Search of human proteins with 88999601

Search of human proteins with 88999601

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|88999601 tripartite motif-containing 69 isoform a [Homo
sapiens]
         (500 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]  1035   0.0  
gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]   689   0.0  
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   271   1e-72
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   257   2e-68
gi|217035095 tripartite motif-containing 62 [Homo sapiens]            236   4e-62
gi|5730009 ret finger protein [Homo sapiens]                          216   4e-56
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             211   1e-54
gi|30023818 tripartite motif protein 50A [Homo sapiens]               210   2e-54
gi|37622899 ring finger protein 137 [Homo sapiens]                    210   3e-54
gi|22749269 ring finger protein 129 [Homo sapiens]                    207   1e-53
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    206   3e-53
gi|15208660 tripartite motif protein 21 [Homo sapiens]                201   1e-51
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            199   4e-51
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             199   6e-51
gi|5454014 tripartite motif-containing 38 [Homo sapiens]              193   3e-49
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            190   3e-48
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   185   1e-46
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    184   2e-46
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    184   2e-46
gi|56605981 tripartite motif-containing 72 [Homo sapiens]             181   1e-45
gi|4557743 Mediterranean fever protein [Homo sapiens]                 174   2e-43
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   174   2e-43
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    174   2e-43
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   172   6e-43
gi|63054855 erythroblast membrane-associated protein precursor [...   171   1e-42
gi|19923536 erythroblast membrane-associated protein precursor [...   171   1e-42
gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]   166   3e-41
gi|149193331 tripartite motif protein 15 [Homo sapiens]               161   1e-39
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      158   1e-38
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      158   1e-38

>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score = 1035 bits (2675), Expect = 0.0
 Identities = 500/500 (100%), Positives = 500/500 (100%)

Query: 1   MEVSTNPSSNIDPGDYVEMNDSITHLPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNF 60
           MEVSTNPSSNIDPGDYVEMNDSITHLPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNF
Sbjct: 1   MEVSTNPSSNIDPGDYVEMNDSITHLPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNF 60

Query: 61  CEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLDKLVEKIKKLPLLKGHPQCPEHGE 120
           CEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLDKLVEKIKKLPLLKGHPQCPEHGE
Sbjct: 61  CEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLDKLVEKIKKLPLLKGHPQCPEHGE 120

Query: 121 NLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQT 180
           NLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQT
Sbjct: 121 NLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQT 180

Query: 181 LRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNL 240
           LRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNL
Sbjct: 181 LRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNL 240

Query: 241 SQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLG 300
           SQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLG
Sbjct: 241 SQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLG 300

Query: 301 QYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPER 360
           QYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPER
Sbjct: 301 QYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPER 360

Query: 361 FDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRN 420
           FDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRN
Sbjct: 361 FDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRN 420

Query: 421 QTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF 480
           QTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF
Sbjct: 421 QTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF 480

Query: 481 CPCLNDGGENKEPLHILHPQ 500
           CPCLNDGGENKEPLHILHPQ
Sbjct: 481 CPCLNDGGENKEPLHILHPQ 500


>gi|37595541 tripartite motif-containing 69 isoform b [Homo sapiens]
          Length = 341

 Score =  689 bits (1777), Expect = 0.0
 Identities = 339/339 (100%), Positives = 339/339 (100%)

Query: 162 EELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDI 221
           EELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDI
Sbjct: 3   EELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLHSKEKDI 62

Query: 222 LTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLE 281
           LTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLE
Sbjct: 63  LTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITTLLHSLE 122

Query: 282 QGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKS 341
           QGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKS
Sbjct: 123 QGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKS 182

Query: 342 QTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIR 401
           QTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIR
Sbjct: 183 QTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIR 242

Query: 402 KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKT 461
           KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKT
Sbjct: 243 KGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKT 302

Query: 462 MTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 500
           MTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ
Sbjct: 303 MTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 341


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  271 bits (693), Expect = 1e-72
 Identities = 159/473 (33%), Positives = 252/473 (53%), Gaps = 13/473 (2%)

Query: 32  IQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCT 91
           ++++ +E  C +C ++ ++P+++ CGHNFC+ACI  +W    ++  CP C+   +Y +  
Sbjct: 20  LENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLR 79

Query: 92  FNPVLDKLVEKIKKLPLLK----GHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQS 147
            N  L  +VE  K+L  +K        CP+H E L LF   D + +C  C  A     ++
Sbjct: 80  PNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLIC--AISHTHRA 137

Query: 148 KEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEF 207
              + + DA   + E+L      LE  L+E+   ++ +++     K      +Q +  EF
Sbjct: 138 HTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREF 197

Query: 208 LKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSF 267
            +LH+ L  +++ +L+ L EE + + + +  N + L ++      +   ++ K   Q+ F
Sbjct: 198 EELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKC-LQSGF 256

Query: 268 DFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTL 327
           + LKD+ + L   E+   +  T   I  + N   +  P QY   R++   L   ++ +TL
Sbjct: 257 EMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNF--PRQYFALRKILKQL---IADVTL 311

Query: 328 DPKTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAK 386
           DP+TAHPNLVLS+ + SV   + + + +PD P RF     VL + GFTSG+ YWEVEV  
Sbjct: 312 DPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGD 371

Query: 387 KTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIY 446
           KT W VGV R+S+ RKG     PE G+W +RL N     A   P   L +     +VGI+
Sbjct: 372 KTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIF 431

Query: 447 LDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHP 499
           LDYE G LSFYN    +HIYTF++TF EKL+P F P +  G +N  PL I  P
Sbjct: 432 LDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPP 484


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  257 bits (656), Expect = 2e-68
 Identities = 161/501 (32%), Positives = 256/501 (51%), Gaps = 39/501 (7%)

Query: 32  IQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCT 91
           ++++ +E  C +C ++ ++P+++ CGHNFC+ACI  +W    ++  CP C+   +Y +  
Sbjct: 20  LENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLR 79

Query: 92  FNPVLDKLVEKIKKLPLLK----GHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQS 147
            N  L  +VE  K+L  +K        CP+H E L LF   D + +C  C  A     ++
Sbjct: 80  PNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEAVCLIC--AISHTHRA 137

Query: 148 KEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEF 207
              + + DA   + E+L      LE  L+E+   ++ +++     K      +Q +  EF
Sbjct: 138 HTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQQILREF 197

Query: 208 LKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSF 267
            +LH+ L  +++ +L+ L EE + + + +  N + L ++      +   ++ K   Q+ F
Sbjct: 198 EELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKC-LQSGF 256

Query: 268 DFLKDITTLL-------------------HSLEQGM-------KVLATRELISRKLNLGQ 301
           + LKD+ + L                   H    G+       + + T E+ S  + L +
Sbjct: 257 EMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKTMEVTSVSIELEK 316

Query: 302 YKG--PIQYMVWREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIK-KIMPDDP 358
                P QY   R++   L   ++ +TLDP+TAHPNLVLS+ + SV   + + + +PD P
Sbjct: 317 NFSNFPRQYFALRKILKQL---IADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTP 373

Query: 359 ERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRL 418
            RF     VL + GFTSG+ YWEVEV  KT W VGV R+S+ RKG     PE G+W +RL
Sbjct: 374 RRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRL 433

Query: 419 RNQTDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYP 478
            N     A   P   L +     +VGI+LDYE G LSFYN    +HIYTF++TF EKL+P
Sbjct: 434 WNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFTDTFTEKLWP 493

Query: 479 YFCPCLNDGGENKEPLHILHP 499
            F P +  G +N  PL I  P
Sbjct: 494 LFYPGIRAGRKNAAPLTIRPP 514


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  236 bits (602), Expect = 4e-62
 Identities = 149/469 (31%), Positives = 232/469 (49%), Gaps = 16/469 (3%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETF--CPECKMLCQYNNCTFNPV 95
           EL C +C   ++DP+ L C H FC  CI + W  Q  +    CPEC+          +  
Sbjct: 8   ELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPALAPSLK 67

