Guide to the Human Genome
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Search of human proteins with 83320070

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83320070 gasdermin D [Homo sapiens]
         (484 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83320070 gasdermin D [Homo sapiens]                                968   0.0  
gi|150456463 gasdermin 1 [Homo sapiens]                               196   4e-50
gi|13899221 melanoma-derived leucine zipper, extra-nuclear facto...   174   1e-43
gi|109689703 gasdermin-like isoform 1 [Homo sapiens]                   88   2e-17
gi|109689711 gasdermin-like isoform 2 [Homo sapiens]                   85   2e-16
gi|4758154 deafness, autosomal dominant 5 protein isoform a [Hom...    58   2e-08
gi|188536092 deafness, autosomal dominant 5 protein isoform a [H...    58   2e-08
gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]           50   6e-06
gi|18250298 src-related kinase lacking C-terminal regulatory tyr...    34   0.26 
gi|92091575 coiled-coil domain containing 57 [Homo sapiens]            33   0.76 
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]       32   0.99 
gi|70780384 protease inhibitor 16 precursor [Homo sapiens]             32   0.99 
gi|229892328 IQ motif containing C isoform 1 [Homo sapiens]            32   1.3  
gi|238908495 similar to pleckstrin homology domain protein (5V32...    32   1.7  
gi|239753475 PREDICTED: hypothetical protein [Homo sapiens]            32   1.7  
gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo ...    32   1.7  
gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo ...    32   1.7  
gi|75677365 dynein heavy chain domain 3 [Homo sapiens]                 32   1.7  
gi|7705638 bolA-like 1 [Homo sapiens]                                  31   2.2  
gi|109715835 HEAT repeat containing 6 [Homo sapiens]                   30   3.8  
gi|34452725 polypeptide N-acetylgalactosaminyltransferase 4 [Hom...    30   4.9  
gi|73695473 roquin [Homo sapiens]                                      30   4.9  
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    30   6.4  
gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]             30   6.4  
gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain...    30   6.4  
gi|187608767 E74-like factor 4 [Homo sapiens]                          29   8.4  
gi|4503555 E74-like factor 4 [Homo sapiens]                            29   8.4  
gi|47086907 lysophosphatidylcholine acyltransferase 2 [Homo sapi...    29   8.4  
gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]     29   8.4  
gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]    29   8.4  

>gi|83320070 gasdermin D [Homo sapiens]
          Length = 484

 Score =  968 bits (2503), Expect = 0.0
 Identities = 484/484 (100%), Positives = 484/484 (100%)

Query: 1   MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS 60
           MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS
Sbjct: 1   MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS 60

Query: 61  IKDILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNV 120
           IKDILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNV
Sbjct: 61  IKDILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNV 120

Query: 121 YSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREG 180
           YSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREG
Sbjct: 121 YSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREG 180

Query: 181 SGRFSLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKKQRTF 240
           SGRFSLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKKQRTF
Sbjct: 181 SGRFSLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKKQRTF 240

Query: 241 QPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKE 300
           QPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKE
Sbjct: 241 QPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKE 300

Query: 301 LELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSS 360
           LELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSS
Sbjct: 301 LELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSS 360

Query: 361 GMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERST 420
           GMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERST
Sbjct: 361 GMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERST 420

Query: 421 MSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLS 480
           MSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLS
Sbjct: 421 MSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLS 480

Query: 481 QEPH 484
           QEPH
Sbjct: 481 QEPH 484


>gi|150456463 gasdermin 1 [Homo sapiens]
          Length = 445

 Score =  196 bits (498), Expect = 4e-50
 Identities = 156/480 (32%), Positives = 239/480 (49%), Gaps = 43/480 (8%)

Query: 5   FERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLSIKDI 64
           FE V R + ++L+  G+  P+ SL     F P+CLV+RK  S+ FW  RY   + ++ D+
Sbjct: 4   FENVTRALARQLNPRGDLTPLDSLIDFKRFHPFCLVLRKRKSTLFWGARYVRTDYTLLDV 63

Query: 65  LEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNVYSLS 124
           LEP ++  D     +F F + +D +++G V++  P   K+ G A +S +S  ++ V +LS
Sbjct: 64  LEPGSSPSDPTDTGNFGFKNMLDTRVEGDVDV--PKTVKVKGTAGLSQNS--TLEVQTLS 119

Query: 125 VDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREGSGRF 184
           V P   +T + ER L   +H  L++++ +G+N+YVV EV++T +EV + R  K E    F
Sbjct: 120 VAPKALET-VQERKL-AADHPFLKEMQDQGENLYVVMEVVETVQEVTLERAGKAEAC--F 175

Query: 185 SLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVI--DSDLDVLLFPDKKQRTFQP 242
           SLP    L    QG ++ K+ VTIP G  LAFRV QL++    + D+    +   +TF P
Sbjct: 176 SLPFFAPL--GLQGSINHKEAVTIPKGCVLAFRVRQLMVKGKDEWDIPHICNDNMQTFPP 233

