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Search of human proteins with 87298939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
(663 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|87298939 hypothetical protein LOC131831 [Homo sapiens] 1321 0.0
gi|210147567 hypothetical protein LOC220081 [Homo sapiens] 94 5e-19
gi|17975763 myelin transcription factor 1 [Homo sapiens] 71 4e-12
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 69 1e-11
gi|68163572 hypothetical protein LOC84077 [Homo sapiens] 67 4e-11
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 66 1e-10
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 66 1e-10
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 63 1e-09
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 62 1e-09
gi|21735415 centromere protein B [Homo sapiens] 60 5e-09
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 60 5e-09
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 60 5e-09
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 60 6e-09
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 60 6e-09
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 58 3e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 58 3e-08
gi|118600967 shroom family member 4 [Homo sapiens] 57 4e-08
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 57 5e-08
gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 57 5e-08
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 57 7e-08
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 57 7e-08
gi|215422388 death-domain associated protein isoform a [Homo sap... 57 7e-08
gi|215422366 death-domain associated protein isoform b [Homo sap... 57 7e-08
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 56 1e-07
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 56 1e-07
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 56 1e-07
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 56 1e-07
gi|221219020 NYD-SP11 protein [Homo sapiens] 55 2e-07
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 55 3e-07
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 55 3e-07
>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
Length = 663
Score = 1321 bits (3420), Expect = 0.0
Identities = 663/663 (100%), Positives = 663/663 (100%)
Query: 1 MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEEL 60
MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEEL
Sbjct: 1 MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEEL 60
Query: 61 VGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTE 120
VGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTE
Sbjct: 61 VGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTE 120
Query: 121 TPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWLQDLSD 180
TPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWLQDLSD
Sbjct: 121 TPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWLQDLSD 180
Query: 181 KVQSRKKASKEKAEPECLASKLREKWVINPEESKLNILYELEFKEDFITLFEPSLRTLPS 240
KVQSRKKASKEKAEPECLASKLREKWVINPEESKLNILYELEFKEDFITLFEPSLRTLPS
Sbjct: 181 KVQSRKKASKEKAEPECLASKLREKWVINPEESKLNILYELEFKEDFITLFEPSLRTLPS 240
Query: 241 IGPPSILAYKEESSNLGINFKDEEEETSPKCEFCGSDLRAFFSNVDVSSEPKGHASCCIA 300
IGPPSILAYKEESSNLGINFKDEEEETSPKCEFCGSDLRAFFSNVDVSSEPKGHASCCIA
Sbjct: 241 IGPPSILAYKEESSNLGINFKDEEEETSPKCEFCGSDLRAFFSNVDVSSEPKGHASCCIA 300
Query: 301 FQNLIDYIYEEQIKTKPPKAELIAIDPHAAHGSEVDRLKAKEKALQRKQEQRMARHFAII 360
FQNLIDYIYEEQIKTKPPKAELIAIDPHAAHGSEVDRLKAKEKALQRKQEQRMARHFAII
Sbjct: 301 FQNLIDYIYEEQIKTKPPKAELIAIDPHAAHGSEVDRLKAKEKALQRKQEQRMARHFAII 360
Query: 361 SREQTHFSEDDSKRLKTISYQLSVDIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKV 420
SREQTHFSEDDSKRLKTISYQLSVDIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKV
Sbjct: 361 SREQTHFSEDDSKRLKTISYQLSVDIPEKQIIDDIVFDFQLRNSNMSIICCDSRIACGKV 420
Query: 421 VRNELLEKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQEDMPTNPAI 480
VRNELLEKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQEDMPTNPAI
Sbjct: 421 VRNELLEKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQEDMPTNPAI 480
Query: 481 LAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFL 540
LAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFL
Sbjct: 481 LAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFL 540
Query: 541 ALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASL 600
ALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASL
Sbjct: 541 ALNRYIGVRILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASL 600
Query: 601 IKIRRLFHKLEGCVNFPSSQVWEKLKQPSYLSSLSLKLIALCHSSGIKQDIMKTIRNIIN 660
IKIRRLFHKLEGCVNFPSSQVWEKLKQPSYLSSLSLKLIALCHSSGIKQDIMKTIRNIIN
Sbjct: 601 IKIRRLFHKLEGCVNFPSSQVWEKLKQPSYLSSLSLKLIALCHSSGIKQDIMKTIRNIIN 660
Query: 661 EEI 663
EEI
Sbjct: 661 EEI 663
>gi|210147567 hypothetical protein LOC220081 [Homo sapiens]
Length = 696
Score = 93.6 bits (231), Expect = 5e-19
Identities = 63/210 (30%), Positives = 111/210 (52%), Gaps = 7/210 (3%)
Query: 430 YKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQEDMPTNPAILAVLDSSGR 489
Y + + + FPDGT QI YPSGNLA++ + K+ FT I+ ED I A++++SG
Sbjct: 480 YPNKNVYQILFPDGTGQIHYPSGNLAMLILYAKMKKFTYIILED-SLEGRIRALINNSGN 538
Query: 490 SSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFLALNRYIGVR 549
++ Y N ++W+ ++ G Y + R +AWNW N +P+ L +N YI V+
Sbjct: 539 ATFYDENSDIWLNLSSNLGYYFPK-DKRQKAWNWWNLNIHVHAPPVQPISLKINEYIQVQ 597
Query: 550 ILEQDKISITFLAMGQQARISVGTKVKLPNPEEIPILRYVSGDDLLLLASLIKIRRLFHK 609
I QDKI F +Q +++GT+ K PE + ++ + + + KIR L K
Sbjct: 598 IRSQDKIIFCFTYEQKQICLNLGTRYKFVIPEVLSEMKKKTILEAEPGPTAQKIRVLLGK 657
Query: 610 LEGCVNFPSSQVWEKLKQPSYLSSLSLKLI 639
+ +N+ ++ E +++ ++S+ L+
Sbjct: 658 MNRLLNYATTPDLE-----NFIEAVSISLM 682
Score = 53.9 bits (128), Expect = 5e-07
Identities = 58/235 (24%), Positives = 104/235 (44%), Gaps = 19/235 (8%)
Query: 3 HLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEE---EEVEEEEEEVEEEEEEVVEEE 59
HL G G ++++ EE++ ++ +EEEE ++ EEE+ E+EE + EEE
Sbjct: 133 HLEEEEYLGKEGYLEKEDYIEEVDYLGKKAYLEEEEYLGKKSYLEEEKALEKEENLEEEE 192
Query: 60 LVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTF--VPSQSAT 117
+ +E+ L+ E ++YL + Y +R + PS +TF VP A
Sbjct: 193 ALEKEENLDGKENLYKKYLKEPK--ASYSSQTMLLRDARSPDAGPSQVTTFLTVPLTFA- 249
Query: 118 STETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWL-- 175
TPS S+T S + +++ + ++ DR ++L +T
Sbjct: 250 ---TPSPVSESATESSELLLTLYRRSQASQTDWCYDRTAVKSLKSKSETEQETTTKLAPE 306
Query: 176 QDLSDKVQSRKK------ASKEKAEPECLASKLREKWVINPEESKLNILYELEFK 224
+ ++ KVQ +K+ ASKE + + V + +E+ LN Y+ FK
Sbjct: 307 EHVNTKVQQKKEENVLEFASKENFWDGITDESIDKLEVEDLDENFLNSSYQTVFK 361
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/74 (44%), Positives = 44/74 (59%), Gaps = 7/74 (9%)
Query: 14 GKKDQKESEEELEEE---EEEEEVEEEE---EEVEEEEEEVEEEEEEVVEEELVGEEQEL 67
GK++ E EE LE+ EEEE +EEEE +E EEEE +EE + EEE +G+E L
Sbjct: 87 GKEEHLEEEEYLEKAGYLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYL 146
Query: 68 EAPETFSE-EYLWK 80
E + E +YL K
Sbjct: 147 EKEDYIEEVDYLGK 160
Score = 44.7 bits (104), Expect = 3e-04
Identities = 42/114 (36%), Positives = 55/114 (48%), Gaps = 29/114 (25%)
Query: 4 LRSPSGFGDPGK----KDQKESEEELEEEE--------EEEEVEEEEEEVEEEE------ 45
L+ S F G+ K+ E EE+LEEEE +EEE +EE +EEEE
Sbjct: 43 LQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLGKEEHLEEEEYLEKAG 102
Query: 46 ----EEVEEEEE------EVVEEELVGEEQELEAPETFSEE-YLWKVTDIGDYD 88
EE EEEE + EEE +G+E+ LE E +E YL K I + D
Sbjct: 103 YLEEEEYIEEEEYLGKEGYLEEEEYLGKEEHLEEEEYLGKEGYLEKEDYIEEVD 156
Score = 42.4 bits (98), Expect = 0.001
Identities = 24/64 (37%), Positives = 40/64 (62%), Gaps = 5/64 (7%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
+++++E EL+EE ++E E E++E EEEE++ EEE +G+E+ L+ EE
Sbjct: 30 EKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLK-----EEE 84
Query: 77 YLWK 80
YL K
Sbjct: 85 YLGK 88
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/78 (41%), Positives = 44/78 (56%), Gaps = 15/78 (19%)
Query: 13 PGKKDQKE---SEEELEEEEE---EEEVEEEEEEVEEEEEEVEEE----EEEVVEEELVG 62
P +K+ E EE L++E E E E++E +EEEE+ EEE EE + EEE +G
Sbjct: 28 PSEKEDTEVELDEESLQDESPFSPEGESLEDKEYLEEEEDLEEEEYLGKEEYLKEEEYLG 87
Query: 63 EEQELEAPETFSEEYLWK 80
+E+ LE EEYL K
Sbjct: 88 KEEHLE-----EEEYLEK 100
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 70.9 bits (172), Expect = 4e-12
Identities = 38/63 (60%), Positives = 44/63 (69%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73
G +E +EE EEEEEEEE +EEEEE EEEEEE EEEEEE EEE EE+E AP+
Sbjct: 253 GILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVI 312
Query: 74 SEE 76
+E
Sbjct: 313 FQE 315
Score = 70.1 bits (170), Expect = 6e-12
Identities = 38/59 (64%), Positives = 42/59 (71%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
++E EEE EEEEEEEE EEEEEE EEEEEE EEEEEE EEE EE+E F E+
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQED 316
Score = 65.5 bits (158), Expect = 2e-10
Identities = 53/171 (30%), Positives = 72/171 (42%), Gaps = 6/171 (3%)
Query: 7 PSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQE 66
P D ++ + + L EEE+EE EEEEEE EE+EEE EEEEEE EEE EE+E
Sbjct: 237 PQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 296
Query: 67 LEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLT---STFVPSQSATSTETPS 123
E E EE V D P L SPS S V +S + +
Sbjct: 297 EEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDT 356
Query: 124 ASPPSSTSSHKSFPKIFQTFRKDMSEMSI---DRNIHRNLSPGIPVSVQTE 171
S S+ + + + E +I + PG P + Q++
Sbjct: 357 HSRKSTVTDESEMQDMMTRGNLGLLEQAIALKAEQVRTVCEPGCPPAEQSQ 407
Score = 40.8 bits (94), Expect = 0.004
Identities = 24/62 (38%), Positives = 34/62 (54%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
++ Q + LE+ EE +++ EEE+E EEEEEE EE+ EE+E E E
Sbjct: 230 ERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEE 289
Query: 75 EE 76
EE
Sbjct: 290 EE 291
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 69.3 bits (168), Expect = 1e-11
Identities = 71/217 (32%), Positives = 101/217 (46%), Gaps = 26/217 (11%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
D +++++E EEE EEEEEEEE EEEEE EEE E EEEEEE EEE EE ELE E