Query: 96  LDKLVEKIKKLPL------LKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKE 149
           L  +VE+    PL       +    C  H + +KLF   D  L+CF C +  L   +  +
Sbjct: 68  LANIVERYSSFPLDAILNARRAARPCQAH-DKVKLFCLTDRALLCFFCDEPALH--EQHQ 124

Query: 150 FLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLK 209
              I DA      EL  Q   L+ + +E      + K  +A  K +   L+  +   F +
Sbjct: 125 VTGIDDAFDELQRELKDQLQALQDSEREHTEALQLLKRQLAETKSSTKSLRTTIGEAFER 184

Query: 210 LHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDF 269
           LH+ L  ++K +L EL  +      ++E  + +  +Q    ++    +Q +  + +   F
Sbjct: 185 LHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQERLAETDRHTF 244

Query: 270 LKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDP 329
           L  + +L   L+   K+  T  L        +Y GP+QY +W+ +   + P  + LTLDP
Sbjct: 245 LAGVASLSERLKG--KIHETN-LTYEDFPTSKYTGPLQYTIWKSLFQDIHPVPAALTLDP 301

Query: 330 KTAHPNLVLSKSQTSVWHGDIK-KIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKT 388
            TAH  L+LS   T V +G++  + + D P+RFD  V+VLGS  F+SG  YWEV VA+KT
Sbjct: 302 GTAHQRLILSDDCTIVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKT 361

Query: 389 KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLD 448
           +W +G+  E+  RKGS  + P +GF+ + + +     A   P   L + + LDKVG++LD
Sbjct: 362 QWVIGLAHEAASRKGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLD 421

Query: 449 YEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLND-GGENKEPLHI 496
           Y+ G L FYNA  M+ +YTF   F  KL  YF P  +   G+N +PL I
Sbjct: 422 YDQGLLIFYNADDMSWLYTFREKFPGKLCSYFSPGQSHANGKNVQPLRI 470


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  216 bits (550), Expect = 4e-56
 Identities = 152/496 (30%), Positives = 246/496 (49%), Gaps = 32/496 (6%)

Query: 26  LPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLC 85
           + S  V + +  E  CP+C  +F +P+ML CGHN C AC+   W        CP+C+   
Sbjct: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETF 60

Query: 86  QYNNCTFNPVLDKLVEKIKKL----PLLKGHPQ--CPEHGENLKLFSKPDGKLICFQCKD 139
              +   N  L  + + +K+L    P   G     C +H E LKL+ + D   IC  C  
Sbjct: 61  PQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPICVVCDR 120

Query: 140 ARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHL 199
           +R   G S   L + +AV  F E++  Q   L+  +K+L+  R  Q E   A   +   +
Sbjct: 121 SREHRGHS--VLPLEEAVEGFKEQIQNQLDHLKR-VKDLKKRRRAQGEQARAELLSLTQM 177

Query: 200 QQH-VSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQ 258
           ++  +  EF +L+  L   E  +L  L E   A+   +   ++Q          ++  ++
Sbjct: 178 EREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIAQLE 237

Query: 259 AKTEQQNSFDFLKDITTLLH---------------SLEQGMKVLATRELISRKLNLGQYK 303
            K +QQ + + L+DI   L                 L++ + + A + L   + +L Q+ 
Sbjct: 238 EK-QQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTE-SLKQFT 295

Query: 304 GPIQYMVWR--EMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERF 361
             +Q  + +  E+++     +  +TLDP TA+P+L+LS +   V +  +++ +PD+PERF
Sbjct: 296 EKMQSDMEKIQELREAQLYSVD-VTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERF 354

Query: 362 DSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQ 421
           +    VLGS  F +G+ YWEVEV  K KWT+GV  +S+ RKG     P+ GFW + L   
Sbjct: 355 NLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYG 414

Query: 422 TDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYF 480
            +  AL  P  +L L   L +VGI+LDY+ G++SFYN     H +TFS+ TF   + PYF
Sbjct: 415 KEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474

Query: 481 CPCLNDGGENKEPLHI 496
               + GG++  PL I
Sbjct: 475 SLSYS-GGKSAAPLII 489


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  211 bits (537), Expect = 1e-54
 Identities = 148/473 (31%), Positives = 237/473 (50%), Gaps = 24/473 (5%)

Query: 31  VIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNC 90
           +++++  EL C +C D+F  P+   CGH+FC  C+   W        CPEC    +  + 
Sbjct: 6   LMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHF 65

Query: 91  TFNPVLDKLVEKIKKL--PLLKGHPQCPEHGE---NLKLFSKPDGKLICFQCKDARLSVG 145
             N  L +L    ++L   +L+   +   +G      K  S  +     F  +    S G
Sbjct: 66  QSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQ----SHG 121

Query: 146 QSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSM 205
            ++  L  S+A     E+L      L    KE Q +   +KE +   +E     +Q V  
Sbjct: 122 ANRVHLS-SEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVS 180

Query: 206 EFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQN 265
           E++K+HQFL  +E+  L  L +E K    ++  N  +L +Q      M+  I++ + Q +
Sbjct: 181 EYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSS-QSS 239

Query: 266 SFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPL 325
           +F+ L+++   L   E    +L   E  + +L+L +  G         M++ L    + +
Sbjct: 240 AFESLEEVRGALERSEP--LLLQCPEATTTELSLCRITG---------MKEMLRKFSTEI 288

Query: 326 TLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVA 385
           TLDP TA+  LVLS+   SV +G  ++ +PD+PERFD S  VLG++ FTSG+ YWEVEV 
Sbjct: 289 TLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVG 348

Query: 386 KKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKA-LDLPSFSLTLTNNLDKVG 444
            KT+W VG+ ++S+ RKG+ P  P   F L+ L+   D    +  P     +   + KVG
Sbjct: 349 NKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVG 408

Query: 445 IYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPLHI 496
           ++LDYE G ++FYN    + IY+F   +F E L P F PCL + G N +PL I
Sbjct: 409 VFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTI 461


>gi|30023818 tripartite motif protein 50A [Homo sapiens]
          Length = 487

 Score =  210 bits (535), Expect = 2e-54
 Identities = 143/478 (29%), Positives = 220/478 (46%), Gaps = 35/478 (7%)

Query: 39  LHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLDK 98
           L CP+C + F++PLML CGH++C+ C+         E  CP C+     ++   N  L +
Sbjct: 14  LQCPICLEVFKEPLMLQCGHSYCKGCLVSLSCHLDAELRCPVCRQAVDGSSSLPNVSLAR 73

Query: 99  LVEKIKKLPLLKGHPQ---CPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISD 155
           ++E ++    L G P+   C  H   L LF + D +LIC  C    L   Q      +S 
Sbjct: 74  VIEALR----LPGDPEPKVCVHHRNPLSLFCEKDQELICGLC--GLLGSHQHHPVTPVST 127

Query: 156 AVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQH-------VSMEFL 208
                 EELA    +L+   K++        E IA    N+  +          +  EF 
Sbjct: 128 VYSRMKEELAALISELKQEQKKVD-------ELIAKLVNNRTRIVNESDVFSWVIRREFQ 180

Query: 209 KLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 268
           +LH  +  ++   L  +    + L   +++ L Q Q      ++ L   +   EQ  + D
Sbjct: 181 ELHHLVDEEKARCLEGIGGHTRGLVASLDMQLEQAQG----TRERLAQAECVLEQFGNED 236

Query: 269 FLKDITTLLHSLEQGMKVLATRELISR----KLNLGQYKGPIQYMVWREMQDTLCPGLSP 324
             K I    HS+    ++   R L           G ++  I+  VW+ +   + P   P
Sbjct: 237 HHKFIRKF-HSMASRAEMPQARPLEGAFSPISFKPGLHQADIKLTVWKRLFRKVLPAPEP 295

Query: 325 LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEV 384
           L LDP TAHP L LSK  T V  G + +     PERFD S  VL SRGF+ G+ YWEV V
Sbjct: 296 LKLDPATAHPLLELSKGNTVVQCGLLAQRRASQPERFDYSTCVLASRGFSCGRHYWEVVV 355