Query: 243 PATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKELE 302
              G K    +    Q                      G   E F+ L+ EV+  ++++E
Sbjct: 234 ---GEKSGEEKVILIQASD------------------VGDVHEGFRTLKEEVQRETQQVE 272

Query: 303 LLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGM 362
            L R     LL  L  +L  +  L+ LE ALE          LD      LE L     +
Sbjct: 273 KLSRVGQSSLLSSLSKLLGKKKELQDLELALEGA--------LDKGHEVTLEALP-KDVL 323

Query: 363 LVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERSTMS 422
           L  E    ++Y +GALT LSE Q KLL +++E + L   L+LV S +EQ+    +     
Sbjct: 324 LSKEAVGAILYFVGALTELSEAQQKLLVKSMEKKILPVQLKLVESTMEQNFLLDKEGVFP 383

Query: 423 LPPGLLGNSWGEGAP-AWVLLDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLSQ 481
           L P LL +   E       L+   GLE+    P   W+P    R+CALYA L+LL  L++
Sbjct: 384 LQPELLSSLGDEELTLTEALVGLSGLEVQRSGPQYMWDPDTLPRLCALYAGLSLLQQLTK 443


>gi|13899221 melanoma-derived leucine zipper, extra-nuclear factor
           [Homo sapiens]
          Length = 508

 Score =  174 bits (442), Expect = 1e-43
 Identities = 157/520 (30%), Positives = 251/520 (48%), Gaps = 52/520 (10%)

Query: 1   MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSS-SWFWKPR-YKCVN 58
           M S  ER+ + +V+E+    +  PV  L S+T  + + ++ +K  S S FW+   Y  V 
Sbjct: 1   MPSMLERISKNLVKEIG-SKDLTPVKYLLSATKLRQFVILRKKKDSRSSFWEQSDYVPVE 59

Query: 59  LSIKDILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSM 118
            S+ DILEP ++  +      FHF D M  + +  + +    +  ++G A+V    S   
Sbjct: 60  FSLNDILEPSSSVLETVVTGPFHFSDIMIQKHKADMGVNVGIEVSVSGEASVDHGCSLEF 119

Query: 119 NVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKR 178
            + ++   PN       +R L  PE   L++ R RGDN+YVVTE ++      +  +   
Sbjct: 120 QIVTIP-SPNLED--FQKRKLLDPEPSFLKECRRRGDNLYVVTEAVELINNTVLYDSSSV 176

Query: 179 EGSGRFSLPGATCLQGEGQGHLSQ--KKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKK 236
              G+ +L   T  +G+GQG   +  KK +T+  G  +A++  QLVI  +  +L+  D +
Sbjct: 177 NILGKIAL-WITYGKGQGQGESLRVKKKALTLQKGMVMAYKRKQLVI-KEKAILISDDDE 234

Query: 237 QRTFQPP-----ATGHKRSTSEGAWPQLPSGLSMMRCLHN-----------------FLT 274
           QRTFQ         G+  + SEG    LPS  ++   L N                 FL+
Sbjct: 235 QRTFQDEYEISEMVGYCAARSEGL---LPSFHTISPTLFNASSNDMKLKPELFLTQQFLS 291

Query: 275 DGVPA------------EGAFTEDFQGLRAEVETISKELELLDRELCQLLLEGLEGVLRD 322
             +P             E  F ++F+ L+ EV    K L  L +++  ++   +  +LRD
Sbjct: 292 GHLPKYEQVHILPVGRIEEPFWQNFKHLQEEVFQKIKTLAQLSKDVQDVMFYSILAMLRD 351

Query: 323 QLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGMLVPELAIPVVYLLGALTMLS 382
           + AL+ L   LE   S      LDGP GA+L+ L   S         P++YLL A+ +LS
Sbjct: 352 RGALQDLMNMLELDSS----GHLDGPGGAILKKLQQDSNHAWFNPKDPILYLLEAIMVLS 407

Query: 383 ETQHKLLAEALESQTLLGPLELVGSLLEQSAPWQERSTMSLPPGLLGNSWGEG-APAWVL 441
           + QH LLA ++E + LL   ELV S+LE +  +      +L P LL     EG A  + L
Sbjct: 408 DFQHDLLACSMEKRILLQQQELVRSILEPNFRYPWSIPFTLKPELLAPLQSEGLAITYGL 467

Query: 442 LDECGLELGEDTPHVCWEPQAQGRMCALYASLALLSGLSQ 481
           L+ECGL +  D P   W+ +A+  + ALY +L+LL  L++
Sbjct: 468 LEECGLRMELDNPRSTWDVEAKMPLSALYGTLSLLQQLAE 507


>gi|109689703 gasdermin-like isoform 1 [Homo sapiens]
          Length = 403

 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 122/494 (24%), Positives = 207/494 (41%), Gaps = 107/494 (21%)

