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Search of human proteins with 83700235
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
(407 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s... 809 0.0
gi|4503529 eukaryotic translation initiation factor 4A isoform 1... 736 0.0
gi|7661920 eukaryotic translation initiation factor 4A, isoform ... 545 e-155
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 273 2e-73
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H... 272 5e-73
gi|8922886 DDX19-like protein [Homo sapiens] 270 2e-72
gi|4758112 HLA-B associated transcript 1 [Homo sapiens] 260 2e-69
gi|18375623 HLA-B associated transcript 1 [Homo sapiens] 260 2e-69
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi... 259 3e-69
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap... 256 3e-68
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [... 252 5e-67
gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [... 244 8e-65
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi... 244 8e-65
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 209 3e-54
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 207 1e-53
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 202 4e-52
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 202 6e-52
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 202 6e-52
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 201 8e-52
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 199 4e-51
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 196 2e-50
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 196 4e-50
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 195 7e-50
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 192 4e-49
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 192 4e-49
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 192 4e-49
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 191 8e-49
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 191 8e-49
gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo sapi... 181 8e-46
gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo sapi... 181 8e-46
>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
sapiens]
Length = 407
Score = 809 bits (2089), Expect = 0.0
Identities = 407/407 (100%), Positives = 407/407 (100%)
Query: 1 MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQ 60
MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQ
Sbjct: 1 MSGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQ 60
Query: 61 QRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKV 120
QRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKV
Sbjct: 61 QRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKV 120
Query: 121 ILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMF 180
ILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMF
Sbjct: 121 ILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMF 180
Query: 181 VLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 240
VLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE
Sbjct: 181 VLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 240
Query: 241 ELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTV 300
ELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTV
Sbjct: 241 ELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTV 300
Query: 301 SALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHR 360
SALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHR
Sbjct: 301 SALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHR 360
Query: 361 IGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
IGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI
Sbjct: 361 IGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
[Homo sapiens]
Length = 406
Score = 736 bits (1901), Expect = 0.0
Identities = 364/403 (90%), Positives = 388/403 (96%)
Query: 5 SADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAI 64
S D GP+GM+P+GVIESNWNEIVD+FDDMNL ESLLRGIYAYGFEKPSAIQQRAI
Sbjct: 4 SQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAI 63
Query: 65 IPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILAL 124
+PCIKGYDVIAQAQSGTGKTATFAISILQQ+E++ K TQALVLAPTRELAQQIQKV++AL
Sbjct: 64 LPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMAL 123
Query: 125 GDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDE 184
GDYMGA+CHACIGGTNVR E+QKLQ EAPHI+VGTPGRVFDMLNRRYLSPK+IKMFVLDE
Sbjct: 124 GDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDE 183
Query: 185 ADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTL 244
ADEMLSRGFKDQIY+IFQKLN++ QVVLLSATMP+DVLEVTKKFMRDPIRILVKKEELTL
Sbjct: 184 ADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTL 243
Query: 245 EGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALH 304
EGI+QFYINVEREEWKLDTLCDLYETLTITQAVIF+NTRRKVDWLTEKMHARDFTVSA+H
Sbjct: 244 EGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMH 303
Query: 305 GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 364
GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG
Sbjct: 304 GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 363
Query: 365 GRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407
GRFGRKGVAIN VTEEDKR LRDIETFYNT++EEMP+NVADLI
Sbjct: 364 GRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
[Homo sapiens]
Length = 411
Score = 545 bits (1404), Expect = e-155
Identities = 270/378 (71%), Positives = 322/378 (85%), Gaps = 1/378 (0%)
Query: 30 EIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAI 89
++ FD M L+E LLRGIYAYGFEKPSAIQQRAI IKG DVIAQ+QSGTGKTATF+I
Sbjct: 35 DVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSI 94
Query: 90 SILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 149
S+LQ L+I+ +ETQAL+LAPTRELA QIQK +LALGDYM CHACIGGTNV +++KL
Sbjct: 95 SVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD 154
Query: 150 AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 209
