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Search of human proteins with 89062345
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89062345 PREDICTED: similar to mindbomb homolog 2 [Homo
sapiens]
(233 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89062345 PREDICTED: similar to mindbomb homolog 2 [Homo sapiens] 464 e-131
gi|21264330 mindbomb homolog 2 [Homo sapiens] 74 1e-13
gi|30348954 mindbomb homolog 1 [Homo sapiens] 64 1e-10
gi|89363047 death-associated protein kinase 1 [Homo sapiens] 63 2e-10
gi|20270347 ankyrin repeat domain 54 [Homo sapiens] 63 2e-10
gi|62988328 ankyrin repeat domain 50 [Homo sapiens] 62 3e-10
gi|34304381 inversin isoform a [Homo sapiens] 62 4e-10
gi|34304379 inversin isoform b [Homo sapiens] 62 4e-10
gi|194018403 ankyrin repeat domain 2 isoform b [Homo sapiens] 61 7e-10
gi|50511945 cajalin 2 isoform a [Homo sapiens] 61 9e-10
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens] 59 4e-09
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens] 59 4e-09
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens] 59 4e-09
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens] 59 4e-09
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens] 59 4e-09
gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribo... 59 4e-09
gi|96975023 ankyrin repeat and death domain containing 1A [Homo ... 59 5e-09
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ... 58 8e-09
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ... 58 8e-09
gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo sap... 57 1e-08
gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo sap... 57 1e-08
gi|32967601 ankyrin 3 isoform 1 [Homo sapiens] 57 1e-08
gi|116875852 HECT domain and ankyrin repeat containing, E3 ubiqu... 57 1e-08
gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo ... 56 3e-08
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 56 3e-08
gi|38327522 cardiac ankyrin repeat protein [Homo sapiens] 56 3e-08
gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo sa... 56 3e-08
gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo sa... 56 3e-08
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 55 4e-08
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 55 4e-08
>gi|89062345 PREDICTED: similar to mindbomb homolog 2 [Homo sapiens]
Length = 233
Score = 464 bits (1194), Expect = e-131
Identities = 233/233 (100%), Positives = 233/233 (100%)
Query: 1 MEPYYEPDSEFREPLTDVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHM 60
MEPYYEPDSEFREPLTDVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHM
Sbjct: 1 MEPYYEPDSEFREPLTDVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHM 60
Query: 61 AAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMG 120
AAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMG
Sbjct: 61 AAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMG 120
Query: 121 KTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLSAKEGDEDEDNEREEKPTV 180
KTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLSAKEGDEDEDNEREEKPTV
Sbjct: 121 KTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLSAKEGDEDEDNEREEKPTV 180
Query: 181 EAKVAAERKTPPAPMAPAKKIVPSASEAPAPVVPVDATTSTQMLGSASVDSIE 233
EAKVAAERKTPPAPMAPAKKIVPSASEAPAPVVPVDATTSTQMLGSASVDSIE
Sbjct: 181 EAKVAAERKTPPAPMAPAKKIVPSASEAPAPVVPVDATTSTQMLGSASVDSIE 233
>gi|21264330 mindbomb homolog 2 [Homo sapiens]
Length = 1013
Score = 73.9 bits (180), Expect = 1e-13
Identities = 45/115 (39%), Positives = 66/115 (57%), Gaps = 5/115 (4%)
Query: 28 NEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEG 87
N A LDLL+ + P VD ++ QGRTA+ +AA G + ++ +L Q ++P+DEG
Sbjct: 502 NAARALDLLR----RRPEQVDTKN-QGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEG 556
Query: 88 NTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSR 142
NTALH+AAL N+ A LL+ G RA N TAL + ++ + E+ L R
Sbjct: 557 NTALHYAALGNQPEATRVLLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCER 611
Score = 45.4 bits (106), Expect = 4e-05
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 19 DAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGH-MPILEMLFQFN 77
D L SA G +++ E DV A + QG T +H A+ GH + + ++L +
Sbjct: 623 DTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARAR 682
Query: 78 PQPNVPNDEGNTALHFAALNNRVAAAEALLAHG 110
+ ++G TALH AALNN A+ L+ G
Sbjct: 683 QLVDAKKEDGFTALHLAALNNHREVAQILIREG 715
Score = 41.2 bits (95), Expect = 8e-04
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 1/85 (1%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLF-QFNPQPNVPNDEGNTALHFAALNNRVAAAEA 105
VDA+ E G TA+H+AA N H + ++L + NV N + + LH A V
Sbjct: 685 VDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPL 744
Query: 106 LLAHGWRAAEQNIMGKTALQLIYEK 130
L+ G ++ G TAL + ++
Sbjct: 745 LVDAGCSVNAEDEEGDTALHVALQR 769
Score = 36.6 bits (83), Expect = 0.019
Identities = 22/80 (27%), Positives = 36/80 (45%), Gaps = 1/80 (1%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G ++L++ L+ + VD D++G TA+H AA +L + + N +TA
Sbjct: 534 GQVELIRLLLQAR-AGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCRADAINSTQSTA 592
Query: 91 LHFAALNNRVAAAEALLAHG 110
LH A + AL G
Sbjct: 593 LHVAVQRGFLEVVRALCERG 612
Score = 35.8 bits (81), Expect = 0.032
Identities = 15/61 (24%), Positives = 34/61 (55%)
Query: 34 DLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHF 93
++ + + + DV+ R+ + ++ +H+A H+ ++ +L N ++EG+TALH
Sbjct: 706 EVAQILIREGRCDVNVRNRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHV 765
Query: 94 A 94
A
Sbjct: 766 A 766
Score = 28.9 bits (63), Expect = 3.9
Identities = 14/47 (29%), Positives = 24/47 (51%)
Query: 48 DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFA 94
DA + TA+H+A G + ++ L + N+P+ +T LH A
Sbjct: 583 DAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLPDAHSDTPLHSA 629
>gi|30348954 mindbomb homolog 1 [Homo sapiens]
Length = 1006
Score = 63.5 bits (153), Expect = 1e-10
Identities = 46/138 (33%), Positives = 70/138 (50%), Gaps = 18/138 (13%)
Query: 34 DLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPN---DEGNTA 90
D+L LE +DV + G A+H AA G+ + +L P+P + + D+G TA
Sbjct: 577 DILAVLLEAG-ADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTA 635
Query: 91 LHFAALNNRVAAAEALLAHGWRAAE-QNIMGKTALQLIYEKQYNEMETLLMSRDETLDTY 149
LH AALNN V AE L+ G + QN+ +TAL L E+Q+ ++ LL+
Sbjct: 636 LHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLV--------- 686
Query: 150 VPPTQASVMVDLSAKEGD 167
+A +D+ K+GD
Sbjct: 687 ----RAGAKLDIQDKDGD 700
Score = 51.6 bits (122), Expect = 6e-07
Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 1/113 (0%)
Query: 28 NEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEG 87
++ G +D+LK L++N DV+A D+ G AVH AA ++E+L + + N N
Sbjct: 472 SQNGHVDILKLLLKQNV-DVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRR 530
Query: 88 NTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
T LH A + + LL G + Q+ G T L K+ +++ +L+
Sbjct: 531 QTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLL 583
Score = 49.3 bits (116), Expect = 3e-06
Identities = 28/94 (29%), Positives = 47/94 (50%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD + L + +D++AR+++ +T +H+A GH+ +++ L F P++ + EG+T
Sbjct: 507 GDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTP 566
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
LH A R LL G N G AL
Sbjct: 567 LHDAISKKRDDILAVLLEAGADVTITNNNGFNAL 600
Score = 43.9 bits (102), Expect = 1e-04
Identities = 30/97 (30%), Positives = 45/97 (46%), Gaps = 3/97 (3%)
Query: 31 GDLDLLKAYLEKNPSD--VDARDEQGRTAVHMAAANGHMPILEMLF-QFNPQPNVPNDEG 87
G+ ++ L K P VD + + G TA+H+AA N H+ + E+L Q N ++ N
Sbjct: 607 GNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQ 666
Query: 88 NTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
TALH A L+ G + Q+ G T L
Sbjct: 667 QTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPL 703
Score = 43.1 bits (100), Expect = 2e-04
Identities = 39/125 (31%), Positives = 61/125 (48%), Gaps = 15/125 (12%)
Query: 29 EAGDL--DLLKAY----------LEKNPSDVDARDE-QGRTAVHMAAANGHMPILEMLFQ 75
E+GDL +L+KA L K P DVD + G TA+ A+ NGH+ IL++L +
Sbjct: 427 ESGDLNEELVKAAANGDVAKVEDLLKRP-DVDVNGQCAGHTAMQAASQNGHVDILKLLLK 485
Query: 76 FNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNE- 134
N + +G+ A+H AA + A E L +N +T L + K + +
Sbjct: 486 QNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQV 545
Query: 135 METLL 139
++TLL
Sbjct: 546 VKTLL 550
Score = 32.3 bits (72), Expect = 0.36
Identities = 14/74 (18%), Positives = 41/74 (55%)
Query: 33 LDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALH 92
+++ + + + +++D ++ +TA+H+A H I+ +L + + ++ + +G+T LH
Sbjct: 645 VEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLH 704
Query: 93 FAALNNRVAAAEAL 106
A ++ ++ L
Sbjct: 705 EALRHHTLSQLRQL 718
>gi|89363047 death-associated protein kinase 1 [Homo sapiens]
Length = 1430
Score = 62.8 bits (151), Expect = 2e-10
Identities = 36/117 (30%), Positives = 59/117 (50%), Gaps = 1/117 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +D LK +L +N +D +D+ G A+H+AA GH + ++L F PN+ + E T
Sbjct: 423 GHVDTLK-FLSENKCPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETP 481
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
LH AA + + A+AL G +N G+T L + Y+++ L L+
Sbjct: 482 LHCAAWHGYYSVAKALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGADLN 538
Score = 51.2 bits (121), Expect = 7e-07
Identities = 31/93 (33%), Positives = 44/93 (47%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VD +D G T +H+A +G+MPI+ L + N ++ N G T LH AA N + L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLL 139
G GKTA L +Q+ + LL
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLL 662
Score = 42.4 bits (98), Expect = 3e-04
Identities = 24/80 (30%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++ +L+ +++ S +D +D+ G AV+ AA +GH+ L+ L + +V + G A
Sbjct: 390 GNIQILQLLIKRG-SRIDVQDKGGSNAVYWAARHGHVDTLKFLSENKCPLDVKDKSGEMA 448
Query: 91 LHFAALNNRVAAAEALLAHG 110
LH AA A+ L + G
Sbjct: 449 LHVAARYGHADVAQLLCSFG 468
Score = 39.3 bits (90), Expect = 0.003
Identities = 29/121 (23%), Positives = 54/121 (44%), Gaps = 13/121 (10%)
Query: 46 DVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEA 105
+V+ ++ +G T + A+A G+ I+E L + N + +G+ ALH A ++ +
Sbjct: 503 NVNIKNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKT 562
Query: 106 LLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLSAKE 165
LL+ G Q+ G T L + +D + V +A+ +D+S K
Sbjct: 563 LLSQGCFVDYQDRHGNTPLH-------------VACKDGNMPIVVALCEANCNLDISNKY 609
Query: 166 G 166
G
Sbjct: 610 G 610
Score = 37.4 bits (85), Expect = 0.011
Identities = 23/87 (26%), Positives = 39/87 (44%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L ++ +D++A D+ G A+H+A M +++ L + + GNT LH A +
Sbjct: 530 LAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGN 589
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQL 126
+ AL N G+T L L
Sbjct: 590 MPIVVALCEANCNLDISNKYGRTPLHL 616
Score = 31.6 bits (70), Expect = 0.61
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++ ++ A E N ++D ++ GRT +H+AA NG + ++ L +G TA
Sbjct: 588 GNMPIVVALCEAN-CNLDISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKTA 646
>gi|20270347 ankyrin repeat domain 54 [Homo sapiens]
Length = 300
Score = 62.8 bits (151), Expect = 2e-10
Identities = 37/101 (36%), Positives = 53/101 (52%), Gaps = 1/101 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