Query: 1   MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS 60
           M S FE + R VV+E+D GG+ I V SL  +  F+ + LV  K +   F+  R+    L+
Sbjct: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLT 57

Query: 61  IKDILEPDAAE--PDVQRG-----RSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDS 113
           + DIL+ D  +   ++  G       F   D +D    G + +  P +  I+G       
Sbjct: 58  LMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDS--TGELIVRLPKEITISGSFQGFHH 115

Query: 114 SSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVT 173
               ++   +S     +   L  R L++      + + +R +N+Y+VTE L+T KE  + 
Sbjct: 116 QKIKISENRIS---QQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLK 171

Query: 174 RTHKREGSGRFSLPGATCLQGEGQGHLSQK----KTVTIPSGSTLAFRVAQLVIDSDLDV 229
              + +   + S           QGHLS K    + VTIP    L++RV QLV       
Sbjct: 172 SDRQYKFWSQIS-----------QGHLSYKHKGQREVTIPPNRVLSYRVKQLV------- 213

Query: 230 LLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQG 289
             FP+K            +    +GA   L   L                    +ED + 
Sbjct: 214 --FPNK------------ETMKKDGASSCLGKSLG-------------------SEDSRN 240

Query: 290 LRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPA 349
           ++ ++E +   L+ L  E  + +L  L   L  +   + LE+ + +    G +  ++ P 
Sbjct: 241 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH-MEDPD 299

Query: 350 GAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLL 409
             +L  L  ++G+LV   A  ++  L AL  LSE Q + +AEALE  TL    + V S++
Sbjct: 300 KPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQ-QFVAEALEKGTLPLLKDQVKSVM 358

Query: 410 EQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCAL 469
           EQ+  W                                EL    P + ++P+A+  +CAL
Sbjct: 359 EQN--WD-------------------------------ELASSPPDMDYDPEAR-ILCAL 384

Query: 470 YASLALLSGLSQEP 483
           Y  +++L  L++ P
Sbjct: 385 YVVVSILLELAEGP 398


>gi|109689711 gasdermin-like isoform 2 [Homo sapiens]
          Length = 394

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 120/494 (24%), Positives = 206/494 (41%), Gaps = 116/494 (23%)

Query: 1   MGSAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVNLS 60
           M S FE + R VV+E+D GG+ I V SL  +  F+ + LV  K +   F+  R+    L+
Sbjct: 1   MFSVFEEITRIVVKEMDAGGDMIAVRSLVDADRFRCFHLVGEKRT---FFGCRHYTTGLT 57

Query: 61  IKDILEPDAAE--PDVQRG-----RSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDS 113
           + DIL+ D  +   ++  G       F   D +D    G + +  P +  I+G       
Sbjct: 58  LMDILDTDGDKWLDELDSGLQGQKAEFQILDNVDS--TGELIVRLPKEITISGSFQGFHH 115

Query: 114 SSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQKEVEVT 173
               ++   +S     +   L  R L++      + + +R +N+Y+VTE L+T KE  + 
Sbjct: 116 QKIKISENRIS---QQYLATLENRKLKRELPFSFRSINTR-ENLYLVTETLETVKEETLK 171

Query: 174 RTHKREGSGRFSLPGATCLQGEGQGHLSQK----KTVTIPSGSTLAFRVAQLVIDSDLDV 229
              + +   + S           QGHLS K    + VTIP    L++RV QLV       
Sbjct: 172 SDRQYKFWSQIS-----------QGHLSYKHKGQREVTIPPNRVLSYRVKQLV------- 213

Query: 230 LLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGAFTEDFQG 289
             FP+K+                           +M + L              +ED + 
Sbjct: 214 --FPNKE---------------------------TMRKSLG-------------SEDSRN 231

Query: 290 LRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPA 349
           ++ ++E +   L+ L  E  + +L  L   L  +   + LE+ + +    G +  ++ P 
Sbjct: 232 MKEKLEDMESVLKDLTEEKRKDVLNSLAKCLGKEDIRQDLEQRVSEVLISGELH-MEDPD 290

Query: 350 GAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLL 409
             +L  L  ++G+LV   A  ++  L AL  LSE Q + +AEALE  TL    + V S++
Sbjct: 291 KPLLSSLFNAAGVLVEARAKAILDFLDALLELSEEQ-QFVAEALEKGTLPLLKDQVKSVM 349

Query: 410 EQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQAQGRMCAL 469
           EQ+  W                                EL    P + ++P+A+  +CAL
Sbjct: 350 EQN--WD-------------------------------ELASSPPDMDYDPEAR-ILCAL 375

Query: 470 YASLALLSGLSQEP 483
           Y  +++L  L++ P
Sbjct: 376 YVVVSILLELAEGP 389


>gi|4758154 deafness, autosomal dominant 5 protein isoform a [Homo
           sapiens]
          Length = 496

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 84/352 (23%), Positives = 150/352 (42%), Gaps = 55/352 (15%)

