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Search of human proteins with 83716024
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83716024 kinesin family member 21B [Homo sapiens]
(1624 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83716024 kinesin family member 21B [Homo sapiens] 3185 0.0
gi|38569484 kinesin family member 21A [Homo sapiens] 1893 0.0
gi|116686122 kinesin family member 4 [Homo sapiens] 396 e-109
gi|150010604 kinesin family member 4B [Homo sapiens] 374 e-103
gi|203096856 kinesin family member 7 [Homo sapiens] 370 e-102
gi|30794488 kinesin family member 27 [Homo sapiens] 357 5e-98
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 283 1e-75
gi|9910266 kinesin family member 15 [Homo sapiens] 271 3e-72
gi|45446749 kinesin family member 5A [Homo sapiens] 270 8e-72
gi|4758650 kinesin family member 5C [Homo sapiens] 267 5e-71
gi|4758648 kinesin family member 5B [Homo sapiens] 266 1e-70
gi|46852174 kinesin family member 3A [Homo sapiens] 263 8e-70
gi|4758646 kinesin family member 3B [Homo sapiens] 262 2e-69
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 260 7e-69
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 260 7e-69
gi|46852172 kinesin family member 13B [Homo sapiens] 253 1e-66
gi|41352705 kinesin family member 3C [Homo sapiens] 238 3e-62
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 238 5e-62
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 238 5e-62
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 238 5e-62
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 238 5e-62
gi|13699824 kinesin family member 11 [Homo sapiens] 235 2e-61
gi|7661878 kinesin family member 14 [Homo sapiens] 234 4e-61
gi|148612831 kinesin family member 18A [Homo sapiens] 233 9e-61
gi|71061468 centromere protein E [Homo sapiens] 225 3e-58
gi|156616271 kinesin family member 19 [Homo sapiens] 221 4e-57
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 220 8e-57
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 220 1e-56
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 219 1e-56
gi|40254834 kinesin family member 1C [Homo sapiens] 218 3e-56
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 3185 bits (8257), Expect = 0.0
Identities = 1624/1624 (100%), Positives = 1624/1624 (100%)
Query: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ
Sbjct: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
Query: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL
Sbjct: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
Query: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA
Sbjct: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
Query: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT
Sbjct: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
Query: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL
Sbjct: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
Query: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT
Sbjct: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
Query: 361 LKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDL 420
LKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDL
Sbjct: 361 LKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDL 420
Query: 421 FRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQN 480
FRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQN
Sbjct: 421 FRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQN 480
Query: 481 YIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV 540
YIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV
Sbjct: 481 YIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV 540
Query: 541 IRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCE 600
IRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCE
Sbjct: 541 IRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCE 600
Query: 601 EEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRL 660
EEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRL
Sbjct: 601 EEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRL 660
Query: 661 QTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRD 720
QTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRD
Sbjct: 661 QTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRD 720
Query: 721 LQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKR 780
LQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKR
Sbjct: 721 LQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKR 780
Query: 781 NREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLK 840
NREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLK
Sbjct: 781 NREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLK 840
Query: 841 PPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQ 900
PPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQ
Sbjct: 841 PPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQ 900
Query: 901 KKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRK 960
KKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRK
Sbjct: 901 KKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRK 960
Query: 961 RERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSV 1020
RERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSV
Sbjct: 961 RERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSV 1020
Query: 1021 VISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDAL 1080
VISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDAL
Sbjct: 1021 VISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDAL 1080
Query: 1081 REKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMKGSTSHDDFKFKSEPK 1140
REKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMKGSTSHDDFKFKSEPK
Sbjct: 1081 REKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMKGSTSHDDFKFKSEPK 1140
Query: 1141 LSAQMKAVSAECLGPPLDISTKNITKSLASLVEIKEDGVGFSVRDPYYRDRVSRTVSLPT 1200
LSAQMKAVSAECLGPPLDISTKNITKSLASLVEIKEDGVGFSVRDPYYRDRVSRTVSLPT
Sbjct: 1141 LSAQMKAVSAECLGPPLDISTKNITKSLASLVEIKEDGVGFSVRDPYYRDRVSRTVSLPT 1200
Query: 1201 RGSTFPRQSRATETSPLTRRKSYDRGQPIRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQ 1260
RGSTFPRQSRATETSPLTRRKSYDRGQPIRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQ
Sbjct: 1201 RGSTFPRQSRATETSPLTRRKSYDRGQPIRSTDVGFTPPSSPPTRPRNDRNVFSRLTSNQ 1260
Query: 1261 SQGSALDKGIISPVGGAKGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMW 1320
SQGSALDKGIISPVGGAKGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMW
Sbjct: 1261 SQGSALDKGIISPVGGAKGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMW 1320
Query: 1321 NLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVI 1380
NLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVI
Sbjct: 1321 NLVTGQEIAALKGHPNNVVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVI 1380
Query: 1381 SGDACAATSTRAITSAQGEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHI 1440
SGDACAATSTRAITSAQGEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHI
Sbjct: 1381 SGDACAATSTRAITSAQGEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHI 1440
Query: 1441 GPVMCLTVTQTASQHDLVVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQ 1500
GPVMCLTVTQTASQHDLVVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQ
Sbjct: 1441 GPVMCLTVTQTASQHDLVVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQ 1500
Query: 1501 GDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWN 1560
GDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWN
Sbjct: 1501 GDILFSGSRDNGIKKWDLDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWN 1560
Query: 1561 VDNFTPIGEIKGHDSPINAICTNAKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRA 1620
VDNFTPIGEIKGHDSPINAICTNAKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRA
Sbjct: 1561 VDNFTPIGEIKGHDSPINAICTNAKHIFTASSDCRVKLWNYVPGLTPCLPRRVLAIKGRA 1620
Query: 1621 TTLP 1624
TTLP
Sbjct: 1621 TTLP 1624
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 1893 bits (4904), Expect = 0.0
Identities = 977/1642 (59%), Positives = 1245/1642 (75%), Gaps = 64/1642 (3%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
V+VAVRIRPQL+KEKIEGCHICTSVTPGEPQV LGKDKAFT+D+VFD+D+ QEQIY C+
Sbjct: 10 VRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCI 69
Query: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIAERK 128
KLIEGCFEGYNATV AYGQTGAGKTYTMGTGFD+ EEE GII RA+ HLF I E+K
Sbjct: 70 EKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSIEEKK 129
Query: 129 RRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIYTTG 188
A + G+ P+FKV+AQFLELYNEE+LDLFD+TRD D + ++SNI+IHED+ GGIYT G
Sbjct: 130 HIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTVG 189
Query: 189 VTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLVNEA 248
VT+R ++++ E++QCLK GALSRTTASTQMNVQSSRSHAIFTIH+CQ R+C Q D N
Sbjct: 190 VTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDADNAT 249
Query: 249 VTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS 308
+ + +E+ETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS
Sbjct: 250 DNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS 309
Query: 309 ALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR 368
ALGD+SK+ HVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR
Sbjct: 310 ALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR 369
Query: 369 NIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQ 428
NIKNKV+VNQD+ SQQI+ALR+EI RLQMELMEYK GKR+I E+G E +D+F ENAMLQ
Sbjct: 370 NIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQ 429
Query: 429 KENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEEL 488
EN LR+R+KAMQE +DA+ +R+TQL+S +AN +LA+AG+GNE I +I +YI+EIE+L
Sbjct: 430 TENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDL 489
Query: 489 RTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDL 548
R KLLESEA+NE+LR++L+RA+AR+PY G+S +P SS ++ E+I AK+DL
Sbjct: 490 RAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTI----LSSDKETIEIIDLAKKDL 545
Query: 549 ERLKKKEVRQRRKSPEKE--AFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGRE 606
E+LK+KE R+++ KE + K +++ E + NE E EE + +EEE E
Sbjct: 546 EKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEE 605
Query: 607 DEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQ 666
+E++D ES +SDS+ +EK N+QADLA++TCEI IKQKLIDELENSQ+RLQTLK Q
Sbjct: 606 EEEDDIDGGESSDESDSESDEK-ANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQ 664
Query: 667 YEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQA 726
YEEKL++LQ+KIRDTQLERD+VLQNL ++E Y+EEKA K++++YEK+L+ MN++LQ+LQA
Sbjct: 665 YEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQA 724
Query: 727 AQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQ 786
AQKEHARLLKNQS+YE++LKKLQ +V EMKK KV LMKQM+EEQ++ RL E++RNREIAQ
Sbjct: 725 AQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQ 784
Query: 787 LKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDS 846
LKK+QR+++ Q+R LE+QKR QE+VLRRKT+EV+ALRR +PMS++VAG+ K D+
Sbjct: 785 LKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDA 844
Query: 847 GAEVSASTTSS-EAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGAS 905
A+ + S+ ++ E ++ +R ++ P P NG RKK+Q+KG +
Sbjct: 845 PAQDTGSSAAAVETDASRTGAQQKMRIPVARVQAL----PTPATNGN---RKKYQRKGLT 897
Query: 906 QS--FSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRER 963
SK AR+KWQ LERR+ DI+MQ+MTI N+EADM RL+K+REEL +E L ++RE+
Sbjct: 898 GRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREK 957
Query: 964 LQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVIS 1023
+ E+ E +K + + EE+E L ANIDYIND I+DCQA I+Q+EE KEE ++ D + VI+
Sbjct: 958 IVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVIN 1017
Query: 1024 SCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREK 1083
+C+L EAR LLD+FL I+KGLQ AQKEAQI++LEGRL+QT++ ++QN LL L+EK
Sbjct: 1018 ACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEK 1077
Query: 1084 AEAHPELQALIYNVQQ-------ENGYASTDEEI---SEFSEGSFSQSFTMKGSTSHDDF 1133
AE +PEL AL+ + Q EN STDE+ S SEGS S MK
Sbjct: 1078 AELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMK-LCGEVKP 1136
Query: 1134 KFKSEPKLSAQMKAVSAECLGPPLDIST--KNITKSLASLVEIKEDGVGFSVRDPYYRDR 1191
K K+ + + QM+ + A+ D ST ++ L + E +E G+ R++
Sbjct: 1137 KNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREK 1196
Query: 1192 -VSRTVSLPTRGSTFPRQS-----RATETSPLTRRKSYDRGQPIR----------STDVG 1235
+S LP++ + RQS + E SP+TRRK+Y++ + + +++
Sbjct: 1197 ELSPPPGLPSKIGSISRQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEAS 1256
Query: 1236 FTPPSSPPTRPRNDRNVFSRLTSNQSQGSALD------------------KGIISPVGGA 1277
+PPSSPP+RPRN+ NVF+RLT +Q S +GII+P +
Sbjct: 1257 LSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPAS 1316
Query: 1278 KGARTAPLQCVSMAEGHTKPILCLDATDELLFTGSKDRSCKMWNLVTGQEIAALKGHPNN 1337
KG R PLQC+ +AEGHTK +LC+D+TD+LLFTGSKDR+CK+WNLVTGQEI +L GHPNN
Sbjct: 1317 KGIRAFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNN 1376
Query: 1338 VVSIKYCSHSGLVFSVSTSYIKVWDIRDSAKCIRTLTSSGQVISGDACAATSTRAITSAQ 1397
VVS+KYC+++ LVF+VSTSYIKVWDIRDSAKCIRTLTSSGQV GDAC+A+++R +
Sbjct: 1377 VVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPS 1436
Query: 1398 GEHQINQIALSPSGTMLYAASGNAVRIWELSRFQPVGKLTGHIGPVMCLTVTQTASQHDL 1457
GE+QINQIAL+P+GT LYAASGNAVR+W+L RFQ GKLTGH+GPVMCLTV Q +S DL
Sbjct: 1437 GENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDL 1496
Query: 1458 VVTGSKDHYVKMFELGECVTGTIGPTHNFEPPHYDGIECLAIQGDILFSGSRDNGIKKWD 1517
++TGSKDHY+KMF++ E GT+ PTHNFEPPHYDGIE L IQGD LFSGSRDNGIKKWD
Sbjct: 1497 IITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWD 1556
Query: 1518 LDQQELIQQIPNAHKDWVCALAFIPGRPMLLSACRAGVIKVWNVDNFTPIGEIKGHDSPI 1577
L Q++L+QQ+PNAHKDWVCAL +P P+LLS CR G++KVWN+D F P+GE+KGHDSPI
Sbjct: 1557 LTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPI 1616
Query: 1578 NAICTNAKHIFTASSDCRVKLW 1599
NAIC N+ HIFTA+ D V++W
Sbjct: 1617 NAICVNSTHIFTAADDRTVRIW 1638
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 396 bits (1017), Expect = e-109
Identities = 325/1108 (29%), Positives = 549/1108 (49%), Gaps = 150/1108 (13%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
V+VA+R RP + KE EGC +C S PGEPQV++G DK+FTYDFVFD T QE++++T V
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
Query: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQ----GIIPRAIAHLFGGI 124
+ LI+G F+GYNATVLAYGQTG+GKTY+MG + T+E+E G+IPR I LF I
Sbjct: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAY---TAEQENEPTVGVIPRVIQLLFKEI 126
Query: 125 AERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGI 184
++ + EF + +LE+YNEEILDL +R+ ++ I I ED GI
Sbjct: 127 DKK---------SDFEFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGI 171
Query: 185 YTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDL 244
G+T + + + + CL+QG SRT AST MN QSSRSHAIFTI L Q +
Sbjct: 172 KIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRK------- 224
Query: 245 VNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 304
S + + +K H VDLAGSER K+T A G+R KEGI+IN GLL LG
Sbjct: 225 -------------KSDKNSSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLG 271
Query: 305 NVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 364
NVISALGD KK VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETLNTL+YA
Sbjct: 272 NVISALGD-DKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYA 330
Query: 365 NRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAG--KRVIGEDGAEGYSDLFR 422
+RAR IKNK +VN D + +++ L+ ++ +LQ+ L++ G I + +E L
Sbjct: 331 DRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLME 390
Query: 423 ENAMLQKENGALRL--------------RVKAMQEAIDAINNRVTQLMSQEANLLLAKAG 468
+N L +EN L R+ ++A + +N ++ +L A L
Sbjct: 391 KNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKL----- 445
Query: 469 DGNEAIGALIQNYIREIEELRTKL--LESEAMNESLRRSLSRASARSPYSLGASPAAPAF 526
D + + L ++E E+ L L ++ +E++ + +
Sbjct: 446 DLQKLVETLEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETS 505
Query: 527 GGSPASSMEDASEVIRRAKQDLERLKKKEVRQ--RRKSPEKEAFKKRAKLQQENSEETDE 584
S A + + A + +K+ +E K +++ RK + ++ + + Q +++ + E
Sbjct: 506 RSSDAFTTQHALRQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELE 565
Query: 585 NEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIE 644
E ++E++E E + ++D ++ SE ++ + +ADL ++
Sbjct: 566 LEVINLQKEKEELVLELQTAKKDANQAKLSERR--------RKRLQELEGQIADLKKKLN 617
Query: 645 IKQKLIDELENSQRRL----QTLKHQYEEKLILLQ------NKIRDTQLERDRVLQNLST 694
+ KL+ E+++R + Q ++ +++ L++ K R + ++D+ + L
Sbjct: 618 EQSKLLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKE 677
Query: 695 MECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAE 754
+ + + K++ +++K+ + R ++ AA K L+ Q + K+ Q+ E
Sbjct: 678 RDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGME 737
