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Search of human proteins with 86991438
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|86991438 splicing factor, arginine/serine-rich 5 [Homo
sapiens]
(272 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 531 e-151
gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 531 e-151
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 307 7e-84
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 297 6e-81
gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Ho... 168 4e-42
gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2 [... 133 2e-31
gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens] 122 3e-28
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 112 3e-25
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 94 1e-19
gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 92 5e-19
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 89 4e-18
gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens] 86 3e-17
gi|148612890 serine-arginine repressor protein [Homo sapiens] 85 6e-17
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 80 2e-15
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 79 4e-15
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 76 3e-14
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 76 3e-14
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 76 4e-14
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 76 4e-14
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 75 8e-14
gi|50962882 G patch domain containing 8 [Homo sapiens] 74 1e-13
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 74 1e-13
gi|187960109 RNA binding motif protein 28 [Homo sapiens] 71 1e-12
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 70 3e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 69 3e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 69 3e-12
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 69 4e-12
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 68 7e-12
gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 67 1e-11
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens] 67 2e-11
>gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 531 bits (1367), Expect = e-151
Identities = 272/272 (100%), Positives = 272/272 (100%)
Query: 1 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 60
MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
Sbjct: 1 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 60
Query: 61 ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS
Sbjct: 61 ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
Query: 121 WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS 180
WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS
Sbjct: 121 WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS 180
Query: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ 240
KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ
Sbjct: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ 240
Query: 241 KRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
KRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN
Sbjct: 241 KRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
>gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens]
Length = 272
Score = 531 bits (1367), Expect = e-151
Identities = 272/272 (100%), Positives = 272/272 (100%)
Query: 1 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 60
MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK
Sbjct: 1 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGK 60
Query: 61 ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS
Sbjct: 61 ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
Query: 121 WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS 180
WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS
Sbjct: 121 WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS 180
Query: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ 240
KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ
Sbjct: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ 240
Query: 241 KRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
KRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN
Sbjct: 241 KRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
Length = 344
Score = 307 bits (786), Expect = 7e-84
Identities = 170/279 (60%), Positives = 200/279 (71%), Gaps = 17/279 (6%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
RV+IGRL+ REKD++RFF GYGR+ ++DLK G+GFVEFED RDADDAVYEL+GKELC
Sbjct: 3 RVYIGRLSYNVREKDIQRFFSGYGRLLEVDLKNGYGFVEFEDSRDADDAVYELNGKELCG 62
Query: 65 ERVTIEHARA--RSRGGRGRGRYSDR--FSSRRPRNDRRNAPPVRTENRLIVENLSSRVS 120
ERV +EHAR R R G G S +SSRR + PPVRTE RLIVENLSSR S
Sbjct: 63 ERVIVEHARGPRRDRDGYSYGSRSGGGGYSSRRTSGRDKYGPPVRTEYRLIVENLSSRCS 122
Query: 121 WQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE-- 178
WQDLKDFMRQAGEVT+ADAH+ + NEGV+EF SY D+K A++KL G EINGR I+LIE
Sbjct: 123 WQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTEINGRNIRLIEDK 182
Query: 179 ----------GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSR 228
GS+ SRSR RSRSR+R SSRSRSRS S+SR S SRSRS+ RSRSRSK R
Sbjct: 183 PRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRSISKSR-SRSRSRSKGRSRSRSKGR 241
Query: 229 SVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
+ RGS S S+S + + ++SRSRSRSRS
Sbjct: 242 KSRSKSKSKPKSDRGSHSHSRSRSKDEYEKSRSRSRSRS 280
Score = 65.5 bits (158), Expect = 5e-11
Identities = 71/251 (28%), Positives = 111/251 (44%), Gaps = 41/251 (16%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKR---GFGFVEFEDPRDADDAVYELDGKE 61
R+ + L+ +D++ F + G + D + G +EF D A+ +LDG E
Sbjct: 111 RLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDGTE 170
Query: 62 LCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
+ + + + R+ R R SRR R+ R+ R+ +R I ++ S S
Sbjct: 171 INGRNIRLIEDKPRTSHRRSYSGSRSRSRSRR-RSRSRSRRSSRSRSRSISKSRSRSRSR 229
Query: 122 QDLKDFMRQAGEVTFADAH-RPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGS 180
+ R G + + + +PK + G S R E S
Sbjct: 230 SKGRSRSRSKGRKSRSKSKSKPKSDRG-----------------SHSHSRSRSKDEYEKS 272
Query: 181 KRHSRSRS---------RSRSRTRSSSRSRS-----RSRSRS-----RKSYSRSRSRSRS 221
+ SRSRS +S+SR+RS SRS S S++RS +++ SRSRSRSRS
Sbjct: 273 RSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSRSRSRSRS 332
Query: 222 RSRSKSRSVSR 232
+SRS+SRS SR
Sbjct: 333 KSRSRSRSSSR 343
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 297 bits (761), Expect = 6e-81
Identities = 168/276 (60%), Positives = 202/276 (73%), Gaps = 18/276 (6%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCS 64
RV+IGRL+ ARE+DVERFFKGYG+I ++DLK G+GFVEF+D RDADDAVYEL+GK+LC
Sbjct: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCG 62
Query: 65 ERVTIEHARARSRGGR---GRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
ERV +EHAR R G GR Y R S R + PP RTE RLIVENLSSR SW
Sbjct: 63 ERVIVEHARGPRRDGSYGSGRSGYGYRRSGRD-----KYGPPTRTEYRLIVENLSSRCSW 117
Query: 122 QDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE--- 178
QDLKD+MRQAGEVT+ADAH+ + NEGV+EF SY D+K A+EKL G E+NGRKI+L+E
Sbjct: 118 QDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRLVEDKP 177
Query: 179 GSKR-----HSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRS 233
GS+R SRS SRSRSR+R S +SRSRS S S+ S+S+SRSRSRS SRS+S+S SRS
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGS-SKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
+S+K S S SK S R S +SRS+S D
Sbjct: 237 QSRSRSKKEKSRSPSKE-KSRSRSHSAGKSRSKSKD 271
Score = 74.3 bits (181), Expect = 1e-13
Identities = 75/280 (26%), Positives = 118/280 (42%), Gaps = 47/280 (16%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRGF---GFVEFEDPRDADDAVYELDGKE 61
R+ + L+ +D++ + + G + D +G G +EF D A+ +LDG E
Sbjct: 105 RLIVENLSSRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTE 164
Query: 62 LCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
+ ++ + + G R R YS S R R+ R++ R+ + SS+ S
Sbjct: 165 VNGRKIRLVEDKP---GSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSG------SSKSSH 215
Query: 122 QDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSK 181
+ R R S +K K SK
Sbjct: 216 SKSRSRSRSGSRSRSKSRSR-----------------------SQSRSRSKKEKSRSPSK 252
Query: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE-KSQ 240
SRSRS S ++RS S+ ++ + ++ + + +SRS SR +SKS+S SRS + +
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEE 312
Query: 241 KRGSSSRSKSPASVDRQ-----------RSRSRSRSRSVD 269
KRGS SR +S RQ RSRSRSRS+S D
Sbjct: 313 KRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKD 352
Score = 61.6 bits (148), Expect = 7e-10
Identities = 72/244 (29%), Positives = 102/244 (41%), Gaps = 48/244 (19%)
Query: 70 EHARARSRG-GRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFM 128
E +R+RS G+ R + D+ + ND P R+ +R ++ SR Q+ +
Sbjct: 253 EKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKS-KSRSRSQERRVEE 311
Query: 129 RQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEIN--GRKIKLIEGSKRHSRS 186
+ G V+ + L + S G ++ S + GRK + E S+ SRS
Sbjct: 312 EKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRK-RSREESRSRSRS 370
Query: 187 RSRS-RSRTRSSSRSRSRSRSRSRKSYSRSRSRSRS------------------------ 221
RS+S RSR R S R S+ +K RS+SRS
Sbjct: 371 RSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGE 430
Query: 222 ----------RSRSKSRSVSRSPVPEKSQKRGSS-----SRSKS---PASVDRQRSRSRS 263
RSRS+S S S+ +P +S+ R S SRSKS AS RSRSRS
Sbjct: 431 SENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRS 490
Query: 264 RSRS 267
SRS
Sbjct: 491 HSRS 494
>gi|5902076 splicing factor, arginine/serine-rich 1 isoform 1 [Homo
sapiens]
Length = 248
Score = 168 bits (426), Expect = 4e-42
Identities = 111/243 (45%), Positives = 138/243 (56%), Gaps = 27/243 (11%)
Query: 4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG---FGFVEFEDPRDADDAVYELD 58
CR+++G L P R KD+E F YG IRDIDLK RG F FVEFEDPRDA+DAVY D
Sbjct: 16 CRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRD 75
Query: 59 GKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSR 118
G + R+ +E R+ GRG GR R P R+ENR++V L
Sbjct: 76 GYDYDGYRLRVEFPRS----GRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPS 131
Query: 119 VSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGR------ 172
SWQDLKD MR+AG+V +AD +R GVVEF D+ A+ KL +
Sbjct: 132 GSWQDLKDHMREAGDVCYADVYRD--GTGVVEFVRKEDMTYAVRKLDNTKFRSHEGETAY 189
Query: 173 -KIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR-----SRSK 226
++K ++G + S RSRSRSR+RS SRSRS SRSR SYS RSR R SRS+
Sbjct: 190 IRVK-VDGPRSPSYGRSRSRSRSRSRSRSRSNSRSR---SYSPRRSRGSPRYSPRHSRSR 245
Query: 227 SRS 229
SR+
Sbjct: 246 SRT 248
>gi|118582269 splicing factor, arginine/serine-rich 1 isoform 2
[Homo sapiens]
Length = 201
Score = 133 bits (334), Expect = 2e-31
Identities = 78/176 (44%), Positives = 99/176 (56%), Gaps = 11/176 (6%)
Query: 4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--RG---FGFVEFEDPRDADDAVYELD 58
CR+++G L P R KD+E F YG IRDIDLK RG F FVEFEDPRDA+DAVY D
Sbjct: 16 CRIYVGNLPPDIRTKDIEDVFYKYGAIRDIDLKNRRGGPPFAFVEFEDPRDAEDAVYGRD 75
