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Search of human proteins with 88943074
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|88943074 PREDICTED: similar to Phosphodiesterase 4D
interacting protein [Homo sapiens]
(134 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|88943074 PREDICTED: similar to Phosphodiesterase 4D interacti... 267 2e-72
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 248 8e-67
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 248 8e-67
gi|50658077 phosphodiesterase 4D interacting protein isoform 4 [... 248 8e-67
gi|50658075 phosphodiesterase 4D interacting protein isoform 3 [... 248 8e-67
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform... 69 9e-13
gi|58535451 CDK5 regulatory subunit associated protein 2 isoform... 69 9e-13
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 45 2e-05
gi|119120918 coiled-coil domain containing 64 [Homo sapiens] 42 1e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 41 3e-04
gi|110815815 centlein isoform 1 [Homo sapiens] 41 3e-04
gi|167555106 centlein isoform 2 [Homo sapiens] 41 3e-04
gi|148746195 trichohyalin [Homo sapiens] 41 3e-04
gi|119120861 formin-like 3 isoform 2 [Homo sapiens] 41 3e-04
gi|119120874 formin-like 3 isoform 1 [Homo sapiens] 41 3e-04
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 40 4e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 40 4e-04
gi|153945715 myosin VC [Homo sapiens] 40 6e-04
gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens] 40 7e-04
gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens] 40 7e-04
gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens] 40 7e-04
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 39 0.001
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 39 0.001
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 39 0.001
gi|55770834 centromere protein F [Homo sapiens] 39 0.001
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 39 0.001
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 39 0.001
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 38 0.002
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 38 0.002
gi|196115290 glial fibrillary acidic protein isoform 2 [Homo sap... 38 0.003
>gi|88943074 PREDICTED: similar to Phosphodiesterase 4D interacting
protein [Homo sapiens]
Length = 134
Score = 267 bits (683), Expect = 2e-72
Identities = 134/134 (100%), Positives = 134/134 (100%)
Query: 1 MGYEMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETE 60
MGYEMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETE
Sbjct: 1 MGYEMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETE 60
Query: 61 HVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQV 120
HVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQV
Sbjct: 61 HVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQV 120
Query: 121 KPDQYTEALAQRDK 134
KPDQYTEALAQRDK
Sbjct: 121 KPDQYTEALAQRDK 134
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 248 bits (634), Expect = 8e-67
Identities = 125/127 (98%), Positives = 126/127 (99%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+N ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE
Sbjct: 47 RNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 106
Query: 68 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 127
NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE
Sbjct: 107 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 166
Query: 128 ALAQRDK 134
ALAQRDK
Sbjct: 167 ALAQRDK 173
Score = 37.7 bits (86), Expect = 0.003
Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 16/98 (16%)
Query: 9 NTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 68
N EL+ ++ L+ ELQ+K Q L + W EAE + ++Q +H+ L +
Sbjct: 397 NQELRKALQQLQEELQNKSQQL-RAW----------EAEKYNEIRTQEQNIQHLNHSLSH 445
Query: 69 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 106
K QLLQE L + L E N L EKL+
Sbjct: 446 KEQLLQEFRELLQYRDNSDKTL-----EANEMLLEKLR 478
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 248 bits (634), Expect = 8e-67
Identities = 125/127 (98%), Positives = 126/127 (99%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+N ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE
Sbjct: 47 RNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 106
Query: 68 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 127
NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE
Sbjct: 107 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 166
Query: 128 ALAQRDK 134
ALAQRDK
Sbjct: 167 ALAQRDK 173
Score = 37.7 bits (86), Expect = 0.003
Identities = 31/98 (31%), Positives = 45/98 (45%), Gaps = 16/98 (16%)
Query: 9 NTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 68
N EL+ ++ L+ ELQ+K Q L + W EAE + ++Q +H+ L +
Sbjct: 397 NQELRKALQQLQEELQNKSQQL-RAW----------EAEKYNEIRTQEQNIQHLNHSLSH 445
Query: 69 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 106
K QLLQE L + L E N L EKL+
Sbjct: 446 KEQLLQEFRELLQYRDNSDKTL-----EANEMLLEKLR 478
Score = 36.2 bits (82), Expect = 0.008
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 15 EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQ 74
E ESL+ L + HL + E EL Q ERQQ E + E + + +
Sbjct: 1928 ETESLREALLSSRSHLQEL-----------EKELEHQKVERQQLLEDLREKQQEVLHFRE 1976
Query: 75 EESRLAKNEAARMAALVEAEKEC--NLELSEKLKGVTKNWEDVPGDQVK 121
E L +N++ LV +++C +L E L+ + +E + G+ K
Sbjct: 1977 ERLSLQENDSRLQHKLVLLQQQCEEKQQLFESLQSELQIYEALYGNSKK 2025
>gi|50658077 phosphodiesterase 4D interacting protein isoform 4
[Homo sapiens]
Length = 173
Score = 248 bits (634), Expect = 8e-67
Identities = 125/127 (98%), Positives = 126/127 (99%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+N ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE
Sbjct: 47 RNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 106
Query: 68 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 127
NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE
Sbjct: 107 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 166
Query: 128 ALAQRDK 134
ALAQRDK
Sbjct: 167 ALAQRDK 173
>gi|50658075 phosphodiesterase 4D interacting protein isoform 3
[Homo sapiens]
Length = 310
Score = 248 bits (634), Expect = 8e-67
Identities = 125/127 (98%), Positives = 126/127 (99%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+N ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE