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 72 ----TFSEEYLWKVTDI------GDYDDDFPDVRPRLASIVSPSLTSTFVPSQ------- 114
EE L +V D+ G+ ++ P P L + P + V +
Sbjct: 947 EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPP-PPTLPPALPPPESPPKVQPEPEPEPGL 1005
Query: 115 ----SATSTETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHR-NLSPGIPVSVQ 169
TE + + T + ++ P + R+ S + P P ++
Sbjct: 1006 LLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLL 1065
Query: 170 TEESWLQDLSDKVQSRKKA-SKEKAEPECLASKLREK 205
EE+ +D SDKVQ + ++E+ E E A L+EK
Sbjct: 1066 EEET--EDGSDKVQPPPETPAEEEMETETEAEALQEK 1100
Score = 68.2 bits (165), Expect = 2e-11
Identities = 41/77 (53%), Positives = 48/77 (62%), Gaps = 9/77 (11%)
Query: 6 SPSGFGDPGKKDQ------KESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
+P G G P ++ S+EE EEEEEEEE EEEEEE EE+ EE EE+EEE EEE
Sbjct: 865 TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEE 924
Query: 60 LVGEEQELEAPETFSEE 76
EE+E E E F EE
Sbjct: 925 ---EEEEEEFEEEFEEE 938
Score = 36.2 bits (82), Expect = 0.099
Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 1/47 (2%)
Query: 31 EEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEY 77
EE++ +EEEE EEEEEE EEE EE++ E E EEY
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEE-EEEEEDFEEEEEDEEEY 920
Score = 30.4 bits (67), Expect = 5.5
Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 3/71 (4%)
Query: 23 EELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKVT 82
+EL EEE EEE E+ ++V+ E EEE+ E E EA +E
Sbjct: 1051 QELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEM---ETETEAEALQEKEQDDTAA 1107
Query: 83 DIGDYDDDFPD 93
+ D+ D PD
Sbjct: 1108 MLADFIDCPPD 1118
>gi|68163572 hypothetical protein LOC84077 [Homo sapiens]
Length = 904
Score = 67.4 bits (163), Expect = 4e-11
Identities = 41/146 (28%), Positives = 80/146 (54%), Gaps = 12/146 (8%)
Query: 431 KHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNG--FTCIVQEDMPTNPAILAVLDSSG 488
K KF +F DG++ ++YPSGN+A+ ++P G TC+ D+P ++LAV ++ G
Sbjct: 370 KKAFKFHYTFYDGSSFVYYPSGNVAVCQIPTCCRGRTVTCLF-NDIP-GFSLLAVFNTEG 427
Query: 489 RSSCYHPNGNVWVYINIL---GGQYSDQAGNRIRAWNWSNSITSSPFVSFKPVFLALNRY 545
+ ++ Y+ IL GG +DQ G + W+W++ + + +K +N
Sbjct: 428 QGCVHYNLKTSCPYVLILDEEGGTTNDQQGYVVHKWSWTSRTETLLSLEYK-----VNEE 482
Query: 546 IGVRILEQDKISITFLAMGQQARISV 571
+ +++L QD I++TF ++ + ++V
Sbjct: 483 MKLKVLGQDSITVTFTSLNETVTLTV 508
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 65.9 bits (159), Expect = 1e-10
Identities = 32/50 (64%), Positives = 39/50 (78%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE 63
GK++++E EE+ EEEEE+EE EEEEEE EEEEEE EEEEEE +GE
Sbjct: 731 GKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGE 780
Score = 60.1 bits (144), Expect = 6e-09
Identities = 33/47 (70%), Positives = 36/47 (76%), Gaps = 2/47 (4%)
Query: 13 PGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
P ++E EEE E+EEEEEE EEEEEE EEEEEE EEEEEE EEE
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEE--EEE 771
Score = 59.3 bits (142), Expect = 1e-08
Identities = 31/47 (65%), Positives = 34/47 (72%)
Query: 13 PGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
P + EEE EEEE+EEE EE+EEE EEEEEE EEEEEE EEE
Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEE 770
Score = 58.2 bits (139), Expect = 2e-08
Identities = 34/50 (68%), Positives = 35/50 (70%), Gaps = 2/50 (4%)
Query: 26 EEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSE 75
EEEEEEEE EEEEEE EEEEEE EEEEEE EEE EE+E A E
Sbjct: 733 EEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEE--EEEEEAAAAVALGE 780
Score = 57.4 bits (137), Expect = 4e-08
Identities = 29/50 (58%), Positives = 35/50 (70%)
Query: 7 PSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVV 56
P G +++++E EEE EE+EEEEE EEEEEE EEEEEE EEE V
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAV 776
Score = 56.2 bits (134), Expect = 9e-08
Identities = 31/44 (70%), Positives = 35/44 (79%), Gaps = 3/44 (6%)
Query: 26 EEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEA 69
+EEEEEEE +EEEEE +EEEEE EEEEEE EEE EE+E EA
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEE---EEEEEEA 772
Score = 54.7 bits (130), Expect = 3e-07
Identities = 27/48 (56%), Positives = 36/48 (75%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVG 62
++++++ EEE E+EEEEEE EEEEEE EEEEEE EE V E++G
Sbjct: 736 EEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLG 783
Score = 49.3 bits (116), Expect = 1e-05
Identities = 29/57 (50%), Positives = 36/57 (63%)
Query: 25 LEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKV 81
++ + +E EEEEEE EEEEEE EEEEEE EEE EE+E E E + L +V
Sbjct: 725 VQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEV 781
Score = 42.7 bits (99), Expect = 0.001
Identities = 32/82 (39%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 38 EEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPR 97
+EE EEEEE+ EEEEE+ EEE EE+E E E EE +G+ + PR
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEV------LGPR 785
Query: 98 LASIVSPSLTSTFVPSQSATST 119
S S ST + A ST
Sbjct: 786 SGSSSEGSERSTDRSQEGAPST 807
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 65.9 bits (159), Expect = 1e-10
Identities = 39/62 (62%), Positives = 44/62 (70%), Gaps = 1/62 (1%)
Query: 17 DQKE-SEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSE 75
D KE SEEE E E+EEEEVE+EEEE EE E VEE EEE+ EEEL EE+ LE E E
Sbjct: 296 DAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGE 355
Query: 76 EY 77
E+
Sbjct: 356 EF 357
Score = 58.2 bits (139), Expect = 2e-08
Identities = 38/68 (55%), Positives = 44/68 (64%), Gaps = 11/68 (16%)
Query: 20 ESEEELEEEEEEE---------EVEEEEEEVEEEEEEVEEEEEEVVEE-ELVGE-EQELE 68
E EEE + ++EEE E EEEEEVE+EEEEVE+EEEE VEE E V E E+ELE
Sbjct: 277 EEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELE 336
Query: 69 APETFSEE 76
E EE
Sbjct: 337 EEELEEEE 344
Score = 54.3 bits (129), Expect = 4e-07
Identities = 34/63 (53%), Positives = 40/63 (63%), Gaps = 12/63 (19%)
Query: 16 KDQKESEEELEEEEEEEEVEEEEEEVEE-----------EEEEVEEEEEEVVEEELVGEE 64
K+ E EEE+E+EEEE E +EEEEEVEE EEEE+EEEEE + E E GEE
Sbjct: 298 KEASEEEEEVEDEEEEVE-DEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
Query: 65 QEL 67
L
Sbjct: 357 FHL 359
Score = 32.0 bits (71), Expect = 1.9
Identities = 21/44 (47%), Positives = 25/44 (56%), Gaps = 3/44 (6%)
Query: 19 KESEEELEEEE---EEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
+E EEELEEEE EEE +EE E+ EE +E VE E
Sbjct: 329 EEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMPLSIFVEAE 372
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 62.8 bits (151), Expect = 1e-09
Identities = 38/75 (50%), Positives = 46/75 (61%), Gaps = 6/75 (8%)
Query: 3 HLRSPSGFGDPGKKDQ-----KESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVE 57
+L SP G++ Q KES EE EEEEE+EE EEEEEE EE+EEE EEEEEE E
Sbjct: 1045 YLHSPESRPVTGERGQLLELSKESSEE-EEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEE 1103
Query: 58 EELVGEEQELEAPET 72
E + L P++
Sbjct: 1104 ENIQSSPPRLTKPQS 1118
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/65 (47%), Positives = 41/65 (63%), Gaps = 1/65 (1%)
Query: 13 PGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVG-EEQELEAPE 71
P ++ E++L + EEEEE EEEEEE EEEEE EEE VE++ G + QE E PE
Sbjct: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPE 1394
Query: 72 TFSEE 76
+E+
Sbjct: 1395 ISTEK 1399
Score = 50.1 bits (118), Expect = 7e-06
Identities = 23/47 (48%), Positives = 33/47 (70%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELV 61
++++ E EEE EEEEEE+E EEEEEE EEEEE ++ + + + V
Sbjct: 1073 EEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/88 (35%), Positives = 45/88 (51%), Gaps = 18/88 (20%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEE-------------EVEEEEEEVEEEEEEVVEEELV 61
K +++E EEE EEEEEEEE EEEE E+EE E+ E+E+ +
Sbjct: 1349 KPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDH 1408
Query: 62 GEEQELEAPETFSEEYLWKVTDIGDYDD 89
EE+E + + +E++ D D DD
Sbjct: 1409 EEEEEEDEEPSHNEDH-----DADDEDD 1431
Score = 42.0 bits (97), Expect = 0.002
Identities = 24/48 (50%), Positives = 29/48 (60%)
Query: 29 EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
E + +E +E EEEEEE +EEEEE EEE EE+E E E EE
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 1104
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/48 (37%), Positives = 31/48 (64%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
D +++++E EEE EEEEEEEE EEEEE ++ + + + ++ +
Sbjct: 1077 DEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRK 1124
Score = 40.8 bits (94), Expect = 0.004
Identities = 23/61 (37%), Positives = 35/61 (57%), Gaps = 2/61 (3%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE--EQELEAPET 72
K+D ++ EEEEE+EE E+ ++E++ E EV +EEL E ++ LE ET
Sbjct: 1399 KEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQET 1458
Query: 73 F 73
F
Sbjct: 1459 F 1459
Score = 38.9 bits (89), Expect = 0.015
Identities = 25/62 (40%), Positives = 31/62 (50%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
K S E E ++ E +E EEEEE E+EEEE EEE +E+E E E
Sbjct: 1042 KNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE 1101
Query: 75 EE 76
EE
Sbjct: 1102 EE 1103
Score = 38.9 bits (89), Expect = 0.015
Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 4/65 (6%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
D K +KE E E+E+ +++ EEE EE+EE E+ + +E ++ +E+ E
Sbjct: 1383 DGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDE----DDSHMESAE 1438
Query: 72 TFSEE 76
EE
Sbjct: 1439 VEKEE 1443
Score = 33.5 bits (75), Expect = 0.64
Identities = 65/289 (22%), Positives = 106/289 (36%), Gaps = 48/289 (16%)
Query: 20 ESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLW 79
+S+ + E V E ++ E +E EEEEE +EE EE+E E E EE
Sbjct: 1040 QSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEE--- 1096
Query: 80 KVTDIGDYDDDFPDVRPRLASIVSPSL--TSTFVPSQ----------SATSTETPSAS-- 125
+ + +++ PRL S ++ FV + S+ +TET S +
Sbjct: 1097 --EEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTE 1154
Query: 126 ----PPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEESWLQD---- 177
P ++ + P++ T ++ E + + QTEE +D
Sbjct: 1155 VLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCF 1214
