Search of human proteins with 86792455

Search of human proteins with 86792455

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|86792455 aquaporin 6 [Homo sapiens]
         (282 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|86792455 aquaporin 6 [Homo sapiens]                                553   e-158
gi|4502179 aquaporin 2 [Homo sapiens]                                 299   2e-81
gi|4502183 aquaporin 5 [Homo sapiens]                                 286   1e-77
gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]       254   5e-68
gi|37694062 aquaporin 1 [Homo sapiens]                                202   2e-52
gi|4755125 aquaporin 4 isoform b [Homo sapiens]                       196   3e-50
gi|4502181 aquaporin 4 isoform a [Homo sapiens]                       196   3e-50
gi|45446752 aquaporin 8 [Homo sapiens]                                108   7e-24
gi|157266307 aquaporin 9 [Homo sapiens]                                93   2e-19
gi|4502187 aquaporin 7 [Homo sapiens]                                  80   2e-15
gi|4826645 aquaporin 3 [Homo sapiens]                                  69   4e-12
gi|22538420 aquaporin 10 [Homo sapiens]                                54   2e-07
gi|40538880 aquaporin 12A [Homo sapiens]                               40   0.003
gi|156447037 aquaporin 12B [Homo sapiens]                              37   0.019
gi|51702206 solute carrier family 41 member 1 [Homo sapiens]           33   0.37 
gi|216547942 solute carrier family 35, member B3 [Homo sapiens]        29   5.3  
gi|216547920 solute carrier family 35, member B3 [Homo sapiens]        29   5.3  
gi|21361503 solute carrier family 35, member B3 [Homo sapiens]         29   5.3  
gi|166064062 tumor suppressing subtransferable candidate 5 [Homo...    28   9.0  
gi|166064060 tumor suppressing subtransferable candidate 5 [Homo...    28   9.0  

>gi|86792455 aquaporin 6 [Homo sapiens]
          Length = 282

 Score =  553 bits (1424), Expect = e-158
 Identities = 282/282 (100%), Positives = 282/282 (100%)

Query: 1   MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI 60
           MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI
Sbjct: 1   MDAVEPGGRGWASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAI 60

Query: 61  TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG 120
           TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG
Sbjct: 61  TFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYG 120

Query: 121 VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISV 180
           VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISV
Sbjct: 121 VMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISV 180

Query: 181 ALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTK 240
           ALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTK
Sbjct: 181 ALGHLIGIHFTGCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTK 240

Query: 241 TLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV 282
           TLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV
Sbjct: 241 TLAQRLAILTGTVEVGTGAGAGAEPLKKESQPGSGAVEMESV 282


>gi|4502179 aquaporin 2 [Homo sapiens]
          Length = 271

 Score =  299 bits (765), Expect = 2e-81
 Identities = 148/232 (63%), Positives = 178/232 (76%), Gaps = 2/232 (0%)

Query: 22  AISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHA 81
           A SRA+FAEFLAT L+VFFG+GS + WP ALPSVLQIA+ F L     VQ     SGAH 
Sbjct: 8   AFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHI 67

Query: 82  NPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVST 141
           NPAVT+A LVG H+S+ RA  YVAAQL+GA  GAALL+ + P DIR  L +N + NS + 
Sbjct: 68  NPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTA 127

Query: 142 GQAVAVELLLTLQLVLCVFASTDSR--QTSGSPATMIGISVALGHLIGIHFTGCSMNPAR 199
           GQAV VEL LTLQLVLC+FASTD R  +  G+PA  IG SVALGHL+GIH+TGCSMNPAR
Sbjct: 128 GQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPAR 187

Query: 200 SFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTG 251
           S  PA++ GKF  HWVFW+GPL+GA+L SL+YN+VLFP  K+L++RLA+L G
Sbjct: 188 SLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKG 239


>gi|4502183 aquaporin 5 [Homo sapiens]
          Length = 265

 Score =  286 bits (733), Expect = 1e-77
 Identities = 138/236 (58%), Positives = 184/236 (77%), Gaps = 3/236 (1%)