Sbjct: 184 RNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 243
Query: 68 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 127
NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE
Sbjct: 244 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 303
Query: 128 ALAQRDK 134
ALAQRDK
Sbjct: 304 ALAQRDK 310
>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
[Homo sapiens]
Length = 1814
Score = 69.3 bits (168), Expect = 9e-13
Identities = 42/105 (40%), Positives = 62/105 (59%)
Query: 9 NTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 68
N ELKVEVESLKRELQ+++Q L K VE+L +E++R E+ +++ + V +LL
Sbjct: 103 NIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTK 162
Query: 69 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
+I LL+++ A+ E + A E EK L L KL + K E
Sbjct: 163 RILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHE 207
Score = 31.6 bits (70), Expect = 0.20
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 15/107 (14%)
Query: 11 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQN--------EAELRRQFEERQQETEHV 62
ELK+ ++S + +Q K+ + EN++S E R+ E Q E +
Sbjct: 225 ELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKE 284
Query: 63 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 109
E +IQ L+E+ R + E A EK+ +L+ + ++G+T
Sbjct: 285 RNSFEERIQALEEDLREKEREIA-------TEKKNSLKRDKAIQGLT 324
Score = 26.9 bits (58), Expect = 4.9
Identities = 17/65 (26%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 11 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKI 70
+L+ EVE L+ E+ ++++ ++ + ++L S++ +L Q +Q +H+ E K
Sbjct: 438 DLRNEVEKLRNEVNEREKAMENRY---KSLLSESNKKLHNQ----EQVIKHLTESTNQKD 490
Query: 71 QLLQE 75
LLQ+
Sbjct: 491 VLLQK 495
>gi|58535451 CDK5 regulatory subunit associated protein 2 isoform a
[Homo sapiens]
Length = 1893
Score = 69.3 bits (168), Expect = 9e-13
Identities = 42/105 (40%), Positives = 62/105 (59%)
Query: 9 NTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 68
N ELKVEVESLKRELQ+++Q L K VE+L +E++R E+ +++ + V +LL
Sbjct: 103 NIELKVEVESLKRELQEREQLLIKASKAVESLAEAGGSEIQRVKEDARKKVQQVEDLLTK 162
Query: 69 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
+I LL+++ A+ E + A E EK L L KL + K E
Sbjct: 163 RILLLEKDVTAAQAELEKAFAGTETEKALRLRLESKLSEMKKMHE 207
Score = 31.6 bits (70), Expect = 0.20
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 15/107 (14%)
Query: 11 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQN--------EAELRRQFEERQQETEHV 62
ELK+ ++S + +Q K+ + EN++S E R+ E Q E +
Sbjct: 225 ELKLSLKSKEALIQCLKEEKSQMACPDENVSSGELRGLCAAPREEKERETEAAQMEHQKE 284
Query: 63 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 109
E +IQ L+E+ R + E A EK+ +L+ + ++G+T
Sbjct: 285 RNSFEERIQALEEDLREKEREIA-------TEKKNSLKRDKAIQGLT 324
Score = 26.9 bits (58), Expect = 4.9
Identities = 17/65 (26%), Positives = 37/65 (56%), Gaps = 7/65 (10%)
Query: 11 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKI 70
+L+ EVE L+ E+ ++++ ++ + ++L S++ +L Q +Q +H+ E K
Sbjct: 438 DLRNEVEKLRNEVNEREKAMENRY---KSLLSESNKKLHNQ----EQVIKHLTESTNQKD 490
Query: 71 QLLQE 75
LLQ+
Sbjct: 491 VLLQK 495
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 44.7 bits (104), Expect = 2e-05
Identities = 34/125 (27%), Positives = 62/125 (49%), Gaps = 8/125 (6%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+N L ESLK L+ + +K ++E+L S AE +++E+ +E + YE+L
Sbjct: 1561 ENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSKIAE-STEWQEKHKELQKEYEIL- 1618
Query: 68 NKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTE 127
LQ ++ NEA R+ +VEA ++ EL KL+ N ++ + +Q E
Sbjct: 1619 -----LQSYENVS-NEAERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEME 1672
Query: 128 ALAQR 132
+ ++
Sbjct: 1673 EMKEK 1677
Score = 37.4 bits (85), Expect = 0.004
Identities = 25/97 (25%), Positives = 50/97 (51%), Gaps = 3/97 (3%)
Query: 9 NTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 68
+TE ++E+E +K +LQ+K++ + A + ++ A+ + EE + + E E
Sbjct: 139 STEEEMEIEKIKHKLQEKEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQE-KEE 197
Query: 69 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 105
I LQ ++L++ +A + A V EK+ E +L
Sbjct: 198 FISTLQ--AQLSQTQAEQAAQQVVREKDARFETQVRL 232
Score = 35.4 bits (80), Expect = 0.014
Identities = 26/118 (22%), Positives = 57/118 (48%), Gaps = 1/118 (0%)
Query: 3 YEMPSQNTELKVEVES-LKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEH 61
YE + + E+ S L E+ K+Q + + E AELR+Q ++ +E E+
Sbjct: 2356 YEQLETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQVAIAELRQQHDKEIKELEN 2415
Query: 62 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQ 119
+ E + +L+EE++ A ++ ++ ++ K+ N++ +L K+ + D+
Sbjct: 2416 LLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDR 2473
Score = 32.3 bits (72), Expect = 0.12
Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 24/122 (19%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
Q L+V+++ K EL++K L++ + E N +LRR F Q+E + + + +E
Sbjct: 2551 QKQLLEVQLQQNK-ELENKYAKLEEKLKESEEANE----DLRRSFNALQEEKQDLSKEIE 2605
Query: 68 N----------KIQLLQEESRLA---------KNEAARMAALVEAEKECNLELSEKLKGV 108
+ ++ LQEE L + E R++AL + ++ EL E+L V
Sbjct: 2606 SLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCV 2665
Query: 109 TK 110
K
Sbjct: 2666 QK 2667
Score = 29.3 bits (64), Expect = 0.99
Identities = 25/138 (18%), Positives = 55/138 (39%), Gaps = 14/138 (10%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVY 63
+M + E K+ +L+ E+ + ++ L S+ A ++ E +++T H+
Sbjct: 323 KMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHIL 382
Query: 64 ELL--------------ENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVT 109
L + +LLQ+++ A A + L + ++ + E+S+ L +
Sbjct: 383 SLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLP 442
Query: 110 KNWEDVPGDQVKPDQYTE 127
+ PD Y E
Sbjct: 443 LQQHETASQTSFPDVYNE 460
Score = 29.3 bits (64), Expect = 0.99
Identities = 30/142 (21%), Positives = 65/142 (45%), Gaps = 22/142 (15%)
Query: 5 MPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRR------QFEERQ-- 56
+ Q ++ + +E LK + + +H + W +Q E +L++ Q E ++
Sbjct: 2236 LKDQLRQMSIHMEELKINIS-RLEHDKQIWES----KAQTEVQLQQKVCDTLQGENKELL 2290
Query: 57 ---QETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
+ET H+Y +N++ L+ E + K++ ++ +E K E L+G+ + E
Sbjct: 2291 SQLEETRHLYHSSQNELAKLESELKSLKDQLTDLSNSLEKCK----EQKGNLEGIIRQQE 2346
Query: 114 -DVPGDQVKPDQY-TEALAQRD 133
