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Search of human proteins with 89026256
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89026256 PREDICTED: similar to actin related protein 2/3
complex subunit 1B [Homo sapiens]
(370 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|89026256 PREDICTED: similar to actin related protein 2/3 comp... 767 0.0
gi|5031601 actin related protein 2/3 complex subunit 1B [Homo sa... 735 0.0
gi|22907052 actin related protein 2/3 complex subunit 1A [Homo s... 520 e-148
gi|4757988 WD repeat domain 39 [Homo sapiens] 63 4e-10
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 57 3e-08
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 53 4e-07
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 53 4e-07
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 53 4e-07
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 53 4e-07
gi|210032390 SEC13 protein isoform 2 [Homo sapiens] 52 7e-07
gi|34335134 SEC13 protein isoform 1 [Homo sapiens] 52 7e-07
gi|21071067 TBP-associated factor 5 [Homo sapiens] 51 1e-06
gi|19913367 transducin beta-like 1Y [Homo sapiens] 51 2e-06
gi|19913365 transducin beta-like 1Y [Homo sapiens] 51 2e-06
gi|15150805 transducin beta-like 1Y [Homo sapiens] 51 2e-06
gi|26665869 WD repeat domain 51B [Homo sapiens] 44 2e-04
gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens] 43 4e-04
gi|46409657 WD repeat domain 56 [Homo sapiens] 43 4e-04
gi|34996489 pleckstrin homology domain interacting protein [Homo... 43 5e-04
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 42 7e-04
gi|118402582 cell division cycle 20 [Homo sapiens] 42 9e-04
gi|55769546 PAK1 interacting protein 1 [Homo sapiens] 42 9e-04
gi|22749037 WD repeat domain 65 [Homo sapiens] 41 0.002
gi|58331266 WD repeat domain 59 [Homo sapiens] 41 0.002
gi|32189425 WD repeat domain 69 [Homo sapiens] 41 0.002
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 39 0.006
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 39 0.006
gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 39 0.007
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 39 0.007
gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens] 39 0.010
>gi|89026256 PREDICTED: similar to actin related protein 2/3 complex
subunit 1B [Homo sapiens]
Length = 370
Score = 767 bits (1981), Expect = 0.0
Identities = 370/370 (100%), Positives = 370/370 (100%)
Query: 1 MYAFSSWMSRRRGRVKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAP 60
MYAFSSWMSRRRGRVKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAP
Sbjct: 1 MYAFSSWMSRRRGRVKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAP 60
Query: 61 ESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISI 120
ESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISI
Sbjct: 61 ESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISI 120
Query: 121 CYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAP 180
CYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAP
Sbjct: 121 CYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAP 180
Query: 181 TPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLAS 240
TPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLAS
Sbjct: 181 TPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLAS 240
Query: 241 ETLPLVALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARERF 300
ETLPLVALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARERF
Sbjct: 241 ETLPLVALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARERF 300
Query: 301 QNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSL 360
QNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSL
Sbjct: 301 QNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSL 360
Query: 361 ESALKDLKIK 370
ESALKDLKIK
Sbjct: 361 ESALKDLKIK 370
>gi|5031601 actin related protein 2/3 complex subunit 1B [Homo
sapiens]
Length = 372
Score = 735 bits (1898), Expect = 0.0
Identities = 354/355 (99%), Positives = 355/355 (100%)
Query: 16 KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY
Sbjct: 18 KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 77
Query: 76 VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHI 135
VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHI
Sbjct: 78 VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHI 137
Query: 136 KKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFE 195
KKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFE
Sbjct: 138 KKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFE 197
Query: 196 SSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITDNS 255
SSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPL+ALTFITDNS
Sbjct: 198 SSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLLALTFITDNS 257
Query: 256 LVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARERFQNLDKKASSEGGTAA 315
LVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARERFQNLDKKASSEGGTAA
Sbjct: 258 LVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARERFQNLDKKASSEGGTAA 317
Query: 316 GAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIK 370
GAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIK
Sbjct: 318 GAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKIK 372
>gi|22907052 actin related protein 2/3 complex subunit 1A [Homo
sapiens]
Length = 370
Score = 520 bits (1339), Expect = e-148
Identities = 241/356 (67%), Positives = 300/356 (84%), Gaps = 6/356 (1%)
Query: 16 KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
+DRTQIA+ PNNHEVHIY+K+G++W K HELKEHNG +TGIDWAP+S+RIVTCG DRNAY
Sbjct: 18 RDRTQIALSPNNHEVHIYKKNGSQWVKAHELKEHNGHITGIDWAPKSDRIVTCGADRNAY 77
Query: 76 VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHI 135
VW+ K WKPTLVILRINRAA V+W+P ENKFAVGSG+R+IS+CYFE ENDWWV KHI
Sbjct: 78 VWSQKDGVWKPTLVILRINRAATFVKWSPLENKFAVGSGARLISVCYFESENDWWVSKHI 137
Query: 136 KKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELM-- 193
KKPIRSTVLSLDWHPNNVLLAAGSCDFKCR+FSAYIKEV+E+PA TPWGSKMPFG+LM
Sbjct: 138 KKPIRSTVLSLDWHPNNVLLAAGSCDFKCRVFSAYIKEVDEKPASTPWGSKMPFGQLMSE 197
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
F S + GWVHGV FSASGSR+AWVSHDSTV +ADA K + V+TL +E LPL++++F+++
Sbjct: 198 FGGSGTGGWVHGVSFSASGSRLAWVSHDSTVSVADASKSVQVSTLKTEFLPLLSVSFVSE 257
Query: 254 NSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARERFQNLDKKASSEGGT 313
NS+VAAGHDC P+LF YD G L+F +LD+PKQS QR ++A ERF+N+DK+A++E
Sbjct: 258 NSVVAAGHDCCPMLFNYD-DRGCLTFVSKLDIPKQSIQRNMSAMERFRNMDKRATTEDRN 316