Query: 755 MKKAKV------ALMKQMREEQQRRRLVETKRNR-----EIAQLKKEQ----------RR 793
A+V + + E+ +R L + +R ++AQLK+++ RR
Sbjct: 738 GTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRR 797
Query: 794 QEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSAS 853
+ F + + Q + E + ++ + L M R A A L+ +LD+ +E
Sbjct: 798 RTFSLTEVRGQVSESEDSITKQ------IESLETEMEFRSAQIADLQQKLLDAESE---- 847
Query: 854 TTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAAR 913
+ ++++I+ + + + +G+ + + ++ + QS + A
Sbjct: 848 ---DRPKQRWENIATIL-EAKCALKYLIGELVSSKIQVSK------LESSLKQSKTSCAD 897
Query: 914 LKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFL---------------LQEALR 958
++ E R ++ L+A++ R+ ++ +E L L+E++
Sbjct: 898 MQKMLFEERNHFAEIE----TELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVS 953
Query: 959 RKRERLQAE---SPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDS 1015
K ++L + EE + ++E+ E+ + L + I +T Q Q K+ L S
Sbjct: 954 EKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLTLLQVASRQKHLPKDTLLS 1013
Query: 1016 TDTSVVISSCSLAEARLLLDNFLKASID 1043
D+S +R + + FL+ S+D
Sbjct: 1014 PDSSFEYVPPKPKPSR-VKEKFLEQSMD 1040
Score = 128 bits (321), Expect = 5e-29
Identities = 141/682 (20%), Positives = 288/682 (42%), Gaps = 81/682 (11%)
Query: 448 INNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLS 507
+N+ Q+ + LL A G +I ++ + E L+E NE L R LS
Sbjct: 351 LNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQSLVEE---NEKLSRGLS 407
Query: 508 RASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEA 567
A+ ++ L + +E+ + K DL++L V KE
Sbjct: 408 EAAGQTAQMLERIILTEQANEKMNAKLEELRQHAA-CKLDLQKL----VETLEDQELKEN 462
Query: 568 FKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEE 627
+ LQQ ++ +DE A ++ E+E E E S S ++ +
Sbjct: 463 VEIICNLQQLITQLSDETVACMAAAI--DTAVEQEAQVETSPETSRSSDAFTTQHA---L 517
Query: 628 KEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDR 687
++ +L +L + +K+ L ++ + +LQ +++QY++ + L+ ++ + Q E++
Sbjct: 518 RQAQMSKELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEE 577
Query: 688 VLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKK 747
++ L T + + K+ KRL+E+ + L+ E ++LLK + ER + K
Sbjct: 578 LVLELQTAK--KDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKLKESTERTVSK 635
Query: 748 LQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQ 807
L E+ MK +V LM+QM+E+ ++ R + K+++E+ QLK+ R++++++ LE ++
Sbjct: 636 LNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQK 695
Query: 808 QEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVS 867
Q VLRRKT+E +A + K ++ A + G E +A+
Sbjct: 696 QSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAA-------------- 741
Query: 868 SIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIV 927
++ ++LG+ V+ + +R + D++
Sbjct: 742 --------RVKNWLGNEIEVMVS-------------------------TEEAKRHLNDLL 768
Query: 928 MQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAA 987
R L D+ +L +K+E LRR+ L + + + ++IE L
Sbjct: 769 EDRKI---LAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQIESLET 825
Query: 988 NIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQ 1047
+++ + I D Q ++ E + + ++ EA+ L + + +Q
Sbjct: 826 EMEFRSAQIADLQQKLLDAESEDRPKQRWE-----NIATILEAKCALKYLIGELVSSKIQ 880
Query: 1048 VAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENG----Y 1103
V++ LE L+Q+ + + +L + AE ELQA + ++Q++ Y
Sbjct: 881 VSK-------LESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLY 933
Query: 1104 ASTDEEISEFSEGSFSQSFTMK 1125
+ + S+ +E +S + K
Sbjct: 934 LLSQLQQSQMAEKQLEESVSEK 955
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 374 bits (959), Expect = e-103
Identities = 284/885 (32%), Positives = 455/885 (51%), Gaps = 91/885 (10%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
V+VA+R RP + KE EGC +C S PGE QV++G DK+FTYDFVFD T QE++++ V
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
Query: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQ----GIIPRAIAHLFGGI 124
+ LI+G F+GYNATVLAYGQTG+GKTY+MG + T+E+E GIIPR I LF I
Sbjct: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAY---TAEQENEPTVGIIPRVIQLLFKEI 126
Query: 125 AERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGI 184
++ + EF + +LE+YNEEILDL +R+ ++ I I ED GI
Sbjct: 127 DKK---------SDFEFTLKVSYLEIYNEEILDLLCPSRE------KAQINIREDPKEGI 171
Query: 185 YTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDL 244
G+T + + + + CL+QG SRT AST MN QSSRSHAIFTI + Q +
Sbjct: 172 KIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRK------- 224
Query: 245 VNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 304
S + + +K H VDLAGSER K+T A G+R KEGI+IN GLL LG
Sbjct: 225 -------------KSDKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLG 271
Query: 305 NVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 364
NVISALGD KK VPYRDSKLTRLLQDSLGGNS T+MIACVSP+D + ETL+TL+YA
Sbjct: 272 NVISALGD-DKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYA 330
Query: 365 NRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAG--KRVIGEDGAEGYSDLFR 422
+RAR IKNK +VN D + +++ L+ ++ +LQ+ L++ G I + +E L
Sbjct: 331 DRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLME 390
Query: 423 ENAMLQKENGAL-RLRVKAMQEAIDAINNRV-TQLMSQEANLLLAKAG-------DGNEA 473
+N L +EN L R KA + + + T+ ++++ N L + D +
Sbjct: 391 KNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKL 450
Query: 474 IGALIQNYIREIEELRTKL--LESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPA 531
+ L ++E E+ L L ++ +E++ + + + S A
Sbjct: 451 VETLEDQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDA 510
Query: 532 SSMEDASEVIRRAKQDLERLKKKEVRQR--RKSPEKEAFKKRAKLQQENSEETDENEAEE 589
+ + A + +K+ +E +++ RK + + + + Q +++ + E E
Sbjct: 511 FTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVIN 570
Query: 590 EEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKL 649
++E++E E + +++ ++ SE + + +ADL ++ + KL
Sbjct: 571 LQKEKEELVRELQTAKKNVNQAKLSEHR--------HKLLQELEGQIADLKKKLNEQSKL 622
Query: 650 IDELENSQRRLQTLKHQY----EEKLILLQ------NKIRDTQLERDRVLQNLSTMECYT 699
+ E+++R + L + +++ L++ K R + ++D+ + L +
Sbjct: 623 LKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKR 682
Query: 700 EEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAK 759
+ + K++ +++K+ + R ++ AA K L+ Q + K+ Q+ E A+
Sbjct: 683 QYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAAR 742
Query: 760 V------ALMKQMREEQQRRRLVETKRNR-----EIAQLKKEQRRQEFQIRALE----SQ 804
V + + E+ +R L + +R ++ QLK+++ +E L S
Sbjct: 743 VRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKESRENPPPKLRKCTFSL 802
Query: 805 KRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAE 849
VL + + L M R A A L+ +LD+ +E
Sbjct: 803 SEVHGQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESE 847
Score = 122 bits (307), Expect = 2e-27
Identities = 142/682 (20%), Positives = 285/682 (41%), Gaps = 81/682 (11%)
Query: 448 INNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLS 507
+N+ Q+ + LL A G +I A ++ + E L+E NE L R LS
Sbjct: 351 LNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEE---NEKLSRCLS 407
Query: 508 RASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEA 567
+A+ ++ L + +E+ + + K DL++L V KE
Sbjct: 408 KAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVA-CKLDLQKL----VETLEDQELKEN 462
Query: 568 FKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEE 627
+ LQQ ++ +DE A ++ EEE E E S S ++ +
Sbjct: 463 VEIICNLQQLITQLSDETVACTAAAI--DTAVEEEAQVETSPETSRSSDAFTTQHA---L 517
Query: 628 KEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDR 687
+ ++ +L + +K+ L+ ++ + +LQ ++ QY++ + L+ ++ + Q E++
Sbjct: 518 HQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKEKEE 577
Query: 688 VLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKK 747
+++ L T + + K+ K L+E+ + L+ E ++LLK + ER + K
Sbjct: 578 LVRELQTAKKNVNQA--KLSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSK 635
Query: 748 LQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQ 807
L E+ MK +V LM+QM+E+ ++ R + K+++E+ QLK+ R++++++ LE ++
Sbjct: 636 LNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQK 695
Query: 808 QEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVS 867
Q VLRRKT+E +A + K L EV+ +++ G ++
Sbjct: 696 QSSVLRRKTEEAAAANKRLKDA--------------LQKQREVTDKRKETQSH-GKEGIA 740
Query: 868 SIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIV 927
+ VR W LG+ V+ + +R + D++
Sbjct: 741 ARVRNW-------LGNEIEVMVST-------------------------EEAKRHLNDLL 768
Query: 928 MQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAA 987
R + D+ +L +K+E LR+ L + + + ++IE L
Sbjct: 769 EDRKILAQ---DVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLESEDCITKQIESLET 825
Query: 988 NIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQ 1047
++ + I D Q ++ E + I EA+ L + + +
Sbjct: 826 EMELRSAQIADLQQKLLDAESEDRPKQCWENIATI-----LEAKCALKYLIGELVSSKIH 880
Query: 1048 VAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENG----Y 1103
V + LE LRQ+ + + +L + +E ELQA + ++Q++ Y
Sbjct: 881 VTK-------LENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLY 933
Query: 1104 ASTDEEISEFSEGSFSQSFTMK 1125
+ + S+ +E +S + K
Sbjct: 934 LVSQLQESQMAEKQLEKSASEK 955
Score = 35.0 bits (79), Expect = 0.59
Identities = 36/167 (21%), Positives = 78/167 (46%), Gaps = 11/167 (6%)
Query: 560 RKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLV 619
R+S A ++ +++N E E + E ++ E+ + ++S E +
Sbjct: 889 RQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQLQESQMAEKQL 948
Query: 620 DSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIR 679
+ + +E+++ ++ L C+ E +K+ + E +Q+ LQ ++KLILLQ R
Sbjct: 949 EKSASEKEQQL-----VSTLQCQDEELEKMREVCEQNQQLLQE-NEIIKQKLILLQVASR 1002
Query: 680 DTQLERDRVLQNLSTMECY-TEEKANKIKADYEKRLREMNRDLQKLQ 725
L D +L S+ E + K +++K ++ E + D++ L+
Sbjct: 1003 QKHLPNDTLLSPDSSFEYIPPKPKPSRVK----EKFLEQSMDIEDLK 1045
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 370 bits (951), Expect = e-102
Identities = 327/1173 (27%), Positives = 530/1173 (45%), Gaps = 159/1173 (13%)
Query: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
+ G + V+VA+R+RP L KE + G C V PG +V LG+D+ F + V D Q
Sbjct: 8 LPGAEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQ 67
Query: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
E +Y CV L+E FEG+NATV AYGQTG+GKTYTMG + E+EQGI+PRA+A
Sbjct: 68 EAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPRAMAEA 127
Query: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFD---STRDPDTRHRRSNIKIH 177
F I E + V +LE+Y EE DL + ++RD I++
Sbjct: 128 FKLIDENDLL---------DCLVHVSYLEVYKEEFRDLLEVGTASRD---------IQLR 169
Query: 178 EDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMR 237
ED G + GV + +E++ L+ G +R T +T +N SSRSH +FT+ L Q
Sbjct: 170 EDERGNVVLCGVKEVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRG 229
Query: 238 MCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISIN 297
P P + + L +KFHFVDLAGSER+ +TG+TGER KE I IN
Sbjct: 230 RA-------------PSRLPRPAPGQLLVSKFHFVDLAGSERVLKTGSTGERLKESIQIN 276
Query: 298 CGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMET 357
LLALGNVISALGD ++ H+PYRDSK+TR+L+DSLGGN++T+MIACVSPS DF ET
Sbjct: 277 SSLLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDET 336
Query: 358 LNTLKYANRARNIKNKVVVN----QDKTSQQISALRAEIARLQMELMEYKAGKRVIGED- 412
LNTL YA+RA+NI+N+ VN ++ ++ ++ R + E G+R G
Sbjct: 337 LNTLNYASRAQNIRNRATVNWRPEAERPPEETASGARGPPRHRSETRIIHRGRRAPGPAT 396
Query: 413 ---------GAE----------GYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVT 453
GAE YS L RE GA +V+ A++ + ++
Sbjct: 397 ASAAAAMRLGAECARYRACTDAAYS-LLRELQAEPGLPGAAARKVRDWLCAVEGERSALS 455
Query: 454 QLMSQEANLLLAK--------AGDGNEAIGA----LIQNYIREIEE------------LR 489
++ + A AG E GA +QN + +EE +
Sbjct: 456 SASGPDSGIESASVEDQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAME 515
Query: 490 TKLLESEAMNES--------LRRSLSRASARSPYSLGASP---------AAPAFGGSPAS 532
L+S+ + E LR L R P L P AP GG+ A
Sbjct: 516 QYKLQSDRLREQQEEMVELRLRLELVRPGWGGPRLLNGLPPGSFVPRPHTAP-LGGAHAH 574
Query: 533 SMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEE 592
+ + + ++V R++ E + +L +S ++E E EEE
Sbjct: 575 VLGMVPPACLPGDEVGSEQRGEQVTNGREA-GAELLTEVNRLGSGSSAASEEEEEEEEPP 633
Query: 593 ERD-------ESGCEEEEGREDED--EDSGSEESLVDSD--------------------- 622
R S C + G E G E L + D
Sbjct: 634 RRTLHLRRNRISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKARVQARQV 693
Query: 623 ---SDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQ---N 676
+ E + Q + +L I +K++LI EL + + Q L Q+ +++ L+
Sbjct: 694 PPATASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAE 753
Query: 677 KIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLK 736
++R E R L+ L E + ++++ ++ +R+ +Q L+ ++ RL+
Sbjct: 754 QVRAELSEGQRQLRELEGKELQDAGERSRLQ-EFRRRVAAAQSQVQVLKEKKQATERLVS 812
Query: 737 NQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEF 796
++ E+ L++L+ V M++ + L +++REE +++R +E A++ K Q R
Sbjct: 813 LSAQSEKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLE-------AEMSKRQHR--- 862
Query: 797 QIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTS 856
++ LE + QQ+ +L+ KT+E++A +R K S L+ +
Sbjct: 863 -VKELELKHEQQQKILKIKTEEIAAFQR--KRRSGSNGSVVSLEQQQKIEEQKKWLDQEM 919
Query: 857 SEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKW 916
+ R++ + + +++ L A T K+ + A +
Sbjct: 920 EKVLQQRRALEELGEELHKR-EAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRL 978
Query: 917 QSLERRIIDIVMQ-----RMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEE 971
+ LE+ + + Q + + +++ L ++++ L + + K + SPEE
Sbjct: 979 EHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEE 1038
Query: 972 EKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEAR 1031
E+ L +L E IE L A I+Y N+ IT C+ +++ + + +S S +E R
Sbjct: 1039 ERTLFQLDEAIEALDAAIEYKNEAIT-CRQRVLRASASLLSQCEMNLMAKLSYLSSSETR 1097
Query: 1032 LLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQ 1064
LL + + + Q++ LE +L +
Sbjct: 1098 ALLCKYFDKVVTLREEQHQQQIAFSELEMQLEE 1130
Score = 50.8 bits (120), Expect = 1e-05
Identities = 157/739 (21%), Positives = 293/739 (39%), Gaps = 157/739 (21%)
Query: 378 QDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGY---SDLFRENAMLQKENGAL 434
+D+ +QQ+ L+ ++ARL+ E ++ A ED E Y SD RE Q+E L
Sbjct: 482 EDEGAQQLLTLQNQVARLEEENRDFLAAL----EDAMEQYKLQSDRLREQ---QEEMVEL 534
Query: 435 RLRVKAMQEAIDA---INN----------RVTQLMSQEANLL-----LAKAGD--GNEAI 474
RLR++ ++ +N L A++L GD G+E
Sbjct: 535 RLRLELVRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVGSEQR 594
Query: 475 GALIQNYIREIEELRTKLL-----------ESEAMNESLRRSL-----------SRASAR 512
G + N EL T++ E E E RR+L RA AR
Sbjct: 595 GEQVTNGREAGAELLTEVNRLGSGSSAASEEEEEEEEPPRRTLHLRRNRISNCSQRAGAR 654
Query: 513 SPYSL--------------GASPAAPAFGGS----------PASSME----DASEVIR-- 542
P SL A P + A GGS PA++ E A + IR
Sbjct: 655 -PGSLPERKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRLAQAQQKIREL 713
Query: 543 ----RAKQDL----------ERLKKKEVRQRRKSPEKEAFKKRAKLQQ--------ENSE 580
R K++L + ++ QR + E+EA + RA+L + E E
Sbjct: 714 AINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKE 773
Query: 581 ETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESL---VDSDSDPEEKEVNFQADLA 637
D E +E R + + + +++ +E + S+ +E E N Q
Sbjct: 774 LQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQ 833
Query: 638 D-------LTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRD-TQLERDRVL 689
L E E K++L E+ Q R++ L+ ++E++ +L+ K + +R R
Sbjct: 834 QQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKR-- 891
Query: 690 QNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQ 749
++ S + E+ KI+ + +EM + LQ+ +A ++ L K ++ ++ +Q
Sbjct: 892 RSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQ 951
Query: 750 AEV---AEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKR 806
+ ++ ++ AL + + R +E + + + QL++ + + QIR R
Sbjct: 952 EKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLR 1011
Query: 807 QQEMVLRRKTQEVSALRR---LAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGA 863
Q++ L ++ E+ R L P ER + LD+ E + +
Sbjct: 1012 QEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCR-QRVL 1070
Query: 864 RSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRI 923
R+ +S++ Q + + + + TR K+ F K L+ + +
Sbjct: 1071 RASASLLSQCEMNL---MAKLSYLSSSETRALLCKY--------FDKVVTLREEQHQ--- 1116
Query: 924 IDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKR----ERLQAESPEEEKGLQELA 979
Q++ LE +E +++ ++ L+ AL R+R +L + E E+ +Q L
Sbjct: 1117 -----QQIAFSELEMQLE---EQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLL 1168
Query: 980 EEIEVLAANIDYINDGITD 998
++ + D++ +G+ D
Sbjct: 1169 QQ------SRDHLGEGLAD 1181
Score = 40.4 bits (93), Expect = 0.014
Identities = 99/497 (19%), Positives = 186/497 (37%), Gaps = 84/497 (16%)
Query: 383 QQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQ 442
Q+ +RAE++ Q +L E + GK + + R A Q + L+ + +A +