Query: 22  AISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHA 81
           A  +A+FAEFLAT ++VFFG+GS ++WP+ALP++LQIA+ F L      Q     SG H 
Sbjct: 9   AFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPVSGGHI 68

Query: 82  NPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVST 141
           NPA+TLA LVG+ ISL RA  YVAAQLVGA  GA +LYGV P + R  L +N + N+ + 
Sbjct: 69  NPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALNNNTTQ 128

Query: 142 GQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGISVALGHLIGIHFTGCSMNPAR 199
           GQA+ VEL+LT QL LC+FASTDSR+TS  GSPA  IG+SV LGHL+GI+FTGCSMNPAR
Sbjct: 129 GQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCSMNPAR 188

Query: 200 SFGPAIIIGKFT-VHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTGTVE 254
           SFGPA+++ +F+  HWVFWVGP++GA+LA+++Y ++LFP++ +L++R+AI+ GT E
Sbjct: 189 SFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTYE 244


>gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]
          Length = 263

 Score =  254 bits (650), Expect = 5e-68
 Identities = 127/229 (55%), Positives = 162/229 (70%), Gaps = 2/229 (0%)

Query: 25  RALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHANPA 84
           RA+FAEF AT  YVFFG+GS +RW      VLQ+A+ F L  A  VQ     SGAH NPA
Sbjct: 11  RAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAMAFGLALATLVQSVGHISGAHVNPA 70

Query: 85  VTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVSTGQA 144
           VT AFLVGS +SL RA  Y+AAQL+GA  GAA+LY V P  +R  L +N +  +VS GQA
Sbjct: 71  VTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLALNTLHPAVSVGQA 130

Query: 145 VAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGISVALGHLIGIHFTGCSMNPARSFG 202
             VE+ LTLQ VLC+FA+ D R+    GS A  +G S+ALGHL G+++TG  MNPARSF 
Sbjct: 131 TTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTGAGMNPARSFA 190

Query: 203 PAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTG 251
           PAI+ G FT HWV+WVGP++G  L SL+Y+F+LFP  K++++RL++L G
Sbjct: 191 PAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKG 239


>gi|37694062 aquaporin 1 [Homo sapiens]
          Length = 269

 Score =  202 bits (515), Expect = 2e-52
 Identities = 112/244 (45%), Positives = 154/244 (63%), Gaps = 10/244 (4%)

Query: 21  KAISRALFAEFLATGLYVFFGVGSVM--RWP-----TALPSVLQIAITFNLVTAMAVQVT 73
           K   RA+ AEFLAT L+VF  +GS +  ++P     TA+   +++++ F L  A   Q  
Sbjct: 8   KLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLAQSV 67

Query: 74  WKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGIN 133
              SGAH NPAVTL  L+   IS+ RA+ Y+ AQ VGA V  A+L G+       +LG N
Sbjct: 68  GHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRN 127

Query: 134 VVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTS--GSPATMIGISVALGHLIGIHFT 191
            + + V++GQ + +E++ TLQLVLCV A+TD R+    GS    IG+SVALGHL+ I +T
Sbjct: 128 DLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYT 187

Query: 192 GCSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILT- 250
           GC +NPARSFG A+I   F+ HW+FWVGP +G  LA LIY+F+L P +  L  R+ + T 
Sbjct: 188 GCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTS 247

Query: 251 GTVE 254
           G VE
Sbjct: 248 GQVE 251


>gi|4755125 aquaporin 4 isoform b [Homo sapiens]
          Length = 301

 Score =  196 bits (497), Expect = 3e-50
 Identities = 103/228 (45%), Positives = 148/228 (64%), Gaps = 12/228 (5%)

Query: 20  WKAISRALFAEFLATGLYVFFGVGSVMRW-----PTALPSVLQIAITFNLVTAMAVQVTW 74
           WKA++    AEFLA  ++V   +GS + W     P  +  VL I++ F L  A  VQ   
Sbjct: 13  WKAVT----AEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVL-ISLCFGLSIATMVQCFG 67

Query: 75  KASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINV 134
             SG H NPAVT+A +    IS+ ++V Y+AAQ +GA +GA +LY V P  +   LG+ +
Sbjct: 68  HISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTM 127