Query: 314 AAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVKSLESALKDLKI 369
A L++LH+NS++Q+S+ K C +FCTTG+DG M+IWD K+LES+++ L+I
Sbjct: 317 TA---LETLHQNSITQVSIYEVDKQDCRKFCTTGIDGAMTIWDFKTLESSIQGLRI 369
>gi|4757988 WD repeat domain 39 [Homo sapiens]
Length = 339
Score = 63.2 bits (152), Expect = 4e-10
Identities = 40/146 (27%), Positives = 70/146 (47%), Gaps = 3/146 (2%)
Query: 32 IYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVIL 91
I++K+ + V L+ H +V + WAP N + TC D++ +VW + + +L
Sbjct: 87 IWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECVSVL 146
Query: 92 RIN-RAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHP 150
+ + + V W P++ A S + + + +E D WVC + STV SL + P
Sbjct: 147 NSHTQDVKHVVWHPSQELLASASYDDTVKL--YREEEDDWVCCATLEGHESTVWSLAFDP 204
Query: 151 NNVLLAAGSCDFKCRIFSAYIKEVEE 176
+ LA+ S D RI+ Y+ E+
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQ 230
Score = 57.0 bits (136), Expect = 3e-08
Identities = 48/207 (23%), Positives = 77/207 (37%), Gaps = 18/207 (8%)
Query: 19 TQIAICPNNHEVHIYEKSGAKWTKVHELKE-HNGQVTGIDWAPESNRIVTCGTDRNAYVW 77
T +A C + + I+ G W L E H V + W+P N + + D +W
Sbjct: 29 TLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDATTCIW 88
Query: 78 TLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKK 137
++ + + V WAP+ N A S + + + ++E D + C +
Sbjct: 89 KKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEE-DEYECVSVLN 147
Query: 138 PIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESS 197
V + WHP+ LLA+ S D +++ R W E
Sbjct: 148 SHTQDVKHVVWHPSQELLASASYDDTVKLY---------REEEDDWVCC-----ATLEGH 193
Query: 198 SSCGWVHGVCFSASGSRVAWVSHDSTV 224
S W + F SG R+A S D TV
Sbjct: 194 ESTVW--SLAFDPSGQRLASCSDDRTV 218
Score = 50.1 bits (118), Expect = 3e-06
Identities = 54/208 (25%), Positives = 84/208 (40%), Gaps = 20/208 (9%)
Query: 58 WAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILR-INRAARCVRWAPNENKFAVGSGSR 116
W P + +CG DR +W +G +W V+ R R V W+P N A S S
Sbjct: 24 WNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLA--SASF 81
Query: 117 VISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEE 176
+ C +++ D + C + + V S+ W P+ LLA S D S ++ EV+E
Sbjct: 82 DATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRD-----KSVWVWEVDE 136
Query: 177 RPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCL--ADADKKMA 234
E + +S V V + S +A S+D TV L + D +
Sbjct: 137 EDE----------YECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVC 186
Query: 235 VATLASETLPLVALTFITDNSLVAAGHD 262
ATL + +L F +A+ D
Sbjct: 187 CATLEGHESTVWSLAFDPSGQRLASCSD 214
Score = 31.6 bits (70), Expect = 1.2
Identities = 29/151 (19%), Positives = 50/151 (33%), Gaps = 19/151 (12%)
Query: 30 VHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWT--LKGR----- 82
V +Y + W L+ H V + + P R+ +C DR +W L G
Sbjct: 174 VKLYREEEDDWVCCATLEGHESTVWSLAFDPSGQRLASCSDDRTVRIWRQYLPGNEQGVA 233
Query: 83 ------TWKPTLVILRI-NRAARCVRWAPNENKFAVGSGSRVISICYFEQEND-----WW 130
+WK + +R + W A G I + + +D +
Sbjct: 234 CSGSDPSWKCICTLSGFHSRTIYDIAWCQLTGALATACGDDAIRVFQEDPNSDPQQPTFS 293
Query: 131 VCKHIKKPIRSTVLSLDWHPNNVLLAAGSCD 161
+ H+ + V + W+P L A D
Sbjct: 294 LTAHLHQAHSQDVNCVAWNPKEPGLLASCSD 324
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 57.0 bits (136), Expect = 3e-08
Identities = 62/250 (24%), Positives = 97/250 (38%), Gaps = 56/250 (22%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WTK L +H G + + W + N I++ G D+ +W T +
Sbjct: 245 YDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWD--AHTGEAKQ 302
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRS------T 142
+ A V W N N FA S I +C Q+ +PI++
Sbjct: 303 QFPFHSAPALDVDWQSN-NTFASCSTDMCIHVCKLGQD----------RPIKTFQGHTNE 351
Query: 143 VLSLDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFG 190
V ++ W P LLA+ S D +I+S A+ KE+ + +PT G+ P
Sbjct: 352 VNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNA 411
Query: 191 ELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTF 250
LM S+S DSTV L D D+ + + TL P+ ++ F
Sbjct: 412 NLMLASAS---------------------FDSTVRLWDVDRGICIHTLTKHQEPVYSVAF 450
Query: 251 ITDNSLVAAG 260
D +A+G
Sbjct: 451 SPDGRYLASG 460
Score = 51.2 bits (121), Expect = 1e-06
Identities = 41/188 (21%), Positives = 75/188 (39%), Gaps = 26/188 (13%)
Query: 49 HNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENK 108
H +V I W P N + +C D +W++K L N+ ++W+P
Sbjct: 348 HTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDL--QAHNKEIYTIKWSPTGPG 405
Query: 109 FAVGSGSRVISICYFEQENDWW-----VCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFK 163
+ + +++ F+ W +C H + V S+ + P+ LA+GS D
Sbjct: 406 TNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKC 465
Query: 164 CRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDST 223
I++ T G+ + S G + VC++A+G +V + D +
Sbjct: 466 VHIWN------------TQTGA-------LVHSYRGTGGIFEVCWNAAGDKVGASASDGS 506
Query: 224 VCLADADK 231
VC+ D K
Sbjct: 507 VCVLDLRK 514
Score = 33.1 bits (74), Expect = 0.41
Identities = 32/118 (27%), Positives = 45/118 (38%), Gaps = 15/118 (12%)
Query: 52 QVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVR-WAPNENKFA 110
+V G P + +V G + ++ W P +L R W +EN +
Sbjct: 150 EVDGDVEIPPNKAVVLRGHESEVFICA-----WNPVSDLLASGSGDSTARIWNLSENSTS 204
Query: 111 VGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFS 168
GS V+ C E D P V SLDW+ LLA GS D RI++
Sbjct: 205 -GSTQLVLRHCIREGGQD--------VPSNKDVTSLDWNSEGTLLATGSYDGFARIWT 253
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 53.1 bits (126), Expect = 4e-07
Identities = 49/221 (22%), Positives = 89/221 (40%), Gaps = 28/221 (12%)
Query: 16 KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
++ T A C + +H+ + K + H +V I W P + +C D
Sbjct: 329 QNNTTFASCSTDMCIHVCRLGCDRPVKTFQ--GHTNEVNAIKWDPSGMLLASCSDDMTLK 386
Query: 76 VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWW----- 130
+W++K L N+ ++W+P + + + +++ F+ W
Sbjct: 387 IWSMKQEVCIHDL--QAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERG 444
Query: 131 VCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFG 190
VC H + V S+ + P+ LA+GS D KC +I W ++ G
Sbjct: 445 VCTHTLTKHQEPVYSVAFSPDGKYLASGSFD-KC----VHI-----------WNTQS--G 486
Query: 191 ELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADK 231
L+ S G + VC++A G +V + D +VC+ D K
Sbjct: 487 NLV-HSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 46.6 bits (109), Expect = 4e-05
Identities = 56/247 (22%), Positives = 93/247 (37%), Gaps = 50/247 (20%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WT+ L +H G + + W + N I++ G D+ +W T +