Sbjct: 750 QEAEQVRAELSEGQRQLRELE-GKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATE 808
Query: 443 EAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESL 502
+ +L E N+ L + G +Q +RE E + +L + +
Sbjct: 809 RLVSLSAQSEKRLQELERNVQLMRQQQGQ------LQRRLREETEQKRRLEAEMSKRQHR 862
Query: 503 RRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKK-------KE 555
+ L + L A S + S V +Q +E KK K
Sbjct: 863 VKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKV 922
Query: 556 VRQRRKSPE-------KEAF--KKRAKLQQENSEETDENEAEE----------------E 590
++QRR E +EA KK A +Q++ E+ + + E
Sbjct: 923 LQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLE 982
Query: 591 EEERDESGCEEEEGREDEDEDSGSEESL-VDSDS------------------DPEEKEVN 631
+E ++SG + + + + G +SL + DS PEE+
Sbjct: 983 KELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTL 1042
Query: 632 FQADLA--DLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQ------- 682
FQ D A L IE K + I + R +L Q E L+ + + ++
Sbjct: 1043 FQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCK 1102
Query: 683 -------LERDRVLQNL--STMECYTEEKANKI---KADYEKRLREMNRDLQKLQAAQKE 730
L ++ Q + S +E EE+ + + E++ EM+R L Q ++
Sbjct: 1103 YFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQ 1162
Query: 731 HARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKE 790
+ +LL QSR L +A+ ++ A ++ + +E R + + +++ +
Sbjct: 1163 NMQLLLQQSR-----DHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAV 1217
Query: 791 QRRQEFQIRALESQKRQ 807
+ + R+L S+ RQ
Sbjct: 1218 GHSRGGEKRSLCSEGRQ 1234
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 357 bits (916), Expect = 5e-98
Identities = 319/1162 (27%), Positives = 520/1162 (44%), Gaps = 177/1162 (15%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYSTCV 68
VKVAVRIRP L KE + +C V P QV++G+D+ FT+DFVF ++ Q+++Y+TC+
Sbjct: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYNTCI 65
Query: 69 SKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIAERK 128
L+ EGYNATV AYGQTG+GKTYT+G G + E ++GIIPRAI +F I+E
Sbjct: 66 KPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQSISEHP 125
Query: 129 RRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIYTTG 188
+F V ++E+Y E++ DL + H I ED G G
Sbjct: 126 ---------SIDFNVKVSYIEVYKEDLRDLLELETSMKDLH------IREDEKGNTVIVG 170
Query: 189 VTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLVNEA 248
+ S E++ L+ G +R T +TQMN SSRSHAIFTI +CQ V++
Sbjct: 171 AKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQ---------VHKN 221
Query: 249 VTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVIS 308
+ DG+ S + + +KFHFVDLAGSER+ +TG TGER KE I IN GLLALGNVIS
Sbjct: 222 MEAAEDGSWYSPRH--IVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVIS 279
Query: 309 ALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRAR 368
ALGD +K H+PYRD+K+TRLL+DSLGG+++T+MI CVSPS +F E+LN+LKYANRAR
Sbjct: 280 ALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRAR 339
Query: 369 NIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQ 428
NI+NK VN S +I + EI L+ L +AG + +
Sbjct: 340 NIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQQAG---------------VSQTTQIN 384
Query: 429 KENGALRLRVKAMQEAIDAINNRVT--QLMSQEANLLLAKAGDG---NEAIGALIQNYIR 483
+E R+ +++E + + Q +EA L D NE +Q +
Sbjct: 385 REGSPDTNRIHSLEEQVAQLQGECLGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFN 444
Query: 484 EIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRR 543
I+E+R +L S GG+ + + +
Sbjct: 445 MIQEVRKAVLTS---------------------------FRGIGGTASLEEGPQHVTVLQ 477
Query: 544 AKQDLER----LKKKEVRQRRKSPEKEAFKKRAKL--QQENSEETDENEAEEEEEERDES 597
K++L++ L EV +K E + K + ++ Q+ EA++ ++E
Sbjct: 478 LKRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAVSLKEAQKVNRLQNEK 537
Query: 598 GCEEEEGREDEDED---------SGSEESLVDSDSD--PEEKEVNFQADLADLTCEIEIK 646
E++ + E+ S ++E+ D PE + D +
Sbjct: 538 IIEQQLLVDQLSEELTKLNLSVTSSAKENCGDGPDARIPERRPYTVPFD-------THLG 590
Query: 647 QKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQL-----ERDRVL-----QNLSTME 696
+ R++ T Y I + R L E+D+VL N E
Sbjct: 591 HYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIEEQDKVLHCQFSDNSDDEE 650
Query: 697 CYTEEKANK--------IKADYEKRLREMNRDLQKLQAAQKEHARL-------------- 734
+EK+ K D L E++ + Q + E+ L
Sbjct: 651 SEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQ 710
Query: 735 -LKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRR 793
LKN R E K+ E+ K K L+K++ + + V + + ++ +L E
Sbjct: 711 KLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKL--EHDA 768
Query: 794 QEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSAS 853
++ ++ +E+QK+ QE+ + +V+ +L K +++ A L+ +L + S
Sbjct: 769 EQAKVELIETQKQLQELE-NKDLSDVAMKVKLQKEFRKKM-DAAKLRVQVLQKKQQDSKK 826
Query: 854 TTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAAR 913
S ++ R+ + + ++H K+QK +
Sbjct: 827 LASLSIQNEKRA-----NELEQSVDHM-----------------KYQK------IQLQRK 858
Query: 914 LKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEK 973
L+ ++ +R+ +D V++R D ++ IK+ + +E L+ K E L A + + K
Sbjct: 859 LREENEKRKQLDAVIKR--------DQQK-IKEIQLKTGQEEGLKPKAEDLDACNLKRRK 909
Query: 974 GLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLL 1033
G + ++ L ++++ + +LEE + +L + V L E L
Sbjct: 910 GSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHL 969
Query: 1034 LDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMAGSSQNHLLLDALREKAEA----HPE 1089
+ L++S + ++ LLE L + ++ + + E+ E +
Sbjct: 970 ENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQ 1029
Query: 1090 LQALIYNVQQ--ENGYASTDEE 1109
LQ +NV + +NG + EE
Sbjct: 1030 LQKRRHNVDEKLKNGRVLSPEE 1051
Score = 94.0 bits (232), Expect = 1e-18
Identities = 122/574 (21%), Positives = 246/574 (42%), Gaps = 77/574 (13%)
Query: 579 SEETDENEAEEEEE-----------ERDESGCE--EEEGREDEDEDSGSEESLVDSDSDP 625
S+ +D+ E+E +E+ ++ +S C E +DE + S E + D
Sbjct: 643 SDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLENEDLKIDCLQ 702
Query: 626 EEKEVNFQA-------------DLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLI 672
E +E+N Q + +LT I++K+ LI EL + +++ QY K+
Sbjct: 703 ESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVT 762
Query: 673 LLQNKIRDTQ---LERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQK 729
L++ + +E + LQ L + K++ ++ K++ +Q LQ Q+
Sbjct: 763 KLEHDAEQAKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQ 822
Query: 730 EHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKK 789
+ +L + E+ +L+ V MK K+ L +++REE ++R+ ++ R+
Sbjct: 823 DSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRD------ 876
Query: 790 EQRRQEFQIRALESQKRQQEMVLRRKTQEVSAL---RRLAKPMSERVAGRAGLKPPMLDS 846
+Q+ +E Q+ K QE L+ K +++ A RR S + + LD
Sbjct: 877 QQKIKEIQL------KTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDE 930
Query: 847 GAE--VSASTTSSEAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGA 904
E ++ E E+ + +IV + + + KK + A
Sbjct: 931 EVEKVLNQRQELEELEADLKKREAIVSKKEALLQE-----------KSHLENKKLRSSQA 979
Query: 905 SQSFSKAARLKWQSLERRIIDIVMQRMTIV-----NLEADMERLIKKREELFLLQEALRR 959
+ S + LE+ + + +Q T + +E L K++++L + +
Sbjct: 980 LNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDE 1039
Query: 960 KRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDTS 1019
K + + SPEEE L +L E IE L A I+Y N+ I + Q + L + L + +
Sbjct: 1040 KLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKS---LRASFHNLSRGEAN 1096
Query: 1020 VV--ISSCSLAEARLLLDNFLKASI-----DKGLQVAQKEAQIRLLEGRLRQTDMAGSSQ 1072
V+ ++ S E R +L + + ++ Q+ +E ++++LE R S+
Sbjct: 1097 VLEKLACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLE-RDNMVRELESAL 1155
Query: 1073 NHLLLDALR----EKAEAHPELQALIYNVQQENG 1102
+HL L R ++ E ++Q L+++ ++++G
Sbjct: 1156 DHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDG 1189
Score = 33.1 bits (74), Expect = 2.2
Identities = 70/376 (18%), Positives = 142/376 (37%), Gaps = 58/376 (15%)
Query: 478 IQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDA 537
+ N +E+EEL L + EA+ L S L +S A D+
Sbjct: 935 VLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKLRSSQALNT----------DS 984
Query: 538 SEVIRRAKQDLERLKKKEVR-QRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERD- 595
++ R + L +K V+ Q + EK ++ ++ Q+ ++ + +E+ ++
Sbjct: 985 LKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNG 1044
Query: 596 --------------ESGCEEEEGREDEDEDS--GSEESLVDSDSDPEEKEVNFQADLADL 639
E G E E + +S ++SL S + E N LA L
Sbjct: 1045 RVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGEANVLEKLACL 1104
Query: 640 TCEIEIKQKL------IDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRV-LQNL 692
+ +EI+ L + L ++R+ Q + + K++ N +R+ + D + LQ
Sbjct: 1105 S-PVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVRELESALDHLKLQCD 1163
Query: 693 STMECYTEEKANKIKA------------------DYEKRLREMNRDLQKLQAAQKEHARL 734
+ +E K++ YE +++++ +DL + ++H +
Sbjct: 1164 RRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTSRDHKKK 1223
Query: 735 LKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQ 794
LK E + Q +E ++A ++K L R E +L +R
Sbjct: 1224 LK---ELVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEELKWASR-PESMKLSGREREM 1279
Query: 795 EFQIRALESQKRQQEM 810
+ +L +Q Q++
Sbjct: 1280 DSSASSLRTQPNPQKL 1295
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 283 bits (723), Expect = 1e-75
Identities = 261/860 (30%), Positives = 413/860 (48%), Gaps = 141/860 (16%)
Query: 9 VKVAVRIRPQLSKEK-IEGCHIC------TSVTPGE-PQVLLG-----KDKAFTYDFVF- 54
VKVAVR+RP +EK +E I T++T + P+ G + K FTYDF F
Sbjct: 4 VKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSFY 63
Query: 55 DLDTW------QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEE 108
DT QE ++ T + +++ FEGYNA V AYGQTG+GK+YTM +
Sbjct: 64 SADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTM------MGNSG 117
Query: 109 EQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTR 168
+ G+IPR LF I E R + F+ +LE+YNE + DL
Sbjct: 118 DSGLIPRICEGLFSRINETTRWDEAS------FRTEVSYLEIYNERVRDLLRRKSS---- 167
Query: 169 HRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAI 228
+ N+++ E G Y ++ L+ + ++ + + G ++RTTA+T MN SSRSHAI
Sbjct: 168 -KTFNLRVREHPKEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAI 226
Query: 229 FTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGE 288
FTI Q + ++ +P T +K H VDLAGSER TGATG
Sbjct: 227 FTIKFTQAKFDSE----------MPCET---------VSKIHLVDLAGSERADATGATGV 267
Query: 289 RAKEGISINCGLLALGNVISALGDQS---------KKVVHVPYRDSKLTRLLQDSLGGNS 339
R KEG +IN L+ LGNVISAL D S KK V VPYRDS LT LL+DSLGGNS
Sbjct: 268 RLKEGGNINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNS 327
Query: 340 QTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMEL 399
+TIMIA +SP+D ++ ETL+TL+YANRA+NI NK +N+D + I LRAEIARL+ L
Sbjct: 328 KTIMIATISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLL 387
Query: 400 MEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNR--VTQLMS 457
+ G ++ D S E + Q E +QE N+ TQ +
Sbjct: 388 AQ---GNQIALLDSPTALS---MEEKLQQNE--------ARVQELTKEWTNKWNETQNIL 433
Query: 458 QEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRS---LSRASARSP 514
+E L L K E IG ++ + + + + LL + + L+ + R A +
Sbjct: 434 KEQTLALRK-----EGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTE 488
Query: 515 Y-----------------SLGASPAAPAFGGSPAS----SMEDASEVIRRAKQDLERLKK 553
++G + GS S + +A+ + + A L R
Sbjct: 489 QDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNM 548
Query: 554 KEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEE--RDESGCEEEEGREDEDED 611
+++ + +K L + TD +++ E G E E + +E E
Sbjct: 549 FRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQREELEK 608
Query: 612 SGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKL 671
S+ L++ + EEK+ + +A+L + E+E ++K E E Q +++ + + +
Sbjct: 609 LESKRKLIE---EMEEKQKSDKAELERMQQEVETQRK---ETEIVQLQIRKQEESLKRRS 662
Query: 672 ILLQNKIRDTQLERD-------RVLQNLSTMECYTEEKANKIKADYEKRLREMNRD---- 720
++NK++D E++ R Q + + EE+ + +RL+E+N +
Sbjct: 663 FHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAE 722
Query: 721 ----LQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREE-QQRRRL 775
Q+L QKE K++ + EL+K + E E +K +V L+ + E+ ++++ +
Sbjct: 723 KFQIFQELDQLQKE-----KDEQYAKLELEKKRLE--EQEKEQVMLVAHLEEQLREKQEM 775
Query: 776 VETKRNREIAQLKKEQRRQE 795
++ R E+ +++E+R E
Sbjct: 776 IQLLRRGEVQWVEEEKRDLE 795
Score = 58.2 bits (139), Expect = 7e-08
Identities = 156/743 (20%), Positives = 298/743 (40%), Gaps = 90/743 (12%)
Query: 300 LLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLN 359
LLA GN I+ L DS +++ L N + +++ + ET N
Sbjct: 386 LLAQGNQIALL-------------DSPTALSMEEKLQQNEARVQELTKEWTNK-WNETQN 431
Query: 360 TLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSD 419
LK A K + V D + + ++ + L K G+ +G D A D
Sbjct: 432 ILKEQTLALR-KEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQD 490
Query: 420 LFRENAMLQKEN-------GALRL-RVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGN 471
+ L+ E+ G + L + Q +++ + ++Q A +LL +
Sbjct: 491 IVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTN--- 547
Query: 472 EAIGALIQNYIREIEELRTK----LLESEAMNES-LRRSLSRASARSPYSLGASPAAPAF 526
N+ +E +LR K LL S +++ + L +S SA Y+ G
Sbjct: 548 ----MFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFERQQR 603
Query: 527 GG-----SPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSP-------EKEAFKKRAKL 574
S +E+ E + K +LER++++ QR+++ ++E KR
Sbjct: 604 EELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSF 663
Query: 575 QQENSEETDENEAEEEEEE--RDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNF 632
EN + E E+ EEE R++ E ++ R++E+ +E L +E N
Sbjct: 664 HIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEEL----QRLKELNNNE 719
Query: 633 QADLADLTCEIEIKQKLIDE----LENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRV 688
+A+ + E++ QK DE LE ++RL+ + E++ ++L + + E+ +
Sbjct: 720 KAEKFQIFQELDQLQKEKDEQYAKLELEKKRLE----EQEKEQVMLVAHLEEQLREKQEM 775
Query: 689 LQNLSTMEC-YTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRY----ER 743
+Q L E + EE+ K D E + R + ++ L K Q R+ R
Sbjct: 776 IQLLRRGEVQWVEEE----KRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRR 831
Query: 744 ELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKK--EQRRQEFQIRAL 801
+L KL ++ + K L K+++EEQ+ ++ + ++E L+K E ++
Sbjct: 832 QLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQD 891
Query: 802 ESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAES 861
+ + E L+ K +++ L + P RA +LD G +S T + E
Sbjct: 892 FEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAF---EILDRG-PLSLDNTLYQVEK 947
Query: 862 GARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLER 921
+ Q+ N +++ +K + + + ++LER
Sbjct: 948 EMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQREALER 1007
Query: 922 RIIDI-----VMQRMTIVNLEADMERLIKKREELFLLQEALRRK---RERLQAESPEEEK 973
+ + +QR + + +E + ++R++L L R + + L+AE EK
Sbjct: 1008 ALARLERRHSALQRHSTLGMEIE-----EQRQKLASLNSGSREQSGLQASLEAEQEALEK 1062
Query: 974 GLQELAEEIEVLAANIDYINDGI 996
+ L EI+ L I Y DG+
Sbjct: 1063 DQERLEYEIQQLKQKI-YEVDGV 1084
Score = 37.0 bits (84), Expect = 0.16
Identities = 80/442 (18%), Positives = 172/442 (38%), Gaps = 72/442 (16%)
Query: 700 EEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAK 759
E++ + + + + + ++++ + L A + L E ++ Q E E ++K
Sbjct: 562 EKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGL---------EFERQQREELEKLESK 612
Query: 760 VALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEV 819
L+++M E+Q+ + E+ ++++E Q + ++ Q R+QE L+R++ +
Sbjct: 613 RKLIEEMEEKQKSDK-------AELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHI 665
Query: 820 SALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINH 879
+ + +A + + L E+ E E+ R + R +++N+
Sbjct: 666 E------NKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRL--KELNN 717
Query: 880 FLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEAD 939
+KFQ K ++ LE + Q V L A
Sbjct: 718 -------------NEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAH 764
Query: 940 MERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDC 999
+E +++++E+ L LRR + E + +G++E ++ A D + +
Sbjct: 765 LEEQLREKQEMIQL---LRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKA 821
Query: 1000 Q-----------ATIVQLEE--------TKEELDSTDTSVVISSCSLAEARLLLDNFLKA 1040
Q +V LE+ K+E+ + C + LL+
Sbjct: 822 QLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKH-DE 880
Query: 1041 SIDKGLQVAQKEAQIRLLEGRL--RQTDMAGSSQNHLLLDALREKAEAHP-------ELQ 1091
S+ +V Q +I+ +E RL ++ + QNH L L EK A L
Sbjct: 881 SVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNH-LPTLLEEKQRAFEILDRGPLSLD 939
Query: 1092 ALIYNVQQENGYASTDEEISEF 1113
+Y V++E +E+++++
Sbjct: 940 NTLYQVEKE--MEEKEEQLAQY 959
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 271 bits (694), Expect = 3e-72
Identities = 312/1181 (26%), Positives = 507/1181 (42%), Gaps = 183/1181 (15%)
