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Search of human proteins with 82775371
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
(631 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82775371 coiled-coil domain containing 93 [Homo sapiens] 1228 0.0
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 68 2e-11
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 67 4e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 67 4e-11
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 65 1e-10
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 65 2e-10
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 64 3e-10
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 64 3e-10
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 64 3e-10
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 64 3e-10
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 64 3e-10
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 64 3e-10
gi|4885583 Rho-associated, coiled-coil containing protein kinase... 64 6e-10
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 62 2e-09
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 61 4e-09
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 61 4e-09
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 61 4e-09
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 61 4e-09
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 61 4e-09
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 60 5e-09
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 60 6e-09
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 60 6e-09
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 60 6e-09
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 60 6e-09
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 60 6e-09
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 60 6e-09
gi|31982906 cingulin-like 1 [Homo sapiens] 60 8e-09
gi|50658069 phosphodiesterase 4D interacting protein isoform 2 [... 59 1e-08
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 59 1e-08
gi|71061468 centromere protein E [Homo sapiens] 59 1e-08
>gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
Length = 631
Score = 1228 bits (3176), Expect = 0.0
Identities = 631/631 (100%), Positives = 631/631 (100%)
Query: 1 MGLPRGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWC 60
MGLPRGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWC
Sbjct: 1 MGLPRGPEGQGLPEVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWC 60
Query: 61 ITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVV 120
ITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVV
Sbjct: 61 ITTCNFDVDVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVV 120
Query: 121 QWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRR 180
QWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRR
Sbjct: 121 QWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRR 180
Query: 181 KYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAH 240
KYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAH
Sbjct: 181 KYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAH 240
Query: 241 EEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSEL 300
EEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSEL
Sbjct: 241 EEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSEL 300
Query: 301 SAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTY 360
SAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTY
Sbjct: 301 SAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTY 360
Query: 361 SEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
SEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN
Sbjct: 361 SEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAI 480
LKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAI
Sbjct: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAI 480
Query: 481 LHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN 540
LHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN
Sbjct: 481 LHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN 540
Query: 541 SIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLE 600
SIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLE
Sbjct: 541 SIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLE 600
Query: 601 KQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS 631
KQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS
Sbjct: 601 KQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS 631
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 68.2 bits (165), Expect = 2e-11
Identities = 94/496 (18%), Positives = 218/496 (43%), Gaps = 72/496 (14%)
Query: 154 EDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSR 213
+D DF +K K +L ++ K +R++ + +ES + LL+ ++
Sbjct: 1529 KDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEV---LLQ-------AK 1578
Query: 214 QSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTAS 273
++++EK + + T+ ++ ++ H+++EL + +Q+ A+ E+ +T
Sbjct: 1579 RAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEK 1638
Query: 274 SVGQIVGLCS--AEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTK 331
C+ E+K ++ E + ++ EL+ + S K Q T
Sbjct: 1639 --------CNHIREVKSLLEELSFQKGELNVQISERK------------------TQLTL 1672
Query: 332 HLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVA 391
+E+ +LQ + K TELK + L E L+ ++ + D + + + VA
Sbjct: 1673 IKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVA 1732
Query: 392 M------NENLKSQEQEFKAHC---REEMTRLQQEIENLKAE-RAPRGDEKTLSSGEPPG 441
+ ENL+ Q+ K ++ + R ++EIE + AE RA + + LS
Sbjct: 1733 VLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSK----- 1787
Query: 442 TLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEV-----PSRAELIQ 496
EDL + ++ ++KL + + + A + ++++ + EL Q
Sbjct: 1788 -------EKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQ 1840
Query: 497 YQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNS--IHENFSQ-AMASP 553
+ + L+ ISA+ ++ ++ N+L ++ ++ ++L +H Q + S
Sbjct: 1841 LNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSE 1900
Query: 554 AARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFK 613
R Q + + + + + + E K+Q+ ++ ++++ + L+L++++ ++ + KE
Sbjct: 1901 QTRLQ--KDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKE-- 1956
Query: 614 EEGRKNEMLLSKVKAK 629
E ++++ SKV K
Sbjct: 1957 RESEESKLETSKVTLK 1972
Score = 46.2 bits (108), Expect = 9e-05
Identities = 98/478 (20%), Positives = 183/478 (38%), Gaps = 85/478 (17%)
Query: 160 KRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEK 219
KR+E+ ++ SE + + H ++LL E+ + + E R RQ + +
Sbjct: 1339 KREERWMRASKRQSE----KEMEELHHNIDDLLQEKKSLECEVEELHRTVQ-KRQQQKDF 1393
Query: 220 AEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIV 279
+ +L L EK+ H ED + E + I+ + K + E RL A
Sbjct: 1394 IDGNVESLMTELEI-EKSLKHHEDIVD--EIECIEKTLLKRRSELREADRLLA------- 1443
Query: 280 GLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRAS 339
E +SELS + K K + + Q EEL
Sbjct: 1444 ---------------EAESELSCTKEKTKNAVE-----KFTDAKRSLLQTESDAEELERR 1483
Query: 340 HTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQ 399
+A + L L+ ++ L++ + E+I L+ + +VA ++
Sbjct: 1484 AQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEI--------LKEINKIVAAKDSDFQC 1535
Query: 400 EQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEP------------PGTLTSAM 447
+ K EE+ +LQ++IE AER + L E +TS
Sbjct: 1536 LSKKKEKLTEELQKLQKDIE--MAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQ 1593
Query: 448 THDEDLDRRYNMEKEKLY---------KIRLLQARRNREIAILHR--KIDEVPSRAELIQ 496
LDR+ +KE+L+ K L +A R E + + I EV S E +
Sbjct: 1594 QEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELS 1653
Query: 497 YQKRFIELYRQIS-----------AVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHEN 545
+QK EL QIS + KE + + + K L+ ++L+ +
Sbjct: 1654 FQKG--ELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELK---NILDMLQLE 1708
Query: 546 FSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQR 603
+ DQ + ++E+ + + ++++E +Q ++ ++ ++ Q +LLE+ +
Sbjct: 1709 NHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQ-KQLLERDK 1765
Score = 40.4 bits (93), Expect = 0.005
Identities = 81/396 (20%), Positives = 169/396 (42%), Gaps = 67/396 (16%)
Query: 221 EDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMT-KMTAMANEESRLTASSVGQIV 279
EDK+ + A + T ++ H DE+ AE+Q +++ K A + +++ + +
Sbjct: 440 EDKEKKISA--AQTRLSELH--DEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLY 495
Query: 280 GLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRAS 339
S + Q+V++ ++ +L + +K ++IA K K +++L+ +
Sbjct: 496 KQLSGRL-QLVNKLRQEALDLELQMEKQK---------------QEIAGKQKEIKDLQIA 539
Query: 340 HTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQ 399
SL ++ + + ++LD +++ES+ D + L + E +K
Sbjct: 540 IDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLD----EILSRIAKETEEIKDL 595
Query: 400 EQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSG--EPPGTLTSAMTHDEDLDRRY 457
E E++T Q + A A + D + + SG E GT+ T ++ R+
Sbjct: 596 E--------EQLTEGQ-----IAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKL 642
Query: 458 NMEKEKLYKIRLLQARRNR-EIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETK 516
EKE L + RL + + R ++ I+ +D R EL + + E + +++A ++T+
Sbjct: 643 RDEKETLLQ-RLTEVEQERDQLEIV--AMDAENMRKELAELESALQEQH-EVNASLQQTQ 698
Query: 517 QFFTLY--------NTLDDKKVYLEKEI-----------SLLNSIHENFSQAMASPAARD 557
+ Y N D + L++E+ S L + E QA+ + +
Sbjct: 699 GDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKA 758
Query: 558 QFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLND 593
QF + EQ + K++ + +N + + QL D
Sbjct: 759 QFSEEKEQ---ENSELHAKLKHLQDDNNLLKQQLKD 791
Score = 39.3 bits (90), Expect = 0.011
Identities = 72/342 (21%), Positives = 133/342 (38%), Gaps = 81/342 (23%)
Query: 331 KHLEELRASHTSLQARYNEAKK-TLTELKTYSEKLDKEQAALEKIESKADPSILQNLRAL 389
+ LE L + Q R ++ +L E++ L+K+ E+++SK L+ ++
Sbjct: 245 RSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSK-QTRFLEEIKNQ 303
Query: 390 VAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTH 449
+N++LK + K C E + L + E LK +KT+ LT A
Sbjct: 304 DKLNKSLKEEAMLQKQSCEELKSDLNTKNELLK--------QKTIE-------LTRAC-- 346
Query: 450 DEDLDRRYNMEKE-KLYKIRLLQARRN---REIAILHRKIDEVP---------------- 489
++Y +E+E YKI N E A + + DE P
Sbjct: 347 ----QKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATES 402
Query: 490 ---SRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENF 546
A+ +Q +K +E Q+ H + L L+DK+ + + L+ +H+
Sbjct: 403 YIIDSAQAVQIKK--MEPDEQLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEI 460
Query: 547 SQA---------------------MASPAARDQFLRQME---QIVEGIKQS----RMKME 578
+A S A +D +Q+ Q+V ++Q ++ME
Sbjct: 461 EKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQME 520
Query: 579 KKKQENKMRRDQLND-----QYLELLEKQRLYFKTVKEFKEE 615
K+KQE ++ ++ D L+ + + + K K KE+
Sbjct: 521 KQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQ 562
Score = 34.7 bits (78), Expect = 0.27
Identities = 92/481 (19%), Positives = 197/481 (40%), Gaps = 70/481 (14%)
Query: 160 KRKE-KAIKTVVDLSEVYKPRRKYKRHQ--GAEELLDEESRIHATLLEYGRRYGFSRQSK 216
K+KE K ++ +D + P+ + + Q G E+ LD ++ + L E SR +K
Sbjct: 529 KQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQL-ESRLDEILSRIAK 587
Query: 217 -MEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSV 275
E+ +D + L G A +A + + + + ++ + ++ + T NE +L
Sbjct: 588 ETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKE 647
Query: 276 GQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEE 335
+ L E ++ E +E +E E S L + ++ + Q Q +
Sbjct: 648 TLLQRLTEVEQERDQLEIVAMDAENMRKELAEL--ESALQEQHEVNASLQQTQG-----D 700
Query: 336 LRASHTSLQARYNEAKKTLTELKTYSEKLDK----EQAALEKIESKADPSILQNLRALVA 391
L A L+AR N +LK EK+ + EQ+AL+ E + + L+N
Sbjct: 701 LSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQA-ELEKERQALKNALGKAQ 759
Query: 392 MNENLKSQEQEFKA---HCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMT 448
+E + + E A H +++ L+Q++++ + + +
Sbjct: 760 FSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHL---------------NHVVDGLV 804
Query: 449 HDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQI 508
E++ R + + KL +L N +H D + L QK+F E+ +
Sbjct: 805 RPEEVAARVDELRRKL---KLGTGEMN-----IHSPSDVLGK--SLADLQKQFSEILARS 854
Query: 509 SAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVE 568
E + + ++K L++E++L Q +++F + E+ +E
Sbjct: 855 KWERDEAQ--------VRERK--LQEEMAL---------QQEKLATGQEEFRQACERALE 895
Query: 569 GIKQSRMKMEKKKQENKMRRDQLNDQYLE--LLEKQRLYFKTVKEFKEEGRKNEMLLSKV 626
+RM +K++ E ++++ + YL+ L + + T + +E + E +L+++
Sbjct: 896 ----ARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQL 951
Query: 627 K 627
+
Sbjct: 952 R 952
Score = 33.1 bits (74), Expect = 0.80
Identities = 80/412 (19%), Positives = 170/412 (41%), Gaps = 76/412 (18%)
Query: 80 IGQKIALSEKIVSVLPRMKCPH-----------QLEPHQIQGMDFIHIFPVVQWLVKRAI 128
I Q+I E+ + V+ R H QLE H++QG+ H V + L K +
Sbjct: 1673 IKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSE-LEKTQV 1731
Query: 129 ETKEEMGDYIRSYSVSQFQK------TYSLPEDDDFIKR---KEKAIKTVVDLSEVYKP- 178
EE + +SQ QK L D I+R + +A+++ V+ K
Sbjct: 1732 AVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKED 1791
Query: 179 --------RRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAG 230
+K + + +E S++ + LE Q ++++ K +L
Sbjct: 1792 LQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHND 1851
Query: 231 LSAT-----EKADA---------HEEDELRAAEEQRIQS------LMTKMTAMAN----- 265
+SA EK +A + +D L A++ + + L+++ T +
Sbjct: 1852 ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEW 1911
Query: 266 ----EESRLTASSVGQIVGLCSAEIKQ----IVSE---YAEKQSELSAEESPEKLGTSQL 314
E+ + + Q + + EI++ +V + + Q E +EES KL TS++
Sbjct: 1912 ANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEES--KLETSKV 1969
Query: 315 H-RRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEK 373
+ + L K++ + L+++ + + + R +TL E + + E L+K + ++
Sbjct: 1970 TLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERV----RTLQEEERWCESLEKTLSQTKR 2025
Query: 374 IESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMT---RLQQEIENLK 422
S+ + +++ L+A+ + S +F + +T + ++++ +LK
Sbjct: 2026 QLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLK 2077
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 67.4 bits (163), Expect = 4e-11
Identities = 93/467 (19%), Positives = 203/467 (43%), Gaps = 53/467 (11%)
Query: 159 IKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEES-----RIH-------ATLLEYG 206
+K E+A+ V++ + + K ++ Q E L +E R+H ++L E
Sbjct: 592 LKAMEEAVAQVLEQDQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLRERL 651
Query: 207 RRYGFSRQSKMEKAEDKKTA-LPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMAN 265
++ +++M + E ++ + L A + ++ +AD ED++RA +E +Q L ++ +
Sbjct: 652 QKAIEEEEARMREEESQRLSWLRAQVQSSTQAD---EDQIRAEQEASLQKLREELESQQK 708
Query: 266 EESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQ 325
E Q++ EI+ A ++SE +A + ++ QL + +
Sbjct: 709 AERASLEQKNRQMLEQLKEEIE------ASEKSEQAALNAAKEKALQQLREQLEGERKEA 762
Query: 326 IAQKTK-HLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQ 384
+A K H EL +SL+A++ E +L K E KE+A L+K + + + Q
Sbjct: 763 VATLEKEHSAELERLCSSLEAKHREVVSSLQ--KKIQEAQQKEEAQLQKCLGQVEHRVHQ 820
Query: 385 NLRALVAMNENLKS----QEQEFKAHCREEMTRLQQEIENLKAE-RAPRGDEKTLSSGEP 439
+ L S + QE + + ++++E + + A+ R E+ E
Sbjct: 821 KSYHVAGYEHELSSLLREKRQEVEGEHERRLDKMKEEHQQVMAKAREQYEAEERKQRAEL 880
Query: 440 PGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKID--------EVPSR 491
G LT +L+R + +L +R Q +R ++ HR+ + ++ +R
Sbjct: 881 LGHLTG------ELERLQRAHERELETVRQEQHKRLEDLRRRHREQERKLQDLELDLETR 934
Query: 492 AELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMA 551
A+ ++ + +E+ Q +E +Q + ++V L+ E + + H+ +A
Sbjct: 935 AKDVKARLALLEV--QEETARREKQQLLDV-----QRQVALKSEEA--TATHQQLEEAQK 985
Query: 552 SPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLEL 598
Q +Q+ +I++ ++ ++K+E + + + QL + L
Sbjct: 986 EHTHLLQSNQQLREILDELQARKLKLESQVDLLQAQSQQLQKHFSSL 1032
Score = 39.7 bits (91), Expect = 0.009
Identities = 99/436 (22%), Positives = 186/436 (42%), Gaps = 85/436 (19%)
Query: 188 AEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEED---- 243
AEEL ++ + + L R S + EK +++ + E+A+ EE
Sbjct: 507 AEELGEDSAASLSLQLSLQREQAPSPPAACEKGKEQHSQAEELGPGQEEAEDPEEKVAVS 566
Query: 244 -------ELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEK 296
E+R+ E +++ A EE+ V Q++ + + E ++
Sbjct: 567 PTPPVSPEVRSTEPVAPPEQLSEAALKAMEEA------VAQVLEQDQRHLLESKQEKMQQ 620
Query: 297 QSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTE 356
E +E E++ +LH++K SL+ + K +EE A + R E+++ L+
Sbjct: 621 LREKLCQEEEEEI--LRLHQQKEQSLSSLRERLQKAIEEEEA-----RMREEESQR-LSW 672
Query: 357 LKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHC----REEMT 412
L+ + QA ++I ++ + S LQ LR E L+SQ++ +A R+ +
Sbjct: 673 LRAQVQS--STQADEDQIRAEQEAS-LQKLR------EELESQQKAERASLEQKNRQMLE 723
Query: 413 RLQQEIE-NLKAERAP--RGDEKTLSS--GEPPGTLTSAMTHDEDLDRRYNMEKEKLYKI 467
+L++EIE + K+E+A EK L + G A+ L++ ++ E E+L
Sbjct: 724 QLKEEIEASEKSEQAALNAAKEKALQQLREQLEGERKEAVA---TLEKEHSAELERLCSS 780
Query: 468 RLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDD 527
L+A+ ++ L +KI E + E Q QK ++ + VH+++ Y+
Sbjct: 781 --LEAKHREVVSSLQKKIQEAQQKEEA-QLQKCLGQVEHR---VHQKS------YHVAG- 827
Query: 528 KKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMR 587
E E+S L LR+ Q VEG + +++K K+E++
Sbjct: 828 ----YEHELSSL--------------------LREKRQEVEG--EHERRLDKMKEEHQQV 861
Query: 588 RDQLNDQYLELLEKQR 603
+ +QY KQR
Sbjct: 862 MAKAREQYEAEERKQR 877
Score = 36.2 bits (82), Expect = 0.094
Identities = 47/235 (20%), Positives = 97/235 (41%), Gaps = 25/235 (10%)
Query: 179 RRKYKRHQGAEEL-LDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKA 237
R K + +G E LD+ H ++ R + + + ++AE L L ++A
Sbjct: 837 REKRQEVEGEHERRLDKMKEEHQQVMAKAREQ-YEAEERKQRAE-LLGHLTGELERLQRA 894
Query: 238 DAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQ 297
E + +R + +R++ L + + L +++ + +
Sbjct: 895 HERELETVRQEQHKRLEDLRRRHREQERKLQDL------------ELDLETRAKDVKARL 942