Sbjct: 257 YDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIW--DAHTGEAKQ 314
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR---STVLS 145
+ A V W N FA S I +C C K + + V +
Sbjct: 315 QFPFHSAPALDVDW-QNNTTFASCSTDMCIHVCRLG-------CDRPVKTFQGHTNEVNA 366
Query: 146 LDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFGELM 193
+ W P+ +LLA+ S D +I+S A+ KE+ + +PT + P +M
Sbjct: 367 IKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIM 426
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
S+ S DSTV L D ++ + TL P+ ++ F D
Sbjct: 427 LASA---------------------SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 465
Query: 254 NSLVAAG 260
+A+G
Sbjct: 466 GKYLASG 472
Score = 37.7 bits (86), Expect = 0.017
Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 34/128 (26%)
Query: 41 TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCV 100
+K L+ H +V W P S+ + + D A +W L
Sbjct: 172 SKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL--------------------- 210
Query: 101 RWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSC 160
NEN GS V+ C E +D P V SLDW+ N LLA GS
Sbjct: 211 ----NENSNG-GSTQLVLRHCIREGGHD--------VPSNKDVTSLDWNTNGTLLATGSY 257
Query: 161 DFKCRIFS 168
D RI++
Sbjct: 258 DGFARIWT 265
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 53.1 bits (126), Expect = 4e-07
Identities = 49/221 (22%), Positives = 89/221 (40%), Gaps = 28/221 (12%)
Query: 16 KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
++ T A C + +H+ + K + H +V I W P + +C D
Sbjct: 329 QNNTTFASCSTDMCIHVCRLGCDRPVKTFQ--GHTNEVNAIKWDPSGMLLASCSDDMTLK 386
Query: 76 VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWW----- 130
+W++K L N+ ++W+P + + + +++ F+ W
Sbjct: 387 IWSMKQEVCIHDL--QAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERG 444
Query: 131 VCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFG 190
VC H + V S+ + P+ LA+GS D KC +I W ++ G
Sbjct: 445 VCTHTLTKHQEPVYSVAFSPDGKYLASGSFD-KC----VHI-----------WNTQS--G 486
Query: 191 ELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADK 231
L+ S G + VC++A G +V + D +VC+ D K
Sbjct: 487 NLV-HSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 526
Score = 46.6 bits (109), Expect = 4e-05
Identities = 56/247 (22%), Positives = 93/247 (37%), Gaps = 50/247 (20%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WT+ L +H G + + W + N I++ G D+ +W T +
Sbjct: 257 YDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIW--DAHTGEAKQ 314
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR---STVLS 145
+ A V W N FA S I +C C K + + V +
Sbjct: 315 QFPFHSAPALDVDW-QNNTTFASCSTDMCIHVCRLG-------CDRPVKTFQGHTNEVNA 366
Query: 146 LDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFGELM 193
+ W P+ +LLA+ S D +I+S A+ KE+ + +PT + P +M
Sbjct: 367 IKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIM 426
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
S+ S DSTV L D ++ + TL P+ ++ F D
Sbjct: 427 LASA---------------------SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 465
Query: 254 NSLVAAG 260
+A+G
Sbjct: 466 GKYLASG 472
Score = 37.7 bits (86), Expect = 0.017
Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 34/128 (26%)
Query: 41 TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCV 100
+K L+ H +V W P S+ + + D A +W L
Sbjct: 172 SKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL--------------------- 210
Query: 101 RWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSC 160
NEN GS V+ C E +D P V SLDW+ N LLA GS
Sbjct: 211 ----NENSNG-GSTQLVLRHCIREGGHD--------VPSNKDVTSLDWNTNGTLLATGSY 257
Query: 161 DFKCRIFS 168
D RI++
Sbjct: 258 DGFARIWT 265
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 53.1 bits (126), Expect = 4e-07
Identities = 49/221 (22%), Positives = 89/221 (40%), Gaps = 28/221 (12%)
Query: 16 KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
++ T A C + +H+ + K + H +V I W P + +C D
Sbjct: 380 QNNTTFASCSTDMCIHVCRLGCDRPVKTFQ--GHTNEVNAIKWDPSGMLLASCSDDMTLK 437
Query: 76 VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWW----- 130
+W++K L N+ ++W+P + + + +++ F+ W
Sbjct: 438 IWSMKQEVCIHDL--QAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERG 495
Query: 131 VCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFG 190
VC H + V S+ + P+ LA+GS D KC +I W ++ G
Sbjct: 496 VCTHTLTKHQEPVYSVAFSPDGKYLASGSFD-KC----VHI-----------WNTQS--G 537
Query: 191 ELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADK 231
L+ S G + VC++A G +V + D +VC+ D K
Sbjct: 538 NLV-HSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 46.6 bits (109), Expect = 4e-05
Identities = 56/247 (22%), Positives = 93/247 (37%), Gaps = 50/247 (20%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WT+ L +H G + + W + N I++ G D+ +W T +
Sbjct: 308 YDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIW--DAHTGEAKQ 365
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR---STVLS 145
+ A V W N FA S I +C C K + + V +
Sbjct: 366 QFPFHSAPALDVDW-QNNTTFASCSTDMCIHVCRLG-------CDRPVKTFQGHTNEVNA 417
Query: 146 LDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFGELM 193
+ W P+ +LLA+ S D +I+S A+ KE+ + +PT + P +M
Sbjct: 418 IKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIM 477
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
S+ S DSTV L D ++ + TL P+ ++ F D
Sbjct: 478 LASA---------------------SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 516
Query: 254 NSLVAAG 260
+A+G
Sbjct: 517 GKYLASG 523
Score = 37.7 bits (86), Expect = 0.017
Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 34/128 (26%)
Query: 41 TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCV 100
+K L+ H +V W P S+ + + D A +W L
Sbjct: 223 SKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL--------------------- 261
Query: 101 RWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSC 160
NEN GS V+ C E +D P V SLDW+ N LLA GS
Sbjct: 262 ----NENSNG-GSTQLVLRHCIREGGHD--------VPSNKDVTSLDWNTNGTLLATGSY 308
Query: 161 DFKCRIFS 168
D RI++
Sbjct: 309 DGFARIWT 316
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 53.1 bits (126), Expect = 4e-07
Identities = 49/221 (22%), Positives = 89/221 (40%), Gaps = 28/221 (12%)
Query: 16 KDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
++ T A C + +H+ + K + H +V I W P + +C D
Sbjct: 380 QNNTTFASCSTDMCIHVCRLGCDRPVKTFQ--GHTNEVNAIKWDPSGMLLASCSDDMTLK 437
Query: 76 VWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWW----- 130