Query: 385 AKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVG 444
             K+ W +GV++ +  RKG    +PE G WL+ L+     +A   P   L +  +  ++G
Sbjct: 356 GSKSDWRLGVIKGTASRKGKLNRSPEHGVWLIGLKEGRVYEAFACPRVPLPVAGHPHRIG 415

Query: 445 IYLDYEGGQLSFYNA---KTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHP 499
           +YL YE G+L+F++A     +  +YTF   F  KLYP    C ++ G N  P+ +  P
Sbjct: 416 LYLHYEQGELTFFDADRPDDLRPLYTFQADFQGKLYPILDTCWHERGSNSLPMVLPPP 473


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  210 bits (534), Expect = 3e-54
 Identities = 148/489 (30%), Positives = 244/489 (49%), Gaps = 39/489 (7%)

Query: 31  VIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKET----FCPECKMLCQ 86
           +++ I  E+ CP+C  + R+P+ + CGH+FC +C+   W +  +       CP C+   Q
Sbjct: 6   LVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPVQ 65

Query: 87  YNNCTFNPVLDKLVEKIKKLPL-----LKGHPQCPEHGENLKLFSKPDGKLICFQCKDAR 141
             N   N  L  +VEK++ L L     LKG   C  HGE LK+F K D  ++C  C  + 
Sbjct: 66  PRNLRPNWQLANVVEKVRLLRLHPGMGLKGD-LCERHGEKLKMFCKEDVLIMCEACSQS- 123

Query: 142 LSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQ 201
               ++   + + D    +  EL      L+   +E   L   +++  A  K      +Q
Sbjct: 124 -PEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVETRKQ 182

Query: 202 HVSMEFLKLHQFLHSKEKD----------ILTELREEGKALNEEMELNLSQLQEQCLLAK 251
            +  EF K  + L  K+             L  L+ E     +++ELN S+L +Q  +  
Sbjct: 183 SIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQSQVLW 242

Query: 252 DMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVW 311
            M+  ++ ++++   +  L+DI  +L+  +     L   E IS +L     K   + +  
Sbjct: 243 RMIAELKERSQRPVRW-MLQDIQEVLNRSKSWS--LQQPEPISLEL-----KTDCRVLGL 294

Query: 312 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR 371
           RE+  T     + + LDP TA+  L++S+ +  V +GD  + +PD+PERF     VLGS+
Sbjct: 295 REILKTYA---ADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQ 351

Query: 372 GFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKA--LDL 429
             +SG+ YWEVEV  +++W +GV ++++ RK    L+P  GFW++RLR   + +A   + 
Sbjct: 352 CISSGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEY 411

Query: 430 PSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTM-THIYTFSN-TFMEKLYPYFCPCLNDG 487
           P  SL +     +VGI++DYE   +SFYN     +HI+TF    F  +L PYF PC + G
Sbjct: 412 PILSLPVPPR--RVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYFSPCYSIG 469

Query: 488 GENKEPLHI 496
             N  PL I
Sbjct: 470 TNNTAPLAI 478


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  207 bits (528), Expect = 1e-53
 Identities = 137/468 (29%), Positives = 231/468 (49%), Gaps = 26/468 (5%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETF-CPECKMLCQYNNCTFNPVL 96
           E  CP+C ++ +DP+ ++CGHNFC +C+   W+    +TF CP C+    Y +   NP L
Sbjct: 13  ESSCPICLEYLKDPVTINCGHNFCRSCLSVSWK-DLDDTFPCPVCRFCFPYKSFRRNPQL 71

Query: 97  DKLVEKIKKLPLL-------KGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKE 149
             L E  K+L +        K +  C +H + L LF   D +++C QC     S    K 
Sbjct: 72  RNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEILCTQCS---FSTKHQKH 128

Query: 150 FL-QISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFL 208
           ++  I  A  +  E L      L   ++ ++ +  +Q       K+   + ++ ++ EF 
Sbjct: 129 YICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINSEFE 188

Query: 209 KLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 268
           ++  FL ++++ IL ++++E   +  ++  NL +L +     K +L  ++ K+ Q N   
Sbjct: 189 QIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVEGKSVQSNL-- 246

Query: 269 FLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLD 328
              ++ T   S+    + L   EL S +L    +  P QY     +   + P    + LD
Sbjct: 247 ---ELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYS---GLDRIIKPFQVDVILD 300

Query: 329 PKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKT 388
             TAHP L++S+ + +V +   K+ +  DP RF    AVLGS+ F+SG+ YWEVEV  K 
Sbjct: 301 LNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKP 360

Query: 389 KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLD 448
           KW +GV ++ ++R      +   GFW +    ++   A    +  L       K+GI+LD
Sbjct: 361 KWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFLD 420

Query: 449 YEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHI 496
           YE G LSFYN    + +YTF++ F E ++PYF       G + EPL I
Sbjct: 421 YELGDLSFYNMNDRSILYTFNDCFTEAVWPYFYT-----GTDSEPLKI 463


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  206 bits (525), Expect = 3e-53
 Identities = 144/480 (30%), Positives = 223/480 (46%), Gaps = 38/480 (7%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETF------------CPECKMLC 85
           E  C +C + FR+P+ + CGH+FC ACI   W      +             CP+C+   
Sbjct: 26  EATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCREPA 85

Query: 86  QYNNCTFNPVLDKLVEKIKKLPLLKGHP---------------QCPEHGENLKLFSKPDG 130
           + +    N  L  +   +++  L    P               +C +HGE  KL+ + DG
Sbjct: 86  RPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYCQDDG 145

Query: 131 KLICFQCKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIA 190
           + IC  C  AR    +    L + +AV    E L  +   L+  L++ +  R+ +K+   
Sbjct: 146 RAICVVCDRAREH--REHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKESK 203

Query: 191 AHKENKLHLQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLA 250
              +     Q+ V  EF  L  FL  +E  +L  L E  + + ++   NL+QL  +    
Sbjct: 204 ELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEITQL 263

Query: 251 KDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQ--GMKVLATRELISRKLNLGQYKGPIQY 308
             +   IQ +T Q+   DFL++  + L       G K       +  K+     K  +  
Sbjct: 264 SKLSSQIQ-ETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSLKTFVLK 322

Query: 309 MVWREMQDTLCPGLSP-----LTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDS 363
            + ++ ++ L   L       LTLDP TA+P L+LS     V  G+  + +P+ P RFD+
Sbjct: 323 GMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNHPCRFDT 382

Query: 364 SVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTD 423
           +  VL S GF+SG+ +WEVEV  K  W  GV RES+ RKG  P TPE+G W L+L N   
Sbjct: 383 NTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQL-NGGQ 441

Query: 424 LKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 483
             A+  P  S     +L +V + LD E G +SFY  + M H+YTF   F E+++P F  C
Sbjct: 442 YWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTFRVNFQERVFPLFSVC 501


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  201 bits (512), Expect = 1e-51
 Identities = 149/467 (31%), Positives = 232/467 (49%), Gaps = 29/467 (6%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLD 97
           E+ CP+C D F +P+ + CGH+FC+ CI    +     + CP C+      N   N  L 
Sbjct: 13  EVTCPICLDPFVEPVSIECGHSFCQECISQVGK--GGGSVCPVCRQRFLLKNLRPNRQLA 70

Query: 98  KLVEKIKKLPLLKGH----PQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFLQI 153
            +V  +K++           +C  HGE L LF + DGK +C+ C  +R    +    + +
Sbjct: 71  NMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCWVCAQSRKH--RDHAMVPL 128

Query: 154 SDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQF 213
            +A   + E+L +  G+L    +  + L        A  K+     +  +  EF++   F
Sbjct: 129 EEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVETQKSRIHAEFVQQKNF 188

Query: 214 LHSKEKDILTEL----REEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDF 269
           L  +E+  L EL    RE+ + L E+ E  L+Q Q Q L     L+S   +    ++ + 
Sbjct: 189 LVEEEQRQLQELEKDEREQLRILGEK-EAKLAQ-QSQAL---QELISELDRRCHSSALEL 243

