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Search of human proteins with 82617626
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82617626 paralemmin 2 isoform b [Homo sapiens]
(379 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82617626 paralemmin 2 isoform b [Homo sapiens] 741 0.0
gi|82524851 paralemmin 2 isoform a [Homo sapiens] 723 0.0
gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 252 4e-67
gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 252 4e-67
gi|93141031 paralemmin isoform 1 [Homo sapiens] 231 6e-61
gi|93141029 paralemmin isoform 2 [Homo sapiens] 188 8e-48
gi|8923243 palmdelphin [Homo sapiens] 158 7e-39
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 71 1e-12
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 56 6e-08
gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens] 56 6e-08
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens] 54 3e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 50 3e-06
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 50 3e-06
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 50 4e-06
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 49 6e-06
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 48 2e-05
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 47 2e-05
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 47 3e-05
gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo sa... 47 4e-05
gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo sa... 47 4e-05
gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo sa... 46 5e-05
gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo sa... 46 5e-05
gi|148746195 trichohyalin [Homo sapiens] 46 5e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 46 6e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 46 6e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 46 6e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 46 6e-05
gi|42794779 myosin 18A isoform b [Homo sapiens] 45 1e-04
gi|28416946 myosin 18A isoform a [Homo sapiens] 45 1e-04
gi|110611218 ribosome binding protein 1 [Homo sapiens] 45 1e-04
>gi|82617626 paralemmin 2 isoform b [Homo sapiens]
Length = 379
Score = 741 bits (1912), Expect = 0.0
Identities = 379/379 (100%), Positives = 379/379 (100%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG
Sbjct: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS
Sbjct: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
Query: 121 FKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVY 180
FKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVY
Sbjct: 121 FKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVY 180
Query: 181 EVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKE 240
EVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKE
Sbjct: 181 EVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKE 240
Query: 241 AKLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGY 300
AKLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGY
Sbjct: 241 AKLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGY 300
Query: 301 DETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLA 360
DETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLA
Sbjct: 301 DETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLA 360
Query: 361 TEPAPGTQKKKRCQCCVVM 379
TEPAPGTQKKKRCQCCVVM
Sbjct: 361 TEPAPGTQKKKRCQCCVVM 379
>gi|82524851 paralemmin 2 isoform a [Homo sapiens]
Length = 413
Score = 723 bits (1867), Expect = 0.0
Identities = 379/413 (91%), Positives = 379/413 (91%), Gaps = 34/413 (8%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG
Sbjct: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS
Sbjct: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
Query: 121 FKDFQKGFSSTDG----------------------------------AVYAMEINVEKDK 146
FKDFQKGFSSTDG AVYAMEINVEKDK
Sbjct: 121 FKDFQKGFSSTDGDAVNYISSQLPDLPILCSRTAEPSPGQDGTSRAAAVYAMEINVEKDK 180
Query: 147 QTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQ 206
QTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQ
Sbjct: 181 QTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQ 240
Query: 207 KAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPS 266
KAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPS
Sbjct: 241 KAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPS 300
Query: 267 AAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTD 326
AAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTD
Sbjct: 301 AAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTD 360
Query: 327 VSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLATEPAPGTQKKKRCQCCVVM 379
VSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLATEPAPGTQKKKRCQCCVVM
Sbjct: 361 VSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLATEPAPGTQKKKRCQCCVVM 413
>gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens]
Length = 1090
Score = 252 bits (643), Expect = 4e-67
Identities = 173/353 (49%), Positives = 203/353 (57%), Gaps = 20/353 (5%)
Query: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA
Sbjct: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
Query: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 122
EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK
Sbjct: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
Query: 123 DFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEV 182
DFQKGFSSTDG +N Q + IL + T P + G + V +
Sbjct: 121 DFQKGFSSTDGDA----VNY-ISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVL-L 174
Query: 183 RSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAK 242
+ G E+ + T + I+K Q S + +L P L + K
Sbjct: 175 KEG----ESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHK 230
Query: 243 LEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDE 302
+ S + S PG + P A P + + D + +++ DE
Sbjct: 231 NMEIEVSVAECKS-VPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDE 289
Query: 303 TIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSG--RPVSDTTEPSSPE 353
++A S + T S+ + A LV G PV + T+P E
Sbjct: 290 VLEANCC-------DSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTE 335
>gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens]
Length = 1103
Score = 252 bits (643), Expect = 4e-67
Identities = 173/353 (49%), Positives = 203/353 (57%), Gaps = 20/353 (5%)
Query: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA
Sbjct: 1 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 60
Query: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 122
EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK
Sbjct: 61 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 120
Query: 123 DFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEV 182
DFQKGFSSTDG +N Q + IL + T P + G + V +
Sbjct: 121 DFQKGFSSTDGDA----VNY-ISSQLPDLPILCSRTAEPSPGQDGTSRAAGVGWENVL-L 174
Query: 183 RSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAK 242
+ G E+ + T + I+K Q S + +L P L + K
Sbjct: 175 KEG----ESASNATETSGPDMTIKKPPQLSEDDIWLKSEGDNYSATLLEPAASSLSPDHK 230
Query: 243 LEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDE 302
+ S + S PG + P A P + + D + +++ DE
Sbjct: 231 NMEIEVSVAECKS-VPGITSTPHPMDHPSAFYSPPHNGLLTDHHESLDNDVAREIRYLDE 289