Query: 298 SELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTEL 357
+ L +E T++ +++++ + +Q+A K+ EE A+H L+ E L
Sbjct: 943 ALLEVQEE-----TARREKQQLLDVQRQVALKS---EEATATHQQLEEAQKEHTHLLQSN 994
Query: 358 KTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMT 412
+ E LD+ QA K+ES+ D +LQ + + + E + K H E+T
Sbjct: 995 QQLREILDELQARKLKLESQVD--LLQAQSQQLQKHFSSLEAEAQKKQHLLREVT 1047
Score = 33.1 bits (74), Expect = 0.80
Identities = 52/188 (27%), Positives = 88/188 (46%), Gaps = 21/188 (11%)
Query: 454 DRRYNME--KEKLYKIR-LLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISA 510
D+R+ +E +EK+ ++R L EI LH++ ++ S + L + ++ IE + +
Sbjct: 606 DQRHLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQ--SLSSLRERLQKAIE--EEEAR 661
Query: 511 VHKETKQFFTLYNT-------LDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQM 563
+ +E Q + D+ ++ E+E SL E SQ A A+ +Q RQM
Sbjct: 662 MREEESQRLSWLRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQM 721
Query: 564 -EQIVEGIKQSRMKMEKKKQEN-KMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEM 621
EQ+ E I+ S EK +Q +++ Q E LE +R E KE + E
Sbjct: 722 LEQLKEEIEAS----EKSEQAALNAAKEKALQQLREQLEGERKEAVATLE-KEHSAELER 776
Query: 622 LLSKVKAK 629
L S ++AK
Sbjct: 777 LCSSLEAK 784
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 67.4 bits (163), Expect = 4e-11
Identities = 129/597 (21%), Positives = 250/597 (41%), Gaps = 96/597 (16%)
Query: 69 DVDLLFQENSTIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAI 128
D+++ Q + ++ +K A + KC Q+Q + F V L K I
Sbjct: 1378 DLNVQLQNSISLSEKEAAISSLRKQYDEEKCELL---DQVQDLSF-----KVDTLSKEKI 1429
Query: 129 ETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQGA 188
E++ D+ +S + + + + +K E I+ + E Y+ K ++
Sbjct: 1430 SALEQVDDWSNKFSEWKKKAQSRFTQHQNTVK--ELQIQLELKSKEAYE---KDEQINLL 1484
Query: 189 EELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAA 248
+E LD++++ L K E +DK S EK +++ E EL++
Sbjct: 1485 KEELDQQNKRFDCL-------------KGEMEDDK--------SKMEKKESNLETELKS- 1522
Query: 249 EEQRIQSLMTKMTAMANEESRLTA--SSVGQIVGLCSAEIKQIVSEYAE--KQSELSAEE 304
+ RI L +T E L + Q + E+ Q + + E ++ + +E
Sbjct: 1523 QTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKE 1582
Query: 305 SPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKL 364
+ EK+ T + +V S+ ++ K K LE H +L + E ELK ++L
Sbjct: 1583 AEEKILTLE---NQVYSMKAELETKKKELE-----HVNLSVKSKEE-----ELKALEDRL 1629
Query: 365 DKEQAA-LEKIESKADPSILQNLRALVAMNENLKSQEQE-FKAHCREEMTRLQQEIENLK 422
+ E AA L +++ KA+ I + L++ E + Q ++ ++H E T+LQ+
Sbjct: 1630 ESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQER----- 1684
Query: 423 AERAPRGDEKTLSSGEPPGTLT----------SAMTHDEDLDRRYNMEKEKLYKIRLLQA 472
ER E+ L S E + T +A T E+ D + ++K KI +LQ
Sbjct: 1685 -EREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR 1743
Query: 473 RRNREIAILHR----KIDEVPSRAEL-IQYQKRFIELYRQISAVHKETKQFFTLYNTLDD 527
+ +L R K + V S E+ QYQ+R I+L + H++ L L++
Sbjct: 1744 NLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEE 1803
Query: 528 KK--------VYLEKE-----ISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSR 574
K ++EKE I ++ F + ++ + +EQ IK+
Sbjct: 1804 KNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQ---KIKELD 1860
Query: 575 MKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKT-----VKEFKEEGRKNEMLLSKV 626
+ ++K+ +++ ++L +Y +L Q++ + ++E EE K+ ++ K+
Sbjct: 1861 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL 1917
Score = 58.9 bits (141), Expect = 1e-08
Identities = 111/536 (20%), Positives = 220/536 (41%), Gaps = 67/536 (12%)
Query: 145 QFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLE 204
+ +K S + + +RK KA ++ E K K + L E SR+ +++
Sbjct: 415 ELEKALSTAQKTEEARRKLKA-----EMDEQIKTIEKTSEEERIS-LQQELSRVKQEVVD 468
Query: 205 YGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHE---EDELRAAEEQ------RIQS 255
++ + +K++K +K+ A T+K E +++++ A E+ +I
Sbjct: 469 VMKKSSEEQIAKLQKLHEKELARKEQ-ELTKKLQTREREFQEQMKVALEKSQSEYLKISQ 527
Query: 256 LMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLH 315
+ ++A EE L ++ +++Q Y + EL E S EK +
Sbjct: 528 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL--ESSLEKSLQENKN 585
Query: 316 RRKVISL---------NKQIAQKT-KHLEELRASHTSLQARYNEAKKTL-----TELKTY 360
+ K +++ NK+I KH EL + A + E + L TE++
Sbjct: 586 QSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKL 645
Query: 361 SEKLDKEQAALEKIES--------KADPSILQNLRALVAMNENLKSQEQEF---KAHCRE 409
EK ++E+ L K + + + L+ L E+L S+ E + E
Sbjct: 646 REKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 705
Query: 410 EMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRL 469
E++ L+ + + +K E + DE+ + ++ H+ + R K+++ ++ L
Sbjct: 706 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKE--HEVSIQRTEKALKDQINQLEL 763
Query: 470 LQARRNREIA-----ILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNT 524
L R++ + + + + D S EL Q + SA H++TK +
Sbjct: 764 LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQ 823
Query: 525 LDDKKVYLEKE-ISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKK-KQ 582
L K + LE E I L + E +Q D Q++ +++ +++ +ME+K K
Sbjct: 824 LQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKS 883
Query: 583 ENKMRRDQLNDQYLE-------LLEKQRLYFKTVKEFKEEGRKN--EMLLSKVKAK 629
++ +L D E L+EK+ + + EG+K E+L K+ AK
Sbjct: 884 LTQVYESKLEDGNKEQEQTKQILVEKENMILQ-----MREGQKKEIEILTQKLSAK 934
Score = 52.4 bits (124), Expect = 1e-06
Identities = 119/582 (20%), Positives = 235/582 (40%), Gaps = 84/582 (14%)
Query: 82 QKIALSEKIVSVLPRMK--CPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIR 139
++I L++++ V + K C +L+ H+IQ D ++Q L K+ E ++++ +
Sbjct: 834 ERILLTKQVAEVEAQKKDVCT-ELDAHKIQVQD------LMQQLEKQNSEMEQKVKSLTQ 886
Query: 140 SYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQG---AEELLDEES 196
Y S ED + K +E+ + +V+ + R+ ++ + ++L +E
Sbjct: 887 VYE--------SKLEDGN--KEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKED 936
Query: 197 RIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSAT---EKADAHEEDELRAAE-EQR 252
IH EY ++ +++ KMEK + K + L ++A +E E A E Q+
Sbjct: 937 SIHILNEEYETKFK-NQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQK 995
Query: 253 IQSLMTKMTAMANEES--------RLTASSVGQIVGLCSA---EIKQIVS-------EYA 294
+ KM MA S RL + QI L E+ ++S + A
Sbjct: 996 EKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQA 1055
Query: 295 EKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTL 354
E+ E+ + EK ++K++ + + K + L+ NE ++ L
Sbjct: 1056 EELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQL 1115
Query: 355 TELKTYSEKLDKEQ----AALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREE 410
+ + L +++ A LEK+E + S+ +N + E LK +E K E
Sbjct: 1116 KQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVE-LKMLAEEDKRKVSEL 1174
Query: 411 MTRLQ---QEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKI 467
++L+ +E ++LK+ EK+ S E ++ + + +K +
Sbjct: 1175 TSKLKTTDEEFQSLKSSH-----EKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEA--- 1226
Query: 468 RLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDD 527
LL+A+ N I I K + + SR Q++ + KE T T+ +
Sbjct: 1227 -LLEAKTNELINISSSKTNAILSRISHCQHRTTKV----------KEALLIKTC--TVSE 1273
Query: 528 KKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMR 587
+ L + N+++ +F QA Q+E+ IK + +E E +
Sbjct: 1274 LEAQLRQLTEEQNTLNISFQQAT----------HQLEEKENQIKSMKADIESLVTEKEAL 1323
Query: 588 RDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVKAK 629
+ + +Q EK+ + KE E ++ ++K K
Sbjct: 1324 QKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK 1365
Score = 51.2 bits (121), Expect = 3e-06
Identities = 72/385 (18%), Positives = 160/385 (41%), Gaps = 44/385 (11%)
Query: 241 EEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSEL 300
E++ L+ ++R+Q L E+++L + K ++ + + + +
Sbjct: 315 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQL---------RDAKNLIEQLEQDKGMV 365
Query: 301 SAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELR--------ASHTSLQARYNEAKK 352
AE + T ++ ++ L +I Q T EELR A+ L+ + A+K
Sbjct: 366 IAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQK 425
Query: 353 TLTELKTYSEKLDKEQAALEKIESKADPSILQNL-----RALVAMNENLKSQEQEFKAHC 407
T + ++D++ +EK + S+ Q L + M ++ + Q + +
Sbjct: 426 TEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLH 485
Query: 408 REEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKI 467
+E+ R +QE+ R E+ + E + ++ +++ +E+ +L K
Sbjct: 486 EKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 545
Query: 468 RLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETK-QFFTLYNTLD 526
+L N K+ ++ AE Y+ R +EL + +E K Q L L+
Sbjct: 546 AILTESEN--------KLRDLQQEAE--TYRTRILELESSLEKSLQENKNQSKDLAVHLE 595
Query: 527 DKKVYLEKEISLLNSIHENFSQAMAS----------PAARDQFLRQMEQIVEGIKQSRMK 576
+K KEI+++ H+ +++ + Q+ +ME++ E +Q +
Sbjct: 596 AEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKET 655
Query: 577 MEKKKQ-ENKMRRDQLNDQYLELLE 600
+ K K+ + +++N++ LE L+
Sbjct: 656 LLKDKEIIFQAHIEEMNEKTLEKLD 680
Score = 50.1 bits (118), Expect = 6e-06
Identities = 113/558 (20%), Positives = 222/558 (39%), Gaps = 65/558 (11%)
Query: 131 KEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSE----------VYKPRR 180
K+E+ D ++ S Q K L E + + RKE+ + + E + K +
Sbjct: 463 KQEVVDVMKKSSEEQIAKLQKLHEKE--LARKEQELTKKLQTREREFQEQMKVALEKSQS 520
Query: 181 KY------KRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSAT 234
+Y K Q + L + E + A L E + Q + E + L + L +
Sbjct: 521 EYLKISQEKEQQESLALEELELQKKAILTESENKLR-DLQQEAETYRTRILELESSLEKS 579
Query: 235 EKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYA 294
+ + ++ +L E ++T M + S Q L + +++ + +Y
Sbjct: 580 LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQ 639
Query: 295 EKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKT-KHLEELRASHTSLQARYNEAKKT 353
+ +L + EK L + K I I + K LE+L T L++ +E +
Sbjct: 640 TEMEKLREKCEQEK---ETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEV 696
Query: 354 LTELKTYSEKL----DKEQAALEKIESKADP----------SILQNLRALVAMNEN-LKS 398
L E+L D+ +++E+K D SI++ + E LK
Sbjct: 697 LKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKD 756
Query: 399 QEQEFKAHCREEMTRL---QQEIENLKAE-RAPRGDEKTLSSGEPPGTLTSAMTHDED-- 452
Q + + +E L Q +ENL+A+ + G+ + S+ + TH++
Sbjct: 757 QINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKA 816
Query: 453 LDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSR--AELIQYQKRFIELYRQISA 510
+ + ++KL + + +++A + + +V + A IQ Q +L +Q S
Sbjct: 817 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSE 876
Query: 511 VHKETKQFFTLYNT-LDD--------KKVYLEKEISLLNSIH------ENFSQAMASPAA 555
+ ++ K +Y + L+D K++ +EKE +L E +Q ++ A
Sbjct: 877 MEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLS--AK 934
Query: 556 RDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYL--ELLEKQRLYFKTVKEFK 613
D E+ K KMEK KQ+ K ++ L + L E K+ L ++ +
Sbjct: 935 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 994
Query: 614 EEGRKNEMLLSKVKAKAS 631
+E + N +L +A ++
Sbjct: 995 KEKQFNAKMLEMAQANSA 1012
Score = 45.8 bits (107), Expect = 1e-04
Identities = 121/575 (21%), Positives = 221/575 (38%), Gaps = 99/575 (17%)
Query: 118 PVVQWLVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYK 177
P+ Q + + TKEE + V +L +KR+E +K + + +K
Sbjct: 247 PLPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHK 306
Query: 178 PR------RKYKRHQGAEELLDEESRIHAT-LLEYGRRYGFSRQSK--MEKAEDKKTALP 228
+ K + +E L E +I + E + R +K +E+ E K +
Sbjct: 307 EQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMV- 365
Query: 229 AGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANE-------------ESRLTASSV 275
A K HE E++ E +++S + +MT E E A S
Sbjct: 366 ---IAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALST 422
Query: 276 GQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNK-----QIAQKT 330
Q ++K + E + + S EE +++V+ + K QIA+
Sbjct: 423 AQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQ 482
Query: 331 K-HLEELRASHTSL-------QARYNEAKKTLTE------LKTYSEKLDKEQAALEKIES 376
K H +EL L + + E K E LK EK +E ALE++E
Sbjct: 483 KLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELE- 541
Query: 377 KADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIE---------------NL 421
LQ L L+ +QE + + R + L+ +E +L
Sbjct: 542 ------LQKKAILTESENKLRDLQQEAETY-RTRILELESSLEKSLQENKNQSKDLAVHL 594
Query: 422 KAERAPRGDEKTLSSGEPPGTLTSAMTHDED---------LDRRYNMEKEKLYKIRLLQA 472
+AE+ E T+ E T ++ H +D L ++Y E EKL + +
Sbjct: 595 EAEKNKHNKEITVMV-EKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLRE----KC 649
Query: 473 RRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYL 532
+ +E + K E+ +A + + ++ +E ++ E + + + + + L
Sbjct: 650 EQEKETLL---KDKEIIFQAHIEEMNEKTLE---KLDVKQTELESLSSELSEVLKARHKL 703
Query: 533 EKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLN 592
E+E+S+L + Q + + +Q +Q+ IK+ + +++ + K +DQ+N
Sbjct: 704 EEELSVLKDQTDKMKQELEA-KMDEQKNHHQQQVDSIIKEHEVSIQRTE---KALKDQIN 759
Query: 593 DQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVK 627
LELL K+R K KE E L + +K
Sbjct: 760 Q--LELLLKER-----DKHLKEHQAHVENLEADIK 787
Score = 37.4 bits (85), Expect = 0.042
Identities = 97/494 (19%), Positives = 189/494 (38%), Gaps = 79/494 (15%)
Query: 160 KRKEKAIKTVVDLSEVYKPRR-------KYKRHQGAEELLDEESRIHATLLEYGR----- 207
K+ EK + ++ E K + K + A EL +E + +A +LE +
Sbjct: 954 KKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAG 1013
Query: 208 ------RYGFSRQSKMEK-AEDKKTALPAGLSATEKADAHEEDELRAA-------EEQRI 253
R +++ ++E E + L +S EK + +EL+ +EQ +
Sbjct: 1014 ISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEV 1073
Query: 254 QSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQ--IVSEYAEKQSELSAEESPEKLGT 311
L K+ E+ + +I L +KQ ++E E+ + SA +
Sbjct: 1074 AELKQKILLFGCEKEEMNK----EITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDE 1129
Query: 312 SQL--HRRKV-ISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ 368
++L H K+ + LNK + + T E+L L+ E K+ ++EL + + D+E
Sbjct: 1130 TKLKAHLEKLEVDLNKSLKENTFLQEQL----VELKMLAEEDKRKVSELTSKLKTTDEEF 1185
Query: 369 AALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPR 428
+L+ K+ N++L+ + EFK E +L + +A +
Sbjct: 1186 QSLKSSHEKS--------------NKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAK 1231
Query: 429 GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEV 488
+E S + S ++H R KE L L++ E+ R++ E
Sbjct: 1232 TNELINISSSKTNAILSRISH---CQHRTTKVKEAL----LIKTCTVSELEAQLRQLTEE 1284
Query: 489 PSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQ 548
+ + F + Q+ + K +L +K L+KE N Q
Sbjct: 1285 QNTLNI-----SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKE-------GGNQQQ 1332
Query: 549 AMA-SPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLND------QYLELLEK 601
A + + Q +++ + + + + ++++KK E QL D + L EK
Sbjct: 1333 AASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEK 1392
Query: 602 QRLYFKTVKEFKEE 615
+ K++ EE
Sbjct: 1393 EAAISSLRKQYDEE 1406
Score = 35.0 bits (79), Expect = 0.21
Identities = 78/447 (17%), Positives = 174/447 (38%), Gaps = 87/447 (19%)
Query: 147 QKTY---------SLPEDDDFIKR----KEKAIKTVVDLSEVYKPRRKYKRHQGAEELLD 193
QKTY +L E + ++R KE+ + + ++ Y+ R H A++ D
Sbjct: 1731 QKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED 1790
Query: 194 EE--SRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQ 251
+ + L E ++Y +EK K + A + + +D + +E+
Sbjct: 1791 QSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNN-----IQAKQNLENVFDDVQKTLQEK 1845
Query: 252 RIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQS--ELSAEESPEKL 309
+ + + + + V ++ E++++ S+Y + Q+ ++ P +L
Sbjct: 1846 ELTCQILEQKIKELDSCLVRQKEVHRV------EMEELTSKYEKLQALQQMDGRNKPTEL 1899
Query: 310 GTSQLHRRKVISLNKQIAQKTK-HLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ 368
L + +K+K HL + + ++++A++N+ + L + +KL KE
Sbjct: 1900 ------------LEENTEEKSKSHLVQPKLL-SNMEAQHNDLEFKLAGAEREKQKLGKEI 1946
Query: 369 AALEK----------------------------------IESKADPSILQNLRALVAMNE 394
L+K +E K + ++ Q +R N
Sbjct: 1947 VRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMR---EFNT 2003
Query: 395 NLKSQEQEFKAHCREEMTRLQQ-EIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDL 453
L +EQE + +E + + Q+ E E L++ + + + +A ++E L
Sbjct: 2004 QLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEIL 2063
Query: 454 DRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPS----RAELIQYQKRFIELYRQIS 509
D R E+E K+R LQ + +K+++ + +++ Q + + IS
Sbjct: 2064 DAR---EEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMELQTQLAQKTTLIS 2120
Query: 510 AVHKETKQFFTLYNTLDDKKVYLEKEI 536
+ ++F + L+D+ EK +
Sbjct: 2121 DSKLKEQEFREQIHNLEDRLKKYEKNV 2147
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 65.5 bits (158), Expect = 1e-10
Identities = 98/473 (20%), Positives = 191/473 (40%), Gaps = 66/473 (13%)
Query: 183 KRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKAD---- 238
K+ + ++LL EE I A E R + K KA AL L A E+ +
Sbjct: 1448 KKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNK 1507
Query: 239 -------------------AHEEDELRAAEEQRIQSLMTKMTAM-----ANEESRLTASS 274
HE ++ + A EQ+++ + T++ + A E+++L
Sbjct: 1508 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1567
Query: 275 VGQIVGLCSAEIKQIVSEYAEKQSELSAEESPE---KLGTSQLHRRKVISLNKQIAQKTK 331
Q + Q E E++ L ++ E +L + R ++ K++ K
Sbjct: 1568 NMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
Query: 332 HLE-ELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKI--ESKADPSILQNLRA 388
LE ++ A++ + + +K ++K Y +L++ +A+ ++I +SK L++L A
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
Query: 389 -LVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAM 447
++ + E L S E+ + H +E L EI N + ++ DEK A
Sbjct: 1688 EILQLQEELASSERA-RRHAEQERDELADEITNSASGKSALLDEKRRLEAR------IAQ 1740
Query: 448 THDEDLDRRYNME--KEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELY 505
+E + + NME ++ K L N E+A + + + ++ Q + EL
Sbjct: 1741 LEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNK--ELK 1798
Query: 506 RQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQ 565
++ + K F K + + + + E Q AA ++ +R+ E+
Sbjct: 1799 AKLQELEGAVKSKF---------KATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEK 1849