Query: 178 ---------LSDKVQSRKKASKEKAEP-ECL------ASKLREKWVINPEES---KLNIL 218
++D + K+ SK+ EP +C + KW N E KLN+
Sbjct: 1215 KNADPCRNNMNDDSSNLKEGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLY 1274
Query: 219 Y--ELEFKEDFITLFEPSLRTLPSIGPPSILAYKEESSNLGINFKDEEE 265
E + D E T PS + +EE G +EE
Sbjct: 1275 TPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEE 1323
Score = 32.0 bits (71), Expect = 1.9
Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 6/88 (6%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQ----ELEAP 70
+++ +E EEE EEEEEEE ++ + + + + + V ++ G ++
Sbjct: 1087 EEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTT 1146
Query: 71 ETFSE--EYLWKVTDIGDYDDDFPDVRP 96
ET SE E L + D D + P + P
Sbjct: 1147 ETISETTEVLNEPFDNSDEERPMPQLEP 1174
Score = 31.2 bits (69), Expect = 3.2
Identities = 27/70 (38%), Positives = 38/70 (54%), Gaps = 17/70 (24%)
Query: 15 KKDQKESEEEL--EEEEEEEEV-----------EEEEEEVEEEEEEVEEEEEEVVEEELV 61
+++ KE+ E L +EE EE E+ E+++ + EEE EEEEEE EEE
Sbjct: 1308 EEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEE-EEEEEEEEEEE-- 1364
Query: 62 GEEQELEAPE 71
EE+E E E
Sbjct: 1365 -EEEEGEEEE 1373
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 62.4 bits (150), Expect = 1e-09
Identities = 44/89 (49%), Positives = 54/89 (60%), Gaps = 8/89 (8%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G D G D +SEEE EEEEE+EE EEEEE+ EEEEEE EEEEE+ EE L L+
Sbjct: 847 GVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEE-EEEEEKGNEEPL-----SLD 900
Query: 69 APETFSEE--YLWKVTDIGDYDDDFPDVR 95
PET ++ YL+ + + PDVR
Sbjct: 901 WPETRQKQAIYLFLLPIVFPLWLTVPDVR 929
Score = 45.4 bits (106), Expect = 2e-04
Identities = 22/42 (52%), Positives = 30/42 (71%)
Query: 6 SPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEE 47
S G + +++++E EEE EEEE+EEE EEEEEE E+ EE
Sbjct: 854 SDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/72 (38%), Positives = 41/72 (56%), Gaps = 6/72 (8%)
Query: 11 GDPGKKDQKE--SEEELEEEEEEEEVEE----EEEEVEEEEEEVEEEEEEVVEEELVGEE 64
G+ G+ + +E +E E + +E+ VE+ + + EEEEEE EE+EEE EEE EE
Sbjct: 823 GNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEE 882
Query: 65 QELEAPETFSEE 76
+E E E E
Sbjct: 883 EEEEEEEEKGNE 894
Score = 40.0 bits (92), Expect = 0.007
Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 12/76 (15%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEV------------EEEEEEVEEEEEEVVEEELVG 62
K ++ E+E + E E + +E+ V EEEEEE E+EEEE EE+
Sbjct: 822 KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE 881
Query: 63 EEQELEAPETFSEEYL 78
EE+E E E +EE L
Sbjct: 882 EEEEEEEEEKGNEEPL 897
Score = 37.0 bits (84), Expect = 0.058
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 1/65 (1%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE-ELVGEEQELEAPET 72
G + Q E E E E + + EE E+E E + + E E+E E E+ E+ G E E E+ E
Sbjct: 774 GGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQEL 833
Query: 73 FSEEY 77
+E +
Sbjct: 834 SAENH 838
Score = 33.5 bits (75), Expect = 0.64
Identities = 20/61 (32%), Positives = 32/61 (52%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G P + + E++ + EE E+E E E + + E+E E+ E+ E+ E E QEL
Sbjct: 775 GETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELS 834
Query: 69 A 69
A
Sbjct: 835 A 835
Score = 31.2 bits (69), Expect = 3.2
Identities = 31/106 (29%), Positives = 41/106 (38%), Gaps = 36/106 (33%)
Query: 7 PSGFGDP---GKKDQKESEEELE-----EEEEEEEVEEEEEEVEEEEEEVEEEE------ 52
P G G+ GK ++ E E E E E E+E E+ E+ E++ E E E +E
Sbjct: 779 PEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENH 838
Query: 53 ----------------------EEVVEEELVGEEQELEAPETFSEE 76
EE EEE EE+E E E EE
Sbjct: 839 GEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEE 884
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 60.5 bits (145), Expect = 5e-09
Identities = 35/49 (71%), Positives = 39/49 (79%), Gaps = 1/49 (2%)
Query: 20 ESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
+SE E EEEEEEEE EEEE E EEEEEE EEEEEE E E +GEE+E+E
Sbjct: 402 KSEGE-EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE 449
Score = 58.2 bits (139), Expect = 2e-08
Identities = 40/70 (57%), Positives = 44/70 (62%), Gaps = 6/70 (8%)
Query: 15 KKDQKESEEELEEEEEEE-EVEEEEEEVEEEEEEVEE-----EEEEVVEEELVGEEQELE 68
K + +E EEE EEEEEEE E EEEEEE EEEEEE E EEEEV EE V ++E E
Sbjct: 402 KSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEE 461
Query: 69 APETFSEEYL 78
E S E L
Sbjct: 462 EDEESSSEGL 471
Score = 53.1 bits (126), Expect = 8e-07
Identities = 32/65 (49%), Positives = 43/65 (66%), Gaps = 3/65 (4%)
Query: 14 GKKDQKESEEELEEE---EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G+++++E EEE EEE EEEEE EEEEE E EE+ EEEE E ++ +E+E E
Sbjct: 405 GEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDE 464
Query: 71 ETFSE 75
E+ SE
Sbjct: 465 ESSSE 469
Score = 48.9 bits (115), Expect = 1e-05
Identities = 32/69 (46%), Positives = 37/69 (53%), Gaps = 18/69 (26%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEE------------------VEEEEEEVVEEE 59
++E EEE EEEEEE E EEEEEE EEEEEE V+ +EEE +EE
Sbjct: 406 EEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEE 465
Query: 60 LVGEEQELE 68
E E E
Sbjct: 466 SSSEGLEAE 474
Score = 47.0 bits (110), Expect = 6e-05
Identities = 34/86 (39%), Positives = 48/86 (55%), Gaps = 6/86 (6%)
Query: 4 LRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEE----EEVEEEEEEVEEEEEEVVEEE 59
L+S + +++++E E E EEEEEE E EEEE EE+ EEEE EE + + EEE
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE 460
Query: 60 LVGEEQELEAPETFSEEYLWKVTDIG 85
EE E E +E++ V + G
Sbjct: 461 EEDEESSSEGLE--AEDWAQGVVEAG 484
Score = 45.1 bits (105), Expect = 2e-04
Identities = 28/57 (49%), Positives = 33/57 (57%)
Query: 34 VEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDD 90
++ E EE EEEEEE EEEE E EEE GEE+E E E +V + GD D D
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSD 457
Score = 32.3 bits (72), Expect = 1.4
Identities = 13/39 (33%), Positives = 27/39 (69%)
Query: 10 FGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEV 48
F + G+ +SEEE +EEE++E+ +++++E + +E V
Sbjct: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPV 541
Score = 32.3 bits (72), Expect = 1.4
Identities = 12/34 (35%), Positives = 25/34 (73%)
Query: 20 ESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEE 53
E E+ + + EEE+ EEE++E E+++++ E+ +E
Sbjct: 505 EGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 31.6 bits (70), Expect = 2.5
Identities = 16/51 (31%), Positives = 30/51 (58%)
Query: 28 EEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYL 78
E+ + + EEE++E E++E+E ++++EE +E V E A + YL
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGEAMAYFAMVKRYL 558
Score = 31.2 bits (69), Expect = 3.2
Identities = 12/32 (37%), Positives = 24/32 (75%)
Query: 24 ELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEV 55
E + + EEE +EEE++ +E++++ EE+ +EV
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
Score = 30.4 bits (67), Expect = 5.5
Identities = 12/38 (31%), Positives = 25/38 (65%)
Query: 26 EEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE 63
+ + + EE ++EEE+ E+E+++ +EE+ + V GE
Sbjct: 509 DSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPVPSFGE 546
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 60.5 bits (145), Expect = 5e-09
Identities = 31/48 (64%), Positives = 36/48 (75%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEE 64
D ++ EEE E EEEEEE EEEEEE EEEEEE EEEEEE ++ GE+
Sbjct: 359 DDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEK 406
Score = 56.2 bits (134), Expect = 9e-08
Identities = 51/152 (33%), Positives = 71/152 (46%), Gaps = 13/152 (8%)
Query: 21 SEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWK 80
S++E EEEEEE E EEEE E EEEE+E EEEEEE EEE + + E T S + L
Sbjct: 358 SDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKIL-- 415
Query: 81 VTDIGDYDDDFPDVRPRLASIVSPSLTSTFV--PSQSATSTETPSASPPSSTSSHKSFP- 137
D + + P L+S P+ STF+ PS P +S + + S P
Sbjct: 416 -------DPNTGEPAPVLSS-PPPADVSTFLAFPSPEKLLRLGPKSSVLIAQQTDTSDPE 467
Query: 138 KIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQ 169
K+ F K S + + + + +Q
Sbjct: 468 KVVSAFLKVSSVFKDEATVRMAVQDAVDALMQ 499
Score = 53.1 bits (126), Expect = 8e-07
Identities = 26/39 (66%), Positives = 31/39 (79%)
Query: 16 KDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEE 54
+D++E EE EEEEE EE EEE+EE EEEEEE EEEE +
Sbjct: 361 EDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQ 399
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/61 (45%), Positives = 40/61 (65%), Gaps = 1/61 (1%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
D +++++E EEE EEE EEEE E+EEEE EEEEEE EE ++ E+ +++ P
Sbjct: 360 DEDEEEEEEGEEE-EEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPN 418
Query: 72 T 72
T
Sbjct: 419 T 419
Score = 48.9 bits (115), Expect = 1e-05
Identities = 26/47 (55%), Positives = 33/47 (70%)
Query: 4 LRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEE 50
L S S D ++++ E EEE EEEEEE+ EEEEEE EEEEEE ++
Sbjct: 354 LASLSDDEDEEEEEEGEEEEEEAEEEEEEDEEEEEEEEEEEEEEPQQ 400
Score = 45.1 bits (105), Expect = 2e-04
Identities = 23/59 (38%), Positives = 38/59 (64%), Gaps = 1/59 (1%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
+ G+++++E+EEE EEE+EEEE EEEEEE EE ++ + E+ +++ AP
Sbjct: 367 EEGEEEEEEAEEE-EEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAP 424
Score = 40.0 bits (92), Expect = 0.007
Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 19/127 (14%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G+ G + +E E + + ++E+E EEEE E EEEEE EEE EE+E E
Sbjct: 334 GEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGE--EEEEEAEEEEEEDEEEEEEEE 391
Query: 71 ETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTETPSASPPSST 130
E EE P R + +PS + + S+ PP+
Sbjct: 392 EEEEEE---------------PQQRGQGEKSATPS--RKILDPNTGEPAPVLSSPPPADV 434
Query: 131 SSHKSFP 137
S+ +FP
Sbjct: 435 STFLAFP 441
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 60.5 bits (145), Expect = 5e-09
Identities = 62/220 (28%), Positives = 93/220 (42%), Gaps = 14/220 (6%)