H+V GTPGRVFDM+ RR L + IKM VLDEADEML++GFK+QIY++++ L + Q
Sbjct: 155 Y-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213
Query: 210 VVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYE 269
VVL+SAT+P ++LE+T KFM DPIRILVK++ELTLEGIKQF++ VEREEWK DTLCDLY+
Sbjct: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYD 273
Query: 270 TLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLIT 329
TLTITQAVIF NT+RKVDWLTEKM +FTVS++HGDM QKER+ IM+EFRSG+SRVLI+
Sbjct: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333
Query: 330 TDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIE 389
TD+ ARG+DV QVSL+INYDLP NRE YIHRIGR GR+GRKGVAINFV +D RILRDIE
Sbjct: 334 TDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIE 393
Query: 390 TFYNTTVEEMPMNVADLI 407
+Y+T ++EMPMNVADLI
Sbjct: 394 QYYSTQIDEMPMNVADLI 411
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 273 bits (698), Expect = 2e-73
Identities = 143/372 (38%), Positives = 233/372 (62%), Gaps = 4/372 (1%)
Query: 33 DNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISIL 92
+ F+D LK LL GI+ G+EKPS IQ+ +I + G D++A+A++GTGK+ + I +L
Sbjct: 96 NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 155
Query: 93 QQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMG-ATCHACIGGTNVRNEMQKLQAE 151
++L+++ QA+V+ PTRELA Q+ ++ + + +MG A A GGTN+R+++ +L +
Sbjct: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 214
Query: 152 APHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV 211
H+V+ TPGR+ D++ + ++M VLDEAD++LS+ F + +I L + Q++
Sbjct: 215 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 274
Query: 212 LLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
L SAT P V + ++ P I + EELTL+G+ Q+Y V E K+ L L+ L
Sbjct: 275 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLNTLFSRL 332
Query: 272 TITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTD 331
I Q++IF N+ ++V+ L +K+ ++ +H M Q+ R+ + +FR+G R L+ TD
Sbjct: 333 QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392
Query: 332 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETF 391
L RGID+Q V++VIN+D P E Y+HRIGR GRFG G+AIN +T +D+ L+ IE
Sbjct: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452
Query: 392 YNTTVEEMPMNV 403
T ++ +P N+
Sbjct: 453 LGTEIKPIPSNI 464
>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
sapiens]
Length = 479
Score = 272 bits (695), Expect = 5e-73
Identities = 157/389 (40%), Positives = 241/389 (61%), Gaps = 18/389 (4%)
Query: 32 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKG--YDVIAQAQSGTGKTATFAI 89
V +F+++ LK LL+G+YA GF +PS IQ+ A+ + ++IAQ+QSGTGKTA F +
Sbjct: 91 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 150
Query: 90 SILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGAT--CHACIGGTNVRNEMQK 147
++L Q+E K Q L L+PT ELA Q KVI +G + +A G N++++
Sbjct: 151 AMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-----NKLER 205
Query: 148 LQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEMLS-RGFKDQIYEIFQKLN 205
Q + IV+GTPG V D ++ +++ PK IK+FVLDEAD M++ +G +DQ I + L
Sbjct: 206 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 265
Query: 206 TSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLC 265
+ Q++L SAT V + +K + DP I +K+EE TL+ IKQ+Y+ + K LC
Sbjct: 266 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 325
Query: 266 DLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSR 325
+LY +TI QA+IF +TR+ WL ++ V+ L G+M ++R ++ FR G +
Sbjct: 326 NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 385
Query: 326 VLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINFV-T 378
VL+TT++ ARGIDV+QVS+VIN+DLP ++ E Y+HRIGR GRFG++G+A+N V +
Sbjct: 386 VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 445
Query: 379 EEDKRILRDIETFYNTTVEEMPMNVADLI 407
+ IL I+ +N +E + + D I
Sbjct: 446 KHSMNILNRIQEHFNKKIERLDTDDLDEI 474
>gi|8922886 DDX19-like protein [Homo sapiens]
Length = 478
Score = 270 bits (690), Expect = 2e-72
Identities = 155/389 (39%), Positives = 241/389 (61%), Gaps = 18/389 (4%)
Query: 32 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKG--YDVIAQAQSGTGKTATFAI 89
V +F+++ LK LL+G+YA GF +PS IQ+ A+ + ++IAQ+QSGTGKTA F +
Sbjct: 90 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPMMLAEPPQNLIAQSQSGTGKTAAFVL 149
Query: 90 SILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGAT--CHACIGGTNVRNEMQK 147
++L ++E + Q L L+PT ELA Q KVI +G + +A G N++++
Sbjct: 150 AMLSRVEPSDRYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRG-----NKLER 204
Query: 148 LQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEMLS-RGFKDQIYEIFQKLN 205
Q + IV+GTPG V D ++ +++ PK IK+FVLDEAD M++ +G +DQ I + L
Sbjct: 205 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 264
Query: 206 TSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLC 265
+ Q++L SAT V + +K + DP I +K+EE TL+ IKQ+Y+ + K LC
Sbjct: 265 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 324
Query: 266 DLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSR 325
+LY +TI QA+IF +TR+ WL ++ V+ L G+M ++R ++ FR G +
Sbjct: 325 NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 384
Query: 326 VLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINFV-T 378
VL+TT++ ARGIDV+QVS+VIN+DLP ++ E Y+HRIGR GRFG++G+A+N V +
Sbjct: 385 VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 444
Query: 379 EEDKRILRDIETFYNTTVEEMPMNVADLI 407
+ IL I+ +N +E + + D I
Sbjct: 445 KHSMNILNRIQEHFNKKIERLDTDDLDEI 473
>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 260 bits (664), Expect = 2e-69
Identities = 144/370 (38%), Positives = 219/370 (59%), Gaps = 5/370 (1%)
Query: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
F D LK LLR I GFE PS +Q I I G DV+ QA+SG GKTA F ++ LQQ
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 95 LEIEFKETQALVLAPTRELAQQIQKVILALGDYM-GATCHACIGGTNVRNEMQKLQAEAP 153
LE + LV+ TRELA QI K YM GG +++ + + L+ P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166