Query: 5   FERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFW-KPRYKCVNLSIKD 63
           F +  R  ++E+D  G+ I V++L  S   Q   LV +K    W W +P+Y+ ++L++ D
Sbjct: 2   FAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKK-KRFWCWQRPKYQFLSLTLGD 60

Query: 64  ILEPDAAEPDVQRGRSFHFYDA-MDGQIQGSVELAAPGQAKI-AGGAAVSDSSSTSMNVY 121
           +L  D     V     F  Y+      + G++E A  G+ K+  GG++  +S S+   + 
Sbjct: 61  VLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETAL-GKVKLNLGGSSRVESQSSFGTLR 119

Query: 122 SLSVDPNTWQTLLHER-----HLRQPEHKVLQQ-LRSRGDNVYVVTEVLQTQKEVEVTRT 175
              VD    Q L+ +      +LR P   VLQQ L  R + + V+T+ + T ++  ++  
Sbjct: 120 KQEVD---LQQLIRDSAERTINLRNP---VLQQVLEGRNEVLCVLTQKITTMQKCVISEH 173

Query: 176 HKREG--SGRFSLPGATC-LQGEGQGHLSQKKTVT--IPSGSTLAFRVAQLVIDSD---- 226
            + E    G   +   T  +     G++++   V   IP+ +T+A+ V +L +  D    
Sbjct: 174 MQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFE 233

Query: 227 ---------------------LDVLLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSG-LS 264
                                LD L+F  ++      P   H  S+ +G    L    L 
Sbjct: 234 FCLLRGKQGGFENKKRIDSVYLDPLVF--REFAFIDMPDAAHGISSQDGPLSVLKQATLL 291

Query: 265 MMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKELELLDRELCQLLLEGL 316
           + R  H F     P + A ++ FQ +         EL ++   +C  L+ GL
Sbjct: 292 LERNFHPFAELPEPQQTALSDIFQAV-----LFDDELLMVLEPVCDDLVSGL 338


>gi|188536092 deafness, autosomal dominant 5 protein isoform a [Homo
           sapiens]
          Length = 496

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 84/352 (23%), Positives = 150/352 (42%), Gaps = 55/352 (15%)

Query: 5   FERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFW-KPRYKCVNLSIKD 63
           F +  R  ++E+D  G+ I V++L  S   Q   LV +K    W W +P+Y+ ++L++ D
Sbjct: 2   FAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKK-KRFWCWQRPKYQFLSLTLGD 60

Query: 64  ILEPDAAEPDVQRGRSFHFYDA-MDGQIQGSVELAAPGQAKI-AGGAAVSDSSSTSMNVY 121
           +L  D     V     F  Y+      + G++E A  G+ K+  GG++  +S S+   + 
Sbjct: 61  VLIEDQFPSPVVVESDFVKYEGKFANHVSGTLETAL-GKVKLNLGGSSRVESQSSFGTLR 119

Query: 122 SLSVDPNTWQTLLHER-----HLRQPEHKVLQQ-LRSRGDNVYVVTEVLQTQKEVEVTRT 175
              VD    Q L+ +      +LR P   VLQQ L  R + + V+T+ + T ++  ++  
Sbjct: 120 KQEVD---LQQLIRDSAERTINLRNP---VLQQVLEGRNEVLCVLTQKITTMQKCVISEH 173

Query: 176 HKREG--SGRFSLPGATC-LQGEGQGHLSQKKTVT--IPSGSTLAFRVAQLVIDSD---- 226
            + E    G   +   T  +     G++++   V   IP+ +T+A+ V +L +  D    
Sbjct: 174 MQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFE 233

Query: 227 ---------------------LDVLLFPDKKQRTFQPPATGHKRSTSEGAWPQLPSG-LS 264
                                LD L+F  ++      P   H  S+ +G    L    L 
Sbjct: 234 FCLLRGKQGGFENKKRIDSVYLDPLVF--REFAFIDMPDAAHGISSQDGPLSVLKQATLL 291

Query: 265 MMRCLHNFLTDGVPAEGAFTEDFQGLRAEVETISKELELLDRELCQLLLEGL 316
           + R  H F     P + A ++ FQ +         EL ++   +C  L+ GL
Sbjct: 292 LERNFHPFAELPEPQQTALSDIFQAV-----LFDDELLMVLEPVCDDLVSGL 338


>gi|111607457 deafness, autosomal recessive 59 [Homo sapiens]
          Length = 352

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 60/232 (25%), Positives = 104/232 (44%), Gaps = 24/232 (10%)

Query: 5   FERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWFWKPRYKCVN--LSIK 62
           F    +  V+++  GG  +PV SL  +  +QP  LVV+K     F  PRYK  +   ++K
Sbjct: 2   FAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLF--PRYKFTSTPFTLK 59

Query: 63  DILEPDAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAKIAGGAAVSDSSSTSMNVYS 122
           DIL  D    ++  G S   Y  ++ + +  V L       I     ++ + S S+ V +
Sbjct: 60  DILLGDR---EISAGIS--SYQLLNYEDESDVSLYGRRGNHIVNDVGINVAGSDSIAVKA 114