Query: 3 HLRSPSGFGDPGKKDQKESEEELEEE-EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELV 61
H SG D + + EE +EE+ EE+EEVEE+ EE EE +E+ EEEEEE EEE
Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
Query: 62 GEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTET 121
EE+E EEY D + +D+ D R + S S++ T +S + T+
Sbjct: 243 EEEEE--------EEYEQDERDQKEEGNDY-DTRSEASDSGSESVSFTDGSVRSGSGTDG 293
Query: 122 PSASPPSSTSSHKSFPKIFQTFRKDMSE-MSIDRNIHRNLSPGIPVSVQTEESWLQDLSD 180
+ P +F SE + H LS + + + S L+ +
Sbjct: 294 SDEKKKERKRARGISPIVFDRSGSSASESYAGSEKKHEKLSSSVRAVRKDQTSKLKYVLQ 353
Query: 181 KVQSRKKASKEKAEPECLASKLREKWVINP-EESKLNILY 219
+R K +K + W P E KLN+ +
Sbjct: 354 --DARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAF 391
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 60.1 bits (144), Expect = 6e-09
Identities = 33/63 (52%), Positives = 45/63 (71%), Gaps = 5/63 (7%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEE-----VVEEELVGEEQELEA 69
+++ +E EEE+EEEE+EEE EE+EEE E+EEE+ E+EEEE +EEE V EE + E
Sbjct: 120 EEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEI 179
Query: 70 PET 72
T
Sbjct: 180 QRT 182
Score = 53.5 bits (127), Expect = 6e-07
Identities = 26/53 (49%), Positives = 41/53 (77%)
Query: 16 KDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
+++++ EE+ E+EEEEE+ EE+EE+ EEEE+E ++ EEE VEEE+ E Q +
Sbjct: 131 EEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTEIQRTQ 183
Score = 52.0 bits (123), Expect = 2e-06
Identities = 28/52 (53%), Positives = 36/52 (69%)
Query: 25 LEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
+EEEE EEE EE EEE +EEE+E +EEEEE EE+ EE+E + + EE
Sbjct: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEE 169
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/55 (54%), Positives = 38/55 (69%), Gaps = 3/55 (5%)
Query: 22 EEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
EEE EEEEEE EEE+EE +EE+EE EE+EEE E+E EE+E E + E+
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDE---EEEEKEGKKMEEEK 170
Score = 49.7 bits (117), Expect = 9e-06
Identities = 27/55 (49%), Positives = 37/55 (67%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
++ +++ L EEEE E EEEE E EE+EEE EE+EEE +EE E++E E E
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
Score = 47.8 bits (112), Expect = 3e-05
Identities = 27/51 (52%), Positives = 34/51 (66%)
Query: 26 EEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
EE ++ + EEEEVEEEEEEVEEEE+E +EE EE++ E E EE
Sbjct: 108 EECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE 158
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 60.1 bits (144), Expect = 6e-09
Identities = 49/153 (32%), Positives = 70/153 (45%), Gaps = 10/153 (6%)
Query: 3 HLRSPSGFGDPGKKDQKESEEELEEE-EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELV 61
H SG D + + EE +EE+ EE+EEVEE+ EE EE +E+ EEEEEE EEE
Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
Query: 62 GEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTET 121
EE+E EEY D + +D+ D R + S S++ T +S + T+
Sbjct: 243 EEEEE--------EEYEQDERDQKEEGNDY-DTRSEASDSGSESVSFTDGSVRSGSGTDG 293
Query: 122 PSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDR 154
+ P +F SE D+
Sbjct: 294 SDEKKKERKRARGISPIVFDRSGSSASESYADQ 326
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 57.8 bits (138), Expect = 3e-08
Identities = 31/57 (54%), Positives = 37/57 (64%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
+K ++E E + E+EEE EEEEEE EEEEEE EEEEEE V L E+E E E
Sbjct: 80 EKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEE 136
Score = 51.6 bits (122), Expect = 2e-06
Identities = 28/51 (54%), Positives = 34/51 (66%), Gaps = 8/51 (15%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEE--------EEEVEEEEEEVV 56
GK+ +KE E+E EEEEEEEE EEEEEE EEE E E E EE+ ++
Sbjct: 90 GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/56 (50%), Positives = 35/56 (62%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
+++ K E+E E+EEEEEE EEEEEE EEEEEE E E EE+ L +P
Sbjct: 87 RREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLISP 142
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/54 (46%), Positives = 35/54 (64%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
++++K EE+ EE+ EE E + E+EEE+ EEEEEE EEE EE+E E
Sbjct: 67 RREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEE 120
Score = 47.0 bits (110), Expect = 6e-05
Identities = 28/66 (42%), Positives = 38/66 (57%), Gaps = 2/66 (3%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEE--EEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G +K Q+ E+ EE+ EE+ EE+ E E+EE +EEEEE EEE EE+E E
Sbjct: 59 GTSARKSQRREEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEE 118
Query: 69 APETFS 74
+FS
Sbjct: 119 EEVSFS 124
Score = 45.8 bits (107), Expect = 1e-04
Identities = 24/51 (47%), Positives = 31/51 (60%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELV 61
G +K++++ EEE EEEEEEEE EEEEEE E E E E+ L+
Sbjct: 90 GKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 57.8 bits (138), Expect = 3e-08
Identities = 35/63 (55%), Positives = 40/63 (63%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73
G+ +++E E E EEEE EEE EEE E EE E E EEEEE VE E+ GEE E E E
Sbjct: 979 GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE 1038
Query: 74 SEE 76
EE
Sbjct: 1039 GEE 1041
Score = 52.0 bits (123), Expect = 2e-06
Identities = 35/65 (53%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVE-EEEEEVVEEELVGEEQELEAP 70
+ GK +++E EEE E EEEE E EEEE E EEEE E + EEE E E E GEE E E
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGE 879
Query: 71 ETFSE 75
E E
Sbjct: 880 EEEGE 884
Score = 50.8 bits (120), Expect = 4e-06
Identities = 31/65 (47%), Positives = 39/65 (60%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
GD G+ +++E+E EE+EE EVE E E + E E EEEE E EEE GEE+E E
Sbjct: 791 GDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGE 850
Query: 71 ETFSE 75
E E
Sbjct: 851 EEEGE 855
Score = 47.4 bits (111), Expect = 4e-05
Identities = 32/67 (47%), Positives = 37/67 (55%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G G+ + + + EEE EEE EEE EEE E E EEEE E E EV EE GE +E E
Sbjct: 979 GEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE 1038
Query: 69 APETFSE 75
E E
Sbjct: 1039 GEEEGEE 1045
Score = 47.0 bits (110), Expect = 6e-05
Identities = 34/71 (47%), Positives = 40/71 (56%), Gaps = 3/71 (4%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEE---EVEEEEEEVVEEELVGEEQ 65
G + G+ + ++ E E EEEE E E EEEE E E EEE E EE E E EEE GE +
Sbjct: 932 GEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGE 991
Query: 66 ELEAPETFSEE 76
E E E EE
Sbjct: 992 EEEGEEEGEEE 1002
Score = 47.0 bits (110), Expect = 6e-05
Identities = 33/66 (50%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEE---EVEEEEEEVEEEEEEVVEEELVGEEQ 65
G G+ G+ + +E E E E EEEE E E EEE E EE E E EEEE E EE GEE+
Sbjct: 939 GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Query: 66 ELEAPE 71
E E
Sbjct: 999 GEEEGE 1004
Score = 46.6 bits (109), Expect = 7e-05
Identities = 37/86 (43%), Positives = 47/86 (54%), Gaps = 6/86 (6%)
Query: 11 GDPGKKDQKESEEELEEEEE---EEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQEL 67
G+ + ++E E E EEEEE E EVE EE E E EEEE EEE EE E+E GEE
Sbjct: 999 GEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE-REKEGEGEENRR 1057
Query: 68 EAPETFSEEYLWKVTDIGDYDDDFPD 93
E EE K + G+ +++ D
Sbjct: 1058 NREEEEEEE--GKYQETGEEENERQD 1081
Score = 45.8 bits (107), Expect = 1e-04
Identities = 30/68 (44%), Positives = 38/68 (55%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G G+ ++++ E E E+E EE E E EEEE E E EE E E E EE EE+E +
Sbjct: 1009 GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGK 1068
Query: 69 APETFSEE 76
ET EE
Sbjct: 1069 YQETGEEE 1076
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/60 (51%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEV-EEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
QKE +E+EE EEE E EEEE EEEEE E E +E E E V E+E E E EE
Sbjct: 720 QKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEE 779
Score = 45.4 bits (106), Expect = 2e-04
Identities = 32/65 (49%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G+ G+ + +E E E E E+ E E EEEE E E EEEE E E EE E E GEE E E
Sbjct: 925 GEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE--GEEGEGEGE 982
Query: 71 ETFSE 75
E E
Sbjct: 983 EEEGE 987
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/60 (48%), Positives = 36/60 (60%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G + G+ +++E E + EEE EE E EEE EE E E EE E E E E E GEE+E E
Sbjct: 842 GEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/58 (51%), Positives = 33/58 (56%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSE 75
++E E E EE E E E EE E E EEEE E E EEE EEE GE +E E E E
Sbjct: 967 EEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE 1024
Score = 43.9 bits (102), Expect = 5e-04
Identities = 27/52 (51%), Positives = 32/52 (61%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQ 65
G++++ E E E E E E EE E E EE E E E EEE EE EEE GEE+
Sbjct: 957 GEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Score = 43.5 bits (101), Expect = 6e-04
Identities = 33/80 (41%), Positives = 39/80 (48%), Gaps = 17/80 (21%)
Query: 14 GKKDQKESEEELEEEEEEE-----------------EVEEEEEEVEEEEEEVEEEEEEVV 56
GK+++ E E + E EEEE EVEE + E EEEEEE E EEEE
Sbjct: 782 GKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGE 841
Query: 57 EEELVGEEQELEAPETFSEE 76
EE GE +E E EE
Sbjct: 842 GEEEEGEGEEEEGEGKGEEE 861
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/58 (51%), Positives = 36/58 (62%), Gaps = 3/58 (5%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEE---VVEEELVGEEQELE 68
G+++ +E E E EEEE E E E+ E E EEEE E E EEEE EEE GE +E E
Sbjct: 921 GEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE 978
Score = 43.1 bits (100), Expect = 8e-04
Identities = 27/58 (46%), Positives = 37/58 (63%), Gaps = 3/58 (5%)
Query: 14 GKKDQKESEEE---LEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G+++ E EEE EEEEE+E +EE E EE E E E+EE E +EE G+E++ E
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGE 788
Score = 43.1 bits (100), Expect = 8e-04