Query: 154 HIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR-GFKDQIYEIFQKLNTSIQVVL 212
HIVVGTPGR+ + + L+ K IK F+LDE D+ML + + + EIF+ QV++
Sbjct: 167 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 226
Query: 213 LSATMPTDVLEVTKKFMRDPIRILVKKE-ELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
SAT+ ++ V +KFM+DP+ I V E +LTL G++Q+Y+ ++ E K L DL + L
Sbjct: 227 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 285
Query: 272 TITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTD 331
Q VIF+ + ++ L + + ++F A+H M Q+ER ++F+ R+L+ T+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345
Query: 332 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEE-DKRILRDIET 390
L RG+D+++V++ NYD+P + + Y+HR+ R GRFG KG+AI FV++E D +IL D++
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405
Query: 391 FYNTTVEEMP 400
+ + E+P
Sbjct: 406 RFEVNISELP 415
>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
Length = 428
Score = 260 bits (664), Expect = 2e-69
Identities = 144/370 (38%), Positives = 219/370 (59%), Gaps = 5/370 (1%)
Query: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
F D LK LLR I GFE PS +Q I I G DV+ QA+SG GKTA F ++ LQQ
Sbjct: 47 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106
Query: 95 LEIEFKETQALVLAPTRELAQQIQKVILALGDYM-GATCHACIGGTNVRNEMQKLQAEAP 153
LE + LV+ TRELA QI K YM GG +++ + + L+ P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166
Query: 154 HIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR-GFKDQIYEIFQKLNTSIQVVL 212
HIVVGTPGR+ + + L+ K IK F+LDE D+ML + + + EIF+ QV++
Sbjct: 167 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 226
Query: 213 LSATMPTDVLEVTKKFMRDPIRILVKKE-ELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
SAT+ ++ V +KFM+DP+ I V E +LTL G++Q+Y+ ++ E K L DL + L
Sbjct: 227 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 285
Query: 272 TITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTD 331
Q VIF+ + ++ L + + ++F A+H M Q+ER ++F+ R+L+ T+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345
Query: 332 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEE-DKRILRDIET 390
L RG+D+++V++ NYD+P + + Y+HR+ R GRFG KG+AI FV++E D +IL D++
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405
Query: 391 FYNTTVEEMP 400
+ + E+P
Sbjct: 406 RFEVNISELP 415
>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
sapiens]
Length = 427
Score = 259 bits (662), Expect = 3e-69
Identities = 143/373 (38%), Positives = 221/373 (59%), Gaps = 5/373 (1%)
Query: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
F D LK LLR I GFE PS +Q I I G DV+ QA+SG GKTA F ++ LQQ
Sbjct: 46 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 105
Query: 95 LEIEFKETQALVLAPTRELAQQIQKVILALGDYMGAT-CHACIGGTNVRNEMQKLQAEAP 153
+E + LV+ TRELA QI K YM + GG +++ + + L+ P
Sbjct: 106 IEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFGGLSIKKDEEVLKKNCP 165
Query: 154 HIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSR-GFKDQIYEIFQKLNTSIQVVL 212
H+VVGTPGR+ ++ R S K +K FVLDE D+ML + + + EIF+ Q ++
Sbjct: 166 HVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRDVQEIFRLTPHEKQCMM 225
Query: 213 LSATMPTDVLEVTKKFMRDPIRILVKKE-ELTLEGIKQFYINVEREEWKLDTLCDLYETL 271
SAT+ D+ V +KFM+DP+ + V E +LTL G++Q+Y+ ++ E K L DL + L
Sbjct: 226 FSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLKDSE-KNRKLFDLLDVL 284
Query: 272 TITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTD 331
Q +IF+ + ++ L + + ++F A+H M Q+ER ++F+ R+L+ T+
Sbjct: 285 EFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSRYQQFKDFQRRILVATN 344
Query: 332 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEE-DKRILRDIET 390
L RG+D+++V++V NYD+P + + Y+HR+ R GRFG KG+AI FV++E D +IL D++
Sbjct: 345 LFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 404
Query: 391 FYNTTVEEMPMNV 403
+ V E+P +
Sbjct: 405 RFEVNVAELPEEI 417
>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
sapiens]
Length = 483
Score = 256 bits (654), Expect = 3e-68
Identities = 149/380 (39%), Positives = 231/380 (60%), Gaps = 17/380 (4%)
Query: 32 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGY---DVIAQAQSGTGKTATFA 88
V F+++ LKE LL+GIYA GF +PS IQ+ A+ P + + ++IAQ+QSGTGKTA F
Sbjct: 96 VKTFEELRLKEELLKGIYAMGFNRPSKIQEMAL-PMMLAHPPQNLIAQSQSGTGKTAAFV 154
Query: 89 ISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDY-MGATCHACIGGTNVRNEMQK 147
+++L ++ Q L LAPT ELA Q +V+ +G + + I G N + +
Sbjct: 155 LAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRG----NRIPR 210
Query: 148 LQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEML-SRGFKDQIYEIFQKLN 205
I++GTPG V D + + + I++FVLDEAD M+ ++GF D I + L
Sbjct: 211 GTDITKQIIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALP 270
Query: 206 TSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLC 265
+ Q++L SAT V ++ + DP I ++KEELTL I+Q+Y+ E + K LC
Sbjct: 271 SECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALC 330
Query: 266 DLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSR 325
++Y ++TI QA+IF TRR WLT +M VS L G++ ++R I++ FR G +
Sbjct: 331 NIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEK 390
Query: 326 VLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINFVTE 379
VLITT++ ARGIDV+QV++V+N+DLP + E Y+HRIGR GRFG+KG+A N +
Sbjct: 391 VLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEV 450
Query: 380 EDKRILRDIETFYNTTVEEM 399
++ L I+ +N++++++
Sbjct: 451 DELPSLMKIQDHFNSSIKQL 470
>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
[Homo sapiens]
Length = 370
Score = 252 bits (643), Expect = 5e-67
Identities = 148/369 (40%), Positives = 226/369 (61%), Gaps = 18/369 (4%)
Query: 52 GFEKPSAIQQRAIIPCIKG--YDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAP 109
GF +PS IQ+ A+ + ++IAQ+QSGTGKTA F +++L Q+E K Q L L+P
Sbjct: 2 GFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSP 61
Query: 110 TRELAQQIQKVILALGDYMGAT--CHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDML 167
T ELA Q KVI +G + +A G N++++ Q + IV+GTPG V D