Query: 2 AGQGDCCVKVAVRIRPQLSKE-KIEG-CHICTSVTPGEPQVLLG--KDKAFTYDFVFDLD 57
+ +GD +KV VRIRP + +G ++C SV L + K FT+D V D+D
Sbjct: 21 SNEGDA-IKVFVRIRPPAERSGSADGEQNLCLSVLSSTSLRLHSNPEPKTFTFDHVADVD 79
Query: 58 TWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTM-GTGFDMATSEEEQGIIPRA 116
T QE +++T ++E C GYN T+ AYGQTG+GKT+TM G S +G+IPR+
Sbjct: 80 TTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIPRS 139
Query: 117 IAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKI 176
+LF I K +A AG F F+E+YNE+I DL DS + + +
Sbjct: 140 FEYLFSLIDREKEKAG----AGKSFLCKCSFIEIYNEQIYDLLDSAS--------AGLYL 187
Query: 177 HEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQM 236
E G++ G +++ S E Q L G +R AST MN +SSRSHA+FTI + M
Sbjct: 188 REHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESM 247
Query: 237 RMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISI 296
+ +VN T+ + VDLAGSER K T A G R KE +I
Sbjct: 248 EKSNE--IVN-----------------IRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNI 288
Query: 297 NCGLLALGNVISALGDQSK-KVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFM 355
N L LG VI+AL D K HV YRDSKLT LL+DSLGGN++T +IA V P R F
Sbjct: 289 NRSLSCLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFG 348
Query: 356 ETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKR-----VIG 410
ETL+TL +A RA+ IKNK VVN+D T +S L+AE+ RL+ +L E +G+ +
Sbjct: 349 ETLSTLNFAQRAKLIKNKAVVNED-TQGNVSQLQAEVKRLKEQLAELASGQTPPESFLTR 407
Query: 411 EDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDG 470
+ Y + F+E + K K+ QE I +VTQL ++ L K
Sbjct: 408 DKKKTNYMEYFQEAMLFFK---------KSEQEKKSLI-EKVTQL--EDLTLKKEKFIQS 455
Query: 471 NEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSP 530
N+ I ++ I +E+L + SR G P
Sbjct: 456 NKMIVKFREDQIIRLEKLHKE---------------SRG--------GFLP--------- 483
Query: 531 ASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDEN----- 585
E+ ++ + +++ L++ + E + AK EN +EN
Sbjct: 484 ----EEQDRLLSELRNEIQTLRE----------QIEHHPRVAKYAMENHSLREENRRLRL 529
Query: 586 -EAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIE 644
E + +E D + E + E SG E+S ++ + F C
Sbjct: 530 LEPVKRAQEMDAQTIAKLE--KAFSEISGMEKS--------DKNQQGFSPKAQKEPCLFA 579
Query: 645 IKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNL------------ 692
+KL +L Q L K +YEE + R QLE + LQ+L
Sbjct: 580 NTEKLKAQLLQIQTELNNSKQEYEE----FKELTRKRQLELESELQSLQKANLNLENLLE 635
Query: 693 STMECYTEE--KANKIKADY-------EKRLREMNRDLQKLQAAQKEHARL-LKNQSRYE 742
+T C +E + NKI A+ K + +R + KL L +N S +
Sbjct: 636 ATKACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILD 695
Query: 743 RELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRN-REIAQLKKEQRRQEFQIRAL 801
++ ++A A+ +++R Q++ ++ K + E LK +Q + + +
Sbjct: 696 NDILNEPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHST 755
Query: 802 ESQKR-QQEMVLRRKTQE--VSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSE 858
+ Q+ E + K QE +S L L K + E LK + D V + E
Sbjct: 756 QMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHD--LRVVLHSADKE 813
Query: 859 AESGARSVSSIVRQWNRKINHFLGDHPAPTV---NGTRPARKKFQKKGASQ----SFSKA 911
S SS ++ N H + N K + K Q + +
Sbjct: 814 LSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEI 873
Query: 912 ARLKWQSLERRIIDIVMQRMTIVN--------LEADMERLIK-----------KREELFL 952
+ + L R + + + T+ + LEA+ ER K +E+
Sbjct: 874 MKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILK 933
Query: 953 LQEALRRKRERLQAESPEEEKGLQELAEEI---EVLAANIDYINDGITDCQATIV-QLEE 1008
+ EA+R+++++ A+ ++ +Q+L E + E + ++++ D A ++ Q++E
Sbjct: 934 VLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQE 993
Query: 1009 TKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEGRLRQTDMA 1068
+ + ++ L + ++ L + + + ++E I L+ LR ++
Sbjct: 994 LRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILS 1053
Query: 1069 GSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEE 1109
+ +L + L A A +L L ++ +G + +E
Sbjct: 1054 EDIERDMLCEDL---AHATEQLNMLTEASKKHSGLLQSAQE 1091
Score = 62.8 bits (151), Expect = 3e-09
Identities = 105/504 (20%), Positives = 228/504 (45%), Gaps = 54/504 (10%)
Query: 345 ACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQ---ISALRAEIARLQMELME 401
AC+ S D ++ + + +RN++N N+ S + L AE R ++
Sbjct: 861 ACLQDS-YDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQ 919
Query: 402 YKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEAN 461
++ K ++ + + +E QKE ++ +Q+ +++ L +++
Sbjct: 920 FEEDKENSSKEILKVLEAVRQEK---QKETAKCEQQMAKVQKLEESL------LATEKVI 970
Query: 462 LLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASP 521
L K+ D ++ + A + N +I+ELRT + E ++L++ L + + +L
Sbjct: 971 SSLEKSRDSDKKVVADLMN---QIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDRE 1027
Query: 522 AAPAFGGSPASSMEDASEVIRRA--KQDLER---LKKKEVRQRRKSPEKEAFKKRAKLQQ 576
+ + D E +R +D+ER + + + EA KK + L Q
Sbjct: 1028 ESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQ 1087
Query: 577 ENSEETDENEA--EEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDS-DPEEKEV--N 631
EE + EA +E + + ++ E E+ + + + E ++DS + DP+ + +
Sbjct: 1088 SAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPH 1147
Query: 632 FQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEE-------KLILLQNKIRDTQ-- 682
FQ LA L +E +++ I++ S+ L+ L + E +++ ++ ++R+ +
Sbjct: 1148 FQTHLAKL---LETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENL 1204
Query: 683 -LERDRVLQNLSTMECYTEE-KANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSR 740
LE ++++ ++ ++ K K +D + + D Q+L+ Q+E + +S+
Sbjct: 1205 RLESQQLIEKNWLLQGQLDDIKRQKENSD------QNHPDNQQLKNEQEESIKERLAKSK 1258
Query: 741 YERELKKLQAEVAEMKKA---KVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQ 797
E+ K++A++ E++ A K +M +E +R + +E+K +E KEQ R + +
Sbjct: 1259 IVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQE-----KEQLRSKLE 1313
Query: 798 IRALESQKRQQEMVLRRKTQEVSA 821
E ++ QEM + RK E A
Sbjct: 1314 EMYEERERTSQEMEMLRKQVECLA 1337
Score = 52.8 bits (125), Expect = 3e-06
Identities = 105/506 (20%), Positives = 206/506 (40%), Gaps = 86/506 (16%)
Query: 278 ERLKRTGATGERAKEGISINCGLLALGNVISALG---DQSKKVVHVPYRDSKLTRLLQDS 334
E+ K T ++ + + LLA VIS+L D KKVV + L +Q+
Sbjct: 941 EKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVV------ADLMNQIQE- 993
Query: 335 LGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIK-NKVVVNQDKTSQQISALRAEIA 393
+ S + ET++TLK + N K N +V+++++ I +I
Sbjct: 994 ------------LRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVDIL 1041
Query: 394 RLQMELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVT 453
L+ L R++ ED E ML ++ ++ + EA
Sbjct: 1042 DLKETLR-----LRILSED---------IERDMLCEDLAHATEQLNMLTEA--------- 1078
Query: 454 QLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSR---AS 510
S++ + LL A + ALIQ ++ + + ++ + + R L ++
Sbjct: 1079 ---SKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSA 1135
Query: 511 ARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKK-----EVRQRRKSPEK 565
A P S P + E E R +K LE L K EV+ K
Sbjct: 1136 AEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMK 1195
Query: 566 EAFKKRAKLQQENSEETDEN--------EAEEEEEERDESGCEEEEGREDEDEDSGSEES 617
E ++ L+ E+ + ++N + + ++E D++ + ++ + +++E +E
Sbjct: 1196 EQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESI--KER 1253
Query: 618 LVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNK 677
L S E+ + +ADL ++ + K+ + + R QTL+ + ++ L++K
Sbjct: 1254 LAKSKI--VEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSK 1311
Query: 678 IRDTQLERDRVLQNLSTM----ECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHAR 733
+ + ER+R Q + + EC EE + + +++ +Q + +KE+ R
Sbjct: 1312 LEEMYEERERTSQEMEMLRKQVECLAEENGKLVGH------QNLHQKIQYVVRLKKENVR 1365
Query: 734 LLKNQSRYERELKKLQAEVAEMKKAK 759
L + E +KL+AE +K+ K
Sbjct: 1366 LAE-------ETEKLRAENVFLKEKK 1384
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 270 bits (690), Expect = 8e-72
Identities = 245/925 (26%), Positives = 421/925 (45%), Gaps = 143/925 (15%)
Query: 6 DCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYS 65
+C +KV R RP E + G + G+ V++G K + +D VF +T QEQ+Y
Sbjct: 7 ECSIKVLCRFRPLNQAEILRGDKFIP-IFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYH 64
Query: 66 TCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIA 125
C ++++ GYN T+ AYGQT +GKT+TM + GIIPR +F I
Sbjct: 65 ACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLH---DPQLMGIIPRIARDIFNHIY 121
Query: 126 ERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIY 185
EF + + E+Y ++I DL D T+ +N+ +HED N +
Sbjct: 122 SMDENL--------EFHIKVSYFEIYLDKIRDLLDVTK--------TNLSVHEDKNRVPF 165
Query: 186 TTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLV 245
G T R + S EE++ + +G +R A T MN SSRSH+IF I++ Q M T+
Sbjct: 166 VKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETE---- 221
Query: 246 NEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGN 305
+ L+ K + VDLAGSE++ +TGA G E +IN L ALGN
Sbjct: 222 -----------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGN 264
Query: 306 VISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYAN 365
VISAL + +K +VPYRDSK+TR+LQDSLGGN +T M C SPS + ET +TL +
Sbjct: 265 VISALAEGTKS--YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQ 322
Query: 366 RARNIKNKVVVNQDKTSQQ-----------ISALRAEIARLQMELMEYKAG------KRV 408
RA+ IKN VN + T++Q A + IA+L+ EL ++ G +R+
Sbjct: 323 RAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERL 382
Query: 409 IGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAG 468
GE+ A G ++L E + + +R+ + Q+ + I QL ++
Sbjct: 383 AGEEAALG-AELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKD--------- 432
Query: 469 DGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGG 528
D LI+ +++ + L+ + NE ++R LS
Sbjct: 433 DEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQ------------------ 474
Query: 529 SPASSMEDASEVIRRAKQDLERL------KKKEVRQRRKSPEKEAFKKRAKLQQENSEET 582
S + A + ++ Q LE L K +EV ++ + + + K+ S E+
Sbjct: 475 ---SENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLES 531
Query: 583 DENEAEEEEEERDESGCEEEEG-REDEDEDS-----GSEESLVDSDSDPEEKEVNFQADL 636
+ +E + + E G +D E S G + V+ EE+ + +
Sbjct: 532 ELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYI 591
Query: 637 ADLTCEIEIKQKLIDELENSQ----RRL----------QTLKHQYEEKLILLQNKIRDTQ 682
+ + E++ K +LEN Q R++ Q L Q+E K+ L ++ +
Sbjct: 592 SKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVE 651
Query: 683 LERDRVLQNLSTMECYTEEKANKIKAD---YEKRLREMNRDLQKLQAAQKE-HARLLKNQ 738
L++ + ++ ++ ++ K++A +E L++ D Q +K ++ ++
Sbjct: 652 LKKRHLEESYDSL----SDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHR 707
Query: 739 SRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQI 798
+ R+L +L+ E+ E +K + ++++ Q+ +L K + +LK E+ + ++
Sbjct: 708 EAHHRQLARLRDEINEKQKT----IDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKL 763
Query: 799 RAL------ESQKRQQ----EMVLRRKTQEVSALRRL-AKPMSERVAGRAGLKPPMLDSG 847
+ L Q +Q E + R+ Q + LR+L + ++ RV A ++P DSG
Sbjct: 764 QELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPE--DSG 821
Query: 848 AEVSASTTSSEAESGARSVSSIVRQ 872
S S E+ ++ + +Q
Sbjct: 822 GIHSQKQKISFLENNLEQLTKVHKQ 846
Score = 53.5 bits (127), Expect = 2e-06
Identities = 114/542 (21%), Positives = 234/542 (43%), Gaps = 47/542 (8%)
Query: 457 SQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYS 516
++ N L+ G+ A+ ++Y+ + T++L+ +++ + R ++ + S Y+
Sbjct: 252 AKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQ-DSLGGNCRTTMFICCSPSSYN 310
Query: 517 LGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSP-EKEAFKKRAKLQ 575
+ + FG A ++++ + V + E+ KKK +++ K+ +KE AKL+
Sbjct: 311 DAETKSTLMFG-QRAKTIKNTASV--NLELTAEQWKKKYEKEKEKTKAQKETI---AKLE 364
Query: 576 QENSE-ETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQA 634
E S EN E E +E+ G E +E ++ S + PEE++ ++
Sbjct: 365 AELSRWRNGENVPETERLAGEEAAL----GAELCEETPVNDNSSIVVRIAPEERQ-KYEE 419
Query: 635 DLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLST 694
++ L +++ K DE+ + ++ LK Q ++ LL + T+ + ++V + LS
Sbjct: 420 EIRRLYKQLDDKD---DEINQQSQLIEKLKQQMLDQEELLVS----TRGDNEKVQRELSH 472
Query: 695 MECYTEEKANKIK----------ADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERE 744
++ + +++K +Y+++ +E+ Q+ Q E ++ + E E
Sbjct: 473 LQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESE 532
Query: 745 LKKLQAEVAEMKKAKVA-----LMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIR 799
L++LQ EV+ ++ ++A LMK + E E K EI+ +E EF +
Sbjct: 533 LQRLQ-EVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEE----EFTVA 587
Query: 800 ALESQKRQQEM--VLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSS 857
L K + E+ V++R Q + + M V GR +L S E + +
Sbjct: 588 RLYISKIKSEVKSVVKRCRQLENLQVECHRKME--VTGRELSSCQLLISQHEAKIRSLTE 645
Query: 858 EAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQ 917
+S + ++ + TV+ K+ + A + KA L+ +
Sbjct: 646 YMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADE-VKKALELQME 704
Query: 918 S-LERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQ 976
S E + R I + ++ L ++L L E L+ E+L++E E+ LQ
Sbjct: 705 SHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQ 764
Query: 977 EL 978
EL
Sbjct: 765 EL 766
Score = 50.1 bits (118), Expect = 2e-05
Identities = 113/531 (21%), Positives = 214/531 (40%), Gaps = 93/531 (17%)
Query: 338 NSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQM 397
N + ++ ++P +R KY R + ++ D+ +QQ S L ++ + +
Sbjct: 400 NDNSSIVVRIAPEERQ--------KYEEEIRRLYKQLDDKDDEINQQ-SQLIEKLKQQML 450
Query: 398 ELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMS 457
+ E R E + RE + LQ EN A + VK + +A++ + Q
Sbjct: 451 DQEELLVSTRGDNEK-------VQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQ 503
Query: 458 Q-----EANLLLAKAGDGNEAIGALIQNYIREIEEL--RTKLLESEAMNESLRRSLSRAS 510
+ + N LL A +++ ++ ++E+ + +E +N L + LS S
Sbjct: 504 EVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLN-GLMKDLSEFS 562
Query: 511 A-------RSPYSL-GASPAAPAFGGSPASSME-DASEVIRRAKQDLERL-----KKKEV 556
+ P + GA S ++ + V++R +Q LE L +K EV
Sbjct: 563 VIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQ-LENLQVECHRKMEV 621
Query: 557 RQRRKSP------EKEA-------FKKRAKLQQENSEETDENEAEEEEEERDESGCEEEE 603
R S + EA + + +L++ + EE+ ++ ++E + + + E
Sbjct: 622 TGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVA 681
Query: 604 GREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQT- 662
++ E + ++E + E LA L EI KQK IDEL++ ++LQ
Sbjct: 682 LKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLE 741
Query: 663 ----------LKHQYEEKLILLQNKI----RDTQLERD---------RVLQNLSTM-ECY 698
LK + EK LQ R Q ++D R LQ L + + +
Sbjct: 742 LEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLF 801
Query: 699 TEEKANKIKADYEKRLRE---MNRDLQK-------LQAAQKEHARLLKNQSRYERELKKL 748
++ ++K E + ++ QK L+ K H +L+++ + EL KL
Sbjct: 802 VQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKL 861
Query: 749 QAEV---AEMKKAKVALMKQMRE---EQQRRRLVETKRNREIAQLKKEQRR 793
+ + AE KA +K+ +E + +RR E R +E + K +R
Sbjct: 862 EKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKR 912
Score = 33.5 bits (75), Expect = 1.7
Identities = 68/297 (22%), Positives = 114/297 (38%), Gaps = 44/297 (14%)
Query: 896 RKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQE 955
R K K AS + A + E+ Q+ TI LEA++ R + E E
Sbjct: 323 RAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRW--RNGENVPETE 380
Query: 956 ALRRKRERLQAESPEEE--------------KGLQELAEEIEVLAANIDYINDGITDCQA 1001
L + L AE EE + Q+ EEI L +D +D I
Sbjct: 381 RLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQ 440
Query: 1002 TIVQLEETKEELDSTDTSVVISSCSLAEARLL--LDNFLKASIDKGLQVAQKEAQIRLLE 1059
I +L++ + LD + V + R L L + A+ D+ +V Q ++ +
Sbjct: 441 LIEKLKQ--QMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNY 498
Query: 1060 GRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYA---------STDEEI 1110
+ Q S QN LL+D L +K L++ + +Q+ +G+ +++
Sbjct: 499 DQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDL 558
Query: 1111 SEFS--------------EGSFSQSFTM-KGSTSHDDFKFKSEPKLSAQMKAVSAEC 1152
SEFS G+ + FT+ + S + KS K Q++ + EC
Sbjct: 559 SEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVEC 615
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 267 bits (683), Expect = 5e-71
Identities = 238/914 (26%), Positives = 411/914 (44%), Gaps = 106/914 (11%)
Query: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
MA +C +KV R RP E + G G+ V++G+ K + +D V +T Q
Sbjct: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFK-GDETVVIGQGKPYVFDRVLPPNTTQ 59
Query: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
EQ+Y+ C ++++ EGYN T+ AYGQT +GKT+TM + GIIPR +
Sbjct: 60 EQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH---DPQLMGIIPRIAHDI 116
Query: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