Query: 123 ----LSVDPNTWQTLLHERHLRQP--EHKVLQQLR-SRGDNVYVVTEVLQTQKEVEVT-R 174
               ++       TLL E   R+   +H +++Q R SR   + VV E ++T ++  ++  
Sbjct: 115 SFGIVTKHEVEVSTLLKEITTRKINFDHSLIRQSRSSRKAVLCVVMESIRTTRQCSLSVH 174

Query: 175 THKREGSGRFSLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSD 226
              R  + RF          + Q    + K +  P+ +T+AF V +L I  D
Sbjct: 175 AGIRGEAMRFHFM-------DEQNPKGRDKAIVFPAHTTIAFSVFELFIYLD 219


>gi|18250298 src-related kinase lacking C-terminal regulatory
           tyrosine and N-terminal myristylation sites [Homo
           sapiens]
          Length = 488

 Score = 34.3 bits (77), Expect = 0.26
 Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 6/98 (6%)

Query: 109 AVSDSSSTSMNVYSLSVDPNTWQTLLHERHLRQPEHKVLQQLRSRGDNVYVVTEVLQTQK 168
           A+    S +M +  L+ +  T + L HER +R      L  + S G+ VY+VTE+++   
Sbjct: 256 AIKVIKSANMKLTDLAKEIQTLKGLRHERLIR------LHAVCSGGEPVYIVTELMRKGN 309

Query: 169 EVEVTRTHKREGSGRFSLPGATCLQGEGQGHLSQKKTV 206
                 T +        L G  C   EG  +L +++ V
Sbjct: 310 LQAFLGTPEGRALRLPPLLGFACQVAEGMSYLEEQRVV 347


>gi|92091575 coiled-coil domain containing 57 [Homo sapiens]
          Length = 915

 Score = 32.7 bits (73), Expect = 0.76
 Identities = 44/158 (27%), Positives = 69/158 (43%), Gaps = 27/158 (17%)

Query: 51  KPRYKCVNLSIKDILEP-------DAAEPDVQRGRSFHFYDAMDGQIQGSVELAAPGQAK 103
           K ++K +   ++D+L+P         ++P V+         A  GQ  GSV      QA 
Sbjct: 590 KHKFKTLEKHLEDVLDPLKMSSPHAESQPSVRTSTETTGGSAQAGQAGGSV------QAG 643

Query: 104 IAGGAAVSDSSSTSMNVYSLSVDP---NTWQTLLHERHLRQP-EHKVLQ-QLRSRGDNVY 158
            AGG+  +   S+ + +  L       N   T L ++ LR+P E   LQ +L    D V+
Sbjct: 644 QAGGSVQAGPVSSGLALRKLGDRVQLLNLLVTRLRQKVLREPLEPAALQRELPREVDQVH 703

Query: 159 VVTEVLQTQKEVEVTRTHKR-------EGSGRFSLPGA 189
           +  EVL+ +K+V     H R       E SGR   P +
Sbjct: 704 L--EVLELRKQVAELGKHLRIAQHGGAEPSGRKQPPAS 739


>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
          Length = 1191

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 6/47 (12%)

Query: 3    SAFERVVRRVVQELDHGGEFIPVTSLQSSTGFQPYCLVVRKPSSSWF 49
            +A ERV     Q  D   EF P+ SLQ S G+Q  C     PS++W+
Sbjct: 1103 TATERVQNGCAQPRDRDSEFTPLASLQ-SPGYQSTC-----PSAAWY 1143


>gi|70780384 protease inhibitor 16 precursor [Homo sapiens]
          Length = 463

 Score = 32.3 bits (72), Expect = 0.99
 Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 27/160 (16%)

Query: 119 NVYSLSVDPNTWQTLLHER-----------HLRQPEHKVLQQLRSRGDNVYVVTEVLQTQ 167
           N+Y   V P T   +LH R           + RQ      ++   RG+N++ +T+     
Sbjct: 41  NLYRAQVSP-TASDMLHMRWDEELAAFAKAYARQCVWGHNKERGRRGENLFAITDEGMDV 99

Query: 168 KEVEVTRTHKREGSGRFSLPGATCLQGEGQGHLSQ---KKTVTIPSGSTLAFRVAQLVID 224
                   H+RE    ++L  ATC  G+  GH +Q    KT  I  GS    ++ Q V +
Sbjct: 100 PLAMEEWHHERE---HYNLSAATCSPGQMCGHYTQVVWAKTERIGCGSHFCEKL-QGVEE 155

Query: 225 SDLDVLLFPDKKQRTFQPPA-TGHKRSTSEGA-WPQLPSG 262
           +++++L+        ++PP     KR   EG    Q PSG
Sbjct: 156 TNIELLVC------NYEPPGNVKGKRPYQEGTPCSQCPSG 189


>gi|229892328 IQ motif containing C isoform 1 [Homo sapiens]
          Length = 546