D+ + +Q T+ A R+
Sbjct: 2347 ADIQNSKFSYEQLETDLQASRE 2368
Score = 28.9 bits (63), Expect = 1.3
Identities = 27/128 (21%), Positives = 56/128 (43%), Gaps = 20/128 (15%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVY 63
E P+Q++ E +K++LQ+K++ + A + SQ +AE Q
Sbjct: 173 EQPAQSSTEMEEFVMMKQQLQEKEEFISTLQAQL----SQTQAEQAAQ------------ 216
Query: 64 ELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPD 123
+++ K + + RL ++E ++ + E E+ +KL+ + + E+ V
Sbjct: 217 QVVREKDARFETQVRLHEDELLQLVTQADVE----TEMQQKLRVLQRKLEEHEESLVGRA 272
Query: 124 QYTEALAQ 131
Q + L Q
Sbjct: 273 QVVDLLQQ 280
Score = 28.9 bits (63), Expect = 1.3
Identities = 27/117 (23%), Positives = 53/117 (45%), Gaps = 25/117 (21%)
Query: 8 QNTELKVEVESLKR---ELQDKKQHLDKTWADVENL-----------------NSQNEAE 47
+N L+ E+++LK+ EL+++KQ L K VE+ N + E
Sbjct: 1950 KNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKE 2009
Query: 48 LRRQFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEK 104
L+ +E+QQE + + K + +E A + V+ E + +LE++++
Sbjct: 2010 LQELLKEKQQEVKQL-----QKDCIRYQEKISALERTVKALEFVQTESQKDLEITKE 2061
Score = 28.5 bits (62), Expect = 1.7
Identities = 26/128 (20%), Positives = 52/128 (40%), Gaps = 11/128 (8%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQ-----NEAELRRQFEERQQE 58
E N +L+ +L+ E QD + ++ + L Q E L + + +
Sbjct: 2578 ESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQLKVK 2637
Query: 59 TEHVYELL------ENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNW 112
E V+ L + +I L+EE + EAA+ +E + + L+ G+ +N
Sbjct: 2638 EEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAGIMRNE 2697
Query: 113 EDVPGDQV 120
+ ++V
Sbjct: 2698 TETAEERV 2705
Score = 26.2 bits (56), Expect = 8.4
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 17/81 (20%)
Query: 7 SQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQ----NEA-----ELRRQFEERQQ 57
+Q + EV+SLK+ + + D+ +++NL Q N+ L+ Q +E Q
Sbjct: 2867 AQPSTSPAEVQSLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQD 2926
Query: 58 ETEHVYELLENKIQLLQEESR 78
+T+ Q++QEE R
Sbjct: 2927 KTK--------AFQIMQEELR 2939
>gi|119120918 coiled-coil domain containing 64 [Homo sapiens]
Length = 573
Score = 42.0 bits (97), Expect = 1e-04
Identities = 24/76 (31%), Positives = 41/76 (53%), Gaps = 11/76 (14%)
Query: 1 MGYEMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETE 60
+G + +N ++ + E + +EL DK +HL+ Q + ELRR+FE R+ E E
Sbjct: 116 LGKALLERNQDMSRQYEQMHKELTDKLEHLE-----------QEKHELRRRFENREGEWE 164
Query: 61 HVYELLENKIQLLQEE 76
LE+ ++ LQ+E
Sbjct: 165 GRVSELESDVKQLQDE 180
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 41.2 bits (95), Expect = 3e-04
Identities = 28/103 (27%), Positives = 53/103 (51%), Gaps = 6/103 (5%)
Query: 12 LKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQ 71
L+ ++ S K + Q L+K ++E + E L + Q T+ Y+LLE+K++
Sbjct: 907 LREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDE-----QSTDDRYKLLESKLE 961
Query: 72 -LLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
L++ + + + A + A +E N +L ++LK V KN+E
Sbjct: 962 STLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYE 1004
Score = 26.2 bits (56), Expect = 8.4
Identities = 24/99 (24%), Positives = 48/99 (48%), Gaps = 12/99 (12%)
Query: 8 QNTELKVE-VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQ---------Q 57
++ E+K E + +L+ L++ + + +++ + EA +RQ EER +
Sbjct: 966 KSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGE 1025
Query: 58 ETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 96
+ + E E +LL+ + RL E R A ++AEK+
Sbjct: 1026 DNKWERESQETTRELLKVKDRLI--EVERNNATLQAEKQ 1062
>gi|110815815 centlein isoform 1 [Homo sapiens]
Length = 1406
Score = 41.2 bits (95), Expect = 3e-04
Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 7/103 (6%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+N L+ E L+++ +DK Q + T V+N QN ++ EE ++ + +LL
Sbjct: 200 ENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLN 259
Query: 68 NKIQLLQEESRLAKNEAARMAA-------LVEAEKECNLELSE 103
+ +L ++E+ L K + + A L+EA KE + S+
Sbjct: 260 DLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSK 302
>gi|167555106 centlein isoform 2 [Homo sapiens]
Length = 391
Score = 41.2 bits (95), Expect = 3e-04
Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 7/103 (6%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+N L+ E L+++ +DK Q + T V+N QN ++ EE ++ + +LL
Sbjct: 200 ENAFLRKEFSDLEKKFKDKSQEIKDTKECVQNKEEQNRLVIKNLEEENKKLSTRCTDLLN 259
Query: 68 NKIQLLQEESRLAKNEAARMAA-------LVEAEKECNLELSE 103
+ +L ++E+ L K + + A L+EA KE + S+
Sbjct: 260 DLEKLRKQEAHLRKEKYSTDAKIKTFEDNLIEARKEVEVSQSK 302
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.8 bits (94), Expect = 3e-04
Identities = 29/86 (33%), Positives = 47/86 (54%), Gaps = 7/86 (8%)
Query: 8 QNTELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELRRQFEERQ-QETEHVY- 63
+ EL+ E E L RE ++K+ Q L++ + + E + + E LR + E+R+ QE E Y
Sbjct: 1112 EEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYR 1171
Query: 64 ---ELLENKIQLLQEESRLAKNEAAR 86
EL + + QLL+EE + E R
Sbjct: 1172 EEEELQQEEEQLLREEQEKRRQERER 1197
Score = 38.5 bits (88), Expect = 0.002
Identities = 31/124 (25%), Positives = 56/124 (45%), Gaps = 13/124 (10%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKT--------WADVEN-----LNSQNEAELRR 50
E + LK E E+ + E + +KQ L + W +E + E +LRR
Sbjct: 450 EQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRR 509
Query: 51 QFEERQQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTK 110
+ EER+++ E E Q L+ E +L + + R L++ E+E LE + + + +
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Query: 111 NWED 114
E+
Sbjct: 570 EQEE 573
Score = 37.4 bits (85), Expect = 0.004
Identities = 33/128 (25%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Query: 8 QNTELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL 65
+ E++ E E L RE +K+ Q L++ + + E L + E LR + E+R+QE E Y
Sbjct: 1142 EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201
Query: 66 LENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQY 125
E + +++ +++ + + E EKE N K+ K E+ Q++ Q
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSDLKWQWEPEKE-NAVRDNKV--YCKGRENEQFRQLEDSQL 1258
Query: 126 TEALAQRD 133
+ +Q+D
Sbjct: 1259 RDRQSQQD 1266
Score = 35.8 bits (81), Expect = 0.011
Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 15/97 (15%)
Query: 11 ELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELRRQFE-ERQQETEHVY---- 63