+W++K L N+ ++W+P + + + +++ F+ W
Sbjct: 438 IWSMKQEVCIHDL--QAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDIERG 495
Query: 131 VCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFG 190
VC H + V S+ + P+ LA+GS D KC +I W ++ G
Sbjct: 496 VCTHTLTKHQEPVYSVAFSPDGKYLASGSFD-KC----VHI-----------WNTQS--G 537
Query: 191 ELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADK 231
L+ S G + VC++A G +V + D +VC+ D K
Sbjct: 538 NLV-HSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 577
Score = 46.6 bits (109), Expect = 4e-05
Identities = 56/247 (22%), Positives = 93/247 (37%), Gaps = 50/247 (20%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WT+ L +H G + + W + N I++ G D+ +W T +
Sbjct: 308 YDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTIIW--DAHTGEAKQ 365
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR---STVLS 145
+ A V W N FA S I +C C K + + V +
Sbjct: 366 QFPFHSAPALDVDW-QNNTTFASCSTDMCIHVCRLG-------CDRPVKTFQGHTNEVNA 417
Query: 146 LDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFGELM 193
+ W P+ +LLA+ S D +I+S A+ KE+ + +PT + P +M
Sbjct: 418 IKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIM 477
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
S+ S DSTV L D ++ + TL P+ ++ F D
Sbjct: 478 LASA---------------------SFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPD 516
Query: 254 NSLVAAG 260
+A+G
Sbjct: 517 GKYLASG 523
Score = 37.7 bits (86), Expect = 0.017
Identities = 35/128 (27%), Positives = 47/128 (36%), Gaps = 34/128 (26%)
Query: 41 TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCV 100
+K L+ H +V W P S+ + + D A +W L
Sbjct: 223 SKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNL--------------------- 261
Query: 101 RWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSC 160
NEN GS V+ C E +D P V SLDW+ N LLA GS
Sbjct: 262 ----NENSNG-GSTQLVLRHCIREGGHD--------VPSNKDVTSLDWNTNGTLLATGSY 308
Query: 161 DFKCRIFS 168
D RI++
Sbjct: 309 DGFARIWT 316
>gi|210032390 SEC13 protein isoform 2 [Homo sapiens]
Length = 308
Score = 52.4 bits (124), Expect = 7e-07
Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Query: 19 TQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPE--SNRIVTCGTDRNAYV 76
T++A C ++ V I++ + +L+ H G V + WA N + +C DR +
Sbjct: 12 TRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVII 71
Query: 77 WTLKGRTWKPTLVILRINRAARCVRWAPNENK--FAVGSGSRVISICYFEQENDWWVCK 133
W + TW+ + + + V WAP++ A GS IS+ + E W V K
Sbjct: 72 WREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKK 130
Score = 50.1 bits (118), Expect = 3e-06
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 34 EKSGAKWTKVHELKEHNGQVTGIDWAPE----SNRIVTCGTDRNAYVWT---LKGRTWKP 86
E+ +W + +L+ H+ V + WAP ++ I +C D ++WT TW P
Sbjct: 182 EEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSP 241
Query: 87 TLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVC 132
L + + N V W+ N AV G +++ + E + WVC
Sbjct: 242 KL-LHKFNDVVWHVSWSITANILAVSGGDNKVTL-WKESVDGQWVC 285
Score = 40.4 bits (93), Expect = 0.003
Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 24/131 (18%)
Query: 21 IAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAP-ESNRIVTCGTDRNAYVWTL 79
+A C + +V I+ + W K HE H+ V + WAP + I+ CG+ A +L
Sbjct: 60 LASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAI--SL 117
Query: 80 KGRTWKPTLVILRINRA----ARCVRWAPNE-----------------NKFAVGSGSRVI 118
T + + +IN A V WAP +FA G +I
Sbjct: 118 LTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLI 177
Query: 119 SICYFEQENDW 129
+ E++ W
Sbjct: 178 KLWKEEEDGQW 188
>gi|34335134 SEC13 protein isoform 1 [Homo sapiens]
Length = 322
Score = 52.4 bits (124), Expect = 7e-07
Identities = 31/119 (26%), Positives = 53/119 (44%), Gaps = 4/119 (3%)
Query: 19 TQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPE--SNRIVTCGTDRNAYV 76
T++A C ++ V I++ + +L+ H G V + WA N + +C DR +
Sbjct: 26 TRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVII 85
Query: 77 WTLKGRTWKPTLVILRINRAARCVRWAPNENK--FAVGSGSRVISICYFEQENDWWVCK 133
W + TW+ + + + V WAP++ A GS IS+ + E W V K
Sbjct: 86 WREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKK 144
Score = 50.1 bits (118), Expect = 3e-06
Identities = 28/106 (26%), Positives = 48/106 (45%), Gaps = 9/106 (8%)
Query: 34 EKSGAKWTKVHELKEHNGQVTGIDWAPE----SNRIVTCGTDRNAYVWT---LKGRTWKP 86
E+ +W + +L+ H+ V + WAP ++ I +C D ++WT TW P
Sbjct: 196 EEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSP 255
Query: 87 TLVILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVC 132
L + + N V W+ N AV G +++ + E + WVC
Sbjct: 256 KL-LHKFNDVVWHVSWSITANILAVSGGDNKVTL-WKESVDGQWVC 299
Score = 40.4 bits (93), Expect = 0.003
Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 24/131 (18%)
Query: 21 IAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAP-ESNRIVTCGTDRNAYVWTL 79
+A C + +V I+ + W K HE H+ V + WAP + I+ CG+ A +L
Sbjct: 74 LASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAI--SL 131
Query: 80 KGRTWKPTLVILRINRA----ARCVRWAPNE-----------------NKFAVGSGSRVI 118
T + + +IN A V WAP +FA G +I
Sbjct: 132 LTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLI 191
Query: 119 SICYFEQENDW 129
+ E++ W
Sbjct: 192 KLWKEEEDGQW 202
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 51.2 bits (121), Expect = 1e-06
Identities = 58/238 (24%), Positives = 90/238 (37%), Gaps = 48/238 (20%)
Query: 47 KEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNE 106
K HN V ++P V+ G DR A +W ++P + C R+ PN
Sbjct: 582 KGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDH--YQPLRIFAGHLADVNCTRFHPNS 639
Query: 107 NKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRI 166
N A GS R + + N C I + + SL + PN LA G+ D + +
Sbjct: 640 NYVATGSADRTVRLWDVLNGN----CVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLL 695
Query: 167 FSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCL 226
+ G + GEL + + C + FS G +A S D+TV L
Sbjct: 696 WDI--------------GHGLMVGELKGHTDTVCS----LRFSRDGEILASGSMDNTVRL 737
Query: 227 ADADK------------------------KMAVATLASETLPLVALTFITDNSLVAAG 260
DA K ++ + T +++ P+V L F N ++AAG
Sbjct: 738 WDAIKAFEDLETDDFTTATGHINLPENSQELLLGTYMTKSTPVVHLHFTRRNLVLAAG 795
Score = 44.3 bits (103), Expect = 2e-04
Identities = 48/218 (22%), Positives = 85/218 (38%), Gaps = 36/218 (16%)
Query: 49 HNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENK 108
H+G V G ++P+ N +++ D +W+L +T+ + N +++P
Sbjct: 542 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSL--QTFTCLVGYKGHNYPVWDTQFSPYGYY 599