Sbjct: 62 TYELALQTGKVIEQMGKFYPELKLAYAVRG-----NKLERGQKISEQIVIGTPGTVLDWC 116
Query: 168 NR-RYLSPKWIKMFVLDEADEMLS-RGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVT 225
++ +++ PK IK+FVLDEAD M++ +G +DQ I + L + Q++L SAT V +
Sbjct: 117 SKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFA 176
Query: 226 KKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRK 285
+K + DP I +K+EE TL+ IKQ+Y+ + K LC+LY +TI QA+IF +TR+
Sbjct: 177 QKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKT 236
Query: 286 VDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLV 345
WL ++ V+ L G+M ++R ++ FR G +VL+TT++ ARGIDV+QVS+V
Sbjct: 237 ASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVV 296
Query: 346 INYDLPTNR------ENYIHRIGRGGRFGRKGVAINFV-TEEDKRILRDIETFYNTTVEE 398
IN+DLP ++ E Y+HRIGR GRFG++G+A+N V ++ IL I+ +N +E
Sbjct: 297 INFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIER 356
Query: 399 MPMNVADLI 407
+ + D I
Sbjct: 357 LDTDDLDEI 365
>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
[Homo sapiens]
Length = 448
Score = 244 bits (624), Expect = 8e-65
Identities = 141/347 (40%), Positives = 215/347 (61%), Gaps = 16/347 (4%)
Query: 72 DVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGAT 131
++IAQ+QSGTGKTA F +++L Q+E K Q L L+PT ELA Q KVI +G +
Sbjct: 102 NLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPEL 161
Query: 132 --CHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNR-RYLSPKWIKMFVLDEADEM 188
+A G N++++ Q + IV+GTPG V D ++ +++ PK IK+FVLDEAD M
Sbjct: 162 KLAYAVRG-----NKLERGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVM 216
Query: 189 LS-RGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGI 247
++ +G +DQ I + L + Q++L SAT V + +K + DP I +K+EE TL+ I
Sbjct: 217 IATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTI 276
Query: 248 KQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDM 307
KQ+Y+ + K LC+LY +TI QA+IF +TR+ WL ++ V+ L G+M
Sbjct: 277 KQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEM 336
Query: 308 DQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRI 361
++R ++ FR G +VL+TT++ ARGIDV+QVS+VIN+DLP ++ E Y+HRI
Sbjct: 337 MVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRI 396
Query: 362 GRGGRFGRKGVAINFV-TEEDKRILRDIETFYNTTVEEMPMNVADLI 407
GR GRFG++G+A+N V ++ IL I+ +N +E + + D I
Sbjct: 397 GRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 443
>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
sapiens]
Length = 824
Score = 244 bits (624), Expect = 8e-65
Identities = 141/364 (38%), Positives = 215/364 (59%), Gaps = 13/364 (3%)
Query: 34 NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 93
+F+ + L +L G+ A GFE+PS +Q +AI G D+I QA+SGTGKT F+ L
Sbjct: 63 DFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALD 122
Query: 94 QLEIEFKETQALVLAPTRELAQQIQKVILALGDYM-GATCHACIGGTNVRNEMQKLQAEA 152
L +E TQ L+LAPTRE+A QI VI A+G M G CH IGGT + + +L+
Sbjct: 123 SLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQDKTRLKK-- 180
Query: 153 PHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRG-FKDQIYEIFQKLNTSIQVV 211
HI VG+PGR+ ++ YL+P I++F+LDEAD++L G F++QI I+ L S Q++
Sbjct: 181 CHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQML 240
Query: 212 LLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVERE-------EWKLDTL 264
+SAT P + K+MRDP + + + +L G+KQ+Y V E K L
Sbjct: 241 AVSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHL 300
Query: 265 CDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSS 324
+L+ + QA++F N + L + + ++ F + G+M+Q +R M + +
Sbjct: 301 QELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHC 360
Query: 325 RVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVT--EEDK 382
RVLI+TDL +RGID ++V+LV+N D+P + E Y+HRIGR GRFG G+ + + EE+
Sbjct: 361 RVLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEEN 420
Query: 383 RILR 386
++R
Sbjct: 421 MMMR 424
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 209 bits (533), Expect = 3e-54
Identities = 129/390 (33%), Positives = 221/390 (56%), Gaps = 14/390 (3%)
Query: 9 NREHGGPEGMDPDGVIE--SNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIP 66
+R+ +G + G E S ++E + +F DMNL LL+ I A GF++P+ IQ+ I
Sbjct: 193 DRKKKKKKGQEAGGFFEDASQYDENL-SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPV 251
Query: 67 CIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKE---TQALVLAPTRELAQQIQKVILA 123
+ G D+ A A +GTGKTA FA+ +L++L + ++ T+ LVL PTREL Q+ V
Sbjct: 252 GLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQ 311
Query: 124 LGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRR---YLSPKWIKMF 180
L + T +GG +V+++ L+A AP I++ TPGR+ D L+ +LS I++
Sbjct: 312 LAQFCNITTCLAVGGLDVKSQEAALRA-APDILIATPGRLIDHLHNCPSFHLSS--IEVL 368
Query: 181 VLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 240
+LDEAD ML F++Q+ EI + + Q +L SATM +V ++ +++P+RI V
Sbjct: 369 ILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSN 428
Query: 241 ELTLEGIKQFYINVE-REEWKLDTLCDLYETLTITQAV-IFLNTRRKVDWLTEKMHARDF 298
++Q +I + E + + T T T V +F T+++ + +
Sbjct: 429 TDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGL 488
Query: 299 TVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYI 358
V LHG++ Q +R +R F+ +L+ TD+ ARG+D++ V VIN+ +P ++Y+
Sbjct: 489 QVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYV 548
Query: 359 HRIGRGGRFGRKGVAINFVTEEDKRILRDI 388
HR+GR R GR G +++ V E+++++L++I
Sbjct: 549 HRVGRTARAGRAGRSVSLVGEDERKMLKEI 578
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 207 bits (527), Expect = 1e-53
Identities = 127/381 (33%), Positives = 209/381 (54%), Gaps = 9/381 (2%)
Query: 11 EHGGP-EGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIK 69
EH P E P ++E E F D+ + + L G+ KP+ IQ AI ++
Sbjct: 6 EHDSPTEASQP--IVEE---EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ 60
Query: 70 GYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMG 129
G D+I A++G+GKT FA+ IL L + ALVL PTRELA QI + ALG +G