EL+ E E L RE ++K+ Q ++ + + E L + E L + E R+QE E Y
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 64 ELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE 100
EL + + QLL+EE + + E E++C E
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQ--------ERERQCREE 1113
Score = 35.4 bits (80), Expect = 0.014
Identities = 23/84 (27%), Positives = 44/84 (52%), Gaps = 2/84 (2%)
Query: 4 EMPSQNTEL-KVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHV 62
E+ + +L K+E + L+RE Q+++Q + + + L + E E R Q EER+++ E
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE-QQLRRKQEEERREQQEERREQQERR 328
Query: 63 YELLENKIQLLQEESRLAKNEAAR 86
+ E + Q L+ E + + R
Sbjct: 329 EQQEERREQQLRREQEERREQQLR 352
Score = 33.9 bits (76), Expect = 0.040
Identities = 31/103 (30%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 11 ELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELRRQFEERQ-QETEHVY---- 63
EL+ E E L RE +K+ Q ++ + E L + E LR + E+R+ QE E Y
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 64 ELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 106
E+ + + QLL+EE K + E+E E + L+
Sbjct: 1145 EVQQEEEQLLREEPE--KRRRQELERQYREEEELQQEEEQLLR 1185
Score = 33.5 bits (75), Expect = 0.052
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Query: 8 QNTELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELR-----RQFEERQQETE 60
+ EL+ E E L RE ++K+ Q ++ + + L + E LR R+ +ER+++
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR 1051
Query: 61 HVYELLENKIQLLQEESRLAKNE 83
EL + + QLL EE + +
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQ 1074
Score = 33.5 bits (75), Expect = 0.052
Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 9/106 (8%)
Query: 8 QNTELKVEVESLKRELQD--KKQHLDKTWADVENLNSQNEAELR-----RQFEERQQETE 60
+ EL+ E E L E ++ ++Q L++ + E L + E LR R+ +ER+++
Sbjct: 1052 EEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCR 1111
Query: 61 HVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLK 106
EL + + QLL+EE K + E+E E + L+
Sbjct: 1112 EEEELQQEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLR 1155
Score = 33.1 bits (74), Expect = 0.069
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 11/100 (11%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQET-------- 59
Q + + E + + +LQ K H + + D E L + ELRR+ E +Q+
Sbjct: 178 QEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV 237
Query: 60 ---EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 96
E E + + L +EE +L + E R L E E++
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277
Score = 33.1 bits (74), Expect = 0.069
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 10/112 (8%)
Query: 12 LKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELR-----RQFEERQQETEHVYE 64
L+ E E L+RE ++K+ Q ++ + + E L + E LR R+ +ER+++ +
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 65 LLENKIQLLQEESRLAKNEAARMAALVEAE---KECNLELSEKLKGVTKNWE 113
L + + QLL EE + + E E +E L E+ K + WE
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWE 1017
Score = 31.6 bits (70), Expect = 0.20
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 1/63 (1%)
Query: 17 ESLKRELQ-DKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQE 75
+ L+RE Q ++Q L + + E +LRR+ EE + E +H E E +++ QE
Sbjct: 393 QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQE 452
Query: 76 ESR 78
E R
Sbjct: 453 ERR 455
Score = 31.6 bits (70), Expect = 0.20
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 7/76 (9%)
Query: 8 QNTELKVEVESLKRELQDKK--QHLDKTWADVENLNSQNEAELRRQFEERQ-QETEHVY- 63
++ +L+ + E L E +K+ Q +K + + E L + E LR + E+R+ QE E Y
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYR 1021
Query: 64 ---ELLENKIQLLQEE 76
EL + + QLL+EE
Sbjct: 1022 KKDELQQEEEQLLREE 1037
Score = 31.2 bits (69), Expect = 0.26
Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 3/95 (3%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEE--RQQETEH 61
E P + EL+ E E L R+L+ ++ ++ + + + E +LRR+ EE R+Q+ E
Sbjct: 263 EEPQRQRELQEEEEQL-RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 62 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKE 96
+ + Q + E +L + + R + E+E
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQE 356
Score = 31.2 bits (69), Expect = 0.26
Identities = 28/134 (20%), Positives = 58/134 (43%), Gaps = 13/134 (9%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEE--------- 54
E Q E + + LKRE ++++ L + + + + +L+R EE
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 55 RQQETEHVYELLENKIQLLQEESR----LAKNEAARMAALVEAEKECNLELSEKLKGVTK 110
++E E E +++ QEE R + E R+ + +E++ E E+ + + K
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 111 NWEDVPGDQVKPDQ 124
E+ +Q + +Q
Sbjct: 552 REEEKRLEQERREQ 565
Score = 30.4 bits (67), Expect = 0.44
Identities = 21/79 (26%), Positives = 39/79 (49%), Gaps = 12/79 (15%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+ +L+ E +RELQ++++ L K ELRR+ +E +Q+ + + E
Sbjct: 256 EEEKLQEEEPQRQRELQEEEEQLRKL----------ERQELRRERQEEEQQQQRLRR--E 303
Query: 68 NKIQLLQEESRLAKNEAAR 86
+++ QEE R + E R
Sbjct: 304 QQLRRKQEEERREQQEERR 322
Score = 29.3 bits (64), Expect = 0.99
Identities = 23/92 (25%), Positives = 44/92 (47%), Gaps = 4/92 (4%)
Query: 17 ESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQ-QETEHVYELLENKIQLLQE 75
+ L+RE +++++ L K + + E L+R+ EER+ Q + E + +++ QE
Sbjct: 536 QQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQE 595
Query: 76 ---ESRLAKNEAARMAALVEAEKECNLELSEK 104
E RL + E R+ E+ E E+
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Score = 29.3 bits (64), Expect = 0.99
Identities = 27/104 (25%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 15 EVESLKRELQDKKQHLDKTWADVEN----LNSQNEAELRRQ-FEERQQETEHVYELLENK 69
EVE L++E + ++Q L + + E L S+ + E R+Q QQE E +
Sbjct: 606 EVERLEQE-ERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Query: 70 IQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
+ L++ + E R L E E+E + E++K W+
Sbjct: 665 EERLEQRLKREHEEERREQELAEEEQE---QARERIKSRIPKWQ 705
Score = 28.9 bits (63), Expect = 1.3
Identities = 27/137 (19%), Positives = 61/137 (44%), Gaps = 10/137 (7%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVY 63
E + +L E + E + ++Q L + + + + E E R+Q +R+QE
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600
Query: 64 ELLENKIQLLQEESRLAKN------EAARMAALVEAEKECNLELSEKLKGVTKNWEDVPG 117
L +++ L++E R + E R L+++E+ + + + + + ++