Query: 59 GKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSR 118
G + R+ +E R+ GRG GR R P R+ENR++V L
Sbjct: 76 GYDYDGYRLRVEFPRS----GRGTGRGGGGGGGGGAPRGRYGPPSRRSENRVVVSGLPPS 131
Query: 119 VSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKI 174
SWQDLKD MR+AG+V +AD +R GVVEF D+ A+ KL + ++
Sbjct: 132 GSWQDLKDHMREAGDVCYADVYRD--GTGVVEFVRKEDMTYAVRKLDNTKFRSHEV 185
>gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens]
Length = 221
Score = 122 bits (306), Expect = 3e-28
Identities = 84/217 (38%), Positives = 116/217 (53%), Gaps = 27/217 (12%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKRG-----FGFVEFEDPRDADDAVYELDG 59
R+++G L REKD+E F YGRIR+I+LK F FV FEDPRDA+DA+Y +G
Sbjct: 15 RIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNG 74
Query: 60 KELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRV 119
+ R+ +E R + GGRG PR R P R++ R++V L
Sbjct: 75 YDYGQCRLRVEFPR--TYGGRGGW----------PRGGRNGPPTRRSDFRVLVSGLPPSG 122
Query: 120 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEG 179
SWQDLKD MR+AG+V +AD + + G+VE+ D++ A+ KL + K + EG
Sbjct: 123 SWQDLKDHMREAGDVCYADVQKDGV--GMVEYLRKEDMEYALRKL-----DDTKFRSHEG 175
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSR 216
+ R R+ S SRSRS SR R S +SR
Sbjct: 176 ETSYIRVYP---ERSTSYGYSRSRSGSRGRDSPYQSR 209
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 112 bits (281), Expect = 3e-25
Identities = 96/261 (36%), Positives = 122/261 (46%), Gaps = 44/261 (16%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKR---GFGFVEFEDPRDADDAVYELDGKE 61
+V++G L A + ++ER F YG +R + + R GF FVEFEDPRDA+DAV LDGK
Sbjct: 12 KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKV 71
Query: 62 LCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSW 121
+C RV +E S+ PR R + PP R
Sbjct: 72 ICGSRVRVE------------------LSTGMPRRSRFDRPPARRP-------------- 99
Query: 122 QDLKDFMRQAGEVTF--ADAHR-PKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
D D + GE D HR + S+ + S GR+ +
Sbjct: 100 FDPNDRCYECGEKGHYAYDCHRYSRRRRSRSRSRSHSRSRGRRYSRSRSRSRGRRSR--S 157
Query: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSK---SRSVSRSPV 235
S R SRS S RSR+ S RSRS S SR S SRSRSRSRS S+ SRS SRSP
Sbjct: 158 ASPRRSRSISLRRSRSASLRRSRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPS 217
Query: 236 PEKSQK-RGSSSRSKSPASVD 255
P++S+ GS RS SP +D
Sbjct: 218 PKRSRSPSGSPRRSASPERMD 238
Score = 65.9 bits (159), Expect = 4e-11
Identities = 66/196 (33%), Positives = 84/196 (42%), Gaps = 36/196 (18%)
Query: 107 ENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSG 166
E ++ V NL + +L+ G + R VEF D ++A+ L G
Sbjct: 10 ETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDG 69
Query: 167 KEINGRKIK--LIEGSKRHSR---------------------------SRSRSRSRTRSS 197
K I G +++ L G R SR R R RS
Sbjct: 70 KVICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDCHRYSRRRRSR 129
Query: 198 SRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQ 257
SRSRS SRSR R+ YSRSRSRSR R RS+S S RS + R +S R S+
Sbjct: 130 SRSRSHSRSRGRR-YSRSRSRSRGR-RSRSASPRRSRSISLRRSRSASLRRSRSGSIKGS 187
Query: 258 R-----SRSRSRSRSV 268
R SRSRSRSRS+
Sbjct: 188 RYFQSPSRSRSRSRSI 203
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 94.4 bits (233), Expect = 1e-19
Identities = 76/204 (37%), Positives = 103/204 (50%), Gaps = 35/204 (17%)
Query: 99 RNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNE-----GVVEFAS 153
R P V L V+NL+ R S L+ + G V R + + V F
Sbjct: 5 RPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64
Query: 154 YGDLKNAIEKLSGKEINGRKIKLIEG------SKRHSRS--------------RSRS-RS 192
D ++A++ + G ++GR++++ HSR RSRS R
Sbjct: 65 KRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRR 124
Query: 193 RTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ---------KRG 243
R RS SRSRSRSRSRSR YSRS+SRSR+RSRS+S S SRS KS+ +
Sbjct: 125 RRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSR 184
Query: 244 SSSRSKSPASVDRQRSRSRSRSRS 267
S SRS+SP V ++ S+SRSRS+S
Sbjct: 185 SRSRSRSPPPVSKRESKSRSRSKS 208
Score = 72.8 bits (177), Expect = 3e-13
Identities = 75/238 (31%), Positives = 102/238 (42%), Gaps = 58/238 (24%)
Query: 20 VERFFKGYGRIRDIDL--------KRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEH 71
+ R F+ YGR+ D+ + RGF FV F D RDA+DA+ +DG L + ++
Sbjct: 30 LRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQM 89
Query: 72 ARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQA 131
AR GR D SRR PP R R
Sbjct: 90 ARY--------GRPPDSHHSRR-------GPPPR-----------------------RYG 111
Query: 132 GEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSR 191
G + P+ S ++ S + K + S+ S S+SRS
Sbjct: 112 GGGYGRRSRSPRRRR-----RSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSA 166
Query: 192 SRTRSSSRSRSRSRSRSRKSYSRSRSRSR---SRSRSKSRSVSRSPVPEKSQKRGSSS 246
R++S S S SRSRSRSR SRSRSRS S+ SKSRS S+SP P+ ++ G+ S
Sbjct: 167 RRSKSKSSSVSRSRSRSR---SRSRSRSPPPVSKRESKSRSRSKSP-PKSPEEEGAVS 220
>gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens]
Length = 282
Score = 92.0 bits (227), Expect = 5e-19
Identities = 83/259 (32%), Positives = 117/259 (45%), Gaps = 21/259 (8%)
Query: 20 VERFFKGYGRIRDIDLKR--------GFGFVEFEDPRDADDAVYELDGKELCSERVTIEH 71
+ R F+ YGR+ D+ + R GF FV F D RDA DA +DG EL + ++
Sbjct: 30 LRRVFEKYGRVGDVYIPREPHTKAPRGFAFVRFHDRRDAQDAEAAMDGAELDGRELRVQV 89
Query: 72 AR------ARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLK 125
AR RSR G RGR RR R+ R + R +R + S S +
Sbjct: 90 ARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYGRRSRSPRRRHR----SRSRGPSCSRSR 145
Query: 126 DFMRQAGE-VTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHS 184
R G + + R + + Y + + G + S+ HS
Sbjct: 146 SRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRESRYGGSHYSSSGYSNSRYSRYHS 205
Query: 185 RSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGS 244
SRS S+S + +SSRS S S+S S + S+S S SRSRSRS+S S++RSP +K S
Sbjct: 206 -SRSHSKSGSSTSSRSASTSKSSSARR-SKSSSVSRSRSRSRSSSMTRSPPRVSKRKSKS 263
Query: 245 SSRSKSPASVDRQRSRSRS 263
SRSK P + + S
Sbjct: 264 RSRSKRPPKSPEEEGQMSS 282
Score = 58.2 bits (139), Expect = 8e-09
Identities = 75/246 (30%), Positives = 95/246 (38%), Gaps = 81/246 (32%)
Query: 99 RNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNE-------GVVEF 151
R P V L V+NL+ R S L+ + G V D + P+ V F
Sbjct: 5 RPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRV--GDVYIPREPHTKAPRGFAFVRF 62
Query: 152 ASYGDLKNAIEKLSGKEINGRKIKLIE-----------------------GSKRHSRS-- 186
D ++A + G E++GR++++ G R SRS
Sbjct: 63 HDRRDAQDAEAAMDGAELDGRELRVQVARYGRRDLPRSRQGEPRGRSRGGGYGRRSRSYG 122
Query: 187 --------RSRSRSRTRSSSRSRSRSRSR---------SRKSYSRSR------SRSRSR- 222
R RSRSR S SRSRSRSR R SR YSRSR SRSR R
Sbjct: 123 RRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSRYRE 182
Query: 223 -----------------------SRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRS 259
SRS S+S S + S + SS+R +SV R RS
Sbjct: 183 SRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARRSKSSSVSRSRS 242
Query: 260 RSRSRS 265
RSRS S
Sbjct: 243 RSRSSS 248
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 89.0 bits (219), Expect = 4e-18
Identities = 78/282 (27%), Positives = 129/282 (45%), Gaps = 64/282 (22%)
Query: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLK--------RGFGFVEFEDPRDADDAVYEL 57
+F+ + R +D+ R F YG I D+ + RGF +V+FED RDA+DA++ L
Sbjct: 12 LFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNL 71
Query: 58 DGKELCSERVTIEHARA------RSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLI 111
D K +C ++ I+ A+ + + GR YS SSR DR R+ R
Sbjct: 72 DRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYS---SSRYDDYDRYRRSRSRSYER-- 126
Query: 112 VENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171
+ ++ + + ++ P+ N
Sbjct: 127 -------------RRSRSRSFDYNYRRSYSPR--------------------------NS 147
Query: 172 RKIKLIEGSKRHS-----RSRSRSRSRTRSSSRSRSRSR-SRSRKSYSRSRSRSRSRSRS 225
R S+ HS + R+RS SR++S+SRSRS+S+ + K+ SRSRS S +++R
Sbjct: 148 RPTGRPRRSRSHSDNDRFKHRNRSFSRSKSNSRSRSKSQPKKEMKAKSRSRSASHTKTRG 207
Query: 226 KSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
S++ S++ S+ S + + P S + RS+SRSRS+S
Sbjct: 208 TSKTDSKTHYKSGSRYEKESRKKEPPRSKSQSRSQSRSRSKS 249
>gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens]
Length = 164
Score = 86.3 bits (212), Expect = 3e-17
Identities = 70/212 (33%), Positives = 88/212 (41%), Gaps = 62/212 (29%)
Query: 4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDLKR---GFGFVEFEDPRDADDAVYELDGK 60
C+V++G L + ++ER F YG +R + + R GF FVEFEDPRDA DAV ELDG+
Sbjct: 10 CKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGR 69
Query: 61 ELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRND--RRNAPPVRTENRLIVENLSSR 118
LC RV +E + R R R RRPR+D RR+ PP R R
Sbjct: 70 TLCGCRVRVELSNGEK---RSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPR--------- 117
Query: 119 VSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
+ F R D R +
Sbjct: 118 -----RRSFSRSRSRSLSRDRRRER----------------------------------- 137
Query: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRK 210
S SR R+ +RS SRSRSRSRS RK
Sbjct: 138 -----SLSRERNHKPSRSFSRSRSRSRSNERK 164
Score = 61.2 bits (147), Expect = 9e-10
Identities = 50/127 (39%), Positives = 66/127 (51%), Gaps = 25/127 (19%)
Query: 149 VEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRS-----RTRSSSRSRS- 202
VEF D +A+ +L G+ + G +++ +E S RSR+R R R R RS
Sbjct: 51 VEFEDPRDAADAVRELDGRTLCGCRVR-VELSNGEKRSRNRGPPPSWGRRPRDDYRRRSP 109
Query: 203 --RSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSR 260
R RS R+S+SRSRSRS SR R + RS+SR R+ P+ R SR
Sbjct: 110 PPRRRSPRRRSFSRSRSRSLSRDRRRERSLSRE-------------RNHKPS---RSFSR 153
Query: 261 SRSRSRS 267
SRSRSRS
Sbjct: 154 SRSRSRS 160
>gi|148612890 serine-arginine repressor protein [Homo sapiens]
Length = 261
Score = 85.1 bits (209), Expect = 6e-17
Identities = 84/272 (30%), Positives = 130/272 (47%), Gaps = 41/272 (15%)
Query: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDLK--------RGFGFVEFEDPRDADDAVYEL 57
+FI + A R +D+ R F YG I D+ + RGF +V+FED RDA+DA+Y L
Sbjct: 12 LFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71
Query: 58 DGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSS 117
+ K +C ++ I+ A+ R G+ + +R P + RR+ P + R S
Sbjct: 72 NRKWVCGRQIEIQFAQG-DRKTPGQMKSKERHPC-SPSDHRRSRSPSQRRTR------SR 123
Query: 118 RVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLI 177
SW R+ + HR SY K+ + L + + R+ +
Sbjct: 124 SSSW----GRNRRRSDSLKESRHRR---------FSYSQSKSRSKSLPRRSTSARQSRT- 169
Query: 178 EGSKRHSRSRSRSRSRT---RSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234
+R+ SR RSRS++ RS S +S+S S +++ S ++SRS R S S++RSP
Sbjct: 170 --PRRNFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGR---HSDSIARSP 224
Query: 235 VPEKSQKRGSSSRSK-SPASVDRQRSRSRSRS 265
KS K ++S +K A RS SRSRS
Sbjct: 225 C--KSPKGYTNSETKVQTAKHSHFRSHSRSRS 254
Score = 58.5 bits (140), Expect = 6e-09
Identities = 50/147 (34%), Positives = 78/147 (53%), Gaps = 31/147 (21%)
Query: 149 VEFASYGDLKNAIEKLSGKEINGRKIKL------------IEGSKRH---------SRSR 187