F I EF + + E+Y ++I DL D ++ +N+ +HED
Sbjct: 117 FDHIYSMDENL--------EFHIKVSYFEIYLDKIRDLLDVSK--------TNLAVHEDK 160
Query: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
N Y G T R + S EE++ + +G +R A T MN SSRSH+IF I++ Q + T
Sbjct: 161 NRVPYVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVET 220
Query: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
+ + L+ K + VDLAGSE++ +TGA G E +IN L
Sbjct: 221 E---------------------KKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSL 259
Query: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
ALGNVISAL + +K HVPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +T
Sbjct: 260 SALGNVISALAEGTK--THVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKST 317
Query: 361 LKYANRARNIKNKVVVN-----------QDKTSQQISALRAEIARLQMELMEYKAGKRVI 409
L + RA+ IKN V VN +K ++ L+ I L+MEL ++ G+ V
Sbjct: 318 LMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVP 377
Query: 410 GEDGAEGYSDLFRE---------------NAMLQKENGALRLRVKAMQEAIDAINNRVTQ 454
++ E + +E + ++ +D ++ + Q
Sbjct: 378 EDEQISAKDQKNLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEINQ 437
Query: 455 LMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARS- 513
SQ A L + D +E + + ++Y + EEL +E+EA + ++ L +
Sbjct: 438 -QSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAV 496
Query: 514 PYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAK 573
Y + + + E A + E + +E+ +K E K
Sbjct: 497 NYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEILNLLLK 556
Query: 574 LQQENSEETDENEAEEEEEERDESGCEEEE---GREDEDEDSGSEESLVDSDSDPEEKEV 630
E N+ + D +G EEE R + +SLV+ E ++
Sbjct: 557 DLGEIGGIIGTNDV---KTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQM 613
Query: 631 NFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQ 690
+ + E+ Q LI + E + L E+K R + +D + +
Sbjct: 614 DSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKR-------RQLEESQDSLSE 666
Query: 691 NLSTMECYTEEKANKIK-ADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQ 749
L+ + +EK +++ D EK +D ++++ A ++ ++ ++ ++++L +L+
Sbjct: 667 ELAKLR--AQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQ--QMESHREAHQKQLSRLR 722
Query: 750 AEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIR--ALESQKRQ 807
E+ E +K ++ ++R+ Q+ +L + K + + +LK E + +E ++ L + KR+
Sbjct: 723 DEIEEKQK----IIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKRE 778
Query: 808 Q--------EMVLRRKTQEVSALRRL-AKPMSERVAGRAGLKPPMLDSGAEVSASTTSSE 858
Q E + R+ Q + LR+L + ++ RV L D G + S
Sbjct: 779 QAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDND--DGGGSAAQKQKISF 836
Query: 859 AESGARSVSSIVRQ 872
E+ ++ + +Q
Sbjct: 837 LENNLEQLTKVHKQ 850
Score = 69.3 bits (168), Expect = 3e-11
Identities = 112/479 (23%), Positives = 198/479 (41%), Gaps = 55/479 (11%)
Query: 411 EDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDG 470
ED L E A + + +QE + R T+++ NLLL G+
Sbjct: 506 EDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQKKRATEIL----NLLLKDLGEI 561
Query: 471 NEAIGALIQNYIREI-----EELRTKLLESEAMNESLR------RSLSRASARSPYSLGA 519
IG + ++ EE L M ++ + L A S + A
Sbjct: 562 GGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNRSKQLESAQMDSNRKMNA 621
Query: 520 SPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENS 579
S A S E + + Q++E+ K++++ + + S +E K RA QE
Sbjct: 622 SERELAACQLLISQHEAKIKSLTDYMQNMEQ-KRRQLEESQDSLSEELAKLRA---QEKM 677
Query: 580 EETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADL 639
E + E+E R +D +E + E ++S + +K+ L+ L
Sbjct: 678 HEVSFQDKEKEHLTR----------LQDAEEMKKALEQQMESHREAHQKQ------LSRL 721
Query: 640 TCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYT 699
EIE KQK+IDE+ + ++LQ +EKL NK++ ER+ L+ L +
Sbjct: 722 RDEIEEKQKIIDEIRDLNQKLQL----EQEKLSSDYNKLKIEDQEREMKLEKLLLL---- 773
Query: 700 EEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAK 759
+K + + D + ++R+LQ L +K + L + + EL + +K K
Sbjct: 774 NDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQK 833
Query: 760 VALMKQMREE--QQRRRLVETKRNR--EIAQLKKEQRRQEFQIRALESQ-KRQQEMVLR- 813
++ ++ E+ + ++LV + E+ +L+K R +++ALES K +E +R
Sbjct: 834 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 893
Query: 814 --RKTQEVSALRRL--AKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSS 868
R QEV ++ AK M+ R KP + G ++S T+ A G SS
Sbjct: 894 RKRYQQEVDRIKEAVRAKNMARRAHSAQIAKP--IRPGHYPASSPTAVHAIRGGGGSSS 950
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 266 bits (680), Expect = 1e-70
Identities = 247/912 (27%), Positives = 412/912 (45%), Gaps = 139/912 (15%)
Query: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
MA +C +KV R RP L++ ++ + GE V++ K + +D VF T Q
Sbjct: 1 MADLAECNIKVMCRFRP-LNESEVNRGDKYIAKFQGEDTVVIAS-KPYAFDRVFQSSTSQ 58
Query: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
EQ+Y+ C K+++ EGYN T+ AYGQT +GKT+TM E GIIPR + +
Sbjct: 59 EQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH---DPEGMGIIPRIVQDI 115
Query: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
F I EF + + E+Y ++I DL D ++ +N+ +HED
Sbjct: 116 FNYIYSMDENL--------EFHIKVSYFEIYLDKIRDLLDVSK--------TNLSVHEDK 159
Query: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
N Y G T R + S +E++ + +G +R A T MN SSRSH+IF I++ Q T
Sbjct: 160 NRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQT 219
Query: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
+ + L+ K + VDLAGSE++ +TGA G E +IN L
Sbjct: 220 E---------------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSL 258
Query: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
ALGNVISAL + S +VPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +T
Sbjct: 259 SALGNVISALAEGS---TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKST 315
Query: 361 LKYANRARNIKNKVVVNQDKTSQQ-----------ISALRAEIARLQMELMEYKAGKRV- 408
L + RA+ IKN V VN + T++Q LR I L+ EL ++ G+ V
Sbjct: 316 LLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVP 375
Query: 409 IGE--DGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAK 466
I E D + + F + + N + + DA + +E L +
Sbjct: 376 IDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRK----CEEEIAKLYKQ 431
Query: 467 AGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAF 526
D +E I Q +E+L+T++L+ E + S RR A + A
Sbjct: 432 LDDKDEEINQQSQ----LVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDA---- 483
Query: 527 GGSPASSMEDASEVIRRAKQDLERL------KKKEVRQRRKSPE---KEAFKKRAKLQQE 577
S E+ EV+ Q LE L K +EV + K E E +K A L
Sbjct: 484 ------SKEEVKEVL----QALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASI 533
Query: 578 NSEETDENEAEEEEEER----------DESGCEEEEGREDEDEDSGSEESLVDSDSDPEE 627
++E E +++R D + G D + G+ ++D E
Sbjct: 534 DAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGT--GMID------E 585
Query: 628 KEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLE--- 684
+ + ++ + E++ K +LE++Q + E++L Q +I + +
Sbjct: 586 EFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKS 645
Query: 685 RDRVLQNLSTMECYTEEKANKIKADY-----EKRLREMNRD-LQKLQAA----QKEHARL 734
LQN+ + EE + + + ++++ EM ++ L K+Q A Q ++
Sbjct: 646 LTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQI 705
Query: 735 LKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLK---KEQ 791
++ +++++ L+ EV +AK L+ ++++ Q+ L + + E +LK +E+
Sbjct: 706 QSHRETHQKQISSLRDEV----EAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEK 761
Query: 792 RRQEFQIRALESQKRQQEMVLR----RKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSG 847
R+ ++ ++ ++ Q L+ +E+ L L K + +A R +
Sbjct: 762 SRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATR-------VKKS 814
Query: 848 AEVSASTTSSEA 859
AE+ + T A
Sbjct: 815 AEIDSDDTGGSA 826
Score = 43.9 bits (102), Expect = 0.001
Identities = 100/505 (19%), Positives = 200/505 (39%), Gaps = 61/505 (12%)
Query: 679 RDTQLERDRVLQNLSTMECYTEEKANKIKA----------DYEKRLREMNRDLQKLQAAQ 728
+D L D+ + + +T+ + K + D ++ + + ++ ++KL+
Sbjct: 394 KDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQM 453
Query: 729 KEHARLL----KNQSRYERELKKLQAE----VAEMKKAKVALMKQMREEQQRRRLVETKR 780
+ LL ++Q + EL +LQAE E+K+ AL + Q+ + VE K
Sbjct: 454 LDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDK- 512
Query: 781 NREIAQLKKEQRRQEFQIRALESQ-KRQQEMVLRRKTQEVSALRRLAKPMSER--VAGRA 837
+E L E ++ + +++++ ++ +EM +K + + L K ++E G
Sbjct: 513 TKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNN 572
Query: 838 GLKPP----MLDSG---AEVSASTTSSEAES---GARSVSSIVRQWNRKINHFLGDHPAP 887
+K P M+D A + S SE ++ + + S + N+K+ + A
Sbjct: 573 DVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAAC 632
Query: 888 TVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKR 947
+ ++ K Q+ + R +S++ ++V R E + E L K +
Sbjct: 633 QLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQ 692
Query: 948 EELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLE 1007
E + +++Q+ +K + L +E+E A I + D +L
Sbjct: 693 TA----NEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLR 748
Query: 1008 ETKEELDSTDTSVVISSCSLAEARLLLDNFLKASID-KGL-QVAQKEAQIRLLEGRLRQT 1065
E+L +TD S L E ++ D +A D KGL + KE Q +L
Sbjct: 749 VEHEKLKATDQE---KSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQ 805
Query: 1066 DMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMK 1125
D+A + +D+ G A+ ++IS F E + Q +
Sbjct: 806 DLATRVKKSAEIDS------------------DDTGGSAAQKQKIS-FLENNLEQLTKVH 846
Query: 1126 GSTSHDDFKFKSE-PKLSAQMKAVS 1149
D+ + E PKL +++A +
Sbjct: 847 KQLVRDNADLRCELPKLEKRLRATA 871
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 263 bits (673), Expect = 8e-70
Identities = 193/587 (32%), Positives = 294/587 (50%), Gaps = 71/587 (12%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD-------KAFTYDFVFDLDTWQE 61
VKV VR RP +EK SV + + K K FT+D VF ++ Q
Sbjct: 15 VKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQL 74
Query: 62 QIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLF 121
+Y+ +I+ EGYN T+ AYGQTG GKT+TM + E +GIIP + AH+F
Sbjct: 75 DVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTME---GVRAIPELRGIIPNSFAHIF 131
Query: 122 GGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDAN 181
G IA+ + F V +LE+YNEE+ DL + + +++ E +
Sbjct: 132 GHIAKAE--------GDTRFLVRVSYLEIYNEEVRDLLG-------KDQTQRLEVKERPD 176
Query: 182 GGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQ 241
G+Y +++ ++++ +++ + + G +R+ +T MN SSRSHAIFTI + C++
Sbjct: 177 VGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITI----ECSE 232
Query: 242 PDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLL 301
+ DG K H VDLAGSER +TGATG+R KE IN L
Sbjct: 233 KGI---------DGN-----MHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLS 278
Query: 302 ALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTL 361
LGNVISAL D K HVPYR+SKLTRLLQDSLGGNS+T+M A + P+D ++ ET++TL
Sbjct: 279 TLGNVISALVDG--KSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTL 336
Query: 362 KYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDLF 421
+YANRA+NIKNK +N+D + + EI L+ +L E G+ + G D + D
Sbjct: 337 RYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEE---GEEISGSDISGSEEDDD 393
Query: 422 RENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNY 481
E + E+G R + + ++ + + +E L K E +N
Sbjct: 394 EEGEV--GEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLDMEEEE-----RNK 446
Query: 482 IR-EIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV 540
R E+E+ LL+++ ++SL LS + G + E+ ++
Sbjct: 447 ARAELEKREKDLLKAQQEHQSLLEKLSALEKK----------VIVGGVDLLAKAEEQEKL 496
Query: 541 IRRAKQDLERLKKKEVRQRRKSPEKEAFK-----KRAKLQQENSEET 582
+ + +LE +K+ + RR+ EKE + K LQ+E +T
Sbjct: 497 LEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKT 543
Score = 60.5 bits (145), Expect = 1e-08
Identities = 67/285 (23%), Positives = 127/285 (44%), Gaps = 50/285 (17%)
Query: 466 KAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPA 525
KA + AL++ + +EIEEL+ KL E E ++
Sbjct: 348 KARINEDPKDALLRQFQKEIEELKKKLEEGEEIS-------------------------- 381
Query: 526 FGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDEN 585
GS S E+ + +D E+ KK+ + ++ SP+K + +AK+ +E +
Sbjct: 382 --GSDISGSEEDDDEEGEVGEDGEKRKKRRGK-KKVSPDK-MIEMQAKIDEERKALETKL 437
Query: 586 EAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEI 645
+ EE EER+++ E E+ +D + +SL++ S E+K + DL + E
Sbjct: 438 DMEE--EERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVI---VGGVDLLAKAEE 492
Query: 646 KQKLID----ELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEE 701
++KL++ ELE ++R + L+ + EEK + ER + + ++++ +
Sbjct: 493 QEKLLEESNMELEERRKRAEQLRRELEEK-----------EQERLDIEEKYTSLQEEAQG 541
Query: 702 KANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELK 746
K K+K + + + Q Q+E LL+N + REL+
Sbjct: 542 KTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRELR 586
Score = 33.5 bits (75), Expect = 1.7
Identities = 38/196 (19%), Positives = 83/196 (42%), Gaps = 30/196 (15%)
Query: 655 NSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRL 714
N + TL++ K I +NK R + +D +L+ +++ ++K E+
Sbjct: 328 NYDETISTLRYANRAKNI--KNKARINEDPKDALLRQF-------QKEIEELKKKLEEGE 378
Query: 715 REMNRDLQKLQAAQKEHARLLKN-QSRYERELKK---------LQAEVAEMKKAKVALMK 764
D+ + E + ++ + R +R KK +QA++ E +KA +
Sbjct: 379 EISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALETKLD 438
Query: 765 QMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALE-----------SQKRQQEMVLR 813
EE+ + R KR +++ + ++E + ++ ALE ++ +QE +L
Sbjct: 439 MEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLE 498
Query: 814 RKTQEVSALRRLAKPM 829
E+ R+ A+ +
Sbjct: 499 ESNMELEERRKRAEQL 514
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 262 bits (669), Expect = 2e-69
Identities = 192/582 (32%), Positives = 291/582 (50%), Gaps = 71/582 (12%)
Query: 9 VKVAVRIRPQLSKEKIEGCH--ICTSVTPGEPQVLLGKD------KAFTYDFVFDLDTWQ 60
V+V VR RP KEK + V G+ V K K FT+D V+D + Q
Sbjct: 10 VRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAVYDWNAKQ 69
Query: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
++Y L++ +G+N T+ AYGQTG GKTYTM + E++G+IP + H+
Sbjct: 70 FELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTME---GIRGDPEKRGVIPNSFDHI 126
Query: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
F I+ R+Q Q ++ V A +LE+Y EEI DL ++ + +++ E
Sbjct: 127 FTHIS----RSQNQ-----QYLVRASYLEIYQEEIRDLL-------SKDQTKRLELKERP 170
Query: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
+ G+Y ++S + S +E+ + G +R+ +T MN SSRSHAIF I + C+
Sbjct: 171 DTGVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITI----ECS 226
Query: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
+ L DG E K + VDLAGSER +TGA GER KE IN L
Sbjct: 227 EVGL---------DG-----ENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSL 272
Query: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
ALGNVISAL D K H+PYRDSKLTRLLQDSLGGN++T+M+A V P+ + ETL T
Sbjct: 273 SALGNVISALVDG--KSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTT 330
Query: 361 LKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGEDGAEGYSDL 420
L+YANRA+NIKNK VN+D + + EIARL+ +L + G+R E EG
Sbjct: 331 LRYANRAKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGG-- 388
Query: 421 FRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQN 480
G + +E + +++ Q+ L + K A++++
Sbjct: 389 ---------SGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIEKR--------AIVED 431
Query: 481 YIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEV 540
+ EE L E E E LRR A G + + ++
Sbjct: 432 HSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKI 491
Query: 541 IRRAKQDL--ERLKKKEVRQRRKSPEKEAFKKR---AKLQQE 577
+ + +Q++ ++ +++E++Q+ +S ++E + + + LQQE
Sbjct: 492 LEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQE 533
Score = 53.5 bits (127), Expect = 2e-06
Identities = 59/265 (22%), Positives = 122/265 (46%), Gaps = 27/265 (10%)
Query: 531 ASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEE 590
A ++++ V K L R ++E+ + + EK + +R + ++ EEE
Sbjct: 337 AKNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEE 396
Query: 591 EEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLI 650
EEE +E EEEG D+ +D E+ E+ E+ +A + D + E K +L+
Sbjct: 397 EEEGEEG---EEEG--DDKDDYWREQQ--------EKLEIEKRAIVEDHSLVAEEKMRLL 443
Query: 651 DELENSQRRLQTLKHQYE---EKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIK 707
E E L+ K E K+ +++K+ + ++ + + + E+K +I
Sbjct: 444 KEKEKKMEDLRREKDAAEMLGAKIKAMESKL---LVGGKNIVDHTNEQQKILEQKRQEI- 499
Query: 708 ADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYEREL----KKLQAEVAEMKKAKVALM 763
A+ ++R RE+ Q++++ +E L + S ++E+ KKL+ ++++ K +
Sbjct: 500 AEQKRREREIQ---QQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIH 556
Query: 764 KQMREEQQRRRLVETKRNREIAQLK 788
E + R+ +E +N +LK
Sbjct: 557 DLQEEHIKERQELEQTQNELTRELK 581
Score = 51.2 bits (121), Expect = 8e-06
Identities = 58/298 (19%), Positives = 138/298 (46%), Gaps = 27/298 (9%)