Sbjct: 61 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG 120
Query: 130 ATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDML-NRRYLSPKWIKMFVLDEADEM 188
+GG + ++ L A+ PHI++ TPGR+ D L N + + + +K V+DEAD +
Sbjct: 121 VQSAVIVGGIDSMSQSLAL-AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRI 179
Query: 189 LSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIK 248
L+ F+ ++ +I + + + L SATM V ++ + +++P++ V + T+E ++
Sbjct: 180 LNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQ 239
Query: 249 QFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMD 308
Q+YI + ++K L + L +IF +T + FT LHG M
Sbjct: 240 QYYIFIP-SKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMS 298
Query: 309 QKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFG 368
Q +R + +F++ + +L+ TD+ +RG+D+ V +V+N+D+PT+ ++YIHR+GR R G
Sbjct: 299 QSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAG 358
Query: 369 RKGVAINFVTEEDKRILRDIE 389
R G AI FVT+ D + + IE
Sbjct: 359 RSGKAITFVTQYDVELFQRIE 379
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 202 bits (514), Expect = 4e-52
Identities = 126/410 (30%), Positives = 211/410 (51%), Gaps = 38/410 (9%)
Query: 32 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISI 91
+ ++ D +L +L I G+++P+ IQ++AI ++ D+I A++G+GKTA F I +
Sbjct: 390 IRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPL 449
Query: 92 L---------QQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVR 142
L ++E + A++LAPTRELAQQI++ + G +G A IGG +
Sbjct: 450 LVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISRE 509
Query: 143 NEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQ 202
++ +L+ IV+ TPGR+ D+L RYL VLDEAD M+ GF+ + +I +
Sbjct: 510 DQGFRLRMGC-EIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILE 568
Query: 203 KLNTSIQ--------------------------VVLLSATMPTDVLEVTKKFMRDPIRIL 236
+ S Q V+ +ATMP V + + ++R P +
Sbjct: 569 HMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVY 628
Query: 237 VKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHAR 296
+ E ++Q + E K L + E +IF+N ++ D L + +
Sbjct: 629 IGSAGKPHERVEQKVFLMSESE-KRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKM 687
Query: 297 DFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNREN 356
+ LHG Q++R+ + ++G+ +L+ TD+ RGID+Q VS+V+NYD+ N E+
Sbjct: 688 GYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIED 747
Query: 357 YIHRIGRGGRFGRKGVAINFVTEEDKRILRDI-ETFYNTTVEEMPMNVAD 405
YIHRIGR GR G+ GVAI F+T+ED + ++ + + V P +A+
Sbjct: 748 YIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELAN 797
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 202 bits (513), Expect = 6e-52
Identities = 136/422 (32%), Positives = 224/422 (53%), Gaps = 28/422 (6%)
Query: 2 SGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQ 61
SGG+ N E ++ G SN ++NF D+++ E ++ I + +P+ +Q+
Sbjct: 150 SGGNTGINFEKYDDIPVEATG---SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206
Query: 62 RAIIPCIKGY-DVIAQAQSGTGKTATFAISILQQLEIE--------FKETQ--------- 103
AI P IKG D++A AQ+G+GKTA F + IL Q+ + KE
Sbjct: 207 HAI-PIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYP 265
Query: 104 -ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGR 162
+LVLAPTRELA QI + GG ++ +++ L+ H++V TPGR
Sbjct: 266 ISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGR 324
Query: 163 VFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV----LLSATMP 218
+ DM+ R + + K VLDEAD ML GF+ QI I ++ + V + SAT P
Sbjct: 325 LVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFP 384
Query: 219 TDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVI 278
++ + + F+ + I + V + T E I Q + VE + + L L T + + ++
Sbjct: 385 KEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLV 444
Query: 279 FLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGID 338
F+ T++ D L + ++ + +++HGD Q++R+ + +FRSG S +L+ T + ARG+D
Sbjct: 445 FVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLD 504
Query: 339 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEE 398
+ V VIN+DLP++ E Y+HRIGR GR G G+A +F E++ I +D+ +E
Sbjct: 505 ISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564
Query: 399 MP 400
+P
Sbjct: 565 VP 566
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 202 bits (513), Expect = 6e-52
Identities = 136/422 (32%), Positives = 224/422 (53%), Gaps = 28/422 (6%)
Query: 2 SGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQ 61
SGG+ N E ++ G SN ++NF D+++ E ++ I + +P+ +Q+
Sbjct: 150 SGGNTGINFEKYDDIPVEATG---SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQK 206
Query: 62 RAIIPCIKGY-DVIAQAQSGTGKTATFAISILQQLEIE--------FKETQ--------- 103
AI P IKG D++A AQ+G+GKTA F + IL Q+ + KE
Sbjct: 207 HAI-PIIKGKRDLMACAQTGSGKTAAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYP 265
Query: 104 -ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGR 162
+LVLAPTRELA QI + GG ++ +++ L+ H++V TPGR
Sbjct: 266 ISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGR 324
Query: 163 VFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV----LLSATMP 218
+ DM+ R + + K VLDEAD ML GF+ QI I ++ + V + SAT P
Sbjct: 325 LVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFP 384
Query: 219 TDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVI 278
++ + + F+ + I + V + T E I Q + VE + + L L T + + ++
Sbjct: 385 KEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLV 444
Query: 279 FLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGID 338
F+ T++ D L + ++ + +++HGD Q++R+ + +FRSG S +L+ T + ARG+D
Sbjct: 445 FVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLD 504
Query: 339 VQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEE 398
+ V VIN+DLP++ E Y+HRIGR GR G G+A +F E++ I +D+ +E
Sbjct: 505 ISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQE 564
Query: 399 MP 400
+P
Sbjct: 565 VP 566
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 201 bits (512), Expect = 8e-52
Identities = 119/353 (33%), Positives = 191/353 (54%), Gaps = 9/353 (2%)