Query: 303 TIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSG--RPVSDTTEPSSPE 353
++A S + T S+ + A LV G PV + T+P E
Sbjct: 290 VLEANCC-------DSAVDGTYNGTSSPEPGAVVLVGGLSPPVHEATQPEPTE 335
>gi|93141031 paralemmin isoform 1 [Homo sapiens]
Length = 387
Score = 231 bits (590), Expect = 6e-61
Identities = 161/414 (38%), Positives = 227/414 (54%), Gaps = 70/414 (16%)
Query: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 63
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
Query: 64 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQ-ISAKEQIIL----------- 111
+E RRQ ++DE + + LED++ RLE+EI+ LE +S +AKE
Sbjct: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSPVRAPAPSP 125
Query: 112 -EKLKETEKSFKDFQ--------KGFSST-----DG------AVYAMEINVEKDKQTGET 151
++ ++TE Q K S+T DG A+Y++EI VEKDK TGET
Sbjct: 126 AKEERKTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSPMMKAAMYSVEITVEKDKVTGET 185
Query: 152 KILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKDVEELIQKAGQS 211
++LS++T+ P G+KVY+D TKVV+ V GT ENG+H LS+ +V+ELI KA +
Sbjct: 186 RVLSSTTLLPRQPLPLGIKVYEDETKVVHAV--DGTA-ENGIHPLSSSEVDELIHKADEV 242
Query: 212 SLG-----GGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPG-QQAQAP 265
+L G R + + + P ++ V + +SG PG Q Q P
Sbjct: 243 TLSEAGSTAGAAETRGAVEGAARTTPSRR------EITGVQAQPGEATSGPPGIQPGQEP 296
Query: 266 SAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREKTVT 325
PVTMIFMGYQN+EDE ETKKVLG +TI AELV+I++ E
Sbjct: 297 -----------PVTMIFMGYQNVEDEAETKKVLGLQDTITAELVVIEDAAEPK------- 338
Query: 326 DVSTIDGNAAELVSGRPVSDTTEPSSPEGKEESLATEPAPGTQKKKRCQCCVVM 379
+ + +G+AAE P ++ + E+ ++P KK RC+CC +M
Sbjct: 339 EPAPPNGSAAE-----PPTEAASREENQAGPEATTSDPQDLDMKKHRCKCCSIM 387
>gi|93141029 paralemmin isoform 2 [Homo sapiens]
Length = 343
Score = 188 bits (477), Expect = 8e-48
Identities = 133/389 (34%), Positives = 198/389 (50%), Gaps = 64/389 (16%)
Query: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAE 63
AE +ERLQAIAEKRKRQ EIE KR+QL+++ LQH KSK LRE+WLL+G P+ +E
Sbjct: 6 AETTSQQERLQAIAEKRKRQAEIENKRRQLEDERRQLQHLKSKALRERWLLEGTPSSASE 65
Query: 64 EEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLE-SEESQISAKEQIILEKLKETEKSFK 122
+E RRQ ++DE + + LED++ RLE+EI+ LE + + +AKE
Sbjct: 66 GDEDLRRQMQDDEQKTRLLEDSVSRLEKEIEVLERGDSAPATAKEN-------------- 111
Query: 123 DFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEG------VHQKGVKVYDDGT 176
++ V A + K+++ +T+++ S P G V ++ D
Sbjct: 112 ------AAAPSPVRAPAPSPAKEER--KTEVVMNSQQTPVGTPKDKRVSNTPLRTVDGSP 163
Query: 177 KVVYEVRSGGTVVENGVHKLSTKDVEELIQKAGQSSLG-----GGHVSERTVIADGSLSH 231
+ V + ENG+H LS+ +V+ELI KA + +L G R + + +
Sbjct: 164 MMKAVVHAVDGTAENGIHPLSSSEVDELIHKADEVTLSEAGSTAGAAETRGAVEGAARTT 223
Query: 232 PKEHMLCKEAKLEMVHKSRKDHSSGNPG-QQAQAPSAAGPEANLDQPVTMIFMGYQNIED 290
P ++ V + +SG PG Q Q P PVTMIFMGYQN+ED
Sbjct: 224 PSRR------EITGVQAQPGEATSGPPGIQPGQEP-----------PVTMIFMGYQNVED 266
Query: 291 EEETKKVLGYDETIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVSGRPVSDTTEPS 350
E ETKKVLG +TI AELV+I++ E + + +G+AAE P ++
Sbjct: 267 EAETKKVLGLQDTITAELVVIEDAAEPK-------EPAPPNGSAAE-----PPTEAASRE 314
Query: 351 SPEGKEESLATEPAPGTQKKKRCQCCVVM 379
+ E+ ++P KK RC+CC +M
Sbjct: 315 ENQAGPEATTSDPQDLDMKKHRCKCCSIM 343
>gi|8923243 palmdelphin [Homo sapiens]
Length = 551
Score = 158 bits (400), Expect = 7e-39
Identities = 98/250 (39%), Positives = 137/250 (54%), Gaps = 44/250 (17%)
Query: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
M EAEL K RLQAI +KRK Q EI KR +++E L QH K K LREKWLL GI +G
Sbjct: 1 MEEAELVKGRLQAITDKRKIQEEISQKRLKIEEDKLKHQHLKKKALREKWLLDGISSG-- 58