Sbjct: 601 RLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE----QEERRQQQLRREQQERRE 656
Query: 118 DQVKPDQYTEALAQRDK 134
++K ++ E L QR K
Sbjct: 657 QRLKREEEEERLEQRLK 673
Score = 28.5 bits (62), Expect = 1.7
Identities = 20/71 (28%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 11 ELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQE---TEHVYELLE 67
+L+ + E +RE Q++++ + E + E +LRR+ EER+++ E E E
Sbjct: 305 QLRRKQEEERREQQEERREQQER---REQQEERREQQLRREQEERREQQLRREQEEERRE 361
Query: 68 NKIQLLQEESR 78
+++ QEE R
Sbjct: 362 QQLRREQEEER 372
Score = 28.1 bits (61), Expect = 2.2
Identities = 32/128 (25%), Positives = 56/128 (43%), Gaps = 19/128 (14%)
Query: 17 ESLKREL-----------QDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETE-HVYE 64
+ L+RE Q++++H K + + E E RR + +R++ETE H E
Sbjct: 411 QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQE 470
Query: 65 LLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQ 124
+ +++ QEE R R L E E+ E E + + + E+ ++K +
Sbjct: 471 RRKQQLKRDQEEER-----RERWLKLEEEERREQQERRE--QQLRREQEERREQRLKRQE 523
Query: 125 YTEALAQR 132
E L QR
Sbjct: 524 EEERLQQR 531
Score = 27.7 bits (60), Expect = 2.9
Identities = 22/74 (29%), Positives = 37/74 (50%), Gaps = 2/74 (2%)
Query: 15 EVESLKRELQDKKQHLD-KTWADVENLNSQNEAELRRQFEERQ-QETEHVYELLENKIQL 72
E E L+RE Q + + D K+ + + L + E + RRQ +R+ +E E + + E +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 73 LQEESRLAKNEAAR 86
QE R + E R
Sbjct: 1355 RQERDRKFREEELR 1368
Score = 27.3 bits (59), Expect = 3.8
Identities = 28/136 (20%), Positives = 60/136 (44%), Gaps = 10/136 (7%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHL-----DKTWADVENLNSQNEAELRRQFEERQQE 58
E P + + E+ L+R+ +++KQ D+ + + E + + R+ EE+ QE
Sbjct: 203 EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQE 262
Query: 59 TEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGD 118
E + + +L +EE +L K E + + E++ L + + K E+
Sbjct: 263 EEP-----QRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Query: 119 QVKPDQYTEALAQRDK 134
Q + + E Q+++
Sbjct: 318 QEERREQQERREQQEE 333
>gi|119120861 formin-like 3 isoform 2 [Homo sapiens]
Length = 976
Score = 40.8 bits (94), Expect = 3e-04
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 6/79 (7%)
Query: 22 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 81
EL++ HL + D+EN N AEL +Q +R++E E + E EN + RL K
Sbjct: 349 ELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIK 408
Query: 82 NEAARMAALVEAEKECNLE 100
+ ++ C+LE
Sbjct: 409 EKEEAF------QRRCHLE 421
>gi|119120874 formin-like 3 isoform 1 [Homo sapiens]
Length = 1027
Score = 40.8 bits (94), Expect = 3e-04
Identities = 24/79 (30%), Positives = 38/79 (48%), Gaps = 6/79 (7%)
Query: 22 ELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEESRLAK 81
EL++ HL + D+EN N AEL +Q +R++E E + E EN + RL K
Sbjct: 400 ELEEHVSHLTEKLLDLENENMMRVAELEKQLLQREKELESIKETYENTSHQVHTLRRLIK 459
Query: 82 NEAARMAALVEAEKECNLE 100
+ ++ C+LE
Sbjct: 460 EKEEAF------QRRCHLE 472
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 40.4 bits (93), Expect = 4e-04
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 27/137 (19%)
Query: 6 PSQNTELKVEVESLKRELQDKKQHLDKTWADVEN------LNSQNEAELRRQFEERQQET 59
PS+ +L+ E L++EL+ + L A+VEN LN + E LR Q E +++
Sbjct: 156 PSKVEQLQDETNHLRKELESVGRQLQ---AEVENNQMLSLLNRRQEERLREQEERLREQE 212
Query: 60 EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPG-- 117
E ++E E +L ++E RL + E E+ C EKL G + E+V
Sbjct: 213 ERLHEQEE---RLCEQEERLCEQE----------ERLCE---QEKLPGQERLLEEVEKLL 256
Query: 118 DQVKPDQYTEALAQRDK 134
+Q + + E L +R++
Sbjct: 257 EQERRQEEQERLLERER 273
Score = 28.9 bits (63), Expect = 1.3
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 24 QDKKQHLDKTWADVENLNSQNEA-ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN 82
Q+K ++ +VE L Q E + + ER++ + V ELLE + +L Q++ RL +
Sbjct: 239 QEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQ 297
Query: 83 EAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 134
E R E E+ LE +L WE + + +P E L +K
Sbjct: 298 ETLR-----ELERLRELERMLEL-----GWEALYEQRAEPRSGFEELNNENK 339
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 40.4 bits (93), Expect = 4e-04
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 13/118 (11%)
Query: 9 NTELKVEVESLKRELQDKKQHLDKTWADVEN-----------LNSQNEAE--LRRQFEER 55
NT+L++ L ++L+ +K+ + T D++ L Q E + L++ FE
Sbjct: 760 NTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDFETL 819
Query: 56 QQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
QET+ +E L N+IQ E + K E + + K+ ++S+ LK +E
Sbjct: 820 SQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFE 877
Score = 37.0 bits (84), Expect = 0.005
Identities = 26/117 (22%), Positives = 58/117 (49%), Gaps = 11/117 (9%)
Query: 7 SQNTELKVEVESLKRELQDKKQHLDKTWADVENLN----------SQNEAELRRQFEERQ 56
+Q +L+ +++ + LQDK+Q L+K ++ + SQ E+ L ++++E+
Sbjct: 660 AQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHL-KEYKEKY 718
Query: 57 QETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
E E LE +I+ L+ +S K + ++ +++ N +L + ++K E
Sbjct: 719 LSLEQKTEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLE 775
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 40.0 bits (92), Expect = 6e-04
Identities = 27/95 (28%), Positives = 54/95 (56%), Gaps = 8/95 (8%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVY 63
++ N+EL+ + E ++ +LQ+K + L + ++NL Q +++++ E ++ E +
Sbjct: 960 KLQKHNSELETQKEQIQLKLQEKTEELKEK---MDNLTKQLFDDVQKE-ERQRMLLEKSF 1015
Query: 64 EL----LENKIQLLQEESRLAKNEAARMAALVEAE 94
EL E +IQ L+EE + K+E ++ LVE E
Sbjct: 1016 ELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGE 1050
Score = 28.5 bits (62), Expect = 1.7
Identities = 24/126 (19%), Positives = 54/126 (42%), Gaps = 10/126 (7%)
Query: 12 LKVEVESLKRELQDKKQHLDKTWADVENLNSQNE---------AELRRQFEERQQETEHV 62
L E+ L++ +++ + +V L S+N +EL +Q ++ +
Sbjct: 1176 LSQEINHLQKLFREENDINESIRHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQ 1235
Query: 63 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKP 122
E ++ K++ L + ++ E +EA+ E + + EKL + ++ D +K
Sbjct: 1236 AEKMKGKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEA-SDHLKK 1294
Query: 123 DQYTEA 128
TE+
Sbjct: 1295 QFETES 1300
>gi|110347418 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 39.7 bits (91), Expect = 7e-04
Identities = 29/137 (21%), Positives = 59/137 (43%), Gaps = 5/137 (3%)