Query: 530 PASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEE 589
P + + ++R ++++ RLK ++ +R K K+R E +E E EE
Sbjct: 344 PRVNEDPKDALLREFQEEIARLKA-QLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEE 402
Query: 590 EEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNF----QADLADLTCEIEI 645
EEE D+ +++ RE +++ + ++V+ S E+++ + + DL E +
Sbjct: 403 GEEEGDD---KDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDA 459
Query: 646 KQKLIDELENSQRRL-----QTLKHQYEEKLILLQ-------NKIRDTQLERDRVLQNLS 693
+ L +++ + +L + H E++ IL Q K R+ ++++ ++
Sbjct: 460 AEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEE 519
Query: 694 TMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVA 753
T+E +E + ++ + + + +++ + KLQA + E L + + +EL++ Q E+
Sbjct: 520 TLE--LKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELT 577
Query: 754 EMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMV 811
K K +++ +++ +++ NR ++E + I LE+Q+ + V
Sbjct: 578 RELKLKHLIIENFIPLEEKSKIM----NRAFFD-EEEDHWKLHPITRLENQQMMKRPV 630
Score = 35.0 bits (79), Expect = 0.59
Identities = 33/148 (22%), Positives = 71/148 (47%), Gaps = 12/148 (8%)
Query: 700 EEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAK 759
++K + + EK E ++ +E RLLK + + +L++ + + AEM AK
Sbjct: 408 DDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRR-EKDAAEMLGAK 466
Query: 760 VALMKQ---------MREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEM 810
+ M+ + ++++++E KR +EIA+ K+ +R + Q+ + + + + +
Sbjct: 467 IKAMESKLLVGGKNIVDHTNEQQKILEQKR-QEIAEQKRREREIQQQMESRDEETLELKE 525
Query: 811 VLRRKTQEVS-ALRRLAKPMSERVAGRA 837
QEV ++L K S+ A +A
Sbjct: 526 TYSSLQQEVDIKTKKLKKLFSKLQAVKA 553
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 260 bits (665), Expect = 7e-69
Identities = 160/400 (40%), Positives = 224/400 (56%), Gaps = 46/400 (11%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD-------KAFTYDFVFDLDTWQE 61
VKV VR RP +E+ C +V Q + K FT+D + +D E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 62 QIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLF 121
QIY+ L+EG EGYN T+ AYGQTG+GK++TM + ++GIIPRA H+F
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQ---GLPDPPSQRGIIPRAFEHVF 122
Query: 122 GGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDAN 181
+ Q +F V A +LE+YNE++ DL + DT+ + +++ E
Sbjct: 123 ESV---------QCAENTKFLVRASYLEIYNEDVRDLLGA----DTKQK---LELKEHPE 166
Query: 182 GGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQ 241
G+Y G++ +HS + ++ G +R+ T MN SSRSH+IFTI + +
Sbjct: 167 KGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISI-------E 219
Query: 242 PDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLL 301
V+E + K + VDLAGSER +TGATGER KE IN L
Sbjct: 220 MSAVDER-----------GKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLS 268
Query: 302 ALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTL 361
ALGNVISAL D K HVPYRDSKLTRLLQDSLGGN++T+M+AC+SP+D ++ ETL+TL
Sbjct: 269 ALGNVISALVDGRCK--HVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTL 326
Query: 362 KYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELME 401
+YANRA+NI+NK +N+D + + EI +L+ L +
Sbjct: 327 RYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAILTQ 366
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 260 bits (665), Expect = 7e-69
Identities = 160/400 (40%), Positives = 224/400 (56%), Gaps = 46/400 (11%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD-------KAFTYDFVFDLDTWQE 61
VKV VR RP +E+ C +V Q + K FT+D + +D E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 62 QIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLF 121
QIY+ L+EG EGYN T+ AYGQTG+GK++TM + ++GIIPRA H+F
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQ---GLPDPPSQRGIIPRAFEHVF 122
Query: 122 GGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDAN 181
+ Q +F V A +LE+YNE++ DL + DT+ + +++ E
Sbjct: 123 ESV---------QCAENTKFLVRASYLEIYNEDVRDLLGA----DTKQK---LELKEHPE 166
Query: 182 GGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQ 241
G+Y G++ +HS + ++ G +R+ T MN SSRSH+IFTI + +
Sbjct: 167 KGVYVKGLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISI-------E 219
Query: 242 PDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLL 301
V+E + K + VDLAGSER +TGATGER KE IN L
Sbjct: 220 MSAVDER-----------GKDHLRAGKLNLVDLAGSERQSKTGATGERLKEATKINLSLS 268
Query: 302 ALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTL 361
ALGNVISAL D K HVPYRDSKLTRLLQDSLGGN++T+M+AC+SP+D ++ ETL+TL
Sbjct: 269 ALGNVISALVDGRCK--HVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTL 326
Query: 362 KYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELME 401
+YANRA+NI+NK +N+D + + EI +L+ L +
Sbjct: 327 RYANRAKNIRNKPRINEDPKDALLREYQEEIKKLKAILTQ 366
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 253 bits (646), Expect = 1e-66
Identities = 243/836 (29%), Positives = 385/836 (46%), Gaps = 164/836 (19%)
Query: 5 GDCCVKVAVRIRPQLSKE--------------KIEGCHICTSVTPGEPQVLLGKDKAFTY 50
GD VKVAVRIRP +E K+ + T+++ G+ + G+ K F Y
Sbjct: 2 GDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDAR---GQPKVFAY 58
Query: 51 DFVF--------DLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFD 102
D F + Q+ ++ +++ F+GYNA + AYGQTG+GK+YTM
Sbjct: 59 DHCFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTM----- 113
Query: 103 MATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDST 162
M T+++ G+IPR + LF R Q++ FKV ++E+YNE++ DL D
Sbjct: 114 MGTADQP-GLIPRLCSGLF-------ERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDP- 164
Query: 163 RDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQS 222
+ R +K+ E + G Y G++ + S +++ + +G SRT A+T MN +S
Sbjct: 165 -----KGSRQTLKVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEES 219
Query: 223 SRSHAIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKR 282
SRSHA+F I L + E V K VDLAGSER +
Sbjct: 220 SRSHAVFKITLTHTLYDVKSGTSGEKV-----------------GKLSLVDLAGSERATK 262
Query: 283 TGATGERAKEGISINCGLLALGNVISALGDQS---KKVVHVPYRDSKLTRLLQDSLGGNS 339
TGA G+R KEG +IN L LG VISAL DQS K VPYRDS LT LL+DSLGGNS
Sbjct: 263 TGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNS 322
Query: 340 QTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMEL 399
+T M+A VSP+ ++ ETL+TL+YA+RA++I N VVN+D ++ I LR E+ +L+ +L
Sbjct: 323 KTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQL 382
Query: 400 MEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQE 459
+ +A K +D E L +E + +E LR + QE + + L S
Sbjct: 383 TKAEAMKSPELKDRLEESEKLIQEMTVTWEEK--LRKTEEIAQERQKQLESLGISLQSSG 440
Query: 460 ANLLLAKAGD---------GNEAIGALIQNYIRE---IEELRTKLLESEAMNESLRRSLS 507
K GD + A+ L+ Y++E I ++ ++ M +
Sbjct: 441 -----IKVGDDKCFLVNLNADPALNELLVYYLKEHTLIGSANSQDIQLCGMGILPEHCII 495
Query: 508 RASARSPYSLGASPAAPAF--GGSPASSME-DASEVIRRAKQDLERLKKKEVRQRRKSPE 564
++ L F G S +S ++ + I RL P+
Sbjct: 496 DITSEGQVMLTPQKNTRTFVNGSSVSSPIQLHHGDRILWGNNHFFRL---------NLPK 546
Query: 565 KEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSD 624
K KK+A+ + E+ + + +NE E+ D D DS SE S
Sbjct: 547 K---KKKAEREDEDQDPSMKNENSSEQ--------------LDVDGDSSSEVS------- 582
Query: 625 PEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLE 684
EVNF + A ++E+ K + + Q L +L+ Q+EE+ + + LE
Sbjct: 583 ---SEVNFNYEYA----QMEVTMKALGSNDPMQSILNSLEQQHEEE--------KRSALE 627
Query: 685 RDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERE 744
R R++ YE L ++ R L + +K++ R + S +
Sbjct: 628 RQRLM--------------------YEHELEQLRRRL----SPEKQNCRSMDRFSFHSPS 663
Query: 745 LKKLQAEVAEMKKAKV--ALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQI 798
++ + AE ++A + +LM+ +RE+ + L+ + N +L K R E+++
Sbjct: 664 AQQRLRQWAEEREATLNNSLMR-LREQIVKANLLVREANYIAEELDK---RTEYKV 715
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 238 bits (608), Expect = 3e-62
Identities = 209/685 (30%), Positives = 318/685 (46%), Gaps = 117/685 (17%)
Query: 9 VKVAVRIRPQLSKEKIEGCH-ICT------SVTPGEPQVLLGK-DKAFTYDFVFDLDTWQ 60
+KV R RP KE+ G I T VT P+ G+ K FT+D V+D + Q
Sbjct: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
Query: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTM-GTGFDMATSEEEQGIIPRAIAH 119
+Y V LI+ +G+N TV AYGQTG GKTYTM GT + E +G+IP A H
Sbjct: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVE----PELRGVIPNAFEH 126
Query: 120 LFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHED 179
+F I+ R+Q Q ++ V A +LE+Y EEI DL +++P R +++ E+
Sbjct: 127 IFTHIS----RSQNQ-----QYLVRASYLEIYQEEIRDLL--SKEPGKR-----LELKEN 170
Query: 180 ANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHL-CQMRM 238
G+Y ++S + + +E+ + G +R ST MN SSRSHAIF I + C R
Sbjct: 171 PETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERG 230
Query: 239 CTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTG-------------- 284
D + K + VDLAGSER + G
Sbjct: 231 SDGQDHIR-------------------VGKLNLVDLAGSERQNKAGPNTAGGAATPSSGG 271
Query: 285 ----------ATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDS 334
A GER KE IN L ALGNVI+AL + H+PYRDSKLTRLLQDS
Sbjct: 272 GGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALA--GNRSTHIPYRDSKLTRLLQDS 329
Query: 335 LGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIAR 394
LGGN++TIM+A + P+ + E+L+TL++ANRA+NIKNK VN+D + + EIAR
Sbjct: 330 LGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIAR 389
Query: 395 LQMELME---------YKAGKRVIGEDGAEGYSDLFRENAMLQKE----NGALRLRVKAM 441
L+ +L + K+ +R GY + A + +E N R +
Sbjct: 390 LKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPIL 449
Query: 442 QEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLL-ESEAMNE 500
+ A++ N L Q+ L E A IQ+ + E + KLL E E M E
Sbjct: 450 ESALE--KNMENYLQEQKERL---------EEEKAAIQDDRSLVSEEKQKLLEEKEKMLE 498
Query: 501 SLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDL--ERLKKKEVRQ 558
LRR + G + + +++ +Q++ ++ +++E++Q
Sbjct: 499 DLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQ 558
Query: 559 RRKSPEKEAFKKR---AKLQQENSEETD------------ENEAEEEEEERDESGCEEEE 603
++E + R LQQE +T + E +++ +E + EE
Sbjct: 559 EMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEE 618
Query: 604 GREDEDEDSGSEESLVDSDSDPEEK 628
+ ++ + + ++++ PEEK
Sbjct: 619 AQNEQTRELKLKYLIIENFIPPEEK 643
Score = 32.7 bits (73), Expect = 2.9
Identities = 33/133 (24%), Positives = 70/133 (52%), Gaps = 15/133 (11%)
Query: 695 MECYTEEKANKIKADYEKRLREMNRDL--QKLQAAQKEHARLLKNQSRYERELKKLQAEV 752
ME Y +E+ +++ EK + +R L ++ Q +E ++L++ R ++ + L A+
Sbjct: 457 MENYLQEQKERLEE--EKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKY 514
Query: 753 AEMK-KAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQR--RQEFQIRALESQK---- 805
M+ K + M ++++++E KR +EIA+ K+ +R +QE +R E+ +
Sbjct: 515 KAMESKLLIGGRNIMDHTNEQQKMLELKR-QEIAEQKRREREMQQEMMLRDEETMELRGT 573
Query: 806 ---RQQEMVLRRK 815
QQE+ ++ K
Sbjct: 574 YTSLQQEVEVKTK 586
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 238 bits (606), Expect = 5e-62
Identities = 176/488 (36%), Positives = 252/488 (51%), Gaps = 70/488 (14%)
Query: 6 DCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVL-----------LGKDKAFTYDFVF 54
D VKVAVR+RP +++ ++E C G VL K F +D+ F
Sbjct: 3 DTKVKVAVRVRP-MNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 55 -DLD-------TWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATS 106
+D QE ++ ++E F+GYNA + AYGQTG+GK+ F M
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKS------FSMMGH 115
Query: 107 EEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPD 166
E+ G+IPR LF I+ + +Q FKV ++E+YNE++ DL D
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQT-------FKVEVSYMEIYNEKVRDLLDP----- 163
Query: 167 TRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSH 226
+ R ++K+ E G Y G++ + S E++ + +G SRT A+T MN +SSRSH
Sbjct: 164 -KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSH 222
Query: 227 AIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGAT 286
A+F I + Q Q E V+ K VDLAGSER+ +TGA
Sbjct: 223 AVFNIIITQTLYDLQSGNSGEKVS-----------------KVSLVDLAGSERVSKTGAA 265
Query: 287 GERAKEGISINCGLLALGNVISALGDQSK---KVVHVPYRDSKLTRLLQDSLGGNSQTIM 343
GER KEG +IN L LG VIS+L DQ+ K VPYRDS LT LL+D+LGGNSQT M
Sbjct: 266 GERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSM 325
Query: 344 IACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYK 403
IA +SP+ ++ ETL+TL+YA+RA+ I N VVN+D ++ I LR E+ +L+ +L + +
Sbjct: 326 IATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAE 385
Query: 404 AGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLL 463
A K ++ E L +E + +E LR + QE R QL S +L
Sbjct: 386 AMKAPELKEKLEESEKLIKELTVTWEEK--LRKTEEIAQE-------RQRQLESMGISLE 436
Query: 464 LA--KAGD 469
++ K GD
Sbjct: 437 MSGIKVGD 444
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 238 bits (606), Expect = 5e-62
Identities = 176/488 (36%), Positives = 252/488 (51%), Gaps = 70/488 (14%)
Query: 6 DCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVL-----------LGKDKAFTYDFVF 54
D VKVAVR+RP +++ ++E C G VL K F +D+ F
Sbjct: 3 DTKVKVAVRVRP-MNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 55 -DLD-------TWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATS 106
+D QE ++ ++E F+GYNA + AYGQTG+GK+ F M
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKS------FSMMGH 115
Query: 107 EEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPD 166
E+ G+IPR LF I+ + +Q FKV ++E+YNE++ DL D
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQT-------FKVEVSYMEIYNEKVRDLLDP----- 163
Query: 167 TRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSH 226
+ R ++K+ E G Y G++ + S E++ + +G SRT A+T MN +SSRSH
Sbjct: 164 -KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSH 222
Query: 227 AIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGAT 286
A+F I + Q Q E V+ K VDLAGSER+ +TGA
Sbjct: 223 AVFNIIITQTLYDLQSGNSGEKVS-----------------KVSLVDLAGSERVSKTGAA 265
Query: 287 GERAKEGISINCGLLALGNVISALGDQSK---KVVHVPYRDSKLTRLLQDSLGGNSQTIM 343
GER KEG +IN L LG VIS+L DQ+ K VPYRDS LT LL+D+LGGNSQT M
Sbjct: 266 GERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSM 325
Query: 344 IACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYK 403
IA +SP+ ++ ETL+TL+YA+RA+ I N VVN+D ++ I LR E+ +L+ +L + +
Sbjct: 326 IATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAE 385
Query: 404 AGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLL 463
A K ++ E L +E + +E LR + QE R QL S +L
Sbjct: 386 AMKAPELKEKLEESEKLIKELTVTWEEK--LRKTEEIAQE-------RQRQLESMGISLE 436
Query: 464 LA--KAGD 469
++ K GD
Sbjct: 437 MSGIKVGD 444
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 238 bits (606), Expect = 5e-62
Identities = 176/488 (36%), Positives = 252/488 (51%), Gaps = 70/488 (14%)
Query: 6 DCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVL-----------LGKDKAFTYDFVF 54
D VKVAVR+RP +++ ++E C G VL K F +D+ F
Sbjct: 3 DTKVKVAVRVRP-MNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 55 -DLD-------TWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATS 106
+D QE ++ ++E F+GYNA + AYGQTG+GK+ F M
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKS------FSMMGH 115
Query: 107 EEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPD 166
E+ G+IPR LF I+ + +Q FKV ++E+YNE++ DL D
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQT-------FKVEVSYMEIYNEKVRDLLDP----- 163
Query: 167 TRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSH 226
+ R ++K+ E G Y G++ + S E++ + +G SRT A+T MN +SSRSH
Sbjct: 164 -KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSH 222
Query: 227 AIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGAT 286
A+F I + Q Q E V+ K VDLAGSER+ +TGA
Sbjct: 223 AVFNIIITQTLYDLQSGNSGEKVS-----------------KVSLVDLAGSERVSKTGAA 265
Query: 287 GERAKEGISINCGLLALGNVISALGDQSK---KVVHVPYRDSKLTRLLQDSLGGNSQTIM 343
GER KEG +IN L LG VIS+L DQ+ K VPYRDS LT LL+D+LGGNSQT M
Sbjct: 266 GERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSM 325
Query: 344 IACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYK 403
IA +SP+ ++ ETL+TL+YA+RA+ I N VVN+D ++ I LR E+ +L+ +L + +
Sbjct: 326 IATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAE 385
Query: 404 AGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLL 463
A K ++ E L +E + +E LR + QE R QL S +L
Sbjct: 386 AMKAPELKEKLEESEKLIKELTVTWEEK--LRKTEEIAQE-------RQRQLESMGISLE 436
Query: 464 LA--KAGD 469
++ K GD
Sbjct: 437 MSGIKVGD 444
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 238 bits (606), Expect = 5e-62
Identities = 176/488 (36%), Positives = 252/488 (51%), Gaps = 70/488 (14%)
Query: 6 DCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVL-----------LGKDKAFTYDFVF 54
D VKVAVR+RP +++ ++E C G VL K F +D+ F
Sbjct: 3 DTKVKVAVRVRP-MNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 55 -DLD-------TWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATS 106
+D QE ++ ++E F+GYNA + AYGQTG+GK+ F M