V+F D ++A+ L+ K + GR+I++ ++ +RH SRS
Sbjct: 56 VQFEDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDHRRSRSP 115
Query: 188 SRSRSRTRSSSRSRSRSRSRSRK-------SYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ 240
S+ R+R+RSSS R+R RS S K SYS+S+SRS+S R +S S +S P ++
Sbjct: 116 SQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPR-RSTSARQSRTPRRN- 173
Query: 241 KRGSSSRSKSPASVDRQRSRSRSRSRS 267
GS RS+S + R +S +S+S S
Sbjct: 174 -FGSRGRSRSKSLQKRSKSIGKSQSSS 199
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 80.1 bits (196), Expect = 2e-15
Identities = 46/93 (49%), Positives = 56/93 (60%), Gaps = 1/93 (1%)
Query: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEK 238
G R SRSR R R R RS SR + RSRSR RK RSRSR R RSR + RS SR +
Sbjct: 35 GDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSR 94
Query: 239 SQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSG 271
S+ RG SRS SP + + ++ +RSRS+ G
Sbjct: 95 SRSRGRRSRSSSPGNKSK-KTENRSRSKEKTDG 126
Score = 58.2 bits (139), Expect = 8e-09
Identities = 46/107 (42%), Positives = 54/107 (50%), Gaps = 21/107 (19%)
Query: 187 RSRSRSRTRSSSRSRSRSRSRSRK-----------SYSRSRSRSRSRSRSKSRSVSRSPV 235
R R RS+SR RS SRSRSR SRSR R R R RS+SR RS
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRS 62
Query: 236 PEKSQKRGSSSRSKSPA-------SVDRQRSRSRS---RSRSVDSGN 272
++ + R S SR + + S DR+RSRSRS RSRS GN
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGN 109
Score = 54.3 bits (129), Expect = 1e-07
Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 6/101 (5%)
Query: 172 RKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRS------RSRSRSRSRS 225
R K + S+ R RSR R R+RS R RSRSRSR R+S S S ++ +RSRS+
Sbjct: 63 RDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKE 122
Query: 226 KSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSR 266
K+ S +K + + K + D+ + R R
Sbjct: 123 KTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKR 163
Score = 50.8 bits (120), Expect = 1e-06
Identities = 41/102 (40%), Positives = 54/102 (52%), Gaps = 18/102 (17%)
Query: 181 KRHSRSR-------SRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRS 233
KR SRSR SRSR R RS R RSRSR R R+S SRSR R RSRS S ++
Sbjct: 57 KRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDR-RRSRSRSRGR-RSRSSSPGNKSKKT 114
Query: 234 PVPEKSQKR---GSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
+S+++ G SS+ K D++ + + D+GN
Sbjct: 115 ENRSRSKEKTDGGESSKEKKKDKDDKEDEKEK------DAGN 150
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 79.0 bits (193), Expect = 4e-15
Identities = 51/82 (62%), Positives = 58/82 (70%), Gaps = 1/82 (1%)
Query: 184 SRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG 243
SRSRSRS+SR RSSSRS SRS S+S SYSRSRSRS SRS S+SRS SRS +
Sbjct: 737 SRSRSRSKSRGRSSSRSNSRS-SKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSR 795
Query: 244 SSSRSKSPASVDRQRSRSRSRS 265
S SRS+S + +R RSRSRS
Sbjct: 796 SQSRSRSKSYSPGRRRRSRSRS 817
Score = 73.2 bits (178), Expect = 2e-13
Identities = 48/94 (51%), Positives = 59/94 (62%), Gaps = 3/94 (3%)
Query: 163 KLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR 222
K G+ + + + S +SRSRSRS SR+ S SRSRSRSRSRS +S SRS+SRSRS+
Sbjct: 744 KSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSK 803
Query: 223 SRS---KSRSVSRSPVPEKSQKRGSSSRSKSPAS 253
S S + RS SRSP P S GS+S P S
Sbjct: 804 SYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDS 837
Score = 58.2 bits (139), Expect = 8e-09
Identities = 42/77 (54%), Positives = 48/77 (62%), Gaps = 9/77 (11%)
Query: 195 RSSSRSRSRSRSRSRKSY-SRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPA- 252
R+ R+R R R S SRSRSRS+SR RS SRS SRS S+ GS SRS+S +
Sbjct: 718 RAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRS-----SKSSGSYSRSRSRSC 772
Query: 253 --SVDRQRSRSRSRSRS 267
S R RSRSRSRSRS
Sbjct: 773 SRSYSRSRSRSRSRSRS 789
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 76.3 bits (186), Expect = 3e-14
Identities = 55/110 (50%), Positives = 66/110 (60%), Gaps = 19/110 (17%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
+ +K+ S RSRS+SR SS SRS SRS S S SRSRSRSRSRS S S+S SRS E
Sbjct: 192 DSNKKKSNRRSRSKSR---SSHSRSSSRSSSPSS-SRSRSRSRSRSSSSSQSRSRSSSRE 247
Query: 238 KSQKRGSSSRSK---------------SPASVDRQRSRSRSRSRSVDSGN 272
+S+ RGS SRS S +S +R+R RSRSRS SG+
Sbjct: 248 RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/92 (57%), Positives = 64/92 (69%), Gaps = 9/92 (9%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRS----RSRSRKSYSRSRSRS-RSRSRSKSRSV-SRS 233
S SRSRSRSRSR+ SSS+SRSRS RSRSR S SRS SRS R S + RS S S
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS 278
Query: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
PE+++KR SRS+S +S DR++ R+RSRS
Sbjct: 279 SSPERNRKR---SRSRSSSSGDRKKRRTRSRS 307
Score = 70.5 bits (171), Expect = 2e-12
Identities = 62/135 (45%), Positives = 75/135 (55%), Gaps = 30/135 (22%)
Query: 162 EKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKS-YSRSRSRSR 220
E+ S K+ + R+ + R S SRS SRS + SSSRSRSRSRSRS S SRSRS SR
Sbjct: 190 EEDSNKKKSNRRSR---SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246
Query: 221 SRSRS---KSRSVSRS----------------PVPEKSQKRGSSSRSKSPASVDRQ---- 257
RSRS KSRS SRS PE+++KR SRS+S +S DR+
Sbjct: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKR---SRSRSSSSGDRKKRRT 303
Query: 258 RSRSRSRSRSVDSGN 272
RSRS R SG+
Sbjct: 304 RSRSPERRHRSSSGS 318
Score = 52.0 bits (123), Expect = 6e-07
Identities = 42/87 (48%), Positives = 49/87 (56%), Gaps = 16/87 (18%)
Query: 180 SKRHSRSRSRSR-SRTRSSSRSRSRSRSRSRKSYS-------RSRSRSRSRS-----RSK 226
S+ SR RSRSR S++RSSSRS S S ++SYS R+R RSRSRS R K
Sbjct: 241 SRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKK 300
Query: 227 SRSVSRSPVPEKSQKRGSS---SRSKS 250
R+ SRSP GSS SRS S
Sbjct: 301 RRTRSRSPERRHRSSSGSSHSGSRSSS 327
Score = 49.3 bits (116), Expect = 4e-06
Identities = 64/223 (28%), Positives = 88/223 (39%), Gaps = 34/223 (15%)
Query: 11 LNPAAREKDVE-RFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTI 69
+ PA+ K+VE + +G D DL + + E ED DAD + Y LD E
Sbjct: 139 VGPASILKEVEDKESEGEEEDEDEDLSK-YKLDEDEDEDDADLSKYNLDASEEEDSNKKK 197
Query: 70 EHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129
+ R+RS+ R S R SS P + +R + SS S + R
Sbjct: 198 SNRRSRSKSRSSHSRSSSRSSS-----------PSSSRSRSRSRSRSSSSSQSRSRSSSR 246
Query: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSR 189
+ S G + + + RK S R+R R
Sbjct: 247 ERSR-------------------SRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKR 287
Query: 190 SRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSR 232
SRSR+ SSS R + R+RSR R RS S S S S SRS S+
Sbjct: 288 SRSRS-SSSGDRKKRRTRSRSPERRHRSSSGS-SHSGSRSSSK 328
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 76.3 bits (186), Expect = 3e-14
Identities = 55/110 (50%), Positives = 66/110 (60%), Gaps = 19/110 (17%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
+ +K+ S RSRS+SR SS SRS SRS S S SRSRSRSRSRS S S+S SRS E
Sbjct: 192 DSNKKKSNRRSRSKSR---SSHSRSSSRSSSPSS-SRSRSRSRSRSSSSSQSRSRSSSRE 247
Query: 238 KSQKRGSSSRSK---------------SPASVDRQRSRSRSRSRSVDSGN 272
+S+ RGS SRS S +S +R+R RSRSRS SG+
Sbjct: 248 RSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGD 297
Score = 73.6 bits (179), Expect = 2e-13
Identities = 53/92 (57%), Positives = 64/92 (69%), Gaps = 9/92 (9%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRS----RSRSRKSYSRSRSRS-RSRSRSKSRSV-SRS 233
S SRSRSRSRSR+ SSS+SRSRS RSRSR S SRS SRS R S + RS S S
Sbjct: 219 SPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSS 278
Query: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
PE+++KR SRS+S +S DR++ R+RSRS
Sbjct: 279 SSPERNRKR---SRSRSSSSGDRKKRRTRSRS 307
Score = 70.9 bits (172), Expect = 1e-12
Identities = 60/131 (45%), Positives = 72/131 (54%), Gaps = 24/131 (18%)
Query: 162 EKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKS-YSRSRSRSR 220
E+ S K+ + R+ + R S SRS SRS + SSSRSRSRSRSRS S SRSRS SR
Sbjct: 190 EEDSNKKKSNRRSR---SKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSR 246
Query: 221 SRSRS---KSRSVSRS----------------PVPEKSQKRGSSSRSKSPASVDRQRSRS 261
RSRS KSRS SRS PE+++KR S SRS S ++R+RS
Sbjct: 247 ERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKR-SRSRSSSSGDRKKRRTRS 305
Query: 262 RSRSRSVDSGN 272
RS V N
Sbjct: 306 RSPESQVIGEN 316
Score = 45.1 bits (105), Expect = 7e-05
Identities = 61/224 (27%), Positives = 83/224 (37%), Gaps = 54/224 (24%)
Query: 11 LNPAAREKDVE-RFFKGYGRIRDIDLKRGFGFVEFEDPRDADDAVYELDGKELCSERVTI 69
+ PA+ K+VE + +G D DL + + E ED DAD + Y LD E
Sbjct: 139 VGPASILKEVEDKESEGEEEDEDEDLSK-YKLDEDEDEDDADLSKYNLDASEEEDSNKKK 197
Query: 70 EHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129
+ R+RS+ R S R SS P + R R+ +R + S S ++ R
Sbjct: 198 SNRRSRSKSRSSHSRSSSRSSS--PSSSRS-----RSRSRSRSSSSSQSRSRSSSRERSR 250
Query: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSR 189
G + S R R S
Sbjct: 251 SRGSKS------------------------------------------RSSSRSHRGSSS 268
Query: 190 SRSRTRSSSRS---RSRSRSRSRKSYSRSRSRSRSRSRSKSRSV 230
R R+ SSS S R+R RSRSR S S R + R+RSRS V
Sbjct: 269 PRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPESQV 312
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 75.9 bits (185), Expect = 4e-14
Identities = 54/105 (51%), Positives = 68/105 (64%), Gaps = 9/105 (8%)
Query: 165 SGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSR 224
+G++ + RK + + HSRSRSR R R RS SR R +SRSRSR+ R +SRSRSR R
Sbjct: 48 NGEDRHKRKERKSSRGRSHSRSRSRER-RHRSRSRERKKSRSRSRE---RKKSRSRSRER 103
Query: 225 SKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
KSRS SR E+ ++ S SRS+S R RSRSR+RSRS D
Sbjct: 104 KKSRSRSR----ERKRRIRSRSRSRSRHR-HRTRSRSRTRSRSRD 143
Score = 70.1 bits (170), Expect = 2e-12
Identities = 49/118 (41%), Positives = 65/118 (55%), Gaps = 9/118 (7%)
Query: 158 KNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRS 217
K+ E+ + KE + K + S + R + + R S RS SRSRSR R+ SRSR
Sbjct: 23 KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRE 82
Query: 218 RSRSRSRSKSRSVSRSPVPEKSQKRGSS--------SRSKSPASVDRQRSRSRSRSRS 267
R +SRSRS+ R SRS E+ + R S SRS+S S R R+RSRSR+RS
Sbjct: 83 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRS-RSRHRHRTRSRSRTRS 139
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/86 (48%), Positives = 52/86 (60%), Gaps = 4/86 (4%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
E K SRSR R +SR+RS R +SRSRSR RK RSRSRSRSR R ++RS SR+
Sbjct: 82 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT---- 137
Query: 238 KSQKRGSSSRSKSPASVDRQRSRSRS 263
+S+ R R + P R SR+ S
Sbjct: 138 RSRSRDRKKRIEKPRRFSRSLSRTPS 163
Score = 66.2 bits (160), Expect = 3e-11
Identities = 46/91 (50%), Positives = 55/91 (60%), Gaps = 5/91 (5%)
Query: 181 KRH-SRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRS---RSRSKSRSVSRSPVP 236
+RH SRSR R +SR+RS R +SRSRSR RK SRSRSR R RSRS+SRS R
Sbjct: 74 RRHRSRSRERKKSRSRSRERKKSRSRSRERKK-SRSRSRERKRRIRSRSRSRSRHRHRTR 132
Query: 237 EKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
+S+ R S K R+ SRS SR+ S
Sbjct: 133 SRSRTRSRSRDRKKRIEKPRRFSRSLSRTPS 163
Score = 63.9 bits (154), Expect = 1e-10