Query: 3 YEMPSQNTELKVE-VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEH 61
Y Q E+K E + L+ +LQ H + D + E + +E Q++ E
Sbjct: 712 YRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEE 771
Query: 62 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECN----LELSEKLKGVTKNWEDVPG 117
YE+LENK++ + E +A + + + + + E ++++ +T E++
Sbjct: 772 KYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKR 831
Query: 118 DQVKPDQYTEALAQRDK 134
+ Q EA+ + K
Sbjct: 832 EHTSYKQQLEAVNEAIK 848
Score = 30.8 bits (68), Expect = 0.34
Identities = 20/100 (20%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 12 LKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQ 71
+ +E+E LKRE KQ L+ +++ SQ E + + + ++ E + + +
Sbjct: 822 ITLELEELKREHTSYKQQLEAVNEAIKSYESQIEV-MAAEVAKNKESVNKAQEEVTKQKE 880
Query: 72 LLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKN 111
++ + + K + A +A E + L++ E ++K+
Sbjct: 881 VITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKH 920
>gi|110347425 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 39.7 bits (91), Expect = 7e-04
Identities = 29/137 (21%), Positives = 59/137 (43%), Gaps = 5/137 (3%)
Query: 3 YEMPSQNTELKVE-VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEH 61
Y Q E+K E + L+ +LQ H + D + E + +E Q++ E
Sbjct: 712 YRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEE 771
Query: 62 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECN----LELSEKLKGVTKNWEDVPG 117
YE+LENK++ + E +A + + + + + E ++++ +T E++
Sbjct: 772 KYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKR 831
Query: 118 DQVKPDQYTEALAQRDK 134
+ Q EA+ + K
Sbjct: 832 EHTSYKQQLEAVNEAIK 848
Score = 30.8 bits (68), Expect = 0.34
Identities = 20/100 (20%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 12 LKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQ 71
+ +E+E LKRE KQ L+ +++ SQ E + + + ++ E + + +
Sbjct: 822 ITLELEELKREHTSYKQQLEAVNEAIKSYESQIEV-MAAEVAKNKESVNKAQEEVTKQKE 880
Query: 72 LLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKN 111
++ + + K + A +A E + L++ E ++K+
Sbjct: 881 VITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKH 920
>gi|110347420 structural maintenance of chromosomes 2 [Homo sapiens]
Length = 1197
Score = 39.7 bits (91), Expect = 7e-04
Identities = 29/137 (21%), Positives = 59/137 (43%), Gaps = 5/137 (3%)
Query: 3 YEMPSQNTELKVE-VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEH 61
Y Q E+K E + L+ +LQ H + D + E + +E Q++ E
Sbjct: 712 YRQLKQQWEMKTEEADLLQTKLQQSSYHKQQEELDALKKTIEESEETLKNTKEIQRKAEE 771
Query: 62 VYELLENKIQLLQEESRLAKNEAARMAALVEAEKECN----LELSEKLKGVTKNWEDVPG 117
YE+LENK++ + E +A + + + + + E ++++ +T E++
Sbjct: 772 KYEVLENKMKNAEAERERELKDAQKKLDCAKTKADASSKKMKEKQQEVEAITLELEELKR 831
Query: 118 DQVKPDQYTEALAQRDK 134
+ Q EA+ + K
Sbjct: 832 EHTSYKQQLEAVNEAIK 848
Score = 30.8 bits (68), Expect = 0.34
Identities = 20/100 (20%), Positives = 47/100 (47%), Gaps = 1/100 (1%)
Query: 12 LKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQ 71
+ +E+E LKRE KQ L+ +++ SQ E + + + ++ E + + +
Sbjct: 822 ITLELEELKREHTSYKQQLEAVNEAIKSYESQIEV-MAAEVAKNKESVNKAQEEVTKQKE 880
Query: 72 LLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKN 111
++ + + K + A +A E + L++ E ++K+
Sbjct: 881 VITAQDTVIKAKYAEVAKHKEQNNDSQLKIKELDHNISKH 920
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 39.3 bits (90), Expect = 0.001
Identities = 36/139 (25%), Positives = 68/139 (48%), Gaps = 14/139 (10%)
Query: 6 PSQNTELKVEVESLKRELQDKKQHLDKTWADVEN------LNSQNEAELRRQFEERQQET 59
PS+ +L+ E L++EL+ + L A+VEN LN + E LR Q E +++
Sbjct: 156 PSKVEQLQDETNHLRKELESVGRQLQ---AEVENNQMLSLLNRRQEERLREQEERLREQE 212
Query: 60 EHVYE----LLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDV 115
E + E L E + +L ++E RL + E R+ E +E L E+ + + + E +
Sbjct: 213 ERLREQEERLCEQEERLREQEERLREQE-ERLCEQEERLREHEERLCEQEERLCEQEERL 271
Query: 116 PGDQVKPDQYTEALAQRDK 134
+ + + E L ++++
Sbjct: 272 REQEERLHEQEERLCEQEE 290
Score = 29.3 bits (64), Expect = 0.99
Identities = 32/112 (28%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 24 QDKKQHLDKTWADVENLNSQNEA-ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN 82
Q+K ++ +VE L Q E + + ER++ E V ELLE + +L Q++ RL +
Sbjct: 330 QEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQE-RLRQQDERLWQQ 388
Query: 83 EAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 134
E L E E+ LE +L WE + + +P E L +K
Sbjct: 389 E-----TLQELERLRELERMLEL-----GWEALYEQRAEPRSGFEELNNENK 430
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 39.3 bits (90), Expect = 0.001
Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 27/137 (19%)
Query: 6 PSQNTELKVEVESLKRELQDKKQHLDKTWADVEN------LNSQNEAELRRQFEERQQET 59
PS+ +L+ E L++EL+ + L A+VEN LN + E LR Q EER +E
Sbjct: 156 PSKVEQLQDETNHLRKELESVGRQLQ---AEVENNQMLSLLNRRQEERLREQ-EERLREQ 211
Query: 60 EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPG-- 117
E L E + +L ++E RL + E E+ C EKL G + E+V
Sbjct: 212 EE--RLCEQEERLCEQEERLREQE----------ERLCE---QEKLPGQERLLEEVEKLL 256
Query: 118 DQVKPDQYTEALAQRDK 134
Q + + E L +R++
Sbjct: 257 KQERRQEEQERLLERER 273
Score = 28.9 bits (63), Expect = 1.3
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 24 QDKKQHLDKTWADVENLNSQNEA-ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN 82
Q+K ++ +VE L Q E + + ER++ + V ELLE + +L Q++ RL +
Sbjct: 239 QEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQ 297
Query: 83 EAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 134
E R E E+ LE +L WE + + +P E L +K
Sbjct: 298 ETLR-----ELERLRELERMLEL-----GWEALYEQRAEPRSGFEELNNENK 339
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 39.3 bits (90), Expect = 0.001
Identities = 43/156 (27%), Positives = 71/156 (45%), Gaps = 30/156 (19%)
Query: 6 PSQNTELKVEVESLKRELQDKKQHLDKTWADVEN------LNSQNEAELRRQFEERQQET 59
PS+ +L+ E L++EL+ + L A+VEN LN + E LR Q E ++
Sbjct: 156 PSKVEQLQDETNHLRKELESVGRQLQ---AEVENNQMLSLLNRRQEERLREQEERLHEQE 212
Query: 60 EHVYE----LLENKIQLLQEESRLAKNE-------------AARMAALVE--AEKECNLE 100
E ++E L E + +L ++E RL + E R+ E E+E L
Sbjct: 213 ERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLC 272
Query: 101 LSEKLKGVTKNWEDVPG--DQVKPDQYTEALAQRDK 134
EKL G + E+V +Q + + E L +R++
Sbjct: 273 EQEKLPGQERLLEEVEKLLEQERRQEEQERLLERER 308
Score = 33.1 bits (74), Expect = 0.069
Identities = 32/114 (28%), Positives = 56/114 (49%), Gaps = 4/114 (3%)
Query: 24 QDKKQHLDKTWADVENLNSQNEA-ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN 82