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKS------FSMMGH 115
Query: 107 EEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPD 166
E+ G+IPR LF I+ + +Q FKV ++E+YNE++ DL D
Sbjct: 116 AEQLGLIPRLCCALFKRISLEQNESQT-------FKVEVSYMEIYNEKVRDLLDP----- 163
Query: 167 TRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSH 226
+ R ++K+ E G Y G++ + S E++ + +G SRT A+T MN +SSRSH
Sbjct: 164 -KGSRQSLKVREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSH 222
Query: 227 AIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGAT 286
A+F I + Q Q E V+ K VDLAGSER+ +TGA
Sbjct: 223 AVFNIIITQTLYDLQSGNSGEKVS-----------------KVSLVDLAGSERVSKTGAA 265
Query: 287 GERAKEGISINCGLLALGNVISALGDQSK---KVVHVPYRDSKLTRLLQDSLGGNSQTIM 343
GER KEG +IN L LG VIS+L DQ+ K VPYRDS LT LL+D+LGGNSQT M
Sbjct: 266 GERLKEGSNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSM 325
Query: 344 IACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYK 403
IA +SP+ ++ ETL+TL+YA+RA+ I N VVN+D ++ I LR E+ +L+ +L + +
Sbjct: 326 IATISPAADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQAE 385
Query: 404 AGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLL 463
A K ++ E L +E + +E LR + QE R QL S +L
Sbjct: 386 AMKAPELKEKLEESEKLIKELTVTWEEK--LRKTEEIAQE-------RQRQLESMGISLE 436
Query: 464 LA--KAGD 469
++ K GD
Sbjct: 437 MSGIKVGD 444
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 235 bits (600), Expect = 2e-61
Identities = 171/506 (33%), Positives = 260/506 (51%), Gaps = 70/506 (13%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLL--------GKDKAFTYDFVFDLDTWQ 60
++V VR RP E+ H P +V + K +T+D VF T Q
Sbjct: 19 IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
Query: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMG---TGFDMATSEEEQ--GIIPR 115
+Y + V +++ GYN T+ AYGQTG GKT+TM + + T EE+ GIIPR
Sbjct: 79 IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
Query: 116 AIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIK 175
+ +F + + G EF V LE+YNEE+ DL + + D R ++
Sbjct: 139 TLHQIFEKLTDN----------GTEFSVKVSLLEIYNEELFDLLNPSSDVSER-----LQ 183
Query: 176 IHEDANG--GIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIF--TI 231
+ +D G+ G+ +H+++E+ Q L++GA RTTA+T MN SSRSH++F TI
Sbjct: 184 MFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTI 243
Query: 232 HLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAK 291
H+ + T E K + VDLAGSE + R+GA +RA+
Sbjct: 244 HMKE--------------------TTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAR 283
Query: 292 EGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSD 351
E +IN LL LG VI+AL +++ HVPYR+SKLTR+LQDSLGG ++T +IA +SP+
Sbjct: 284 EAGNINQSLLTLGRVITALVERTP---HVPYRESKLTRILQDSLGGRTRTSIIATISPAS 340
Query: 352 RDFMETLNTLKYANRARNIKNKVVVNQDKTSQQ-ISALRAEIARLQMELMEYKAGKRVIG 410
+ ETL+TL+YA+RA+NI NK VNQ T + I EI RL+ +L + V
Sbjct: 341 LNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYI 400
Query: 411 EDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDG 470
+ E + + + + +++ L ++ A++E + NRVT+L N L D
Sbjct: 401 SE--ENFRVMSGKLTVQEEQIVELIEKIGAVEEEL----NRVTELFMDNKNELDQCKSD- 453
Query: 471 NEAIGALIQNYIREIEELRTKLLESE 496
+QN +E+E + L E++
Sbjct: 454 -------LQNKTQELETTQKHLQETK 472
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 234 bits (598), Expect = 4e-61
Identities = 153/400 (38%), Positives = 223/400 (55%), Gaps = 43/400 (10%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTW--------- 59
V VAVR+RP +EKIE ++ G+ + D Y+F++D+ W
Sbjct: 359 VTVAVRVRPFTKREKIEKASQVVFMS-GKEITVEHPDTKQVYNFIYDVSFWSFDECHPHY 417
Query: 60 --QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAI 117
Q +Y + L+E FEG+N + AYGQTG+GK+YTM GF EE GIIPR
Sbjct: 418 ASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTM-MGFS-----EEPGIIPRFC 471
Query: 118 AHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIH 177
LF +A R Q Q V+ + + F E+YNE+I DL + R+ +++
Sbjct: 472 EDLFSQVA----RKQTQEVS---YHIEMSFFEVYNEKIHDLL--VCKDENGQRKQPLRVR 522
Query: 178 EDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMR 237
E G Y ++ ++ S ++ L+ G R TA+T MN +SSRSH++FT+ + Q +
Sbjct: 523 EHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTK 582
Query: 238 MCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISIN 297
E V G +T++ + +DLAGSER G+R KEG+SIN
Sbjct: 583 --------TEFVEG-------EEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSIN 627
Query: 298 CGLLALGNVISALGDQS-KKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFME 356
LL LG VISAL +Q+ ++ V +PYR+S LT LL++SLGGNS+T MIA +SP+ + E
Sbjct: 628 KSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEE 687
Query: 357 TLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQ 396
TL+TL+YAN+AR I N VN+D ++ I L+AEIA+L+
Sbjct: 688 TLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLK 727
Score = 35.8 bits (81), Expect = 0.35
Identities = 76/380 (20%), Positives = 160/380 (42%), Gaps = 62/380 (16%)
Query: 712 KRLREMNRDLQKLQAAQK-------EHARLLKNQ-SRYERELKKLQAEVAEMKKAKVALM 763
K +RE+ ++ KL+AAQ+ E RL + + + +L + + ++AEM++ +
Sbjct: 714 KLIRELKAEIAKLKAAQRNSRNIDPERYRLCRQEITSLRMKLHQQERDMAEMQR----VW 769
Query: 764 KQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVSALR 823
K+ E+ ++R+L ETK ++ A + + + L + EM+L + + +
Sbjct: 770 KEKFEQAEKRKLQETKELQK-AGIMFQMDNHLPNLVNLNEDPQLSEMLLYMIKEGTTTVG 828
Query: 824 RLAKPMSERVAGRAGL-----KPPMLDSGAEVSASTTSSEAESGARSVS----SIVRQWN 874
+ KP S +G+ + + G VS EA++ +++R +
Sbjct: 829 KY-KPNSSHDIQLSGVLIADDHCTIKNFGGTVSIIPV-GEAKTYVNGKHILEITVLRHGD 886
Query: 875 RKI----NHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQR 930
R I ++F +HP G RP+ + + F A +++M +
Sbjct: 887 RVILGGDHYFRFNHPVEVQKGKRPSGRDTPISEGPKDFEFAKN-----------ELLMAQ 935
Query: 931 MTIVNLEADM-ERLIKKREELF--------LLQEALRRKRERLQAESPEEEKGLQELAEE 981
+ LEA++ E +K +EE+ + Q+ L ++ +++ E L+E ++
Sbjct: 936 RS--QLEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAELREESQR 993
Query: 982 IEVLAANIDYINDGITDCQATIVQLEE------TKEELDSTDTSVVISSCSLAEARLLLD 1035
++ N N I + + LE+ + E+++ T + S+ AR+L
Sbjct: 994 KKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHSIRHARIL-- 1051
Query: 1036 NFLKASIDKGLQVAQKEAQI 1055
+++ Q KE QI
Sbjct: 1052 ----EALETEKQKIAKEVQI 1067
Score = 35.0 bits (79), Expect = 0.59
Identities = 27/114 (23%), Positives = 57/114 (50%), Gaps = 18/114 (15%)
Query: 711 EKRLREMNRDLQKLQAAQKEHARLLKNQ-SRYERELKKLQAEVAEMKKAKVALMKQMREE 769
E +L+ +Q +Q A++ + L +Q + YE ++K L+AE +REE
Sbjct: 945 EAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKIKALEAE--------------LREE 990
Query: 770 QQRRRLVE---TKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVS 820
QR+++ E K N +I +L+K ++ E +I + + + + ++ ++ S
Sbjct: 991 SQRKKMQEINNQKANHKIEELEKAKQHLEQEIYVNKKRLEMETLATKQALEDHS 1044
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 233 bits (595), Expect = 9e-61
Identities = 162/439 (36%), Positives = 222/439 (50%), Gaps = 73/439 (16%)
Query: 6 DCC--VKVAVRIRPQLSKEKIEGCHICTSVT--------PGEPQVLL------------- 42
D C +KV VR+RP+ +KEK G H V P + +V
Sbjct: 7 DLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIK 66
Query: 43 --GKDKAFTYDFVFDLDTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTG 100
KD F +D VFD + Q +++ ++ GYN TVLAYG TGAGKT+TM
Sbjct: 67 KQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTM--- 123
Query: 101 FDMATSEEEQGIIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFD 160
S +E G++ + HL+ + E K E+ + + +LE+YNE+I DL
Sbjct: 124 ---LGSADEPGVMYLTMLHLYKCMDEIK----EEKICS----TAVSYLEVYNEQIRDLLV 172
Query: 161 STRDPDTRHRRSNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNV 220
++ + + ED G+ G+T S EE++ L G +RT T MN
Sbjct: 173 NS---------GPLAVREDTQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNA 223
Query: 221 QSSRSHAIFTIHLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERL 280
SSRSHA+F I+L Q +N+ V AK +DLAGSER
Sbjct: 224 TSSRSHAVFQIYLRQQDKTAS---INQNVR---------------IAKMSLIDLAGSERA 265
Query: 281 KRTGATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQ 340
+GA G R EG +IN LLALGNVI+AL D +K H+PYR+SKLTRLL+DSLGGN Q
Sbjct: 266 STSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQ 325
Query: 341 TIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISAL-------RAEIA 393
TIMIA VSPS + +T NTLKYANRA++IK+ + N + I+ +AEI
Sbjct: 326 TIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEIL 385
Query: 394 RLQMELMEYKAGKRVIGED 412
L+ +L Y+ K E+
Sbjct: 386 LLKEKLKAYEEQKAFTNEN 404
Score = 41.2 bits (95), Expect = 0.008
Identities = 50/230 (21%), Positives = 98/230 (42%), Gaps = 27/230 (11%)
Query: 623 SDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQT--LKHQYEEK------LILL 674
S+P+EKE+ ++ L C + ++++ E + L+ LK Y+++ ++
Sbjct: 412 SNPQEKEIERFQEI--LNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCS 469
Query: 675 QNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLREMNRDLQKLQAAQKEHARL 734
++K+ +RD L L T Y E++ E+ L++ + + L +KE L
Sbjct: 470 EDKVEKATGKRDHRLAMLKTRRSYLEKRR-------EEELKQFDENTNWLHRVEKEMG-L 521
Query: 735 LKNQSRYERELKK------LQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLK 788
L +ELKK L + ++K +M ++Q+ R E N + L+
Sbjct: 522 LSQNGHIPKELKKDLHCHHLHLQNKDLKAQIRHMMDLACLQEQQHRQTEAVLNALLPTLR 581
Query: 789 KEQ---RRQEFQIRALESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAG 835
K+ + A ES ++ E ++ RK V A + +P + G
Sbjct: 582 KQYCTLKEAGLSNAAFESDFKEIEHLVERKKVVVWADQTAEQPKQNDLPG 631
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 225 bits (573), Expect = 3e-58
Identities = 298/1214 (24%), Positives = 501/1214 (41%), Gaps = 179/1214 (14%)
Query: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD--KAFTYDFVFDLDT 58
MA +G V V VR+RP S+E+ G + V+ D K+F +D VF +
Sbjct: 1 MAEEG--AVAVCVRVRPLNSREESLG-ETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNE 57
Query: 59 WQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIA 118
+ +Y + +I+ +GYN T+ AYGQT +GKTYT M SE+ G+IPRAI
Sbjct: 58 TTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYT------MMGSEDHLGVIPRAIH 111
Query: 119 HLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHE 178
+F I + R EF + ++E+YNE I DL T+ + + I E
Sbjct: 112 DIFQKIKKFPDR---------EFLLRVSYMEIYNETITDLLCGTQ------KMKPLIIRE 156
Query: 179 DANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRM 238
D N +Y +T ++++ E ++ + +G SR T+MN +SSRSH IF + L
Sbjct: 157 DVNRNVYVADLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMIL----- 211
Query: 239 CTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINC 298
G P + E + + VDLAGSER +TGA G R KEG +IN
Sbjct: 212 -----------ESREKGEPSNCEGSVKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINR 260
Query: 299 GLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETL 358
L LG VI L D + + YRDSKLTR+LQ+SLGGN++T +I ++P F ETL
Sbjct: 261 SLFILGQVIKKLSD-GQVGGFINYRDSKLTRILQNSLGGNAKTRIICTITPV--SFDETL 317
Query: 359 NTLKYANRARNIKNKVVVNQDKTSQQ-ISALRAEIARLQMELMEYKAGKRVIGEDGAEGY 417
L++A+ A+ +KN VN+ T + + R EI L+ +L E R + +
Sbjct: 318 TALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEEVSLETRAQAME-KDQL 376
Query: 418 SDLFRENAMLQK------ENGALRL----RVKAMQEAIDAINNRVTQLMSQEANLLLAKA 467
+ L E +LQK EN L + QE RVT + + + +
Sbjct: 377 AQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRRVTWCLGKINKMKNSNY 436
Query: 468 GDG-------NEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGAS 520
D L N +REI+E + ES+ + +L +LS L
Sbjct: 437 ADQFNIPTNITTKTHKLSINLLREIDE--SVCSESDVFSNTL-DTLSEIEWNPATKLLNQ 493
Query: 521 PAAPAFGGSPASSMEDA---SEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQE 577
+ S + ++ E +R K+++E LK KE + E EA +++ K QE
Sbjct: 494 ENIESELNSLRADYDNLVLDYEQLRTEKEEME-LKLKE---KNDLDEFEALERKTKKDQE 549
Query: 578 --------NSEETDENEAEEEEEERDESGCEEEEGREDEDE--------DSGSEESL--- 618
N + ++ ++ +E + E RE ED+ DS E++
Sbjct: 550 MQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMD 609
Query: 619 ----VDSDSDPEE-KEVNFQADLADLTCE----------IEIKQKLIDELENSQRRLQTL 663
++S DP++ K+ F A+ L + +E+K+K+ EL + ++++
Sbjct: 610 LSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKM-KELATTYKQMEND 668
Query: 664 KHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANK---IKADYEKRLREMNRD 720
Y+ +L + D + E ++ + + K K + E ++ ++ ++
Sbjct: 669 IQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKE 728
Query: 721 LQK---LQAAQKEHARLLKNQSRYERELKKLQAEVAEM------------KKAKVALMKQ 765
L K A +E LL E+++L+ E+ + K + K+
Sbjct: 729 LNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKE 788
Query: 766 MREEQQRRRLVETKRNREIAQLKKEQRRQEFQ-IRALESQKRQQ-EMVLRRKTQEVSALR 823
R + + +TK + Q + QEFQ + L Q+ +MVL + +
Sbjct: 789 SRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIV 848
Query: 824 RLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHFLGD 883
L+K + + LK + E+ T E + + + Q + +
Sbjct: 849 NLSKEAQKFDSSLGALKTELSYKTQELQEKT--REVQERLNEMEQLKEQLENRDSTLQTV 906
Query: 884 HPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEAD-MER 942
T+ + + + K +Q +L+ +SL+ + VN+ D E+
Sbjct: 907 EREKTLITEKLQQTLEEVKTLTQEKDDLKQLQ-ESLQIERDQLKSDIHDTVNMNIDTQEQ 965
Query: 943 LIKKREELFLLQEALRRKRERLQAESPEE---EKGLQELAEEIEVLAANIDYIND----- 994
L E L QE + + ++ E E+ E +E + ID D
Sbjct: 966 LRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKN 1025
Query: 995 -----------GITDCQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASID 1043
I + Q I L + K EL SV+ AE L + LK +I+
Sbjct: 1026 TQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVI------AEKEQLKTD-LKENIE 1078
Query: 1044 KGLQVAQKEAQIRLLEGRL-RQTDMAGSSQNHLLL----------------DALREKAEA 1086
+ + ++RLL L +Q ++ +NH + + L+EK++
Sbjct: 1079 ---MTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQ 1135
Query: 1087 HPELQALIYNVQQE 1100
E Q + NVQ+E
Sbjct: 1136 LQEKQQQLLNVQEE 1149
Score = 65.9 bits (159), Expect = 3e-10
Identities = 129/723 (17%), Positives = 297/723 (41%), Gaps = 104/723 (14%)
Query: 374 VVVNQDKTSQQISALRAEIARLQMEL-------MEYKAGKRVIGEDGAEGYSDLFRENAM 426
++ +++ Q + ++ AE +L+ +L +E + R++G++ + + +E
Sbjct: 1048 LIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNH 1107
Query: 427 LQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIE 486
K+ G L + E + + + QL ++ LL + +Q I EIE
Sbjct: 1108 AIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSE------MQKKINEIE 1161
Query: 487 ELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQ 546
L+ +L E E + + E+ ++ +
Sbjct: 1162 NLKNELKNKELTLEHMET-------------------------------ERLELAQKLNE 1190
Query: 547 DLERLK-----KKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEE 601
+ E +K +K +++ +KS E E R +++ + +EE + +E
Sbjct: 1191 NYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQT----KEELKIAHIHLKE 1246
Query: 602 EEGREDEDEDSGSEESL-VDSDSDPEEKEVNFQADLADLTCEIEI---------KQKLID 651
+ DE S SE++ + + D E+ Q ++ L E E+ Q+ ++
Sbjct: 1247 HQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMN 1306
Query: 652 ELE-----------NSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTE 700
ELE + R++ + + EK Q +I+ ERD NL T++ E
Sbjct: 1307 ELELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERD----NLKTIKEALE 1362
Query: 701 EKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKV 760
K +++K + +RE +Q+ Q+ Q++ N + E K+ +E+ + K
Sbjct: 1363 VKHDQLK----EHIRETLAKIQESQSKQEQSL----NMKEKDNETTKIVSEMEQFKPKDS 1414
Query: 761 ALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQEVS 820
AL++ E L +KR +E K +++ ++ L+ + + L+ +E+
Sbjct: 1415 ALLRIEIE-----MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIV 1469
Query: 821 ALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKINHF 880
A + L +VA + + V+ S +E + + + +I + KI
Sbjct: 1470 A-KHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEI 1528
Query: 881 LGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADM 940
+ ++K + + KA QS+E +++++ + + + ++
Sbjct: 1529 YEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLELTNR---LQESQEEI 1585
Query: 941 ERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQ 1000
+ +IK++EE+ +QEAL+ +R++L+ + E ++E ++E E + +N + Q
Sbjct: 1586 QIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKE-SQEKEYQFLKMTAVN----ETQ 1640
Query: 1001 ATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLLEG 1060
+ ++E KE+ ++ ++ ++ + L L ++++ V ++ +R +E
Sbjct: 1641 EKMCEIEHLKEQFETQKLNLE----NIETENIRLTQILHENLEEMRSVTKERDDLRSVEE 1696
Query: 1061 RLR 1063
L+
Sbjct: 1697 TLK 1699
Score = 62.8 bits (151), Expect = 3e-09
Identities = 142/700 (20%), Positives = 283/700 (40%), Gaps = 123/700 (17%)
Query: 369 NIKNKVVVNQDKTSQQISAL-RAEIARLQMELMEYKAGKRVIGEDGAEGYSDLFRENAML 427
N K+V ++ + SAL R EI L + ++ + + A+ DL R +L
Sbjct: 1397 NETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEM--KSVAKEKDDLQRLQEVL 1454
Query: 428 QKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKA--GDGNEAIGALIQNYIREI 485
Q E+ L+ +K + V + + E L +A + E I L N +