Query: 135 VRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQT--SGSPATMIGISVALGHLIGIHFTG 192
           V  +++ G  + VEL++T QLV  +FAS DS++T  +GS A  IG SVA+GHL  I++TG
Sbjct: 128 VHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTG 187

Query: 193 CSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTK 240
            SMNPARSFGPA+I+G +  HW++WVGP++GA+LA  +Y +V  PD +
Sbjct: 188 ASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVE 235


>gi|4502181 aquaporin 4 isoform a [Homo sapiens]
          Length = 323

 Score =  196 bits (497), Expect = 3e-50
 Identities = 103/228 (45%), Positives = 148/228 (64%), Gaps = 12/228 (5%)

Query: 20  WKAISRALFAEFLATGLYVFFGVGSVMRW-----PTALPSVLQIAITFNLVTAMAVQVTW 74
           WKA++    AEFLA  ++V   +GS + W     P  +  VL I++ F L  A  VQ   
Sbjct: 35  WKAVT----AEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVL-ISLCFGLSIATMVQCFG 89

Query: 75  KASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINV 134
             SG H NPAVT+A +    IS+ ++V Y+AAQ +GA +GA +LY V P  +   LG+ +
Sbjct: 90  HISGGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTM 149

Query: 135 VRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQT--SGSPATMIGISVALGHLIGIHFTG 192
           V  +++ G  + VEL++T QLV  +FAS DS++T  +GS A  IG SVA+GHL  I++TG
Sbjct: 150 VHGNLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTG 209

Query: 193 CSMNPARSFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTK 240
            SMNPARSFGPA+I+G +  HW++WVGP++GA+LA  +Y +V  PD +
Sbjct: 210 ASMNPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCPDVE 257


>gi|45446752 aquaporin 8 [Homo sapiens]
          Length = 261

 Score =  108 bits (269), Expect = 7e-24
 Identities = 67/205 (32%), Positives = 103/205 (50%), Gaps = 5/205 (2%)

Query: 30  EFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHANPAVTLAF 89
           E L + L++F G  SV+   T    +LQ A+   L   + +      SG H NPAV+LA 
Sbjct: 41  ELLGSALFIFIGCLSVIENGTDT-GLLQPALAHGLALGLVIATLGNISGGHFNPAVSLAA 99

Query: 90  LVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDI---RETLGINVVRNSVSTGQAVA 146
           ++   ++L   + Y  +QL+G  +GAAL   V P +            V+       A+ 
Sbjct: 100 MLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQGQVAGALV 159

Query: 147 VELLLTLQLVLCVFASTDSRQTSGSPATM-IGISVALGHLIGIHFTGCSMNPARSFGPAI 205
            E++LT  L L V     + +T G  A   IG +V +  L G   +G  MNPAR+FGPA+
Sbjct: 160 AEIILTTLLALAVCMGAINEKTKGPLAPFSIGFAVTVDILAGGPVSGGCMNPARAFGPAV 219

Query: 206 IIGKFTVHWVFWVGPLMGALLASLI 230
           +   +  HW++W+GPL+  LL  L+
Sbjct: 220 VANHWNFHWIYWLGPLLAGLLVGLL 244


>gi|157266307 aquaporin 9 [Homo sapiens]
          Length = 295

 Score = 93.2 bits (230), Expect = 2e-19
 Identities = 75/251 (29%), Positives = 122/251 (48%), Gaps = 36/251 (14%)

Query: 19  LWKAISRALFAEFLATGLYVFFGVGSVMRWPTA---LPSVLQIAITFNLVTAMAVQVTWK 75
           L  ++++   +EFL T + +  G G V +   +      V+ I + F++  AMA+ V   
Sbjct: 18  LKSSLAKETLSEFLGTFILIVLGCGCVAQAILSRGRFGGVITINVGFSMAVAMAIYVAGG 77

Query: 76  ASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLG---I 132
            SG H NPAV+LA  +   +   +   YV AQ +GA VGAA ++G+    +    G   +
Sbjct: 78  VSGGHINPAVSLAMCLFGRMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKLL 137