Identities = 48/109 (44%), Positives = 62/109 (56%), Gaps = 8/109 (7%)
Query: 162 EKLSGKEINGRKIKLIEGSKRHSRSRS---RSRSRTRSSSRSRSRSRSRSRKSYSRSRSR 218
+K +E N ++ +G +R + S + R + + R SSR RS SRSRSR+ R R
Sbjct: 22 KKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRER----RHR 77
Query: 219 SRSRSRSKSRSVSRSPVPEKSQKR-GSSSRSKSPASVDRQRSRSRSRSR 266
SRSR R KSRS SR +S+ R SRS+S R RSRSRSRSR
Sbjct: 78 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
Score = 55.1 bits (131), Expect = 7e-08
Identities = 37/104 (35%), Positives = 54/104 (51%), Gaps = 3/104 (2%)
Query: 163 KLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR 222
K S RK +R R RSRSRSR+R R+RSRSR+RSR SR R + +
Sbjct: 94 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSR---SRDRKKRIEK 150
Query: 223 SRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSR 266
R SRS+SR+P P + R ++ ++ + +R++ R
Sbjct: 151 PRRFSRSLSRTPSPPPFRGRNTAMDAQEALARRLERAKKLQEQR 194
Score = 45.8 bits (107), Expect = 4e-05
Identities = 31/94 (32%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVS-----R 232
+ SK+H + + R R S + R + R SR RS SRS S R
Sbjct: 19 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKR-KERKSSRGRSHSRSRSRERRHR 77
Query: 233 SPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSR 266
S E+ + R S K S R+R +SRSRSR
Sbjct: 78 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 111
Score = 28.9 bits (63), Expect = 5.0
Identities = 20/74 (27%), Positives = 25/74 (33%), Gaps = 12/74 (16%)
Query: 193 RTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPA 252
R S +S + +S S + R R S R E+ RG
Sbjct: 13 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG--------- 63
Query: 253 SVDRQRSRSRSRSR 266
R SRSRSR R
Sbjct: 64 ---RSHSRSRSRER 74
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 75.9 bits (185), Expect = 4e-14
Identities = 54/105 (51%), Positives = 68/105 (64%), Gaps = 9/105 (8%)
Query: 165 SGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSR 224
+G++ + RK + + HSRSRSR R R RS SR R +SRSRSR+ R +SRSRSR R
Sbjct: 107 NGEDRHKRKERKSSRGRSHSRSRSRER-RHRSRSRERKKSRSRSRE---RKKSRSRSRER 162
Query: 225 SKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
KSRS SR E+ ++ S SRS+S R RSRSR+RSRS D
Sbjct: 163 KKSRSRSR----ERKRRIRSRSRSRSRHR-HRTRSRSRTRSRSRD 202
Score = 70.1 bits (170), Expect = 2e-12
Identities = 42/86 (48%), Positives = 52/86 (60%), Gaps = 4/86 (4%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
E K SRSR R +SR+RS R +SRSRSR RK RSRSRSRSR R ++RS SR+
Sbjct: 141 ERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRT---- 196
Query: 238 KSQKRGSSSRSKSPASVDRQRSRSRS 263
+S+ R R + P R SR+ S
Sbjct: 197 RSRSRDRKKRIEKPRRFSRSLSRTPS 222
Score = 60.5 bits (145), Expect = 2e-09
Identities = 61/210 (29%), Positives = 98/210 (46%), Gaps = 34/210 (16%)
Query: 73 RARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAG 132
R+RSR GR S SS++ +++ N ++ E L+S + G
Sbjct: 62 RSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGR--ERLNSS-----------ENG 108
Query: 133 EVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRS 192
E D H+ K + S+ ++ + + +K + ++ SRSRSR R
Sbjct: 109 E----DRHKRKERKSS-RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERK 163
Query: 193 RTRSSSRSR-----SRSRSRSR---KSYSRSRSRSRSRSRSK--------SRSVSRSPVP 236
++RS SR R SRSRSRSR ++ SRSR+RSRSR R K SRS+SR+P P
Sbjct: 164 KSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSP 223
Query: 237 EKSQKRGSSSRSKSPASVDRQRSRSRSRSR 266
+ R ++ ++ + +R++ R
Sbjct: 224 PPFRGRNTAMDAQEALARRLERAKKLQEQR 253
Score = 47.8 bits (112), Expect = 1e-05
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 16/99 (16%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKS 239
+ +H SRSRSRSR R + +S + RK SRSRS+ R SK +S + E +
Sbjct: 35 ASKHHYSRSRSRSRER-----KRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHN 89
Query: 240 QKRGSSSRSKSPAS-----------VDRQRSRSRSRSRS 267
K SS + + + +R+ SR RS SRS
Sbjct: 90 DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRS 128
Score = 42.4 bits (98), Expect = 4e-04
Identities = 32/92 (34%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ 240
K+ +S R SRSRSRSR RK S + R + RSRS+S+ R +KS
Sbjct: 22 KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGR-KHRSRSRSKEGRRHESKDKSS 80
Query: 241 KRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
K + KS D++ S + R R S N
Sbjct: 81 K-----KHKSEEHNDKEHSSDKGRERLNSSEN 107
Score = 37.0 bits (84), Expect = 0.018
Identities = 28/83 (33%), Positives = 35/83 (42%), Gaps = 2/83 (2%)
Query: 190 SRSRTRSSSRSR-SRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRS 248
S R + +S S S S+ YSRSRSRSR R R KS + R K G S
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKR-KSDNEGRKHRSRSRSKEGRRHES 75
Query: 249 KSPASVDRQRSRSRSRSRSVDSG 271
K +S + + S D G
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSDKG 98
>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing B [Homo sapiens]
Length = 546
Score = 74.7 bits (182), Expect = 8e-14
Identities = 81/247 (32%), Positives = 118/247 (47%), Gaps = 31/247 (12%)
Query: 36 KRGFGFVEF--EDPRDADDAVYELDGKELCSERVTIEHARARSRG-----GRGRGRYSDR 88
+ G G F E R+ + E + KE ER +R+ RG R R R+ R
Sbjct: 283 REGHGSSSFDRELEREKERQRLEREAKEREKER---RRSRSIDRGLERRRSRSRERHRSR 339
Query: 89 FSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGV 148
SR + DRR+ R E + R +D +D+ ++ G + R + E
Sbjct: 340 SRSRDRKGDRRDRDRER-------EKENERGRRRD-RDYDKERGNER--EKERERSRERS 389
Query: 149 VEFASYGDLKNAIEKLSGKEINGRKIKL-IEGSKRHSRSRSRSRS-RTRSSSRS---RSR 203
E S G+++ K + R K + K+HSRSRSR R R+RS SR+ RSR
Sbjct: 390 KEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSR 449
Query: 204 SRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKR-GSSSRSKSPASVDRQRSRSR 262
SRS+ + S ++ S+ +S RS+S S R+ EKS+KR S S+ KS R+RSRS+
Sbjct: 450 SRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKS-----RKRSRSK 504
Query: 263 SRSRSVD 269
RS D
Sbjct: 505 ERSHKRD 511
Score = 52.0 bits (123), Expect = 6e-07
Identities = 52/196 (26%), Positives = 78/196 (39%), Gaps = 4/196 (2%)
Query: 70 EHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129
E R+RSR +G DR R N+R + E R ++ R
Sbjct: 334 ERHRSRSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQR 393
Query: 130 QAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSR 189
GEV K + + + + +E R + + SRSRS+
Sbjct: 394 SRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSK 453
Query: 190 SRS---RTRSSSRSRSRSRSRSR-KSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSS 245
+S + S +S RSRS S+ ++ S +S+ R S SK +S RS E+S KR S
Sbjct: 454 EKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHS 513
Query: 246 SRSKSPASVDRQRSRS 261
DR+RS+S
Sbjct: 514 DSKDQSDKHDRRRSQS 529
Score = 50.1 bits (118), Expect = 2e-06
Identities = 34/92 (36%), Positives = 43/92 (46%), Gaps = 3/92 (3%)
Query: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRS---RKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
+R SRS RS S RS RSRSRS R S+ R R + R R + + R
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERR 316
Query: 238 KSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
+S+ + S +R RSRSRSR R D
Sbjct: 317 RSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348
Score = 50.1 bits (118), Expect = 2e-06
Identities = 51/153 (33%), Positives = 60/153 (39%), Gaps = 53/153 (34%)
Query: 172 RKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSR---------------------- 209
R+ K E +R SRS R R RS SR R RSRSRSR
Sbjct: 306 REAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDREREKENERGRR 365
Query: 210 --------KSYSRSRSRSRSRSRSKSRSVSRSPVPEK-----------------SQKRGS 244
+ R + R RSR RSK + SR V EK S+K
Sbjct: 366 RDRDYDKERGNEREKERERSRERSKEQR-SRGEVEEKKHKEDKDDRRHRDDKRDSKKEKK 424
Query: 245 SSRSKSPASVDRQRSRSR-----SRSRSVDSGN 272
SRS+S R RSRSR SRSRS + +
Sbjct: 425 HSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSS 457
Score = 33.9 bits (76), Expect = 0.16
Identities = 25/90 (27%), Positives = 35/90 (38%), Gaps = 16/90 (17%)
Query: 198 SRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDR- 256
+R R + + R R RSRS RS+S P +S+ R +S DR
Sbjct: 235 TRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRE 294
Query: 257 ---------------QRSRSRSRSRSVDSG 271
+R + R RSRS+D G
Sbjct: 295 LEREKERQRLEREAKEREKERRRSRSIDRG 324
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 74.3 bits (181), Expect = 1e-13
Identities = 72/206 (34%), Positives = 99/206 (48%), Gaps = 33/206 (16%)
Query: 70 EHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR 129
EH+R+RSR GR R+S SSRR + +A ++ + S S+ D D R
Sbjct: 848 EHSRSRSRSGR---RHSSHRSSRRSYSSSSDASS--DQSCYSRQRSYSDDSYSDYSDRSR 902
Query: 130 QAGEVTF--------ADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSK 181
+ + + + HR K ++ Y LS + R S+
Sbjct: 903 RHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYS--------LSCSQSRSR-------SR 947
Query: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQK 241
H+R RSRSR R+RSSS SRSRS+ RSR + + S RSRS SR +SRS +RSP SQ+
Sbjct: 948 SHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRS-TRSP----SQR 1002
Query: 242 RGSSSRSKSPASVDRQRSRSRSRSRS 267
GS RS S + + S R RS
Sbjct: 1003 SGSRKRSWGHESPEERHSGRRDFIRS 1028
Score = 48.1 bits (113), Expect = 8e-06
Identities = 38/93 (40%), Positives = 49/93 (52%), Gaps = 14/93 (15%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSR--SRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
S+RHS+ S +SS+ RS+ S S YS S S+SRSRSRS +R E
Sbjct: 901 SRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTR--------E 952
Query: 238 KSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDS 270
+S+ RG S S S R RS+ RSRS + S
Sbjct: 953 RSRSRGRSRSS----SCSRSRSKRRSRSTTAHS 981
Score = 44.3 bits (103), Expect = 1e-04
Identities = 52/155 (33%), Positives = 58/155 (37%), Gaps = 62/155 (40%)
Query: 178 EGSKRHSRSRSRS---RSRTRSSSRS-------------RSRSRSRSRKSYSRSRSRSRS 221
+ HSRSRSRS S RSS RS SR RS S SYS RSR
Sbjct: 844 DSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRR 903
Query: 222 RSR---------------------------------SKSRSVSRSPVPEKSQKRGSS--- 245
S+ S+SRS SRS E+S+ RG S
Sbjct: 904 HSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRGRSRSS 963
Query: 246 ----------SRSKSPASVDRQRSRSRSRSRSVDS 270
SRS + S R RS SR RSRS S
Sbjct: 964 SCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRS 998
Score = 38.9 bits (89), Expect = 0.005
Identities = 43/112 (38%), Positives = 48/112 (42%), Gaps = 20/112 (17%)
Query: 179 GSKRHSRSRSRSR-------SRTRSSSRSRSRSRSR---------SRKSYSRSRSRS--- 219
G+KR SRS RS+ S SS R +S S+ S +SRSRSRS
Sbjct: 800 GTKRSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRR 859
Query: 220 RSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRS-RSVDS 270
S RS RS S S Q S RS S S RSR S RS DS
Sbjct: 860 HSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDS 911
Score = 38.5 bits (88), Expect = 0.006
Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 5/118 (4%)
Query: 160 AIEKLSGK--EINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRS 217
A E SGK E G G ++H S + R+ ++ SRS RS+ S S