Sbjct: 1455 QSESDQLKENIKEI----------VAKHLETEEELKVAHCCLKEQEETINELRVNLSEKE 1504
Query: 486 EELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAK 545
E+ T + EA+N+ L+ + + + + E + K
Sbjct: 1505 TEISTIQKQLEAINDKLQNKIQEIYEKEEQF-------------NIKQISEVQEKVNELK 1551
Query: 546 QDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEGR 605
Q E K K+ +S E + + +LQ E+ EE E+EE +R + + E
Sbjct: 1552 QFKEHRKAKD--SALQSIESKMLELTNRLQ-ESQEEIQIMIKEKEEMKRVQEALQIER-- 1606
Query: 606 EDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKH 665
D+ + + +V + +EKE F +K ++E + ++ LK
Sbjct: 1607 ---DQLKENTKEIVAKMKESQEKEYQF------------LKMTAVNETQEKMCEIEHLKE 1651
Query: 666 QYEEKLILLQNKIRDTQLERDRVL-QNLSTMECYTEEKANKIKADYEKRLREMNRDLQKL 724
Q+E + + L+N I + ++L +NL M T+E+ + LR + L+
Sbjct: 1652 QFETQKLNLEN-IETENIRLTQILHENLEEMRSVTKERDD---------LRSVEETLKVE 1701
Query: 725 QAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREI 784
+ KE+ R R+L+K + E+K + L + + R +V K N EI
Sbjct: 1702 RDQLKENLR-----ETITRDLEKQE----ELKIVHMHLKEHQETIDKLRGIVSEKTN-EI 1751
Query: 785 AQLKKEQRRQEFQIRA----LESQKRQQEMVLRRKTQEVSALRRLAKPMSERVAGRAGLK 840
+ ++K+ ++A ++ + R M L+ + + + LR + +SE+ + ++
Sbjct: 1752 SNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGI---VSEKTDKLSNMQ 1808
Query: 841 PPMLDSGAEVSASTTSSEA-ESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKF 899
+ +S A++ +A E ++ V + +K++ + K
Sbjct: 1809 KDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEM--------------EQLKK 1854
Query: 900 QKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRR 959
Q K S + SK I ++ + + NLE +M+ ++K+R+ L RR
Sbjct: 1855 QIKDQSLTLSKL----------EIENLNLAQKLHENLE-EMKSVMKERDNL-------RR 1896
Query: 960 KRERLQAESPEEEKGLQEL-AEEIEVLAANIDYINDGITDCQATIVQLEETKEELDSTDT 1018
E L+ E + ++ LQE A ++E+ + + + +E KE +D
Sbjct: 1897 VEETLKLERDQLKESLQETKARDLEIQ-----------QELKTARMLSKEHKETVDKLRE 1945
Query: 1019 SVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLL 1058
+ + +++ + LD K + K +Q QK+ +++LL
Sbjct: 1946 KISEKTIQISDIQKDLDK-SKDELQKKIQELQKK-ELQLL 1983
Score = 57.4 bits (137), Expect = 1e-07
Identities = 157/836 (18%), Positives = 334/836 (39%), Gaps = 132/836 (15%)
Query: 362 KYANRARNIKNKVVVNQDKTSQQISALRAEIA-RLQMELMEYKA---GKRVIGE------ 411
K N N+KN++ N++ T + + R E+A +L E K+ ++V+ E
Sbjct: 1155 KKINEIENLKNELK-NKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFE 1213
Query: 412 ---DGAEGYSDLFRENAMLQKENGAL-RLRVKAMQEAIDAINNRVTQLMSQEANLL-LAK 466
D GY + KE + + +K QE ID + V++ +Q N L K
Sbjct: 1214 TERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEK 1273
Query: 467 AGDG-NEAIGALIQNY-----IREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGAS 520
+ E I L + ++E+ E + + E E + E
Sbjct: 1274 SHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQ------------------- 1314
Query: 521 PAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSPEKEAFKKRAKLQQENSE 580
S+ +D++ + A+ ++ERL+ E Q + K K+R L+ +
Sbjct: 1315 -----------STTKDSTTL---ARIEMERLRLNEKFQESQEEIKSLTKERDNLK--TIK 1358
Query: 581 ETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLT 640
E E + ++ +E E+ + +E + +++ +E ++ E E D A L
Sbjct: 1359 EALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLR 1418
Query: 641 CEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTE 700
EIE+ L L+ S ++++ + ++ LQ Q E D++ +N+ +
Sbjct: 1419 IEIEMLG-LSKRLQESHDEMKSVAKEKDD----LQRLQEVLQSESDQLKENIKEIVAKHL 1473
Query: 701 EKANKIKADYEKRLREMNRDLQKLQAAQKEHARLLKN-QSRYERELKKLQAEVAEM-KKA 758
E ++K + L+E + +L+ E + Q + E KLQ ++ E+ +K
Sbjct: 1474 ETEEELKVAH-CCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKE 1532
Query: 759 KVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMVLRRKTQE 818
+ +KQ+ E Q++ E+ Q K+ ++ ++ ++++ES+ + L+ +E
Sbjct: 1533 EQFNIKQISEVQEKVN--------ELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEE 1584
Query: 819 VSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSSEAESGARSVSSIVRQWNRKIN 878
+ + + + M + + + + + + + +++ K
Sbjct: 1585 IQIMIKEKEEMKR----------------VQEALQIERDQLKENTKEIVAKMKESQEKEY 1628
Query: 879 HFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEA 938
FL VN T+ K + + + F + +L +++E +I + ++ NLE
Sbjct: 1629 QFL---KMTAVNETQ--EKMCEIEHLKEQF-ETQKLNLENIETE--NIRLTQILHENLE- 1679
Query: 939 DMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITD 998
+M + K+R++L ++E L+ +R++L+ E E EE++++ ++ + I
Sbjct: 1680 EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDK 1739
Query: 999 CQATIVQLEETKEELDSTDTSVVISSCSLAEARLLLDNFLKASIDKGLQVAQKEAQIRLL 1058
+ + E E+ + + S+ +L L + L+ + + + +++ I L
Sbjct: 1740 LRGIV---SEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIA---HMHLKEQQETIDKL 1793
Query: 1059 EGRL-RQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEEISEFSEGS 1117
G + +TD + Q L EN A E+I E + +
Sbjct: 1794 RGIVSEKTDKLSNMQKDL------------------------ENSNAKLQEKIQEL-KAN 1828
Query: 1118 FSQSFTMKGSTSHDDFKFKSEPKLSAQMKAVSAECLGPPLDISTKNITKSLASLVE 1173
Q T+K + K +L Q+K S L+I N+ + L +E
Sbjct: 1829 EHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL--SKLEIENLNLAQKLHENLE 1882
Score = 36.6 bits (83), Expect = 0.20
Identities = 63/333 (18%), Positives = 126/333 (37%), Gaps = 54/333 (16%)
Query: 547 DLERLKKKEVRQRRKSPEKEAF--KKRAKLQQENSEETDENEAEEEEEERDESGCEEEEG 604
D+E+LK ++ + + F + + E++E + + +E E+D +E+
Sbjct: 2281 DIEKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNE 2340
Query: 605 REDEDEDSGSEESLVDSDSDP---EEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQ 661
+ ++ + + +P + K + + LT E I ELENS +
Sbjct: 2341 KLFKNYQTLKTSLASGAQVNPTTQDNKNPHVTSRATQLTTE------KIRELENSLHEAK 2394
Query: 662 TLKHQYEEKLILLQNKIRDTQ----------LERDRVLQNLSTMECYTEEKANKIKADYE 711
E K+I +Q ++ T E ++ L+ ++K Y+
Sbjct: 2395 ESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYK 2454
Query: 712 KRLREMNRDLQKLQAAQKEHARLLKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQ 771
+ + ++ L K+ + +KN +E+E+ +A V K+ L + +R QQ
Sbjct: 2455 EEIEDLKMKLVKIDLEK------MKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQ 2508
Query: 772 RRRLVETK---------------------RNREIAQLKKEQRRQEFQIRALESQKRQQEM 810
+ +N + LK E R E +I L K+Q E
Sbjct: 2509 AQDTSVISEHTDPQPSNKPLTCGGGSGIVQNTKALILKSEHIRLEKEISKL---KQQNEQ 2565
Query: 811 VLRRKTQEVSALRRLA---KPMSERVAGRAGLK 840
++++K + +S + L+ K ER R K
Sbjct: 2566 LIKQKNELLSNNQHLSNEVKTWKERTLKREAHK 2598
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 221 bits (563), Expect = 4e-57
Identities = 169/494 (34%), Positives = 239/494 (48%), Gaps = 80/494 (16%)
Query: 11 VAVRIRPQLSKEKIEGCHICTSVTPGEPQVLL--------------GKDKAFTYDFVFDL 56
VA+R+RP E EG + + VL+ ++K++ +D FD
Sbjct: 14 VALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAFDF 73
Query: 57 DTWQEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRA 116
QE +Y LIEG GYNATV AYG TG GKTYTM +++E GI +
Sbjct: 74 TATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTM------LGTDQEPGIYVQT 127
Query: 117 IAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKI 176
+ LF RA E+ E++VS +LE+YNE I DL + + +++
Sbjct: 128 LNDLF--------RAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSL--------GYLEL 171
Query: 177 HEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQM 236
ED+ G I G+T + +E++Q L +G RT T N SSRSHA+ + + Q
Sbjct: 172 REDSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQR 231
Query: 237 RMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISI 296
+++ E G + +DLAGSER +T G+R KEG I
Sbjct: 232 SRVK--NILQEVRQG----------------RLFMIDLAGSERASQTQNRGQRMKEGAHI 273
Query: 297 NCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFME 356
N LLALGN I+AL D+ ++ YRDSKLTRLL+DSLGGNS+T+MIA +SP+ F E
Sbjct: 274 NRSLLALGNCINALSDKGSNK-YINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEE 332
Query: 357 TLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGED---- 412
+ NTL YA RA+NIK +V N S I+ + IA L+ E+ KR I E
Sbjct: 333 SRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQYTSIIADLRGEIQRL---KRKIDEQTGRG 389
Query: 413 ---GAEGYSDLFRENAMLQKEN--------GALRLRV-KAMQEAIDA------INNRVTQ 454
G + D+ A +Q + G LR ++ A QE +D + NR +
Sbjct: 390 QARGRQDRGDIRHIQAEVQLHSGQGEKAGMGQLREQLASAFQEQMDVRRRLLELENRAME 449
Query: 455 LMSQEANLLLAKAG 468
+ + LL AG
Sbjct: 450 VQIDTSRHLLTIAG 463
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 220 bits (561), Expect = 8e-57
Identities = 206/780 (26%), Positives = 343/780 (43%), Gaps = 116/780 (14%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD-KAFTYDFVFDLDTW-------- 59
VKVAVR+RP S+E + + ++ K+ K F FD W
Sbjct: 6 VKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPEDP 65
Query: 60 ----QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQ-GIIP 114
Q ++Y+ +++ FEGYN + AYGQTGAGK+YTM M EE Q GIIP
Sbjct: 66 CFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTM-----MGKQEESQAGIIP 120
Query: 115 RAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNI 174
+ LF I + + V ++E+Y E + DL + + N+
Sbjct: 121 QLCEELFEKINDNCNEEMS-------YSVEVSYMEIYCERVRDLLNPKN-------KGNL 166
Query: 175 KIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLC 234
++ E G Y ++ + S ++ + G +RT A+T MN SSRSHA+FTI
Sbjct: 167 RVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFT 226
Query: 235 QMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGI 294
Q + + +L E V+ K VDLAGSER TGA G R KEG
Sbjct: 227 QKKHDNETNLSTEKVS-----------------KISLVDLAGSERADSTGAKGTRLKEGA 269
Query: 295 SINCGLLALGNVISALGDQSKK---VVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSD 351
+IN L LG VISAL + SKK +PYRDS LT LL+++LGGNS+T M+A +SP+D
Sbjct: 270 NINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPAD 329
Query: 352 RDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEYKAGKRVIGE 411
++ ETL+TL+YA+RA+ IK V+N+D ++ + L+ E+ RL+ L G +
Sbjct: 330 INYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDII--- 386
Query: 412 DGAEGYSDLFRENAMLQKENGALRL------------------RVKAMQEAIDAINN--- 450
D + G + L + G + R+K ++ I +N
Sbjct: 387 DTSMGSLTSSPSSCSLSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWE 446
Query: 451 ---RVTQLMSQEANLLLAKAG----DGNEAIGALIQNYIREIEELRTKLLESEAMNESLR 503
R T+ + E LLA+ G + +G + L L SE + ++
Sbjct: 447 EKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIK 506
Query: 504 RSLSR-----ASARSPYSLGASPAAP---AFGGSPASSME--------DASEVI---RRA 544
++R A R L + F ++S E + SE +R
Sbjct: 507 DGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRV 566
Query: 545 KQDLER-------LKKKEVRQRRKSPEKEAFKKRAKLQQENSEETDENEAEEEEEERDES 597
Q ++ + K V + + A +++ + SE D A+ E E+
Sbjct: 567 SQPVQLRSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGI 626
Query: 598 GCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLID--ELEN 655
++E + ++ + ++ ++D E++ +++++ L L ++E + + E E
Sbjct: 627 DMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEE 686
Query: 656 SQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLSTMECYTEEKANKIKADYEKRLR 715
+ + +H++E L Q R + + L++L ++AN I + +K+++
Sbjct: 687 EEEEVPWTQHEFE----LAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQ 742
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 220 bits (560), Expect = 1e-56
Identities = 145/405 (35%), Positives = 209/405 (51%), Gaps = 53/405 (13%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD-KAFTYDFVFDLDTW-------- 59
VKVAVR+RP S+E + + ++ K+ K F FD W
Sbjct: 6 VKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPEDP 65
Query: 60 ----QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQ-GIIP 114
Q ++Y+ +++ FEGYN + AYGQTGAGK+YTM M EE Q GIIP
Sbjct: 66 CFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTM-----MGKQEESQAGIIP 120
Query: 115 RAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNI 174
+ LF I + + V ++E+Y E + DL + + N+
Sbjct: 121 QLCEELFEKINDNCNEEMS-------YSVEVSYMEIYCERVRDLLNPKN-------KGNL 166
Query: 175 KIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLC 234
++ E G Y ++ + S ++ + G +RT A+T MN SSRSHA+FTI
Sbjct: 167 RVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFT 226
Query: 235 QMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGI 294
Q + + +L E V+ K VDLAGSER TGA G R KEG
Sbjct: 227 QKKHDNETNLSTEKVS-----------------KISLVDLAGSERADSTGAKGTRLKEGA 269
Query: 295 SINCGLLALGNVISALGDQSKK---VVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSD 351
+IN L LG VISAL + SKK +PYRDS LT LL+++LGGNS+T M+A +SP+D
Sbjct: 270 NINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPAD 329
Query: 352 RDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQ 396
++ ETL+TL+YA+RA+ IK V+N+D ++ + L+ E+ RL+
Sbjct: 330 INYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLK 374
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 219 bits (559), Expect = 1e-56
Identities = 170/524 (32%), Positives = 259/524 (49%), Gaps = 98/524 (18%)
Query: 9 VKVAVRIRPQLSKE--KIEGCHI------CTSVTPGEPQVLLGKDKAFTYDFVFDLDTW- 59
VKVAVR+RP S+E + C I T V P +P+ K+F++D+ + T
Sbjct: 6 VKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKET---PKSFSFDYSYWSHTSP 62
Query: 60 -------QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSE-EEQG 111
Q+Q+Y ++++ FEGYN + AYGQTGAGK+YTM M E ++QG
Sbjct: 63 EDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTM-----MGKQEKDQQG 117
Query: 112 IIPRAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRR 171
IIP+ LF I + + V ++E+Y E + DL + +
Sbjct: 118 IIPQLCEDLFSRINDTTNDNMS-------YSVEVSYMEIYCERVRDLLNPKN-------K 163
Query: 172 SNIKIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTI 231
N+++ E G Y ++ + S ++ + G +RT A+T MN SSRSHA+F I
Sbjct: 164 GNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNI 223
Query: 232 HLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAK 291
Q R + ++ E V+ K VDLAGSER TGA G R K
Sbjct: 224 IFTQKRHDAETNITTEKVS-----------------KISLVDLAGSERADSTGAKGTRLK 266
Query: 292 EGISINCGLLALGNVISALGD---------QSKKVVHVPYRDSKLTRLLQDSLGGNSQTI 342
EG +IN L LG VISAL + + KK +PYRDS LT LL+++LGGNS+T
Sbjct: 267 EGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTA 326
Query: 343 MIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELMEY 402
M+A +SP+D ++ ETL+TL+YA+RA+ I+ V+N+D ++ I L+ E+ RL+ L
Sbjct: 327 MVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLY-- 384
Query: 403 KAGKRVIGEDGAEGYSDLF-RENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEAN 461
A+G D+ NA++ + ++ A+++R + S
Sbjct: 385 -----------AQGLGDITDMTNALVG----------MSPSSSLSALSSRAASVSSLHER 423
Query: 462 LLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRS 505
+L A + EAI L +E E++ +L +E E LRR+
Sbjct: 424 ILFAPGSE--EAIERL-----KETEKIIAEL--NETWEEKLRRT 458
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 218 bits (556), Expect = 3e-56
Identities = 145/409 (35%), Positives = 218/409 (53%), Gaps = 53/409 (12%)
Query: 9 VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKD-----KAFTYDFVFDLDTW---- 59
VKVAVR+RP ++E + S+ ++ K K+FT+D+ + T
Sbjct: 6 VKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTEDP 65
Query: 60 ----QEQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEE-EQGIIP 114
Q+Q+Y +++ FEGYN + AYGQTGAGK+YTM M E +QGI+P
Sbjct: 66 QFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTM-----MGRQEPGQQGIVP 120
Query: 115 RAIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNI 174
+ LF ++E + A + V ++E+Y E + DL + R ++
Sbjct: 121 QLCEDLFSRVSENQS-------AQLSYSVEVSYMEIYCERVRDLLNPKS-------RGSL 166
Query: 175 KIHEDANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLC 234
++ E G Y ++ + S ++ + G +RT A+T MN SSRSHA+FTI
Sbjct: 167 RVREHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFT 226
Query: 235 QMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGI 294
Q ++ +TGL +K VDLAGSER +GA G R KEG
Sbjct: 227 QR--------CHDQLTGLDSEK---------VSKISLVDLAGSERADSSGARGMRLKEGA 269
Query: 295 SINCGLLALGNVISALGD---QSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSD 351
+IN L LG VISAL D + +K +PYRDS LT LL+++LGGNS+T MIA +SP+D
Sbjct: 270 NINKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPAD 329
Query: 352 RDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQMELM 400
++ ETL+TL+YA+R + I+ ++N+D ++ I L+ E+ARL+ LM
Sbjct: 330 INYEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLM 378
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,817,398
Number of Sequences: 37866
Number of extensions: 2757759
Number of successful extensions: 50984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 958
Number of HSP's successfully gapped in prelim test: 1488
Number of HSP's that attempted gapping in prelim test: 15306
Number of HSP's gapped (non-prelim): 15283
length of query: 1624
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1508
effective length of database: 13,855,062
effective search space: 20893433496
effective search space used: 20893433496
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.