Query: 109 FAVGSGSRVISICYFEQENDWWVCKHIKKPIR------STVLSLDWHPNNVLLAAGSCDF 162
F G RV + W H +P+R + V +HPN+ +A GS D
Sbjct: 600 FVSGGHDRVARL---------WATDHY-QPLRIFAGHLADVNCTRFHPNSNYVATGSADR 649
Query: 163 KCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDS 222
R++ G + + G +H + FS +G +A + D
Sbjct: 650 TVRLWDVL------------------NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDG 691
Query: 223 TVCLADADKKMAVATLASETLPLVALTFITDNSLVAAG 260
V L D + V L T + +L F D ++A+G
Sbjct: 692 RVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASG 729
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/191 (21%), Positives = 75/191 (39%), Gaps = 26/191 (13%)
Query: 43 VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRW 102
V + H +V I W P + +C D +W++K L ++ ++W
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDL--QAHSKEIYTIKW 409
Query: 103 APNENKFAVGSGSRVISICYFEQENDWW-----VCKHIKKPIRSTVLSLDWHPNNVLLAA 157
+P + + S +++ F+ W VC H + V S+ + P+ LA+
Sbjct: 410 SPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 158 GSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAW 217
GS D I++ T GS + S G + VC++A G +V
Sbjct: 470 GSFDKYVHIWN------------TQSGS-------LVHSYQGTGGIFEVCWNARGDKVGA 510
Query: 218 VSHDSTVCLAD 228
+ D +VC+ D
Sbjct: 511 SASDGSVCVLD 521
Score = 48.9 bits (115), Expect = 7e-06
Identities = 56/247 (22%), Positives = 94/247 (38%), Gaps = 50/247 (20%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WT+ L +H G + + W + N +++ G D+ +W T +
Sbjct: 255 YDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIW--DAHTGEAKQ 312
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR---STVLS 145
+ A V W N FA S I +C C H K + + V +
Sbjct: 313 QFPFHSAPALDVDW-QNNMTFASCSTDMCIHVCRLG-------CDHPVKTFQGHTNEVNA 364
Query: 146 LDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFGELM 193
+ W P+ +LLA+ S D +I+S A+ KE+ + +PT + P +M
Sbjct: 365 IKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIM 424
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
S+ S DSTV L D ++ + TL P+ ++ F D
Sbjct: 425 LASA---------------------SFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPD 463
Query: 254 NSLVAAG 260
+A+G
Sbjct: 464 GKYLASG 470
Score = 38.5 bits (88), Expect = 0.010
Identities = 41/148 (27%), Positives = 59/148 (39%), Gaps = 23/148 (15%)
Query: 25 PNNHEVHIY-EKSGAKWTKVHELKEHNG--QVTGIDWAPESNRIVTCGTDRNAYVWTLKG 81
P N E + E++GA HE+ H+ ++ G P + V G + ++
Sbjct: 135 PKNREATVNGEENGA-----HEINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICA--- 186
Query: 82 RTWKPTLVILRINRAARCVR-WAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR 140
W P +L R W NEN GS V+ C E +D P
Sbjct: 187 --WNPVSDLLASGSGDSTARIWNLNENSNG-GSTQLVLRHCIREGGHD--------VPSN 235
Query: 141 STVLSLDWHPNNVLLAAGSCDFKCRIFS 168
V SLDW+ + LLA GS D RI++
Sbjct: 236 KDVTSLDWNSDGTLLAMGSYDGFARIWT 263
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/191 (21%), Positives = 75/191 (39%), Gaps = 26/191 (13%)
Query: 43 VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRW 102
V + H +V I W P + +C D +W++K L ++ ++W
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDL--QAHSKEIYTIKW 409
Query: 103 APNENKFAVGSGSRVISICYFEQENDWW-----VCKHIKKPIRSTVLSLDWHPNNVLLAA 157
+P + + S +++ F+ W VC H + V S+ + P+ LA+
Sbjct: 410 SPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 158 GSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAW 217
GS D I++ T GS + S G + VC++A G +V
Sbjct: 470 GSFDKYVHIWN------------TQSGS-------LVHSYQGTGGIFEVCWNARGDKVGA 510
Query: 218 VSHDSTVCLAD 228
+ D +VC+ D
Sbjct: 511 SASDGSVCVLD 521
Score = 48.9 bits (115), Expect = 7e-06
Identities = 56/247 (22%), Positives = 94/247 (38%), Gaps = 50/247 (20%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WT+ L +H G + + W + N +++ G D+ +W T +
Sbjct: 255 YDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIW--DAHTGEAKQ 312
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR---STVLS 145
+ A V W N FA S I +C C H K + + V +
Sbjct: 313 QFPFHSAPALDVDW-QNNMTFASCSTDMCIHVCRLG-------CDHPVKTFQGHTNEVNA 364
Query: 146 LDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFGELM 193
+ W P+ +LLA+ S D +I+S A+ KE+ + +PT + P +M
Sbjct: 365 IKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIM 424
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
S+ S DSTV L D ++ + TL P+ ++ F D
Sbjct: 425 LASA---------------------SFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPD 463
Query: 254 NSLVAAG 260
+A+G
Sbjct: 464 GKYLASG 470
Score = 38.5 bits (88), Expect = 0.010
Identities = 41/148 (27%), Positives = 59/148 (39%), Gaps = 23/148 (15%)
Query: 25 PNNHEVHIY-EKSGAKWTKVHELKEHNG--QVTGIDWAPESNRIVTCGTDRNAYVWTLKG 81
P N E + E++GA HE+ H+ ++ G P + V G + ++
Sbjct: 135 PKNREATVNGEENGA-----HEINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICA--- 186
Query: 82 RTWKPTLVILRINRAARCVR-WAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR 140
W P +L R W NEN GS V+ C E +D P
Sbjct: 187 --WNPVSDLLASGSGDSTARIWNLNENSNG-GSTQLVLRHCIREGGHD--------VPSN 235
Query: 141 STVLSLDWHPNNVLLAAGSCDFKCRIFS 168
V SLDW+ + LLA GS D RI++
Sbjct: 236 KDVTSLDWNSDGTLLAMGSYDGFARIWT 263
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 50.8 bits (120), Expect = 2e-06
Identities = 42/191 (21%), Positives = 75/191 (39%), Gaps = 26/191 (13%)
Query: 43 VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRW 102
V + H +V I W P + +C D +W++K L ++ ++W
Sbjct: 352 VKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDL--QAHSKEIYTIKW 409
Query: 103 APNENKFAVGSGSRVISICYFEQENDWW-----VCKHIKKPIRSTVLSLDWHPNNVLLAA 157
+P + + S +++ F+ W VC H + V S+ + P+ LA+
Sbjct: 410 SPTGPATSNPNSSIMLASASFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPDGKYLAS 469
Query: 158 GSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAW 217
GS D I++ T GS + S G + VC++A G +V
Sbjct: 470 GSFDKYVHIWN------------TQSGS-------LVHSYQGTGGIFEVCWNARGDKVGA 510
Query: 218 VSHDSTVCLAD 228
+ D +VC+ D
Sbjct: 511 SASDGSVCVLD 521
Score = 48.9 bits (115), Expect = 7e-06
Identities = 56/247 (22%), Positives = 94/247 (38%), Gaps = 50/247 (20%)
Query: 33 YEKSGAKWTK----VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
Y+ WT+ L +H G + + W + N +++ G D+ +W T +
Sbjct: 255 YDGFARIWTENGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTIIW--DAHTGEAKQ 312
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR---STVLS 145
+ A V W N FA S I +C C H K + + V +
Sbjct: 313 QFPFHSAPALDVDW-QNNMTFASCSTDMCIHVCRLG-------CDHPVKTFQGHTNEVNA 364