Query: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFK 122
+E+E ++Q+++D+ +++ LE +I RLE+EIQ LE E QIS KE+ IL+KLK E++ +
Sbjct: 59 KEQEEMKKQNQQDQHQIQVLEQSILRLEKEIQDLEKAELQISTKEEAILKKLKSIERTTE 118
Query: 123 DFQKGFS------------------------------------------STDGAVYAMEI 140
D + A+YAMEI
Sbjct: 119 DIIRSVKVEREERAEESIEDIYANIPDLPKSYIPSRLRKEINEEKEDDEQNRKALYAMEI 178
Query: 141 NVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVHKLSTKD 200
VEKD +TGE+ +LS+ + + G+KVYDDG K VY V S + NG L+ +
Sbjct: 179 KVEKDLKTGESTVLSSIPLPSDDFKGTGIKVYDDGQKSVYAVSSNHSAAYNGTDGLAPVE 238
Query: 201 VEELIQKAGQ 210
VEEL+++A +
Sbjct: 239 VEELLRQASE 248
Score = 61.2 bits (147), Expect = 1e-09
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 13/106 (12%)
Query: 220 ERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPS-------AAGPEA 272
E V+ D PK + +E + +H + +P Q + P+
Sbjct: 353 ESNVMQDKDAPSPKPRLSPRETIF-----GKSEHQNSSPTCQEDEEDVRYNIVHSLPPDI 407
Query: 273 NLDQPVTMIFMGYQNIEDEEETKKVL-GYDETIKAELVLIDEDDEK 317
N +PVTMIFMGYQ ED EE KK L GYD I AELV+ID+++E+
Sbjct: 408 NDTEPVTMIFMGYQQAEDSEEDKKFLTGYDGIIHAELVVIDDEEEE 453
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 71.2 bits (173), Expect = 1e-12
Identities = 38/100 (38%), Positives = 66/100 (66%), Gaps = 4/100 (4%)
Query: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPA--G 60
MAE+ L+++RL+ IAEKR+ Q EI R++++E+ L ++ K K LRE+WL+ G A
Sbjct: 1 MAESSLYRQRLEVIAEKRRLQEEIRAARREVEEEKLRVERLKRKSLRERWLMDGAAAVPE 60
Query: 61 TAEEEEARRRQSEED--EFRVKQLEDNIQRLEQEIQTLES 98
+E+ ++ QS E + R++ LED++ L+ ++Q L+S
Sbjct: 61 PSEDPTSKDPQSPEGQAQARIRNLEDSLFTLQSQLQLLQS 100
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 55.8 bits (133), Expect = 6e-08
Identities = 56/268 (20%), Positives = 121/268 (45%), Gaps = 20/268 (7%)
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
AE+ EA ++Q+EE R KQLED + ++++++ E E + S + EKL+ EK
Sbjct: 23 AEQAEAEQKQAEE---RSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKKA 79
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYE 181
D + +S + + +E +++ ++ T + +K + G KV+ E
Sbjct: 80 ADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEA------EKAADESERGMKVI-E 132
Query: 182 VRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEA 241
R+ + + ++ K+ + + ++A + V+ + VI +G L +E E+
Sbjct: 133 NRALKDEEKMELQEIQLKEAKHIAEEADRKY---EEVARKLVIIEGDLERTEERAELAES 189
Query: 242 KLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYD 301
K + + K+ ++ +AQA + E ++ + ++ + E ET+
Sbjct: 190 KCSELEEELKNVTNNLKSLEAQAEKYSQKEDKYEEEIKIL----TDKLKEAETRAEFAER 245
Query: 302 ETIKAELVLIDEDDE---KSLREKTVTD 326
K E + D +DE + L+ K +++
Sbjct: 246 SVAKLEKTIDDLEDELYAQKLKYKAISE 273
>gi|42476296 tropomyosin 2 (beta) isoform 1 [Homo sapiens]
Length = 284
Score = 55.8 bits (133), Expect = 6e-08
Identities = 57/261 (21%), Positives = 109/261 (41%), Gaps = 29/261 (11%)
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
AE+ EA ++Q+E+ R KQLE+ Q L+++++ E E + S + EKL++ EK
Sbjct: 22 AEQAEADKKQAED---RCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKA 78
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYE 181
D + +S + + +E +++ ++ T ++ ++ K E
Sbjct: 79 TDAEADVASLNRRIQLVEEELDRAQERLAT----------------ALQKLEEAEKAADE 122
Query: 182 VRSGGTVVENGVHK------LSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEH 235
G V+EN K L ++E A S V+ + VI +G L +E
Sbjct: 123 SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEER 182
Query: 236 MLCKEAKLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETK 295
E+K + + K ++ +AQA + E ++ + ++ + E ET+
Sbjct: 183 AEVAESKCGDLEEELKIVTNNLKSLEAQADKYSTKEDKYEEEIKLL----EEKLKEAETR 238