A D++ ++ LE +D A D++GRTA+H A+ NG+ I+++L PN + GNT
Sbjct: 120 ANDVETVQQLLEDG-ADPCAADDKGRTALHFASCNGNDQIVQLLLDHGADPNQRDGLGNT 178
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEK 130
LH AA N V LL G R + G+T L L K
Sbjct: 179 PLHLAACTNHVPVITTLLRGGARVDALDRAGRTPLHLAKSK 219
>gi|62988328 ankyrin repeat domain 50 [Homo sapiens]
Length = 1429
Score = 62.4 bits (150), Expect = 3e-10
Identities = 36/114 (31%), Positives = 60/114 (52%), Gaps = 1/114 (0%)
Query: 28 NEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEG 87
++ G D ++ LE N S++D R GR A+ +AA GH I+E+LF N + +G
Sbjct: 888 SQEGHYDCVQILLE-NKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADG 946
Query: 88 NTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMS 141
L+ AL N++ AE L +G + G+TAL + + + EM +L++
Sbjct: 947 RPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIA 1000
Score = 56.2 bits (134), Expect = 2e-08
Identities = 29/102 (28%), Positives = 56/102 (54%)
Query: 39 YLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNN 98
Y +N ++V+A D +GRTA+H++ GHM ++++L ++ N ++E +AL AA
Sbjct: 964 YFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQG 1023
Query: 99 RVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
V + L+ HG G TAL + ++ + ++ +L+
Sbjct: 1024 HVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLL 1065
Score = 50.8 bits (120), Expect = 1e-06
Identities = 35/106 (33%), Positives = 50/106 (47%), Gaps = 5/106 (4%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VD D RTA+ AA GH I+ L Q + N ++EG TAL AA E L
Sbjct: 637 VDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHL 696
Query: 107 LAHGWRAAEQNIMGKTALQLI-----YEKQYNEMETLLMSRDETLD 147
L HG +++ G+TAL + K + + +LL+ R +D
Sbjct: 697 LDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVD 742
Score = 48.9 bits (115), Expect = 4e-06
Identities = 26/95 (27%), Positives = 52/95 (54%)
Query: 45 SDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAE 104
+DV+A D + R+A+ AA GH+ ++++L + + ++G TAL AA + +
Sbjct: 1003 ADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQ 1062
Query: 105 ALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLL 139
LL HG + G+TA+++ + ++++ LL
Sbjct: 1063 VLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 1097
Score = 47.8 bits (112), Expect = 8e-06
Identities = 28/101 (27%), Positives = 48/101 (47%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VD+ D +GRT + +A+A G++ ++ L N +D G T LH AA EAL
Sbjct: 807 VDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 866
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
+ G R E + G+ L ++ + + +L+ +D
Sbjct: 867 IEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNID 907
Score = 42.7 bits (99), Expect = 3e-04
Identities = 27/111 (24%), Positives = 55/111 (49%), Gaps = 1/111 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++++++ L++ D + RD+ G T +HMAA GH I E L + + N +++G
Sbjct: 825 GNVEVVRTLLDRG-LDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 883
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMS 141
A+ + LL + ++ G+ AL++ + + ++ LL S
Sbjct: 884 FILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFS 934
Score = 42.0 bits (97), Expect = 5e-04
Identities = 28/96 (29%), Positives = 43/96 (44%), Gaps = 1/96 (1%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +D++ LE +DVD D GRT + AA+ GH ++ L + + + EG T
Sbjct: 759 GHVDVVDLLLEGG-ADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTV 817
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQL 126
L A+ V LL G ++ G T L +
Sbjct: 818 LSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHM 853
Score = 40.4 bits (93), Expect = 0.001
Identities = 26/96 (27%), Positives = 44/96 (45%), Gaps = 1/96 (1%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
+G LD++ + + +D++ D G T + +AA GH ++ L N + +G T
Sbjct: 555 SGSLDVVNLLVSRG-ADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWT 613
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQ 125
AL AA ALL G + + +TAL+
Sbjct: 614 ALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALR 649
Score = 40.0 bits (92), Expect = 0.002
Identities = 21/64 (32%), Positives = 33/64 (51%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VD QG TA+ +AA GH+ ++++L + PN + G TA+ AA N + L
Sbjct: 1038 VDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLL 1097
Query: 107 LAHG 110
+G
Sbjct: 1098 EKYG 1101
Score = 38.9 bits (89), Expect = 0.004
Identities = 22/57 (38%), Positives = 33/57 (57%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAAL 96
L ++ ++V+ D +GRTA+ AA GH I+E L + N + +G TAL AAL
Sbjct: 663 LLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAAL 719
Score = 37.0 bits (84), Expect = 0.014
Identities = 24/98 (24%), Positives = 45/98 (45%)
Query: 45 SDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAE 104
++VD D+ G T + +AA GH+ ++++L + + ++ G T L AA +
Sbjct: 739 AEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVN 798
Query: 105 ALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSR 142
LL G + G+T L + + E+ L+ R
Sbjct: 799 TLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDR 836
Score = 35.8 bits (81), Expect = 0.032
Identities = 22/80 (27%), Positives = 37/80 (46%)
Query: 45 SDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAE 104
++++ D+ G TA+ AA GH ++ L + + + + TAL AA
Sbjct: 602 ANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVL 661
Query: 105 ALLAHGWRAAEQNIMGKTAL 124
LL HG + + G+TAL
Sbjct: 662 NLLQHGAEVNKADNEGRTAL 681
Score = 35.8 bits (81), Expect = 0.032
Identities = 17/48 (35%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQF 76
+ G +D+++ LE +D + D+ GRTA+ +AA NGH I+++L ++
Sbjct: 1054 QEGHIDVVQVLLEHG-ADPNHADQFGRTAMRVAAKNGHSQIIKLLEKY 1100
Score = 34.3 bits (77), Expect = 0.094
Identities = 25/90 (27%), Positives = 38/90 (42%)
Query: 35 LLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFA 94
LL E N DVD R A+ + A+ GH ++ +L + + + +G T L A
Sbjct: 696 LLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVA 755
Query: 95 ALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
A V + LL G + G+T L
Sbjct: 756 AYEGHVDVVDLLLEGGADVDHTDNNGRTPL 785
Score = 32.7 bits (73), Expect = 0.27
Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 34 DLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHF 93
D ++ L+ N + V+ D GRT + AA +G + ++ +L + + G+T L
Sbjct: 526 DSIRTLLD-NGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTL 584
Query: 94 AALNNRVAAAEALLAHGWRAAEQNIMGKTALQ 125
AA L+ G + G TAL+
Sbjct: 585 AARQGHTKVVNCLIGCGANINHTDQDGWTALR 616
>gi|34304381 inversin isoform a [Homo sapiens]
Length = 1065
Score = 62.0 bits (149), Expect = 4e-10
Identities = 54/188 (28%), Positives = 94/188 (50%), Gaps = 26/188 (13%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPN--VPNDEGNTALHFAA 95
A L +N +D + +D++GRTA+H + NG++ +++L F PN N+E T L +A
Sbjct: 473 AVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYAL 532
Query: 96 LNNRVAAAEALLAHGWR--AAEQNIMGKTALQLIYE-----KQYNEMETLLMSRDETLDT 148
L R + +L HG AA Q+I +Q +Y+ K + + + LLM ++
Sbjct: 533 LGERHEVIQFMLEHGALSIAAIQDI-AAFKIQAVYKGYKVRKAFRDRKNLLMKHEQ---- 587
Query: 149 YVPPTQASVMVDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPA-PMAPAKKIVPS-AS 206
+ D +AK+ +E+N+R+E + + + + P A P P+ + VPS S
Sbjct: 588 --------LRKDAAAKK--REEENKRKEAEQQKGRRSPDSCRPQALPCLPSTQDVPSRQS 637
Query: 207 EAPAPVVP 214
AP+ P
Sbjct: 638 RAPSKQPP 645
Score = 49.3 bits (116), Expect = 3e-06
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
Query: 33 LDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPND-EGNTAL 91
+D+L +Y N + + D RT +H AA GH I+ +L + N +P+D +G T L
Sbjct: 237 VDVLTSYESCN---ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPL 293
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVP 151
H+AA +N + L H + ++ G+T+ K +++ ++S +D +
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 152 PTQASVMVDLSAKEG 166
+ +A G
Sbjct: 354 DKYGGTALHAAALSG 368
Score = 46.2 bits (108), Expect = 2e-05
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
+G + +K LE N + VDA D T + A GH +++ L + + ++ + +G++
Sbjct: 367 SGHVSTVKLLLENN-AQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHS 425
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
LH+AAL + L+ + Q+ G+T LQ Y +LM +
Sbjct: 426 LLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Score = 45.4 bits (106), Expect = 4e-05
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Query: 16 TDVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQ 75
TDV R E G D+++ + K + VD D+ G + +H AA G+ + ++L +
Sbjct: 386 TDVMKHTPLFRACEMGHKDVIQTLI-KGGARVDLVDQDGHSLLHWAALGGNADVCQILIE 444
Query: 76 FNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEM 135
PNV + G T L AA + L+ + Q+ G+TAL Y +
Sbjct: 445 NKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDA 504
Query: 136 ETLLM 140
LL+
Sbjct: 505 IKLLL 509
Score = 42.7 bits (99), Expect = 3e-04
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 3/116 (2%)
Query: 34 DLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQP--NVPNDEGNTAL 91
+ +K +L K+PS D D +GRT+ AA G +L + N+ + G TAL
Sbjct: 303 ETVKVFL-KHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTAL 361
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AAL+ V+ + LL + + ++M T L E + ++ L+ +D
Sbjct: 362 HAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVD 417
Score = 37.4 bits (85), Expect = 0.011
Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Query: 58 VHMAAANGHMPILEMLFQFNPQPNVPNDE-GNTALHFAALNNRVAAAEALLAHGWRAAEQ 116
VH AA NG L+ L N D+ G T L + L +R+ A+ALL G +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 117 NIMGKTALQLIYEK-QYNEMETLLMSR 142
+ +TAL L +K Y M+ LL R
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRR 104
Score = 36.2 bits (82), Expect = 0.025
Identities = 16/52 (30%), Positives = 31/52 (59%)
Query: 44 PSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAA 95
P +VD +D+ +TA+H +A + +++L + + +P+ EG LH+AA
Sbjct: 139 PGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAA 190
Score = 28.9 bits (63), Expect = 3.9
Identities = 22/96 (22%), Positives = 36/96 (37%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD L+ + N + D D+ GRT + + + L + N + TA
Sbjct: 25 GDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTA 84
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQL 126
LH AA + LL ++++ T L L
Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHL 120
>gi|34304379 inversin isoform b [Homo sapiens]
Length = 895
Score = 62.0 bits (149), Expect = 4e-10
Identities = 54/188 (28%), Positives = 94/188 (50%), Gaps = 26/188 (13%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPN--VPNDEGNTALHFAA 95
A L +N +D + +D++GRTA+H + NG++ +++L F PN N+E T L +A
Sbjct: 473 AVLMENNADPNIQDKEGRTALHWSCNNGYLDAIKLLLDFAAFPNQMENNEERYTPLDYAL 532
Query: 96 LNNRVAAAEALLAHGWR--AAEQNIMGKTALQLIYE-----KQYNEMETLLMSRDETLDT 148
L R + +L HG AA Q+I +Q +Y+ K + + + LLM ++
Sbjct: 533 LGERHEVIQFMLEHGALSIAAIQDI-AAFKIQAVYKGYKVRKAFRDRKNLLMKHEQ---- 587
Query: 149 YVPPTQASVMVDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPA-PMAPAKKIVPS-AS 206
+ D +AK+ +E+N+R+E + + + + P A P P+ + VPS S
Sbjct: 588 --------LRKDAAAKK--REEENKRKEAEQQKGRRSPDSCRPQALPCLPSTQDVPSRQS 637
Query: 207 EAPAPVVP 214
AP+ P
Sbjct: 638 RAPSKQPP 645
Score = 49.3 bits (116), Expect = 3e-06
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
Query: 33 LDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPND-EGNTAL 91
+D+L +Y N + + D RT +H AA GH I+ +L + N +P+D +G T L
