926 F-box and WD repeat domain containing 7 isoform 3 [Homo
           sapiens]
          Length = 589

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 1/52 (1%)

Query: 11  DSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREG 62
           D I+ LP+ + L + + +  + LL   +  C  WR L +   LW+ KC  EG
Sbjct: 161 DFISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 211


>gi|16117781 F-box and WD repeat domain containing 7 isoform 1 [Homo
           sapiens]
          Length = 707

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 1/52 (1%)

Query: 11  DSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREG 62
           D I+ LP+ + L + + +  + LL   +  C  WR L +   LW+ KC  EG
Sbjct: 279 DFISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 329


>gi|16117779 F-box and WD repeat domain containing 7 isoform 2 [Homo
           sapiens]
          Length = 627

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 1/52 (1%)

Query: 11  DSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREG 62
           D I+ LP+ + L + + +  + LL   +  C  WR L +   LW+ KC  EG
Sbjct: 199 DFISLLPKELALYVLSFLEPKDLLQAAQ-TCRYWRILAEDNLLWREKCKEEG 249


>gi|30795121 F-box and WD repeat domain containing 8 isoform 2 [Homo
           sapiens]
          Length = 532

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 15  ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDWDQPVAD 74
           +LP  + + +F ++  ++L   C  V   W+ + +   LW R C +EG +        + 
Sbjct: 52  QLPYELAINIFQYLDRKELG-RCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSC 110

Query: 75  WKIFY 79
           WK+ +
Sbjct: 111 WKLIF 115


>gi|30795123 F-box and WD repeat domain containing 8 isoform 1 [Homo
           sapiens]
          Length = 598

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 15/65 (23%), Positives = 31/65 (47%), Gaps = 1/65 (1%)

Query: 15  ELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKCLREGFITKDWDQPVAD 74
           +LP  + + +F ++  ++L   C  V   W+ + +   LW R C +EG +        + 
Sbjct: 118 QLPYELAINIFQYLDRKELG-RCAQVSKTWKVIAEDEVLWYRLCQQEGHLPDSSISDYSC 176

Query: 75  WKIFY 79
           WK+ +
Sbjct: 177 WKLIF 181


>gi|124248558 F-box and WD-40 domain protein 9 [Homo sapiens]
          Length = 458

 Score = 33.1 bits (74), Expect = 0.30
 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 5/62 (8%)

Query: 4   PHSKAALDSINE-----LPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKRKC 58
           P + + + +++E     LP  +LLE+ +++ AR +L     VC   RDL+     W+ + 
Sbjct: 65  PRAASRVSAVSEPGLLSLPPELLLEICSYLDARLVLHVLSRVCHALRDLVSDHVTWRLRA 124

Query: 59  LR 60
           LR
Sbjct: 125 LR 126


>gi|148922963 F-box and leucine-rich repeat protein 21 [Homo
          sapiens]
          Length = 434

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 12/56 (21%), Positives = 27/56 (48%), Gaps = 1/56 (1%)

Query: 1  MDAPHSKAALDSINELPENILLELFTHVPARQLLLNCRLVCSLWRDLIDLMTLWKR 56
          ++  H+   L     LP +++L++F ++P          VC  W ++  +  LW++
Sbjct: 30 LNQTHTHTVLLDWGSLPHHVVLQIFQYLPLLDRAC-ASSVCRRWNEVFHISDLWRK 84


>gi|153792756 hypothetical protein LOC196951 [Homo sapiens]
          Length = 508

 Score = 29.6 bits (65), Expect = 3.3
 Identities = 38/160 (23%), Positives = 65/160 (40%), Gaps = 16/160 (10%)

Query: 126 DPKVKKYFVTSYEMCLKSQLVDLVAEGYWEELLDTFRPDIVVKDWFAAR-ADCGCTYQLK 184
           D +V K + T +   L    + L+ + +W   L  FRPD   +D    R ++   T  + 
Sbjct: 182 DERVFKIWKTHF---LSEASIALLHDSFWWWFLHKFRPDRENQDCLFDRISESYVTLFMS 238