Q+K ++ +VE L Q E + + ER++ + V ELLE + +L Q++ RL +
Sbjct: 274 QEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQ 332
Query: 83 EAAR-MAALVEAEKECNLELSEKLKGVTK-NWEDVPGDQVKPDQYTEALAQRDK 134
E R + L E E+ LE +L+ + + WE + + +P E L +K
Sbjct: 333 ETLRELERLRELERLRELERLRELERMLELGWEALYEQRAEPRSGFEELNNENK 386
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 39.3 bits (90), Expect = 0.001
Identities = 29/92 (31%), Positives = 48/92 (52%), Gaps = 4/92 (4%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVY 63
E +N LK +VE+L+RELQ +++ + D EN ++ E L+ Q EE + + V+
Sbjct: 2144 ERERENDSLKDKVENLERELQMSEENQELVILDAENSKAEVET-LKTQIEEMARSLK-VF 2201
Query: 64 ELLENKIQLLQEESRLAKNEAARMAALVEAEK 95
EL + + L E+ L K + L E +K
Sbjct: 2202 EL--DLVTLRSEKENLTKQIQEKQGQLSELDK 2231
Score = 36.6 bits (83), Expect = 0.006
Identities = 30/118 (25%), Positives = 55/118 (46%), Gaps = 9/118 (7%)
Query: 4 EMPSQNTEL--------KVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEER 55
+M +N EL K EVE+LK ++++ + L D+ L S+ E L +Q +E+
Sbjct: 2164 QMSEENQELVILDAENSKAEVETLKTQIEEMARSLKVFELDLVTLRSEKE-NLTKQIQEK 2222
Query: 56 QQETEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
Q + + +LL + LL+E+ + VE + EL+E + + + E
Sbjct: 2223 QGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQE 2280
Score = 34.7 bits (78), Expect = 0.024
Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 23/117 (19%)
Query: 5 MPSQNTELKVEVESLKRELQDKKQHLDKTWAD----VENLNSQN--EAELRRQFEERQQE 58
+ S+N L+ +E L+ ++ + L+ T D VE +N E EL+R+ E Q+
Sbjct: 2572 LQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQK 2631
Query: 59 TEHVYELLENK-------IQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGV 108
T + E L + +QLL EE + +K++ KE LE SE K +
Sbjct: 2632 TAELQEELSGEKNRLAGELQLLLEEIKSSKDQL----------KELTLENSELKKSL 2678
Score = 34.3 bits (77), Expect = 0.031
Identities = 27/100 (27%), Positives = 52/100 (52%), Gaps = 9/100 (9%)
Query: 16 VESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN------K 69
++ L ++++K Q L+ ++ + EAE++ + E Q + V ELL++ K
Sbjct: 1977 LDQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEK 2036
Query: 70 IQLLQEESR---LAKNEAARMAALVEAEKECNLELSEKLK 106
+Q L+++S+ L K E A + EKE ++ SE L+
Sbjct: 2037 LQSLEKDSQALSLTKCELENQIAQLNKEKELLVKESESLQ 2076
Score = 31.2 bits (69), Expect = 0.26
Identities = 29/112 (25%), Positives = 51/112 (45%), Gaps = 13/112 (11%)
Query: 12 LKVEVESLKRELQDKKQHLDKTWADVENLNSQ-----------NEAELRRQ-FEERQQET 59
L+ V L +E++D KQ L+K ++ L +Q ++ E Q ++E+ E
Sbjct: 2499 LQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQVEGEHQLWKEQNLEL 2558
Query: 60 EHVYELLENKIQLLQ-EESRLAKNEAARMAALVEAEKECNLELSEKLKGVTK 110
++ LE KIQ+LQ + + L ++ E E L +K+ V K
Sbjct: 2559 RNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMDKMSFVEK 2610
Score = 30.0 bits (66), Expect = 0.58
Identities = 29/114 (25%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 7 SQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQ----ETEHV 62
S+N +L ++ES K LQ K HL+ T + + S E R E ++ E ++
Sbjct: 624 SENEKLLTQMESEKENLQSKINHLE-TCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNL 682
Query: 63 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLE-LSEKLKGVTKNWEDV 115
+ +L++K + E +LA E + A + + + +E + K +T ED+
Sbjct: 683 HNVLDSK-SVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVEDL 735
Score = 30.0 bits (66), Expect = 0.58
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 24/123 (19%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVEN----LNSQNEA------ELRRQFE 53
E+ T L+ +++SL+++ Q L T ++EN LN + E L+ +
Sbjct: 2025 ELLKDKTHLQEKLQSLEKD----SQALSLTKCELENQIAQLNKEKELLVKESESLQARLS 2080
Query: 54 ERQQETEHVYELLEN----------KIQLLQEESRLAKNEAARMAALVEAEKECNLELSE 103
E E +V + LE ++ QEE + ++ +EA+++ L ++E
Sbjct: 2081 ESDYEKLNVSKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAE 2140
Query: 104 KLK 106
KLK
Sbjct: 2141 KLK 2143
Score = 29.3 bits (64), Expect = 0.99
Identities = 33/148 (22%), Positives = 53/148 (35%), Gaps = 33/148 (22%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNE-----------------A 46
EM K E LK+E+ K+ +K +V +L +NE
Sbjct: 1113 EMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESE 1172
Query: 47 ELRRQFEERQQETEHV------------YELLENKIQLLQEESRLAKNEAARMAALVEAE 94
+R +ER+ E L QL+Q E+ L E + E E
Sbjct: 1173 PIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAMLRNKELKLQES--EKE 1230
Query: 95 KECNLELSEKLKG--VTKNWEDVPGDQV 120
KEC + ++G T N +D+ ++
Sbjct: 1231 KECLQHELQTIRGDLETSNLQDMQSQEI 1258
Score = 26.6 bits (57), Expect = 6.4
Identities = 21/85 (24%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 17 ESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQ-- 74
++L +E K L + +N+++ +AEL + +QQ ++ E + + Q
Sbjct: 408 QTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAF 467
Query: 75 EESRLAKNEAARMAALVEAEKECNL 99
+ S++ +NE R ++ E +KE NL
Sbjct: 468 QASQIKENELRR--SMEEMKKENNL 490
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 39.3 bits (90), Expect = 0.001
Identities = 42/137 (30%), Positives = 65/137 (47%), Gaps = 27/137 (19%)
Query: 6 PSQNTELKVEVESLKRELQDKKQHLDKTWADVEN------LNSQNEAELRRQFEERQQET 59
PS+ +L+ E L++EL+ + L A+VEN LN + E LR Q EER +E
Sbjct: 156 PSKVEQLQDETNHLRKELESVGRQLQ---AEVENNQMLSLLNRRQEERLREQ-EERLREQ 211
Query: 60 EHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPG-- 117
E L E + +L ++E RL + E E+ C EKL G + E+V
Sbjct: 212 EE--RLCEQEERLCEQEERLREQE----------ERLCE---QEKLPGQERLLEEVEKLL 256
Query: 118 DQVKPDQYTEALAQRDK 134
Q + + E L +R++
Sbjct: 257 KQERRQEEQERLLERER 273
Score = 28.9 bits (63), Expect = 1.3
Identities = 31/112 (27%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 24 QDKKQHLDKTWADVENLNSQNEA-ELRRQFEERQQETEHVYELLENKIQLLQEESRLAKN 82
Q+K ++ +VE L Q E + + ER++ + V ELLE + +L Q++ RL +
Sbjct: 239 QEKLPGQERLLEEVEKLLKQERRQEEQERLLERERLLDEVEELLEQE-RLRQQDERLWQQ 297
Query: 83 EAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDK 134
E R E E+ LE +L WE + + +P E L +K
Sbjct: 298 ETLR-----ELERLRELERMLEL-----GWEALYEQRAEPRSGFEELNNENK 339
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 38.9 bits (89), Expect = 0.001
Identities = 37/128 (28%), Positives = 64/128 (50%), Gaps = 17/128 (13%)
Query: 11 ELKVEVESLKRELQD---KKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLE 67
+L+++V SL+ EL D +K+ L+K ++ + A+ R Q EE E Y+