Query: 146 LDWHPNNVLLAAGSCDFKCRIFS-----------AYIKEVEE-RPAPTPWGSKMPFGELM 193
+ W P+ +LLA+ S D +I+S A+ KE+ + +PT + P +M
Sbjct: 365 IKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIM 424
Query: 194 FESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITD 253
S+ S DSTV L D ++ + TL P+ ++ F D
Sbjct: 425 LASA---------------------SFDSTVRLWDVEQGVCTHTLMKHQEPVYSVAFSPD 463
Query: 254 NSLVAAG 260
+A+G
Sbjct: 464 GKYLASG 470
Score = 38.5 bits (88), Expect = 0.010
Identities = 41/148 (27%), Positives = 59/148 (39%), Gaps = 23/148 (15%)
Query: 25 PNNHEVHIY-EKSGAKWTKVHELKEHNG--QVTGIDWAPESNRIVTCGTDRNAYVWTLKG 81
P N E + E++GA HE+ H+ ++ G P + V G + ++
Sbjct: 135 PKNREATVNGEENGA-----HEINNHSKPMEIDGDVEIPPNKATVLRGHESEVFICA--- 186
Query: 82 RTWKPTLVILRINRAARCVR-WAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIR 140
W P +L R W NEN GS V+ C E +D P
Sbjct: 187 --WNPVSDLLASGSGDSTARIWNLNENSNG-GSTQLVLRHCIREGGHD--------VPSN 235
Query: 141 STVLSLDWHPNNVLLAAGSCDFKCRIFS 168
V SLDW+ + LLA GS D RI++
Sbjct: 236 KDVTSLDWNSDGTLLAMGSYDGFARIWT 263
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/219 (18%), Positives = 84/219 (38%), Gaps = 24/219 (10%)
Query: 42 KVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVR 101
K E K H V +D++ + + T D++ VW++ + + +L R RC +
Sbjct: 94 KFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYSLY--RHTHWVRCAK 151
Query: 102 WAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCD 161
++P+ S + I I + C + +D++P+ +A+ D
Sbjct: 152 FSPDGRLIVSCSEDKTIKIWDTTNKQ----CVNNFSDSVGFANFVDFNPSGTCIASAGSD 207
Query: 162 FKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHD 221
+++ + + L+ G V+ + F SG+ + S D
Sbjct: 208 QTVKVWDVRVNK------------------LLQHYQVHSGGVNCISFHPSGNYLITASSD 249
Query: 222 STVCLADADKKMAVATLASETLPLVALTFITDNSLVAAG 260
T+ + D + + TL T P+ ++F L A+G
Sbjct: 250 GTLKILDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288
Score = 40.0 bits (92), Expect = 0.003
Identities = 38/191 (19%), Positives = 69/191 (36%), Gaps = 28/191 (14%)
Query: 47 KEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLK--GRTWKPTLVILRINRAARCVRWAP 104
K H +T +D +P ++ T D +W K R ++ + V+++P
Sbjct: 15 KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYR----YVGHKDVVTSVQFSP 70
Query: 105 NENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKC 164
+ N A S R + + ++ + K P+R S+D+ + LA S D
Sbjct: 71 HGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVR----SVDFSADGQFLATASEDKSI 126
Query: 165 RIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTV 224
+++S Y + ++ WV FS G + S D T+
Sbjct: 127 KVWSMYRQ------------------RFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTI 168
Query: 225 CLADADKKMAV 235
+ D K V
Sbjct: 169 KIWDTTNKQCV 179
Score = 29.3 bits (64), Expect = 5.9
Identities = 18/60 (30%), Positives = 28/60 (46%)
Query: 203 VHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATLASETLPLVALTFITDNSLVAAGHD 262
V V FS G+ +A S D TV L DK+ + + T P+ ++ F D +A +
Sbjct: 63 VTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASE 122
>gi|9257257 WD repeat-containing protein 1 isoform 1 [Homo sapiens]
Length = 606
Score = 43.1 bits (100), Expect = 4e-04
Identities = 45/187 (24%), Positives = 75/187 (40%), Gaps = 20/187 (10%)
Query: 34 EKSGAKW-----TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTL 88
EK GA + + V E+ HN + +D + G+D N + +G +K
Sbjct: 125 EKFGAVFLWDSGSSVGEITGHNKVINSVDIKQSRPYRLATGSDDNCAAF-FEGPPFKFKF 183
Query: 89 VILRINRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCK-HIKKPIRSTVLSLD 147
I +R CVR++P+ N+FA S I I ++ + VC K + ++
Sbjct: 184 TIGDHSRFVNCVRFSPDGNRFATASADGQIYI--YDGKTGEKVCALGGSKAHDGGIYAIS 241
Query: 148 WHPNNVLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWV--HG 205
W P++ L + S D +I+ + V S P G + + C W H
Sbjct: 242 WSPDSTHLLSASGDKTSKIWDVSVNSVV---------STFPMGSTVLDQQLGCLWQKDHL 292
Query: 206 VCFSASG 212
+ S SG
Sbjct: 293 LSVSLSG 299
Score = 38.5 bits (88), Expect = 0.010
Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 17 DRTQIAICPNNHEVHIYE-KSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
D + A + +++IY+ K+G K + K H+G + I W+P+S +++ D+ +
Sbjct: 200 DGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSK 259
Query: 76 VW 77
+W
Sbjct: 260 IW 261
Score = 32.7 bits (73), Expect = 0.54
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Query: 17 DRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYV 76
D +A+C + V ++ + +++ + H+ ++ + W+P++ + G D YV
Sbjct: 500 DGAFLAVCDASKVVTVFSVADG-YSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYV 558
Query: 77 WTL 79
WTL
Sbjct: 559 WTL 561
Score = 30.4 bits (67), Expect = 2.7
Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
Query: 60 PESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI- 118
P + + G D N ++++ G T K +L V ++ + AV S+V+
Sbjct: 455 PGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVT 514
Query: 119 --SICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFS 168
S+ EN+ + H K ++ L W P+N A+G D +++
Sbjct: 515 VFSVADGYSENNVFYGHHAK------IVCLAWSPDNEHFASGGMDMMVYVWT 560
>gi|46409657 WD repeat domain 56 [Homo sapiens]
Length = 777
Score = 43.1 bits (100), Expect = 4e-04
Identities = 33/132 (25%), Positives = 59/132 (44%), Gaps = 10/132 (7%)
Query: 42 KVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVR 101
KV + K H+G + +DW ++ I++ G D VW GR P V
Sbjct: 180 KVLQWKAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGR---PLYNSQPHEHPITSVA 236
Query: 102 WAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCD 161
WAP+ FAVGS + +C + W ++KP ++ ++ W + + AG+C
Sbjct: 237 WAPDGELFAVGS-FHTLRLC---DKTGWSYA--LEKPNTGSIFNIAWSIDGTQI-AGACG 289
Query: 162 FKCRIFSAYIKE 173
+F+ +++
Sbjct: 290 NGHVVFAHVVEQ 301
Score = 38.5 bits (88), Expect = 0.010
Identities = 54/228 (23%), Positives = 90/228 (39%), Gaps = 31/228 (13%)
Query: 7 WMSRRRGRVKDRTQ---IAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESN 63
W + G VK +TQ + ++ + H+ K G V + H G V W E
Sbjct: 64 WFPKSLG-VKKQTQAESFVLTSSDGKFHLISKLGRVEKSV---EAHCGAVLAGRWNYEGT 119
Query: 64 RIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI--SIC 121
+VT G D +W+ G + TL + V W P+ K +G ++I +
Sbjct: 120 ALVTVGEDGQIKIWSKTGML-RSTLA--QQGTPVYSVAWGPDSEKVLYTAGKQLIIKPLQ 176
Query: 122 YFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEV-EERPAP 180
+ W K +L +DW+ N L+ + D K +++ +Y + + +P
Sbjct: 177 PNAKVLQW-------KAHDGIILKVDWNSVNDLILSAGEDCKYKVWDSYGRPLYNSQPHE 229
Query: 181 TPWGSK--MPFGELM----FESSSSC---GWVHGVCFSASGS--RVAW 217