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 16/80 (20%)

Query: 227 LDVLLFPDKKQRTFQP----PATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVPAEGA 282
           L++   P++ + ++ P    PA  H   T     P   +G S+  C+  FL         
Sbjct: 54  LEIPAVPNRAEESWDPRTPCPARPHSHHTLA---PDQGNGKSLKACVRGFLV-------- 102

Query: 283 FTEDFQGLRAEVETISKELE 302
               FQ LRAE E I +E+E
Sbjct: 103 -RRQFQSLRAEYEAIVREVE 121


>gi|238908495 similar to pleckstrin homology domain protein (5V327)
           [Homo sapiens]
          Length = 506

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 43/150 (28%), Positives = 61/150 (40%), Gaps = 18/150 (12%)

Query: 283 FTEDFQGLRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPV 342
           F E  Q LR E E I +ELEL  R  C      L+GV +++  LR L E+L+Q      +
Sbjct: 201 FEEVVQELRMEQEQIKRELELTAR--C------LKGVEQEKKELRHLTESLQQ-----TL 247

Query: 343 EPLDGPAGAVLECLVLSSGML-----VPELAIPVVYLLGALTMLSETQHKLLAEALESQT 397
           E L       LE L  +   L       E   P   L   L  + E   +LL E L ++ 
Sbjct: 248 EELSIEKKKTLEMLEENENHLQTLANQSEQPPPSGGLHSNLRQIEEKMQQLLEEKLLAEK 307

Query: 398 LLGPLELVGSLLEQSAPWQERSTMSLPPGL 427
            +   E     LE+   +    + +L   L
Sbjct: 308 RMKENEERSRALEEEREFYSSQSQALQNSL 337


>gi|239753475 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 721

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 66  EPDAAEPDVQRGRSFHFYDAMDGQIQGSVE--LAAPGQAKIAGGAAVSDSSSTSMNVYSL 123
           EP+ + P  +   +F FYD    Q           PG +K++G   V+ ++ST    + +
Sbjct: 527 EPNGSTPSSRALPAFGFYDKSQRQATSPTGGYRRGPGLSKVSGAQDVTRATSTPSRTFDV 586

Query: 124 SVD 126
           SVD
Sbjct: 587 SVD 589


>gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo
           sapiens]
          Length = 721

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 66  EPDAAEPDVQRGRSFHFYDAMDGQIQGSVE--LAAPGQAKIAGGAAVSDSSSTSMNVYSL 123
           EP+ + P  +   +F FYD    Q           PG +K++G   V+ ++ST    + +
Sbjct: 527 EPNGSTPSSRALPAFGFYDKSQRQATSPTGGYRRGPGLSKVSGAQDVTRATSTPSRTFDV 586

Query: 124 SVD 126
           SVD
Sbjct: 587 SVD 589


>gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo
           sapiens]
          Length = 721

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 18/63 (28%), Positives = 30/63 (47%), Gaps = 2/63 (3%)

Query: 66  EPDAAEPDVQRGRSFHFYDAMDGQIQGSVE--LAAPGQAKIAGGAAVSDSSSTSMNVYSL 123
           EP+ + P  +   +F FYD    Q           PG +K++G   V+ ++ST    + +
Sbjct: 527 EPNGSTPSSRALPAFGFYDKSQRQATSPTGGYRRGPGLSKVSGAQDVTRATSTPSRTFDV 586

Query: 124 SVD 126
           SVD
Sbjct: 587 SVD 589


>gi|75677365 dynein heavy chain domain 3 [Homo sapiens]
          Length = 4427

 Score = 31.6 bits (70), Expect = 1.7
 Identities = 16/55 (29%), Positives = 30/55 (54%)

Query: 292 AEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLD 346
           AE   +  E+ + D+EL Q L   +    R    + + +E +E G++LGP+E ++
Sbjct: 225 AEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIE 279


>gi|7705638 bolA-like 1 [Homo sapiens]
          Length = 137

 Score = 31.2 bits (69), Expect = 2.2
 Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 10/110 (9%)

Query: 338 SLGPVEPL------DGPAGAVLECLVLSSGMLVP---ELAIPVVYLLGALTMLSETQHKL 388
           ++GPVE        +  +  VLE    S G  VP   E    V  +      LS  Q   
Sbjct: 28  AIGPVEAAIRTKLEEALSPEVLELRNESGGHAVPPGSETHFRVAVVSSRFEGLSPLQRHR 87

Query: 389 LAEALESQTLLGPLELVGSLLEQSAPWQERSTM-SLPPGLLGNSWGEGAP 437
           L  A  ++ L GP+  +       A W+E S + + PP L GN    G P
Sbjct: 88  LVHAALAEELGGPVHALAIQARTPAQWRENSQLDTSPPCLGGNKKTLGTP 137


>gi|109715835 HEAT repeat containing 6 [Homo sapiens]
          Length = 1181

 Score = 30.4 bits (67), Expect = 3.8
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 7/81 (8%)