Identities = 31/59 (52%), Positives = 37/59 (62%), Gaps = 3/59 (5%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVE-EEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G+ G+ +++ E E E EEEE E E EEE E E EEEE E E EE E E GEE+E E
Sbjct: 862 GEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGE--GEEEEGE 918
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/68 (41%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE--ELVGEEQELE 68
GD ++++KE E + E E EE E E E+EE E ++EE +EE+ EE + GEE+E E
Sbjct: 743 GDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETE 802
Query: 69 APETFSEE 76
EE
Sbjct: 803 GRGEEKEE 810
Score = 42.7 bits (99), Expect = 0.001
Identities = 29/63 (46%), Positives = 35/63 (55%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73
G++++ E EEE E EEEE + EEE EE E E E EE E EE GE + E E
Sbjct: 835 GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGE 894
Query: 74 SEE 76
EE
Sbjct: 895 GEE 897
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/69 (49%), Positives = 38/69 (55%), Gaps = 6/69 (8%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVE---EEEEEVEEEEEE---VVEEELVGEEQEL 67
GK +++ E E EEE EE E E EEEE E EEE E E EEEE EEE GE +E
Sbjct: 856 GKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEE 915
Query: 68 EAPETFSEE 76
E EE
Sbjct: 916 EGEGKGEEE 924
Score = 42.7 bits (99), Expect = 0.001
Identities = 34/75 (45%), Positives = 41/75 (54%), Gaps = 4/75 (5%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEE---EEEVEEEEEEVVEEELVGEEQ 65
G G+ ++ + E EEE E E EEE E E EE E E EEE EE E E EEE GE +
Sbjct: 883 GEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE 942
Query: 66 ELEAPETFSEEYLWK 80
+ E E EE W+
Sbjct: 943 DGEG-EGEEEEGEWE 956
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/60 (45%), Positives = 38/60 (63%), Gaps = 3/60 (5%)
Query: 12 DPGKKDQKESEEELEEE---EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
D +++QKE E+ ++E E EE EEE E EEEE + EEEEE+ E + GE +E+E
Sbjct: 706 DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVE 765
Score = 42.4 bits (98), Expect = 0.001
Identities = 32/68 (47%), Positives = 38/68 (55%), Gaps = 1/68 (1%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G G+ + + +E E E EEEE E + EEE EE E EEE EE E E EEE GE +E
Sbjct: 833 GEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEE-GEGEEEGEEGEGEGEEEEGEGEGEEEG 891
Query: 69 APETFSEE 76
E EE
Sbjct: 892 EGEGEEEE 899
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/66 (46%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 14 GKKDQKESEEELEE---EEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G++++ E EEE E EEE EE E EEE E E E EEE E EEE GE +E E
Sbjct: 842 GEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901
Query: 71 ETFSEE 76
EE
Sbjct: 902 GEGEEE 907
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/60 (41%), Positives = 38/60 (63%), Gaps = 3/60 (5%)
Query: 9 GFGDPGKKDQKESEEELEEEEE---EEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQ 65
G + G+ +++E + E EEE+E +EE E EE E E E+EE E ++EE +E GEE+
Sbjct: 731 GEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE 790
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/66 (46%), Positives = 37/66 (56%), Gaps = 1/66 (1%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE-EQELEAP 70
+ G++ + E EEE E E EEE E E EE E E E EE E E EEE G+ E+E E
Sbjct: 869 EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEG 928
Query: 71 ETFSEE 76
E EE
Sbjct: 929 EGEGEE 934
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/68 (45%), Positives = 37/68 (54%), Gaps = 5/68 (7%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEE-----EEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G+ +++E E E EEE E E EEE EEE EE E E EEEE E E+ GE +E E
Sbjct: 893 GEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE 952
Query: 69 APETFSEE 76
EE
Sbjct: 953 GEWEGEEE 960
Score = 42.0 bits (97), Expect = 0.002
Identities = 32/69 (46%), Positives = 38/69 (55%), Gaps = 1/69 (1%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE-EQEL 67
G G+ ++ + E EEE E + EEE EE E E EEEE E E E+ E EE GE E E
Sbjct: 900 GEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE 959
Query: 68 EAPETFSEE 76
E E EE
Sbjct: 960 EEGEGEGEE 968
Score = 41.6 bits (96), Expect = 0.002
Identities = 32/58 (55%), Positives = 34/58 (58%), Gaps = 4/58 (6%)
Query: 14 GKKDQKESEEELEEEEEEEEV---EEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G+ + E EE E EEEEE EEEE E EEEE E EEEE E EE GEE E E
Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE-EGEEGEGE 868
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/68 (45%), Positives = 35/68 (51%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G + G+ +E EE E EEE EE E E EE E E E EE E E EEE GE +E
Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908
Query: 69 APETFSEE 76
E EE
Sbjct: 909 EGEGEEEE 916
Score = 41.6 bits (96), Expect = 0.002
Identities = 35/69 (50%), Positives = 39/69 (56%), Gaps = 5/69 (7%)
Query: 11 GDPGKKDQKESEEELE-EEEEEEEVEEEEEEVEEEEE---EVEEEEEEVVEEELVGEEQE 66
G+ G+ + +E E E E EEE E E EEEE E E EEE E EEEE E EE GEE E
Sbjct: 871 GEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE-EGEEGE 929
Query: 67 LEAPETFSE 75
E E E
Sbjct: 930 GEGEEEEGE 938
Score = 41.6 bits (96), Expect = 0.002
Identities = 27/56 (48%), Positives = 32/56 (57%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQE 66
G+ +++ E E E E E EEE E E E EE EEE EEE E E E GEE+E
Sbjct: 962 GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/68 (44%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEE----EEVVEEELVGEE 64
G G+ + D++E EE+ E +EE E EE E E E+EE E ++EE EE EEE G++
Sbjct: 736 GEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEE--GDQ 793
Query: 65 QELEAPET 72
E E ET
Sbjct: 794 GEGEEEET 801
Score = 41.2 bits (95), Expect = 0.003
Identities = 31/67 (46%), Positives = 37/67 (55%), Gaps = 4/67 (5%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEE----EVEEEEEEVVEEELVGEEQELEA 69
G+ +++E E + EEE EE E E EEEE E E E E EEEE E EE GE + E
Sbjct: 910 GEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEE 969
Query: 70 PETFSEE 76
E EE
Sbjct: 970 GEGEGEE 976
Score = 40.8 bits (94), Expect = 0.004
Identities = 26/62 (41%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73
G++ + E EEE E EEE EE E+E E E EEEEEE +E EE E + E +
Sbjct: 1027 GEEGEGEGEEE-EGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEY 1085
Query: 74 SE 75
+
Sbjct: 1086 KK 1087
Score = 40.4 bits (93), Expect = 0.005
Identities = 31/69 (44%), Positives = 36/69 (52%), Gaps = 6/69 (8%)
Query: 14 GKKDQKESEEELEEEE------EEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQEL 67
G+++ +E E E EEEE EE E E EEEE E E EE E E E E E GEE+
Sbjct: 867 GEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGE 926
Query: 68 EAPETFSEE 76
E EE
Sbjct: 927 EGEGEGEEE 935
Score = 39.3 bits (90), Expect = 0.012
Identities = 29/64 (45%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Query: 15 KKDQKESEEELEEEEEEEEVEE--EEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPET 72
K+ +E EE EEE E E EE EEE E+E E EE E E VE E EE E + E
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780
Query: 73 FSEE 76
+E
Sbjct: 781 AGKE 784
Score = 37.7 bits (86), Expect = 0.034
Identities = 21/64 (32%), Positives = 38/64 (59%)
Query: 13 PGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPET 72
PG+ +++ +E+E ++ + EE E++E E ++E +E EE EE GEE+E + E
Sbjct: 689 PGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
Query: 73 FSEE 76
+E
Sbjct: 749 EEKE 752
Score = 37.4 bits (85), Expect = 0.045
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 3/57 (5%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
K+D +E E++ E+ ++E +E EE EEE EEEE EEE EE+E E E
Sbjct: 704 KRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE---EEKEGEGKE 757
Score = 35.8 bits (81), Expect = 0.13
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 6/66 (9%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEE------EEVEEEEEEVEEEEEEVVEEELVGEEQ 65
+ G+KD+ E E E E+E E+EE EE E++E E ++E E E GEE+
Sbjct: 675 EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEE 734
Query: 66 ELEAPE 71
E E
Sbjct: 735 HGEGEE 740
Score = 35.8 bits (81), Expect = 0.13
Identities = 24/66 (36%), Positives = 37/66 (56%), Gaps = 3/66 (4%)
Query: 14 GKKDQKESEEELEE---EEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G+++++E E + EE +EE+ E E ++ E EEEE E EE+E E GE +E +
Sbjct: 766 GEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGE 825
Query: 71 ETFSEE 76
EE
Sbjct: 826 REEEEE 831
Score = 33.5 bits (75), Expect = 0.64
Identities = 21/63 (33%), Positives = 35/63 (55%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G G+ + ++++ E E ++EE + E+ EEE ++ E E EE E E+E GE + E
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Query: 69 APE 71
E
Sbjct: 819 VEE 821
Score = 32.0 bits (71), Expect = 1.9
Identities = 20/59 (33%), Positives = 34/59 (57%), Gaps = 11/59 (18%)
Query: 21 SEEELEEEEEEEEVEE------EEEEVEEEEEEVE-----EEEEEVVEEELVGEEQELE 68
S+EE+E EE+E E+ EE+EVE EE V+ +E+ E++ ++L + + E
Sbjct: 580 SDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSE 638
Score = 32.0 bits (71), Expect = 1.9
Identities = 17/48 (35%), Positives = 26/48 (54%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE 58
G+ +K+ + E EEEEEE + +E EEE E + EE + V +
Sbjct: 1043 GEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSK 1090
Score = 29.6 bits (65), Expect = 9.3
Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 14/98 (14%)
Query: 7 PSGFGDPGKKDQKESEEELEEEEEEE--------------EVEEEEEEVEEEEEEVEEEE 52
P G GD ++ E ++EE E+ E E+E E EE ++ EE+
Sbjct: 651 PEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQ 710
Query: 53 EEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDD 90
E+ E+ +E+ E E EE+ + GD +++
Sbjct: 711 EQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEE 748
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 57.4 bits (137), Expect = 4e-08
Identities = 31/73 (42%), Positives = 46/73 (63%), Gaps = 9/73 (12%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE---------EQ 65
++ +++ +++ ++EEEEEE EEEEEE EEEEEE EEEEEE+ + E E+
Sbjct: 1119 QQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEE 1178