Query: 133 NVVRNS------------VSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATMIGISV 180
            V  N+            +S   A A +++ T+ L++ VFA  DSR   G+P  +  I++
Sbjct: 138 IVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNL-GAPRGLEPIAI 196

Query: 181 AL-----GHLIGIHFTGCSMNPARSFGPAIIIG----KFTVH-------WVFWVGPLMGA 224
            L        +G++ +GC+MNPAR   P +        F V        W+  VGPL+GA
Sbjct: 197 GLLIIVIASSLGLN-SGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGA 255

Query: 225 LLASLIYNFVL 235
           ++  LIY  V+
Sbjct: 256 VIGGLIYVLVI 266


>gi|4502187 aquaporin 7 [Homo sapiens]
          Length = 342

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 77/245 (31%), Positives = 107/245 (43%), Gaps = 33/245 (13%)

Query: 19  LWKAISRALFAEFLATGLYVFFGVGSV--MRWPTALPSVLQIAITFNLVTAMAVQVTWKA 76
           L + + R   AEF++T + + FG+GSV  M       S L + + F     M V V  + 
Sbjct: 29  LQRKMVREFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRI 88

Query: 77  SGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGIN-VV 135
           SGAH N AVT A      +   +   YV  Q +G+ + AA +Y +    I    G   +V
Sbjct: 89  SGAHMNAAVTFANCALGRVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMV 148

Query: 136 RNSVSTGQAVAV--------------ELLLTLQLVLCVFASTDSRQTSGSPAT---MIGI 178
              V+T    A               E  LT  L LC+FA TD       P T   +IGI
Sbjct: 149 TGPVATAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGI 208

Query: 179 SVA-LGHLIGIHFTGCSMNPARSFGPAIII-----GKFTVH------WVFWVGPLMGALL 226
            V  +G  +G++ TG ++NP+R   P I       GK          WV  V PL+GA L
Sbjct: 209 LVVIIGVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYL 267

Query: 227 ASLIY 231
             +IY
Sbjct: 268 GGIIY 272


>gi|4826645 aquaporin 3 [Homo sapiens]
          Length = 292

 Score = 69.3 bits (168), Expect = 4e-12
 Identities = 66/245 (26%), Positives = 107/245 (43%), Gaps = 36/245 (14%)

Query: 25  RALFAEFLATGLYVFFGVGSVMRWPTALPS---VLQIAITFNLVTAMAVQVTWKASGAHA 81
           R   AE L T + V FG GSV +   +  +    L I + F     + + +  + SGAH 
Sbjct: 23  RQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHL 82

Query: 82  NPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRE-------TLGINV 134
           NPAVT A    +     +   Y  AQ +GA +GA +++G+    I           G N 
Sbjct: 83  NPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLYYDAIWHFADNQLFVSGPNG 142

Query: 135 VRNSVSTGQAVAVELLL--------TLQLVLCVFASTDSRQTS---GSPATMIGISV-AL 182
                +T  +  ++++         T  L++CV A  D        G  A  +G+ V  +
Sbjct: 143 TAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLVI 202

Query: 183 GHLIGIHFTGCSMNPARSFGPAIII-------GKFTV--HWVFW---VGPLMGALLASLI 230
           G  +G + +G ++NPAR FGP +           FT   HW +W   V PL+G++    +
Sbjct: 203 GTSMGFN-SGYAVNPARDFGPRLFTALAGWGSAVFTTGQHW-WWVPIVSPLLGSIAGVFV 260

Query: 231 YNFVL 235
           Y  ++
Sbjct: 261 YQLMI 265


>gi|22538420 aquaporin 10 [Homo sapiens]
          Length = 301

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 60/256 (23%), Positives = 105/256 (41%), Gaps = 44/256 (17%)

Query: 18  RLWKAISRALFAEFLATGLYVFFGVGSVMRWPTA---LPSVLQIAITFNLVTAMAVQVTW 74
           R+   ++R   AEFL   + +    G+V +  T+     +   + +  +L   +A+ V  
Sbjct: 15  RIRSLLARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGG 74

Query: 75  KASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINV 134
             SGAH NPA +LA  +   +   +   Y+  QL+ A   +   Y +    ++   G N+
Sbjct: 75  NVSGAHLNPAFSLAMCIVGRLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGNL 134