Query: 185 VQLASADYFVLASFEPPPVTIQQWNNATWTEV----SYTFSDYPR---GVRYILFQHGGR 237
           + L+  D F    F+  P  + Q   AT+ E     SY F+D  +   G    L+  G +
Sbjct: 239 IPLSRKDAF----FQIYPDCLAQAIYATFHEAFPESSYLFNDEFKEDLGNNIFLWCSGLK 294

Query: 238 DTQ-YWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKH 276
             + +W  W    ++ ++I  S K             Q+H
Sbjct: 295 PQKGFWIHWKLKELSTTTIHGSKKAPAKSVKERIADSQEH 334


>gi|226442878 ADAMTS-like 5 [Homo sapiens]
          Length = 471

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 19/61 (31%), Positives = 26/61 (42%)

Query: 224 PRGVRYILFQHGGRDTQYWAGWYGPRVTNSSIVVSPKMTRNQASSEAQPGQKHGQEEAAQ 283
           P G R+I  +H  R+     G  G  V N   VVSP  T   A +     +  G +E  Q
Sbjct: 213 PEGARHIRVEHRSRNHLALMGGDGRYVLNGHWVVSPPGTYEAAGTHVVYTRDTGPQETLQ 272

Query: 284 S 284
           +
Sbjct: 273 A 273


>gi|49574498 hypothetical protein LOC118461 isoform 2 [Homo sapiens]
          Length = 719

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 11/30 (36%), Positives = 19/30 (63%)

Query: 259 PKMTRNQASSEAQPGQKHGQEEAAQSPYRA 288
           P    N   +  QPG+KHG++E++++P  A
Sbjct: 199 PAEVSNTHQNSYQPGRKHGEQESSKNPEMA 228


>gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo
           sapiens]
          Length = 1435

 Score = 29.3 bits (64), Expect = 4.3
 Identities = 11/30 (36%), Positives = 19/30 (63%)

Query: 259 PKMTRNQASSEAQPGQKHGQEEAAQSPYRA 288
           P    N   +  QPG+KHG++E++++P  A
Sbjct: 199 PAEVSNTHQNSYQPGRKHGEQESSKNPEMA 228


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 3/49 (6%)

Query: 85  HRNLLRNPCAEEDMFAWQ---IDFNGGDRWKVESLPGAHGTDFPDPKVK 130
           H  L      +E +FAW+     FNGG R +    PGAH    P   VK
Sbjct: 212 HLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPGAHPACHPLSSVK 260


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 3/49 (6%)

Query: 85  HRNLLRNPCAEEDMFAWQ---IDFNGGDRWKVESLPGAHGTDFPDPKVK 130
           H  L      +E +FAW+     FNGG R +    PGAH    P   VK
Sbjct: 212 HLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPGAHPACHPLSSVK 260


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 3/49 (6%)

Query: 85  HRNLLRNPCAEEDMFAWQ---IDFNGGDRWKVESLPGAHGTDFPDPKVK 130
           H  L      +E +FAW+     FNGG R +    PGAH    P   VK
Sbjct: 212 HLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPGAHPACHPLSSVK 260


>gi|157426875 F-box and leucine-rich repeat protein 18 [Homo
          sapiens]
          Length = 718

 Score = 28.9 bits (63), Expect = 5.6
 Identities = 11/24 (45%), Positives = 16/24 (66%)

Query: 18 ENILLELFTHVPARQLLLNCRLVC 41
          + ILL + +HVP+  L+LN R  C
Sbjct: 33 DEILLHILSHVPSTDLILNVRRTC 56


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,422,602
Number of Sequences: 37866
Number of extensions: 548220
Number of successful extensions: 1036
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 991
Number of HSP's gapped (non-prelim): 49
length of query: 293
length of database: 18,247,518
effective HSP length: 101
effective length of query: 192
effective length of database: 14,423,052
effective search space: 2769225984
effective search space used: 2769225984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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