Sbjct: 237 VDVLTSYESCN---ITSYDNLFRTPLHWAALLGHAQIVHLLLERNKSGTIPSDSQGATPL 293
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVP 151
H+AA +N + L H + ++ G+T+ K +++ ++S +D +
Sbjct: 294 HYAAQSNFAETVKVFLKHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMA 353
Query: 152 PTQASVMVDLSAKEG 166
+ +A G
Sbjct: 354 DKYGGTALHAAALSG 368
Score = 46.2 bits (108), Expect = 2e-05
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 1/114 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
+G + +K LE N + VDA D T + A GH +++ L + + ++ + +G++
Sbjct: 367 SGHVSTVKLLLENN-AQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVDLVDQDGHS 425
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
LH+AAL + L+ + Q+ G+T LQ Y +LM +
Sbjct: 426 LLHWAALGGNADVCQILIENKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENN 479
Score = 45.4 bits (106), Expect = 4e-05
Identities = 34/125 (27%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Query: 16 TDVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQ 75
TDV R E G D+++ + K + VD D+ G + +H AA G+ + ++L +
Sbjct: 386 TDVMKHTPLFRACEMGHKDVIQTLI-KGGARVDLVDQDGHSLLHWAALGGNADVCQILIE 444
Query: 76 FNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEM 135
PNV + G T L AA + L+ + Q+ G+TAL Y +
Sbjct: 445 NKINPNVQDYAGRTPLQCAAYGGYINCMAVLMENNADPNIQDKEGRTALHWSCNNGYLDA 504
Query: 136 ETLLM 140
LL+
Sbjct: 505 IKLLL 509
Score = 42.7 bits (99), Expect = 3e-04
Identities = 32/116 (27%), Positives = 54/116 (46%), Gaps = 3/116 (2%)
Query: 34 DLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQP--NVPNDEGNTAL 91
+ +K +L K+PS D D +GRT+ AA G +L + N+ + G TAL
Sbjct: 303 ETVKVFL-KHPSVKDDSDLEGRTSFMWAAGKGSDDVLRTMLSLKSDIDINMADKYGGTAL 361
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AAL+ V+ + LL + + ++M T L E + ++ L+ +D
Sbjct: 362 HAAALSGHVSTVKLLLENNAQVDATDVMKHTPLFRACEMGHKDVIQTLIKGGARVD 417
Score = 37.4 bits (85), Expect = 0.011
Identities = 30/87 (34%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Query: 58 VHMAAANGHMPILEMLFQFNPQPNVPNDE-GNTALHFAALNNRVAAAEALLAHGWRAAEQ 116
VH AA NG L+ L N D+ G T L + L +R+ A+ALL G +
Sbjct: 18 VHAAAVNGDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKT 77
Query: 117 NIMGKTALQLIYEK-QYNEMETLLMSR 142
+ +TAL L +K Y M+ LL R
Sbjct: 78 DHSQRTALHLAAQKGNYRFMKLLLTRR 104
Score = 36.2 bits (82), Expect = 0.025
Identities = 16/52 (30%), Positives = 31/52 (59%)
Query: 44 PSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAA 95
P +VD +D+ +TA+H +A + +++L + + +P+ EG LH+AA
Sbjct: 139 PGEVDTQDKNKQTALHWSAYYNNPEHVKLLIKHDSNIGIPDVEGKIPLHWAA 190
Score = 28.9 bits (63), Expect = 3.9
Identities = 22/96 (22%), Positives = 36/96 (37%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD L+ + N + D D+ GRT + + + L + N + TA
Sbjct: 25 GDKGALQRLIVGNSALKDKEDQFGRTPLMYCVLADRLDCADALLKAGADVNKTDHSQRTA 84
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQL 126
LH AA + LL ++++ T L L
Sbjct: 85 LHLAAQKGNYRFMKLLLTRRANWMQKDLEEMTPLHL 120
>gi|194018403 ankyrin repeat domain 2 isoform b [Homo sapiens]
Length = 327
Score = 61.2 bits (147), Expect = 7e-10
Identities = 34/97 (35%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +++L+ L+ N + VD +D TA+H A GH+ ++++L NV + EG+TA
Sbjct: 192 GHMEILEKLLD-NGATVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKEGDTA 250
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLI 127
LH A NR + LL HG +N+ GKT L+
Sbjct: 251 LHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTPTDLV 287
Score = 29.6 bits (65), Expect = 2.3
Identities = 27/108 (25%), Positives = 40/108 (37%)
Query: 34 DLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHF 93
D L A E P + AA G M ++E + + TALH
Sbjct: 128 DALAASHEPPPEPEEITGPVDEETFLKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHR 187
Query: 94 AALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMS 141
A+L + E LL +G Q+ + TA+ + E+ LL S
Sbjct: 188 ASLEGHMEILEKLLDNGATVDFQDRLDCTAMHWACRGGHLEVVKLLQS 235
>gi|50511945 cajalin 2 isoform a [Homo sapiens]
Length = 1248
Score = 60.8 bits (146), Expect = 9e-10
Identities = 40/124 (32%), Positives = 60/124 (48%), Gaps = 5/124 (4%)
Query: 46 DVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEA 105
+V+ D G TA+H AA NGH I+ L Q+ NV +++G +H AA V +
Sbjct: 51 NVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADNKGYFPIHLAAWKGDVEIVKI 110
Query: 106 LLAHG---WRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLS 162
L+ HG R EQN +TAL QY E + + +E D + ++ +DL+
Sbjct: 111 LIHHGPSHSRVNEQNNENETALHC--AAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLA 168
Query: 163 AKEG 166
A G
Sbjct: 169 ALYG 172
Score = 45.8 bits (107), Expect = 3e-05
Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 2/99 (2%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G L ++K + +P+ + + T +H+AA NGH ++++L + + ++G+ A
Sbjct: 172 GRLRVVKMIISAHPNLMSCNTRK-HTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGS-A 229
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYE 129
LH AAL +V LL G A ++ +G+T L ++ E
Sbjct: 230 LHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKE 268
Score = 44.3 bits (103), Expect = 9e-05
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 2/112 (1%)
Query: 31 GDLDLLKAYLEKNPSD--VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
GD++++K + PS V+ ++ + TA+H AA GH ++ +L + P + N +
Sbjct: 103 GDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLE 162
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
T L AAL R+ + +++ N T L L + + +L+
Sbjct: 163 TPLDLAALYGRLRVVKMIISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLL 214
>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
Length = 1897
Score = 58.9 bits (141), Expect = 4e-09
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Query: 24 SARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVP 83
+A+Y + +LL LE++ + +A + G T +H+A + ++ I+++L P+ P
Sbjct: 576 AAKYGKVRVAELL---LERD-AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 631
Query: 84 NDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSR 142
G T LH AA N+V A +LL +G A +++ G T L L ++ + EM LL+S+
Sbjct: 632 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 690
Score = 53.5 bits (127), Expect = 1e-07
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L K + +DA E G T +H+A+ GH+PI++ L Q PNV N + T LH AA
Sbjct: 423 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 482
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMV 159
A+ LL + + + +T L + M LL+ + + + T +
Sbjct: 483 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--ENNANPNLATTAGHTPL 540
Query: 160 DLSAKEGDEDEDNEREEKPTVEAKVAAERKTP 191
++A+EG + EK +A + + TP
Sbjct: 541 HIAAREGHVETVLALLEKEASQACMTKKGFTP 572
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
AG ++ K YL +N + V+A+ + +T +H AA GH ++++L + N PN+ G+T
Sbjct: 480 AGHTEVAK-YLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHT 538
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
LH AA V ALL A G T L + + + LL+ RD
Sbjct: 539 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 592
Score = 48.1 bits (113), Expect = 6e-06
Identities = 33/129 (25%), Positives = 59/129 (45%), Gaps = 1/129 (0%)
Query: 12 REPLTDVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILE 71
R+ DA R +G+LD +L +N D++ ++ G +H+A+ GH+ ++
Sbjct: 37 RDRKKKADAATSFLRAARSGNLDKALDHL-RNGVDINTCNQNGLNGLHLASKEGHVKMVV 95
Query: 72 MLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQ 131
L +GNTALH AAL + L+ +G Q+ G T L + ++
Sbjct: 96 ELLHKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQEN 155
Query: 132 YNEMETLLM 140
+ E+ L+
Sbjct: 156 HLEVVKFLL 164
Score = 47.8 bits (112), Expect = 8e-06
Identities = 26/79 (32%), Positives = 36/79 (45%)
Query: 48 DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALL 107
+A QG T +H+AA GH ++ +L N+ N G T LH A V A+ L+
Sbjct: 662 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 721
Query: 108 AHGWRAAEQNIMGKTALQL 126
HG MG T L +
Sbjct: 722 KHGVMVDATTRMGYTPLHV 740
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/174 (22%), Positives = 79/174 (45%), Gaps = 21/174 (12%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++ L+K +L ++ +DV+A+ + G + +H AA GH I+ +L + PN + +G T
Sbjct: 745 GNIKLVK-FLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTP 803
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEK-QYNEMETLLMSRDETLDTY 149
L A ++ + L + + +T+ L+ +K + + ET+ DE LD
Sbjct: 804 LAIAKRLGYISVTDVL---------KVVTDETSFVLVSDKHRMSFPETV----DEILDVS 850
Query: 150 VPPTQASV------MVDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPAPMAP 197
A + ++ A+ D + +E +E K+ ++P P P
Sbjct: 851 EDEGTAHITIMGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIP 904
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/101 (24%), Positives = 49/101 (48%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
+ A+ + G + +HMAA H+ + +L Q++ + + + T LH AA A+ L
Sbjct: 331 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 390
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
L G + + + G T L + +K + + LL+ ++D
Sbjct: 391 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 431
Score = 41.6 bits (96), Expect = 6e-04
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +++K LE N ++ + G T +H+AA GH+ + L + +G T
Sbjct: 514 GHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTP 572
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
LH AA +V AE LL R A N GK L
Sbjct: 573 LHVAAKYGKVRVAELLLE---RDAHPNAAGKNGL 603
Score = 41.2 bits (95), Expect = 8e-04
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+L++ + L + S V+ + G T +H+A+ G++ ++ +L Q + T L
Sbjct: 251 NLNVAQLLLNRGAS-VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 309
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA N V +E LL HG + G + + + + + + LL+ D +D
Sbjct: 310 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 365
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
+ G +++ L K + + ++ G T +H+ A GH+P+ ++L + + G
Sbjct: 677 QEGHAEMVALLLSKQANG-NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGY 735
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
T LH A+ + + LL H + +G + L ++ + ++ TLL+
Sbjct: 736 TPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 787
Score = 39.3 bits (90), Expect = 0.003
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 8/128 (6%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VDA G T +H+A+ G++ +++ L Q N G + LH AA L
Sbjct: 727 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 786
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQY-NEMETLLMSRDETLDTYVP-------PTQASVM 158
L +G E + G T L + Y + + L + DET V P +
Sbjct: 787 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSFPETVDEI 846
Query: 159 VDLSAKEG 166
+D+S EG
Sbjct: 847 LDVSEDEG 854
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
++ ++G TA+H+AA G ++ L + N + +G T L+ AA N + + L
Sbjct: 104 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 163
Query: 107 LAHGWRAAEQNI 118
L +G A QN+
Sbjct: 164 LENG---ANQNV 172
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/92 (30%), Positives = 41/92 (44%)
Query: 57 AVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQ 116
A+H+AA N +L Q +P P+V + G T LH AA + A+ LL G
Sbjct: 209 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 268
Query: 117 NIMGKTALQLIYEKQYNEMETLLMSRDETLDT 148
G T L + + M LL+ R ++T
Sbjct: 269 PQNGITPLHIASRRGNVIMVRLLLDRGAQIET 300
Score = 38.1 bits (87), Expect = 0.007