Query: 566 IVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRK 618
+K+ M++E +++ DQY E +EK K +K EE +
Sbjct: 1850 ---KLKEIFMQVEDERRHA--------DQYKEQMEKANARMKQLKRQLEEAEE 1891
Score = 61.2 bits (147), Expect = 3e-09
Identities = 95/461 (20%), Positives = 195/461 (42%), Gaps = 42/461 (9%)
Query: 160 KRKEKAIKTVVDLSEVYKPRRKYKRHQ-----GAEELLDEESRIHATLLEYGRRYGFSRQ 214
+++ KA+ L E + + +++R E+L+ + + + E + S++
Sbjct: 1480 EKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK----SKR 1535
Query: 215 SKMEKAEDKKTALPA---GLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLT 271
+ ++ E+ +T L L ATE A E ++A + Q + L T+ E+ RL
Sbjct: 1536 ALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR-DEQNEEKKRLL 1594
Query: 272 ASSVGQIVGLCSAEIKQ-IVSEYAEKQSELSAEESPEKLGTSQLHRRKVIS----LNKQI 326
V ++ E KQ ++ ++K+ E+ ++ ++ + R +VI L Q+
Sbjct: 1595 IKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQM 1654
Query: 327 AQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNL 386
+ LEE RAS + A+ E++K L L+ +L +E A+ E+ A+ L
Sbjct: 1655 KDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQE-RDEL 1713
Query: 387 RALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGD---EKTLS----SGEP 439
+ + + KS + K + +L++E+E ++ D + TL + E
Sbjct: 1714 ADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAEL 1773
Query: 440 PGTLTSAMTHD---EDLDRRYNMEKEKLYKIR-LLQARRNREIAILHRKIDEVPSRAELI 495
++A D + L+R+ K KL ++ ++++ I+ L KI ++ + E
Sbjct: 1774 AAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE-- 1831
Query: 496 QYQKRFIELYRQISAVHKETKQFFTLYNT----LDDKKVYLEKEIS----LLNSIHENFS 547
Q K + + K+ K+ F D K +EK + L + E
Sbjct: 1832 QEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEE 1891
Query: 548 QAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRR 588
+A + A+R + R+++ E + E +N++RR
Sbjct: 1892 EATRANASRRKLQRELDDATEA--NEGLSREVSTLKNRLRR 1930
Score = 53.1 bits (126), Expect = 7e-07
Identities = 77/388 (19%), Positives = 158/388 (40%), Gaps = 35/388 (9%)
Query: 215 SKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASS 274
S++ + E+K L + E + E+ L+ E+ R Q L + E + L
Sbjct: 1013 SQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTR-QELEKAKRKLDGETTDLQ--- 1068
Query: 275 VGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVIS----LNKQIAQKT 330
QI L A+I ++ + A+K+ EL + + LH+ + L QIA+
Sbjct: 1069 -DQIAEL-QAQIDELKLQLAKKEEELQGALA--RGDDETLHKNNALKVVRELQAQIAELQ 1124
Query: 331 KHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALV 390
+ E +AS + + + + L LKT E AA +++ +K + + + +AL
Sbjct: 1125 EDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALE 1184
Query: 391 AMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHD 450
+N ++Q Q+ + + L +++E K +A K G T
Sbjct: 1185 EETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK-------QGLETDNKELA 1237
Query: 451 EDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISA 510
++ ++ E +K + L A ++ LH K+ E + +EL + S
Sbjct: 1238 CEVKVLQQVKAESEHKRKKLDA----QVQELHAKVSE---------GDRLRVELAEKASK 1284
Query: 511 VHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGI 570
+ E TL + K + K+ + L S ++ +Q + R + + + +
Sbjct: 1285 LQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQD-TQELLQEETRQKL--NLSSRIRQL 1341
Query: 571 KQSRMKMEKKKQENKMRRDQLNDQYLEL 598
++ + ++++++E + R L Q L L
Sbjct: 1342 EEEKNSLQEQQEEEEEARKNLEKQVLAL 1369
Score = 52.4 bits (124), Expect = 1e-06
Identities = 78/398 (19%), Positives = 169/398 (42%), Gaps = 39/398 (9%)
Query: 241 EEDELRAAEEQ--RIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQS 298
+E+EL+A +E+ +++ TK+ E R + E K I++E + ++
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLL---------EEKNILAEQLQAET 900
Query: 299 EL--SAEESPEKLGTSQLHRRKVI-SLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLT 355
EL AEE +L + +++ L ++ ++ + + L+ +QA + ++ L
Sbjct: 901 ELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLD 960
Query: 356 ELKTYSEKLDKEQAALEKIESKADPSIL----QNLRALVAMNENLKSQEQEFKAHCREE- 410
E + +KL E+ E K + IL QN + + + ++ + E + EE
Sbjct: 961 EEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSK-FIKEKKLMEDRIAECSSQLAEEE 1019
Query: 411 -------MTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEK 463
R +QE+ E + +EKT E T DL + + +
Sbjct: 1020 EKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGET--TDLQDQIAELQAQ 1077
Query: 464 LYKIRLLQARRNREI-AILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLY 522
+ +++L A++ E+ L R DE + ++ + EL QI+ + ++ +
Sbjct: 1078 IDELKLQLAKKEEELQGALARGDDETLHKNNALKVVR---ELQAQIAELQEDFESEKASR 1134
Query: 523 NTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
N + +K L +E+ L + + + AA+ + + EQ V +K++ +E++ +
Sbjct: 1135 NKAEKQKRDLSEELEALKT---ELEDTLDTTAAQQELRTKREQEVAELKKA---LEEETK 1188
Query: 583 ENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNE 620
++ + + ++ LE+ + K FK KN+
Sbjct: 1189 NHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
Score = 46.6 bits (109), Expect = 7e-05
Identities = 98/490 (20%), Positives = 195/490 (39%), Gaps = 105/490 (21%)
Query: 186 QGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTA----------LPAGLSATE 235
Q +ELL EE+R L R+ + S E+ E+++ A L + L+ T+
Sbjct: 1318 QDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTK 1377
Query: 236 KA--------DAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEI- 286
K ++ EE + + ++ S + A+A ++ T + + Q + + ++
Sbjct: 1378 KKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLD 1437
Query: 287 --KQIVSEYAEKQSELS-------------AEESPEKLGTSQLHRRKVISLNKQIAQKTK 331
+Q+ S +KQ + AEE ++ K +SL + + + +
Sbjct: 1438 HQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALE 1497
Query: 332 HLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVA 391
EE + L+A + + ++ +L+K + ALE + +
Sbjct: 1498 AKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALE--------------QQVEE 1543
Query: 392 MNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDE 451
M L+ E E +A + RL+ ++ +KA+ E+ L T DE
Sbjct: 1544 MRTQLEELEDELQA-TEDAKLRLEVNMQAMKAQ-----FERDL------------QTRDE 1585
Query: 452 DLDRRYNMEKEKLY--KIRLLQA-----RRNREIAILHRKIDEVPSRAELIQYQKRFIEL 504
N EK++L ++R L+A R+ R +A+ +K E+ + +L
Sbjct: 1586 Q-----NEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK-----------DL 1629
Query: 505 YRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN-SIHENFSQAMASPAARDQFLRQM 563
QI A +K + L + ++E+ S E F+Q+ S ++ L+ +
Sbjct: 1630 EAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKES----EKKLKSL 1685
Query: 564 EQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLE--------LLEKQRLYFKTV---KEF 612
E + +++ E+ ++ + RD+L D+ L EK+RL + +E
Sbjct: 1686 EAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEEL 1745
Query: 613 KEEGRKNEML 622
+EE E+L
Sbjct: 1746 EEEQSNMELL 1755
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 65.1 bits (157), Expect = 2e-10
Identities = 100/501 (19%), Positives = 216/501 (43%), Gaps = 65/501 (12%)
Query: 177 KPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATE- 235
K R+ K + E+L D + + ++ G +++ K+ + +T G + E
Sbjct: 41 KETRQSKLAEAKEQLTDHHPQTNPSV---GTAASDTKKKKINNGTNPETTTSGGCHSPED 97
Query: 236 --KADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTAS--SVGQIVGLCSAEIKQIVS 291
KA ++ LR E ++Q++ + L S +V Q+ G I ++
Sbjct: 98 EQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHD 157
Query: 292 EY---AEKQSELSAEESPEKLGTSQLHR--RKVISLNKQIAQKTKHLEELRASHTSLQAR 346
+ E + LSA + +K + ++ +L+ ++ + T EEL+ + LQ +
Sbjct: 158 SWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEK 217
Query: 347 YN--EAKKTLTELKTYSEKLDKEQAAL----EKIESKAD------PSILQNLRALVAMNE 394
E++K+ +L K E+A L ++++++AD S+ L+A V NE
Sbjct: 218 LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENE 277
Query: 395 -----------------------NLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDE 431
K QEQE K +EE R Q+E+ K E+ R +E
Sbjct: 278 LWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 337
Query: 432 KTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSR 491
E L M H+++ R ++++ KIR + R+ +E A + R+ +++ +
Sbjct: 338 MMWEKEEKIRELEEKM-HEQEKIREQEEKRQEEEKIREQEKRQEQE-AKMWRQEEKIREQ 395
Query: 492 AELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMA 551
E I+ Q+ ++ Q + ++ ++ + + +++ + ++ + + +
Sbjct: 396 EEKIREQEEMMQ--EQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEE 453
Query: 552 SPAARDQFLRQMEQIV---EGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKT 608
+++ +++ E+ + EG K + + ++QE KMRR + EK R K
Sbjct: 454 KIREQEEMMQEQEEKMGEQEG-KMCEQEAKMQEQEEKMRRQE---------EKIREQEKK 503
Query: 609 VKEFKEEGRKNEMLLSKVKAK 629
++E +E+ R+ E ++ + + K
Sbjct: 504 IREQEEKIREQEEMMQEQEEK 524
Score = 40.8 bits (94), Expect = 0.004
Identities = 59/296 (19%), Positives = 124/296 (41%), Gaps = 28/296 (9%)
Query: 179 RRKYKRHQGAEELLDEESRIHATLLEYGRRYG--FSRQSKMEKAEDKKTALPAGLSATEK 236
R++ K + E++ ++E +I + R+ + ++ KM + E+ + E+
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351
Query: 237 ADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEK 296
HE++++R EE+R + E+ R Q + E K E +
Sbjct: 352 K-MHEQEKIREQEEKRQEE----------EKIREQEKRQEQEAKMWRQEEKIREQEEKIR 400
Query: 297 QSELSAEESPEKLGTSQLHR-RKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLT 355
+ E +E EK+G + + + +Q + + E++R ++ + + ++
Sbjct: 401 EQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 356 ELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQ 415
++ EK+ +++ + + E+K +Q + E K +EQE K +EE R Q
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAK-----MQEQEEKMRRQEE-KIREQEKKIREQEEKIREQ 514
Query: 416 QEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQ 471
+E+ + E+ +EK E M E+ RR EK + ++RL Q
Sbjct: 515 EEMMQEQEEKMWEQEEKMCEQEE-------KMQEQEEKMRRQE-EKMREQEVRLRQ 562
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 64.3 bits (155), Expect = 3e-10
Identities = 108/484 (22%), Positives = 198/484 (40%), Gaps = 89/484 (18%)
Query: 159 IKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKME 218
+ R+E+ ++ D E+ K + +R Q AE L E + H+ L E Q++ E
Sbjct: 847 VTRQEEEMQAKED--ELQKTK---ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 219 ---KAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSV 275
+AE+ + L A E+ HE + EE R Q L + MA + L
Sbjct: 902 LYAEAEEMRVRLAAKKQELEEI-LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 276 GQIVGLCSAEIKQIVSEYAEKQSE---LSAEESPEKLGTSQLHRRKVISLNKQIAQKTKH 332
+ +++++ +E K+ E L ++ KL RK+ L ++I+ T +
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----RKL--LEERISDLTTN 1014
Query: 333 LEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSI------LQNL 386
L E +L N+ + ++EL+ +K +K + LEK++ K + + +L
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 387 RALVA-MNENLKSQEQEFKAHCREEMTRLQQEI---------------------ENLKAE 424
+A +A + L +E+E +A + RL EI E+L +E
Sbjct: 1075 QAQIAELKMQLAKKEEELQA----ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 425 RAPR----------GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARR 474
RA R G+E E TL S T E L+A+R
Sbjct: 1131 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------------------LRAKR 1172
Query: 475 NREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEK 534
+E+ +L + +DE +R+ Q Q+ + + + + ++ +QF LD K LEK
Sbjct: 1173 EQEVTVLKKALDE-ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1231
Query: 535 EISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQ 594
E + L QA +++E + ++ +++ K + + R +LND+
Sbjct: 1232 ENADLAGELRVLGQAK----------QEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
Query: 595 YLEL 598
+L
Sbjct: 1282 VHKL 1285
Score = 52.8 bits (125), Expect = 1e-06
Identities = 86/436 (19%), Positives = 178/436 (40%), Gaps = 44/436 (10%)
Query: 192 LDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATE---KADAHEEDELRAA 248
L++ R T +E + + +++ ED K L + A + + D DE
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 249 EEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEK 308
+ +++Q + + +E + A L +A K++ + + + + + +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRA--------LAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 309 LGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ 368
QL + L Q+ + LE+ RAS + A E +K L+ +L ++
Sbjct: 1642 EAIKQLRK-----LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 369 AALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPR 428
AA E+ +AD + L +A + + ++ Q+ K + +L++E+E +
Sbjct: 1697 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE------EQ 1749
Query: 429 GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREI-AILHRKIDE 487
G+ + +S T + +E R +K + + +L R+N+E+ + LH
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGA 1807
Query: 488 VPS--RAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHEN 545
V S ++ + + + +L Q+ +E KQ T DKK+ KEI L
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEARE-KQAATKSLKQKDKKL---KEILL------- 1856
Query: 546 FSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK---MRRDQLNDQYLELLEKQ 602
Q +Q+ Q E+ +KQ + ++E+ ++E++ R +L + E E
Sbjct: 1857 --QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1914
Query: 603 RLYFKTVKEFKEEGRK 618
+ V K + R+
Sbjct: 1915 EAMGREVNALKSKLRR 1930
Score = 50.1 bits (118), Expect = 6e-06
Identities = 78/382 (20%), Positives = 166/382 (43%), Gaps = 25/382 (6%)
Query: 216 KMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQR--IQSLMTKMTA--MANEESRLT 271
KM+ A+ K+ L A L+ + A + + L+ E I L + + A ++
Sbjct: 1082 KMQLAK-KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 272 ASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQ-KT 330
+G+ + E++ + A +Q EL A+ E + + S Q+ + +
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQ-ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ 1199
Query: 331 KHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALV 390
KH + + L+ ++ AK L + K EK + + A ++ +A + + L
Sbjct: 1200 KHAQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 391 AMNENLKSQ---EQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAM 447
A + L+S+ + +A +++ +LQ E+E++ + K + + +L+S +
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG-MLNEAEGKAIKLAKDVASLSSQL 1317
Query: 448 THDEDLDRRYNMEKEKLY-KIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIE-LY 505
++L + +K + K+R L+ RN L ++DE E Q +R I L
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNS----LQDQLDE---EMEAKQNLERHISTLN 1370
Query: 506 RQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMAS-PAARDQFLRQME 564
Q+S K+ + F + L++ K +KEI L +E + A +++ ++++
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 565 QIVEGIKQSRM---KMEKKKQE 583
+V + R +EKK+++
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRK 1452
Score = 50.1 bits (118), Expect = 6e-06
Identities = 74/355 (20%), Positives = 141/355 (39%), Gaps = 49/355 (13%)
Query: 284 AEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSL 343
AE K I S+YA+++ AE ++ K +SL + + + + EEL ++ L
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKET--------KALSLARALEEALEAKEELERTNKML 1509
Query: 344 QARYNEAKKTLTELKTYSEKLDKEQAA-----------LEKIESKADPSILQNLRALVAM 392
+A + + ++ +L+K + A LE++E + + LR V M
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1569
Query: 393 NENLKSQ-EQEFKA---HCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMT 448
+ LK Q E++ +A E+ +LQ+++ + E ++ L++
Sbjct: 1570 -QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKD 1628
Query: 449 HDEDLDRRYNMEKEKLYKIRLLQARR---NREIAILHRKIDEVPSRAELIQYQKRFIE-- 503
+ D +E + ++R LQA+ RE+ DE+ + A+ + + + +E
Sbjct: 1629 LELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD 1688
Query: 504 ---LYRQISAVHKETKQ--------------FFTLYNTLDDKKVYLEKEISLLNSIHENF 546
L ++A + KQ + N L D+K LE I+ + E
Sbjct: 1689 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA---QLEEEL 1745
Query: 547 SQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEK 601
+ + A +R+ Q E + Q+N+ R QL Q EL K
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
Score = 44.7 bits (104), Expect = 3e-04
Identities = 68/318 (21%), Positives = 146/318 (45%), Gaps = 37/318 (11%)
Query: 293 YAEKQSELSAEESPEKLGTSQLHRR-----KVISLNKQIAQKTKHLEELRASHTSLQ--- 344
+A++Q +L+A + ++ + L R ++ + K + Q T+ EE++A LQ
Sbjct: 806 FAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTK 865
Query: 345 ARYNEAKKTLTELKTYSEKLDKEQAAL-EKIESKAD-PSILQNLRA-LVAMNENLKSQEQ 401
R +A+ L EL+ +L +E+ L E+++++ + + + +R L A + L+
Sbjct: 866 ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 925
Query: 402 EFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEK 461
E +A EE R QQ L+AER + L + +E ++ +EK
Sbjct: 926 EMEARLEEEEDRGQQ----LQAERKKMAQQML--------DLEEQLEEEEAARQKLQLEK 973
Query: 462 EKL-YKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFT 520
KI+ L+ EI ++ + +++ +L+ ++R +L ++ ++ K
Sbjct: 974 VTAEAKIKKLE----DEILVMDDQNNKLSKERKLL--EERISDLTTNLAEEEEKAKNLTK 1027
Query: 521 LYN----TLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMK 576
L N + + +V L+KE + E + + A+ F Q+ + I + +M+
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDAS--DFHEQIADLQAQIAELKMQ 1084
Query: 577 MEKKKQENKMRRDQLNDQ 594
+ KK++E + +L+D+
Sbjct: 1085 LAKKEEELQAALARLDDE 1102
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 64.3 bits (155), Expect = 3e-10
Identities = 108/484 (22%), Positives = 198/484 (40%), Gaps = 89/484 (18%)
Query: 159 IKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKME 218
+ R+E+ ++ D E+ K + +R Q AE L E + H+ L E Q++ E
Sbjct: 854 VTRQEEEMQAKED--ELQKTK---ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 908
Query: 219 ---KAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSV 275
+AE+ + L A E+ HE + EE R Q L + MA + L
Sbjct: 909 LYAEAEEMRVRLAAKKQELEEI-LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967
Query: 276 GQIVGLCSAEIKQIVSEYAEKQSE---LSAEESPEKLGTSQLHRRKVISLNKQIAQKTKH 332
+ +++++ +E K+ E L ++ KL RK+ L ++I+ T +
Sbjct: 968 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----RKL--LEERISDLTTN 1021
Query: 333 LEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSI------LQNL 386
L E +L N+ + ++EL+ +K +K + LEK++ K + + +L
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 387 RALVA-MNENLKSQEQEFKAHCREEMTRLQQEI---------------------ENLKAE 424