Query: 44 LLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAIS----ILQQLEIEF 99
+L + +G+EKP+ IQ +AI + G D+I A++G+GKT F + I+ Q +E
Sbjct: 383 ILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMDQRSLEE 442
Query: 100 KETQ-ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVG 158
E A+++ PTRELA QI K +G GGT + ++ +L+ A I+V
Sbjct: 443 GEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGA-EIIVC 501
Query: 159 TPGRVFDML---NRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVLLSA 215
TPGR+ DML + R + + + VLDEAD M GF+ Q+ I + Q V+ SA
Sbjct: 502 TPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQTVMFSA 561
Query: 216 TMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQ 275
T P + + ++ + PI + V + ++Q I +E E+ L L L
Sbjct: 562 TFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLKLLELLGHYQESGS 621
Query: 276 AVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLAR 335
+IF++ + D L + + + +LHG +DQ +RD I+ +F++G+ ++L+ T + AR
Sbjct: 622 VIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNGTCKLLVATSVAAR 681
Query: 336 GIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI 388
G+DV+ + LV+NY P + E+Y+HR GR GR G KG A F+TE+ R DI
Sbjct: 682 GLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQARYAGDI 734
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 199 bits (506), Expect = 4e-51
Identities = 126/380 (33%), Positives = 204/380 (53%), Gaps = 10/380 (2%)
Query: 35 FDD-MNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAIS--- 90
FDD ++ I GF+KP+ IQ +A ++G D+I AQ+GTGKT + +
Sbjct: 243 FDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGFI 302
Query: 91 --ILQ-QLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQK 147
+LQ L+ + LVL PTRELA Q++ Y G GG N ++++
Sbjct: 303 HLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIEE 361
Query: 148 LQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTS 207
L+ + I++ TPGR+ D+ +++ K I VLDEAD+ML GF+ QI +I +
Sbjct: 362 LK-KGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRPD 420
Query: 208 IQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDL 267
Q V+ SAT P V + + ++++P+ + V +L + I V EE K +
Sbjct: 421 RQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQTF 480
Query: 268 YETLTITQAVIFLNTRRKV-DWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
++++ T VI +R+ V D L+ + + +V +LHGD +Q++R+ + F++G R+
Sbjct: 481 LQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVRI 540
Query: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
LI TDL +RG+DV V+ V N+D P N E Y+HRIGR GR GR GV+I +T D R+
Sbjct: 541 LIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVAS 600
Query: 387 DIETFYNTTVEEMPMNVADL 406
++ + +P + +
Sbjct: 601 ELINILERANQSIPEELVSM 620
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 196 bits (499), Expect = 2e-50
Identities = 113/372 (30%), Positives = 205/372 (55%), Gaps = 8/372 (2%)
Query: 34 NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 93
+F+ +L E L + G+E P+ IQ + I + G D++A A +G+GKTA F + ++
Sbjct: 204 DFEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLPVIM 263
Query: 94 QLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHAC-IGGTNVRNEMQKLQAEA 152
+ E K AL+L PTRELA QI++ L + +GG + ++ +LQ
Sbjct: 264 RALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQQHV 323
Query: 153 PHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVL 212
+++ TPGR+ D++ + + +K+ V+DEAD ML GF+ Q+ +I + + Q +L
Sbjct: 324 K-VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQTIL 382
Query: 213 LSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVE---REEWKLDTLCDLYE 269
+SAT+PT + ++ + + +P+RI+ ++ L ++Q + VE +++ + L D +
Sbjct: 383 VSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND--K 440
Query: 270 TLTITQAVIFLNTRRKVDWLTEKMHARDFTVS-ALHGDMDQKERDVIMREFRSGSSRVLI 328
L ++F++ + D L+E + S ++H + Q ER I++ G V++
Sbjct: 441 KLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYEVVV 500
Query: 329 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDI 388
+T +L RG+D+ V LV+N+D+P++ + Y+H+IGR GR G+ G AI F+ KR+ DI
Sbjct: 501 STGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLFWDI 560
Query: 389 ETFYNTTVEEMP 400
T +P
Sbjct: 561 AKRVKPTGSILP 572
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 196 bits (497), Expect = 4e-50
Identities = 130/421 (30%), Positives = 218/421 (51%), Gaps = 26/421 (6%)
Query: 2 SGGSADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQ 61
SGG+ N E ++ G +N +++F D+ + E ++ I + +P+ +Q+
Sbjct: 152 SGGNTGINFEKYDDIPVEATG---NNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQK 208
Query: 62 RAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLEIE--------FKETQ---------- 103
AI + D++A AQ+G+GKTA F + IL Q+ + KE
Sbjct: 209 HAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPI 268
Query: 104 ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRV 163
+LVLAPTRELA QI + GG ++ +++ L+ H++V TPGR+
Sbjct: 269 SLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGRL 327
Query: 164 FDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVV----LLSATMPT 219
DM+ R + + K VLDEAD ML GF+ QI I ++ + V + SAT P
Sbjct: 328 VDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPK 387
Query: 220 DVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLTITQAVIF 279
++ + + F+ + I + V + T E I Q + VE + + L L T + ++F
Sbjct: 388 EIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVF 447
Query: 280 LNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDV 339
+ T++ D L + ++ + +++HGD Q++R+ + +FRSG S +L+ T + ARG+D+
Sbjct: 448 VETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDI 507
Query: 340 QQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEM 399
V VIN+DLP++ E Y+HRIGR GR G G+A +F E + I +D+ +E+
Sbjct: 508 SNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEV 567
Query: 400 P 400
P
Sbjct: 568 P 568
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 195 bits (495), Expect = 7e-50
Identities = 126/371 (33%), Positives = 199/371 (53%), Gaps = 25/371 (6%)