Query: 66 ELEAPETFSEEYL 78
LE P+ S +L
Sbjct: 1179 VLEQPQPLSFGHL 1191
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/58 (46%), Positives = 42/58 (72%), Gaps = 6/58 (10%)
Query: 19 KESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
+ ++++ ++++++++ EEEEEE EEEEEE EEEEEE E EE+EL P+ FS E
Sbjct: 1116 RAAQQQKQQQQQQKQQEEEEEEEEEEEEEEEEEEEEAEE-----EEEEL-PPQYFSSE 1167
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 57.0 bits (136), Expect = 5e-08
Identities = 39/121 (32%), Positives = 66/121 (54%), Gaps = 5/121 (4%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
+PG +D+ E+E + EEEEE+EEE+E+ +E+ E+VE+EEEE EEE EE+E E +
Sbjct: 116 EPGDEDE---EDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEE--EEEEEEENED 170
Query: 72 TFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVPSQSATSTETPSASPPSSTS 131
+ ++ + DD+ D +V+ SL + ++ A + S+TS
Sbjct: 171 HQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTS 230
Query: 132 S 132
+
Sbjct: 231 N 231
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/71 (42%), Positives = 39/71 (54%), Gaps = 9/71 (12%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE--------ELVGEEQ 65
G +D E EE+ E EE E+ +E +E EE+EE EEEEE+ EE E V +E+
Sbjct: 95 GTEDMDEKEED-EGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEE 153
Query: 66 ELEAPETFSEE 76
E E E EE
Sbjct: 154 EEEEEEEEEEE 164
Score = 36.6 bits (83), Expect = 0.076
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 14/75 (18%)
Query: 16 KDQKESEEELEEEEEEEEVEEEEE--------------EVEEEEEEVEEEEEEVVEEELV 61
K S +E ++ + E+++E+EE + +EE+EE + EEEE +EEE
Sbjct: 81 KADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDE 140
Query: 62 GEEQELEAPETFSEE 76
++++ E E EE
Sbjct: 141 DDDEDGEDVEDEEEE 155
>gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo
sapiens]
Length = 1925
Score = 57.0 bits (136), Expect = 5e-08
Identities = 32/56 (57%), Positives = 39/56 (69%), Gaps = 3/56 (5%)
Query: 7 PSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEE---EEVEEEEEEVVEEE 59
P + GKK++ E E+ EEEEE EE EEEEEE EEEE EE+EE+EEE E+E
Sbjct: 1751 PEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKE 1806
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/55 (54%), Positives = 38/55 (69%)
Query: 13 PGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQEL 67
PG ++E EEE EEEEEE EEEEEE E EEEE+ +EE E EEE +E+++
Sbjct: 1755 PGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKV 1809
Score = 52.0 bits (123), Expect = 2e-06
Identities = 25/51 (49%), Positives = 38/51 (74%)
Query: 5 RSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEV 55
+ G + G+++++E EEE EEEEE EE E +EE+EE+EEE +E+EE+V
Sbjct: 1759 KKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKV 1809
Score = 51.2 bits (121), Expect = 3e-06
Identities = 31/76 (40%), Positives = 48/76 (63%), Gaps = 6/76 (7%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEEL----VGEE 64
G + G++++ E EEE EEEEEEE E EEEE+ +EE E +EEE + EE++ +G
Sbjct: 1758 GKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKEEIEEKEEERDEKEEKVSWAGIGPT 1817
Query: 65 QELEAPETFSEEYLWK 80
+ E+ E S ++ W+
Sbjct: 1818 PQPESQE--SMQWQWQ 1831
Score = 49.3 bits (116), Expect = 1e-05
Identities = 32/72 (44%), Positives = 44/72 (61%), Gaps = 1/72 (1%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73
GK+ +++ E ++EE EEE+ E EEEE E EEEEEE EEE +G+E E+E E
Sbjct: 1743 GKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETEEEELGKE-EIEEKEEE 1801
Query: 74 SEEYLWKVTDIG 85
+E KV+ G
Sbjct: 1802 RDEKEEKVSWAG 1813
Score = 48.1 bits (113), Expect = 3e-05
Identities = 33/68 (48%), Positives = 40/68 (58%), Gaps = 2/68 (2%)
Query: 9 GFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
G G K+D+ E L ++EE EE + EEEE E EEEE EEEE E EEEL EE E +
Sbjct: 1741 GKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEEEEEEEEETE--EEELGKEEIEEK 1798
Query: 69 APETFSEE 76
E +E
Sbjct: 1799 EEERDEKE 1806
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 56.6 bits (135), Expect = 7e-08
Identities = 31/50 (62%), Positives = 35/50 (70%), Gaps = 3/50 (6%)
Query: 22 EEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
EEE E EEE+EE++EE E EEEEEE EEEEEE EEE EEQ P+
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEE---EEQPRAGPQ 154
Score = 53.1 bits (126), Expect = 8e-07
Identities = 30/59 (50%), Positives = 38/59 (64%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
++E+E E E+EE +EE EEEEE EEEEEE EEEEEE E+ G + E +S E
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLE 166
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/62 (46%), Positives = 39/62 (62%), Gaps = 3/62 (4%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVG---EEQELEAPETF 73
+++E +EE++EE EEE EEEEEE EEEEEE EEEE+ + G E+ LE +
Sbjct: 112 EREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQAL 171
Query: 74 SE 75
E
Sbjct: 172 EE 173
Score = 50.1 bits (118), Expect = 7e-06
Identities = 25/41 (60%), Positives = 31/41 (75%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEE 54
G+++ + EE+ E +EE E EEEEEE EEEEEE EEEEEE
Sbjct: 107 GEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEE 147
Score = 43.1 bits (100), Expect = 8e-04
Identities = 25/60 (41%), Positives = 33/60 (55%), Gaps = 7/60 (11%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEE-------EEEEVEEEEEEVVEEELVGEEQELEAP 70
++E EEE EEEEEEEE EEEEE+ E+ EE++ +EE + E L P
Sbjct: 126 EEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSSETSALPRP 185
Score = 40.8 bits (94), Expect = 0.004
Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 15/75 (20%)
Query: 17 DQKESEEELEEEEEEEE---------------VEEEEEEVEEEEEEVEEEEEEVVEEELV 61
DQ+ + E++E E E+ V EEE E EEE+EE++EE E EEE
Sbjct: 74 DQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGEEEEEEEE 133
Query: 62 GEEQELEAPETFSEE 76
EE+E E E E+
Sbjct: 134 EEEEEEEEEEEEEEQ 148
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 56.6 bits (135), Expect = 7e-08
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 26/181 (14%)
Query: 7 PSGFGDPG-------KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEV-------EEEE 52
PSG G + D ++ EE EEEEEEEE EEEE EEEE++ E++E
Sbjct: 419 PSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478
Query: 53 EEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVP 112
EE EEE + ++P + + K + G + IVSPSL S
Sbjct: 479 EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPL 538
Query: 113 SQSATSTETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEE 172
+ S+ E+ P T +S + Q F ++ + +D P SV+T+
Sbjct: 539 APSSIDAESNGEQPEELTLEEES--PVSQLFELEIEALPLD----------TPSSVETDI 586
Query: 173 S 173
S
Sbjct: 587 S 587
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 56.6 bits (135), Expect = 7e-08
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 26/181 (14%)
Query: 7 PSGFGDPG-------KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEV-------EEEE 52
PSG G + D ++ EE EEEEEEEE EEEE EEEE++ E++E
Sbjct: 419 PSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 478
Query: 53 EEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVP 112
EE EEE + ++P + + K + G + IVSPSL S
Sbjct: 479 EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPL 538
Query: 113 SQSATSTETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEE 172
+ S+ E+ P T +S + Q F ++ + +D P SV+T+
Sbjct: 539 APSSIDAESNGEQPEELTLEEES--PVSQLFELEIEALPLD----------TPSSVETDI 586
Query: 173 S 173
S
Sbjct: 587 S 587
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 56.6 bits (135), Expect = 7e-08
Identities = 53/181 (29%), Positives = 78/181 (43%), Gaps = 26/181 (14%)
Query: 7 PSGFGDPG-------KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEV-------EEEE 52
PSG G + D ++ EE EEEEEEEE EEEE EEEE++ E++E
Sbjct: 431 PSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDE 490
Query: 53 EEVVEEELVGEEQELEAPETFSEEYLWKVTDIGDYDDDFPDVRPRLASIVSPSLTSTFVP 112
EE EEE + ++P + + K + G + IVSPSL S
Sbjct: 491 EEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPL 550
Query: 113 SQSATSTETPSASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEE 172
+ S+ E+ P T +S + Q F ++ + +D P SV+T+
Sbjct: 551 APSSIDAESNGEQPEELTLEEES--PVSQLFELEIEALPLD----------TPSSVETDI 598
Query: 173 S 173
S
Sbjct: 599 S 599
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 55.8 bits (133), Expect = 1e-07
Identities = 27/57 (47%), Positives = 41/57 (71%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
+ +K+++E ++E+EE +EE+E E+ + + EEEEEE E EEEEV E E GEE + E
Sbjct: 1018 EDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTE 1074
Score = 53.1 bits (126), Expect = 8e-07
Identities = 36/77 (46%), Positives = 48/77 (62%), Gaps = 9/77 (11%)
Query: 6 SPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEE-------EVEEEEEEVVEE 58
SPS GD +++ EE+ + E+EEEE ++E EE++EE+E E EEEEEE VEE
Sbjct: 1000 SPSQ-GDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEE 1058
Query: 59 ELVGEEQELEAPETFSE 75
E V EE E E E +E
Sbjct: 1059 EEV-EEAENEGEEAKTE 1074
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/69 (43%), Positives = 41/69 (59%), Gaps = 8/69 (11%)
Query: 16 KDQKESEE-ELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQEL------- 67
+++KE E+ + +EEEEEEE E EEEEVEE E E EE + E + ++ E Q
Sbjct: 1035 QEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVG 1094
Query: 68 EAPETFSEE 76
E+ E SEE
Sbjct: 1095 ESSEQVSEE 1103
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G Q +S+E EE+E E+EE EEE++E+EE +EE E+ G+E+E E
Sbjct: 996 GARASPSQGDSDERESLTREEDEDSEKEE--EEEDKEMEELQEEKECEKPQGDEEEEEEE 1053
Query: 71 ETFSEEYLWKVTDIGD 86
E EE + + + G+
Sbjct: 1054 EEVEEEEVEEAENEGE 1069
Score = 36.2 bits (82), Expect = 0.099
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Query: 1 MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE-- 58
M L+ P +++E EEE EEEE EE E E EE + E ++ E
Sbjct: 1031 MEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLG 1090
Query: 59 ELVGEEQELEAPETFSE 75
+ VGE E + E +E
Sbjct: 1091 QKVGESSEQVSEEKTNE 1107
Score = 30.8 bits (68), Expect = 4.2
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 18/79 (22%)
Query: 16 KDQKESEEELEEEEEEEEV---------------EEEEEEVEEEEEEVE---EEEEEVVE 57
K + E + E+EE E+ + +E E EE+ + EEEEE E