Query: 270 LKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDP 329
           L+++  +L   E     L   ++ S +L    +   ++ M+        C     +TLDP
Sbjct: 244 LQEVIIVLERSESWN--LKDLDITSPELRSVCHVPGLKKML------RTCA--VHITLDP 293

Query: 330 KTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTK 389
            TA+P L+LS+ +  V  GD ++ +P + ERFDS   VLG++ F SGK YWEV+V  K  
Sbjct: 294 DTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEA 353

Query: 390 WTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDY 449
           W +GV R+S+ RKG   L+ + GFW + L N+   +A   P   L L     +VGI+LDY
Sbjct: 354 WDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVGIFLDY 413

Query: 450 EGGQLSFYNAKTM-THIYTFSN-TFMEKLYPYFCPCLNDGGENKEPL 494
           E G +SFYN     + IY+FS   F   L P+F P  NDGG+N  PL
Sbjct: 414 EAGMVSFYNITDHGSLIYSFSECAFTGPLRPFFSPGFNDGGKNTAPL 460


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  199 bits (507), Expect = 4e-51
 Identities = 137/467 (29%), Positives = 225/467 (48%), Gaps = 26/467 (5%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETF-CPECKMLCQYNNCTFNPVL 96
           E  C +C D+  DP+ + CGHNFC +CIQ  W L  +E F CP C+  CQ  +   N  L
Sbjct: 13  EAKCSICLDYLSDPVTIECGHNFCRSCIQQSW-LDLQELFPCPVCRHQCQEGHFRSNTQL 71

Query: 97  DKLVEKIKKLPLLKGHPQ-------CPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKE 149
            +++E  K L   K + +       C +H + L +F K D  ++C  C       G    
Sbjct: 72  GRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDHQGHHVR 131

Query: 150 FLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLK 209
            ++ + A+H+     +  Q  L+  L +LQ L + Q +     +E   + +Q +S EF  
Sbjct: 132 PIEKA-AIHYRKRFCSYIQ-PLKKQLADLQKLISTQSKKPLELREMVENQRQELSSEFEH 189

Query: 210 LHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDF 269
           L+QFL  +++ +L+ L EE K   +++  N++         K  L  +  +  + +  + 
Sbjct: 190 LNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKV-VELSELSELEL 248

Query: 270 LKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDP 329
           L  I     S  +     ++  + S  L       P QY     +Q  +      + LDP
Sbjct: 249 LSQIKIFYESENE-----SSPSIFSIHLKRDGCSFPPQYSA---LQRIIKKFKVEIILDP 300

Query: 330 KTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTK 389
           +TAHPNL++S+ +  V     K+ +P  P+RF     VLG   F SG+ +WE+EV  K++
Sbjct: 301 ETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSE 360

Query: 390 WTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGIYLDY 449
           W +G+ ++S+  K   P + +Q  W + L++         P+  L L      +GI+LDY
Sbjct: 361 WAIGICKDSLPTKARRPSSAQQECWRIELQDDGYHAPGAFPT-PLLLEVKARAIGIFLDY 419

Query: 450 EGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHI 496
           E G++SFYN    +HI TF++TF   L PYF       G + +PL I
Sbjct: 420 EMGEISFYNMAEKSHICTFTDTFTGPLRPYFYV-----GPDSQPLRI 461


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  199 bits (505), Expect = 6e-51
 Identities = 140/469 (29%), Positives = 216/469 (46%), Gaps = 29/469 (6%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLD 97
           E  C +C D+F DP+M  CGHNFC  CI+  W        CPEC+ L    N   N  L 
Sbjct: 13  EATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQRNLRPNRPLA 72

Query: 98  KLVEKIKKLPLLKGHPQ--CPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISD 155
           K+ E  ++L      PQ  CP H E L  F   + +L+C  C+  R     +     + D
Sbjct: 73  KMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAACE--RSGEHWAHRVRPLQD 130

Query: 156 AVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLH 215
           A      +L      L   +++    +    E     ++     +Q+V  EF +L + L 
Sbjct: 131 AAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQNVLGEFERLRRLLA 190

Query: 216 SKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKDITT 275
            +E+ +L  L EE   +   +    + L +Q     +++  ++ +  Q  +   L+DI  
Sbjct: 191 EEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELEGRC-QLPALGLLQDIKD 249

Query: 276 LLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPKTAHPN 335
            L  + Q +K+     +      + +  G ++         TL      +TLDP TA+P 
Sbjct: 250 ALRRV-QDVKLQPPEVVPMELRTVCRVPGLVE---------TLRRFRGDVTLDPDTANPE 299

Query: 336 LVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVV 395
           L+LS+ + SV  GD+++ +PD PERFD    VLG   FTSG+ YWEVEV  +T W +GV 
Sbjct: 300 LILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVC 359

Query: 396 RESIIRKGSCPLTPEQGFWLLRLRN---QTDLKALDLPSFSLTLTNNLDKVGIYLDYEGG 452
           RE++ RK    L+   GFW+L        +  +AL        L +   +VGI+LDYE G
Sbjct: 360 RENVNRKEKGELSAGNGFWILVFLGSYYNSSERAL------APLRDPPRRVGIFLDYEAG 413

Query: 453 QLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPLHILHPQ 500
            LSFY+A   + ++ F    F   L P F P       +  P+ I  P+
Sbjct: 414 HLSFYSATDGSLLFIFPEIPFSGTLRPLFSPL----SSSPTPMTICRPK 458


>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  193 bits (491), Expect = 3e-49
 Identities = 144/456 (31%), Positives = 222/456 (48%), Gaps = 31/456 (6%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAK-----ETFC-PECKMLCQYNNCT 91
           E  C +C     +P+ ++CGH++C  CI DF++  ++     ETFC P+C+     ++  
Sbjct: 13  EATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSLR 72

Query: 92  FNPVLDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFL 151
            N  L  L+E +K+         C EHGE   LF + +G+LIC++C+ A    G +   +
Sbjct: 73  PNKQLGSLIEALKETDQ---EMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHTTALV 129

Query: 152 QISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAH----KENKLHLQQHVSMEF 207
           +  D    + E+L     +  T LK+L+     QK + A      KE     +Q +  +F
Sbjct: 130 E--DVCQGYKEKLQ----KAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183

Query: 208 LKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCL-LAKDMLVSIQAKTEQQNS 266
             L  FLH +EK  L  L +E     E+  L+  +  E  L L  + L S   + E++  
Sbjct: 184 KNLQCFLHEEEKSYLWRLEKE-----EQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQ 238

Query: 267 FDFLKDITTLLHSLEQGMKV-LATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPL 325
               K +  +  +L +   V L T E +S +L+       + + V + ++         +
Sbjct: 239 GSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVS----V 294

Query: 326 TLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVA 385
           TLDP TAH  L+LS+ +  V  G  ++       RF +   VLG  GFTSG+ Y+EV+V 
Sbjct: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVG 354

Query: 386 KKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGI 445
           + T W +GV  E++ R       P+ GFW LRL  +    AL  P  SL L      VGI
Sbjct: 355 EGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGI 414

Query: 446 YLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYF 480
           +LDYE G +SFYN  T  HI+TF   +F + L PYF
Sbjct: 415 FLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  190 bits (482), Expect = 3e-48
 Identities = 141/466 (30%), Positives = 226/466 (48%), Gaps = 47/466 (10%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWR----LQAKETFCPECKMLCQYNNCTFN 93
           +  CP+C D+ ++P+ + CGH+FC  CI +F       Q     CP+C+   + +    N
Sbjct: 13  DARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSGFRPN 72

Query: 94  PVLDKLVEKIKKLPLLKGHP--QCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFL 151
             L  LVE +++L L  G    +C  HGE+L  F + D   +C+ C        ++    
Sbjct: 73  RQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVCDAG--PEHRTHRTA 130