Query: 34 NFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQ 93
NF + N +++ I F +P+AIQ + + G D++ AQ+G+GKT ++ + +
Sbjct: 95 NFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIV 154
Query: 94 QLEIE-FKETQ----ALVLAPTRELAQQIQKVILALGDYMGATCHAC-------IGGTNV 141
+ + F E LVLAPTRELAQQ+Q+V +Y C AC GG
Sbjct: 155 HINHQPFLERGDGPICLVLAPTRELAQQVQQVA---AEY----CRACRLKSTCIYGGAPK 207
Query: 142 RNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIF 201
+++ L+ I + TPGR+ D L + + VLDEAD ML GF+ QI +I
Sbjct: 208 GPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIV 266
Query: 202 QKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEG----IKQFYINVERE 257
++ Q ++ SAT P +V ++ + F++D I I + EL+ I +VE++
Sbjct: 267 DQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKD 326
Query: 258 EWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMR 317
E KL L + + + ++F+ T+R+ D LT KM + +HGD Q+ERD ++
Sbjct: 327 E-KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLN 385
Query: 318 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFV 377
EF+ G + +LI TD+ +RG+DV+ V VINYD P + E+YIHRIGR R + G A F
Sbjct: 386 EFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFF 445
Query: 378 TEEDKRILRDI 388
T + + + D+
Sbjct: 446 TPNNIKQVSDL 456
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 192 bits (489), Expect = 4e-49
Identities = 119/385 (30%), Positives = 200/385 (51%), Gaps = 20/385 (5%)
Query: 32 VDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISI 91
+ +F +M ++LRG+ G P+ IQ + I + G D+I A +G+GKT F + +
Sbjct: 180 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 239
Query: 92 L-----QQLEIEFKETQA---LVLAPTRELAQQIQKVI------LALGDYMGATCHACIG 137
+ Q+ + F + + L++ P+RELA+Q ++ L C CIG
Sbjct: 240 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 299
Query: 138 GTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQI 197
G +V+ +M+ ++ H++V TPGR+ D+L ++ +S + LDEAD M+ GF+ I
Sbjct: 300 GMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDI 358
Query: 198 YEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE-ELTLEGIKQFYINVER 256
IF Q +L SATMP + K + P+ I V + +L+ I++ + +
Sbjct: 359 RTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQE--VEYVK 416
Query: 257 EEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIM 316
EE K+ L + + T +IF + VD + E + + A+HG DQ+ER +
Sbjct: 417 EEAKMVYLLECLQK-TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAI 475
Query: 317 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINF 376
FR G VL+ TD+ ++G+D + VINYD+P ENY+HRIGR GR G G+A F
Sbjct: 476 EAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTF 535
Query: 377 VTEE-DKRILRDIETFYNTTVEEMP 400
+ + D+ +L D++ +++P
Sbjct: 536 INKACDESVLMDLKALLLEAKQKVP 560
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 192 bits (489), Expect = 4e-49
Identities = 115/361 (31%), Positives = 191/361 (52%), Gaps = 6/361 (1%)
Query: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
F M L + +GI G++ P+ IQ++ I + G DV+A A++G+GKTA F + + ++
Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157
Query: 95 LEIEFKET--QALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEA 152
L+ +T +AL+L+PTRELA Q K LG + G +GG + ++ L E
Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALH-EN 216
Query: 153 PHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVL 212
P I++ TPGR+ + L + ++ V DEAD + GF +Q+ EI +L Q VL
Sbjct: 217 PDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVL 276
Query: 213 LSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLT 272
SAT+P ++E + + +P+ I + + E +K + V RE+ K L L +
Sbjct: 277 FSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV-REDTKAAVLLHLLHNVV 335
Query: 273 ITQ--AVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITT 330
Q V+F+ T+ ++LTE + + + + ++ +D R + + +F G LI T
Sbjct: 336 RPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395
Query: 331 DLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIET 390
DL ARG+D+ + VINY P + ++HR+GR R GR G A + V ++ L D+
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHL 455
Query: 391 F 391
F
Sbjct: 456 F 456
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 192 bits (489), Expect = 4e-49
Identities = 115/361 (31%), Positives = 191/361 (52%), Gaps = 6/361 (1%)
Query: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
F M L + +GI G++ P+ IQ++ I + G DV+A A++G+GKTA F + + ++
Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157
Query: 95 LEIEFKET--QALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEA 152
L+ +T +AL+L+PTRELA Q K LG + G +GG + ++ L E
Sbjct: 158 LKTHSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALH-EN 216
Query: 153 PHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQVVL 212
P I++ TPGR+ + L + ++ V DEAD + GF +Q+ EI +L Q VL
Sbjct: 217 PDIIIATPGRLVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVL 276
Query: 213 LSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYETLT 272
SAT+P ++E + + +P+ I + + E +K + V RE+ K L L +
Sbjct: 277 FSATLPKLLVEFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV-REDTKAAVLLHLLHNVV 335
Query: 273 ITQ--AVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRVLITT 330
Q V+F+ T+ ++LTE + + + + ++ +D R + + +F G LI T
Sbjct: 336 RPQDQTVVFVATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVT 395
Query: 331 DLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILRDIET 390
DL ARG+D+ + VINY P + ++HR+GR R GR G A + V ++ L D+
Sbjct: 396 DLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHL 455
Query: 391 F 391
F
Sbjct: 456 F 456
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 191 bits (486), Expect = 8e-49
Identities = 121/362 (33%), Positives = 188/362 (51%), Gaps = 9/362 (2%)
Query: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
F N + ++ + F +P+ IQ + + G D++ AQ+G+GKT + + +
Sbjct: 173 FHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVH 232
Query: 95 LEIE-FKETQ----ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 149