+A +A + L +E+E +A + RL EI E+L +E
Sbjct: 1082 QAQIAELKMQLAKKEEELQA----ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 425 RAPR----------GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARR 474
RA R G+E E TL S T E L+A+R
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------------------LRAKR 1179
Query: 475 NREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEK 534
+E+ +L + +DE +R+ Q Q+ + + + + ++ +QF LD K LEK
Sbjct: 1180 EQEVTVLKKALDE-ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1238
Query: 535 EISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQ 594
E + L QA +++E + ++ +++ K + + R +LND+
Sbjct: 1239 ENADLAGELRVLGQAK----------QEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1288
Query: 595 YLEL 598
+L
Sbjct: 1289 VHKL 1292
Score = 52.8 bits (125), Expect = 1e-06
Identities = 86/436 (19%), Positives = 178/436 (40%), Gaps = 44/436 (10%)
Query: 192 LDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATE---KADAHEEDELRAA 248
L++ R T +E + + +++ ED K L + A + + D DE
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 249 EEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEK 308
+ +++Q + + +E + A L +A K++ + + + + + +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRA--------LAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Query: 309 LGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ 368
QL + L Q+ + LE+ RAS + A E +K L+ +L ++
Sbjct: 1649 EAIKQLRK-----LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 369 AALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPR 428
AA E+ +AD + L +A + + ++ Q+ K + +L++E+E +
Sbjct: 1704 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE------EQ 1756
Query: 429 GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREI-AILHRKIDE 487
G+ + +S T + +E R +K + + +L R+N+E+ + LH
Sbjct: 1757 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGA 1814
Query: 488 VPS--RAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHEN 545
V S ++ + + + +L Q+ +E KQ T DKK+ KEI L
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEARE-KQAATKSLKQKDKKL---KEILL------- 1863
Query: 546 FSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK---MRRDQLNDQYLELLEKQ 602
Q +Q+ Q E+ +KQ + ++E+ ++E++ R +L + E E
Sbjct: 1864 --QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1921
Query: 603 RLYFKTVKEFKEEGRK 618
+ V K + R+
Sbjct: 1922 EAMGREVNALKSKLRR 1937
Score = 50.1 bits (118), Expect = 6e-06
Identities = 78/382 (20%), Positives = 166/382 (43%), Gaps = 25/382 (6%)
Query: 216 KMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQR--IQSLMTKMTA--MANEESRLT 271
KM+ A+ K+ L A L+ + A + + L+ E I L + + A ++
Sbjct: 1089 KMQLAK-KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1147
Query: 272 ASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQ-KT 330
+G+ + E++ + A +Q EL A+ E + + S Q+ + +
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQ-ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ 1206
Query: 331 KHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALV 390
KH + + L+ ++ AK L + K EK + + A ++ +A + + L
Sbjct: 1207 KHAQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 391 AMNENLKSQ---EQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAM 447
A + L+S+ + +A +++ +LQ E+E++ + K + + +L+S +
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG-MLNEAEGKAIKLAKDVASLSSQL 1324
Query: 448 THDEDLDRRYNMEKEKLY-KIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIE-LY 505
++L + +K + K+R L+ RN L ++DE E Q +R I L
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEERNS----LQDQLDE---EMEAKQNLERHISTLN 1377
Query: 506 RQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMAS-PAARDQFLRQME 564
Q+S K+ + F + L++ K +KEI L +E + A +++ ++++
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 565 QIVEGIKQSRM---KMEKKKQE 583
+V + R +EKK+++
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRK 1459
Score = 50.1 bits (118), Expect = 6e-06
Identities = 74/355 (20%), Positives = 141/355 (39%), Gaps = 49/355 (13%)
Query: 284 AEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSL 343
AE K I S+YA+++ AE ++ K +SL + + + + EEL ++ L
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKET--------KALSLARALEEALEAKEELERTNKML 1516
Query: 344 QARYNEAKKTLTELKTYSEKLDKEQAA-----------LEKIESKADPSILQNLRALVAM 392
+A + + ++ +L+K + A LE++E + + LR V M
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1576
Query: 393 NENLKSQ-EQEFKA---HCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMT 448
+ LK Q E++ +A E+ +LQ+++ + E ++ L++
Sbjct: 1577 -QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKD 1635
Query: 449 HDEDLDRRYNMEKEKLYKIRLLQARR---NREIAILHRKIDEVPSRAELIQYQKRFIE-- 503
+ D +E + ++R LQA+ RE+ DE+ + A+ + + + +E
Sbjct: 1636 LELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD 1695
Query: 504 ---LYRQISAVHKETKQ--------------FFTLYNTLDDKKVYLEKEISLLNSIHENF 546
L ++A + KQ + N L D+K LE I+ + E
Sbjct: 1696 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA---QLEEEL 1752
Query: 547 SQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEK 601
+ + A +R+ Q E + Q+N+ R QL Q EL K
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1807
Score = 44.7 bits (104), Expect = 3e-04
Identities = 68/318 (21%), Positives = 146/318 (45%), Gaps = 37/318 (11%)
Query: 293 YAEKQSELSAEESPEKLGTSQLHRR-----KVISLNKQIAQKTKHLEELRASHTSLQ--- 344
+A++Q +L+A + ++ + L R ++ + K + Q T+ EE++A LQ
Sbjct: 813 FAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTK 872
Query: 345 ARYNEAKKTLTELKTYSEKLDKEQAAL-EKIESKAD-PSILQNLRA-LVAMNENLKSQEQ 401
R +A+ L EL+ +L +E+ L E+++++ + + + +R L A + L+
Sbjct: 873 ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 932
Query: 402 EFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEK 461
E +A EE R QQ L+AER + L + +E ++ +EK
Sbjct: 933 EMEARLEEEEDRGQQ----LQAERKKMAQQML--------DLEEQLEEEEAARQKLQLEK 980
Query: 462 EKL-YKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFT 520
KI+ L+ EI ++ + +++ +L+ ++R +L ++ ++ K
Sbjct: 981 VTAEAKIKKLE----DEILVMDDQNNKLSKERKLL--EERISDLTTNLAEEEEKAKNLTK 1034
Query: 521 LYN----TLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMK 576
L N + + +V L+KE + E + + A+ F Q+ + I + +M+
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDAS--DFHEQIADLQAQIAELKMQ 1091
Query: 577 MEKKKQENKMRRDQLNDQ 594
+ KK++E + +L+D+
Sbjct: 1092 LAKKEEELQAALARLDDE 1109
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 64.3 bits (155), Expect = 3e-10
Identities = 108/484 (22%), Positives = 198/484 (40%), Gaps = 89/484 (18%)
Query: 159 IKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKME 218
+ R+E+ ++ D E+ K + +R Q AE L E + H+ L E Q++ E
Sbjct: 854 VTRQEEEMQAKED--ELQKTK---ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 908
Query: 219 ---KAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSV 275
+AE+ + L A E+ HE + EE R Q L + MA + L
Sbjct: 909 LYAEAEEMRVRLAAKKQELEEI-LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 967
Query: 276 GQIVGLCSAEIKQIVSEYAEKQSE---LSAEESPEKLGTSQLHRRKVISLNKQIAQKTKH 332
+ +++++ +E K+ E L ++ KL RK+ L ++I+ T +
Sbjct: 968 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----RKL--LEERISDLTTN 1021
Query: 333 LEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSI------LQNL 386
L E +L N+ + ++EL+ +K +K + LEK++ K + + +L
Sbjct: 1022 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1081
Query: 387 RALVA-MNENLKSQEQEFKAHCREEMTRLQQEI---------------------ENLKAE 424
+A +A + L +E+E +A + RL EI E+L +E
Sbjct: 1082 QAQIAELKMQLAKKEEELQA----ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1137
Query: 425 RAPR----------GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARR 474
RA R G+E E TL S T E L+A+R
Sbjct: 1138 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------------------LRAKR 1179
Query: 475 NREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEK 534
+E+ +L + +DE +R+ Q Q+ + + + + ++ +QF LD K LEK
Sbjct: 1180 EQEVTVLKKALDE-ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1238
Query: 535 EISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQ 594
E + L QA +++E + ++ +++ K + + R +LND+
Sbjct: 1239 ENADLAGELRVLGQAK----------QEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1288
Query: 595 YLEL 598
+L
Sbjct: 1289 VHKL 1292
Score = 52.0 bits (123), Expect = 2e-06
Identities = 86/435 (19%), Positives = 177/435 (40%), Gaps = 44/435 (10%)
Query: 192 LDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATE---KADAHEEDELRAA 248
L++ R T +E + + +++ ED K L + A + + D DE
Sbjct: 1537 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1596
Query: 249 EEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEK 308
+ +++Q + + +E + A L +A K++ + + + + + +
Sbjct: 1597 KRRQLQRQLHEYETELEDERKQRA--------LAAAAKKKLEGDLKDLELQADSAIKGRE 1648
Query: 309 LGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ 368
QL + L Q+ + LE+ RAS + A E +K L+ +L ++
Sbjct: 1649 EAIKQLRK-----LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1703
Query: 369 AALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPR 428
AA E+ +AD + L +A + + ++ Q+ K + +L++E+E +
Sbjct: 1704 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE------EQ 1756
Query: 429 GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREI-AILHRKIDE 487
G+ + +S T + +E R +K + + +L R+N+E+ + LH
Sbjct: 1757 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGA 1814
Query: 488 VPS--RAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHEN 545
V S ++ + + + +L Q+ +E KQ T DKK+ KEI L
Sbjct: 1815 VKSKFKSTIAALEAKIAQLEEQVEQEARE-KQAATKSLKQKDKKL---KEILL------- 1863
Query: 546 FSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK---MRRDQLNDQYLELLEKQ 602
Q +Q+ Q E+ +KQ + ++E+ ++E++ R +L + E E
Sbjct: 1864 --QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1921
Query: 603 RLYFKTVKEFKEEGR 617
+ V K + R
Sbjct: 1922 EAMGREVNALKSKLR 1936
Score = 50.1 bits (118), Expect = 6e-06
Identities = 78/382 (20%), Positives = 166/382 (43%), Gaps = 25/382 (6%)
Query: 216 KMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQR--IQSLMTKMTA--MANEESRLT 271
KM+ A+ K+ L A L+ + A + + L+ E I L + + A ++
Sbjct: 1089 KMQLAK-KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1147
Query: 272 ASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQ-KT 330
+G+ + E++ + A +Q EL A+ E + + S Q+ + +
Sbjct: 1148 KRDLGEELEALKTELEDTLDSTATQQ-ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ 1206
Query: 331 KHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALV 390
KH + + L+ ++ AK L + K EK + + A ++ +A + + L
Sbjct: 1207 KHAQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1265
Query: 391 AMNENLKSQ---EQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAM 447
A + L+S+ + +A +++ +LQ E+E++ + K + + +L+S +
Sbjct: 1266 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG-MLNEAEGKAIKLAKDVASLSSQL 1324
Query: 448 THDEDLDRRYNMEKEKLY-KIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIE-LY 505
++L + +K + K+R L+ RN L ++DE E Q +R I L
Sbjct: 1325 QDTQELLQEETRQKLNVSTKLRQLEEERNS----LQDQLDE---EMEAKQNLERHISTLN 1377
Query: 506 RQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMAS-PAARDQFLRQME 564
Q+S K+ + F + L++ K +KEI L +E + A +++ ++++
Sbjct: 1378 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1437
Query: 565 QIVEGIKQSRM---KMEKKKQE 583
+V + R +EKK+++
Sbjct: 1438 DLVVDLDNQRQLVSNLEKKQRK 1459
Score = 50.1 bits (118), Expect = 6e-06
Identities = 74/355 (20%), Positives = 141/355 (39%), Gaps = 49/355 (13%)
Query: 284 AEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSL 343
AE K I S+YA+++ AE ++ K +SL + + + + EEL ++ L
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKET--------KALSLARALEEALEAKEELERTNKML 1516
Query: 344 QARYNEAKKTLTELKTYSEKLDKEQAA-----------LEKIESKADPSILQNLRALVAM 392
+A + + ++ +L+K + A LE++E + + LR V M
Sbjct: 1517 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1576
Query: 393 NENLKSQ-EQEFKA---HCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMT 448
+ LK Q E++ +A E+ +LQ+++ + E ++ L++
Sbjct: 1577 -QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKD 1635
Query: 449 HDEDLDRRYNMEKEKLYKIRLLQARR---NREIAILHRKIDEVPSRAELIQYQKRFIE-- 503
+ D +E + ++R LQA+ RE+ DE+ + A+ + + + +E
Sbjct: 1636 LELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD 1695
Query: 504 ---LYRQISAVHKETKQ--------------FFTLYNTLDDKKVYLEKEISLLNSIHENF 546
L ++A + KQ + N L D+K LE I+ + E
Sbjct: 1696 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA---QLEEEL 1752
Query: 547 SQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEK 601
+ + A +R+ Q E + Q+N+ R QL Q EL K
Sbjct: 1753 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1807
Score = 44.7 bits (104), Expect = 3e-04
Identities = 68/318 (21%), Positives = 146/318 (45%), Gaps = 37/318 (11%)
Query: 293 YAEKQSELSAEESPEKLGTSQLHRR-----KVISLNKQIAQKTKHLEELRASHTSLQ--- 344
+A++Q +L+A + ++ + L R ++ + K + Q T+ EE++A LQ
Sbjct: 813 FAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTK 872
Query: 345 ARYNEAKKTLTELKTYSEKLDKEQAAL-EKIESKAD-PSILQNLRA-LVAMNENLKSQEQ 401
R +A+ L EL+ +L +E+ L E+++++ + + + +R L A + L+
Sbjct: 873 ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 932
Query: 402 EFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEK 461
E +A EE R QQ L+AER + L + +E ++ +EK
Sbjct: 933 EMEARLEEEEDRGQQ----LQAERKKMAQQML--------DLEEQLEEEEAARQKLQLEK 980
Query: 462 EKL-YKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFT 520
KI+ L+ EI ++ + +++ +L+ ++R +L ++ ++ K
Sbjct: 981 VTAEAKIKKLE----DEILVMDDQNNKLSKERKLL--EERISDLTTNLAEEEEKAKNLTK 1034
Query: 521 LYN----TLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMK 576
L N + + +V L+KE + E + + A+ F Q+ + I + +M+
Sbjct: 1035 LKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDAS--DFHEQIADLQAQIAELKMQ 1091
Query: 577 MEKKKQENKMRRDQLNDQ 594
+ KK++E + +L+D+
Sbjct: 1092 LAKKEEELQAALARLDDE 1109
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 64.3 bits (155), Expect = 3e-10
Identities = 108/484 (22%), Positives = 198/484 (40%), Gaps = 89/484 (18%)
Query: 159 IKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKME 218
+ R+E+ ++ D E+ K + +R Q AE L E + H+ L E Q++ E
Sbjct: 847 VTRQEEEMQAKED--ELQKTK---ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETE 901
Query: 219 ---KAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSV 275
+AE+ + L A E+ HE + EE R Q L + MA + L
Sbjct: 902 LYAEAEEMRVRLAAKKQELEEI-LHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLE 960
Query: 276 GQIVGLCSAEIKQIVSEYAEKQSE---LSAEESPEKLGTSQLHRRKVISLNKQIAQKTKH 332
+ +++++ +E K+ E L ++ KL RK+ L ++I+ T +
Sbjct: 961 EEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKE----RKL--LEERISDLTTN 1014
Query: 333 LEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSI------LQNL 386
L E +L N+ + ++EL+ +K +K + LEK++ K + + +L
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADL 1074
Query: 387 RALVA-MNENLKSQEQEFKAHCREEMTRLQQEI---------------------ENLKAE 424
+A +A + L +E+E +A + RL EI E+L +E
Sbjct: 1075 QAQIAELKMQLAKKEEELQA----ALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSE 1130
Query: 425 RAPR----------GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARR 474
RA R G+E E TL S T E L+A+R
Sbjct: 1131 RAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE------------------LRAKR 1172
Query: 475 NREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEK 534
+E+ +L + +DE +R+ Q Q+ + + + + ++ +QF LD K LEK
Sbjct: 1173 EQEVTVLKKALDE-ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEK 1231
Query: 535 EISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQ 594
E + L QA +++E + ++ +++ K + + R +LND+
Sbjct: 1232 ENADLAGELRVLGQAK----------QEVEHKKKKLEAQVQELQSKCSDGERARAELNDK 1281
Query: 595 YLEL 598
+L
Sbjct: 1282 VHKL 1285
Score = 52.0 bits (123), Expect = 2e-06
Identities = 86/435 (19%), Positives = 177/435 (40%), Gaps = 44/435 (10%)
Query: 192 LDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATE---KADAHEEDELRAA 248
L++ R T +E + + +++ ED K L + A + + D DE
Sbjct: 1530 LEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEE 1589
Query: 249 EEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEK 308
+ +++Q + + +E + A L +A K++ + + + + + +
Sbjct: 1590 KRRQLQRQLHEYETELEDERKQRA--------LAAAAKKKLEGDLKDLELQADSAIKGRE 1641
Query: 309 LGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ 368
QL + L Q+ + LE+ RAS + A E +K L+ +L ++
Sbjct: 1642 EAIKQLRK-----LQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDL 1696
Query: 369 AALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPR 428
AA E+ +AD + L +A + + ++ Q+ K + +L++E+E +
Sbjct: 1697 AAAERARKQADLE-KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEE------EQ 1749
Query: 429 GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREI-AILHRKIDE 487
G+ + +S T + +E R +K + + +L R+N+E+ + LH
Sbjct: 1750 GNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQL--ERQNKELRSKLHEMEGA 1807
Query: 488 VPS--RAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHEN 545
V S ++ + + + +L Q+ +E KQ T DKK+ KEI L
Sbjct: 1808 VKSKFKSTIAALEAKIAQLEEQVEQEARE-KQAATKSLKQKDKKL---KEILL------- 1856
Query: 546 FSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK---MRRDQLNDQYLELLEKQ 602
Q +Q+ Q E+ +KQ + ++E+ ++E++ R +L + E E
Sbjct: 1857 --QVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESN 1914
Query: 603 RLYFKTVKEFKEEGR 617
+ V K + R
Sbjct: 1915 EAMGREVNALKSKLR 1929
Score = 50.1 bits (118), Expect = 6e-06
Identities = 78/382 (20%), Positives = 166/382 (43%), Gaps = 25/382 (6%)
Query: 216 KMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQR--IQSLMTKMTA--MANEESRLT 271
KM+ A+ K+ L A L+ + A + + L+ E I L + + A ++
Sbjct: 1082 KMQLAK-KEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQ 1140
Query: 272 ASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQ-KT 330
+G+ + E++ + A +Q EL A+ E + + S Q+ + +
Sbjct: 1141 KRDLGEELEALKTELEDTLDSTATQQ-ELRAKREQEVTVLKKALDEETRSHEAQVQEMRQ 1199
Query: 331 KHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALV 390
KH + + L+ ++ AK L + K EK + + A ++ +A + + L
Sbjct: 1200 KHAQAVEELTEQLE-QFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLE 1258