Query: 152 QISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHK----ENKLHLQ-QHVSME 206
            + +A   +  +L   Q  LE   KEL+    + +EA    K    + K+ +Q Q   +E
Sbjct: 131 PLQEAAGSYQVKL---QMALELMRKELEDA--LTQEANVGKKTVIWKEKVEMQRQRFRLE 185

Query: 207 FLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNS 266
           F K   FL  +E+  L  L  E +A  + +  + S+L +Q    K++   +Q + ++   
Sbjct: 186 FEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQERCQRP-- 243

Query: 267 FDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLC-PGLSPL 325
                     L  LE    VL+  + ++R   L     P+      E++   C PG   L
Sbjct: 244 ---------ALGLLEGVRGVLSRSKAVTR---LEAENIPM------ELKTACCIPGRREL 285

Query: 326 T--------LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGK 377
                    LDP TAHP+L+L+    SV  G+  + +P++PERFD+   +LG + F+SG+
Sbjct: 286 LRKFQVDVKLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGR 345

Query: 378 WYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLT 437
            YWEV V +  +W +GV ++++ RKG    +PE G W L L    +   L  PS  L   
Sbjct: 346 HYWEVLVGEGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQL 405

Query: 438 NNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPC 483
            +   +GI+LDYE G++SFYN    ++IYTF+  F   L PYF  C
Sbjct: 406 ESPRCIGIFLDYEAGEISFYNVTDGSYIYTFNQLFSGLLRPYFFIC 451


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  185 bits (469), Expect = 1e-46
 Identities = 141/477 (29%), Positives = 228/477 (47%), Gaps = 31/477 (6%)

Query: 26  LPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQA----KETFCPEC 81
           + S   +  +  E++CP+C    R+P+ + CGHNFC AC+  +  +      +   CP C
Sbjct: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLC 60

Query: 82  KMLCQYNNCTFNPVLDKLVEKIKKLPL-----LKGHPQCPEHGENLKLFSKPDGKLICFQ 136
           K   +  +   N  L  +VE I++L L     L     C EHGE +  F + D   +C  
Sbjct: 61  KEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLCVV 120

Query: 137 CKDARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENK 196
           C++A      +  FL+  DA   + E++      L    +E+Q +++ + + +       
Sbjct: 121 CREAGEHATHTMRFLE--DAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178

Query: 197 LHLQQHVSMEFLKLHQFLHSKEKDILTELR-EEGKALNEEMELNLSQLQEQCLLAKDMLV 255
              +Q V  EF  L +FL  ++  +L +L  ++G  L +  E +L    E C  +  ++ 
Sbjct: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSA-LIE 237

Query: 256 SIQAKTEQQNSFDFLKDITTLLHSLEQ---GMKVLATRELISRKLNLGQYKGPIQYMVWR 312
            ++ K E+  + + L DI + L   E       V  + EL  R  +  Q   P+Q    R
Sbjct: 238 ELEEKNERP-ARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQ----R 292

Query: 313 EMQ---DTLCPGL----SPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSV 365
           EM+   + LC  L    + ++LDP+T+HP L+LS+           +  PD+P+RFD + 
Sbjct: 293 EMKMFLEKLCFELDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRAT 352

Query: 366 AVLGSRGFTSGK--WYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTD 423
            VL   G T G+  W   +++A     TVGVV E + RKG   L PE+G W +RL     
Sbjct: 353 CVLAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLA-WGF 411

Query: 424 LKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF 480
           + AL      LTL     +V + LDYE G ++F NA T   IYTF+ +F  K+ P+F
Sbjct: 412 VSALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTFTASFTRKVIPFF 468


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  184 bits (466), Expect = 2e-46
 Identities = 149/488 (30%), Positives = 237/488 (48%), Gaps = 52/488 (10%)

Query: 31  VIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRL----QAKETFCPECKMLCQ 86
           V+ DI  E+ CP+C +   +PL + CGH+FC+ACI    R     Q  E  CP C+   Q
Sbjct: 5   VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 64

Query: 87  YNNCTFNPVLDKLVEKIKKLPLLKGHPQ----CPEHGENLKLFSKPDGKLICFQCKDARL 142
             N   N  L  +V +++++ L  G       C +HGE L+LF + DGK+IC+ C+ ++ 
Sbjct: 65  PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 124

Query: 143 SVGQSKEFLQISDAVHFFTEELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQ 201
             G             F  EE+A + Q + + +LK+L+      ++  A  +E K   + 
Sbjct: 125 HRGHHT----------FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKN 174

Query: 202 H-------VSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDML 254
                   +  EF +L   L   E+  L +L +E K     +E   + L  Q    ++++
Sbjct: 175 QMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELI 234

Query: 255 VSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPI---QYMVW 311
             ++ +  Q ++ + L+D++ +    E     L   E +  KL    ++ P       V 
Sbjct: 235 SDLERRC-QGSTMELLQDVSDVTERSE--FWTLRKPEALPTKLR-SMFRAPDLKRMLRVC 290

Query: 312 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPER-FDSSVAVLGS 370
           RE+ D     +  +TL+P TA+ NLVL+K++  V     K   P   E+ +D SV  LGS
Sbjct: 291 RELTDVQSYWVD-VTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSV--LGS 347

Query: 371 RGFTSGKWYWEVEVAKKTKWTVGVVRESI-----------IRKGSCPLTPEQGFWLLRLR 419
           + F+SGK YWEV+VAKKT W +GV   S+                    P+ G+W++ L+
Sbjct: 348 QHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQ 407

Query: 420 NQTDLKALD--LPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTH-IYTFSN-TFMEK 475
           +  + +A +   PS  L++T    +VG++LDYE G +SFYN       IYTFS   F   
Sbjct: 408 HNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTT 467

Query: 476 LYPYFCPC 483
           L PYF PC
Sbjct: 468 LCPYFNPC 475


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  184 bits (466), Expect = 2e-46
 Identities = 149/488 (30%), Positives = 237/488 (48%), Gaps = 52/488 (10%)

Query: 31  VIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRL----QAKETFCPECKMLCQ 86
           V+ DI  E+ CP+C +   +PL + CGH+FC+ACI    R     Q  E  CP C+   Q
Sbjct: 33  VLVDIREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQ 92

Query: 87  YNNCTFNPVLDKLVEKIKKLPLLKGHPQ----CPEHGENLKLFSKPDGKLICFQCKDARL 142
             N   N  L  +V +++++ L  G       C +HGE L+LF + DGK+IC+ C+ ++ 
Sbjct: 93  PGNLRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQE 152

Query: 143 SVGQSKEFLQISDAVHFFTEELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQ 201
             G             F  EE+A + Q + + +LK+L+      ++  A  +E K   + 
Sbjct: 153 HRGHHT----------FLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKN 202

Query: 202 H-------VSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDML 254
                   +  EF +L   L   E+  L +L +E K     +E   + L  Q    ++++
Sbjct: 203 QMEPERCRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELI 262

Query: 255 VSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPI---QYMVW 311
             ++ +  Q ++ + L+D++ +    E     L   E +  KL    ++ P       V 
Sbjct: 263 SDLERRC-QGSTMELLQDVSDVTERSE--FWTLRKPEALPTKLR-SMFRAPDLKRMLRVC 318

Query: 312 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPER-FDSSVAVLGS 370
           RE+ D     +  +TL+P TA+ NLVL+K++  V     K   P   E+ +D SV  LGS
Sbjct: 319 RELTDVQSYWVD-VTLNPHTANLNLVLAKNRRQVRFVGAKVSGPSCLEKHYDCSV--LGS 375

Query: 371 RGFTSGKWYWEVEVAKKTKWTVGVVRESI-----------IRKGSCPLTPEQGFWLLRLR 419
           + F+SGK YWEV+VAKKT W +GV   S+                    P+ G+W++ L+
Sbjct: 376 QHFSSGKHYWEVDVAKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQ 435

Query: 420 NQTDLKALD--LPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTH-IYTFSN-TFMEK 475
           +  + +A +   PS  L++T    +VG++LDYE G +SFYN       IYTFS   F   
Sbjct: 436 HNHEYRAYEDSSPSLLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTT 495