Sbjct: 761 AEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDS 820
Query: 218 RSRSRSRSKSRSVSRSPVPEKSQKRGSS---SRSKSPASVDRQRSRSRSRSRSVDSGN 272
S R +S S+ E+ + GS SRS+S RS RS S S D+ +
Sbjct: 821 DDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASS 878
Score = 35.4 bits (80), Expect = 0.053
Identities = 20/82 (24%), Positives = 30/82 (36%)
Query: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEK 238
G S + RS RS R + +K + +S R S++ EK
Sbjct: 648 GGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEK 707
Query: 239 SQKRGSSSRSKSPASVDRQRSR 260
S+KR R K+ +S R
Sbjct: 708 SKKRKKRKRKKNKSSAPADSER 729
Score = 34.3 bits (77), Expect = 0.12
Identities = 31/88 (35%), Positives = 36/88 (40%), Gaps = 2/88 (2%)
Query: 183 HSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKR 242
H +S S+ SRSRSR S RS RS S S S S S++R
Sbjct: 829 HQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDAS-SDQSCYSRQR 887
Query: 243 GSSSRSKSPASVDRQRSRSRSRSRSVDS 270
S S S S DR R S+ S DS
Sbjct: 888 SYSDDSYSDYS-DRSRRHSKRSHDSDDS 914
Score = 33.1 bits (74), Expect = 0.27
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 11/108 (10%)
Query: 165 SGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSR 224
SGK +K K + S +H R SS++ S +S+ RK R +++S + +
Sbjct: 669 SGKSHRHKKKKKHKKSSKHKRKHKADTE--EKSSKAESGEKSKKRKKRKRKKNKSSAPAD 726
Query: 225 SKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
S+ R P PE GS S + P R + S+ RS + G+
Sbjct: 727 SE-----RGPKPEPP---GSGSPA-PPRRRRRAQDDSQRRSLPAEEGS 765
>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
Length = 484
Score = 73.9 bits (180), Expect = 1e-13
Identities = 62/166 (37%), Positives = 85/166 (51%), Gaps = 24/166 (14%)
Query: 110 LIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEI 169
L+ +L S S +++++ M++ E + ++ A D K + S
Sbjct: 205 LVSPSLKSDTSSKEIEEAMKRVREA-----------QSLISAAIEPDKKEEKRRHSRSRS 253
Query: 170 NGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRS-RSRKSYSRSRSRSRSRSRSKSR 228
R+ + S RH RSRSRSR R+ S SRSR RS+S R R+S+SR R R RSRS SK+R
Sbjct: 254 RSRR-RRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGR-RSRSTSKTR 311
Query: 229 -------SVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
RS P KS SRS AS +R+R RSRS +RS
Sbjct: 312 DKKKEDKEKKRSKTPPKSYSTARRSRS---ASRERRRRRSRSGTRS 354
Score = 59.3 bits (142), Expect = 3e-09
Identities = 48/115 (41%), Positives = 61/115 (53%), Gaps = 27/115 (23%)
Query: 181 KRHSRSRSRSRS----RTRSSSRS---RSRSRSRSR----------------KSYS---R 214
+ HS+SRSR RS R RS SR RSRS S++R KSYS R
Sbjct: 276 RSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR 335
Query: 215 SRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
SRS SR R R +SRS +RSP +S KR SRS SP +++ + + + RS D
Sbjct: 336 SRSASRERRRRRSRSGTRSPKKPRSPKR-KLSRSPSPRRHKKEKKKDKDKERSRD 389
Score = 46.2 bits (108), Expect = 3e-05
Identities = 55/201 (27%), Positives = 80/201 (39%), Gaps = 33/201 (16%)
Query: 71 HARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQ 130
H+R+RSR R R S R R R+ RR+ R+ R S + + R+
Sbjct: 248 HSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRR--------SKSPRRRRSHSRE 299
Query: 131 AGEVTFADAH-RPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSR 189
G + + + R K E D + K K + + R SRS SR
Sbjct: 300 RGRRSRSTSKTRDKKKE---------DKEKKRSKTPPKSYS---------TARRSRSASR 341
Query: 190 SRSRTRSSSRSRSRSRSRS-RKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRS 248
R R RS S +RS + RS ++ SRS S R + K + E+S+ S S
Sbjct: 342 ERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKK-----KDKDKERSRDERERSTS 396
Query: 249 KSPASVDRQRSRSRSRSRSVD 269
K S D+++ R R D
Sbjct: 397 KKKKSKDKEKDRERKSESDKD 417
Score = 36.6 bits (83), Expect = 0.024
Identities = 43/204 (21%), Positives = 82/204 (40%), Gaps = 12/204 (5%)
Query: 71 HARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMR- 129
H R+RSR R +S S RR ++ RR R R +R ++ K+ R
Sbjct: 266 HRRSRSRSRRRS--HSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRS 323
Query: 130 QAGEVTFADAHRPK-LNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRS 188
+ +++ A R + + S ++ + S K RK+ +RH + +
Sbjct: 324 KTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPK----RKLSRSPSPRRHKKEKK 379
Query: 189 RSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG-SSSR 247
+ + + RS R RS S+K S+ + + R R + V + +++G S +
Sbjct: 380 KDKDKERSRD---ERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQGYDSEK 436
Query: 248 SKSPASVDRQRSRSRSRSRSVDSG 271
K + +++ SV+ G
Sbjct: 437 EKKEEKKPIETGSPKTKECSVEKG 460
>gi|187960109 RNA binding motif protein 28 [Homo sapiens]
Length = 759
Score = 70.9 bits (172), Expect = 1e-12
Identities = 52/187 (27%), Positives = 86/187 (45%), Gaps = 14/187 (7%)
Query: 1 MSGCRVFIGRLNPAAREKDVERFFKGYGRIRDIDLK--------RGFGFVEFEDPRDADD 52
M+G +F+GRL P+AR + +E F G ++ + RGFG+V F D
Sbjct: 1 MAGLTLFVGRLPPSARSEQLEELFSQVGPVKQCFVVTEKGSKACRGFGYVTFSMLEDVQR 60
Query: 53 AVYELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIV 112
A+ E+ E C VT+ + R++ + + P+ + A + RLI+
Sbjct: 61 ALKEITTFEGCKINVTVAKKKLRNKTKEKGKNENSECPKKEPK--AKKAKVADKKARLII 118
Query: 113 ENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGR 172
NLS + S DLK Q G V + + P+ +G + + KN +E +GK + G
Sbjct: 119 RNLSFKCSEDDLKTVFAQFGAV--LEVNIPRKPDGKMRGFGFVQFKNLLE--AGKALKGM 174
Query: 173 KIKLIEG 179
+K I+G
Sbjct: 175 NMKEIKG 181
Score = 37.4 bits (85), Expect = 0.014
Identities = 21/80 (26%), Positives = 43/80 (53%), Gaps = 7/80 (8%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDLKR-------GFGFVEFEDPRDADDAVYEL 57
R+ I L+ E D++ F +G + ++++ R GFGFV+F++ +A A+ +
Sbjct: 115 RLIIRNLSFKCSEDDLKTVFAQFGAVLEVNIPRKPDGKMRGFGFVQFKNLLEAGKALKGM 174
Query: 58 DGKELCSERVTIEHARARSR 77
+ KE+ V ++ A A+ +
Sbjct: 175 NMKEIKGRTVAVDWAVAKDK 194
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 69.7 bits (169), Expect = 3e-12
Identities = 68/200 (34%), Positives = 95/200 (47%), Gaps = 27/200 (13%)
Query: 71 HARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQ 130
H+RARSR +G R S R + ++ RT R N S S + R
Sbjct: 311 HSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRS 370
Query: 131 AGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRS 190
+ + HR ++ K SG+ +G K + HSRSRS +
Sbjct: 371 SSK---ERDHRG---------------SSSPRKESGRSQSGSPNK----QRDHSRSRSPN 408
Query: 191 RSRTRSSSRSRSRSRSRSR-KSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSK 249
++R RS SRS ++R RSR +S +++R SRSRS K+R SRS P K++ SRS+
Sbjct: 409 KARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKAR---DHSRSR 465
Query: 250 SPASVDRQRSRSRSRSRSVD 269
SP R RSRSRS S+ D
Sbjct: 466 SPNKA-RDRSRSRSPSKERD 484
Score = 60.1 bits (144), Expect = 2e-09
Identities = 66/203 (32%), Positives = 91/203 (44%), Gaps = 32/203 (15%)
Query: 82 RGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLS---SRVSWQDLKDFMRQAGEVTFAD 138
R R SR PR R + RT +R+ + SR + K + Q G + +
Sbjct: 275 RSRPQSHSQSRSPRRSRSGSQK-RTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSR 333
Query: 139 AHRPKLNEGVVEFASYGDLKNAIEK-LSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSS 197
+H S G +N G+ N + E S HSRS S+ R SS
Sbjct: 334 SH------------SKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSS 381
Query: 198 SRSRSRSRSRS-----RKSYSRSRS------RSRSRSRSKSRSVSRSPVPEKSQKRGSSS 246
S + RS+S ++ +SRSRS RSRSRS K+R SRS P K++ S
Sbjct: 382 SPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKAR---DCS 438
Query: 247 RSKSPASVDRQRSRSRSRSRSVD 269
RS+SP R RSRSRS +++ D
Sbjct: 439 RSRSPYKA-RDRSRSRSPNKARD 460
Score = 56.6 bits (135), Expect = 2e-08
Identities = 63/219 (28%), Positives = 89/219 (40%), Gaps = 31/219 (14%)
Query: 70 EHARARSRG-----GRGRGRYS--DRFSSRRPRNDR---RNAPPVRTENRLIVENLSSRV 119
+H+R+RS R R Y DR SR P R R+ P + +R S
Sbjct: 400 DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDR------SRSR 453
Query: 120 SWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEG 179
S +D R D R + + + G KE + R+ +
Sbjct: 454 SPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGS--------PSKERDHRRSRSPSK 505
Query: 180 SK--RHSRSRSRSRSRTRSSSRSRSRSRSRSRK-SYSRSRSRSRSRSRSKSRSVSRSPVP 236
+ R SRS S+ R RS S S+ R R +SR + R RS+SRS S + SRSP
Sbjct: 506 ERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSK 565
Query: 237 EKSQKRGSS----SRSKSPASVDRQRSRSRSRSRSVDSG 271
E+ ++R S + S +R SRSRS + SG
Sbjct: 566 ERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSG 604
Score = 54.7 bits (130), Expect = 9e-08
Identities = 39/102 (38%), Positives = 55/102 (53%), Gaps = 13/102 (12%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSY---SRSRSRSRSRSRSKSRSVSRSPVP 236
+K RS+SRS S R +SRS S+ R R+ + S+ R R +SRS S+ R SRS P
Sbjct: 540 NKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSP 599
Query: 237 EK---------SQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
K S K + SRS++P S + S+SR+ S+ D
Sbjct: 600 NKQSGYSRPRASSKEKAHSRSRTP-SKEGNHSQSRTSSKESD 640
Score = 51.6 bits (122), Expect = 7e-07
Identities = 37/91 (40%), Positives = 51/91 (56%), Gaps = 3/91 (3%)
Query: 183 HSRSRSRSRSRTRSSSRSRSRSRSRS-RKSYSRSRSRSRSR--SRSKSRSVSRSPVPEKS 239
HS+SRS RSR+ S R+ SR RS S ++++SR+RSR+R S+ S SRS KS
Sbjct: 281 HSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKS 340
Query: 240 QKRGSSSRSKSPASVDRQRSRSRSRSRSVDS 270
Q + + R + R S+ RS S S S
Sbjct: 341 QNQSRTPRRGRSHNWSRNPSKERSHSHSRSS 371
Score = 50.8 bits (120), Expect = 1e-06
Identities = 37/110 (33%), Positives = 56/110 (50%), Gaps = 21/110 (19%)
Query: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRSRK---------SYSRSRSRSRSRSR------- 224
K ++++ +RSR ++ S SRS RSRS S+K S+ R+ SR+RSR+R
Sbjct: 267 KSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQM 326
Query: 225 -----SKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
S+S S +S ++ +RG S S +R S SRS S+ D
Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERD 376
Score = 49.7 bits (117), Expect = 3e-06
Identities = 59/216 (27%), Positives = 92/216 (42%), Gaps = 24/216 (11%)
Query: 56 ELDGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENL 115
E D +L S +H R+RS + R S SS + R+ RR+ P + R
Sbjct: 482 ERDHSQLGSPSKERDHRRSRSPSKERQCRQSR--SSSKERDHRRSRSPSKERQR---RQS 536
Query: 116 SSRVSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIK 175
S +D + E + P + S KE R+ +
Sbjct: 537 RSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRS-----------PSKERERRQSR 585
Query: 176 LIEGSKRHSRSRSRSR----SRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVS 231
+ HSRSRS ++ SR R+SS+ ++ SRSR+ S+ + S+SR+ SK S
Sbjct: 586 SSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTP---SKEGNHSQSRTSSKESDPS 642
Query: 232 RSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
+S VP + S +R+ S S +R S++ S S S
Sbjct: 643 QSTVPRSPDWKRSPTRTSS-LSQNRTPSKTSSHSPS 677
Score = 47.4 bits (111), Expect = 1e-05
Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 5/91 (5%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSRS---RKSYSRSRSRSRSRSRSKSRSVSRSPVP 236
S+ S +++ +RSR +S S+SRS RSRS ++++SR RS S R+ S++RS +R +
Sbjct: 264 SRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGIL 323
Query: 237 EKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