Query: 391 AMNENLKSQ---EQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAM 447
A + L+S+ + +A +++ +LQ E+E++ + K + + +L+S +
Sbjct: 1259 AQVQELQSKCSDGERARAELNDKVHKLQNEVESVTG-MLNEAEGKAIKLAKDVASLSSQL 1317
Query: 448 THDEDLDRRYNMEKEKLY-KIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIE-LY 505
++L + +K + K+R L+ RN L ++DE E Q +R I L
Sbjct: 1318 QDTQELLQEETRQKLNVSTKLRQLEEERNS----LQDQLDE---EMEAKQNLERHISTLN 1370
Query: 506 RQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMAS-PAARDQFLRQME 564
Q+S K+ + F + L++ K +KEI L +E + A +++ ++++
Sbjct: 1371 IQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELD 1430
Query: 565 QIVEGIKQSRM---KMEKKKQE 583
+V + R +EKK+++
Sbjct: 1431 DLVVDLDNQRQLVSNLEKKQRK 1452
Score = 50.1 bits (118), Expect = 6e-06
Identities = 74/355 (20%), Positives = 141/355 (39%), Gaps = 49/355 (13%)
Query: 284 AEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSL 343
AE K I S+YA+++ AE ++ K +SL + + + + EEL ++ L
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKET--------KALSLARALEEALEAKEELERTNKML 1509
Query: 344 QARYNEAKKTLTELKTYSEKLDKEQAA-----------LEKIESKADPSILQNLRALVAM 392
+A + + ++ +L+K + A LE++E + + LR V M
Sbjct: 1510 KAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNM 1569
Query: 393 NENLKSQ-EQEFKA---HCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMT 448
+ LK Q E++ +A E+ +LQ+++ + E ++ L++
Sbjct: 1570 -QALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKD 1628
Query: 449 HDEDLDRRYNMEKEKLYKIRLLQARR---NREIAILHRKIDEVPSRAELIQYQKRFIE-- 503
+ D +E + ++R LQA+ RE+ DE+ + A+ + + + +E
Sbjct: 1629 LELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEAD 1688
Query: 504 ---LYRQISAVHKETKQ--------------FFTLYNTLDDKKVYLEKEISLLNSIHENF 546
L ++A + KQ + N L D+K LE I+ + E
Sbjct: 1689 LMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIA---QLEEEL 1745
Query: 547 SQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEK 601
+ + A +R+ Q E + Q+N+ R QL Q EL K
Sbjct: 1746 EEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSK 1800
Score = 44.7 bits (104), Expect = 3e-04
Identities = 68/318 (21%), Positives = 146/318 (45%), Gaps = 37/318 (11%)
Query: 293 YAEKQSELSAEESPEKLGTSQLHRR-----KVISLNKQIAQKTKHLEELRASHTSLQ--- 344
+A++Q +L+A + ++ + L R ++ + K + Q T+ EE++A LQ
Sbjct: 806 FAKRQQQLTAMKVIQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTK 865
Query: 345 ARYNEAKKTLTELKTYSEKLDKEQAAL-EKIESKAD-PSILQNLRA-LVAMNENLKSQEQ 401
R +A+ L EL+ +L +E+ L E+++++ + + + +R L A + L+
Sbjct: 866 ERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILH 925
Query: 402 EFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEK 461
E +A EE R QQ L+AER + L + +E ++ +EK
Sbjct: 926 EMEARLEEEEDRGQQ----LQAERKKMAQQML--------DLEEQLEEEEAARQKLQLEK 973
Query: 462 EKL-YKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFT 520
KI+ L+ EI ++ + +++ +L+ ++R +L ++ ++ K
Sbjct: 974 VTAEAKIKKLE----DEILVMDDQNNKLSKERKLL--EERISDLTTNLAEEEEKAKNLTK 1027
Query: 521 LYN----TLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMK 576
L N + + +V L+KE + E + + A+ F Q+ + I + +M+
Sbjct: 1028 LKNKHESMISELEVRLKKEEKSRQEL-EKLKRKLEGDAS--DFHEQIADLQAQIAELKMQ 1084
Query: 577 MEKKKQENKMRRDQLNDQ 594
+ KK++E + +L+D+
Sbjct: 1085 LAKKEEELQAALARLDDE 1102
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 64.3 bits (155), Expect = 3e-10
Identities = 98/423 (23%), Positives = 177/423 (41%), Gaps = 64/423 (15%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
E EL AA E R+Q + + A+ L A+ + Q V + E ++ S E+ S+L
Sbjct: 242 ESELAAARE-RLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEK--SRVNERLSQLE 298
Query: 302 AEESPEKLGTSQL---HRRKVISLNKQIAQ-KTKHLEELRASHTSLQARYNEAKKTLTEL 357
E + + T L +++++ L K++ + K E +LQ+R E L E
Sbjct: 299 EERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEA 358
Query: 358 --KTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQ 415
KT E K A+E + S A +R + +L+ Q + K + E+ +LQ
Sbjct: 359 HSKTLEELAWKHHMAIEAVHSNA-------IRDKKKLQMDLEEQHNKDKLNLEEDKNQLQ 411
Query: 416 QEIENLK----------------AERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNM 459
QE+ENLK + R E+ L S E G + S E L ++
Sbjct: 412 QELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAE--GLIASLQDSQERLQNELDL 469
Query: 460 EKEKLYKIR---------LLQARRNREIAILHRKIDE---VPSRAELIQYQKRFIELYRQ 507
K+ L + + L Q R+ E I K +E V A ++ K L ++
Sbjct: 470 TKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI-KWTENLRQE 528
Query: 508 ISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIV 567
S + +E + +DKK + + + L + AARD + +++E ++
Sbjct: 529 CSKLREELR-----LQHEEDKKSAMSQLLQL---------KDREKNAARDSWQKKVEDLL 574
Query: 568 EGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVK 627
I + +E + +++ QL Q+ + E+QRL + ++E +E+ ++ L +
Sbjct: 575 NQISLLKQNLEIQLSQSQTSLQQLQAQFTQ--ERQRL-TQELEELEEQHQQRHKSLKEAH 631
Query: 628 AKA 630
A
Sbjct: 632 VLA 634
Score = 45.8 bits (107), Expect = 1e-04
Identities = 85/434 (19%), Positives = 174/434 (40%), Gaps = 63/434 (14%)
Query: 239 AHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQS 298
+ E +E+R E++++S ++ ++ RL + A ++ + E + Q
Sbjct: 35 SREVEEIRRKFEEKLRSF-GQLQVQFEKDKRLALEDL-------QAAHRREIQELLKSQQ 86
Query: 299 ELSAEESPEKLGTSQLHRRKVISLNKQI----AQKTKHLEELRASHTSLQARYNEAKKTL 354
+ SA + + +LHR +V SLNK + ++ K +E+ Q+ Y TL
Sbjct: 87 DHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELDTL 146
Query: 355 TELKTY---SEKLDKEQAALEKIESKADPSIL-------------------------QNL 386
+ + S + KE+ A + E + +IL Q L
Sbjct: 147 KRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKL 206
Query: 387 RALVAMNENLKSQEQEFKAHCRE-EMTRL--QQEIENLKA---ERAPRGDEKTLSSGEPP 440
+ +A+ EN Q+ +E EM L +E+E+ A ER + +
Sbjct: 207 QTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHI 266
Query: 441 GTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKR 500
G L + E + EK ++ + RL Q R A L K + + +++
Sbjct: 267 GMLQATQMTQEVTIKDLESEKSRVNE-RLSQLEEER--AFLRSKTQSLDE-----EQKQQ 318
Query: 501 FIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHEN------FSQAMASPA 554
+EL ++++ + ++++ L + + LE+E++ LN H + MA A
Sbjct: 319 ILELEKKVNEAKRTQQEYYE--RELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEA 376
Query: 555 ARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLE-KQRLYFKTVKEFK 613
+R +++ +++ K + +E+K + Q + E+LE K + + +
Sbjct: 377 VHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQ 436
Query: 614 EEGRKNEMLLSKVK 627
+ RK+E L +
Sbjct: 437 DMVRKSEQGLGSAE 450
Score = 45.8 bits (107), Expect = 1e-04
Identities = 83/391 (21%), Positives = 153/391 (39%), Gaps = 49/391 (12%)
Query: 243 DELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSA 302
+ELR E+ +S M+++ + + E S +++ ++++ + + L
Sbjct: 534 EELRLQHEEDKKSAMSQLLQLKDREKNAARDS-------WQKKVEDLLNQISLLKQNLEI 586
Query: 303 EESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKT-LTELKTYS 361
+ S + QL + ++ + T+ LEEL H Q R+ K+ + +T
Sbjct: 587 QLSQSQTSLQQLQAQ----FTQERQRLTQELEELEEQH---QQRHKSLKEAHVLAFQTME 639
Query: 362 EKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENL 421
E+ +KEQ ALE + + LQ +LK +E R EM +QE++ L
Sbjct: 640 EEKEKEQRALENHLQQKHSAELQ----------SLKDAHRESMEGFRIEM---EQELQTL 686
Query: 422 KAERAPRGDEKTLSSGEPPGTLTSAMTHDE----DLDRRYNMEKEKLYKIRLLQARRNRE 477
+ E G S L S + H DL R + ++ K+ L R
Sbjct: 687 RFELEDEGKAMLAS-------LRSELNHQHAAAIDLLRHNHHQELAAAKMEL-----ERS 734
Query: 478 IAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEIS 537
I I R+ E R +Q + R E IS + KE + + L + + KEI
Sbjct: 735 IDISRRQSKEHICRITDLQEELRHRE--HHISELDKEVQHLHENISALTKELEFKGKEIL 792
Query: 538 LLNSIHENFSQAMASPAARDQFLRQME-QIVEGIKQSRMKMEKKKQENKMRRDQLNDQYL 596
+ S E+ Q +R+ + + ++ I + + + ++ Q K + L
Sbjct: 793 RIRS--ESNQQIRLEEMEEKYLMRESKPEDIQMITELKAMLTERDQIIKKLIEDNKFYQL 850
Query: 597 ELLEKQRLYFKTVKEFKEEGRKNEMLLSKVK 627
EL+ ++ + K G N + K K
Sbjct: 851 ELVNRETNFNKVFNSSPTVGVINPLAKQKKK 881
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 64.3 bits (155), Expect = 3e-10
Identities = 98/423 (23%), Positives = 177/423 (41%), Gaps = 64/423 (15%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
E EL AA E R+Q + + A+ L A+ + Q V + E ++ S E+ S+L
Sbjct: 362 ESELAAARE-RLQQQASDLVLKASHIGMLQATQMTQEVTIKDLESEK--SRVNERLSQLE 418
Query: 302 AEESPEKLGTSQL---HRRKVISLNKQIAQ-KTKHLEELRASHTSLQARYNEAKKTLTEL 357
E + + T L +++++ L K++ + K E +LQ+R E L E
Sbjct: 419 EERAFLRSKTQSLDEEQKQQILELEKKVNEAKRTQQEYYERELKNLQSRLEEEVTQLNEA 478
Query: 358 --KTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQ 415
KT E K A+E + S A +R + +L+ Q + K + E+ +LQ
Sbjct: 479 HSKTLEELAWKHHMAIEAVHSNA-------IRDKKKLQMDLEEQHNKDKLNLEEDKNQLQ 531
Query: 416 QEIENLK----------------AERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNM 459
QE+ENLK + R E+ L S E G + S E L ++
Sbjct: 532 QELENLKEVLEDKLNTANQEIGHLQDMVRKSEQGLGSAE--GLIASLQDSQERLQNELDL 589
Query: 460 EKEKLYKIR---------LLQARRNREIAILHRKIDE---VPSRAELIQYQKRFIELYRQ 507
K+ L + + L Q R+ E I K +E V A ++ K L ++
Sbjct: 590 TKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKLKVDKMAHDLEI-KWTENLRQE 648
Query: 508 ISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIV 567
S + +E + +DKK + + + L + AARD + +++E ++
Sbjct: 649 CSKLREELR-----LQHEEDKKSAMSQLLQL---------KDREKNAARDSWQKKVEDLL 694
Query: 568 EGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSKVK 627
I + +E + +++ QL Q+ + E+QRL + ++E +E+ ++ L +
Sbjct: 695 NQISLLKQNLEIQLSQSQTSLQQLQAQFTQ--ERQRL-TQELEELEEQHQQRHKSLKEAH 751
Query: 628 AKA 630
A
Sbjct: 752 VLA 754
Score = 48.5 bits (114), Expect = 2e-05
Identities = 74/387 (19%), Positives = 159/387 (41%), Gaps = 41/387 (10%)
Query: 243 DELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSA 302
+ELR E+ +S M+++ + + E S +++ ++++ + + L
Sbjct: 654 EELRLQHEEDKKSAMSQLLQLKDREKNAARDS-------WQKKVEDLLNQISLLKQNLEI 706
Query: 303 EESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKT-LTELKTYS 361
+ S + QL + ++ + T+ LEEL H Q R+ K+ + +T
Sbjct: 707 QLSQSQTSLQQLQAQ----FTQERQRLTQELEELEEQH---QQRHKSLKEAHVLAFQTME 759
Query: 362 EKLDKEQAALEKIESKADPSILQNLRAL---------VAMNENLKSQEQEFKAHCREEMT 412
E+ +KEQ ALE + + LQ+L+ + M + L++ E + + +
Sbjct: 760 EEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQELQTLRFELEDEGKAMLA 819
Query: 413 RLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQ- 471
L+ E+ + A L + M + +D KE + +I LQ
Sbjct: 820 SLRSELNHQHAAAI-----DLLRHNHHQELAAAKMELERSIDISRRQSKEHICRITDLQE 874
Query: 472 --ARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKK 529
R I+ L +++ + + + F ++I + E+ Q L+ D
Sbjct: 875 ELRHREHHISELDKEVQHLHENISALTKELEF--KGKEILRIRSESNQQIRLHE--QDLN 930
Query: 530 VYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKK--KQENKMR 587
LEKE+ ++ + H M + + L +++I ++ S +ME+K +E+K
Sbjct: 931 KRLEKELDVMTADHLREKNIMRADFNKTNEL--LKEINAALQVSLEEMEEKYLMRESKPE 988
Query: 588 RDQLNDQYLELL-EKQRLYFKTVKEFK 613
Q+ + +L E+ ++ K +++ K
Sbjct: 989 DIQMITELKAMLTERDQIIKKLIEDNK 1015
Score = 45.8 bits (107), Expect = 1e-04
Identities = 85/434 (19%), Positives = 174/434 (40%), Gaps = 63/434 (14%)
Query: 239 AHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQS 298
+ E +E+R E++++S ++ ++ RL + A ++ + E + Q
Sbjct: 155 SREVEEIRRKFEEKLRSF-GQLQVQFEKDKRLALEDL-------QAAHRREIQELLKSQQ 206
Query: 299 ELSAEESPEKLGTSQLHRRKVISLNKQI----AQKTKHLEELRASHTSLQARYNEAKKTL 354
+ SA + + +LHR +V SLNK + ++ K +E+ Q+ Y TL
Sbjct: 207 DHSASVNKGQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLNKAQSFYERELDTL 266
Query: 355 TELKTY---SEKLDKEQAALEKIESKADPSIL-------------------------QNL 386
+ + S + KE+ A + E + +IL Q L
Sbjct: 267 KRSQLFTAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKL 326
Query: 387 RALVAMNENLKSQEQEFKAHCRE-EMTRL--QQEIENLKA---ERAPRGDEKTLSSGEPP 440
+ +A+ EN Q+ +E EM L +E+E+ A ER + +
Sbjct: 327 QTALAIAENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQQASDLVLKASHI 386
Query: 441 GTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKR 500
G L + E + EK ++ + RL Q R A L K + + +++
Sbjct: 387 GMLQATQMTQEVTIKDLESEKSRVNE-RLSQLEEER--AFLRSKTQSLDE-----EQKQQ 438
Query: 501 FIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHEN------FSQAMASPA 554
+EL ++++ + ++++ L + + LE+E++ LN H + MA A
Sbjct: 439 ILELEKKVNEAKRTQQEYYE--RELKNLQSRLEEEVTQLNEAHSKTLEELAWKHHMAIEA 496
Query: 555 ARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLE-KQRLYFKTVKEFK 613
+R +++ +++ K + +E+K + Q + E+LE K + + +
Sbjct: 497 VHSNAIRDKKKLQMDLEEQHNKDKLNLEEDKNQLQQELENLKEVLEDKLNTANQEIGHLQ 556
Query: 614 EEGRKNEMLLSKVK 627
+ RK+E L +
Sbjct: 557 DMVRKSEQGLGSAE 570
>gi|4885583 Rho-associated, coiled-coil containing protein kinase 1
[Homo sapiens]
Length = 1354
Score = 63.5 bits (153), Expect = 6e-10
Identities = 97/453 (21%), Positives = 183/453 (40%), Gaps = 78/453 (17%)
Query: 240 HEEDELRAAEEQRIQSLMTKMTAMANE------ESRLTASSVGQIVGLCSAEIKQIVSEY 293
H E +L+ EQ+ ++ K+ + E + R S+V QI ++ ++EY
Sbjct: 440 HNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTVSQIEKE-KMLLQHRINEY 498
Query: 294 AEK-----------QSELSA-----EESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELR 337
K ++E+S E+ + SQL K+ L KQ+ + L
Sbjct: 499 QRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTES 558
Query: 338 ASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLK 397
+ L+ + E K++++L++ + +L + LE +S+ D Q L+A++ +
Sbjct: 559 DTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQ-LQAILEAERRDR 617
Query: 398 SQEQEFKAHCREEMTRLQQEIENLKAE-RAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRR 456
+ E + +T LQ+E+++LK G+ K + H E +
Sbjct: 618 GHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQ---------DMLNHSE--KEK 666
Query: 457 YNMEKEKLYKIRLLQARRNREI----------AILHRKIDEVPS-------------RAE 493
N+E + YK++ LQ R +E+ H+ I+E S R
Sbjct: 667 NNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREA 726
Query: 494 LIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLL----------NSIH 543
+ + R +++ +Q S + + KQ L K +E E+ L +
Sbjct: 727 REKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLL 786
Query: 544 ENFSQAMASPAARDQFL-RQMEQIVEGIKQSRMKME-------KKKQENKMRRDQLNDQY 595
+N + A A + L +QM+Q + + +++ +E K+ + N+ + +L DQ
Sbjct: 787 QNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQL 846
Query: 596 LELLEKQRLYFKTVKEFKEE-GRKNEMLLSKVK 627
LY VKE KEE KN L K++
Sbjct: 847 EAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQ 879
Score = 40.0 bits (92), Expect = 0.007
Identities = 88/442 (19%), Positives = 177/442 (40%), Gaps = 92/442 (20%)
Query: 123 LVKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLS--------E 174
+ K + K + + +S ++ + +K L E+ + +EKA VV + +
Sbjct: 693 VTKARLTDKHQSIEEAKSVAMCEMEK--KLKEERE---AREKAENRVVQIEKQCSMLDVD 747
Query: 175 VYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSAT 234
+ + ++K + G +E +++E + + TL ++E+ +K+ L L
Sbjct: 748 LKQSQQKLEHLTGNKERMEDEVK-NLTL-------------QLEQESNKRLLLQNEL--- 790
Query: 235 EKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYA 294
K A E D L+ E+Q Q + T + E RL + Q+ + + + +
Sbjct: 791 -KTQAFEADNLKGLEKQMKQEINTLL-----EAKRLLEFELAQL----TKQYRGNEGQMR 840
Query: 295 EKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTL 354
E Q +L AE+ S L++ +V L ++I +K + E L+ +Q NE +
Sbjct: 841 ELQDQLEAEQY-----FSTLYKTQVKELKEEIEEKNR--ENLK----KIQELQNEKETLA 889
Query: 355 TELKTYSEKLDKEQAALEKIESK-------------------------------ADPSIL 383
T+L K + EQ A +E + A+ +
Sbjct: 890 TQLDLAETKAESEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEANSMLT 949
Query: 384 QNLRALVAMNENL----KSQEQEFKAHCREEMTRLQQEIE-NLKAERAPRG---DEKTLS 435
+++ L NE L K E+E+K EE++ L+ E N+ ER + ++
Sbjct: 950 KDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEI 1009
Query: 436 SGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELI 495
+ + +DL R+ E KL ++ L Q R ++ + + +A+L+
Sbjct: 1010 MNRKDFKIDRKKANTQDL-RKKEKENRKL-QLELNQEREKFNQMVVKHQKELNDMQAQLV 1067
Query: 496 QYQKRFIELYRQISAVHKETKQ 517
+ EL Q+++ + +Q
Sbjct: 1068 EECAHRNELQMQLASKESDIEQ 1089
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 61.6 bits (148), Expect = 2e-09
Identities = 96/458 (20%), Positives = 196/458 (42%), Gaps = 65/458 (14%)
Query: 185 HQGAEELLDE-ESRIHA--------TLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATE 235
HQ E L E E+++H T L+ Y Q +++ E + L + L +
Sbjct: 115 HQHQEALRRELEAQVHTIRILTCQKTELQMALYYS---QHAVKQLEGEARDLISRLHDSW 171
Query: 236 KADAHEEDELRAAEEQR------IQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQI 289
K E L A Q+ I+ L + A++ E R T + E+K+
Sbjct: 172 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT---------ITDEELKEK 222
Query: 290 VSEYAEKQSELSAEESPEKLGTSQLHRR----KVISLNKQIAQKTKHL-EELRASHTSLQ 344
++ EK + +E+S +L +L R+ K++ +Q+ + HL +EL++ LQ
Sbjct: 223 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 282
Query: 345 ARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFK 404
A+ E + + EK+ +++ +++ E K + K +EQE K
Sbjct: 283 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-------------EQEEKIREQEEK 329
Query: 405 AHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKL 464
+EE R Q+E+ K E+ R +E E L M E+ R + +
Sbjct: 330 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQ 389
Query: 465 YKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNT 524
KIR + +R E KI E R Q++ +++RQ + ++ ++
Sbjct: 390 EKIREQEEKRQEE-----EKIREQEKR------QEQEAKMWRQEEKIREQEEKIREQEKK 438
Query: 525 L--DDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
+ ++K++ +++I E Q +++ +R+ E+I ++ + + +KQ
Sbjct: 439 MWRQEEKIHEQEKIR-----EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQ 493
Query: 583 ENKMRR--DQLNDQYLELLEKQRLYFKTVKEFKEEGRK 618
E K+ R ++++DQ ++ E++ ++ ++ +E+ K
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEK 531
Score = 39.7 bits (91), Expect = 0.009
Identities = 66/386 (17%), Positives = 156/386 (40%), Gaps = 34/386 (8%)
Query: 147 QKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKR---HQGAEELLDEESRIHATLL 203
+K + + I+ K +K ++ +++ P+++ + H G +EL +++ A +
Sbjct: 228 EKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG-KELQSVSAKLQAQVE 286
Query: 204 E--YGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQ---RIQSLMT 258
E R ++ KM + E+K + E+ +E+++R EE+ + + +