Query: 476 LYPYFCPC 483
           L PYF PC
Sbjct: 496 LCPYFNPC 503


>gi|56605981 tripartite motif-containing 72 [Homo sapiens]
          Length = 477

 Score =  181 bits (460), Expect = 1e-45
 Identities = 139/478 (29%), Positives = 223/478 (46%), Gaps = 30/478 (6%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKE--TFCPECKMLCQYNNCTFNPV 95
           EL CPLC   F  P+   CGH+FC AC+       A +    CP C+   +    + N  
Sbjct: 11  ELSCPLCLQLFDAPVTAECGHSFCRACLGRVAGEPAADGTVLCPCCQAPTRPQALSTNLQ 70

Query: 96  LDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFLQISD 155
           L +LVE + ++P  +GH  C EH + L ++ + D  L+C  C  A L   +    L  ++
Sbjct: 71  LARLVEGLAQVP--QGH--CEEHLDPLSIYCEQDRALVCGVC--ASLGSHRGHRLLPAAE 124

Query: 156 AVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLHQFLH 215
           A      +L  Q+ QL+      +    + +  +   +E     +  V  +  K+  FL 
Sbjct: 125 AHARLKTQLPQQKLQLQEACMRKEKSVAVLEHQLVEVEETVRQFRGAVGEQLGKMRVFLA 184

Query: 216 SKEKDILTELR----EEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLK 271
           + E  +  E      E G AL  E+  +L+   EQ    + +L  +  K + +    FL 
Sbjct: 185 ALEGSLDCEAERVRGEAGVALRRELG-SLNSYLEQLRQMEKVLEEVADKPQTE----FLM 239

Query: 272 DITTLLHSLEQGMKVLATRELISR-KLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDPK 330
               +   L+   K+LA     +R  + L       ++ VWR+M   L P L  LT DP 
Sbjct: 240 KYCLVTSRLQ---KILAESPPPARLDIQLPIISDDFKFQVWRKMFRALMPALEELTFDPS 296

Query: 331 TAHPNLVLSKSQTSVWHGDIKKIMP--DDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKT 388
           +AHP+LV+S S   V   + +K  P  +DP +FD +VAV+  +  + G+ YWEV+V  K 
Sbjct: 297 SAHPSLVVSSSGRRVECSE-QKAPPAGEDPRQFDKAVAVVAHQQLSEGEHYWEVDVGDKP 355

Query: 389 KWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKA---LDLPSFSLTLTNNLDKVGI 445
           +W +GV+     R+G     P QG WLL LR    L+A      P    +      ++G+
Sbjct: 356 RWALGVIAAEAPRRGRLHAVPSQGLWLLGLREGKILEAHVEAKEPRALRSPERRPTRIGL 415

Query: 446 YLDYEGGQLSFYNAK---TMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEPLHILHPQ 500
           YL +  G LSFY+A     +  ++ F       +YP+F  C +D G+N +PL ++ P+
Sbjct: 416 YLSFGDGVLSFYDASDADALVPLFAFHERLPRPVYPFFDVCWHDKGKNAQPLLLVGPE 473


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  174 bits (441), Expect = 2e-43
 Identities = 135/482 (28%), Positives = 230/482 (47%), Gaps = 49/482 (10%)

Query: 42  PLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLDKLVE 101
           P C+    DP+  +C  + C          QA  +  P C   CQ ++   +P       
Sbjct: 313 PRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPR-CQDSHERKSP------G 365

Query: 102 KIKKLPLLKGHPQCPEHGENLKL-FSKPDGKLICFQCKDARLSVGQSKEFLQISDAVHFF 160
            +   PL    PQC  H + ++L F +   + IC  C     S+ Q  +  ++       
Sbjct: 366 SLSPQPL----PQCKRHLKQVQLLFCEDHDEPICLIC-----SLSQEHQGHRVRPI---- 412

Query: 161 TEELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENKLH-------LQQHVSMEFLKLHQ 212
            EE+A++ + +++  L+ L+ LR   +E  +  +E  +        L+Q V  +  +++ 
Sbjct: 413 -EEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYY 471

Query: 213 FLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLKD 272
           FL  +E   +  L + G+ + +  +   +++ +   L   ++  ++AK E Q+ ++ L+D
Sbjct: 472 FLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAK-ECQSEWELLQD 530

Query: 273 ITTLLHSLEQGM--KVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLT---- 326
           I  +LH  +     +   T + I +K+ L   K        +   +TL   +        
Sbjct: 531 IGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPEL 590

Query: 327 -----------LDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTS 375
                      LD +TA+PNL+ S    SV  G+  + +PD P+RFDS + VLGS  F S
Sbjct: 591 IGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLS 650

Query: 376 GKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLT 435
           G+ YWEVEV  KT W +G  + SI RKG+  L+PE G+W++ +  + + +A  +P   L 
Sbjct: 651 GRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLL 710

Query: 436 LTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFCPCLNDGGENKEPL 494
           +     +VGI++DY  G +SFYN    +HIYTF++ +F   L P F P   DGG+N  PL
Sbjct: 711 IKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPL 770

Query: 495 HI 496
            I
Sbjct: 771 TI 772


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  174 bits (441), Expect = 2e-43
 Identities = 128/469 (27%), Positives = 219/469 (46%), Gaps = 49/469 (10%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFW--------RLQAKETF-CPECKMLCQYN 88
           E  C +C D+F DP+M +CGHNFC ACIQ  W        R + K +F CPEC+ +    
Sbjct: 13  EATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQR 72

Query: 89  NCTFNPVLDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSK 148
           N   N +L K+ E  ++ P L+    C EH E LKLF + D   IC  C+++R    +  
Sbjct: 73  NLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR--EHRLH 130

Query: 149 EFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFL 208
             L   +AV  +  +L      L   +     L+  +++++A  +      ++ + +EF 
Sbjct: 131 RVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFE 190

Query: 209 KLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 268
           K++ +L  +E+ +L  L  E +     +  +++ L  Q    + +L+ ++ ++  Q    
Sbjct: 191 KMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERS-TQGPLQ 249

Query: 269 FLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPG------- 321
            L+D+                +E +SRK N+   + P      R       PG       
Sbjct: 250 MLQDM----------------KEPLSRKNNV-SVQCPEVAPPTRPRTVCRVPGQIEVLRG 292

Query: 322 -LSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPD-----DPERFDSSVAVLGSRGFTS 375
            L  +  D  +A+P L+L +S+   + G      P+       +RF +    +G   F+S
Sbjct: 293 FLEDVVPDATSAYPYLLLYESRQRRYLGS----SPEGSGFCSKDRFVAYPCAVGQTAFSS 348

Query: 376 GKWYWEV--EVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFS 433
           G+ YWEV   +     W +GV R+++ RK   P  PE GFW+++L   T   +       
Sbjct: 349 GRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTP 408

Query: 434 LTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFC 481
           + L      +GI+LD+E G++SFY+    +H++T+S  TF   L P+FC
Sbjct: 409 VMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFC 457


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  174 bits (441), Expect = 2e-43
 Identities = 128/469 (27%), Positives = 219/469 (46%), Gaps = 49/469 (10%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFW--------RLQAKETF-CPECKMLCQYN 88
           E  C +C D+F DP+M +CGHNFC ACIQ  W        R + K +F CPEC+ +    
Sbjct: 13  EATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQR 72

Query: 89  NCTFNPVLDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSK 148
           N   N +L K+ E  ++ P L+    C EH E LKLF + D   IC  C+++R    +  
Sbjct: 73  NLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESR--EHRLH 130

Query: 149 EFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFL 208
             L   +AV  +  +L      L   +     L+  +++++A  +      ++ + +EF 
Sbjct: 131 RVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFE 190

Query: 209 KLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 268
           K++ +L  +E+ +L  L  E +     +  +++ L  Q    + +L+ ++ ++  Q    
Sbjct: 191 KMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERS-TQGPLQ 249