Query: 385 QHKLLAEALESQTLLG-------PLELVGSLLEQSAPWQERSTMSLPPGLLGNSWGEGAP 437
           +HK +   + S TLLG       PL  V  LL+Q       ++ S  P L    W + AP
Sbjct: 572 RHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAP 631

Query: 438 AWVLLDECGLELGEDTPHVCW 458
           A   L+E  +   + +   CW
Sbjct: 632 AGPSLEETSVSSPKGSSEPCW 652


>gi|34452725 polypeptide N-acetylgalactosaminyltransferase 4 [Homo
           sapiens]
          Length = 578

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 24/74 (32%), Positives = 35/74 (47%), Gaps = 8/74 (10%)

Query: 130 WQTLLHERH--LRQPEHKVLQQL---RSRGDNVYVVTEV---LQTQKEVEVTRTHKREGS 181
           W TLL   H  L      +L+++       D VY+ T++   +     V + RT+KREG 
Sbjct: 148 WSTLLRTIHSVLETSPAVLLKEIILVDDLSDRVYLKTQLETYISNLDRVRLIRTNKREGL 207

Query: 182 GRFSLPGATCLQGE 195
            R  L GAT   G+
Sbjct: 208 VRARLIGATFATGD 221


>gi|73695473 roquin [Homo sapiens]
          Length = 1133

 Score = 30.0 bits (66), Expect = 4.9
 Identities = 18/54 (33%), Positives = 29/54 (53%)

Query: 277 VPAEGAFTEDFQGLRAEVETISKELELLDRELCQLLLEGLEGVLRDQLALRALE 330
           +P++G F+E  +   +EV +  K L   +RE  +L L+ L   +  Q  LR LE
Sbjct: 934 IPSQGHFSERERISMSEVASHGKPLPSAEREQLRLELQQLNHQISQQTQLRGLE 987


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 12/94 (12%)

Query: 342 VEPLDGPAGAVLECL------VLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALES 395
           +EP++GPA  VL  L        +  +LV +  + +V  L  L+  S+T+ +  AE +  
Sbjct: 438 IEPMEGPAPPVLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPE 497

Query: 396 QTLLGPLELVGSLLEQSA-----PWQERSTMSLP 424
           +++L PL    +L + SA     P  +RS   LP
Sbjct: 498 ESVL-PLVQKSTLADYSAQKDLEPESDRSAQPLP 530


>gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]
          Length = 1016

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 51/197 (25%), Positives = 77/197 (39%), Gaps = 39/197 (19%)

Query: 295 ETISKELELLDRELCQLLLEGLEGVLR----DQLALRALEEALEQ---------GQSLGP 341
           E + ++LE   +E C + L GL+G  R    D+  LRA+E+ L           G ++G 
Sbjct: 288 EELLRQLEQRLQESCSVCLAGLDGFRRQQQEDRERLRAMEKLLASVEERQRHLAGLAVGR 347

Query: 342 VEPLDGPAGAVLECLVLSSGMLVPELAIPVVYLLGALTMLSETQHKLLAEALESQTLLGP 401
             P         EC     G  + EL   +  + G++T+LS  +   L  A       G 
Sbjct: 348 RPP--------QECCSPELGRRLAELERRLDVVAGSVTVLSGRRGTELGGAAGQG---GH 396

Query: 402 LELVGSLLEQSAPWQERSTMSLPPGLLGNSWGEGAPAWVLLDECGLELGEDTPHVCWEPQ 461
                SL  + +  ++R   +L P         GAP        GL          W P 
Sbjct: 397 PPGYTSLASRLSRLEDRFNSTLGPSEEQEESWPGAPG-------GLS--------HWLPA 441

Query: 462 AQGRMCALYASLALLSG 478
           A+GR+  L   LA +SG
Sbjct: 442 ARGRLEQLGGLLANVSG 458


>gi|66392157 RGD motif, leucine rich repeats, tropomodulin domain
           and proline-rich containing [Homo sapiens]
          Length = 1435

 Score = 29.6 bits (65), Expect = 6.4
 Identities = 21/95 (22%), Positives = 44/95 (46%), Gaps = 7/95 (7%)

Query: 185 SLPGATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVID-SDLDVLLFPDKKQRTFQPP 243
           +L G +  + +    L+Q+ TVT+P            +++  +L+ L FP++K+   +  
Sbjct: 881 ALAGLSAARDQLVESLAQQATVTMPPALPAPDGGEPSLLEPGELEGLFFPEEKEEEKE-- 938

Query: 244 ATGHKRSTSEGAWPQLPSGLSMMRCLHNFLTDGVP 278
               K  +    WP+L  GL ++  +H+   +  P
Sbjct: 939 ----KDDSPPQKWPELSHGLHLVPFIHSAAEEAEP 969


>gi|187608767 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 40/125 (32%), Positives = 48/125 (38%), Gaps = 14/125 (11%)