+ + + E LVLAPTRELAQQ+Q+V G GG +++ L+
Sbjct: 233 INHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
Query: 150 AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 209
I + TPGR+ D L + + VLDEAD ML GF+ QI +I ++ Q
Sbjct: 293 -RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQ 351
Query: 210 VVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYE 269
++ SAT P +V ++ + F+RD +I V EL+ ++V E K L L E
Sbjct: 352 TLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLME 411
Query: 270 TLTI---TQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
+ + +IF+ T+R+ D LT +M + +HGD Q ERD ++ EFRSG + +
Sbjct: 412 EIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPI 471
Query: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
LI TD+ +RG+DV+ V VINYD P + E+Y+HRIGR R KG A F T + + R
Sbjct: 472 LIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAR 531
Query: 387 DI 388
++
Sbjct: 532 EL 533
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 191 bits (486), Expect = 8e-49
Identities = 121/362 (33%), Positives = 188/362 (51%), Gaps = 9/362 (2%)
Query: 35 FDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQ 94
F N + ++ + F +P+ IQ + + G D++ AQ+G+GKT + + +
Sbjct: 173 FHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVH 232
Query: 95 LEIE-FKETQ----ALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 149
+ + + E LVLAPTRELAQQ+Q+V G GG +++ L+
Sbjct: 233 INHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLE 292
Query: 150 AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 209
I + TPGR+ D L + + VLDEAD ML GF+ QI +I ++ Q
Sbjct: 293 -RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQ 351
Query: 210 VVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCDLYE 269
++ SAT P +V ++ + F+RD +I V EL+ ++V E K L L E
Sbjct: 352 TLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQLME 411
Query: 270 TLTI---TQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
+ + +IF+ T+R+ D LT +M + +HGD Q ERD ++ EFRSG + +
Sbjct: 412 EIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPI 471
Query: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
LI TD+ +RG+DV+ V VINYD P + E+Y+HRIGR R KG A F T + + R
Sbjct: 472 LIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQAR 531
Query: 387 DI 388
++
Sbjct: 532 EL 533
>gi|38569503 ATP-dependent RNA helicase ROK1 isoform b [Homo
sapiens]
Length = 491
Score = 181 bits (460), Expect = 8e-46
Identities = 119/362 (32%), Positives = 192/362 (53%), Gaps = 13/362 (3%)
Query: 37 DMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLE 96
+ + LL+ I GF+ P+ IQ +AI + G +++A A +G+GKT F+I IL QL+
Sbjct: 61 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 120
Query: 97 IEF-KETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHI 155
K +AL+++PTRELA QI + ++ + + G H + ++ I
Sbjct: 121 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 180
Query: 156 VVGTPGRVFDMLNRR-----YLSPKWIKMFVLDEADEMLS---RGFKDQIYEIFQKLNT- 206
+V TP R+ +L + S +W+ V+DE+D++ GF+DQ+ IF +
Sbjct: 181 LVTTPNRLIYLLKQDPPGIDLASVEWL---VVDESDKLFEDGKTGFRDQLASIFLACTSH 237
Query: 207 SIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCD 266
++ + SAT DV + K + + I + + +E ++Q + V E KL + +
Sbjct: 238 KVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRE 297
Query: 267 LYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
L + ++F+ + + L ++ V +H + Q++RD + FR+G V
Sbjct: 298 LVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWV 357
Query: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
LI T LLARGID + V+LVINYD PT+ YIHRIGR GR G KG AI F TE+DK +LR
Sbjct: 358 LICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLR 417
Query: 387 DI 388
+
Sbjct: 418 SV 419
>gi|38569505 ATP-dependent RNA helicase ROK1 isoform a [Homo
sapiens]
Length = 599
Score = 181 bits (460), Expect = 8e-46
Identities = 119/362 (32%), Positives = 192/362 (53%), Gaps = 13/362 (3%)
Query: 37 DMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAISILQQLE 96
+ + LL+ I GF+ P+ IQ +AI + G +++A A +G+GKT F+I IL QL+
Sbjct: 169 EYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLASAPTGSGKTLAFSIPILMQLK 228
Query: 97 IEF-KETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQAEAPHI 155
K +AL+++PTRELA QI + ++ + + G H + ++ I
Sbjct: 229 QPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHMIHKAAVAAKKFGPKSSKKFDI 288
Query: 156 VVGTPGRVFDMLNRR-----YLSPKWIKMFVLDEADEMLS---RGFKDQIYEIFQKLNT- 206
+V TP R+ +L + S +W+ V+DE+D++ GF+DQ+ IF +
Sbjct: 289 LVTTPNRLIYLLKQDPPGIDLASVEWL---VVDESDKLFEDGKTGFRDQLASIFLACTSH 345
Query: 207 SIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTLEGIKQFYINVEREEWKLDTLCD 266
++ + SAT DV + K + + I + + +E ++Q + V E KL + +
Sbjct: 346 KVRRAMFSATFAYDVEQWCKLNLDNVISVSIGARNSAVETVEQELLFVGSETGKLLAMRE 405
Query: 267 LYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALHGDMDQKERDVIMREFRSGSSRV 326
L + ++F+ + + L ++ V +H + Q++RD + FR+G V
Sbjct: 406 LVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQQRDNTVHSFRAGKIWV 465
Query: 327 LITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINFVTEEDKRILR 386
LI T LLARGID + V+LVINYD PT+ YIHRIGR GR G KG AI F TE+DK +LR
Sbjct: 466 LICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAGNKGKAITFFTEDDKPLLR 525
Query: 387 DI 388
+
Sbjct: 526 SV 527
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.395
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,974,388
Number of Sequences: 37866
Number of extensions: 566155
Number of successful extensions: 1532
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 69
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1284
Number of HSP's gapped (non-prelim): 100
length of query: 407
length of database: 18,247,518
effective HSP length: 105
effective length of query: 302
effective length of database: 14,271,588
effective search space: 4310019576
effective search space used: 4310019576
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.