Sbjct: 287 ENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWE 346
Query: 259 KMTAMANEESRLTASS-----VGQIVGLCSAEIKQIVSEYAEKQSELSAEES---PEKLG 310
K M +E + + +++ +I+++ + E++ EE EK+
Sbjct: 347 KEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 406
Query: 311 TSQLHRRKVISLNKQIAQKTKHLEELRAS-----------HTSLQARYNEAKKTLTELKT 359
+ + + + +Q + + E++R H + R E ++ E+
Sbjct: 407 EQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWR 466
Query: 360 YSEKLDKEQAALEKIESKADPSILQNLRALVAMNENL------KSQEQEFKAHCREEMTR 413
EK+ +++ + E + ++ V E K +EQE K +EE R
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIR 526
Query: 414 LQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQAR 473
Q+E + E+ +E E G M E + R+ +E+ KIR + +
Sbjct: 527 EQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEK 586
Query: 474 RNREIAILHRKIDEVPSRAELIQYQK 499
+ + + +++ + E++Q Q+
Sbjct: 587 IREQEEKIWEQEEKIREQEEMMQEQE 612
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 60.8 bits (146), Expect = 4e-09
Identities = 106/547 (19%), Positives = 221/547 (40%), Gaps = 63/547 (11%)
Query: 128 IETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQG 187
+E +EE ++++ Q L E + +E++ + + L +V + K +
Sbjct: 924 VEEEEERCQHLQAEKKKMQQNIQELEEQLE----EEESARQKLQLEKVTTEAKLKKLEEE 979
Query: 188 AEELLDEESRI--HATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDEL 245
L D+ ++ LLE R F+ + + + E+K +L + E E+ L
Sbjct: 980 QIILEDQNCKLAKEKKLLE-DRIAEFT--TNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 246 RAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEES 305
R E+QR Q L + + + L+ QI L A+I ++ + A+K+ EL A +
Sbjct: 1037 RREEKQR-QELEKTRRKLEGDSTDLS----DQIAEL-QAQIAELKMQLAKKEEELQAALA 1090
Query: 306 --PEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEK 363
E+ + +K+ L QI++ + LE RAS + + + + L LKT E
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELED 1150
Query: 364 LDKEQAALEKIESKADPSI-----------------LQNLRALVAMNENLKSQEQEFKAH 406
AA +++ SK + + +Q +R + +++ E
Sbjct: 1151 TLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKR 1210
Query: 407 CREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYN----MEKE 462
+ + + +Q +EN + E A G+ ++L ++N + E
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
Query: 463 KLYKIRLLQARRNREIAILHRK--------------IDEVPSRAELIQYQKR-FIELYRQ 507
K+ LQ + +L + ++ EL+Q + R + L +
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 508 ISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNS----IHENFSQAMASPAARDQFLRQM 563
+ V E F ++ K LEK+I+ L++ + + ++ ++ R++
Sbjct: 1331 LKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKL 1390
Query: 564 EQIVEGIKQ---SRMKMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNE 620
++ +EG+ Q ++ K ++ K R Q D L L+ QR ++ +++ +K +
Sbjct: 1391 QKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQR---QSACNLEKKQKKFD 1447
Query: 621 MLLSKVK 627
LL++ K
Sbjct: 1448 QLLAEEK 1454
Score = 60.1 bits (144), Expect = 6e-09
Identities = 105/485 (21%), Positives = 195/485 (40%), Gaps = 94/485 (19%)
Query: 217 MEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVG 276
+ +++ K + L SA E + + EL E ++ SL TK+ + +E++
Sbjct: 1289 LSQSDSKSSKLTKDFSALE-SQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEE 1347
Query: 277 QIVGLCSAEIKQIVSEYAE-----KQSELS------AEESPEKL-----GTSQLHRRKVI 320
+ + E KQI + +A+ K+ E S AEE KL G SQ H KV
Sbjct: 1348 EEEAKHNLE-KQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA 1406
Query: 321 SLNKQIAQKTKHLEEL----------RASHTSLQARYNEAKKTLTELKT----YSEKLDK 366
+ +K KT+ +EL R S +L+ + + + L E KT Y+E+ D+
Sbjct: 1407 AYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDR 1466
Query: 367 EQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMT-------------- 412
+A + E+KA S+ + L + L+ ++F+ + M+
Sbjct: 1467 AEAEAREKETKA-LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEK 1525
Query: 413 ---RLQQEIENLKAERAPRGDEKTLSSGE----PPGTLTSAMTHDEDLDRRYNMEKEK-- 463
L+Q++E +K + DE + + DL R +EK
Sbjct: 1526 SKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKK 1585
Query: 464 --LYKIRLLQA-----RRNREIAILHRK---IDEVPSRAELIQYQKRFIELYRQISAVHK 513
+ ++R ++A R+ R +A+ RK +D A + K E +Q+ +
Sbjct: 1586 QLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQA 1645
Query: 514 ETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQS 573
+ K LDD + E + +A ++ L+ ME + +++
Sbjct: 1646 QMKD---CMRELDDTRASRE--------------EILAQAKENEKKLKSMEAEMIQLQEE 1688
Query: 574 RMKMEKKKQENKMRRDQLNDQY--------LELLEKQRLYFKTV---KEFKEEGRKNEML 622
E+ K++ + RD+L D+ L L EK+RL + +E +EE E++
Sbjct: 1689 LAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELI 1748
Query: 623 LSKVK 627
++K
Sbjct: 1749 NDRLK 1753
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/324 (20%), Positives = 127/324 (39%), Gaps = 39/324 (12%)
Query: 317 RKVISLNKQIAQKTKHLEELRASHTSLQA----RYNEAKKTLTELKTYSEKLDKEQAALE 372
RK + +Q K L+ A++ L+ R K L ++ E++ ++ L
Sbjct: 796 RKAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELV 855
Query: 373 KIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEM---TRLQQEIENLKAERAPRG 429
K+ K L L M E L+SQ K +E++ T L E E L+A +
Sbjct: 856 KVREKQ----LAAENRLTEM-ETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKK 910
Query: 430 DEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVP 489
E + HD L+ R E+E+ ++ + + + I L +++E
Sbjct: 911 QE------------LEEICHD--LEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 490 SRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQA 549
S + +Q +K E + K+ L+D+ L KE LL F+
Sbjct: 957 SARQKLQLEKVTTE---------AKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTN 1007
Query: 550 MASPAARDQFLRQM----EQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRLY 605
+ + + L ++ E ++ +++ + EK++QE + R +L +L ++
Sbjct: 1008 LTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAEL 1067
Query: 606 FKTVKEFKEEGRKNEMLLSKVKAK 629
+ E K + K E L A+
Sbjct: 1068 QAQIAELKMQLAKKEEELQAALAR 1091
Score = 38.1 bits (87), Expect = 0.025
Identities = 43/202 (21%), Positives = 90/202 (44%), Gaps = 21/202 (10%)
Query: 231 LSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIV 290
L A K E D+ RA+ E+ + A A E + S +++ L + +
Sbjct: 1643 LQAQMKDCMRELDDTRASREE--------ILAQAKENEKKLKSMEAEMIQL---QEELAA 1691
Query: 291 SEYAEKQSELSAEESPEKLGTSQ----LHRRKVISLNKQIAQKTKHLEELRASHTSLQAR 346
+E A++Q++ +E +++ S L + L +IAQ + LEE + + + R
Sbjct: 1692 AERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDR 1751
Query: 347 YNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAH 406
+A + ++ T L+ E++ +K E+ QN V + E + + ++KA
Sbjct: 1752 LKKANLQIDQINT---DLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKAS 1808
Query: 407 ---CREEMTRLQQEIENLKAER 425
++ +L+++++N ER
Sbjct: 1809 ITALEAKIAQLEEQLDNETKER 1830
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 60.8 bits (146), Expect = 4e-09
Identities = 69/302 (22%), Positives = 138/302 (45%), Gaps = 17/302 (5%)
Query: 307 EKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTEL-KTYSEKLD 365
EKL T +L R + + K++ + LE+++ + +Q + + ++ L E K E L+
Sbjct: 95 EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALE 154
Query: 366 KEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAER 425
++ +E++ AD + L +A E +S +QE +A +E + L ++E LKAE
Sbjct: 155 AKERYMEEMADTADAIEMATLDKEMA-EERAESLQQEVEA-LKERVDELTTDLEILKAEI 212
Query: 426 APRGDEKTLSS------GEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIA 479
+G + SS E L A+ DL + EK++ K++ L ++N+E+
Sbjct: 213 EEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS---SSEKQEHVKLQKLMEKKNQELE 269
Query: 480 ILHRKIDEVPSRAELIQYQKRFIELYRQISAV--HKETKQFFTLYN-TLDDKKVYLEKEI 536
++ ++ + + + EL Q + EL Q+ A +E + T N L++K L + +
Sbjct: 270 VVRQQRERL--QEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETV 327
Query: 537 SLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYL 596
L +++E + + + LR+ + + K + QE Q +Y
Sbjct: 328 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYR 387
Query: 597 EL 598
+L
Sbjct: 388 QL 389
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 60.8 bits (146), Expect = 4e-09
Identities = 69/302 (22%), Positives = 138/302 (45%), Gaps = 17/302 (5%)
Query: 307 EKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTEL-KTYSEKLD 365
EKL T +L R + + K++ + LE+++ + +Q + + ++ L E K E L+
Sbjct: 209 EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALE 268
Query: 366 KEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAER 425
++ +E++ AD + L +A E +S +QE +A +E + L ++E LKAE
Sbjct: 269 AKERYMEEMADTADAIEMATLDKEMA-EERAESLQQEVEA-LKERVDELTTDLEILKAEI 326
Query: 426 APRGDEKTLSS------GEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIA 479
+G + SS E L A+ DL + EK++ K++ L ++N+E+
Sbjct: 327 EEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS---SSEKQEHVKLQKLMEKKNQELE 383
Query: 480 ILHRKIDEVPSRAELIQYQKRFIELYRQISAV--HKETKQFFTLYN-TLDDKKVYLEKEI 536
++ ++ + + + EL Q + EL Q+ A +E + T N L++K L + +
Sbjct: 384 VVRQQRERL--QEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETV 441
Query: 537 SLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYL 596
L +++E + + + LR+ + + K + QE Q +Y
Sbjct: 442 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYR 501
Query: 597 EL 598
+L
Sbjct: 502 QL 503
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 60.8 bits (146), Expect = 4e-09
Identities = 69/302 (22%), Positives = 138/302 (45%), Gaps = 17/302 (5%)
Query: 307 EKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTEL-KTYSEKLD 365
EKL T +L R + + K++ + LE+++ + +Q + + ++ L E K E L+
Sbjct: 95 EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALE 154
Query: 366 KEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAER 425
++ +E++ AD + L +A E +S +QE +A +E + L ++E LKAE
Sbjct: 155 AKERYMEEMADTADAIEMATLDKEMA-EERAESLQQEVEA-LKERVDELTTDLEILKAEI 212
Query: 426 APRGDEKTLSS------GEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIA 479
+G + SS E L A+ DL + EK++ K++ L ++N+E+
Sbjct: 213 EEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS---SSEKQEHVKLQKLMEKKNQELE 269
Query: 480 ILHRKIDEVPSRAELIQYQKRFIELYRQISAV--HKETKQFFTLYN-TLDDKKVYLEKEI 536
++ ++ + + + EL Q + EL Q+ A +E + T N L++K L + +
Sbjct: 270 VVRQQRERL--QEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETV 327
Query: 537 SLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYL 596
L +++E + + + LR+ + + K + QE Q +Y
Sbjct: 328 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYR 387
Query: 597 EL 598
+L
Sbjct: 388 QL 389
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 60.8 bits (146), Expect = 4e-09
Identities = 69/302 (22%), Positives = 138/302 (45%), Gaps = 17/302 (5%)
Query: 307 EKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTEL-KTYSEKLD 365
EKL T +L R + + K++ + LE+++ + +Q + + ++ L E K E L+
Sbjct: 229 EKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALE 288
Query: 366 KEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAER 425
++ +E++ AD + L +A E +S +QE +A +E + L ++E LKAE
Sbjct: 289 AKERYMEEMADTADAIEMATLDKEMA-EERAESLQQEVEA-LKERVDELTTDLEILKAEI 346
Query: 426 APRGDEKTLSS------GEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIA 479
+G + SS E L A+ DL + EK++ K++ L ++N+E+
Sbjct: 347 EEKGSDGAASSYQLKQLEEQNARLKDALVRMRDLS---SSEKQEHVKLQKLMEKKNQELE 403
Query: 480 ILHRKIDEVPSRAELIQYQKRFIELYRQISAV--HKETKQFFTLYN-TLDDKKVYLEKEI 536
++ ++ + + + EL Q + EL Q+ A +E + T N L++K L + +
Sbjct: 404 VVRQQRERL--QEELSQAESTIDELKEQVDAALGAEEMVEMLTDRNLNLEEKVRELRETV 461
Query: 537 SLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYL 596
L +++E + + + LR+ + + K + QE Q +Y
Sbjct: 462 GDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQQTIKKYR 521
Query: 597 EL 598
+L
Sbjct: 522 QL 523
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 60.5 bits (145), Expect = 5e-09
Identities = 98/459 (21%), Positives = 196/459 (42%), Gaps = 66/459 (14%)
Query: 185 HQGAEELLDE-ESRIHA--------TLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATE 235
HQ E L E E+++H T L+ Y Q +++ E + L + L +
Sbjct: 176 HQHQEALRRELEAQVHTIRILTCQKTELQMALYYS---QHAVKQLEGEARDLISRLHDSW 232
Query: 236 KADAHEEDELRAAEEQR------IQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQI 289
K E L A Q+ I+ L + A++ E R T + E+K+
Sbjct: 233 KFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNT---------ITDEELKEK 283
Query: 290 VSEYAEKQSELSAEESPEKLGTSQLHRR----KVISLNKQIAQKTKHL-EELRASHTSLQ 344
++ EK + +E+S +L +L R+ K++ +Q+ + HL +EL++ LQ
Sbjct: 284 NAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQ 343
Query: 345 ARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFK 404
A+ E + + EK+ +++ +++ E K + K +EQE K
Sbjct: 344 AQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-------------EQEEKIREQEEK 390
Query: 405 AHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKL 464
+EE R Q+E+ K E+ R +E E M E+ R + +
Sbjct: 391 IREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQ 450
Query: 465 YKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNT 524
KIR + +R E KI E R Q++ +++RQ + ++ ++
Sbjct: 451 EKIREQEEKRQEE-----EKIREQEKR------QEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 525 L--DDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEK-KK 581
+ ++K++ +++I E Q +++ +R+ E+I ++ + EK +K
Sbjct: 500 MWRQEEKIHEQEKIR-----EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRK 554
Query: 582 QENKMRR--DQLNDQYLELLEKQRLYFKTVKEFKEEGRK 618
QE KM R ++++DQ ++ E++ ++ ++ +E+ K
Sbjct: 555 QEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEK 593
Score = 41.2 bits (95), Expect = 0.003
Identities = 61/351 (17%), Positives = 147/351 (41%), Gaps = 43/351 (12%)
Query: 124 VKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVD-LSEVYKPRRKY 182
++R E E + +R ++K + ++ + KE+ I+ + + + E K R +
Sbjct: 398 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 457
Query: 183 KRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEE 242
++ Q E++ ++E R + + Q + + +++K ++ HE+
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW-------RQEEKIHEQ 510
Query: 243 DELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSA 302
+++R E+++ Q M + E+ EI + + E++ ++
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQE----------------EIWRQKEKIHEQEEKIRK 554
Query: 303 EESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSE 362
+E ++H ++ + +Q + + E++R ++ + + ++ + E
Sbjct: 555 QEEKMWRQEEKMHDQEE-KIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEE 613
Query: 363 KLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLK 422
K+ +++ + + E K +Q + E K +EQE K +EE R Q+E+ +
Sbjct: 614 KMGEQEEKMCEQEEK-----MQEQEEKMRRQEE-KIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 423 AERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLY--KIRLLQ 471
E+ +EK E M E+ RR ++EK++ ++RL Q
Sbjct: 668 EEKMWEQEEKMCEQEE-------KMQEQEEKMRR---QEEKMWEQEVRLRQ 708
Score = 39.7 bits (91), Expect = 0.009
Identities = 62/327 (18%), Positives = 128/327 (39%), Gaps = 29/327 (8%)
Query: 179 RRKYKRHQGAEELLDEESRIHATLLEYGRRYG-FSRQSKMEKAEDKKTALPAGLSATEKA 237
R++ K + E++ ++E +I + + RQ +M +++K + ++
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 238 DAHEEDELRAAEEQRIQSLMTKMTAMAN----EESRLTASSVGQIVGLCSAEIKQIVSEY 293
++E+ +E++I+ L KM EE R + + E K E
Sbjct: 425 KMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEE 484
Query: 294 AEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKT 353
++ E E EK+ + ++I ++ K EE + R E +
Sbjct: 485 KIREQEEKIREQEEKMWRQE----------EKIHEQEKIREEEKRQEQEEMWRQEEKIRE 534
Query: 354 LTELKTYSEKLDKEQAALEKIESKADPSILQNLRALVAMNENL-KSQEQEFKAHCREEMT 412
E+ EK+ +++ + K E K R M++ K +EQE K +EE
Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKM-------WRQEEKMHDQEEKIREQEEKVWRQEEKI 587
Query: 413 RLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQA 472
R Q+E + E+ +E T E G M E+ +E+ K+R +
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE------KMQEQEEKMRRQEE 641
Query: 473 RRNREIAILHRKIDEVPSRAELIQYQK 499
+ + + + +++ + E++Q Q+
Sbjct: 642 KIREQEKKIREQEEKIREQEEMMQEQE 668
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 60.1 bits (144), Expect = 6e-09
Identities = 90/468 (19%), Positives = 192/468 (41%), Gaps = 60/468 (12%)
Query: 171 DLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAG 230
DLS+ K + K + +E+L + ++ L+ +S ++ E++ L
Sbjct: 483 DLSQKLKETQS-KYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQD 541
Query: 231 LSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIV 290
L + ++++R EE+ ++ + EE SS ++ + E +
Sbjct: 542 LQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF 601
Query: 291 SEYAEKQ-----------SELSAEESPEKLGTSQLHRRKVISLNKQIAQ----------- 328
+Y E Q S+++ E S E + R + LNKQ+++
Sbjct: 602 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 661
Query: 329 -----KTKHLEEL------RASHTSLQARYN----EAKKTLTELKTYSEKLDKEQAALEK 373
K K LE++ +A H L N +A+ L+E+K+ K+ E L++
Sbjct: 662 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 721
Query: 374 I---ESKADPSILQNLRALVAMNENLKSQEQEF---KAHCRE---EMTRLQQEIENLKAE 424
+ + + SI ++L+ + + K E++ K H E+ +L++++ KA
Sbjct: 722 LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 781
Query: 425 RA----PRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLY-KIRLLQARRNREI- 478
PR + L S A E + + + E + + + Q +R +E
Sbjct: 782 MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENI 841
Query: 479 -AILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEIS 537
+L K EV EL+Q +F + +++ + + + L D K + KE++
Sbjct: 842 QTLLKSKEQEVN---ELLQ---KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVT 895
Query: 538 LLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK 585
L + SQ S ++ + +Q+E + + +KQ + ++ + K++++
Sbjct: 896 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQ 943
Score = 36.2 bits (82), Expect = 0.094
Identities = 68/350 (19%), Positives = 140/350 (40%), Gaps = 65/350 (18%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
+ L ++E +R Q L ++ + E L + + + S ++K+ S+Y E E+
Sbjct: 445 QKRLESSEAERKQ-LQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVL 503
Query: 302 AEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYS 361
+ + KLG ++ + H ELR + + + + L E +
Sbjct: 504 SVQKQMKLGL----------VSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNK 553