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+LD++K L + S + G T +H+AA + + L Q+ N + +G T L
Sbjct: 614 NLDIVKLLLPRGGSP-HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 672
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA LL+ N G T L L+ ++ + + +L+ +D
Sbjct: 673 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVD 728
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 37 KAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAAL 96
K L+K ++R G T +H+A H+ ++E+L + + + G T LH A+
Sbjct: 388 KVLLDKGAKP-NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASF 446
Query: 97 NNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
+ + LL G N+ +T L + + E+ L+
Sbjct: 447 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 490
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/73 (27%), Positives = 31/73 (42%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
A L +N + D + G T +H+AA ++ + ++L N G T LH A+
Sbjct: 223 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRR 282
Query: 98 NRVAAAEALLAHG 110
V LL G
Sbjct: 283 GNVIMVRLLLDRG 295
>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
Length = 1881
Score = 58.9 bits (141), Expect = 4e-09
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Query: 24 SARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVP 83
+A+Y + +LL LE++ + +A + G T +H+A + ++ I+++L P+ P
Sbjct: 543 AAKYGKVRVAELL---LERD-AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 84 NDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSR 142
G T LH AA N+V A +LL +G A +++ G T L L ++ + EM LL+S+
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 53.5 bits (127), Expect = 1e-07
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L K + +DA E G T +H+A+ GH+PI++ L Q PNV N + T LH AA
Sbjct: 390 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 449
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMV 159
A+ LL + + + +T L + M LL+ + + + T +
Sbjct: 450 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--ENNANPNLATTAGHTPL 507
Query: 160 DLSAKEGDEDEDNEREEKPTVEAKVAAERKTP 191
++A+EG + EK +A + + TP
Sbjct: 508 HIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
AG ++ K YL +N + V+A+ + +T +H AA GH ++++L + N PN+ G+T
Sbjct: 447 AGHTEVAK-YLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHT 505
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
LH AA V ALL A G T L + + + LL+ RD
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Score = 48.5 bits (114), Expect = 5e-06
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Query: 17 DVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQF 76
+ DA R +G+LD +L +N D++ ++ G +H+A+ GH+ ++ L
Sbjct: 9 EADAATSFLRAARSGNLDKALDHL-RNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Query: 77 NPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEME 136
+GNTALH AAL + L+ +G Q+ G T L + ++ + E+
Sbjct: 68 EIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV 127
Query: 137 TLLM 140
L+
Sbjct: 128 KFLL 131
Score = 47.8 bits (112), Expect = 8e-06
Identities = 26/79 (32%), Positives = 36/79 (45%)
Query: 48 DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALL 107
+A QG T +H+AA GH ++ +L N+ N G T LH A V A+ L+
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 108 AHGWRAAEQNIMGKTALQL 126
HG MG T L +
Sbjct: 689 KHGVMVDATTRMGYTPLHV 707
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/168 (23%), Positives = 79/168 (47%), Gaps = 17/168 (10%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++ L+K +L ++ +DV+A+ + G + +H AA GH I+ +L + PN + +G T
Sbjct: 712 GNIKLVK-FLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTP 770
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEK-QYNEMETLLMSRDETLDTY 149
L A ++ + L + + +T+ L+ +K + + ET+ DE LD
Sbjct: 771 LAIAKRLGYISVTDVL---------KVVTDETSFVLVSDKHRMSFPETV----DEILD-- 815
Query: 150 VPPTQASVMVDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPAPMAP 197
V + ++ A+ D + +E +E K+ ++P P P
Sbjct: 816 VSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIP 863
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/101 (24%), Positives = 49/101 (48%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
+ A+ + G + +HMAA H+ + +L Q++ + + + T LH AA A+ L
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 357
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
L G + + + G T L + +K + + LL+ ++D
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/130 (26%), Positives = 54/130 (41%), Gaps = 8/130 (6%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VDA G T +H+A+ G++ +++ L Q N G + LH AA L
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQY-NEMETLLMSRDETLDTYVP-------PTQASVM 158
L +G E + G T L + Y + + L + DET V P +
Sbjct: 754 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSFPETVDEI 813
Query: 159 VDLSAKEGDE 168
+D+S EG+E
Sbjct: 814 LDVSEDEGEE 823
Score = 41.6 bits (96), Expect = 6e-04
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +++K LE N ++ + G T +H+AA GH+ + L + +G T
Sbjct: 481 GHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
LH AA +V AE LL R A N GK L
Sbjct: 540 LHVAAKYGKVRVAELLLE---RDAHPNAAGKNGL 570
Score = 41.2 bits (95), Expect = 8e-04
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+L++ + L + S V+ + G T +H+A+ G++ ++ +L Q + T L
Sbjct: 218 NLNVAQLLLNRGAS-VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA N V +E LL HG + G + + + + + + LL+ D +D
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
+ G +++ L K + + ++ G T +H+ A GH+P+ ++L + + G
Sbjct: 644 QEGHAEMVALLLSKQANG-NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGY 702
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
T LH A+ + + LL H + +G + L ++ + ++ TLL+
Sbjct: 703 TPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
++ ++G TA+H+AA G ++ L + N + +G T L+ AA N + + L
Sbjct: 71 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 107 LAHGWRAAEQNI 118
L +G A QN+
Sbjct: 131 LENG---ANQNV 139
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/92 (30%), Positives = 41/92 (44%)
Query: 57 AVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQ 116
A+H+AA N +L Q +P P+V + G T LH AA + A+ LL G
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 117 NIMGKTALQLIYEKQYNEMETLLMSRDETLDT 148
G T L + + M LL+ R ++T
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIET 267
Score = 38.1 bits (87), Expect = 0.007
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+LD++K L + S + G T +H+AA + + L Q+ N + +G T L
Sbjct: 581 NLDIVKLLLPRGGSP-HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA LL+ N G T L L+ ++ + + +L+ +D
Sbjct: 640 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVD 695
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 37 KAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAAL 96
K L+K ++R G T +H+A H+ ++E+L + + + G T LH A+
Sbjct: 355 KVLLDKGAKP-NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASF 413
Query: 97 NNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
+ + LL G N+ +T L + + E+ L+
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 457
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/73 (27%), Positives = 31/73 (42%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
A L +N + D + G T +H+AA ++ + ++L N G T LH A+
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRR 249
Query: 98 NRVAAAEALLAHG 110
V LL G
Sbjct: 250 GNVIMVRLLLDRG 262
>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
Length = 1880
Score = 58.9 bits (141), Expect = 4e-09
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Query: 24 SARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVP 83
+A+Y + +LL LE++ + +A + G T +H+A + ++ I+++L P+ P
Sbjct: 543 AAKYGKVRVAELL---LERD-AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 84 NDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSR 142
G T LH AA N+V A +LL +G A +++ G T L L ++ + EM LL+S+
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 53.5 bits (127), Expect = 1e-07
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L K + +DA E G T +H+A+ GH+PI++ L Q PNV N + T LH AA
Sbjct: 390 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 449
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMV 159
A+ LL + + + +T L + M LL+ + + + T +
Sbjct: 450 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--ENNANPNLATTAGHTPL 507
Query: 160 DLSAKEGDEDEDNEREEKPTVEAKVAAERKTP 191
++A+EG + EK +A + + TP
Sbjct: 508 HIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
AG ++ K YL +N + V+A+ + +T +H AA GH ++++L + N PN+ G+T
Sbjct: 447 AGHTEVAK-YLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHT 505
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
LH AA V ALL A G T L + + + LL+ RD
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Score = 48.5 bits (114), Expect = 5e-06
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Query: 17 DVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQF 76
+ DA R +G+LD +L +N D++ ++ G +H+A+ GH+ ++ L
Sbjct: 9 EADAATSFLRAARSGNLDKALDHL-RNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Query: 77 NPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEME 136
+GNTALH AAL + L+ +G Q+ G T L + ++ + E+
Sbjct: 68 EIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV 127
Query: 137 TLLM 140
L+
Sbjct: 128 KFLL 131
Score = 47.8 bits (112), Expect = 8e-06
Identities = 26/79 (32%), Positives = 36/79 (45%)
Query: 48 DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALL 107
+A QG T +H+AA GH ++ +L N+ N G T LH A V A+ L+
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 108 AHGWRAAEQNIMGKTALQL 126
HG MG T L +
Sbjct: 689 KHGVMVDATTRMGYTPLHV 707
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/168 (23%), Positives = 79/168 (47%), Gaps = 17/168 (10%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++ L+K +L ++ +DV+A+ + G + +H AA GH I+ +L + PN + +G T
Sbjct: 712 GNIKLVK-FLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTP 770
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEK-QYNEMETLLMSRDETLDTY 149
L A ++ + L + + +T+ L+ +K + + ET+ DE LD
Sbjct: 771 LAIAKRLGYISVTDVL---------KVVTDETSFVLVSDKHRMSFPETV----DEILD-- 815
Query: 150 VPPTQASVMVDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPAPMAP 197
V + ++ A+ D + +E +E K+ ++P P P
Sbjct: 816 VSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIP 863
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/101 (24%), Positives = 49/101 (48%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
+ A+ + G + +HMAA H+ + +L Q++ + + + T LH AA A+ L
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 357
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
L G + + + G T L + +K + + LL+ ++D
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/130 (26%), Positives = 54/130 (41%), Gaps = 8/130 (6%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VDA G T +H+A+ G++ +++ L Q N G + LH AA L
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQY-NEMETLLMSRDETLDTYVP-------PTQASVM 158
L +G E + G T L + Y + + L + DET V P +
Sbjct: 754 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSFPETVDEI 813
Query: 159 VDLSAKEGDE 168
+D+S EG+E
Sbjct: 814 LDVSEDEGEE 823
Score = 41.6 bits (96), Expect = 6e-04
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +++K LE N ++ + G T +H+AA GH+ + L + +G T
Sbjct: 481 GHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
LH AA +V AE LL R A N GK L
Sbjct: 540 LHVAAKYGKVRVAELLLE---RDAHPNAAGKNGL 570
Score = 41.2 bits (95), Expect = 8e-04
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+L++ + L + S V+ + G T +H+A+ G++ ++ +L Q + T L