Query: 135 VRNS---------------VSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPA----TM 175
                              +S       ++L T  L++ + A  D R+  G PA     +
Sbjct: 135 TVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILD-RRNKGVPAGLEPVV 193

Query: 176 IGISV-ALGHLIGIHFTGCSMNPARSFGPAIIIGKFTV---------------HWVFWVG 219
           +G+ + ALG  +G +  G  +NPAR  GP +    FT                 WV  V 
Sbjct: 194 VGMLILALGLSMGAN-CGIPLNPARDLGPRL----FTYVAGWGPEVFSAGNGWWWVPVVA 248

Query: 220 PLMGALLASLIYNFVL 235
           PL+GA + +  Y  ++
Sbjct: 249 PLVGATVGTATYQLLV 264


>gi|40538880 aquaporin 12A [Homo sapiens]
          Length = 295

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 58/243 (23%), Positives = 90/243 (37%), Gaps = 38/243 (15%)

Query: 11  WASMLACRLWKAISRALFAEFLATGLYVFFGVGSVMR------WPTALPSVLQIAITFNL 64
           +A+   C   +  S+AL    L  G Y  F   ++        W       L + + F L
Sbjct: 12  FATFALCEAARRASKAL----LPVGAYEVFAREAMRTLVELGPWAGDFGPDLLLTLLFLL 67

Query: 65  VTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPG 124
             A  V +     GA ANP V+L   + +  SLP  +  +AAQ +G      L+      
Sbjct: 68  FLAHGVTL----DGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAW 123

Query: 125 DIRETLGI---------NVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSRQTSGSPATM 175
           ++ +   +         + +R SV  G  V         L L             SP   
Sbjct: 124 ELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLL--------HLRHSPPAY 175

Query: 176 IGISVALGHLIGIH----FTGCSMNPARSFGPAIIIGKFTV---HWVFWVGPLMGALLAS 228
            G +VAL   +  +    FT    NPA +          T+     V+W+GPL G +LA 
Sbjct: 176 SGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGMVLAV 235

Query: 229 LIY 231
           L++
Sbjct: 236 LLH 238


>gi|156447037 aquaporin 12B [Homo sapiens]
          Length = 307

 Score = 37.0 bits (84), Expect = 0.019
 Identities = 48/192 (25%), Positives = 73/192 (38%), Gaps = 28/192 (14%)

Query: 56  LQIAITFNLVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGA 115
           L + + F L  A  V +     GA ANP V+L   + +  SLP  +  +AAQ +G     
Sbjct: 71  LLLTLLFLLFLAHGVTL----DGASANPTVSLQEFLMAEESLPGTLLKLAAQGLGMQAAC 126

Query: 116 ALLYGVMPGDIRETLGI---------NVVRNSVSTGQAVAVELLLTLQLVLCVFASTDSR 166
            L       ++ +   +         + +R SV  G  V         L L         
Sbjct: 127 TLTRLCWAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLL-------- 178

Query: 167 QTSGSPATMIGISVALGHLIGIH----FTGCSMNPARSFGPAIIIGKFTV---HWVFWVG 219
               SP    G +VAL   +  +    FT    NPA +          T+     V+W+G
Sbjct: 179 HLRHSPPAYSGPAVALLVTVTAYTAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLG 238

Query: 220 PLMGALLASLIY 231
           PL G +LA L++
Sbjct: 239 PLTGMVLAVLLH 250


>gi|51702206 solute carrier family 41 member 1 [Homo sapiens]
          Length = 513

 Score = 32.7 bits (73), Expect = 0.37
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 6/106 (5%)

Query: 53  PSVLQIAITFN--LVTAMAVQVTWKASGAHANPAVTLAFLVGSHISLPRAVAYVAAQLVG 110
           P  L   IT N  L+   A  V + AS A    AV   ++   H S+P A    A+ +  
Sbjct: 169 PKELWRMITGNMALIQVQATVVGFLASIA----AVVFGWIPDGHFSIPHAFLLCASSVAT 224