+ R S SRS S Q SR+ R RS
Sbjct: 324 SQ-MGRHSQSRSHSKGKSQNQ-SRTPRRGRS 352
Score = 45.8 bits (107), Expect = 4e-05
Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 15/118 (12%)
Query: 165 SGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKS----------YSR 214
S K K ++ SRSR RS++RT S + +R+ S+ S +SR
Sbjct: 61 SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSR 120
Query: 215 SRSRSRSRSRSKSRSVSRSPVPEKSQKRGS----SSRSKSPASVDR-QRSRSRSRSRS 267
R+ R SRS RS SR+ P + + G+ +SR ++P S + R +S R R+
Sbjct: 121 GRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRT 178
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/81 (44%), Positives = 47/81 (58%), Gaps = 13/81 (16%)
Query: 186 SRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSS 245
SR +S S T SSR KSY+++ +RSR +S S+SRS RS SQKR +
Sbjct: 252 SREKSYSPTEMSSRV---------KSYNQASTRSRPQSHSQSRSPRRSR--SGSQKR-TH 299
Query: 246 SRSKSPASVDRQRSRSRSRSR 266
SR +S S R SR+RSR+R
Sbjct: 300 SRVRSH-SWKRNHSRARSRTR 319
Score = 35.4 bits (80), Expect = 0.053
Identities = 35/109 (32%), Positives = 54/109 (49%), Gaps = 21/109 (19%)
Query: 177 IEGSKRHSRSRSRSRSRTRSSSRS-RSRSRSRSRKSYSRSRSRS-RSRSRSKSRSVSRSP 234
++ +K + +RS ++ +S S S S S+S KS S R+ S R SRS+ RS +R+P
Sbjct: 32 LKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTP 91
Query: 235 VPEKS----------------QKRGSSSRSKSPASVDRQRSRSRSRSRS 267
+ Q+RG+ SR ++P R+ SRS RS S
Sbjct: 92 SRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPG---RRGSRSSKRSPS 137
Score = 35.4 bits (80), Expect = 0.053
Identities = 30/100 (30%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 172 RKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVS 231
R K + S R + SR R+ R SRS S++S SR+ + R R+ ++
Sbjct: 99 RTSKASKASDVRCHQRRGTHSRGRTPGRRGSRS---SKRSPSRASTPGRIRTHGARPGMA 155
Query: 232 RSPVPEKSQKRGSSSRSKS-PASVDRQRSRSRSRSRSVDS 270
SQ++GS +S P + +R+RS S+ R+ S S
Sbjct: 156 SRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKS 195
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 69.3 bits (168), Expect = 3e-12
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 12/92 (13%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
E K + R RSRS TRS SRS S+S SR ++S S+ RSRS +RSRS+ + RS P
Sbjct: 296 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 355
Query: 238 KSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
K RSKS R+R +SRSRS S D
Sbjct: 356 K-------KRSKS-----RERRKSRSRSHSRD 375
Score = 56.6 bits (135), Expect = 2e-08
Identities = 64/281 (22%), Positives = 111/281 (39%), Gaps = 63/281 (22%)
Query: 6 VFIGRLNPAAREKD-VERFFKGYGRIRDIDLKRG------FGFVEFEDPRDADDAVYELD 58
V++G LN D + FFK G ++ + + F FVEF D A+ +
Sbjct: 184 VYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRAL-AFN 242
Query: 59 GKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSR 118
G + I H+ N+ PP ++ +
Sbjct: 243 GVMFGDRPLKINHS-----------------------NNAIVKPP----------EMTPQ 269
Query: 119 VSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
+ ++L++ M++ E + + A + + E+ G+ + + K
Sbjct: 270 AAAKELEEVMKRVREA-----------QSFISAAIEPESGKSNERKGGRSRSHTRSKSRS 318
Query: 179 GSKRHSR---------SRSRSRSRTRSSSRSRSRSRSRSR-KSYSRSRSRSRSRSRSKSR 228
SK HSR SRS +RSR+R R RS+S + R KS R +SRSRS SR K R
Sbjct: 319 SSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK-R 377
Query: 229 SVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
+R + EK + + + +R++ + R +++ D
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 418
Score = 56.6 bits (135), Expect = 2e-08
Identities = 60/225 (26%), Positives = 87/225 (38%), Gaps = 37/225 (16%)
Query: 73 RARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAG 132
R+RS R R R DR S+ P R + E R SR +D ++ +++
Sbjct: 334 RSRSHN-RSRSRQKDRRRSKSPHKKRSKS----RERRKSRSRSHSRDKRKDTREKIKEKE 388
Query: 133 EVTFADAH----RPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRS 188
V D R K E E D EK +E + K + E K H + R
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREK--DREKDKEKDREREREKEHEKDRD 446
Query: 189 RSRSRTRSSSRSRSRSRSR---------------------SRKSYSRSRSRSRSRSRSKS 227
+ + + + + R + RS+ SR+S S SR R R RSRS S
Sbjct: 447 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 506
Query: 228 RSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRS-----RSRSRS 267
RS S ++ R S RS++ R++ R R R RS
Sbjct: 507 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 551
Score = 47.4 bits (111), Expect = 1e-05
Identities = 50/187 (26%), Positives = 76/187 (40%), Gaps = 8/187 (4%)
Query: 71 HARARSRGGRGRGRYSDRFSSR-----RPRNDRRNAPPVRTENRLIVENLSSRVSWQDLK 125
H+R + + R + + +R + R R R R +N+ + K
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 126 DFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSR 185
D R+ + D + K E E D I++ K+ R + R SR
Sbjct: 432 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 491
Query: 186 S--RSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG 243
S R R R R+RSSSRS S++ RKS SRS S + K R R + E+ ++
Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKS-SRSPSPRSRNKKDKKREKERDHISERRERER 550
Query: 244 SSSRSKS 250
S+S KS
Sbjct: 551 STSMRKS 557
Score = 43.5 bits (101), Expect = 2e-04
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 12/118 (10%)
Query: 156 DLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSR-SRTRSSSRSRSRSRSRSRKSYSR 214
D + EK KEI+ ++ K + S+ RS + SR SR+ S R R RS R
Sbjct: 454 DKEKEREKDRSKEIDEKR-KKDKKSRTPPRSYNASRRSRSSSRERRRRRS---------R 503
Query: 215 SRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
S SRS S++ R SRSP P +S+ + R K + +R R RS S S +
Sbjct: 504 SSSRSPRTSKTIKRKSSRSPSP-RSRNKKDKKREKERDHISERRERERSTSMRKSSND 560
Score = 34.7 bits (78), Expect = 0.091
Identities = 36/103 (34%), Positives = 48/103 (46%), Gaps = 17/103 (16%)
Query: 178 EGSKRHSRSRSR--SRSRT--RSSSRSRSRSRSRSRKSYSR-------SRSRSRSRSRSK 226
E +R SRS SR S+T R SSRS S RSR++K R S R R RS S
Sbjct: 496 ERRRRRSRSSSRSPRTSKTIKRKSSRSPS-PRSRNKKDKKREKERDHISERRERERSTSM 554
Query: 227 SRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
+S + EK +K +S + K + + S S+ VD
Sbjct: 555 RKSSNDRDGKEKLEKNSTSLKEK-----EHNKEPDSSVSKEVD 592
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 69.3 bits (168), Expect = 3e-12
Identities = 44/92 (47%), Positives = 54/92 (58%), Gaps = 12/92 (13%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
E K + R RSRS TRS SRS S+S SR ++S S+ RSRS +RSRS+ + RS P
Sbjct: 180 ESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPH 239
Query: 238 KSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
K RSKS R+R +SRSRS S D
Sbjct: 240 K-------KRSKS-----RERRKSRSRSHSRD 259
Score = 56.6 bits (135), Expect = 2e-08
Identities = 64/281 (22%), Positives = 111/281 (39%), Gaps = 63/281 (22%)
Query: 6 VFIGRLNPAAREKD-VERFFKGYGRIRDIDLKRG------FGFVEFEDPRDADDAVYELD 58
V++G LN D + FFK G ++ + + F FVEF D A+ +
Sbjct: 68 VYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRAL-AFN 126
Query: 59 GKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSR 118
G + I H+ N+ PP ++ +
Sbjct: 127 GVMFGDRPLKINHS-----------------------NNAIVKPP----------EMTPQ 153
Query: 119 VSWQDLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIE 178
+ ++L++ M++ E + + A + + E+ G+ + + K
Sbjct: 154 AAAKELEEVMKRVREA-----------QSFISAAIEPESGKSNERKGGRSRSHTRSKSRS 202
Query: 179 GSKRHSR---------SRSRSRSRTRSSSRSRSRSRSRSR-KSYSRSRSRSRSRSRSKSR 228
SK HSR SRS +RSR+R R RS+S + R KS R +SRSRS SR K R
Sbjct: 203 SSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK-R 261
Query: 229 SVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
+R + EK + + + +R++ + R +++ D
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRD 302
Score = 56.6 bits (135), Expect = 2e-08
Identities = 60/225 (26%), Positives = 87/225 (38%), Gaps = 37/225 (16%)
Query: 73 RARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAG 132
R+RS R R R DR S+ P R + E R SR +D ++ +++
Sbjct: 218 RSRSHN-RSRSRQKDRRRSKSPHKKRSKS----RERRKSRSRSHSRDKRKDTREKIKEKE 272
Query: 133 EVTFADAH----RPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRS 188
V D R K E E D EK +E + K + E K H + R
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREK--DREKDKEKDREREREKEHEKDRD 330
Query: 189 RSRSRTRSSSRSRSRSRSR---------------------SRKSYSRSRSRSRSRSRSKS 227
+ + + + + R + RS+ SR+S S SR R R RSRS S
Sbjct: 331 KEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSS 390
Query: 228 RSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRS-----RSRSRS 267
RS S ++ R S RS++ R++ R R R RS
Sbjct: 391 RSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERS 435
Score = 47.4 bits (111), Expect = 1e-05
Identities = 50/187 (26%), Positives = 76/187 (40%), Gaps = 8/187 (4%)
Query: 71 HARARSRGGRGRGRYSDRFSSR-----RPRNDRRNAPPVRTENRLIVENLSSRVSWQDLK 125
H+R + + R + + +R + R R R R +N+ + K
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 126 DFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSR 185
D R+ + D + K E E D I++ K+ R + R SR
Sbjct: 316 DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 375
Query: 186 S--RSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG 243
S R R R R+RSSSRS S++ RKS SRS S + K R R + E+ ++
Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKS-SRSPSPRSRNKKDKKREKERDHISERRERER 434
Query: 244 SSSRSKS 250
S+S KS
Sbjct: 435 STSMRKS 441
Score = 43.5 bits (101), Expect = 2e-04
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 12/118 (10%)
Query: 156 DLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSR-SRTRSSSRSRSRSRSRSRKSYSR 214
D + EK KEI+ ++ K + S+ RS + SR SR+ S R R RS R
Sbjct: 338 DKEKEREKDRSKEIDEKR-KKDKKSRTPPRSYNASRRSRSSSRERRRRRS---------R 387
Query: 215 SRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
S SRS S++ R SRSP P +S+ + R K + +R R RS S S +
Sbjct: 388 SSSRSPRTSKTIKRKSSRSPSP-RSRNKKDKKREKERDHISERRERERSTSMRKSSND 444
Score = 34.7 bits (78), Expect = 0.091
Identities = 36/103 (34%), Positives = 48/103 (46%), Gaps = 17/103 (16%)
Query: 178 EGSKRHSRSRSR--SRSRT--RSSSRSRSRSRSRSRKSYSR-------SRSRSRSRSRSK 226
E +R SRS SR S+T R SSRS S RSR++K R S R R RS S
Sbjct: 380 ERRRRRSRSSSRSPRTSKTIKRKSSRSPS-PRSRNKKDKKREKERDHISERRERERSTSM 438
Query: 227 SRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
+S + EK +K +S + K + + S S+ VD
Sbjct: 439 RKSSNDRDGKEKLEKNSTSLKEK-----EHNKEPDSSVSKEVD 476
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 68.9 bits (167), Expect = 4e-12
Identities = 50/103 (48%), Positives = 60/103 (58%), Gaps = 15/103 (14%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSRSRK----------SYSRSRSR-----SRSRSR 224
S RH+RSRSRS SR+RS SR SRSRSR R+ YSRS +R R RSR
Sbjct: 411 SGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSR 470
Query: 225 SKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
S+S S R + + SSSRS+S S+ RSRS +RSRS
Sbjct: 471 SRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSRSLTRSRS 513
Score = 58.5 bits (140), Expect = 6e-09
Identities = 48/101 (47%), Positives = 53/101 (52%), Gaps = 13/101 (12%)
Query: 180 SKRHSRSRSRSRSRTR-SSSRSRSRSRSRSRK------------SYSRSRSRSRSRSRSK 226
++R S S S S S +R SSSRS SRS SRSR+ S SRS SRSRSRSR