Sbjct: 218 NLNVAQLLLNRGAS-VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA N V +E LL HG + G + + + + + + LL+ D +D
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
+ G +++ L K + + ++ G T +H+ A GH+P+ ++L + + G
Sbjct: 644 QEGHAEMVALLLSKQANG-NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGY 702
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
T LH A+ + + LL H + +G + L ++ + ++ TLL+
Sbjct: 703 TPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
++ ++G TA+H+AA G ++ L + N + +G T L+ AA N + + L
Sbjct: 71 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 107 LAHGWRAAEQNI 118
L +G A QN+
Sbjct: 131 LENG---ANQNV 139
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/92 (30%), Positives = 41/92 (44%)
Query: 57 AVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQ 116
A+H+AA N +L Q +P P+V + G T LH AA + A+ LL G
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 117 NIMGKTALQLIYEKQYNEMETLLMSRDETLDT 148
G T L + + M LL+ R ++T
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIET 267
Score = 38.1 bits (87), Expect = 0.007
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+LD++K L + S + G T +H+AA + + L Q+ N + +G T L
Sbjct: 581 NLDIVKLLLPRGGSP-HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA LL+ N G T L L+ ++ + + +L+ +D
Sbjct: 640 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVD 695
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 37 KAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAAL 96
K L+K ++R G T +H+A H+ ++E+L + + + G T LH A+
Sbjct: 355 KVLLDKGAKP-NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASF 413
Query: 97 NNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
+ + LL G N+ +T L + + E+ L+
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 457
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/73 (27%), Positives = 31/73 (42%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
A L +N + D + G T +H+AA ++ + ++L N G T LH A+
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRR 249
Query: 98 NRVAAAEALLAHG 110
V LL G
Sbjct: 250 GNVIMVRLLLDRG 262
>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
Length = 1719
Score = 58.9 bits (141), Expect = 4e-09
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Query: 24 SARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVP 83
+A+Y + +LL LE++ + +A + G T +H+A + ++ I+++L P+ P
Sbjct: 543 AAKYGKVRVAELL---LERD-AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 84 NDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSR 142
G T LH AA N+V A +LL +G A +++ G T L L ++ + EM LL+S+
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 53.5 bits (127), Expect = 1e-07
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L K + +DA E G T +H+A+ GH+PI++ L Q PNV N + T LH AA
Sbjct: 390 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 449
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMV 159
A+ LL + + + +T L + M LL+ + + + T +
Sbjct: 450 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--ENNANPNLATTAGHTPL 507
Query: 160 DLSAKEGDEDEDNEREEKPTVEAKVAAERKTP 191
++A+EG + EK +A + + TP
Sbjct: 508 HIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
AG ++ K YL +N + V+A+ + +T +H AA GH ++++L + N PN+ G+T
Sbjct: 447 AGHTEVAK-YLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHT 505
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
LH AA V ALL A G T L + + + LL+ RD
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Score = 48.5 bits (114), Expect = 5e-06
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Query: 17 DVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQF 76
+ DA R +G+LD +L +N D++ ++ G +H+A+ GH+ ++ L
Sbjct: 9 EADAATSFLRAARSGNLDKALDHL-RNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Query: 77 NPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEME 136
+GNTALH AAL + L+ +G Q+ G T L + ++ + E+
Sbjct: 68 EIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV 127
Query: 137 TLLM 140
L+
Sbjct: 128 KFLL 131
Score = 47.8 bits (112), Expect = 8e-06
Identities = 26/79 (32%), Positives = 36/79 (45%)
Query: 48 DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALL 107
+A QG T +H+AA GH ++ +L N+ N G T LH A V A+ L+
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 108 AHGWRAAEQNIMGKTALQL 126
HG MG T L +
Sbjct: 689 KHGVMVDATTRMGYTPLHV 707
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/168 (23%), Positives = 79/168 (47%), Gaps = 17/168 (10%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++ L+K +L ++ +DV+A+ + G + +H AA GH I+ +L + PN + +G T
Sbjct: 712 GNIKLVK-FLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTP 770
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEK-QYNEMETLLMSRDETLDTY 149
L A ++ + L + + +T+ L+ +K + + ET+ DE LD
Sbjct: 771 LAIAKRLGYISVTDVL---------KVVTDETSFVLVSDKHRMSFPETV----DEILD-- 815
Query: 150 VPPTQASVMVDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPAPMAP 197
V + ++ A+ D + +E +E K+ ++P P P
Sbjct: 816 VSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIP 863
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/101 (24%), Positives = 49/101 (48%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
+ A+ + G + +HMAA H+ + +L Q++ + + + T LH AA A+ L
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 357
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
L G + + + G T L + +K + + LL+ ++D
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/130 (26%), Positives = 54/130 (41%), Gaps = 8/130 (6%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VDA G T +H+A+ G++ +++ L Q N G + LH AA L
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQY-NEMETLLMSRDETLDTYVP-------PTQASVM 158
L +G E + G T L + Y + + L + DET V P +
Sbjct: 754 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSFPETVDEI 813
Query: 159 VDLSAKEGDE 168
+D+S EG+E
Sbjct: 814 LDVSEDEGEE 823
Score = 41.6 bits (96), Expect = 6e-04
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +++K LE N ++ + G T +H+AA GH+ + L + +G T
Sbjct: 481 GHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
LH AA +V AE LL R A N GK L
Sbjct: 540 LHVAAKYGKVRVAELLLE---RDAHPNAAGKNGL 570
Score = 41.2 bits (95), Expect = 8e-04
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+L++ + L + S V+ + G T +H+A+ G++ ++ +L Q + T L
Sbjct: 218 NLNVAQLLLNRGAS-VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA N V +E LL HG + G + + + + + + LL+ D +D
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
+ G +++ L K + + ++ G T +H+ A GH+P+ ++L + + G
Sbjct: 644 QEGHAEMVALLLSKQANG-NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGY 702
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
T LH A+ + + LL H + +G + L ++ + ++ TLL+
Sbjct: 703 TPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
++ ++G TA+H+AA G ++ L + N + +G T L+ AA N + + L
Sbjct: 71 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 107 LAHGWRAAEQNI 118
L +G A QN+
Sbjct: 131 LENG---ANQNV 139
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/92 (30%), Positives = 41/92 (44%)
Query: 57 AVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQ 116
A+H+AA N +L Q +P P+V + G T LH AA + A+ LL G
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 117 NIMGKTALQLIYEKQYNEMETLLMSRDETLDT 148
G T L + + M LL+ R ++T
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIET 267
Score = 38.1 bits (87), Expect = 0.007
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+LD++K L + S + G T +H+AA + + L Q+ N + +G T L
Sbjct: 581 NLDIVKLLLPRGGSP-HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA LL+ N G T L L+ ++ + + +L+ +D
Sbjct: 640 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVD 695
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 37 KAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAAL 96
K L+K ++R G T +H+A H+ ++E+L + + + G T LH A+
Sbjct: 355 KVLLDKGAKP-NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASF 413
Query: 97 NNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
+ + LL G N+ +T L + + E+ L+
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 457
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/73 (27%), Positives = 31/73 (42%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
A L +N + D + G T +H+AA ++ + ++L N G T LH A+
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRR 249
Query: 98 NRVAAAEALLAHG 110
V LL G
Sbjct: 250 GNVIMVRLLLDRG 262
>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
Length = 1856
Score = 58.9 bits (141), Expect = 4e-09
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Query: 24 SARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVP 83
+A+Y + +LL LE++ + +A + G T +H+A + ++ I+++L P+ P
Sbjct: 543 AAKYGKVRVAELL---LERD-AHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGSPHSP 598
Query: 84 NDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSR 142
G T LH AA N+V A +LL +G A +++ G T L L ++ + EM LL+S+
Sbjct: 599 AWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVALLLSK 657
Score = 53.5 bits (127), Expect = 1e-07
Identities = 41/152 (26%), Positives = 68/152 (44%), Gaps = 2/152 (1%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L K + +DA E G T +H+A+ GH+PI++ L Q PNV N + T LH AA
Sbjct: 390 LLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGH 449
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMV 159
A+ LL + + + +T L + M LL+ + + + T +
Sbjct: 450 TEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLL--ENNANPNLATTAGHTPL 507
Query: 160 DLSAKEGDEDEDNEREEKPTVEAKVAAERKTP 191
++A+EG + EK +A + + TP
Sbjct: 508 HIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/114 (31%), Positives = 56/114 (49%), Gaps = 1/114 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
AG ++ K YL +N + V+A+ + +T +H AA GH ++++L + N PN+ G+T
Sbjct: 447 AGHTEVAK-YLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHT 505
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
LH AA V ALL A G T L + + + LL+ RD
Sbjct: 506 PLHIAAREGHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERD 559
Score = 48.5 bits (114), Expect = 5e-06
Identities = 32/124 (25%), Positives = 58/124 (46%), Gaps = 1/124 (0%)
Query: 17 DVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQF 76
+ DA R +G+LD +L +N D++ ++ G +H+A+ GH+ ++ L
Sbjct: 9 EADAATSFLRAARSGNLDKALDHL-RNGVDINTCNQNGLNGLHLASKEGHVKMVVELLHK 67
Query: 77 NPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEME 136
+GNTALH AAL + L+ +G Q+ G T L + ++ + E+
Sbjct: 68 EIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVV 127
Query: 137 TLLM 140
L+
Sbjct: 128 KFLL 131
Score = 47.8 bits (112), Expect = 8e-06
Identities = 26/79 (32%), Positives = 36/79 (45%)
Query: 48 DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALL 107
+A QG T +H+AA GH ++ +L N+ N G T LH A V A+ L+
Sbjct: 629 NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLI 688
Query: 108 AHGWRAAEQNIMGKTALQL 126
HG MG T L +
Sbjct: 689 KHGVMVDATTRMGYTPLHV 707
Score = 47.0 bits (110), Expect = 1e-05
Identities = 40/168 (23%), Positives = 79/168 (47%), Gaps = 17/168 (10%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G++ L+K +L ++ +DV+A+ + G + +H AA GH I+ +L + PN + +G T
Sbjct: 712 GNIKLVK-FLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLLKNGASPNEVSSDGTTP 770
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEK-QYNEMETLLMSRDETLDTY 149
L A ++ + L + + +T+ L+ +K + + ET+ DE LD
Sbjct: 771 LAIAKRLGYISVTDVL---------KVVTDETSFVLVSDKHRMSFPETV----DEILD-- 815