Sbjct: 971 KREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKE 1030
Query: 58 EELVGEEQELEAPETFSEE 76
E + EE+E E P+ EE
Sbjct: 1031 MEELQEEKECEKPQGDEEE 1049
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 55.8 bits (133), Expect = 1e-07
Identities = 27/57 (47%), Positives = 41/57 (71%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68
+ +K+++E ++E+EE +EE+E E+ + + EEEEEE E EEEEV E E GEE + E
Sbjct: 1034 EDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTE 1090
Score = 53.1 bits (126), Expect = 8e-07
Identities = 36/77 (46%), Positives = 48/77 (62%), Gaps = 9/77 (11%)
Query: 6 SPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEE-------EVEEEEEEVVEE 58
SPS GD +++ EE+ + E+EEEE ++E EE++EE+E E EEEEEE VEE
Sbjct: 1016 SPSQ-GDSDERESLTREEDEDSEKEEEEEDKEMEELQEEKECEKPQGDEEEEEEEEEVEE 1074
Query: 59 ELVGEEQELEAPETFSE 75
E V EE E E E +E
Sbjct: 1075 EEV-EEAENEGEEAKTE 1090
Score = 43.5 bits (101), Expect = 6e-04
Identities = 30/69 (43%), Positives = 41/69 (59%), Gaps = 8/69 (11%)
Query: 16 KDQKESEE-ELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQEL------- 67
+++KE E+ + +EEEEEEE E EEEEVEE E E EE + E + ++ E Q
Sbjct: 1051 QEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLGQKVG 1110
Query: 68 EAPETFSEE 76
E+ E SEE
Sbjct: 1111 ESSEQVSEE 1119
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/76 (35%), Positives = 42/76 (55%), Gaps = 2/76 (2%)
Query: 11 GDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G Q +S+E EE+E E+EE EEE++E+EE +EE E+ G+E+E E
Sbjct: 1012 GARASPSQGDSDERESLTREEDEDSEKEE--EEEDKEMEELQEEKECEKPQGDEEEEEEE 1069
Query: 71 ETFSEEYLWKVTDIGD 86
E EE + + + G+
Sbjct: 1070 EEVEEEEVEEAENEGE 1085
Score = 36.2 bits (82), Expect = 0.099
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Query: 1 MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE-- 58
M L+ P +++E EEE EEEE EE E E EE + E ++ E
Sbjct: 1047 MEELQEEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLG 1106
Query: 59 ELVGEEQELEAPETFSE 75
+ VGE E + E +E
Sbjct: 1107 QKVGESSEQVSEEKTNE 1123
Score = 30.8 bits (68), Expect = 4.2
Identities = 24/79 (30%), Positives = 35/79 (44%), Gaps = 18/79 (22%)
Query: 16 KDQKESEEELEEEEEEEEV---------------EEEEEEVEEEEEEVE---EEEEEVVE 57
K + E + E+EE E+ + +E E EE+ + EEEEE E
Sbjct: 987 KREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREEDEDSEKEEEEEDKE 1046
Query: 58 EELVGEEQELEAPETFSEE 76
E + EE+E E P+ EE
Sbjct: 1047 MEELQEEKECEKPQGDEEE 1065
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/65 (44%), Positives = 40/65 (61%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
K + + E+L EEEEEEE EEEEEE EEEEEE EE+EE + + G +A + +
Sbjct: 288 KSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWR 347
Query: 75 EEYLW 79
++ W
Sbjct: 348 KDSPW 352
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/43 (62%), Positives = 30/43 (69%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEE 54
D K + E+ E EEEEEE EEEEEE EEEEEE EEE+EE
Sbjct: 284 DSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/47 (53%), Positives = 32/47 (68%)
Query: 20 ESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQE 66
+S+ E+E E+ EEEEEE EEEEEE EEEEEE E+E G + +
Sbjct: 286 DSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSD 332
Score = 47.4 bits (111), Expect = 4e-05
Identities = 24/43 (55%), Positives = 31/43 (72%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
++ +S+ + E E E++ EEEEE EEEEEE EEEEEE EEE
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEE 323
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 14/72 (19%)
Query: 11 GDPGKKDQKE--------------SEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVV 56
GDPG ++ E S +E + + + EVE E++ EEEEE EEEEEE
Sbjct: 254 GDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEE 313
Query: 57 EEELVGEEQELE 68
EEE EE+E E
Sbjct: 314 EEEEEEEEEEDE 325
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/65 (44%), Positives = 40/65 (61%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
K + + E+L EEEEEEE EEEEEE EEEEEE EE+EE + + G +A + +
Sbjct: 288 KSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWR 347
Query: 75 EEYLW 79
++ W
Sbjct: 348 KDSPW 352
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/43 (62%), Positives = 30/43 (69%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEE 54
D K + E+ E EEEEEE EEEEEE EEEEEE EEE+EE
Sbjct: 284 DSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEE 326
Score = 48.5 bits (114), Expect = 2e-05
Identities = 25/47 (53%), Positives = 32/47 (68%)
Query: 20 ESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQE 66
+S+ E+E E+ EEEEEE EEEEEE EEEEEE E+E G + +
Sbjct: 286 DSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSD 332
Score = 47.4 bits (111), Expect = 4e-05
Identities = 24/43 (55%), Positives = 31/43 (72%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
++ +S+ + E E E++ EEEEE EEEEEE EEEEEE EEE
Sbjct: 281 ERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEE 323
Score = 45.4 bits (106), Expect = 2e-04
Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 14/72 (19%)
Query: 11 GDPGKKDQKE--------------SEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVV 56
GDPG ++ E S +E + + + EVE E++ EEEEE EEEEEE
Sbjct: 254 GDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEE 313
Query: 57 EEELVGEEQELE 68
EEE EE+E E
Sbjct: 314 EEEEEEEEEEDE 325
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 55.1 bits (131), Expect = 2e-07
Identities = 27/62 (43%), Positives = 44/62 (70%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
+++++E EEE EEEE EE EE +EE E EE++VE+EEEE +++ +++E++ E
Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306
Query: 75 EE 76
EE
Sbjct: 2307 EE 2308
Score = 52.0 bits (123), Expect = 2e-06
Identities = 31/55 (56%), Positives = 36/55 (65%), Gaps = 5/55 (9%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPE 71
D+ E +E L EEEEE EEE E EEEEV EEEEE EEE GEE+++E E
Sbjct: 2235 DELEKQESLSSEEEEER----EEEEEREEEEVREEEEERKEEE-EGEEKQVEKEE 2284
Score = 51.6 bits (122), Expect = 2e-06
Identities = 31/62 (50%), Positives = 39/62 (62%), Gaps = 2/62 (3%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
K++ SEEE E EEEEE EEE E EEE +E EE EE+ VE+E EE++ + E
Sbjct: 2239 KQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKE--EEEKKKKKKEKKK 2296
Query: 75 EE 76
EE
Sbjct: 2297 EE 2298
Score = 51.2 bits (121), Expect = 3e-06
Identities = 29/69 (42%), Positives = 48/69 (69%), Gaps = 4/69 (5%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
+++ +E EEE +EEEE EE + E+EE E+++++ E+++EEV E+E V EE+E E S
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKE----EIMS 2314
Query: 75 EEYLWKVTD 83
EE ++D
Sbjct: 2315 EEETESLSD 2323
Score = 50.8 bits (120), Expect = 4e-06
Identities = 29/63 (46%), Positives = 42/63 (66%), Gaps = 1/63 (1%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEY 77
++E E E EEE EEEEV EEEEE +EEEE EE++ E EEE +++E + E +E
Sbjct: 2246 EEEEEREEEEEREEEEVREEEEE-RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEE 2304
Query: 78 LWK 80
+++
Sbjct: 2305 VFE 2307
Score = 48.5 bits (114), Expect = 2e-05
Identities = 29/72 (40%), Positives = 43/72 (59%), Gaps = 10/72 (13%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEE----------EEVEEEEEEVVEEELVGEE 64
+++++E EE EE +EEEE EE++ E EEEE EEV+E+EE E+E + E
Sbjct: 2256 EREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSE 2315
Query: 65 QELEAPETFSEE 76
+E E+ EE
Sbjct: 2316 EETESLSDEEEE 2327
Score = 47.8 bits (112), Expect = 3e-05
Identities = 28/66 (42%), Positives = 43/66 (65%), Gaps = 4/66 (6%)
Query: 15 KKDQKESEEELEEEEEEEEV----EEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
+K+++E EE+ E+EEEE+ E+++EEV+E+EE EE+EE + EEE E E
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEE 2328
Query: 71 ETFSEE 76
E+ S E
Sbjct: 2329 ESCSLE 2334
Score = 45.8 bits (107), Expect = 1e-04
Identities = 27/65 (41%), Positives = 42/65 (64%), Gaps = 6/65 (9%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEE------EVEEEEEEVVEEELVGEEQELE 68
+K +K+ E++ EE +E+EEV EE+EE+ EEE E EEEE +EEE+ E++ L+
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILK 2345
Query: 69 APETF 73
+ F
Sbjct: 2346 KEKQF 2350
Score = 41.2 bits (95), Expect = 0.003
Identities = 27/67 (40%), Positives = 36/67 (53%), Gaps = 1/67 (1%)
Query: 11 GDPGKKDQKESEEELEEEEE-EEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEA 69
GD K+ +E+E EE EE+E +E+E++E EEEEE EEE EE+ E
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREE 2265
Query: 70 PETFSEE 76
E EE
Sbjct: 2266 EEERKEE 2272
Score = 37.7 bits (86), Expect = 0.034
Identities = 25/65 (38%), Positives = 41/65 (63%), Gaps = 3/65 (4%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE-ELVGEEQELEA--PE 71
+++Q +E E +E EE+E + EE+ +EEE+ +EE ++VEE + + EE+E A E
Sbjct: 1702 QREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQRE 1761
Query: 72 TFSEE 76
SEE
Sbjct: 1762 KLSEE 1766
Score = 36.6 bits (83), Expect = 0.076
Identities = 19/52 (36%), Positives = 38/52 (73%), Gaps = 1/52 (1%)
Query: 16 KDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVV-EEELVGEEQE 66
K+++ ++EE + EE++++ EEEE + + E++ EEE ++ EEEL+ +E+E
Sbjct: 1731 KEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKE 1782
Score = 36.6 bits (83), Expect = 0.076
Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 2/73 (2%)
Query: 14 GKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETF 73
G K +++ +++E E EE EE E + +E E+ E E EEE EE+E E E
Sbjct: 2206 GDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSE--EEEEREEEEEREEEEVR 2263
Query: 74 SEEYLWKVTDIGD 86
EE K + G+
Sbjct: 2264 EEEEERKEEEEGE 2276
Score = 36.2 bits (82), Expect = 0.099
Identities = 17/41 (41%), Positives = 29/41 (70%)
Query: 19 KESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
+E E L +EEEEEE EEEV+ E+E +++E++ ++E+
Sbjct: 2315 EEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQ 2355
Score = 35.8 bits (81), Expect = 0.13
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 12/74 (16%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEE------------EEEVEEEEEEVVEEELVG 62
K+ K E+ + +E E E EE+E EEE E EEEE EEE V