Sbjct: 373 ARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRY 432
Query: 227 SRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
SRS SR R S+SPA R RSRSRS
Sbjct: 433 SRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRS 473
Score = 58.2 bits (139), Expect = 8e-09
Identities = 45/109 (41%), Positives = 57/109 (52%), Gaps = 10/109 (9%)
Query: 166 GKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRS---------RSRSRSRKSYSRSR 216
G+ + R+ S + S SRS +RSSSRSR +RSRSR S+SRSR
Sbjct: 368 GRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSR-SWSRSR 426
Query: 217 SRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
SRSR SRS+SR S + R S S ++ R+RSRSRS S
Sbjct: 427 SRSRRYSRSRSRGRRHSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHS 475
Score = 54.3 bits (129), Expect = 1e-07
Identities = 37/67 (55%), Positives = 46/67 (68%), Gaps = 4/67 (5%)
Query: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEK 238
G + HS SRSRS S + S SRSRS +RSRS +S S S+SRSRSRS+S+S S SP EK
Sbjct: 485 GLRHHSSSRSRS-SWSLSPSRSRSLTRSRS---HSPSPSQSRSRSRSRSQSPSPSPAREK 540
Query: 239 SQKRGSS 245
+ +S
Sbjct: 541 LTRPAAS 547
Score = 40.0 bits (92), Expect = 0.002
Identities = 36/112 (32%), Positives = 49/112 (43%), Gaps = 12/112 (10%)
Query: 137 ADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRS 196
AD ++ G+ + GD + K + + K +E K R RSR + R
Sbjct: 219 ADLNKQATTYGMAD----GDFVRMLRKDKEEAEAIKHAKALEEEKAMYSGR-RSRRQRRE 273
Query: 197 SSRSRSRSRSRSRKSYSRSRS-------RSRSRSRSKSRSVSRSPVPEKSQK 241
R R R S SY+R S RS S S S+SRS SRSP P + +K
Sbjct: 274 FREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEK 325
Score = 39.7 bits (91), Expect = 0.003
Identities = 51/176 (28%), Positives = 76/176 (43%), Gaps = 30/176 (17%)
Query: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKE--INGRKIKLIEGS 180
D +R+ E A H L E E A Y ++ ++ +E + GRKI +
Sbjct: 234 DFVRMLRKDKEEAEAIKHAKALEE---EKAMYSGRRSRRQRREFREKRLRGRKISPPSYA 290
Query: 181 KRHSRSRS---RSRSRTRSSSRSRSRSRSRSRK-------SYSRSRSRSRSRSRSKSRS- 229
+R S + RS S + S SRSRSRS + R+ S+ S + + + + + S
Sbjct: 291 RRDSPTYDPYKRSPSESSSESRSRSRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASG 350
Query: 230 --VSRSPVPEK-----------SQKRGSSSRSKSPAS-VDRQRSRSRSRSRSVDSG 271
+ P P + +++R SSS S S AS RS SRS SRS G
Sbjct: 351 VTTGKPPAPPQPGGPAPGRNASARRRSSSSSSSSSASRTSSSRSSSRSSSRSRRGG 406
Score = 39.7 bits (91), Expect = 0.003
Identities = 52/205 (25%), Positives = 77/205 (37%), Gaps = 15/205 (7%)
Query: 72 ARARSRGG---RGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFM 128
+R+RS G R GR SS R R+ +P + +R + + S S +
Sbjct: 469 SRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSP---SRSRSLTRSRSHSPSPSQSRSRS 525
Query: 129 RQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSK---RHSR 185
R + R KL A LK E +GKE K KL K R +
Sbjct: 526 RSRSQSPSPSPAREKLTRPAASPAVGEKLKKT-EPAAGKETGAAKPKLTPQEKLKLRMQK 584
Query: 186 SRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSS 245
+ +R + +++ + + R+ + R K R E ++
Sbjct: 585 ALNRQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQ 644
Query: 246 SRSKSPA-----SVDRQRSRSRSRS 265
SRS SP S R+RSRSRSRS
Sbjct: 645 SRSPSPRYSREYSSSRRRSRSRSRS 669
Score = 36.6 bits (83), Expect = 0.024
Identities = 47/171 (27%), Positives = 65/171 (38%), Gaps = 13/171 (7%)
Query: 74 ARSRG-GRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAG 132
+RSR R R SR R +P + +S + LK AG
Sbjct: 503 SRSRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAG 562
Query: 133 EVTFADAHRPKLN---------EGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRH 183
+ T A +PKL + + D K A EK+ +E + R+ + E
Sbjct: 563 KET--GAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQE-HERQEREDELRAMA 619
Query: 184 SRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234
+ R + R R R SR +S S SR S SR +SRS SRSP
Sbjct: 620 RKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSP 670
Score = 34.3 bits (77), Expect = 0.12
Identities = 24/60 (40%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 156 DLKNAIEKLSGKEINGRKIKLIEGSKRHSR-SRSRSRSRTRSSSRSRSRSRSRSRKSYSR 214
+L+ K+ KE R+ + E +++SR SRS S +R S SR RSRSRSR + R
Sbjct: 614 ELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRSRSRSRSPHYR 673
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 68.2 bits (165), Expect = 7e-12
Identities = 50/103 (48%), Positives = 60/103 (58%), Gaps = 15/103 (14%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR-----SRSKSRSVSRSP 234
S+ S+S ++SR RTRS S S SRSRSRS S RSRS SRSR SR ++RS S S
Sbjct: 1315 SRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSY 1374
Query: 235 VPEKSQKRGSSSRSKSPA----------SVDRQRSRSRSRSRS 267
KS + S SRS+S + + D SRSRSRSRS
Sbjct: 1375 RSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRS 1417
Score = 63.2 bits (152), Expect = 2e-10
Identities = 45/87 (51%), Positives = 55/87 (63%), Gaps = 2/87 (2%)
Query: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRS-KSRSVSRSPVPEKSQ 240
R S+SRS SR+RS S ++SR R+RS SYS SRSRSRS + S +SRS SRS
Sbjct: 1305 RDDDSQSRSPSRSRSKSETKSRHRTRS-VSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYS 1363
Query: 241 KRGSSSRSKSPASVDRQRSRSRSRSRS 267
+ + SRS S S R+ SRSRSRS
Sbjct: 1364 RGRTRSRSSSYRSYKSHRTSSRSRSRS 1390
Score = 53.1 bits (126), Expect = 2e-07
Identities = 43/95 (45%), Positives = 55/95 (57%), Gaps = 4/95 (4%)
Query: 172 RKIKLIEGSKRHSRSRSRSRSRTRSS-SRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSV 230
RK + R+ S S ++ +R S+SRS SRSRS KS ++SR R+RS S S SRS
Sbjct: 1282 RKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRS-KSETKSRHRTRSVSYSHSRSR 1340
Query: 231 SRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRS 265
SRS S + S SRS+S R R+RSRS S
Sbjct: 1341 SRSST--SSYRSRSYSRSRSRGWYSRGRTRSRSSS 1373
Score = 51.2 bits (121), Expect = 9e-07
Identities = 45/94 (47%), Positives = 51/94 (54%), Gaps = 8/94 (8%)
Query: 181 KRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKS---RSVSRSPVPE 237
+ S SRSRSR SR R+RSRS S +SY R+ SRSRSRS S S SRS +
Sbjct: 1349 RSRSYSRSRSRG---WYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYD 1405
Query: 238 KSQKRGSSSRSKSPASVDRQRSRS-RSRSRSVDS 270
R S SRS+S S R RS RSRS S
Sbjct: 1406 SYYSR-SRSRSRSQRSDSYHRGRSYNRRSRSCRS 1438
Score = 50.1 bits (118), Expect = 2e-06
Identities = 45/86 (52%), Positives = 54/86 (62%), Gaps = 6/86 (6%)
Query: 180 SKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKS 239
S R S S RSRSR SSRSRS SRS +R S S + S SRSRS S SRS SR+ + S
Sbjct: 682 SDRSSESSPRSRSR---SSRSRSYSRSYTR-SRSLASSHSRSRSPS-SRSHSRNKYSDHS 736
Query: 240 QKRGSSSRSKSPASVDRQRSRSRSRS 265
Q SSS + S +S D +R++ R RS
Sbjct: 737 QCSRSSSYT-SISSDDGRRAKRRLRS 761
Score = 50.1 bits (118), Expect = 2e-06
Identities = 37/92 (40%), Positives = 52/92 (56%), Gaps = 10/92 (10%)
Query: 176 LIEGSKRHSRSRSRSRSRTRSSS-RSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234
L + ++ +R R R++ SS ++ SR +S SRSRS+S ++SR ++RSVS S
Sbjct: 1277 LFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYS- 1335
Query: 235 VPEKSQKRGSSSRSKSPASVDRQRSRSRSRSR 266
S SRS+S S R RS SRSRSR
Sbjct: 1336 --------HSRSRSRSSTSSYRSRSYSRSRSR 1359
Score = 49.7 bits (117), Expect = 3e-06
Identities = 37/104 (35%), Positives = 49/104 (47%), Gaps = 3/104 (2%)
Query: 167 KEINGRKIKL---IEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRS 223
K+ R+I + IE SK +R S R RSS S S S++ +S+S +S
Sbjct: 452 KQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSL 511
Query: 224 RSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
SR RS +S RGSS + S RSRS+SRS S
Sbjct: 512 THSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSS 555
Score = 49.7 bits (117), Expect = 3e-06
Identities = 36/95 (37%), Positives = 48/95 (50%), Gaps = 2/95 (2%)
Query: 165 SGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSR 224
S K + K ++ S HS SR RS++ S S SR SRSR+ S S S SRSRS+SR
Sbjct: 495 SSKRDWSKSDKDVQSSLTHS-SRDSYRSKSHSQSYSRGSSRSRTA-SKSSSHSRSRSKSR 552
Query: 225 SKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRS 259
S S+S R + +K S P + R+
Sbjct: 553 SSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRA 587
Score = 47.8 bits (112), Expect = 1e-05
Identities = 49/110 (44%), Positives = 53/110 (48%), Gaps = 27/110 (24%)
Query: 180 SKRHSRSRSR---SRSRTRS-------------SSRSRSRS-----RSRSR-----KSYS 213
S+ +SRSRSR SR RTRS SSRSRSRS SRSR YS
Sbjct: 1350 SRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYS 1409
Query: 214 RSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRS 263
RSRSRSRS+ RS S RS R S S+S S RS S S
Sbjct: 1410 RSRSRSRSQ-RSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSES 1458
Score = 47.0 bits (110), Expect = 2e-05
Identities = 36/89 (40%), Positives = 46/89 (51%), Gaps = 3/89 (3%)
Query: 182 RHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSR---SRSKSRSVSRSPVPEK 238
R SRSRS SRS TRS S + S SRSRS S S SR++ SRS S + S +
Sbjct: 695 RSSRSRSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRR 754
Query: 239 SQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
+++R SS K+ S + S S S
Sbjct: 755 AKRRLRSSGKKNSVSHKKHSSSSEKTLHS 783
Score = 46.6 bits (109), Expect = 2e-05
Identities = 49/206 (23%), Positives = 78/206 (37%), Gaps = 26/206 (12%)
Query: 63 CSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQ 122
CS R RSR G YSD ++R + ++ + +++
Sbjct: 393 CSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKEKKVKHK------------- 439
Query: 123 DLKDFMRQAGEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKR 182
++ + H+ ++ + K++ ++ R + S
Sbjct: 440 ------KKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSH 493
Query: 183 HSRSRSRSRS------RTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVP 236
HS R S+S SSR RS+S S+ SYSR SRSR+ S+S S S SRS
Sbjct: 494 HSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQ-SYSRGSSRSRTASKSSSHSRSRSKSR 552
Query: 237 EKSQKRGSSSRSKSPASVDRQRSRSR 262
S+ SKSP Q S ++
Sbjct: 553 SSSKSGHRKRASKSPRKTASQLSENK 578
Score = 43.1 bits (100), Expect = 3e-04
Identities = 35/79 (44%), Positives = 43/79 (54%), Gaps = 8/79 (10%)
Query: 180 SKRHSRS-----RSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSP 234
S+ SRS SRSRS T S SRSRSRSRS++S S R RS +R +SRS
Sbjct: 1384 SRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRGRSYNR---RSRSCRSYG 1440
Query: 235 VPEKSQKRGSSSRSKSPAS 253
+S + S RS S +S
Sbjct: 1441 SDSESDRSYSHHRSPSESS 1459
Score = 42.7 bits (99), Expect = 3e-04
Identities = 38/99 (38%), Positives = 49/99 (49%), Gaps = 2/99 (2%)
Query: 174 IKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRS 233
IK S + + S S + S+ RS S +S SRS SRSRS SRS +RS S +
Sbjct: 655 IKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRS-SRSRSYSRSYTRSRSLA 713
Query: 234 PVPEKSQKRGSSSRSKSPASVDRQRSRSRS-RSRSVDSG 271
+S+ S S S++ S Q SRS S S S D G
Sbjct: 714 SSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDG 752
Score = 42.7 bits (99), Expect = 3e-04
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 9/99 (9%)
Query: 178 EGSKRHSRSRSRSR-----SRTRSSSRSRSRSRSRSRKSYSRSRSR---SRSRSRSKSRS 229
+G + +S+++ R R ++R R R++ S ++ SR S+SRS S+SRS
Sbjct: 1260 QGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRS 1319