Query: 311 LLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGMLVPELAIP 370
           L+L GL  +L    A R    A       GP  P   P G V+   + +SG      A P
Sbjct: 481 LILSGLPQLLAG--ANRPTNPAPPTVTGAGPAGPSSQPPGTVIAAFIRTSG----TTAAP 534

Query: 371 VVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSA-----PWQERSTMSLPP 425
            V   G L   S  Q  +    +E   LL P E +  LL   A     P Q  S  S  P
Sbjct: 535 RV-KEGPLRSSSYVQGMVTGAPMEG--LLVPEETLRELLRDQAHLQPLPTQVVSRGSHNP 591

Query: 426 GLLGN 430
            LLGN
Sbjct: 592 SLLGN 596


>gi|4503555 E74-like factor 4 [Homo sapiens]
          Length = 663

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 40/125 (32%), Positives = 48/125 (38%), Gaps = 14/125 (11%)

Query: 311 LLLEGLEGVLRDQLALRALEEALEQGQSLGPVEPLDGPAGAVLECLVLSSGMLVPELAIP 370
           L+L GL  +L    A R    A       GP  P   P G V+   + +SG      A P
Sbjct: 481 LILSGLPQLLAG--ANRPTNPAPPTVTGAGPAGPSSQPPGTVIAAFIRTSG----TTAAP 534

Query: 371 VVYLLGALTMLSETQHKLLAEALESQTLLGPLELVGSLLEQSA-----PWQERSTMSLPP 425
            V   G L   S  Q  +    +E   LL P E +  LL   A     P Q  S  S  P
Sbjct: 535 RV-KEGPLRSSSYVQGMVTGAPMEG--LLVPEETLRELLRDQAHLQPLPTQVVSRGSHNP 591

Query: 426 GLLGN 430
            LLGN
Sbjct: 592 SLLGN 596


>gi|47086907 lysophosphatidylcholine acyltransferase 2 [Homo
           sapiens]
          Length = 544

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 16/101 (15%)

Query: 188 GATCLQGEGQGHLSQKKTVTIPSGSTLAFRVAQLVIDSDLDVLLFPDKKQRTFQPPATGH 247
           G  C+       +S+ +   +P    L  R  Q V+ S +D    PD ++ T        
Sbjct: 152 GIACVVAGLPSMVSRNENAQVPLIGRL-LRAVQPVLVSRVD----PDSRKNTINEII--- 203

Query: 248 KRSTSEGAWPQL---PSGLSMMR-CLHNF----LTDGVPAE 280
           KR+TS G WPQ+   P G    R CL  F       GVP +
Sbjct: 204 KRTTSGGEWPQILVFPEGTCTNRSCLITFKPGAFIPGVPVQ 244


>gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]
          Length = 1113

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 10/128 (7%)

Query: 85  AMDGQIQGSVELAAPGQAKIAGGAAVSDS--SSTSMNVYSLSVDPNTWQTLLHERHLRQP 142
           ++   +Q     ++PG    + G+ V+ S  SSTS +   L  DP        E+   + 
Sbjct: 425 SLSSSMQSLSSGSSPGSLTSSRGSLVASSLDSSTSASFTDLYYDP-------FEQLDSEL 477

Query: 143 EHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREGSGRFSLPGATCLQGEGQGHLSQ 202
           + KV + L   G   +  +  + T  E EV +T K EG GR     +     +    LS 
Sbjct: 478 QSKV-EFLLLEGATGFRPSGCITTIHEDEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSP 536

Query: 203 KKTVTIPS 210
           + +++ PS
Sbjct: 537 RSSLSSPS 544


>gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]
          Length = 1118

 Score = 29.3 bits (64), Expect = 8.4
 Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 10/128 (7%)

Query: 85  AMDGQIQGSVELAAPGQAKIAGGAAVSDS--SSTSMNVYSLSVDPNTWQTLLHERHLRQP 142
           ++   +Q     ++PG    + G+ V+ S  SSTS +   L  DP        E+   + 
Sbjct: 425 SLSSSMQSLSSGSSPGSLTSSRGSLVASSLDSSTSASFTDLYYDP-------FEQLDSEL 477

Query: 143 EHKVLQQLRSRGDNVYVVTEVLQTQKEVEVTRTHKREGSGRFSLPGATCLQGEGQGHLSQ 202
           + KV + L   G   +  +  + T  E EV +T K EG GR     +     +    LS 
Sbjct: 478 QSKV-EFLLLEGATGFRPSGCITTIHEDEVAKTQKAEGGGRLQALRSLSGTPKSMTSLSP 536

Query: 203 KKTVTIPS 210
           + +++ PS
Sbjct: 537 RSSLSSPS 544


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,749,170
Number of Sequences: 37866
Number of extensions: 937539
Number of successful extensions: 2685
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 10
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2653
Number of HSP's gapped (non-prelim): 41
length of query: 484
length of database: 18,247,518
effective HSP length: 106
effective length of query: 378
effective length of database: 14,233,722
effective search space: 5380346916
effective search space used: 5380346916
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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