Query: 150 VPPTQASVMVDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPAPMAP 197
V + ++ A+ D + +E +E K+ ++P P P
Sbjct: 816 VSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIP 863
Score = 42.4 bits (98), Expect = 3e-04
Identities = 25/101 (24%), Positives = 49/101 (48%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
+ A+ + G + +HMAA H+ + +L Q++ + + + T LH AA A+ L
Sbjct: 298 IQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVL 357
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
L G + + + G T L + +K + + LL+ ++D
Sbjct: 358 LDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLKTGASID 398
Score = 42.0 bits (97), Expect = 5e-04
Identities = 35/130 (26%), Positives = 54/130 (41%), Gaps = 8/130 (6%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VDA G T +H+A+ G++ +++ L Q N G + LH AA L
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQY-NEMETLLMSRDETLDTYVP-------PTQASVM 158
L +G E + G T L + Y + + L + DET V P +
Sbjct: 754 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRMSFPETVDEI 813
Query: 159 VDLSAKEGDE 168
+D+S EG+E
Sbjct: 814 LDVSEDEGEE 823
Score = 41.6 bits (96), Expect = 6e-04
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G +++K LE N ++ + G T +H+AA GH+ + L + +G T
Sbjct: 481 GHTNMVKLLLENN-ANPNLATTAGHTPLHIAAREGHVETVLALLEKEASQACMTKKGFTP 539
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
LH AA +V AE LL R A N GK L
Sbjct: 540 LHVAAKYGKVRVAELLLE---RDAHPNAAGKNGL 570
Score = 41.2 bits (95), Expect = 8e-04
Identities = 28/116 (24%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+L++ + L + S V+ + G T +H+A+ G++ ++ +L Q + T L
Sbjct: 218 NLNVAQLLLNRGAS-VNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTPL 276
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA N V +E LL HG + G + + + + + + LL+ D +D
Sbjct: 277 HCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/112 (21%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
+ G +++ L K + + ++ G T +H+ A GH+P+ ++L + + G
Sbjct: 644 QEGHAEMVALLLSKQANG-NLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGY 702
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
T LH A+ + + LL H + +G + L ++ + ++ TLL+
Sbjct: 703 TPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLLL 754
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
++ ++G TA+H+AA G ++ L + N + +G T L+ AA N + + L
Sbjct: 71 LETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFL 130
Query: 107 LAHGWRAAEQNI 118
L +G A QN+
Sbjct: 131 LENG---ANQNV 139
Score = 38.5 bits (88), Expect = 0.005
Identities = 28/92 (30%), Positives = 41/92 (44%)
Query: 57 AVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQ 116
A+H+AA N +L Q +P P+V + G T LH AA + A+ LL G
Sbjct: 176 ALHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFT 235
Query: 117 NIMGKTALQLIYEKQYNEMETLLMSRDETLDT 148
G T L + + M LL+ R ++T
Sbjct: 236 PQNGITPLHIASRRGNVIMVRLLLDRGAQIET 267
Score = 38.1 bits (87), Expect = 0.007
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 1/116 (0%)
Query: 32 DLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTAL 91
+LD++K L + S + G T +H+AA + + L Q+ N + +G T L
Sbjct: 581 NLDIVKLLLPRGGSP-HSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSANAESVQGVTPL 639
Query: 92 HFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
H AA LL+ N G T L L+ ++ + + +L+ +D
Sbjct: 640 HLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVD 695
Score = 37.7 bits (86), Expect = 0.008
Identities = 24/104 (23%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 37 KAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAAL 96
K L+K ++R G T +H+A H+ ++E+L + + + G T LH A+
Sbjct: 355 KVLLDKGAKP-NSRALNGFTPLHIACKKNHVRVMELLLKTGASIDAVTESGLTPLHVASF 413
Query: 97 NNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
+ + LL G N+ +T L + + E+ L+
Sbjct: 414 MGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLL 457
Score = 32.7 bits (73), Expect = 0.27
Identities = 20/73 (27%), Positives = 31/73 (42%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
A L +N + D + G T +H+AA ++ + ++L N G T LH A+
Sbjct: 190 AVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRR 249
Query: 98 NRVAAAEALLAHG 110
V LL G
Sbjct: 250 GNVIMVRLLLDRG 262
>gi|13376842 tankyrase, TRF1-interacting ankyrin-related ADP-ribose
polymerase 2 [Homo sapiens]
Length = 1166
Score = 58.9 bits (141), Expect = 4e-09
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 15/158 (9%)
Query: 39 YLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNN 98
YL +N ++V ARD+ G +H A + GH ++ +L + PN ++ T LH AA+
Sbjct: 76 YLLQNGANVQARDDGGLIPLHNACSFGHAEVVNLLLRHGADPNARDNWNYTPLHEAAIKG 135
Query: 99 RVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVM 158
++ LL HG +N G+TAL L + + T +DE L+
Sbjct: 136 KIDVCIVLLQHGAEPTIRNTDGRTALDLA-DPSAKAVLTGEYKKDELLE----------- 183
Query: 159 VDLSAKEGDEDEDNEREEKPTVEAKVAAERKTPPAPMA 196
SA+ G+E++ V + RK+ P +A
Sbjct: 184 ---SARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLA 218
Score = 57.0 bits (136), Expect = 1e-08
Identities = 35/113 (30%), Positives = 54/113 (47%)
Query: 39 YLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNN 98
YL ++ +DV+A+D+ G +H AA+ GH+ + +L ++N N + T LH AA
Sbjct: 697 YLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNATDKWAFTPLHEAAQKG 756
Query: 99 RVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVP 151
R LLAHG +N G+T L L+ + + T M Y P
Sbjct: 757 RTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAMPPSALPSCYKP 809
Score = 50.1 bits (118), Expect = 2e-06
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 5/124 (4%)
Query: 24 SARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVP 83
+A YN ++ YL ++ +DV A+D+ G +H A + GH + E+L + NV
Sbjct: 533 AAGYNRVSVVE----YLLQHGADVHAKDKGGLVPLHNACSYGHYEVAELLVKHGAVVNVA 588
Query: 84 NDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
+ T LH AA + + LL HG ++N G T L L+ + +++ LL
Sbjct: 589 DLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRDGNTPLDLVKDGD-TDIQDLLRGDA 647
Query: 144 ETLD 147
LD
Sbjct: 648 ALLD 651
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 4/111 (3%)
Query: 24 SARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVP 83
+A YN + LL ++ +DV A+D+ +H A + GH + E+L + N
Sbjct: 218 AAGYNRVKIVQLLL----QHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAM 273
Query: 84 NDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNE 134
+ T LH AA NRV LL++G N K+A+ L Q E
Sbjct: 274 DLWQFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTPQLKE 324
Score = 40.0 bits (92), Expect = 0.002
Identities = 21/87 (24%), Positives = 47/87 (54%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L + ++++ + ++ T +H+A+ H ++E++ + + N ++ G T+LH AA
Sbjct: 386 LLRKGANINEKTKEFLTPLHVASEKAHNDVVEVVVKHEAKVNALDNLGQTSLHRAAYCGH 445
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQL 126
+ LL++G ++ G TALQ+
Sbjct: 446 LQTCRLLLSYGCDPNIISLQGFTALQM 472
Score = 38.5 bits (88), Expect = 0.005
Identities = 19/56 (33%), Positives = 31/56 (55%)
Query: 42 KNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
K+ + V+A D G+T++H AA GH+ +L + PN+ + +G TAL N
Sbjct: 421 KHEAKVNALDNLGQTSLHRAAYCGHLQTCRLLLSYGCDPNIISLQGFTALQMGNEN 476
Score = 37.7 bits (86), Expect = 0.008
Identities = 38/143 (26%), Positives = 58/143 (40%), Gaps = 7/143 (4%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGR--TAVHMAAANGHMPILEMLFQFNPQPNVPNDE 86
+AGD++ +K V+ RD +GR T +H AA + ++E L Q + +
Sbjct: 501 KAGDVETVKKLC--TVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKG 558
Query: 87 GNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETL 146
G LH A AE L+ HG ++ T L K E+ LL+
Sbjct: 559 GLVPLHNACSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHG--A 616
Query: 147 DTYVPPTQASVMVDLSAKEGDED 169
D + +DL K+GD D
Sbjct: 617 DPTKKNRDGNTPLDL-VKDGDTD 638
Score = 36.2 bits (82), Expect = 0.025
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 3/123 (2%)
Query: 19 DAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNP 78
D L+SAR +G+ + + A L + A D + T +H+AA + I+++L Q
Sbjct: 179 DELLESAR---SGNEEKMMALLTPLNVNCHASDGRKSTPLHLAAGYNRVKIVQLLLQHGA 235
Query: 79 QPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETL 138
+ + LH A E L+ HG ++ T L K E+ +L
Sbjct: 236 DVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLWQFTPLHEAASKNRVEVCSL 295
Query: 139 LMS 141
L+S
Sbjct: 296 LLS 298
Score = 32.3 bits (72), Expect = 0.36
Identities = 20/70 (28%), Positives = 31/70 (44%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
A L K + V+A D+ T +H AA G + +L P + N EG T L + +
Sbjct: 729 ALLIKYNACVNATDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSAD 788
Query: 98 NRVAAAEALL 107
+ A A +
Sbjct: 789 DVSALLTAAM 798
>gi|96975023 ankyrin repeat and death domain containing 1A [Homo
sapiens]
Length = 522
Score = 58.5 bits (140), Expect = 5e-09
Identities = 45/135 (33%), Positives = 66/135 (48%), Gaps = 6/135 (4%)
Query: 38 AYLEKNPSDV--DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAA 95
A++ ++ DV D D+ GRTA H AA +G + L+ L NV + EGNTALH AA
Sbjct: 141 AFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAA 200
Query: 96 LNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQA 155
+A + L+ G EQN G TAL + + LL+ T++ TQ
Sbjct: 201 GRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNAL---TQK 257
Query: 156 SV-MVDLSAKEGDED 169
++ + +A G ED
Sbjct: 258 NLSCLHYAALSGSED 272
Score = 42.4 bits (98), Expect = 3e-04
Identities = 24/102 (23%), Positives = 48/102 (47%)
Query: 46 DVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEA 105
D++ ++ +G TA+H AA H +++L + N + + LH+AAL+ +
Sbjct: 217 DLEEQNAEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRV 276
Query: 106 LLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
L+ G A + G + L L + + LL++ D ++
Sbjct: 277 LIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVN 318
Score = 38.5 bits (88), Expect = 0.005
Identities = 21/68 (30%), Positives = 37/68 (54%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L + SDV+A D + +T +H+AA + I +ML N+ + +G TAL A +N
Sbjct: 310 LINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAGVDLNLRDKQGKTALAVAVRSNH 369
Query: 100 VAAAEALL 107
V+ + ++
Sbjct: 370 VSLVDMII 377
Score = 36.2 bits (82), Expect = 0.025
Identities = 22/93 (23%), Positives = 42/93 (45%)
Query: 51 DEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHG 110
D QG + +H+A + ++ +L + N ++ T LH AA + A+ LL G
Sbjct: 288 DHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLIAG 347
Query: 111 WRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
++ GKTAL + + + +++ D
Sbjct: 348 VDLNLRDKQGKTALAVAVRSNHVSLVDMIIKAD 380
Score = 36.2 bits (82), Expect = 0.025
Identities = 21/93 (22%), Positives = 48/93 (51%), Gaps = 6/93 (6%)
Query: 46 DVDARDEQGRTAVHMAAANGHMPILEMLFQ----FNPQPNVPNDEGNTALHFAALNNRVA 101
D++ RD+QG+TA+ +A + H+ +++M+ + + + + P+D +L F +
Sbjct: 349 DLNLRDKQGKTALAVAVRSNHVSLVDMIIKADRFYRWEKDHPSDPSGKSLSFK--QDHRQ 406
Query: 102 AAEALLAHGWRAAEQNIMGKTALQLIYEKQYNE 134
+ L + WR A + + + +L Y ++ E
Sbjct: 407 ETQQLRSVLWRLASRYLQPREWKKLAYSWEFTE 439
Score = 31.6 bits (70), Expect = 0.61
Identities = 22/96 (22%), Positives = 42/96 (43%)
Query: 45 SDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAE 104
S V+A ++ + +H AA +G + +L NV + +G + LH A +N A
Sbjct: 249 STVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVR 308
Query: 105 ALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
L+ + +T L L E + ++ +L+