P S P GEL F + C GW + + +GS +AW
Sbjct: 230 HPITSVAWAPDGELFAVGSFHTLRLCDKTGWSYALEKPNTGSIFNIAW 277
>gi|34996489 pleckstrin homology domain interacting protein [Homo
sapiens]
Length = 1821
Score = 42.7 bits (99), Expect = 5e-04
Identities = 21/69 (30%), Positives = 34/69 (49%)
Query: 21 IAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLK 80
+A +H + +Y + K+ EL+ H +V I ++ SNR V+ D A +W K
Sbjct: 336 LATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFK 395
Query: 81 GRTWKPTLV 89
R WK L+
Sbjct: 396 RREWKSILL 404
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 42.4 bits (98), Expect = 7e-04
Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 4/121 (3%)
Query: 49 HNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENK 108
H G V + AP++ V+ D +A +W ++ + T + A C + PN N
Sbjct: 183 HTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAIC--FFPNGNA 240
Query: 109 FAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFS 168
FA GS + F+ D + + I + S+ + + LL AG DF C ++
Sbjct: 241 FATGSDDATCRL--FDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWD 298
Query: 169 A 169
A
Sbjct: 299 A 299
Score = 38.9 bits (89), Expect = 0.007
Identities = 49/233 (21%), Positives = 89/233 (38%), Gaps = 39/233 (16%)
Query: 42 KVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRA----- 96
KVH + + V +AP N + G D ++ LK R +R++R
Sbjct: 89 KVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGN-----VRVSRELAGHT 143
Query: 97 --ARCVRWAPNENKFAVGSGSRVISICYFEQ-ENDWWVCKHIKKPIRSTVLSLDWHPNNV 153
C R+ ++N+ SG ++ E + H V+SL P+
Sbjct: 144 GYLSCCRFL-DDNQIVTSSGDTTCALWDIETGQQTTTFTGH-----TGDVMSLSLAPDTR 197
Query: 154 LLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGS 213
L +G+CD ++ W + F S ++ +CF +G+
Sbjct: 198 LFVSGACDASAKL----------------WDVREGMCRQTFTGHESD--INAICFFPNGN 239
Query: 214 RVAWVSHDSTVCLAD--ADKKMAVATLASETLPLVALTFITDNSLVAAGHDCF 264
A S D+T L D AD+++ + + + +++F L+ AG+D F
Sbjct: 240 AFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292
>gi|118402582 cell division cycle 20 [Homo sapiens]
Length = 499
Score = 42.0 bits (97), Expect = 9e-04
Identities = 39/141 (27%), Positives = 56/141 (39%), Gaps = 22/141 (15%)
Query: 26 NNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVW-TLKGR-T 83
++H+V + E V L H+ +V G+ WAP+ + + G D VW + G
Sbjct: 291 HHHDVRVAEHH------VATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGG 344
Query: 84 WKPTLVILRINRAARCVRWAP-NENKFAVGSGS--RVISICYFEQENDWWVCKHI---KK 137
W P + A + V W P N A G G+ R I I W VC
Sbjct: 345 WVPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRI--------WNVCSGACLSAV 396
Query: 138 PIRSTVLSLDWHPNNVLLAAG 158
S V S+ W P+ L +G
Sbjct: 397 DAHSQVCSILWSPHYKELISG 417
>gi|55769546 PAK1 interacting protein 1 [Homo sapiens]
Length = 392
Score = 42.0 bits (97), Expect = 9e-04
Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 5/74 (6%)
Query: 39 KWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTL-KGRTWKPTLVILRINRAA 97
KW + +K H GQVT + P ++ GTD+ W L +GR + I I + A
Sbjct: 112 KWECLKSIKAHKGQVTFLSIHPSGKLALSVGTDKTLRTWNLVEGR----SAFIKNIKQNA 167
Query: 98 RCVRWAPNENKFAV 111
V W+P ++ V
Sbjct: 168 HIVEWSPRGEQYVV 181
Score = 32.7 bits (73), Expect = 0.54
Identities = 33/154 (21%), Positives = 60/154 (38%), Gaps = 13/154 (8%)
Query: 39 KWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAAR 98
+WT V + H + A S +VT D +++ +K + LV +
Sbjct: 29 QWTLVADFTHHAHTASLSAVAVNSRFVVTGSKDETIHIYDMKKKIEHGALV--HHSGTIT 86
Query: 99 CVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAG 158
C+++ N + SG+ IC ++ + W C K + V L HP+ L +
Sbjct: 87 CLKFYGNRHLI---SGAEDGLICIWDAKK--WECLKSIKAHKGQVTFLSIHPSGKLALSV 141
Query: 159 SCDFKCRIF------SAYIKEVEERPAPTPWGSK 186
D R + SA+IK +++ W +
Sbjct: 142 GTDKTLRTWNLVEGRSAFIKNIKQNAHIVEWSPR 175
>gi|22749037 WD repeat domain 65 [Homo sapiens]
Length = 698
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 26 NNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWK 85
N + +H+Y + + + LK H G++ I W + +++++ GTD Y W L T K
Sbjct: 490 NGNVIHVYTTTSLE--NISSLKGHTGKIRSIVWNADDSKLISGGTDGAVYEWNLS--TGK 545
Query: 86 PTLVILRINRAARCVRWAPNEN-KFAVGS 113
+ + + CV +P+ FAVGS
Sbjct: 546 RETECVLKSCSYNCVTVSPDAKIIFAVGS 574
>gi|58331266 WD repeat domain 59 [Homo sapiens]
Length = 974
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/139 (25%), Positives = 64/139 (46%), Gaps = 9/139 (6%)
Query: 26 NNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAP-ESNRIVTCGTDRNAYVWTLKGRTW 84
+N V +Y+ L+ H ++ +DWA E + +VT D Y+W +K T
Sbjct: 81 SNQRVDLYKWKDGSGEVGTTLQGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKD-TR 139
Query: 85 KPTLVILRINRAARCVRW-APNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTV 143
KPT+ + + A++ V+W N N A + +++ +++ + S +
Sbjct: 140 KPTVALSAVAGASQ-VKWNKKNANCLATSHDG---DVRIWDKRKPSTAVEYLAAHL-SKI 194
Query: 144 LSLDWHPNNV-LLAAGSCD 161
LDWHP++ +LA S D
Sbjct: 195 HGLDWHPDSEHILATSSQD 213
Score = 29.6 bits (65), Expect = 4.5
Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 2/50 (4%)
Query: 29 EVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIV-TCGTDRNAYVW 77
+V I++K T V L H ++ G+DW P+S I+ T D + W
Sbjct: 171 DVRIWDKRKPS-TAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFW 219
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 40.8 bits (94), Expect = 0.002
Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 23/215 (10%)
Query: 46 LKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPN 105
LK H +T + + +T DR +W TL R N P
Sbjct: 88 LKAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHR-NVVYAIAFNNPY 146
Query: 106 ENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCR 165
+K A GS + + E C H + + ++ L ++P + L+A GS D +
Sbjct: 147 GDKIATGSFDKTCKLWSVETGK----CYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAK 202
Query: 166 IFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVC 225
++ + GE ++ + + F+ SG R+ S D TV
Sbjct: 203 LWD------------------IQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTVV 244
Query: 226 LADADKKMAVATLASETLPLVALTFITDNSLVAAG 260
+ DAD V L + + +F D SL+ G
Sbjct: 245 VWDADTGRKVNILIGHCAEISSASFNWDCSLILTG 279
Score = 32.0 bits (71), Expect = 0.91
Identities = 10/35 (28%), Positives = 23/35 (65%)
Query: 43 VHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVW 77
+ +L+ H G+++ I + P+ N ++T +D+ A +W
Sbjct: 338 IAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIW 372
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 20/145 (13%)