Query: 269 FLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYMVWREMQDTLCPG------- 321
            L+D+                +E +SRK N+   + P      R       PG       
Sbjct: 250 MLQDM----------------KEPLSRKNNV-SVQCPEVAPPTRPRTVCRVPGQIEVLRG 292

Query: 322 -LSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPD-----DPERFDSSVAVLGSRGFTS 375
            L  +  D  +A+P L+L +S+   + G      P+       +RF +    +G   F+S
Sbjct: 293 FLEDVVPDATSAYPYLLLYESRQRRYLGS----SPEGSGFCSKDRFVAYPCAVGQTAFSS 348

Query: 376 GKWYWEV--EVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFS 433
           G+ YWEV   +     W +GV R+++ RK   P  PE GFW+++L   T   +       
Sbjct: 349 GRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTP 408

Query: 434 LTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYFC 481
           + L      +GI+LD+E G++SFY+    +H++T+S  TF   L P+FC
Sbjct: 409 VMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFFC 457


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  172 bits (436), Expect = 6e-43
 Identities = 129/470 (27%), Positives = 208/470 (44%), Gaps = 38/470 (8%)

Query: 33  QDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTF 92
           +DI  EL CP+C D+F+DP+ + CGHNFC  C+   W        CPEC+          
Sbjct: 4   EDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAALRP 63

Query: 93  NPVLDKLVEKIKKLPLLKGHP-QCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFL 151
           N  L +L EK ++  L    P  C  H E L+LF + D + +C  C++++    Q+    
Sbjct: 64  NWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQ--EHQTHAMA 121

Query: 152 QISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLHLQQHVSMEFLKLH 211
            I +A   + E+L   Q  L   +K++  L++++ +     K+     +  +S EF KLH
Sbjct: 122 PIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLH 181

Query: 212 QFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFDFLK 271
            FL  +E   L  L +E +   +++  N  +L +     K +++ +  K++         
Sbjct: 182 NFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQ--------- 232

Query: 272 DITTLLHSLEQGMKVLATREL--ISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPLTLDP 329
                L  L+   +VL   E+  ++  L   + K   Q  + +EM       ++   L  
Sbjct: 233 --APTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVN---LAE 287

Query: 330 KTAHPNLVLSKSQ---------------TSVWHGDIKKIMPDDP---ERFDSSVAVLGSR 371
            TAHP LV S+                 +S W+       P      ERF     VLG  
Sbjct: 288 DTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKN 347

Query: 372 GFTSGKWYWEVEVAKKTKWTVGVVRESIIR-KGSCPLTPEQGFWLLRLRNQTDLKALDLP 430
            FTSGK YWEVE     +  VGV RE ++       ++P+ G W +          +  P
Sbjct: 348 VFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAIYWSAAGYWPLIGFP 407

Query: 431 SFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF 480
                    L +VG+YLD   G +SFY+A    H++TFS + + +L P+F
Sbjct: 408 GTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVSRLRPFF 457


>gi|63054855 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  171 bits (434), Expect = 1e-42
 Identities = 98/245 (40%), Positives = 139/245 (56%), Gaps = 10/245 (4%)

Query: 254 LVSIQAKTEQQNSFDFLKDITTLL--HSLEQGMKVLATRELISRKLNLGQYKGPIQYMVW 311
           L+  Q + +++  ++ + ++  LL  H+ E+G    A ++L S      + K       W
Sbjct: 175 LIWKQRRAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSEL----KLKRAAANSGW 230

Query: 312 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR 371
           R  +         +TLDP TAHP L+LS+ Q  V  GD ++ +PD+P+RFD  V++LGS 
Sbjct: 231 RRARLHFVA----VTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSE 286

Query: 372 GFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPS 431
            FT+G  YWEV V  KTKW +GV  ES+ RKG    +P  G WLLR     + +AL  P 
Sbjct: 287 YFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQ 346

Query: 432 FSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENK 491
            S  L      VGI+LDYE G +SFYN    +HI+TF++ F   L P+F PCL+DGG+N 
Sbjct: 347 TSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNT 406

Query: 492 EPLHI 496
            PL I
Sbjct: 407 APLVI 411


>gi|19923536 erythroblast membrane-associated protein precursor
           [Homo sapiens]
          Length = 475

 Score =  171 bits (434), Expect = 1e-42
 Identities = 98/245 (40%), Positives = 139/245 (56%), Gaps = 10/245 (4%)

Query: 254 LVSIQAKTEQQNSFDFLKDITTLL--HSLEQGMKVLATRELISRKLNLGQYKGPIQYMVW 311
           L+  Q + +++  ++ + ++  LL  H+ E+G    A ++L S      + K       W
Sbjct: 175 LIWKQRRAKEKLLYEHVTEVDNLLSDHAKEKGKLHKAVKKLRSEL----KLKRAAANSGW 230

Query: 312 REMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR 371
           R  +         +TLDP TAHP L+LS+ Q  V  GD ++ +PD+P+RFD  V++LGS 
Sbjct: 231 RRARLHFVA----VTLDPDTAHPKLILSEDQRCVRLGDRRQPVPDNPQRFDFVVSILGSE 286

Query: 372 GFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPS 431
            FT+G  YWEV V  KTKW +GV  ES+ RKG    +P  G WLLR     + +AL  P 
Sbjct: 287 YFTTGCHYWEVYVGDKTKWILGVCSESVSRKGKVTASPANGHWLLRQSRGNEYEALTSPQ 346

Query: 432 FSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENK 491
            S  L      VGI+LDYE G +SFYN    +HI+TF++ F   L P+F PCL+DGG+N 
Sbjct: 347 TSFRLKEPPRCVGIFLDYEAGVISFYNVTNKSHIFTFTHNFSGPLRPFFEPCLHDGGKNT 406

Query: 492 EPLHI 496
            PL I
Sbjct: 407 APLVI 411


>gi|94536782 tripartite motif-containing 35 isoform 2 [Homo sapiens]
          Length = 493

 Score =  166 bits (421), Expect = 3e-41
 Identities = 142/483 (29%), Positives = 215/483 (44%), Gaps = 44/483 (9%)

Query: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECKMLCQYNNCTFNPVLD 97
           EL C +C D FRD + L CGHNFC  C+   W +Q   T CP CK      +   N  L+
Sbjct: 18  ELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPT-CPVCKDRASPADLRTNHTLN 76

Query: 98  KLVEKI-------KKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCK-DARLSVGQSKE 149
            LVEK+        +    +    C  H   L LF   D +L+C  C+ D R    Q   
Sbjct: 77  NLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPR---HQGHR 133

Query: 150 FLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKE-NKLHLQQHVSMEFL 208
              + D  H F  +    +  L    K    +R    EAIA H +     L+  +  EF 
Sbjct: 134 VQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRR-SYEAIAKHNQVEAAWLEGRIRQEFD 192

Query: 209 KLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQAKTEQQNSFD 268
           KL +FL  +E+ IL  + EE +      +  + QL E+  +    +  +Q + ++     
Sbjct: 193 KLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKED---- 248

Query: 269 FLKDITTLLHSLEQGMKVLATRE----LISRKLNLGQYKGPIQYMVWREMQDTLCPGLSP 324
              D++ L+    +  ++  T E         +++ +Y G +QY VW++M  ++     P
Sbjct: 249 ---DVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASV--ESVP 303

Query: 325 LTLDPKTAHPNLVLSKSQTSVW-HGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVE 383
            + DP TA   L +S   TSV  HG   ++  ++PERF S+  +LGSR F+ G   WEV 
Sbjct: 304 FSFDPNTAAGWLSVSDDLTSVTNHG--YRVQVENPERFSSAPCLLGSRVFSQGSHAWEVA 361

Query: 384 VAKKTKWTVGVVRESIIRKG--------SCPLTPEQGFWLLRLRN--QTDLKALDLPSFS 433
           +     W VGVVR   +R+         SC      GFW +      + D      P+ S
Sbjct: 362 LGGLQSWRVGVVR---VRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATS 418

Query: 434 LTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYFCPCLNDGGENKEP 493
             +     ++ + L+ E G+LSFY+A+   H+YTF   F E + PYF      G    EP
Sbjct: 419 PLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGE-VRPYFYLGGARGAGPPEP 477