Sbjct: 309 LLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLL 344
Score = 28.5 bits (62), Expect = 5.2
Identities = 26/115 (22%), Positives = 50/115 (43%), Gaps = 4/115 (3%)
Query: 54 GRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRA 113
G A+ ++A GH+ IL++L + + + +G T LH AA V ++
Sbjct: 91 GMNALLLSAWFGHLRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDV 150
Query: 114 AEQNI--MGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLSAKEG 166
A ++ +G+TA E + +++ L D V + + + L+A G
Sbjct: 151 ALDHVDKLGRTAFHRAAE--HGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRG 203
>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 57.8 bits (138), Expect = 8e-09
Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 3/120 (2%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD ++ L + D+DA D+Q RTA+H+A A+GH+ ++ +L Q ++ + E T
Sbjct: 44 GDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTP 103
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQ-LIYEKQYNEMETLLMSRD--ETLD 147
L A A A LL HG ++I G TAL +Y + + E LL + E LD
Sbjct: 104 LIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALD 163
>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
[Homo sapiens]
Length = 823
Score = 57.8 bits (138), Expect = 8e-09
Identities = 40/120 (33%), Positives = 61/120 (50%), Gaps = 3/120 (2%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD ++ L + D+DA D+Q RTA+H+A A+GH+ ++ +L Q ++ + E T
Sbjct: 44 GDAAEMERCLARRSGDLDALDKQHRTALHLACASGHVKVVTLLVNRKCQIDIYDKENRTP 103
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQ-LIYEKQYNEMETLLMSRD--ETLD 147
L A A A LL HG ++I G TAL +Y + + E LL + E LD
Sbjct: 104 LIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLLFHGENIEALD 163
>gi|60460920 ankyrin repeat domain 20 family, member A3 [Homo
sapiens]
Length = 823
Score = 57.4 bits (137), Expect = 1e-08
Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD ++ L + D+DA D+Q RTA+H+A A+GH+ ++ +L Q +V + E T
Sbjct: 44 GDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTP 103
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQ-LIYEKQYNEMETLL 139
L A A A LL HG ++I G TAL +Y + + E LL
Sbjct: 104 LIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLL 153
>gi|60115723 ankyrin repeat domain 20 family, member A2 [Homo
sapiens]
Length = 823
Score = 57.4 bits (137), Expect = 1e-08
Identities = 38/110 (34%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD ++ L + D+DA D+Q RTA+H+A A+GH+ ++ +L Q +V + E T
Sbjct: 44 GDAAEVERCLARRSGDLDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTP 103
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQ-LIYEKQYNEMETLL 139
L A A A LL HG ++I G TAL +Y + + E LL
Sbjct: 104 LIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLL 153
>gi|32967601 ankyrin 3 isoform 1 [Homo sapiens]
Length = 4377
Score = 57.0 bits (136), Expect = 1e-08
Identities = 38/133 (28%), Positives = 69/133 (51%), Gaps = 5/133 (3%)
Query: 9 SEFREPLTDVDA-FLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHM 67
S R+ +D +A +L +AR AG L+ Y+ KN D++ ++ G A+H+A+ GH+
Sbjct: 32 SRDRKKKSDANASYLRAAR---AGHLEKALDYI-KNGVDINICNQNGLNALHLASKEGHV 87
Query: 68 PILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLI 127
++ L Q + +GNTALH A+L + + L+ +G Q+ G T L +
Sbjct: 88 EVVSELLQREANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA 147
Query: 128 YEKQYNEMETLLM 140
++ + E+ L+
Sbjct: 148 AQENHLEVVKFLL 160
Score = 57.0 bits (136), Expect = 1e-08
Identities = 34/94 (36%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 33 LDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALH 92
+D+ LE +D +A QG +VH+AA GH+ ++ +L N N+ N G T LH
Sbjct: 644 MDIATTLLEYG-ADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNANVNLSNKSGLTPLH 702
Query: 93 FAALNNRVAAAEALLAHGWRAAEQNIMGKTALQL 126
AA +RV AE L+ G Q MG T L +
Sbjct: 703 LAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHV 736
Score = 52.8 bits (125), Expect = 3e-07
Identities = 35/130 (26%), Positives = 56/130 (43%), Gaps = 2/130 (1%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L K+ + + A E G T +H+AA GH+ I+ L PN N G TALH AA + +
Sbjct: 419 LLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQ 478
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMV 159
L+ G + + +T L + + + + + + T +
Sbjct: 479 AEVVRYLVQDGAQVEAKAKDDQTPLHI--SARLGKADIVQQLLQQGASPNAATTSGYTPL 536
Query: 160 DLSAKEGDED 169
LSA+EG ED
Sbjct: 537 HLSAREGHED 546
Score = 49.3 bits (116), Expect = 3e-06
Identities = 46/173 (26%), Positives = 72/173 (41%), Gaps = 22/173 (12%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G L++ L+K+ S DA + G T +H+AA + + +L P+ G T
Sbjct: 576 GKLEVANLLLQKSASP-DAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTP 634
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYV 150
LH AA N++ A LL +G A G ++ L ++ + +M +LL+ R+
Sbjct: 635 LHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRNAN----- 689
Query: 151 PPTQASVMVDLSAKEG--------DEDEDNEREEKPTVEAKVAAERKTPPAPM 195
V+LS K G ED N E A V A+ K P+
Sbjct: 690 --------VNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPL 734
Score = 48.5 bits (114), Expect = 5e-06
Identities = 28/116 (24%), Positives = 62/116 (53%), Gaps = 1/116 (0%)
Query: 28 NEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEG 87
++ G ++++ L++ ++VDA ++G TA+H+A+ G ++++L N + G
Sbjct: 82 SKEGHVEVVSELLQRE-ANVDAATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNG 140
Query: 88 NTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
T L+ AA N + + LL +G + G T L + ++ ++++ +LL+ D
Sbjct: 141 FTPLYMAAQENHLEVVKFLLDNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEND 196
Score = 47.4 bits (111), Expect = 1e-05
Identities = 30/109 (27%), Positives = 50/109 (45%)
Query: 39 YLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNN 98
YL ++ + V+A+ + +T +H++A G I++ L Q PN G T LH +A
Sbjct: 484 YLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREG 543
Query: 99 RVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLD 147
A LL HG + G T L + + E+ LL+ + + D
Sbjct: 544 HEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPD 592
Score = 46.6 bits (109), Expect = 2e-05
Identities = 34/128 (26%), Positives = 57/128 (44%), Gaps = 1/128 (0%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
VDA+ + G T +H+ G++ I+ L Q + + N G T LH AA L
Sbjct: 723 VDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 782
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQY-NEMETLLMSRDETLDTYVPPTQASVMVDLSAKE 165
L + E + G TAL + Y + ++TL + +ET+ T + + V + E
Sbjct: 783 LQNNASPNELTVNGNTALGIARRLGYISVVDTLKIVTEETMTTTTVTEKHKMNVPETMNE 842
Query: 166 GDEDEDNE 173
+ D+E
Sbjct: 843 VLDMSDDE 850
Score = 45.4 bits (106), Expect = 4e-05
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 6/134 (4%)
Query: 38 AYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALN 97
A+L + + + ++G T +H+AA G + + +L Q + P+ G T LH AA
Sbjct: 549 AFLLDHGASLSITTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHY 608
Query: 98 NRVAAAEALLAHGW--RAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQA 155
+ A LL G AA +N G T L + +K ++ T L+ + D Q
Sbjct: 609 DNQKVALLLLDQGASPHAAAKN--GYTPLHIAAKKNQMDIATTLL--EYGADANAVTRQG 664
Query: 156 SVMVDLSAKEGDED 169
V L+A+EG D
Sbjct: 665 IASVHLAAQEGHVD 678
Score = 45.4 bits (106), Expect = 4e-05
Identities = 35/132 (26%), Positives = 57/132 (43%), Gaps = 7/132 (5%)
Query: 39 YLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNN 98
+L ++ + V+A+ + G T +H AA GH I+ +L Q N PN GNTAL A
Sbjct: 748 FLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRLG 807
Query: 99 RVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEM--ETLLMSRDETLDTYVPPTQAS 156
++ + L + + M T + ++ E E L MS DE P +
Sbjct: 808 YISVVDTL-----KIVTEETMTTTTVTEKHKMNVPETMNEVLDMSDDEVRKANAPEMLSD 862
Query: 157 VMVDLSAKEGDE 168
+EG++
Sbjct: 863 GEYISDVEEGED 874
Score = 44.3 bits (103), Expect = 9e-05
Identities = 32/139 (23%), Positives = 58/139 (41%), Gaps = 3/139 (2%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G + K L+K ++ +A+ G T +H+A + ++E+L + + G T
Sbjct: 378 GHYKVAKVLLDKK-ANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTP 436
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYV 150
+H AA V L+ HG N+ G+TAL + E+ L+ ++
Sbjct: 437 IHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKA 496
Query: 151 PPTQASVMVDLSAKEGDED 169
Q + +SA+ G D
Sbjct: 497 KDDQTP--LHISARLGKAD 513
Score = 43.9 bits (102), Expect = 1e-04
Identities = 22/55 (40%), Positives = 28/55 (50%)
Query: 56 TAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHG 110
TA+H+AA GH + ++L PN G T LH A NR+ E LL HG
Sbjct: 369 TALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHG 423
Score = 43.5 bits (101), Expect = 2e-04
Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 5/140 (3%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G D+++ L++ S +A G T +H++A GH + L ++ +G T
Sbjct: 510 GKADIVQQLLQQGASP-NAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTP 568
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIY-EKQYNEMETLLMSRDETLDTY 149
LH AA ++ A LL ++A + GK+ L ++ Y+ + L+ D+ +
Sbjct: 569 LHVAAKYGKLEVANLLLQ---KSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPH 625
Query: 150 VPPTQASVMVDLSAKEGDED 169
+ ++AK+ D
Sbjct: 626 AAAKNGYTPLHIAAKKNQMD 645
Score = 39.7 bits (91), Expect = 0.002
Identities = 24/94 (25%), Positives = 39/94 (41%)
Query: 53 QGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWR 112
+G TA+HMAA +G ++ L Q Q + T LH +A + + LL G
Sbjct: 465 RGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGAS 524
Query: 113 AAEQNIMGKTALQLIYEKQYNEMETLLMSRDETL 146
G T L L + + ++ L+ +L
Sbjct: 525 PNAATTSGYTPLHLSAREGHEDVAAFLLDHGASL 558
Score = 38.9 bits (89), Expect = 0.004
Identities = 21/82 (25%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 28 NEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEG 87
++ G+ +++K L++ + +DA+ G T +H A +GH ++EML G
Sbjct: 276 SKRGNANMVKLLLDRG-AKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNG 334
Query: 88 NTALHFAALNNRVAAAEALLAH 109
+ LH A + + + LL H
Sbjct: 335 LSPLHMATQGDHLNCVQLLLQH 356
Score = 35.8 bits (81), Expect = 0.032
Identities = 27/99 (27%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
Query: 49 ARDEQGRTAVHMAAANGHMPILEMLFQFN-PQPNVPNDEGNTALHFAALNNRVAAAEALL 107
++ + G + +HMA H+ +++L Q N P +V ND TALH AA A+ LL
Sbjct: 329 SKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDY-LTALHVAAHCGHYKVAKVLL 387
Query: 108 AHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETL 146
+ + G T L + +K ++ LL+ ++
Sbjct: 388 DKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASI 426
Score = 35.8 bits (81), Expect = 0.032
Identities = 23/115 (20%), Positives = 49/115 (42%), Gaps = 1/115 (0%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
+ G +D++ L +N ++V+ ++ G T +H+AA + + E+L + G
Sbjct: 673 QEGHVDMVSLLLGRN-ANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGY 731
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRD 143
T LH + LL H + + G T L ++ + + +L+ +
Sbjct: 732 TPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNN 786
Score = 30.8 bits (68), Expect = 1.0
Identities = 35/143 (24%), Positives = 56/143 (39%), Gaps = 11/143 (7%)
Query: 8 DSEFREPLTDVDAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHM 67
D+ + L D F A + G ++ LE D + + A+H+AA
Sbjct: 161 DNGASQSLATEDGFTPLAVALQQGHDQVVSLLLEN-----DTKGKVRLPALHIAARKDDT 215
Query: 68 PILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGK---TAL 124