Sbjct: 2204 KRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVR 2263
Query: 63 EEQELEAPETFSEE 76
EE+E E EE
Sbjct: 2264 EEEEERKEEEEGEE 2277
Score = 35.4 bits (80), Expect = 0.17
Identities = 26/90 (28%), Positives = 48/90 (53%), Gaps = 8/90 (8%)
Query: 15 KKDQKESEEELEEEEE-----EEEVEEEEEEVEEEEEEVEEEEEEVV-EEELVGEEQELE 68
+K+ + EELE + E EEE+ +EE ++ EE++++ EEEE + + E + EE+
Sbjct: 1711 EKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKL 1770
Query: 69 APETFSEEYLWKVTDIGDYDDDFPDVRPRL 98
A E E + + + + + P+ RL
Sbjct: 1771 AQE--EELLIQEKEKLAQHKEKMPEEEERL 1798
Score = 35.4 bits (80), Expect = 0.17
Identities = 46/169 (27%), Positives = 67/169 (39%), Gaps = 10/169 (5%)
Query: 19 KESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYL 78
+E EE + EEE E +EEEEE EE + E+E++++E + QE E
Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE-- 2364
Query: 79 WKVTDIGDYDDDFPDVRPRLASIVSP--SLTSTFVPSQSATSTETPSASPPSSTSSHKSF 136
+V I RL + SP L ST + + +TP P S
Sbjct: 2365 -RVLSILRGVPHGKGRAIRLGVLKSPLKKLMSTALEMKE----KTPVPVPEKQISWEDKK 2419
Query: 137 PKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTE-ESWLQDLSDKVQS 184
+ + RK + M +R + P P + T ES QDL S
Sbjct: 2420 ATVVEIPRKFLGTMDKEREVMGKYEPIPPHVLGTVLESQAQDLKTPFMS 2468
Score = 35.0 bits (79), Expect = 0.22
Identities = 16/40 (40%), Positives = 25/40 (62%)
Query: 19 KESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE 58
K E++ ++EEE EE E EE+E++V EE+ + EE
Sbjct: 1532 KSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEE 1571
Score = 35.0 bits (79), Expect = 0.22
Identities = 17/40 (42%), Positives = 27/40 (67%), Gaps = 1/40 (2%)
Query: 15 KKDQKESEEELE-EEEEEEEVEEEEEEVEEEEEEVEEEEE 53
K+ Q + EEE+ EEE E EE+E++V EE+ ++EE +
Sbjct: 1534 KEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHK 1573
Score = 35.0 bits (79), Expect = 0.22
Identities = 18/52 (34%), Positives = 36/52 (69%), Gaps = 2/52 (3%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEV--VEEELVGEEQEL 67
+K SEEE + +EEE + +E+E++ + +E++ EEEE + E+L+ ++ +L
Sbjct: 1761 EKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKL 1812
Score = 33.5 bits (75), Expect = 0.64
Identities = 27/86 (31%), Positives = 46/86 (53%), Gaps = 19/86 (22%)
Query: 16 KDQKES--EEEL--EEEEEEEEVEEEEEEVEEE-------------EEEVEEEEEEVVEE 58
KD++E EEE+ E EE+E++V EE+ ++EE E++ +EE ++ +E
Sbjct: 1539 KDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQE 1598
Query: 59 E--LVGEEQELEAPETFSEEYLWKVT 82
E L EE++L E + K+T
Sbjct: 1599 EEKLAQEERQLAQEERKLAQAYVKIT 1624
Score = 33.5 bits (75), Expect = 0.64
Identities = 22/56 (39%), Positives = 36/56 (64%), Gaps = 7/56 (12%)
Query: 23 EELEEEEE-----EEEVEEEEEEVEEEEEEVEEEEEEVVEEE--LVGEEQELEAPE 71
EEL + E+ E+E+ +E EE+E + EE+ +EEE+ +EE LV E+++L E
Sbjct: 1698 EELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEE 1753
Score = 33.1 bits (74), Expect = 0.84
Identities = 23/68 (33%), Positives = 38/68 (55%), Gaps = 10/68 (14%)
Query: 22 EEELEEE-----EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEEL--VGEEQELEAPET-- 72
EE L+E+ EE ++V E + +E++ ++EEE +EEE+ GEE+E + E
Sbjct: 1507 EEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQR 1566
Query: 73 -FSEEYLW 79
EE+ W
Sbjct: 1567 HIQEEHKW 1574
Score = 32.7 bits (73), Expect = 1.1
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 15 KKDQKESEEELE------EEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQE 66
KK E EE L EEE + +EEE ++E+E+ + +E+ EEE +G ++E
Sbjct: 1746 KKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKRE 1803
Score = 32.0 bits (71), Expect = 1.9
Identities = 13/56 (23%), Positives = 35/56 (62%), Gaps = 2/56 (3%)
Query: 18 QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEE--ELVGEEQELEAPE 71
+K + E + +EE ++ +EEE++ +EE ++ +EE ++ + ++ +++E+ E
Sbjct: 1579 RKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAE 1634
Score = 32.0 bits (71), Expect = 1.9
Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 19/75 (25%)
Query: 21 SEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVV-------------------EEELV 61
++EE EEE + + E + ++EEE EEEEV+ +E+
Sbjct: 2155 NKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFS 2214
Query: 62 GEEQELEAPETFSEE 76
+ E+E+ E FSEE
Sbjct: 2215 SQVDEVESEEHFSEE 2229
Score = 31.6 bits (70), Expect = 2.5
Identities = 20/68 (29%), Positives = 38/68 (55%), Gaps = 2/68 (2%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEV--VEEELVGEEQELEAPET 72
K QK ++ + ++E +V + + E+ +EE ++ EE EE+ +EE++V +E +L E
Sbjct: 1394 KTFQKSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIER 1453
Query: 73 FSEEYLWK 80
WK
Sbjct: 1454 TPSWQDWK 1461
Score = 31.2 bits (69), Expect = 3.2
Identities = 16/58 (27%), Positives = 34/58 (58%), Gaps = 13/58 (22%)
Query: 15 KKDQKESEEELEEEEE-------------EEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
+K+Q+ +EE+ +EE E++ +EE ++ +EEE++ +EE ++ +EE
Sbjct: 1556 EKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEE 1613
Score = 31.2 bits (69), Expect = 3.2
Identities = 10/45 (22%), Positives = 31/45 (68%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEE 59
+ ++K ++EE + +EEE++ +EE ++ +EE ++ + ++ +++
Sbjct: 1583 RAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDD 1627
Score = 30.8 bits (68), Expect = 4.2
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 5/87 (5%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEV--VEEELVGEEQELEAPET 72
KK +K + EE + ++ ++ E + + ++ EE+ + E+ + E+EL QELE E
Sbjct: 1667 KKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELA---QELEELEW 1723
Query: 73 FSEEYLWKVTDIGDYDDDFPDVRPRLA 99
EE WK ++ + + + +LA
Sbjct: 1724 DMEELSWKEEELNQEEGKLVEEKKKLA 1750
Score = 30.4 bits (67), Expect = 5.5
Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 2/62 (3%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFS 74
+K+ K ++ E+ + + E EE EE E + +E E+ +E L EE+E E
Sbjct: 2200 RKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEK--QESLSSEEEEEREEEEER 2257
Query: 75 EE 76
EE
Sbjct: 2258 EE 2259
Score = 29.6 bits (65), Expect = 9.3
Identities = 16/52 (30%), Positives = 31/52 (59%)
Query: 5 RSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVV 56
+SP +K++K + + E +EE ++ EE EE+ EE+V ++E ++V
Sbjct: 1398 KSPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLV 1449
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 54.7 bits (130), Expect = 3e-07
Identities = 35/90 (38%), Positives = 47/90 (52%), Gaps = 3/90 (3%)
Query: 17 DQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEE 76
D +E EE EEEE+EE EEEE+ E+E+E EE EE E E EE E E EE
Sbjct: 3 DIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDE---EE 59
Query: 77 YLWKVTDIGDYDDDFPDVRPRLASIVSPSL 106
K + G ++ P R + ++V P +
Sbjct: 60 EEAKEAEDGPMEESKPKPRSFMPNLVPPKI 89
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/61 (40%), Positives = 37/61 (60%)
Query: 16 KDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSE 75
+++++ E +EEEE+ E E+E+EE EE+ E E E EE EE EE+ EA + E
Sbjct: 12 EEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPME 71
Query: 76 E 76
E
Sbjct: 72 E 72
Score = 40.4 bits (93), Expect = 0.005
Identities = 21/45 (46%), Positives = 29/45 (64%), Gaps = 1/45 (2%)
Query: 15 KKDQKESEEELEEE-EEEEEVEEEEEEVEEEEEEVEEEEEEVVEE 58
++D+ E EE EE+ E E E EE E +EEEEE +E E+ +EE
Sbjct: 28 REDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE 72
Score = 37.7 bits (86), Expect = 0.034
Identities = 23/54 (42%), Positives = 32/54 (59%), Gaps = 2/54 (3%)
Query: 15 KKDQKESEEELEEE--EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQE 66
+++Q+E+ E EE+ E+E+E EE EE E E E EE E EEE +E E
Sbjct: 13 EEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAE 66
Score = 31.6 bits (70), Expect = 2.5
Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 10 FGDPGKKDQKESEEELEE--EEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQEL 67
F D +K ++ EL+ E E ++EEEE+ ++ +E E E++ + E+E
Sbjct: 97 FDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK 156
Query: 68 EAPETFSEE 76
E +EE
Sbjct: 157 ERQNRLAEE 165
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 54.7 bits (130), Expect = 3e-07
Identities = 33/68 (48%), Positives = 44/68 (64%), Gaps = 3/68 (4%)
Query: 14 GKKDQKESEEELEEE---EEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAP 70
G +D K+ + +E E EEEEE +EEEE EE+EEE EE+EEE +E+ E++E EA
Sbjct: 1855 GDEDVKQILKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAA 1914
Query: 71 ETFSEEYL 78
E EE L
Sbjct: 1915 EGEKEEGL 1922
Score = 50.8 bits (120), Expect = 4e-06
Identities = 25/61 (40%), Positives = 44/61 (72%), Gaps = 3/61 (4%)
Query: 15 KKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQ---ELEAPE 71
++++++ EEE EEE+EEE+ E+EEE +E+E+E +EEEE E+ G E+ +++ PE
Sbjct: 1874 EEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPE 1933
Query: 72 T 72
+
Sbjct: 1934 S 1934
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/55 (47%), Positives = 38/55 (69%), Gaps = 1/55 (1%)
Query: 12 DPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQE 66
+P ++E EE+ EEE EEE+ EE+EE+ EE +E E+EE+E EE GE++E
Sbjct: 1867 EPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKE-EEEAAEGEKEE 1920
Score = 30.4 bits (67), Expect = 5.5
Identities = 25/77 (32%), Positives = 44/77 (57%), Gaps = 10/77 (12%)
Query: 15 KKDQKESEEELEEEE-EEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGE-----EQEL- 67
++D++E+ +E E+EE EEEE E E+E EE ++ + E V+ ++ +QEL
Sbjct: 1893 EEDEEETAQEKEDEEKEEEEAAEGEKEEGLEEGLLQMKLPESVKLQMCHLLEYFCDQELQ 1952
Query: 68 ---EAPETFSEEYLWKV 81
E+ F+E Y+ K+
Sbjct: 1953 HRVESLAAFAERYVDKL 1969
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,841,306
Number of Sequences: 37866
Number of extensions: 1489821
Number of successful extensions: 75060
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1149
Number of HSP's successfully gapped in prelim test: 480
Number of HSP's that attempted gapping in prelim test: 19975
Number of HSP's gapped (non-prelim): 23786
length of query: 663
length of database: 18,247,518
effective HSP length: 109
effective length of query: 554
effective length of database: 14,120,124
effective search space: 7822548696
effective search space used: 7822548696
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.