Query: 230 VSRSPVPEKSQKRG-SSSRSKSPASVDRQRSRSRSRSRS 267
S + +++ S SRS+S +S RSRS SRSRS
Sbjct: 1320 KSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRS 1358
Score = 38.9 bits (89), Expect = 0.005
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 5/99 (5%)
Query: 170 NGRKIK--LIEGSKRHS---RSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSR 224
+GR+ K L K++S + S S +T S + R RS + YS SRS S
Sbjct: 751 DGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSD 810
Query: 225 SKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRS 263
S+ SV + ++ +K+G R+ + +R +S+S
Sbjct: 811 SEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKS 849
Score = 38.1 bits (87), Expect = 0.008
Identities = 35/99 (35%), Positives = 46/99 (46%), Gaps = 15/99 (15%)
Query: 180 SKRHSRSRSRSRSRTRS-SSRSRSRSRSRSRKSYSRS------------RSRSRSRSRSK 226
S SRS + S SR+RS SSRS SR++ SRS R++ R RS K
Sbjct: 705 SYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGK 764
Query: 227 SRSVSRSPVPEKSQKRGSSS--RSKSPASVDRQRSRSRS 263
SVS S+K S + + +S R+ S SRS
Sbjct: 765 KNSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRS 803
Score = 37.4 bits (85), Expect = 0.014
Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 19/85 (22%)
Query: 186 SRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSS 245
+R R R + SS S ++ SR S SRS SRSRS+S +KSR +RS
Sbjct: 1285 ARLNRRPRNQESS-SDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRS------------ 1331
Query: 246 SRSKSPASVDRQRSRSRSRSRSVDS 270
S RSRSRS + S S
Sbjct: 1332 ------VSYSHSRSRSRSSTSSYRS 1350
Score = 35.4 bits (80), Expect = 0.053
Identities = 29/56 (51%), Positives = 33/56 (58%), Gaps = 8/56 (14%)
Query: 183 HSRSRSRSRSRTRSSSRSRSRS---RSRSRKSYSRS----RSRSRSRSRSKSRSVS 231
+SRSRSRSRS+ RS S R RS RSRS +SY RS S RS S+S S
Sbjct: 1408 YSRSRSRSRSQ-RSDSYHRGRSYNRRSRSCRSYGSDSESDRSYSHHRSPSESSRYS 1462
Score = 34.3 bits (77), Expect = 0.12
Identities = 39/120 (32%), Positives = 51/120 (42%), Gaps = 11/120 (9%)
Query: 154 YGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYS 213
Y DL A + SG RK K ++ K+ + + R + R S S KS +
Sbjct: 415 YSDLSTA--RHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSST 472
Query: 214 RSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSK------SPASVDRQRSRSRSRSRS 267
R S R RS SRS S S S KR S K + +S D RS+S S+S S
Sbjct: 473 RRMKSSCDRERS-SRSSSLSS--HHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYS 529
Score = 33.9 bits (76), Expect = 0.16
Identities = 34/89 (38%), Positives = 41/89 (46%), Gaps = 19/89 (21%)
Query: 184 SRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRG 243
S S + + S + S+ RS +S RSRSRS SRSRS SRS +RS
Sbjct: 661 SSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRS-SRSRSYSRSYTRS---------- 709
Query: 244 SSSRSKSPASVDRQRSRSRSRSRSVDSGN 272
+S AS SRSRS S S N
Sbjct: 710 -----RSLAS---SHSRSRSPSSRSHSRN 730
Score = 33.1 bits (74), Expect = 0.27
Identities = 26/82 (31%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Query: 184 SRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQK-R 242
S S S S S + SSS S R+ + R RS+ R K S S P + + +
Sbjct: 198 SDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPK 257
Query: 243 GSSSRS--KSPASVDRQRSRSR 262
G S RS SVD R +
Sbjct: 258 GHSERSDTNEKRSVDSSAKREK 279
Score = 32.3 bits (72), Expect = 0.45
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 1/87 (1%)
Query: 185 RSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGS 244
+ R + S S S S S S S RSR R + V RS K
Sbjct: 187 KKRKKPTHSEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASSSE 246
Query: 245 SSRSKSPASVDRQRSRS-RSRSRSVDS 270
R+K + RS + RSVDS
Sbjct: 247 EPRNKHAMNPKGHSERSDTNEKRSVDS 273
Score = 31.6 bits (70), Expect = 0.77
Identities = 40/188 (21%), Positives = 75/188 (39%), Gaps = 13/188 (6%)
Query: 84 RYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPK 143
+YSDR S PR+ R++ R+ +R + S S + ++ H
Sbjct: 680 KYSDRSSESSPRSRSRSSRS-RSYSRSYTRSRSLASSHSRSRSPSSRSHSRNKYSDHSQC 738
Query: 144 LNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRS------RSRTRSS 197
S D + A +L +G+K + K+HS S ++ + R RSS
Sbjct: 739 SRSSSYTSISSDDGRRAKRRLRS---SGKKNSV--SHKKHSSSSEKTLHSKYVKGRDRSS 793
Query: 198 SRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQ 257
R S SRS YS +S ++ ++ + E++ + +R + + +R+
Sbjct: 794 C-VRKYSESRSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERE 852
Query: 258 RSRSRSRS 265
S+ R+
Sbjct: 853 CPHSKKRT 860
Score = 30.4 bits (67), Expect = 1.7
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 210 KSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRSVD 269
K S S + S+S + S ++S + SS RS+S +S R SRS +RSRS+
Sbjct: 656 KETGSSSSYHKREKNSESDQSTYSKYSDRSSE--SSPRSRSRSSRSRSYSRSYTRSRSLA 713
Query: 270 SGN 272
S +
Sbjct: 714 SSH 716
Score = 30.0 bits (66), Expect = 2.2
Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 5/72 (6%)
Query: 178 EGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPE 237
E H RSR R R RS+ R + S R++ + S+ RS E
Sbjct: 213 ESELEHERSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSE-----RSDTNE 267
Query: 238 KSQKRGSSSRSK 249
K S+ R K
Sbjct: 268 KRSVDSSAKREK 279
>gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens]
Length = 288
Score = 67.4 bits (163), Expect = 1e-11
Identities = 51/118 (43%), Positives = 65/118 (55%), Gaps = 20/118 (16%)
Query: 153 SYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRS---RTRSSSRSRSRSRSRSR 209
+YG+ ++ SG K S RH+ +RSRS+ R+RS SRSRS SRSRSR
Sbjct: 8 NYGERESRSASRSGSAHGSGK------SARHTPARSRSKEDSRRSRSKSRSRSESRSRSR 61
Query: 210 KS----YSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRS 263
+S Y+RSRSRSRS RS+SRS SR R S S SP S R+ +R+
Sbjct: 62 RSSRRHYTRSRSRSRSHRRSRSRSYSR-------DYRRRHSHSHSPMSTRRRHVGNRA 112
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 24/88 (27%)
Query: 181 KRHSRSRSRSRSRTRSSSRSR-SRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKS 239
+R SRS SRS S S +R + +RSRS++ RSRS+SRSRS S+SRS
Sbjct: 11 ERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRS---------- 60
Query: 240 QKRGSSSRSKSPASVDRQRSRSRSRSRS 267
R SS +R +RSRSRS
Sbjct: 61 --RRSS-----------RRHYTRSRSRS 75
Score = 40.0 bits (92), Expect = 0.002
Identities = 29/103 (28%), Positives = 46/103 (44%), Gaps = 10/103 (9%)
Query: 4 CRVFIGRLNPAAREKDVERFFKGYGRIRDIDL--------KRGFGFVEFEDPRDADDAVY 55
C + + L+ E+D+ F YG I D+ + RGF FV FE+ DA +A
Sbjct: 118 CCLGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKE 177
Query: 56 ELDGKELCSERVTIEHARARSRGGRGRGRYSDR--FSSRRPRN 96
+G EL R+ ++ + + G Y R + S R R+
Sbjct: 178 RANGMELDGRRIRVDFSITKRPHTPTPGIYMGRPTYGSSRRRD 220
Score = 36.2 bits (82), Expect = 0.031
Identities = 34/93 (36%), Positives = 44/93 (47%), Gaps = 24/93 (25%)
Query: 179 GSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEK 238
G + + SRS SR+ S+ S +R +S S+ SR RSRSKSR
Sbjct: 5 GEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSR---RSRSKSR---------- 51
Query: 239 SQKRGSSSRSKSPA----SVDRQRSRSRSRSRS 267
SRS+S + S R +RSRSRSRS
Sbjct: 52 -------SRSESRSRSRRSSRRHYTRSRSRSRS 77
Score = 34.7 bits (78), Expect = 0.091
Identities = 21/53 (39%), Positives = 30/53 (56%)
Query: 215 SRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
S S ++ +SRS SRS S K + ++S + D +RSRS+SRSRS
Sbjct: 2 SDSGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRS 54
Score = 33.5 bits (75), Expect = 0.20
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 211 SYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSRS 267
S S ++ SRS SRS S + ++ + SRSK + R +SRSRS SRS
Sbjct: 2 SDSGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRS 58
>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
Length = 524
Score = 67.0 bits (162), Expect = 2e-11
Identities = 48/118 (40%), Positives = 63/118 (53%), Gaps = 5/118 (4%)
Query: 152 ASYGDLKNAIEKLSGKEINGRKIKLIEG-SKRHSRSRSRSRSRTRSSSRSRSRSRSRSRK 210
A Y +N + +G E +K K + S+ H R RS+S+ R RS R R +S+SR RK
Sbjct: 13 APYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERK 72
Query: 211 SYSRSRSRSRSRSRSKSRSV-SRSPVPEKSQKRGSSSRSK--SPASVDRQRSRSRSRS 265
SRS+ R RSRSRS+ R R P K S+ R K P S+ R RSRS+S
Sbjct: 73 R-SRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRSRSKS 129
Score = 54.3 bits (129), Expect = 1e-07
Identities = 38/111 (34%), Positives = 56/111 (50%), Gaps = 27/111 (24%)
Query: 156 DLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSRSRTRSSSRSRSRSRSRSRKSYSRS 215
D++ +E K+ N K+ G + S+ R +S+SR+RS R RS+S+ R R SR
Sbjct: 6 DIEAMLEAPYKKDEN--KLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKR---SRD 60
Query: 216 RSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRSKSPASVDRQRSRSRSRSR 266
R R +S+SR + RS S+ +R+RSRSRSR R
Sbjct: 61 RERKKSKSRERKRSRSK----------------------ERRRSRSRSRDR 89
Score = 42.7 bits (99), Expect = 3e-04
Identities = 45/199 (22%), Positives = 86/199 (43%), Gaps = 30/199 (15%)
Query: 6 VFIGRLNPAAREKDVERFFKGYGRIRDIDL--------KRGFGFVEFEDPRDADDAVYEL 57
VF +L R +D+E FF G++RD+ + +G +VEF D A+ L
Sbjct: 155 VFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAI-GL 213
Query: 58 DGKELCSERVTIEHARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSS 117
G+ + + ++ ++A +R ++ + +A P+ RL V +L
Sbjct: 214 TGQRVLGVPIIVQASQAE----------KNRAAAMANNLQKGSAGPM----RLYVGSLHF 259
Query: 118 RVSWQDLKDFMRQAGEVTF------ADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEING 171
++ L+ G + ++ R K G + F+ K A+E+L+G E+ G
Sbjct: 260 NITEDMLRGIFEPFGRIESIQLMMDSETGRSK-GYGFITFSDSECAKKALEQLNGFELAG 318
Query: 172 RKIKLIEGSKRHSRSRSRS 190
R +K+ ++R S + S
Sbjct: 319 RPMKVGHVTERTDASSASS 337
Score = 40.8 bits (94), Expect = 0.001
Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 5 RVFIGRLNPAAREKDVERFFKGYGRIRDIDL--------KRGFGFVEFEDPRDADDAVYE 56
R+++G L+ E + F+ +GRI I L +G+GF+ F D A A+ +
Sbjct: 251 RLYVGSLHFNITEDMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQ 310
Query: 57 LDGKELCSERVTIEHARARS 76
L+G EL + + H R+
Sbjct: 311 LNGFELAGRPMKVGHVTERT 330
Score = 36.6 bits (83), Expect = 0.024
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 21/79 (26%)
Query: 189 RSRSRTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQKRGSSSRS 248
+ ++ S++ RS+ R +KS SRSRS R RS+SK R SR
Sbjct: 17 KDENKLSSANGHEERSKKR-KKSKSRSRSHERKRSKSKERKRSRDR-------------- 61
Query: 249 KSPASVDRQRSRSRSRSRS 267
+R++S+SR R RS
Sbjct: 62 ------ERKKSKSRERKRS 74
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.354
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,402,033
Number of Sequences: 37866
Number of extensions: 415255
Number of successful extensions: 15337
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 434
Number of HSP's successfully gapped in prelim test: 313
Number of HSP's that attempted gapping in prelim test: 3584
Number of HSP's gapped (non-prelim): 3944
length of query: 272
length of database: 18,247,518
effective HSP length: 101
effective length of query: 171
effective length of database: 14,423,052
effective search space: 2466341892
effective search space used: 2466341892
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.