+L Q + +V + G T LH AA + A LL RAA + + T L
Sbjct: 216 KAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLN---RAAAVDFTARNDITPL 272
Query: 125 QLIYEKQYNEMETLLMSRDETLD 147
+ ++ M LL+ R +D
Sbjct: 273 HVASKRGNANMVKLLLDRGAKID 295
>gi|116875852 HECT domain and ankyrin repeat containing, E3
ubiquitin protein ligase 1 [Homo sapiens]
Length = 909
Score = 57.0 bits (136), Expect = 1e-08
Identities = 38/116 (32%), Positives = 53/116 (45%), Gaps = 2/116 (1%)
Query: 40 LEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNR 99
L ++ SDVD D G+TA+H+A NGH ++ L N PN G T L+FA + +
Sbjct: 150 LVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQ 209
Query: 100 VAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNE-METLLMSRDETLDTYVPPTQ 154
A+ LL G + G T L L + Y E E L+ T + TQ
Sbjct: 210 RDTAQILLLRGAKYLPDK-NGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQ 264
Score = 56.2 bits (134), Expect = 2e-08
Identities = 36/139 (25%), Positives = 65/139 (46%), Gaps = 3/139 (2%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G ++ L L+K ++ + +D G T +H+AA NG + L +++ N+ N+EG TA
Sbjct: 76 GSVECLVLLLKKG-ANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTA 134
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYV 150
+H+ A+N R L+ H ++ MG+TAL + + + L+ D D
Sbjct: 135 IHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLL--DSGADINR 192
Query: 151 PPTQASVMVDLSAKEGDED 169
P + + + G D
Sbjct: 193 PNVSGATPLYFACSHGQRD 211
Score = 50.1 bits (118), Expect = 2e-06
Identities = 34/122 (27%), Positives = 50/122 (40%), Gaps = 3/122 (2%)
Query: 45 SDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAE 104
+DV+ + +G TA+H A NG +L L Q +V + G TALH A N +
Sbjct: 122 ADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQ 181
Query: 105 ALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLSAK 164
LL G N+ G T L + +L+ R Y+P +DL +
Sbjct: 182 CLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA---KYLPDKNGVTPLDLCVQ 238
Query: 165 EG 166
G
Sbjct: 239 GG 240
Score = 35.8 bits (81), Expect = 0.032
Identities = 26/85 (30%), Positives = 38/85 (44%), Gaps = 3/85 (3%)
Query: 55 RTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAA 114
R+ +H+AA G + L +L + PN + G T LH AA N + LL + +A
Sbjct: 66 RSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEY---SA 122
Query: 115 EQNIMGKTALQLIYEKQYNEMETLL 139
+ NI L I+ N LL
Sbjct: 123 DVNICNNEGLTAIHWLAVNGRTELL 147
>gi|4506217 proteasome 26S non-ATPase subunit 10 isoform 1 [Homo
sapiens]
Length = 226
Score = 55.8 bits (133), Expect = 3e-08
Identities = 29/79 (36%), Positives = 44/79 (55%)
Query: 48 DARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALL 107
DA+D TA+H AAA G++ ++ +L + N+ + EGNT LH A RV A+ L+
Sbjct: 133 DAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLV 192
Query: 108 AHGWRAAEQNIMGKTALQL 126
+ G +N KT LQ+
Sbjct: 193 SQGASIYIENKEEKTPLQV 211
Score = 55.1 bits (131), Expect = 5e-08
Identities = 36/111 (32%), Positives = 52/111 (46%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
+G L+ LK + + S D+ RTA+H A + GH I+E L Q N +D G +
Sbjct: 16 SGKLEELKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWS 75
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLM 140
LH AA R +ALL G + N G T L K +E+ +L+
Sbjct: 76 PLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLL 126
Score = 47.0 bits (110), Expect = 1e-05
Identities = 41/153 (26%), Positives = 68/153 (44%), Gaps = 5/153 (3%)
Query: 47 VDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEAL 106
V+ +D+ G + +H+AA+ G I++ L Q N N G T LH+AA NR A L
Sbjct: 66 VNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Query: 107 LAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYVPPTQASVMVDLSAKEG 166
L G ++ TA+ K +M +L+ + T + T+ + + L+
Sbjct: 126 LEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKAS--TNIQDTEGNTPLHLAC--- 180
Query: 167 DEDEDNEREEKPTVEAKVAAERKTPPAPMAPAK 199
DE+ E + + A + E K P+ AK
Sbjct: 181 DEERVEEAKLLVSQGASIYIENKEEKTPLQVAK 213
Score = 44.3 bits (103), Expect = 9e-05
Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 1/117 (0%)
Query: 30 AGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNT 89
AG +++KA L K + V+A ++ G T +H AA+ I ML + P+ + T
Sbjct: 83 AGRDEIVKALLGKG-AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEAT 141
Query: 90 ALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETL 146
A+H AA + LL + Q+ G T L L +++ E LL+S+ ++
Sbjct: 142 AMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASI 198
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 55.8 bits (133), Expect = 3e-08
Identities = 39/129 (30%), Positives = 58/129 (44%), Gaps = 8/129 (6%)
Query: 1 MEPYYEPDSEFREPLTDV-----DAFLDSARYNEAGDLDLLKAYLEKNPSDVDARDEQGR 55
M+P Y P +E T+ D L + E GD + + + L K + D +G+
Sbjct: 1 MQPTYLPWLSAKEKKTNEWNKNDDRLLQAV---ENGDAEKVASLLGKKGASATKHDSEGK 57
Query: 56 TAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAE 115
TA H+AAA GH+ L ++ + G++ALH AA N+ LL A
Sbjct: 58 TAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAES 117
Query: 116 QNIMGKTAL 124
+ GKTAL
Sbjct: 118 VDSSGKTAL 126
Score = 53.9 bits (128), Expect = 1e-07
Identities = 51/199 (25%), Positives = 85/199 (42%), Gaps = 29/199 (14%)
Query: 51 DEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHG 110
D G+TA+H AAA G + +++L + N+ + +GN L A N LL HG
Sbjct: 119 DSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHG 178
Query: 111 WRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDT----------YVPPTQASVMVD 160
+N G+TAL L E + L+ + L+ Y ++ + +
Sbjct: 179 ADVNSRNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALHYSKLSENAGIQS 238
Query: 161 LSAKEGDEDEDNEREEKPTVE---AKVAAE-------RKTPPAPMAPAKKIVPSASEAPA 210
L + +D D + KP +K+++E RK PP P++P + S+ +
Sbjct: 239 LLLSKISQDADLKTPTKPKQHDQVSKISSERSGTPKKRKAPPPPISPTQ-----LSDVSS 293
Query: 211 PVVPVDATTSTQMLGSASV 229
P + TST + G SV
Sbjct: 294 P----RSITSTPLSGKESV 308
Score = 35.8 bits (81), Expect = 0.032
Identities = 26/103 (25%), Positives = 44/103 (42%), Gaps = 4/103 (3%)
Query: 41 EKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRV 100
EK ++ + D++ AV A + +L + + EG TA H AA V
Sbjct: 13 EKKTNEWNKNDDRLLQAVENGDAE---KVASLLGKKGASATKHDSEGKTAFHLAAAKGHV 69
Query: 101 AAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNE-METLLMSR 142
++ HG Q+ G +AL L + ++E + LL S+
Sbjct: 70 ECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 112
>gi|38327522 cardiac ankyrin repeat protein [Homo sapiens]
Length = 319
Score = 55.8 bits (133), Expect = 3e-08
Identities = 35/104 (33%), Positives = 50/104 (48%), Gaps = 1/104 (0%)
Query: 28 NEAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEG 87
+ G+LD+LK L K + + ARD+ TA+H+A GH E L N + EG
Sbjct: 194 SRGGNLDVLKLLLNKG-AKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREG 252
Query: 88 NTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQ 131
+T LH A NR L+ +G +N GKT + L+ Q
Sbjct: 253 DTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHWQ 296
Score = 51.6 bits (122), Expect = 6e-07
Identities = 41/143 (28%), Positives = 71/143 (49%), Gaps = 6/143 (4%)
Query: 6 EPDSEFREPLTDVDAFLDSARYNEAGDLDLLKAYL-EKNPSDVDARDEQGRTAVHMAAAN 64
EP+ E DV FL +A N+ L +++ +L +KN DV DE RTA+H A
Sbjct: 109 EPEPEIITEPVDVPTFLKAALENK---LPVVEKFLSDKNNPDVC--DEYKRTALHRACLE 163
Query: 65 GHMPILEMLFQFNPQPNVPNDEGNTALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
GH+ I+E L + Q + +TA+H+A+ + + LL G + + ++ + TAL
Sbjct: 164 GHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTAL 223
Query: 125 QLIYEKQYNEMETLLMSRDETLD 147
+ + E L++ + L+
Sbjct: 224 HVAVRTGHYECAEHLIACEADLN 246
>gi|156104901 ankyrin repeat domain 20 family, member A1 [Homo
sapiens]
Length = 823
Score = 55.8 bits (133), Expect = 3e-08
Identities = 37/110 (33%), Positives = 56/110 (50%), Gaps = 1/110 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD ++ L + D+DA D+Q RTA+H+A +GH+ ++ +L Q +V + E T
Sbjct: 44 GDAAEVERCLARRSGDLDALDKQHRTALHLACTSGHVQVVTLLVNRKCQIDVCDKENRTP 103
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQ-LIYEKQYNEMETLL 139
L A A A LL HG ++I G TAL +Y + + E LL
Sbjct: 104 LIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLL 153
>gi|149363679 ankyrin repeat domain 20 family, member A4 [Homo
sapiens]
Length = 823
Score = 55.8 bits (133), Expect = 3e-08
Identities = 37/110 (33%), Positives = 57/110 (51%), Gaps = 1/110 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
GD ++ L + ++DA D+Q RTA+H+A A+GH+ ++ +L Q +V + E T
Sbjct: 44 GDAAEVERCLARRSGELDALDKQHRTALHLACASGHVQVVTLLVNRKCQIDVCDKENRTP 103
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQ-LIYEKQYNEMETLL 139
L A A A LL HG ++I G TAL +Y + + E LL
Sbjct: 104 LIQAVHCQEEACAVILLEHGANPNLKDIYGNTALHYAVYSESTSLAEKLL 153
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 55.5 bits (132), Expect = 4e-08
Identities = 37/129 (28%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G+L+ L A L D+ D GR A+H+AA GH L+ L Q+N + +G TA
Sbjct: 66 GNLECLNAILIHGV-DITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTA 124
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYV 150
LH AA+ + ++ + L HG +++ G+T L L + + LL+ R +++
Sbjct: 125 LHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRD 184
Query: 151 PPTQASVMV 159
+ ++M+
Sbjct: 185 KQNRTALML 193
Score = 41.6 bits (96), Expect = 6e-04
Identities = 23/96 (23%), Positives = 41/96 (42%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
E GD++ + + L K + D +GR+ H+ + G++ L + + G
Sbjct: 30 ERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGR 89
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
ALH AA + LL + ++ G+TAL
Sbjct: 90 NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTAL 125
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 55.5 bits (132), Expect = 4e-08
Identities = 37/129 (28%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Query: 31 GDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGNTA 90
G+L+ L A L D+ D GR A+H+AA GH L+ L Q+N + +G TA
Sbjct: 79 GNLECLNAILIHGV-DITTSDTAGRNALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTA 137
Query: 91 LHFAALNNRVAAAEALLAHGWRAAEQNIMGKTALQLIYEKQYNEMETLLMSRDETLDTYV 150
LH AA+ + ++ + L HG +++ G+T L L + + LL+ R +++
Sbjct: 138 LHDAAMADCPSSIQLLCDHGASVNAKDVDGRTPLVLATQMSRPTICQLLIDRGADVNSRD 197
Query: 151 PPTQASVMV 159
+ ++M+
Sbjct: 198 KQNRTALML 206
Score = 41.6 bits (96), Expect = 6e-04
Identities = 23/96 (23%), Positives = 41/96 (42%)
Query: 29 EAGDLDLLKAYLEKNPSDVDARDEQGRTAVHMAAANGHMPILEMLFQFNPQPNVPNDEGN 88
E GD++ + + L K + D +GR+ H+ + G++ L + + G
Sbjct: 43 ERGDVEKVTSILAKKGVNPGKLDVEGRSVFHVVTSKGNLECLNAILIHGVDITTSDTAGR 102
Query: 89 TALHFAALNNRVAAAEALLAHGWRAAEQNIMGKTAL 124
ALH AA + LL + ++ G+TAL
Sbjct: 103 NALHLAAKYGHALCLQKLLQYNCPTEHADLQGRTAL 138
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.351
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,997,858
Number of Sequences: 37866
Number of extensions: 413174
Number of successful extensions: 5442
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 357
Number of HSP's successfully gapped in prelim test: 180
Number of HSP's that attempted gapping in prelim test: 3301
Number of HSP's gapped (non-prelim): 1953
length of query: 233
length of database: 18,247,518
effective HSP length: 99
effective length of query: 134
effective length of database: 14,498,784
effective search space: 1942837056
effective search space used: 1942837056
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.