Query: 41 TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRN-AYVWTL-KGRTWKPTLVILRINRAAR 98
T V+ + G + + WAP + GT RN A++W + KG+ +I R N
Sbjct: 403 TAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGK------IIQRFNEHGT 456
Query: 99 ----CVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNV- 153
C+ W+ ++K S I + D V K P + V DW NN
Sbjct: 457 NGIFCIAWSHKDSKRIATCSSDGFCII---RTIDGKVLHKYKHP--AAVFGCDWSQNNKD 511
Query: 154 LLAAGSCDFKCRIFSAYIKEVEERP 178
++A G D R++ Y+ ++P
Sbjct: 512 MIATGCEDTNVRVY--YVATSSDQP 534
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 39.3 bits (90), Expect = 0.006
Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 20/145 (13%)
Query: 41 TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRN-AYVWTL-KGRTWKPTLVILRINRAAR 98
T V+ + G + + WAP + GT RN A++W + KG+ +I R N
Sbjct: 427 TAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGK------IIQRFNEHGT 480
Query: 99 ----CVRWAPNENKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNV- 153
C+ W+ ++K S I + D V K P + V DW NN
Sbjct: 481 NGIFCIAWSHKDSKRIATCSSDGFCII---RTIDGKVLHKYKHP--AAVFGCDWSQNNKD 535
Query: 154 LLAAGSCDFKCRIFSAYIKEVEERP 178
++A G D R++ Y+ ++P
Sbjct: 536 MIATGCEDTNVRVY--YVATSSDQP 558
>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
Length = 943
Score = 38.9 bits (89), Expect = 0.007
Identities = 39/169 (23%), Positives = 69/169 (40%), Gaps = 26/169 (15%)
Query: 20 QIAIC----PNNHEVHIYEKSG-------AKWTKVHELKEHNGQVTGIDWAPESNRIVTC 68
+ A+C P + +V I K+G A + + H+G + + +P+ VT
Sbjct: 455 EYALCSFFVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTG 514
Query: 69 GTDRNAYVW----------TLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI 118
G D++ W T K + K T L+++ CV ++PN+ AV +
Sbjct: 515 GADKSVKFWDFELVKDENSTQKRLSVKQTRT-LQLDEDVLCVSYSPNQKLLAVSLLDCTV 573
Query: 119 SICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIF 167
I Y + + K P V+ +D + L+A GS D +I+
Sbjct: 574 KIFYVDTLKFFLSLYGHKLP----VICMDISHDGALIATGSADRNVKIW 618
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 38.9 bits (89), Expect = 0.007
Identities = 50/223 (22%), Positives = 84/223 (37%), Gaps = 35/223 (15%)
Query: 49 HNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENK 108
H V +D +P S + DR A +W+ RT+ P + CV++ PN N
Sbjct: 383 HAYPVWDLDISPYSLYFASGSHDRTARLWSFD-RTY-PLRIYAGHLADVDCVKFHPNSNY 440
Query: 109 FAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFS 168
A GS + + + +Q N + R VLSL + PN LA+ D + +++
Sbjct: 441 LATGSTDKTVRLWSAQQGNS----VRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWD 496
Query: 169 AYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTV---- 224
+ G L E + + FS +A S D++V
Sbjct: 497 ------------------LASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWD 538
Query: 225 -----CLADADKKMA--VATLASETLPLVALTFITDNSLVAAG 260
C A AD + V + ++++ F+ N L+ G
Sbjct: 539 IRNTYCSAPADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTG 581
Score = 38.1 bits (87), Expect = 0.013
Identities = 50/220 (22%), Positives = 86/220 (39%), Gaps = 26/220 (11%)
Query: 41 TKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCV 100
T++ L+ H G V + +S+ +++C D + W L T T++ +
Sbjct: 333 TEMKILRGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFT--NTVLYQGHAYPVWDL 390
Query: 101 RWAPNENKFAVGSGSRVISICYFEQENDWWV-CKHIKKPIRSTVLSLDWHPNNVLLAAGS 159
+P FA GS R + F++ + H+ + V + +HPN+ LA GS
Sbjct: 391 DISPYSLYFASGSHDRTARLWSFDRTYPLRIYAGHL-----ADVDCVKFHPNSNYLATGS 445
Query: 160 CDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVS 219
D R++SA G + + G V + FS +G +A
Sbjct: 446 TDKTVRLWSA------------------QQGNSVRLFTGHRGPVLSLAFSPNGKYLASAG 487
Query: 220 HDSTVCLADADKKMAVATLASETLPLVALTFITDNSLVAA 259
D + L D L T + +LTF D+ L+A+
Sbjct: 488 EDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIAS 527
Score = 30.8 bits (68), Expect = 2.0
Identities = 12/43 (27%), Positives = 22/43 (51%)
Query: 38 AKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYVWTLK 80
A T EL+ H +T + ++P+S I + D + VW ++
Sbjct: 498 ASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIR 540
>gi|53729352 WD repeat-containing protein 1 isoform 2 [Homo sapiens]
Length = 466
Score = 38.5 bits (88), Expect = 0.010
Identities = 16/62 (25%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 17 DRTQIAICPNNHEVHIYE-KSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAY 75
D + A + +++IY+ K+G K + K H+G + I W+P+S +++ D+ +
Sbjct: 60 DGNRFATASADGQIYIYDGKTGEKVCALGGSKAHDGGIYAISWSPDSTHLLSASGDKTSK 119
Query: 76 VW 77
+W
Sbjct: 120 IW 121
Score = 35.0 bits (79), Expect = 0.11
Identities = 30/122 (24%), Positives = 50/122 (40%), Gaps = 14/122 (11%)
Query: 94 NRAARCVRWAPNENKFAVGSGSRVISICYFEQENDWWVCK-HIKKPIRSTVLSLDWHPNN 152
+R CVR++P+ N+FA S I I ++ + VC K + ++ W P++
Sbjct: 49 SRFVNCVRFSPDGNRFATASADGQIYI--YDGKTGEKVCALGGSKAHDGGIYAISWSPDS 106
Query: 153 VLLAAGSCDFKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWV--HGVCFSA 210
L + S D +I+ + V S P G + + C W H + S
Sbjct: 107 THLLSASGDKTSKIWDVSVNSVV---------STFPMGSTVLDQQLGCLWQKDHLLSVSL 157
Query: 211 SG 212
SG
Sbjct: 158 SG 159
Score = 32.7 bits (73), Expect = 0.54
Identities = 14/63 (22%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Query: 17 DRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDWAPESNRIVTCGTDRNAYV 76
D +A+C + V ++ + +++ + H+ ++ + W+P++ + G D YV
Sbjct: 360 DGAFLAVCDASKVVTVFSVADG-YSENNVFYGHHAKIVCLAWSPDNEHFASGGMDMMVYV 418
Query: 77 WTL 79
WTL
Sbjct: 419 WTL 421
Score = 30.4 bits (67), Expect = 2.7
Identities = 25/112 (22%), Positives = 47/112 (41%), Gaps = 9/112 (8%)
Query: 60 PESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI- 118
P + + G D N ++++ G T K +L V ++ + AV S+V+
Sbjct: 315 PGGDTVAIGGVDGNVRLYSILGTTLKDEGKLLEAKGPVTDVAYSHDGAFLAVCDASKVVT 374
Query: 119 --SICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFS 168
S+ EN+ + H K ++ L W P+N A+G D +++
Sbjct: 375 VFSVADGYSENNVFYGHHAK------IVCLAWSPDNEHFASGGMDMMVYVWT 420
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,234,790
Number of Sequences: 37866
Number of extensions: 609116
Number of successful extensions: 2105
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 1592
Number of HSP's gapped (non-prelim): 469
length of query: 370
length of database: 18,247,518
effective HSP length: 104
effective length of query: 266
effective length of database: 14,309,454
effective search space: 3806314764
effective search space used: 3806314764
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.