Query: 111 ATVGAALLYGVMPGDIRETLGINVVRNSVSTGQAVAVELLLTLQLV 156
           A + + +L  +M G I  +  I +  ++V+T  A ++  L+TL L+
Sbjct: 225 AFIASLVLGMIMIGVIIGSRKIGINPDNVATPIAASLGDLITLALL 270


>gi|216547942 solute carrier family 35, member B3 [Homo sapiens]
          Length = 401

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 5/56 (8%)

Query: 175 MIGISVALGHLIGIHFTGCSMNPARSFGPAIII---GKFTVHWVFWVGPLMGALLA 227
           ++G++   G  +G   T C+ NP R++G A +    G F + +V  +  + GAL+A
Sbjct: 273 LLGLTCTSG--LGPAVTFCAKNPVRTYGYAFLFSLTGYFGISFVLALIKIFGALIA 326


>gi|216547920 solute carrier family 35, member B3 [Homo sapiens]
          Length = 401

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 5/56 (8%)

Query: 175 MIGISVALGHLIGIHFTGCSMNPARSFGPAIII---GKFTVHWVFWVGPLMGALLA 227
           ++G++   G  +G   T C+ NP R++G A +    G F + +V  +  + GAL+A
Sbjct: 273 LLGLTCTSG--LGPAVTFCAKNPVRTYGYAFLFSLTGYFGISFVLALIKIFGALIA 326


>gi|21361503 solute carrier family 35, member B3 [Homo sapiens]
          Length = 401

 Score = 28.9 bits (63), Expect = 5.3
 Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 5/56 (8%)

Query: 175 MIGISVALGHLIGIHFTGCSMNPARSFGPAIII---GKFTVHWVFWVGPLMGALLA 227
           ++G++   G  +G   T C+ NP R++G A +    G F + +V  +  + GAL+A
Sbjct: 273 LLGLTCTSG--LGPAVTFCAKNPVRTYGYAFLFSLTGYFGISFVLALIKIFGALIA 326


>gi|166064062 tumor suppressing subtransferable candidate 5 [Homo
           sapiens]
          Length = 424

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 24/166 (14%)

Query: 23  ISRALFAEFLATG-LYVFFGVGSVMRWPT----ALPSVLQIAITFNLVTAMAVQVTWKAS 77
           +SR L  + +A G L   FGV  ++  P     A     + A+T + + A+A+ +   A+
Sbjct: 50  LSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAA 109

Query: 78  GAHANPAVTLAFLVGSHISLPRAVAYV--AAQLVGATVGAALLYGVMPGDIRETLGINVV 135
            + A P V L F       LP A+ +   AAQ+V   + A        G +    G+ V+
Sbjct: 110 SSPALPGVYLLFA----SRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVI 165

Query: 136 RNSVSTGQAVAV------ELLLTLQLVL-------CVFASTDSRQT 168
             S+  G  V+        +L  L  +L       C+ AST   +T
Sbjct: 166 LGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAKT 211


>gi|166064060 tumor suppressing subtransferable candidate 5 [Homo
           sapiens]
          Length = 424

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 43/166 (25%), Positives = 70/166 (42%), Gaps = 24/166 (14%)

Query: 23  ISRALFAEFLATG-LYVFFGVGSVMRWPT----ALPSVLQIAITFNLVTAMAVQVTWKAS 77
           +SR L  + +A G L   FGV  ++  P     A     + A+T + + A+A+ +   A+
Sbjct: 50  LSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAA 109

Query: 78  GAHANPAVTLAFLVGSHISLPRAVAYV--AAQLVGATVGAALLYGVMPGDIRETLGINVV 135
            + A P V L F       LP A+ +   AAQ+V   + A        G +    G+ V+
Sbjct: 110 SSPALPGVYLLFA----SRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVI 165

Query: 136 RNSVSTGQAVAV------ELLLTLQLVL-------CVFASTDSRQT 168
             S+  G  V+        +L  L  +L       C+ AST   +T
Sbjct: 166 LGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAKT 211


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.136    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,868,769
Number of Sequences: 37866
Number of extensions: 385478
Number of successful extensions: 933
Number of sequences better than 10.0: 20
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 893
Number of HSP's gapped (non-prelim): 23
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.