Sbjct: 717 QLELKVTSLEEELTDLRVEKESLEKNLSE----RKKKSAQERSQAEEEIDEIRKSYQEEL 772
Query: 68 NKIQLLQEESRLAKNE-AARMAALVEAEKECNLELS-EKLKGVTKNWEDVPGDQVKPDQY 125
+K++ L +++R++ ++ AA +LV+AE + E E L K+ QY
Sbjct: 773 DKLRQLLKKTRVSTDQAAAEQLSLVQAELQTQWEAKCEHLLASAKD--------EHLQQY 824
Query: 126 TEALAQRD 133
E AQRD
Sbjct: 825 QEVCAQRD 832
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 38.1 bits (87), Expect = 0.002
Identities = 34/110 (30%), Positives = 59/110 (53%), Gaps = 12/110 (10%)
Query: 15 EVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQ 74
++ESL RELQ++ + L+ + + + Q +A L + +R ++E + + L+ +I LQ
Sbjct: 577 QLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGD-LQARITSLQ 635
Query: 75 EESR-----LAKNEAARMAA---LVEAEKECN---LELSEKLKGVTKNWE 113
EE + L K E R A L +EKE N ++L+ KLK + + E
Sbjct: 636 EEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLE 685
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 38.1 bits (87), Expect = 0.002
Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 13/112 (11%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWAD-VENLNSQNEAELRRQFEERQQETE-- 60
E N E+ V VE K EL+ K D W + ++ L Q + E+ + E+ +QE E
Sbjct: 597 EKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETL 656
Query: 61 ----------HVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELS 102
H+ E+ E ++ L + ++ ++ ++ +++A + ELS
Sbjct: 657 LKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELS 708
Score = 36.6 bits (83), Expect = 0.006
Identities = 40/163 (24%), Positives = 74/163 (45%), Gaps = 36/163 (22%)
Query: 3 YEMPSQNTE--LKVEVESLKRELQDKKQHLDKTWADVENLNS---QNEAELRRQ------ 51
+E+ Q TE LK ++ L+ L+++ +HL + A VENL + ++E EL++
Sbjct: 743 HEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDV 802
Query: 52 FEERQQETEHVYELLENKIQLLQEESRLAKNE---AARMAALVEAEKE--C--------- 97
F+ Q T + E ++ LQ++ + E + A VEA+K+ C
Sbjct: 803 FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQ 862
Query: 98 -----------NLELSEKLKGVTKNWEDVPGDQVKPDQYTEAL 129
N E+ +K+K +T+ +E D K + T+ +
Sbjct: 863 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQI 905
Score = 35.0 bits (79), Expect = 0.018
Identities = 22/103 (21%), Positives = 53/103 (51%), Gaps = 1/103 (0%)
Query: 4 EMPSQNTELKVEVESLKRELQDK-KQHLDKTWADVENLNSQNEAELRRQFEERQQETEHV 62
E+ + EL ++++ +RE Q++ K L+K+ ++ ++ + E + EE + + + +
Sbjct: 488 ELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAI 547
Query: 63 YELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKL 105
ENK++ LQ+E+ + + + +E + N S+ L
Sbjct: 548 LTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 590
Score = 34.3 bits (77), Expect = 0.031
Identities = 30/132 (22%), Positives = 63/132 (47%), Gaps = 10/132 (7%)
Query: 5 MPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYE 64
+ +Q +K E+E+ K+EL+ + +++ L + E+E + E +++ E
Sbjct: 1590 LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIA 1649
Query: 65 LLENKI--QLLQEESRLAKNEAARMA----ALVEAEKECNLELSEKLKGVTKNWED---V 115
++ ++ Q+ ++E + K + ++ L E E+E ++ L EKLK V + + V
Sbjct: 1650 AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHI-LEEKLKSVESSQSETLIV 1708
Query: 116 PGDQVKPDQYTE 127
P YTE
Sbjct: 1709 PRSAKNVAAYTE 1720
Score = 33.5 bits (75), Expect = 0.052
Identities = 23/110 (20%), Positives = 52/110 (47%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVY 63
E+ +Q ++ E+++ K ++QD Q L+K +++E + E+ +E E
Sbjct: 844 EVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTK 903
Query: 64 ELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWE 113
++L K ++ + K E + + A+++ L+E+ + KN E
Sbjct: 904 QILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQE 953
Score = 32.0 bits (71), Expect = 0.15
Identities = 26/107 (24%), Positives = 50/107 (46%), Gaps = 13/107 (12%)
Query: 9 NTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLEN 68
N+ LK + +L K+Q L+ T + N + EAEL E Q+ET +
Sbjct: 1991 NSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAEL---LESHQEETNQL------ 2041
Query: 69 KIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDV 115
++ + E+ K A R +++A +E E++ K++ + E++
Sbjct: 2042 -LKKIAEKDDDLKRTAKRYEEILDAREE---EMTAKVRDLQTQLEEL 2084
Score = 31.2 bits (69), Expect = 0.26
Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 36/143 (25%)
Query: 8 QNTELKVEVESLKRELQDKKQHLDKT--------------WADVENLNSQNE-------A 46
Q T L E E+L+ +L ++ Q L+K D +NL Q E A
Sbjct: 308 QCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA 367
Query: 47 ELRRQFEERQQETEHVYELLENKIQLLQ---EESRLAKNEAARMA------------ALV 91
E +RQ E + E L ++I+ + EE R K ++ R A
Sbjct: 368 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTE 427
Query: 92 EAEKECNLELSEKLKGVTKNWED 114
EA ++ E+ E++K + K E+
Sbjct: 428 EARRKLKAEMDEQIKTIEKTSEE 450
Score = 26.9 bits (58), Expect = 4.9
Identities = 25/112 (22%), Positives = 51/112 (45%), Gaps = 11/112 (9%)
Query: 4 EMPSQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVY 63
+M +Q EL+ + E +R ++ + T E + +AE+ Q + ++ +E
Sbjct: 393 QMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSE--- 449
Query: 64 ELLENKIQLLQEESRLAKN-----EAARMAALVEAEKECNLELSEKLKGVTK 110
E +I L QE SR+ + + + + + +K EL+ K + +TK
Sbjct: 450 ---EERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTK 498
>gi|196115290 glial fibrillary acidic protein isoform 2 [Homo
sapiens]
Length = 431
Score = 37.7 bits (86), Expect = 0.003
Identities = 28/82 (34%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 7 SQNTELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYEL- 65
++N EL + K E D ++ L D+E+L NE+ L RQ R+QE HV E
Sbjct: 269 ARNAEL---LRQAKHEANDYRRQLQSLTCDLESLRGTNES-LERQM--REQEERHVREAA 322
Query: 66 -LENKIQLLQEESRLAKNEAAR 86
+ + L+EE + K+E AR
Sbjct: 323 SYQEALARLEEEGQSLKDEMAR 344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.123 0.329
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,612,466
Number of Sequences: 37866
Number of extensions: 179627
Number of successful extensions: 2766
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 286
Number of HSP's successfully gapped in prelim test: 447
Number of HSP's that attempted gapping in prelim test: 1445
Number of HSP's gapped (non-prelim): 1607
length of query: 134
length of database: 18,247,518
effective HSP length: 91
effective length of query: 43
effective length of database: 14,801,712
effective search space: 636473616
effective search space used: 636473616
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.