Query: 494 LHI 496
           L I
Sbjct: 478 LRI 480


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  161 bits (407), Expect = 1e-39
 Identities = 133/471 (28%), Positives = 220/471 (46%), Gaps = 40/471 (8%)

Query: 27  PSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKET----FCPECK 82
           PS  V+ ++     C LC     D + + CGH FC  C+    ++ A+ +     CP   
Sbjct: 5   PSLKVVHELPA---CTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSSGKILLCP--- 58

Query: 83  MLCQYNNCTFNPVLDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARL 142
            LCQ       P+       +   PL  G   C EHGE +  F + D + +C  C++   
Sbjct: 59  -LCQEEEQAETPMAP-----VPLGPL--GETYCEEHGEKIYFFCENDAEFLCVFCREGPT 110

Query: 143 SVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLR---NMQKEAIAAHKENKLHL 199
               +  FL   +A+  + + L  +   L T   E++ ++   + + + +    E+K H 
Sbjct: 111 HQAHTVGFLD--EAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKH- 167

Query: 200 QQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLLAKDMLVSIQA 259
              V   F +L Q L  +   +L  LRE  + + +E +  ++++ E+       +  ++ 
Sbjct: 168 --QVETAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEE 225

Query: 260 KTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKL--NLGQYKGPIQYM--VWREMQ 315
           K +Q  S + L+D+       E  MK   + E IS  L   +  +   I  +  + R   
Sbjct: 226 KCQQPAS-ELLQDVRVNQSRCE--MKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFS 282

Query: 316 DTLCPGLS----PLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSR 371
           + L   L      +TLDP+TA  +LVLS+ + SV +   KK +PD P RFD   AVLG  
Sbjct: 283 ENLAHHLEIDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFP 342

Query: 372 GFTSGKWYWEV--EVAKKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDL 429
           GF+SG+  W+V  ++      TVGV  E + RKG   L+ E G W + + +Q    A   
Sbjct: 343 GFSSGRHRWQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQ-QCWASTS 401

Query: 430 PSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTMTHIYTFSNTFMEKLYPYF 480
           P   L L+     V + LDYE GQ++ +NA+T   I+TF+ +F  K++P+F
Sbjct: 402 PGTDLPLSEIPRGVRVALDYEAGQVTLHNAQTQEPIFTFTASFSGKVFPFF 452


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  158 bits (399), Expect = 1e-38
 Identities = 136/496 (27%), Positives = 240/496 (48%), Gaps = 61/496 (12%)

Query: 26  LPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACI----QDFWRLQAKETFCPEC 81
           + SK+++ ++  E+ CP+C +   +PL L CGH+ C ACI    ++       ++ CP C
Sbjct: 1   MASKILL-NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVC 59

Query: 82  KMLCQYNNCTFNPVLDKLVEKIKKLPLL----KGHPQCPEHGENLKLFSKPDGKLICFQC 137
            +   + +   N  L  +VE++K++ L     K    C  HGE L LF K D K+IC+ C
Sbjct: 60  GISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLC 119

Query: 138 KDARLSVGQSKEFLQISDAVHFFTEELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENK 196
           + ++   G               TEE+  + Q +L+  LK L+      ++  A  +E K
Sbjct: 120 ERSQEHRGHHT----------VLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEK 169

Query: 197 LHLQ-------QHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLL 249
              +       Q +  EF +L   L+++E+  L  L EE K   ++      +L +Q  L
Sbjct: 170 TSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQL 229

Query: 250 AKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYM 309
            ++++  ++ ++ Q ++ + L+D++ ++   E  +  L   +++S+KL    +   +  M
Sbjct: 230 VRELISDVECRS-QWSTMELLQDMSGIMKWSE--IWRLKKPKMVSKKLKTVFHAPDLSRM 286

Query: 310 V--WREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAV 367
           +  +RE+    C  +  +TL+    + NLVLS+ Q  V    I             +  V
Sbjct: 287 LQMFRELTAVRCYWVD-VTLNSVNLNLNLVLSEDQRQVISVPIWPFQC-------YNYGV 338

Query: 368 LGSRGFTSGKWYWEVEVAKKTKWTVG------------VVRESIIRKG-SCPLTPEQGFW 414
           LGS+ F+SGK YWEV+V+KKT W +G            VVR    R+       P  G+W
Sbjct: 339 LGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYW 398

Query: 415 LLRLRNQ------TDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTM-THIYT 467
           ++ L+N+       +  + D    +L++     +VG++LDYE G +SF+N  +  + IY 
Sbjct: 399 VIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYK 458

Query: 468 FSN-TFMEKLYPYFCP 482
           FS   F + +YPYF P
Sbjct: 459 FSKCCFSQPVYPYFNP 474


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  158 bits (399), Expect = 1e-38
 Identities = 136/496 (27%), Positives = 240/496 (48%), Gaps = 61/496 (12%)

Query: 26  LPSKVVIQDITMELHCPLCNDWFRDPLMLSCGHNFCEACI----QDFWRLQAKETFCPEC 81
           + SK+++ ++  E+ CP+C +   +PL L CGH+ C ACI    ++       ++ CP C
Sbjct: 1   MASKILL-NVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVC 59

Query: 82  KMLCQYNNCTFNPVLDKLVEKIKKLPLL----KGHPQCPEHGENLKLFSKPDGKLICFQC 137
            +   + +   N  L  +VE++K++ L     K    C  HGE L LF K D K+IC+ C
Sbjct: 60  GISYSFEHLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLC 119

Query: 138 KDARLSVGQSKEFLQISDAVHFFTEELAIQ-QGQLETTLKELQTLRNMQKEAIAAHKENK 196
           + ++   G               TEE+  + Q +L+  LK L+      ++  A  +E K
Sbjct: 120 ERSQEHRGHHT----------VLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEK 169

Query: 197 LHLQ-------QHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCLL 249
              +       Q +  EF +L   L+++E+  L  L EE K   ++      +L +Q  L
Sbjct: 170 TSWKYQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQL 229

Query: 250 AKDMLVSIQAKTEQQNSFDFLKDITTLLHSLEQGMKVLATRELISRKLNLGQYKGPIQYM 309
            ++++  ++ ++ Q ++ + L+D++ ++   E  +  L   +++S+KL    +   +  M
Sbjct: 230 VRELISDVECRS-QWSTMELLQDMSGIMKWSE--IWRLKKPKMVSKKLKTVFHAPDLSRM 286

Query: 310 V--WREMQDTLCPGLSPLTLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAV 367
           +  +RE+    C  +  +TL+    + NLVLS+ Q  V    I             +  V
Sbjct: 287 LQMFRELTAVRCYWVD-VTLNSVNLNLNLVLSEDQRQVISVPIWPFQC-------YNYGV 338

Query: 368 LGSRGFTSGKWYWEVEVAKKTKWTVG------------VVRESIIRKG-SCPLTPEQGFW 414
           LGS+ F+SGK YWEV+V+KKT W +G            VVR    R+       P  G+W
Sbjct: 339 LGSQYFSSGKHYWEVDVSKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYW 398

Query: 415 LLRLRNQ------TDLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFYNAKTM-THIYT 467
           ++ L+N+       +  + D    +L++     +VG++LDYE G +SF+N  +  + IY 
Sbjct: 399 VIGLQNKCKYGVFEESLSSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYK 458

Query: 468 FSN-TFMEKLYPYFCP 482
           FS   F + +YPYF P
Sbjct: 459 FSKCCFSQPVYPYFNP 474


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.415 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,786,674
Number of Sequences: 37866
Number of extensions: 899468
Number of successful extensions: 3958
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 240
Number of HSP's successfully gapped in prelim test: 255
Number of HSP's that attempted gapping in prelim test: 3120
Number of HSP's gapped (non-prelim): 758
length of query: 500
length of database: 18,247,518
effective HSP length: 106
effective length of query: 394
effective length of database: 14,233,722
effective search space: 5608086468
effective search space used: 5608086468
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.