Query: 362 EKL-DKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
EK+ + E+ +E+ + ++ + + ++ + KA E+ Q+EI
Sbjct: 554 EKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMK 613
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHD-----EDLDRRYNMEKEKLYKIRLLQARRN 475
LK TL S MT + ED+ N ++L N
Sbjct: 614 LK------------------DTLKSQMTQEASDEAEDMKEAMNRMIDEL----------N 645
Query: 476 REIAILHRKIDEVPSRAELIQYQKRFIELYRQISA--VHK-ETKQFFTLYNTLDDKKVYL 532
++++ L + E ++AEL Y+KR + ++A +HK E ++ L N V
Sbjct: 646 KQVSELSQLYKE--AQAELEDYRKR--KSLEDVTAEYIHKAEHEKLMQLTN------VSR 695
Query: 533 EKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
K L+ + +S+ + L Q++Q+V+ K++ + + + Q
Sbjct: 696 AKAEDALSEMKSQYSKVLNE-------LTQLKQLVDAQKENSVSITEHLQ 738
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 60.1 bits (144), Expect = 6e-09
Identities = 90/468 (19%), Positives = 192/468 (41%), Gaps = 60/468 (12%)
Query: 171 DLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAG 230
DLS+ K + K + +E+L + ++ L+ +S ++ E++ L
Sbjct: 472 DLSQKLKETQS-KYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQD 530
Query: 231 LSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIV 290
L + ++++R EE+ ++ + EE SS ++ + E +
Sbjct: 531 LQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF 590
Query: 291 SEYAEKQ-----------SELSAEESPEKLGTSQLHRRKVISLNKQIAQ----------- 328
+Y E Q S+++ E S E + R + LNKQ+++
Sbjct: 591 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 650
Query: 329 -----KTKHLEEL------RASHTSLQARYN----EAKKTLTELKTYSEKLDKEQAALEK 373
K K LE++ +A H L N +A+ L+E+K+ K+ E L++
Sbjct: 651 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 710
Query: 374 I---ESKADPSILQNLRALVAMNENLKSQEQEF---KAHCRE---EMTRLQQEIENLKAE 424
+ + + SI ++L+ + + K E++ K H E+ +L++++ KA
Sbjct: 711 LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 770
Query: 425 RA----PRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLY-KIRLLQARRNREI- 478
PR + L S A E + + + E + + + Q +R +E
Sbjct: 771 MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENI 830
Query: 479 -AILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEIS 537
+L K EV EL+Q +F + +++ + + + L D K + KE++
Sbjct: 831 QTLLKSKEQEVN---ELLQ---KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVT 884
Query: 538 LLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK 585
L + SQ S ++ + +Q+E + + +KQ + ++ + K++++
Sbjct: 885 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQ 932
Score = 36.2 bits (82), Expect = 0.094
Identities = 68/350 (19%), Positives = 140/350 (40%), Gaps = 65/350 (18%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
+ L ++E +R Q L ++ + E L + + + S ++K+ S+Y E E+
Sbjct: 434 QKRLESSEAERKQ-LQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVL 492
Query: 302 AEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYS 361
+ + KLG ++ + H ELR + + + + L E +
Sbjct: 493 SVQKQMKLGL----------VSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNK 542
Query: 362 EKL-DKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
EK+ + E+ +E+ + ++ + + ++ + KA E+ Q+EI
Sbjct: 543 EKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMK 602
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHD-----EDLDRRYNMEKEKLYKIRLLQARRN 475
LK TL S MT + ED+ N ++L N
Sbjct: 603 LK------------------DTLKSQMTQEASDEAEDMKEAMNRMIDEL----------N 634
Query: 476 REIAILHRKIDEVPSRAELIQYQKRFIELYRQISA--VHK-ETKQFFTLYNTLDDKKVYL 532
++++ L + E ++AEL Y+KR + ++A +HK E ++ L N V
Sbjct: 635 KQVSELSQLYKE--AQAELEDYRKR--KSLEDVTAEYIHKAEHEKLMQLTN------VSR 684
Query: 533 EKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
K L+ + +S+ + L Q++Q+V+ K++ + + + Q
Sbjct: 685 AKAEDALSEMKSQYSKVLNE-------LTQLKQLVDAQKENSVSITEHLQ 727
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 60.1 bits (144), Expect = 6e-09
Identities = 90/468 (19%), Positives = 192/468 (41%), Gaps = 60/468 (12%)
Query: 171 DLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAG 230
DLS+ K + K + +E+L + ++ L+ +S ++ E++ L
Sbjct: 451 DLSQKLKETQS-KYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQD 509
Query: 231 LSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIV 290
L + ++++R EE+ ++ + EE SS ++ + E +
Sbjct: 510 LQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF 569
Query: 291 SEYAEKQ-----------SELSAEESPEKLGTSQLHRRKVISLNKQIAQ----------- 328
+Y E Q S+++ E S E + R + LNKQ+++
Sbjct: 570 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 629
Query: 329 -----KTKHLEEL------RASHTSLQARYN----EAKKTLTELKTYSEKLDKEQAALEK 373
K K LE++ +A H L N +A+ L+E+K+ K+ E L++
Sbjct: 630 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 689
Query: 374 I---ESKADPSILQNLRALVAMNENLKSQEQEF---KAHCRE---EMTRLQQEIENLKAE 424
+ + + SI ++L+ + + K E++ K H E+ +L++++ KA
Sbjct: 690 LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 749
Query: 425 RA----PRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLY-KIRLLQARRNREI- 478
PR + L S A E + + + E + + + Q +R +E
Sbjct: 750 MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENI 809
Query: 479 -AILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEIS 537
+L K EV EL+Q +F + +++ + + + L D K + KE++
Sbjct: 810 QTLLKSKEQEVN---ELLQ---KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVT 863
Query: 538 LLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK 585
L + SQ S ++ + +Q+E + + +KQ + ++ + K++++
Sbjct: 864 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQ 911
Score = 36.2 bits (82), Expect = 0.094
Identities = 68/350 (19%), Positives = 140/350 (40%), Gaps = 65/350 (18%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
+ L ++E +R Q L ++ + E L + + + S ++K+ S+Y E E+
Sbjct: 413 QKRLESSEAERKQ-LQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVL 471
Query: 302 AEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYS 361
+ + KLG ++ + H ELR + + + + L E +
Sbjct: 472 SVQKQMKLGL----------VSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNK 521
Query: 362 EKL-DKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
EK+ + E+ +E+ + ++ + + ++ + KA E+ Q+EI
Sbjct: 522 EKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMK 581
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHD-----EDLDRRYNMEKEKLYKIRLLQARRN 475
LK TL S MT + ED+ N ++L N
Sbjct: 582 LK------------------DTLKSQMTQEASDEAEDMKEAMNRMIDEL----------N 613
Query: 476 REIAILHRKIDEVPSRAELIQYQKRFIELYRQISA--VHK-ETKQFFTLYNTLDDKKVYL 532
++++ L + E ++AEL Y+KR + ++A +HK E ++ L N V
Sbjct: 614 KQVSELSQLYKE--AQAELEDYRKR--KSLEDVTAEYIHKAEHEKLMQLTN------VSR 663
Query: 533 EKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
K L+ + +S+ + L Q++Q+V+ K++ + + + Q
Sbjct: 664 AKAEDALSEMKSQYSKVLNE-------LTQLKQLVDAQKENSVSITEHLQ 706
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 60.1 bits (144), Expect = 6e-09
Identities = 90/468 (19%), Positives = 192/468 (41%), Gaps = 60/468 (12%)
Query: 171 DLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAG 230
DLS+ K + K + +E+L + ++ L+ +S ++ E++ L
Sbjct: 480 DLSQKLKETQS-KYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQD 538
Query: 231 LSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIV 290
L + ++++R EE+ ++ + EE SS ++ + E +
Sbjct: 539 LQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF 598
Query: 291 SEYAEKQ-----------SELSAEESPEKLGTSQLHRRKVISLNKQIAQ----------- 328
+Y E Q S+++ E S E + R + LNKQ+++
Sbjct: 599 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 658
Query: 329 -----KTKHLEEL------RASHTSLQARYN----EAKKTLTELKTYSEKLDKEQAALEK 373
K K LE++ +A H L N +A+ L+E+K+ K+ E L++
Sbjct: 659 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 718
Query: 374 I---ESKADPSILQNLRALVAMNENLKSQEQEF---KAHCRE---EMTRLQQEIENLKAE 424
+ + + SI ++L+ + + K E++ K H E+ +L++++ KA
Sbjct: 719 LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 778
Query: 425 RA----PRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLY-KIRLLQARRNREI- 478
PR + L S A E + + + E + + + Q +R +E
Sbjct: 779 MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENI 838
Query: 479 -AILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEIS 537
+L K EV EL+Q +F + +++ + + + L D K + KE++
Sbjct: 839 QTLLKSKEQEVN---ELLQ---KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVT 892
Query: 538 LLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK 585
L + SQ S ++ + +Q+E + + +KQ + ++ + K++++
Sbjct: 893 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQ 940
Score = 36.2 bits (82), Expect = 0.094
Identities = 68/350 (19%), Positives = 140/350 (40%), Gaps = 65/350 (18%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
+ L ++E +R Q L ++ + E L + + + S ++K+ S+Y E E+
Sbjct: 442 QKRLESSEAERKQ-LQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVL 500
Query: 302 AEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYS 361
+ + KLG ++ + H ELR + + + + L E +
Sbjct: 501 SVQKQMKLGL----------VSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNK 550
Query: 362 EKL-DKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
EK+ + E+ +E+ + ++ + + ++ + KA E+ Q+EI
Sbjct: 551 EKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMK 610
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHD-----EDLDRRYNMEKEKLYKIRLLQARRN 475
LK TL S MT + ED+ N ++L N
Sbjct: 611 LK------------------DTLKSQMTQEASDEAEDMKEAMNRMIDEL----------N 642
Query: 476 REIAILHRKIDEVPSRAELIQYQKRFIELYRQISA--VHK-ETKQFFTLYNTLDDKKVYL 532
++++ L + E ++AEL Y+KR + ++A +HK E ++ L N V
Sbjct: 643 KQVSELSQLYKE--AQAELEDYRKR--KSLEDVTAEYIHKAEHEKLMQLTN------VSR 692
Query: 533 EKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
K L+ + +S+ + L Q++Q+V+ K++ + + + Q
Sbjct: 693 AKAEDALSEMKSQYSKVLNE-------LTQLKQLVDAQKENSVSITEHLQ 735
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 60.1 bits (144), Expect = 6e-09
Identities = 90/468 (19%), Positives = 192/468 (41%), Gaps = 60/468 (12%)
Query: 171 DLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAG 230
DLS+ K + K + +E+L + ++ L+ +S ++ E++ L
Sbjct: 480 DLSQKLKETQS-KYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQD 538
Query: 231 LSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIV 290
L + ++++R EE+ ++ + EE SS ++ + E +
Sbjct: 539 LQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF 598
Query: 291 SEYAEKQ-----------SELSAEESPEKLGTSQLHRRKVISLNKQIAQ----------- 328
+Y E Q S+++ E S E + R + LNKQ+++
Sbjct: 599 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 658
Query: 329 -----KTKHLEEL------RASHTSLQARYN----EAKKTLTELKTYSEKLDKEQAALEK 373
K K LE++ +A H L N +A+ L+E+K+ K+ E L++
Sbjct: 659 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 718
Query: 374 I---ESKADPSILQNLRALVAMNENLKSQEQEF---KAHCRE---EMTRLQQEIENLKAE 424
+ + + SI ++L+ + + K E++ K H E+ +L++++ KA
Sbjct: 719 LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 778
Query: 425 RA----PRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLY-KIRLLQARRNREI- 478
PR + L S A E + + + E + + + Q +R +E
Sbjct: 779 MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENI 838
Query: 479 -AILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEIS 537
+L K EV EL+Q +F + +++ + + + L D K + KE++
Sbjct: 839 QTLLKSKEQEVN---ELLQ---KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVT 892
Query: 538 LLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK 585
L + SQ S ++ + +Q+E + + +KQ + ++ + K++++
Sbjct: 893 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQ 940
Score = 36.2 bits (82), Expect = 0.094
Identities = 68/350 (19%), Positives = 140/350 (40%), Gaps = 65/350 (18%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
+ L ++E +R Q L ++ + E L + + + S ++K+ S+Y E E+
Sbjct: 442 QKRLESSEAERKQ-LQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVL 500
Query: 302 AEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYS 361
+ + KLG ++ + H ELR + + + + L E +
Sbjct: 501 SVQKQMKLGL----------VSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNK 550
Query: 362 EKL-DKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
EK+ + E+ +E+ + ++ + + ++ + KA E+ Q+EI
Sbjct: 551 EKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMK 610
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHD-----EDLDRRYNMEKEKLYKIRLLQARRN 475
LK TL S MT + ED+ N ++L N
Sbjct: 611 LK------------------DTLKSQMTQEASDEAEDMKEAMNRMIDEL----------N 642
Query: 476 REIAILHRKIDEVPSRAELIQYQKRFIELYRQISA--VHK-ETKQFFTLYNTLDDKKVYL 532
++++ L + E ++AEL Y+KR + ++A +HK E ++ L N V
Sbjct: 643 KQVSELSQLYKE--AQAELEDYRKR--KSLEDVTAEYIHKAEHEKLMQLTN------VSR 692
Query: 533 EKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
K L+ + +S+ + L Q++Q+V+ K++ + + + Q
Sbjct: 693 AKAEDALSEMKSQYSKVLNE-------LTQLKQLVDAQKENSVSITEHLQ 735
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 60.1 bits (144), Expect = 6e-09
Identities = 90/468 (19%), Positives = 192/468 (41%), Gaps = 60/468 (12%)
Query: 171 DLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAG 230
DLS+ K + K + +E+L + ++ L+ +S ++ E++ L
Sbjct: 480 DLSQKLKETQS-KYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQD 538
Query: 231 LSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIV 290
L + ++++R EE+ ++ + EE SS ++ + E +
Sbjct: 539 LQNALEESERNKEKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLF 598
Query: 291 SEYAEKQ-----------SELSAEESPEKLGTSQLHRRKVISLNKQIAQ----------- 328
+Y E Q S+++ E S E + R + LNKQ+++
Sbjct: 599 EKYQEAQEEIMKLKDTLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAE 658
Query: 329 -----KTKHLEEL------RASHTSLQARYN----EAKKTLTELKTYSEKLDKEQAALEK 373
K K LE++ +A H L N +A+ L+E+K+ K+ E L++
Sbjct: 659 LEDYRKRKSLEDVTAEYIHKAEHEKLMQLTNVSRAKAEDALSEMKSQYSKVLNELTQLKQ 718
Query: 374 I---ESKADPSILQNLRALVAMNENLKSQEQEF---KAHCRE---EMTRLQQEIENLKAE 424
+ + + SI ++L+ + + K E++ K H E+ +L++++ KA
Sbjct: 719 LVDAQKENSVSITEHLQVITTLRTAAKEMEEKISNLKEHLASKEVEVAKLEKQLLEEKAA 778
Query: 425 RA----PRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLY-KIRLLQARRNREI- 478
PR + L S A E + + + E + + + Q +R +E
Sbjct: 779 MTDAMVPRSSYEKLQSSLESEVSVLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENI 838
Query: 479 -AILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEIS 537
+L K EV EL+Q +F + +++ + + + L D K + KE++
Sbjct: 839 QTLLKSKEQEVN---ELLQ---KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEVT 892
Query: 538 LLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENK 585
L + SQ S ++ + +Q+E + + +KQ + ++ + K++++
Sbjct: 893 KLKEALNSLSQLSYSTSSSKRQSQQLEALQQQVKQLQNQLAECKKQHQ 940
Score = 36.2 bits (82), Expect = 0.094
Identities = 68/350 (19%), Positives = 140/350 (40%), Gaps = 65/350 (18%)
Query: 242 EDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELS 301
+ L ++E +R Q L ++ + E L + + + S ++K+ S+Y E E+
Sbjct: 442 QKRLESSEAERKQ-LQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVL 500
Query: 302 AEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYS 361
+ + KLG ++ + H ELR + + + + L E +
Sbjct: 501 SVQKQMKLGL----------VSPESMDNYSHFHELRVTEEEINVLKQDLQNALEESERNK 550
Query: 362 EKL-DKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
EK+ + E+ +E+ + ++ + + ++ + KA E+ Q+EI
Sbjct: 551 EKVRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMK 610
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSAMTHD-----EDLDRRYNMEKEKLYKIRLLQARRN 475
LK TL S MT + ED+ N ++L N
Sbjct: 611 LK------------------DTLKSQMTQEASDEAEDMKEAMNRMIDEL----------N 642
Query: 476 REIAILHRKIDEVPSRAELIQYQKRFIELYRQISA--VHK-ETKQFFTLYNTLDDKKVYL 532
++++ L + E ++AEL Y+KR + ++A +HK E ++ L N V
Sbjct: 643 KQVSELSQLYKE--AQAELEDYRKR--KSLEDVTAEYIHKAEHEKLMQLTN------VSR 692
Query: 533 EKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQ 582
K L+ + +S+ + L Q++Q+V+ K++ + + + Q
Sbjct: 693 AKAEDALSEMKSQYSKVLNE-------LTQLKQLVDAQKENSVSITEHLQ 735
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 59.7 bits (143), Expect = 8e-09
Identities = 93/442 (21%), Positives = 184/442 (41%), Gaps = 58/442 (13%)
Query: 174 EVYKPRRKYKRHQGA--EELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGL 231
E+ +R R +GA EELL + + L+ + + + K E + TAL L
Sbjct: 713 ELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQ-----EDLLRKRERELTALKGAL 767
Query: 232 SATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVS 291
+ E D+L+ + +Q+L + L + S ++E Q +
Sbjct: 768 KEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASRSN-------TSEQDQAGT 820
Query: 292 EYAEKQSELSAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAK 351
E K L EE+ + G S+ R+V L +QI +E +A T +Y
Sbjct: 821 EMRVK---LLQEENEKLQGRSEELERRVAQLQRQIEDLKG--DEAKAKET--LKKYEGEI 873
Query: 352 KTLTELKTYSEKLDKE----QAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHC 407
+ L E ++ K +KE + ALE A ++ Q + ++E LK + ++
Sbjct: 874 RQLEEALVHARKEEKEAVSARRALENELEAAQGNLSQTTQEQKQLSEKLKEESEQ----- 928
Query: 408 REEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKI 467
+E++ RL+ E+EN ER G E + ++ T +L + + KEK
Sbjct: 929 KEQLRRLKNEMEN---ERWHLGKTIEKLQKEMADIVEASRTSTLELQNQLDEYKEK---- 981
Query: 468 RLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDD 527
RE+A + R++ E AE + + +++ ++ + +E + + +
Sbjct: 982 ------NRRELAEMQRQLKEKTLEAE--KSRLTAMKMQDEMRLMEEELRDYQRAQDEALT 1033
Query: 528 KKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKM- 586
K+ LE+ + L + A +D R ++Q+ + + Q M++E+++ + +
Sbjct: 1034 KRQLLEQTLKDLE------YELEAKSHLKDDRSRLVKQMEDKVSQLEMELEEERNNSDLL 1087
Query: 587 ------RRDQLNDQYLELLEKQ 602
R+Q+ ELL+++
Sbjct: 1088 SERISRSREQMEQLRNELLQER 1109
Score = 48.9 bits (115), Expect = 1e-05
Identities = 79/399 (19%), Positives = 177/399 (44%), Gaps = 59/399 (14%)
Query: 251 QRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLG 310
++IQ+L ++ A ++ +S ++ L + K + E AE Q +L E ++
Sbjct: 583 EKIQTLKSRAAGSAQGNNQ-ACNSTSEVKDLLEQKSKLTI-EVAELQRQLQLEVKNQQNI 640
Query: 311 TSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAA 370
+ R + +L + +Q + +EE L+ E +K L EL + K+++EQ
Sbjct: 641 KEERERMRA-NLEELRSQHNEKVEENSTLQQRLEESEGELRKNLEEL--FQVKMEREQHQ 697
Query: 371 LEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGD 430
E + + L + ++ K E K EE+ + +Q++++L + + D
Sbjct: 698 TEIRD------LQDQLSEMHDELDSAKRSEDREKGALIEELLQAKQDLQDLLIAKEEQED 751
Query: 431 -----EKTLSSGEPPGTLTSAMT-HDEDLDR---RYNMEKEKLYK--------IRLLQAR 473
E+ L++ + G L ++ HD+++D+ +Y+ E + L + + +L +R
Sbjct: 752 LLRKRERELTALK--GALKEEVSSHDQEMDKLKEQYDAELQALRESVEEATKNVEVLASR 809
Query: 474 RNRE----------IAILHRKIDEVPSRAELIQYQKRFIELYRQIS------AVHKET-K 516
N + +L + +++ R+E + ++R +L RQI A KET K
Sbjct: 810 SNTSEQDQAGTEMRVKLLQEENEKLQGRSE--ELERRVAQLQRQIEDLKGDEAKAKETLK 867
Query: 517 QFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMK 576
++ L++ V+ KE +A+++ A + L + + Q + +
Sbjct: 868 KYEGEIRQLEEALVHARKEEK----------EAVSARRALENELEAAQGNLSQTTQEQKQ 917
Query: 577 MEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEE 615
+ +K +E +++QL E+ ++ KT+++ ++E
Sbjct: 918 LSEKLKEESEQKEQLRRLKNEMENERWHLGKTIEKLQKE 956
Score = 44.3 bits (103), Expect = 3e-04
Identities = 75/410 (18%), Positives = 163/410 (39%), Gaps = 30/410 (7%)
Query: 187 GAEELLDEESRIH-ATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSAT-EKADAHEEDE 244
GA+ +EE + ATL+ R S S +K K + AT + +E
Sbjct: 488 GAQSKKEEEVKTATATLMLQNRATATSPDSGAKKISVKTFPSASNTQATPDLLKGQQELT 547
Query: 245 LRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVG-LCSAEIKQIVSEYAEKQSELSAE 303
+ EE Q L + + + T V + + + + + S Q+ S
Sbjct: 548 QQTNEETAKQILYNYLKEGSTDNDDATKRKVNLVFEKIQTLKSRAAGSAQGNNQACNSTS 607
Query: 304 ESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEK 363
E + L +V L +Q+ + K+ + ++ ++A L EL++ +
Sbjct: 608 EVKDLLEQKSKLTIEVAELQRQLQLEVKNQQNIKEERERMRAN-------LEELRSQHNE 660
Query: 364 LDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLK- 422
+E + L++ +++ + +NL L + + + E + +++++ + E+++ K
Sbjct: 661 KVEENSTLQQRLEESEGELRKNLEELFQVKMEREQHQTEIR-DLQDQLSEMHDELDSAKR 719
Query: 423 AERAPRGD--EKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAI 480
+E +G E+ L + + L A EDL R+ E + L+ E++
Sbjct: 720 SEDREKGALIEELLQAKQDLQDLLIAKEEQEDLLRKRERE------LTALKGALKEEVSS 773
Query: 481 LHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN 540
+++D++ QY L + K + + NT + + E + LL
Sbjct: 774 HDQEMDKLKE-----QYDAELQALRESVEEATKNVEVLASRSNTSEQDQAGTEMRVKLLQ 828
Query: 541 SIHENFSQAMASPAARDQFLRQMEQIVEGIK--QSRMKMEKKKQENKMRR 588
+E R + Q+++ +E +K +++ K KK E ++R+
Sbjct: 829 EENEKLQGRSEELERR---VAQLQRQIEDLKGDEAKAKETLKKYEGEIRQ 875
>gi|50658069 phosphodiesterase 4D interacting protein isoform 2
[Homo sapiens]
Length = 969
Score = 59.3 bits (142), Expect = 1e-08
Identities = 87/452 (19%), Positives = 189/452 (41%), Gaps = 63/452 (13%)
Query: 214 QSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQR------IQSLMTKMTAMANEE 267
+S + +DKK L + E ++ E ELR E+R + L+ + EE
Sbjct: 56 ESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEE 115
Query: 268 SRLTASSVGQIVGL------CSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRR--KV 319
SRL + ++ L C+ E+ + + + ++ ++ T L +R ++
Sbjct: 116 SRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRI 175
Query: 320 ISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ--------AAL 371
LN+ +A + + +E+L S Q + + T E++ +E+L K+Q
Sbjct: 176 EELNQSLAAQERLVEQL--SREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQ 233
Query: 372 EKIESKADPSILQNLRALVAMNENL--KSQEQEFKAHCREEMTRLQQ-EIENLKAERAPR 428
+ + + + ++ A N+ L K E ++ C +E ++ Q I+NLK
Sbjct: 234 QSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKE----- 288
Query: 429 GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEV 488
TL S E+L + + + + K+R + ++ LH
Sbjct: 289 -------------TLKSRERETEELYQVIEGQNDTMAKLR--EMLHQSQLGQLHSSEGTS 333
Query: 489 PSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN-SIHENFS 547
P+ Q Q ++L + E ++ + + + ++ + + + HE+
Sbjct: 334 PA-----QQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQ 388
Query: 548 QAMASPAARDQFLRQMEQIVEGI--KQSRMKMEKKKQENKMRRDQLNDQYL--ELLEKQR 603
Q AS + + ++Q+ E + K +++ + ++ N++R + N Q+L L K++
Sbjct: 389 QKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQ 448
Query: 604 LY--FKTVKEFKEEGRK----NEMLLSKVKAK 629
L F+ + ++++ K NEMLL K++ +
Sbjct: 449 LLQEFRELLQYRDNSDKTLEANEMLLEKLRQR 480
Score = 32.3 bits (72), Expect = 1.4
Identities = 83/410 (20%), Positives = 158/410 (38%), Gaps = 81/410 (19%)
Query: 191 LLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEE 250
LLD +S + + LE + RQ + + A+ K+ +A AHE ++ + A
Sbjct: 341 LLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCV------QFVEAAAHESEQQKEASW 394
Query: 251 QRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLG 310
+ Q L + +Q+ E K +L A E+ EK
Sbjct: 395 KHNQELRKAL--------------------------QQLQEELQNKSQQLRAWEA-EKYN 427
Query: 311 TSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAA 370
+ + + LN ++ K + L+E R LQ R N K L+ +
Sbjct: 428 EIRTQEQNIQHLNHSLSHKEQLLQEFREL---LQYRDNSDKT-----------LEANEML 473
Query: 371 LEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGD 430
LEK+ + + RA+ L+ +E+E + R + ++E L+
Sbjct: 474 LEKLRQRIHDKAVALERAIDEKFSALEEKEKELR-QLRLAVRERDHDLERLR-------- 524
Query: 431 EKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPS 490
LSS E + M E L R +E E+L + + + L +++ S
Sbjct: 525 -DVLSSNE------ATMQSMESLLRAKGLEVEQL-------STTCQNLQWLKEEMETKFS 570
Query: 491 RAELIQYQKRFIELYRQI-SAVHKETKQFFTLYNTLDDKKVYLEKEIS--LLNSIHENFS 547
R +QK + +Q+ +++H K+ L TL K + EI+ L +
Sbjct: 571 R-----WQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKER 625
Query: 548 QAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLE 597
+ R++ + + E ++G+ QS + ++QE++ ++L +E
Sbjct: 626 MLQDLLSDRNKQVLEHEMEIQGLLQS---VSTREQESQAAAEKLVQALME 672
>gi|157311604 phosphodiesterase 4D interacting protein isoform 1
[Homo sapiens]
Length = 2346
Score = 59.3 bits (142), Expect = 1e-08
Identities = 87/452 (19%), Positives = 189/452 (41%), Gaps = 63/452 (13%)
Query: 214 QSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQR------IQSLMTKMTAMANEE 267
+S + +DKK L + E ++ E ELR E+R + L+ + EE
Sbjct: 56 ESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQETEHVYELLENKIQLLQEE 115
Query: 268 SRLTASSVGQIVGL------CSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLHRR--KV 319
SRL + ++ L C+ E+ + + + ++ ++ T L +R ++
Sbjct: 116 SRLAKNEAARMAALVEAEKECNLELSEKLKGVTKNWEDVPGDQVKPDQYTEALAQRDKRI 175
Query: 320 ISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQ--------AAL 371
LN+ +A + + +E+L S Q + + T E++ +E+L K+Q
Sbjct: 176 EELNQSLAAQERLVEQL--SREKQQLLHLLEEPTSMEVQPMTEELLKQQKLNSHETTITQ 233
Query: 372 EKIESKADPSILQNLRALVAMNENL--KSQEQEFKAHCREEMTRLQQ-EIENLKAERAPR 428
+ + + + ++ A N+ L K E ++ C +E ++ Q I+NLK
Sbjct: 234 QSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELKCAQESSQKQDGTIQNLKE----- 288
Query: 429 GDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEV 488
TL S E+L + + + + K+R + ++ LH
Sbjct: 289 -------------TLKSRERETEELYQVIEGQNDTMAKLR--EMLHQSQLGQLHSSEGTS 333
Query: 489 PSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLN-SIHENFS 547
P+ Q Q ++L + E ++ + + + ++ + + + HE+
Sbjct: 334 PA-----QQQVALLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCVQFVEAAAHESEQ 388
Query: 548 QAMASPAARDQFLRQMEQIVEGI--KQSRMKMEKKKQENKMRRDQLNDQYL--ELLEKQR 603
Q AS + + ++Q+ E + K +++ + ++ N++R + N Q+L L K++
Sbjct: 389 QKEASWKHNQELRKALQQLQEELQNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQ 448
Query: 604 LY--FKTVKEFKEEGRK----NEMLLSKVKAK 629
L F+ + ++++ K NEMLL K++ +
Sbjct: 449 LLQEFRELLQYRDNSDKTLEANEMLLEKLRQR 480
Score = 32.3 bits (72), Expect = 1.4
Identities = 83/410 (20%), Positives = 158/410 (38%), Gaps = 81/410 (19%)
Query: 191 LLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEE 250
LLD +S + + LE + RQ + + A+ K+ +A AHE ++ + A
Sbjct: 341 LLDLQSALFCSQLEIQKLQRVVRQKERQLADAKQCV------QFVEAAAHESEQQKEASW 394
Query: 251 QRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSELSAEESPEKLG 310
+ Q L + +Q+ E K +L A E+ EK
Sbjct: 395 KHNQELRKAL--------------------------QQLQEELQNKSQQLRAWEA-EKYN 427
Query: 311 TSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAA 370
+ + + LN ++ K + L+E R LQ R N K L+ +
Sbjct: 428 EIRTQEQNIQHLNHSLSHKEQLLQEFREL---LQYRDNSDKT-----------LEANEML 473
Query: 371 LEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGD 430
LEK+ + + RA+ L+ +E+E + R + ++E L+
Sbjct: 474 LEKLRQRIHDKAVALERAIDEKFSALEEKEKELR-QLRLAVRERDHDLERLR-------- 524
Query: 431 EKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPS 490
LSS E + M E L R +E E+L + + + L +++ S
Sbjct: 525 -DVLSSNE------ATMQSMESLLRAKGLEVEQL-------STTCQNLQWLKEEMETKFS 570
Query: 491 RAELIQYQKRFIELYRQI-SAVHKETKQFFTLYNTLDDKKVYLEKEIS--LLNSIHENFS 547
R +QK + +Q+ +++H K+ L TL K + EI+ L +
Sbjct: 571 R-----WQKEQESIIQQLQTSLHDRNKEVEDLSATLLCKLGPGQSEIAEELCQRLQRKER 625
Query: 548 QAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLE 597
+ R++ + + E ++G+ QS + ++QE++ ++L +E
Sbjct: 626 MLQDLLSDRNKQVLEHEMEIQGLLQS---VSTREQESQAAAEKLVQALME 672
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 59.3 bits (142), Expect = 1e-08
Identities = 96/459 (20%), Positives = 192/459 (41%), Gaps = 45/459 (9%)
Query: 151 SLPEDDDFIKRKEKAIKTVVD-LSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRY 209
S+ ++ D ++R ++ +++ D L E K +H EE E H L E
Sbjct: 1439 SVAKEKDDLQRLQEVLQSESDQLKENIK--EIVAKHLETEE---ELKVAHCCLKEQEETI 1493
Query: 210 GFSRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESR 269
R + EK E + + + L A ++ E+ EEQ ++++ NE +
Sbjct: 1494 NELRVNLSEK-ETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQ 1552
Query: 270 LTASSVGQIVGLCSAEIK--QIVSEYAEKQSELSA-----EESPEKLGTSQLHRRKVISL 322
+ L S E K ++ + E Q E+ EE Q+ R ++
Sbjct: 1553 FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKEN 1612
Query: 323 NKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLDKEQAALEKIESKADPSI 382
K+I K K +E + A NE ++ + E++ E+ + ++ LE IE+
Sbjct: 1613 TKEIVAKMKESQEKEYQFLKMTA-VNETQEKMCEIEHLKEQFETQKLNLENIET------ 1665
Query: 383 LQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKAERAPRGDEKTLSSGEPPGT 442
+N+R ++ENL+ K E L+ E LK ER D+ + E T
Sbjct: 1666 -ENIRLTQILHENLEEMRSVTK-----ERDDLRSVEETLKVER----DQLKENLRE---T 1712
Query: 443 LTSAMTHDEDLD---RRYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQK 499
+T + E+L +E + K+R + + + EI+ + + ++ + ++ Q
Sbjct: 1713 ITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEH---SNDALKAQD 1769
Query: 500 RFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQF 559
I+ +I+ +H + +Q T+D + + ++ L+++ ++ + A + Q
Sbjct: 1770 LKIQEELRIAHMHLKEQQ-----ETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQE 1824
Query: 560 LRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLEL 598
L+ E + +K+ + +KK E + + Q+ DQ L L
Sbjct: 1825 LKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL 1863
Score = 53.9 bits (128), Expect = 4e-07
Identities = 97/523 (18%), Positives = 218/523 (41%), Gaps = 88/523 (16%)
Query: 124 VKRAIETKEEMGDYIRSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYK 183
+K ET++ + I + ++ Q + E+ + ++ +++V + +V + + K
Sbjct: 1649 LKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKEN 1708
Query: 184 RHQGAEELLDEESR---IHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLSATEKADAH 240
+ L+++ +H L E+ R EK + +S +K H
Sbjct: 1709 LRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNE--------ISNMQKDLEH 1760
Query: 241 EEDELRAAEEQRIQSLMTKMTAMANEESRLTASSVGQIVGLCSAEIKQIVSEYAEKQSEL 300
D L+A ++ +IQ + ++ M +E + T +++ IVSE +K S +
Sbjct: 1761 SNDALKA-QDLKIQEEL-RIAHMHLKEQQETID-----------KLRGIVSEKTDKLSNM 1807
Query: 301 SAEESPEKLGTSQLHRRKVISLNKQIAQKTKHLEELRASHTSLQARYNEAKKTLTELKTY 360
++ + + N ++ +K + L+ +L+ NE +K ++E++
Sbjct: 1808 ---------------QKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQL 1852
Query: 361 SEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIEN 420
+++ + L K+E ++NL ++ENL+ + K R+ + R+++ ++
Sbjct: 1853 KKQIKDQSLTLSKLE-------IENLNLAQKLHENLEEMKSVMKE--RDNLRRVEETLKL 1903
Query: 421 LKAERAPRGDEKTLSSGEPPGTLTSA----MTHDEDLDRRYNMEKEKLYKIRLLQARRNR 476
+ + E E L +A H E +D+ EK +I +Q ++
Sbjct: 1904 ERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDK 1963
Query: 477 EIAILHRKIDEVPSRAELIQYQKRFIELYR---QISAVHKETKQFFTLYNTLDDKKVYLE 533
L +KI E+ QK+ ++L R ++ HK+ + L KK +
Sbjct: 1964 SKDELQKKIQEL---------QKKELQLLRVKEDVNMSHKKINEMEQL------KKQFEA 2008
Query: 534 KEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIK---QSRMKMEKKKQENKMRRDQ 590
+ +S+ + +NF Q +++ + +E I+ + R ++ + K+ KM RDQ
Sbjct: 2009 QNLSMQSVRMDNF-----------QLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQ 2057
Query: 591 LNDQYLELL--EKQRLYFKTVKEFKEEGRKNEMLLSKVKAKAS 631
E++ ++Q K K +G+++ L ++ K S
Sbjct: 2058 FIATLREMIARDRQNHQVKPEKRLLSDGQQH--LTESLREKCS 2098
Score = 49.7 bits (117), Expect = 8e-06
Identities = 95/470 (20%), Positives = 195/470 (41%), Gaps = 67/470 (14%)
Query: 173 SEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGFSRQSKMEKAEDKKTALPAGLS 232
SE + + K K + ++ + +++ + LE ++ + +++ A ++ T L + +
Sbjct: 646 SENLELKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLID 705
Query: 233 ATEKADAHEEDELRAAEEQRIQSLMTKMTAMANEESRLTASSV--GQIVGLCSAEIKQIV 290
D EL E +I L ++ E L + ++ L S E++++
Sbjct: 706 GKVPKDLLCNLEL----EGKITDLQKELNKEVEENEALREEVILLSELKSLPS-EVERLR 760
Query: 291 SEYAEKQSELSAEESP-EKLGTSQLHRR-KVISLNKQIAQKTKHLEELRASHTSLQARYN 348
E +K EL S +KL + +H+ +V L ++I + L ++++ S +
Sbjct: 761 KEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQ 820
Query: 349 EAKKTLTELKTY-------SEKLDKEQAALEKIESKADPSILQNLRALVAMNENLKSQEQ 401
K + + +E++++E L K K D S L A+ L + Q
Sbjct: 821 NFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSS-------LGALKTELSYKTQ 873
Query: 402 EFKAHCRE------EMTRLQQEIENLKAERAPRGDEKTLSSGEPPGTLTSAMTHDEDLDR 455
E + RE EM +L++++EN + EKTL + + TL T ++ D
Sbjct: 874 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 933
Query: 456 RYNMEKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKET 515
+++ LQ R++ + +H D V + + + +E +Q H+ET
Sbjct: 934 LKQLQES-------LQIERDQLKSDIH---DTVNMNIDTQEQLRNALESLKQ----HQET 979
Query: 516 KQFFTLYNTLDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRM 575
NTL K + +E+S + EN + +D+F ++M I +
Sbjct: 980 ------INTLKSK---ISEEVSRNLHMEENTGE------TKDEFQQKMVGI-----DKKQ 1019
Query: 576 KMEKKKQENKMRRDQLNDQYLELLEKQRLYFKTVKEFKEEGRKNEMLLSK 625
+E K + + N E++E+QR F ++E E + E ++++
Sbjct: 1020 DLEAKNTQTLTADVKDN----EIIEQQRKIFSLIQEKNELQQMLESVIAE 1065
Score = 42.4 bits (98), Expect = 0.001
Identities = 62/318 (19%), Positives = 141/318 (44%), Gaps = 29/318 (9%)
Query: 327 AQKTKHLEELRASHTSLQARYNEAKKTLTELKTYSEKLD---KEQAALEKIES-----KA 378
A K + E + + SL+A Y+ +L+T E+++ KE+ L++ E+ K
Sbjct: 487 ATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKK 546
Query: 379 DPSI-----LQNLRALV----AMNENLK---SQEQEFKAHCREEMTRLQQEIENLKAERA 426
D + + NL+ LV N++L+ S + E +++ +LQ+ I++ K E
Sbjct: 547 DQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENI 606
Query: 427 PRGDEKTLSSGEPPGTLTSAMTHDEDLDRRYNMEKEKLYKIRLLQARRNREIAILHRKI- 485
+L S E P + + E + E L L + +E+A ++++
Sbjct: 607 KMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQME 666
Query: 486 -DEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTLDDKKVYLEKEISLLNSIHE 544
D +++L +K ++L +++ + E + +L + K + E L
Sbjct: 667 NDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLE---LEGKIT 723
Query: 545 NFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRDQLNDQYLELLEKQRL 604
+ + + ++ LR+ ++ +K ++E+ ++E + + ++L ++ EK +L
Sbjct: 724 DLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEEL---HIITSEKDKL 780
Query: 605 YFKTV-KEFKEEGRKNEM 621
+ + V KE + +G E+
Sbjct: 781 FSEVVHKESRVQGLLEEI 798
Score = 40.8 bits (94), Expect = 0.004
Identities = 110/571 (19%), Positives = 216/571 (37%), Gaps = 86/571 (15%)
Query: 94 LPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYI--RSYSVSQFQKTYS 151
L R + L+ + + ++ + L K ET +++ + I ++ +S QK
Sbjct: 1903 LERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLD 1962
Query: 152 LPEDDDFIKRKEKAIKTVVDLSEVYKPRRKYKRHQGAEELLDEESRIHATLLEYGRRYGF 211
+D+ K+ ++ K + L V + + E L ++ ++ R F
Sbjct: 1963 KSKDE-LQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQSVRMDNF 2021
Query: 212 SRQSKMEKAEDKKTALPAGLSATEKADAHEEDELRAAEE----QRIQSLMTKMTAMANE- 266
K+ ++ ++ + A E DELR +E +R Q + T +A +
Sbjct: 2022 QLTKKLHESLEEIRIV-----------AKERDELRRIKESLKMERDQFIATLREMIARDR 2070
Query: 267 -------ESRLTASSVGQIVGL----CSAEIKQIVSEYAEKQSELSAEESPEKLGTSQLH 315
E RL + + CS IK+++ Y+E ++ E L L
Sbjct: 2071 QNHQVKPEKRLLSDGQQHLTESLREKCS-RIKELLKRYSEM------DDHYECLNRLSLD 2123
Query: 316 RRKVISLNKQIAQK-----------TKHLEELRASHTSLQARYNEAKKTLTELKTYSEKL 364
K I K+++ + TKH+E+L ++ ++ K L + +Y K+
Sbjct: 2124 LEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTKI 2183
Query: 365 DKEQ-AALEKIESKADPSILQNLRALVAMNENLKSQEQEFKAHCREEMTRLQQEIENLKA 423
+EQ ++ K E + + L+ + Q + C L+ N
Sbjct: 2184 KEEQHESINKFEMDFIDEVEKQKELLIKI--------QHLQQDCDVPSRELRDLKLNQNM 2235
Query: 424 ERAPRGDEKTLSSGEPPGTLT---------SAMTH--DEDLDRRYNMEKEK----LYKIR 468
+ K S E P T MT +E L+ R+++EK K R
Sbjct: 2236 DLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDR 2295
Query: 469 LLQAR---RNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNTL 525
+ Q NR IAI++ + A + + E + + ++ ++ ++ F Y TL
Sbjct: 2296 ICQVNNFFNNRIIAIMNESTEFEERSATISK------EWEQDLKSLKEKNEKLFKNYQTL 2349
Query: 526 DDKKVYLEKEISLLNSIHENFSQAMASPAAR--DQFLRQMEQIVEGIKQSRMKMEKKKQE 583
K L + + +N + + S A + + +R++E + K+S M E K +
Sbjct: 2350 ---KTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAMHKESKIIK 2406
Query: 584 NKMRRDQLNDQYLELLEKQRLYFKTVKEFKE 614
+ + ND +L K K +++ KE
Sbjct: 2407 MQKELEVTNDIIAKLQAKVHESNKCLEKTKE 2437
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,559,611
Number of Sequences: 37866
Number of extensions: 939816
Number of successful extensions: 6828
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 850
Number of HSP's that attempted gapping in prelim test: 4667
Number of HSP's gapped (non-prelim): 2198
length of query: 631
length of database: 18,247,518
effective HSP length: 108
effective length of query: 523
effective length of database: 14,157,990
effective search space: 7404628770
effective search space used: 7404628770
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.