Query: 296 KVLGYDETIKAELVLIDEDDE 316
K E + D +DE
Sbjct: 239 AEFAERSVAKLEKTIDDLEDE 259
Score = 34.3 bits (77), Expect = 0.19
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 15/139 (10%)
Query: 22 RQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQ 81
R + E ++Q +++ L+ E+ LQ GT +E E +E + +++Q
Sbjct: 21 RAEQAEADKKQAEDRCKQLEE-------EQQALQKKLKGTEDEVEKYSESVKEAQEKLEQ 73
Query: 82 LED-------NIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGA 134
E ++ L + IQ +E E + + L+KL+E EK+ + ++G +
Sbjct: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
Query: 135 VYAMEINVE-KDKQTGETK 152
E +E ++ Q E K
Sbjct: 134 AMKDEEKMELQEMQLKEAK 152
>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
Length = 284
Score = 53.5 bits (127), Expect = 3e-07
Identities = 59/283 (20%), Positives = 113/283 (39%), Gaps = 30/283 (10%)
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
AE+ EA ++Q+E+ R KQLE+ Q L+++++ E E + S + EKL++ EK
Sbjct: 22 AEQAEADKKQAED---RCKQLEEEQQALQKKLKGTEDEVEKYSESVKEAQEKLEQAEKKA 78
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYE 181
D + +S + + +E +++ ++ T ++ ++ K E
Sbjct: 79 TDAEADVASLNRRIQLVEEELDRAQERLAT----------------ALQKLEEAEKAADE 122
Query: 182 VRSGGTVVENGVHK------LSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEH 235
G V+EN K L ++E A S V+ + VI +G L +E
Sbjct: 123 SERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYEEVARKLVILEGELERSEER 182
Query: 236 MLCKEAKLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETK 295
E++ + + + A + E ++ + ++ + E ET+
Sbjct: 183 AEVAESRARQLEEELRTMDQALKSLMASEEEYSTKEDKYEEEIKLL----EEKLKEAETR 238
Query: 296 KVLGYDETIKAELVLID-EDDEKSLREKTVTDVSTIDGNAAEL 337
K E + D E+ S +E+ V T+D EL
Sbjct: 239 AEFAERSVAKLEKTIDDLEETLASAKEENVEIHQTLDQTLLEL 281
Score = 34.3 bits (77), Expect = 0.19
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 15/139 (10%)
Query: 22 RQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVKQ 81
R + E ++Q +++ L+ E+ LQ GT +E E +E + +++Q
Sbjct: 21 RAEQAEADKKQAEDRCKQLEE-------EQQALQKKLKGTEDEVEKYSESVKEAQEKLEQ 73
Query: 82 LED-------NIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSSTDGA 134
E ++ L + IQ +E E + + L+KL+E EK+ + ++G +
Sbjct: 74 AEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENR 133
Query: 135 VYAMEINVE-KDKQTGETK 152
E +E ++ Q E K
Sbjct: 134 AMKDEEKMELQEMQLKEAK 152
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 50.4 bits (119), Expect = 3e-06
Identities = 39/163 (23%), Positives = 82/163 (50%), Gaps = 7/163 (4%)
Query: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
MA +E + +AEKR++ E +++ +EQ LQ + K +RE+ L + A
Sbjct: 590 MAGTTDREEATRLLAEKRRQARE----QREREEQERRLQAERDKRMREEQLAREAEARAE 645
Query: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEK-LKETEKSF 121
E EARRR+ +E + + ++ +RL+++ + E+ + + ++++ EK ++ E+
Sbjct: 646 REAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQER 705
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGV 164
++ +K E++ K KQ ++K + + PE V
Sbjct: 706 QERRKRLEEIMKRTRKSEVSETKQKQ--DSKEANANGSSPEPV 746
Score = 43.5 bits (101), Expect = 3e-04
Identities = 33/120 (27%), Positives = 59/120 (49%), Gaps = 10/120 (8%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
E E E + RLQA +KR R+ ++ + + E+ + + + REK
Sbjct: 612 EQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREK--------AQ 663
Query: 62 AEEEEARRRQSEEDEFRVKQLED-NIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
AE+EE R Q +++E + E+ QRLE+E + + +E + + + + E +K T KS
Sbjct: 664 AEQEEQERLQKQKEEAEARSREEAERQRLERE-KHFQQQEQERQERRKRLEEIMKRTRKS 722
Score = 30.4 bits (67), Expect = 2.7
Identities = 21/74 (28%), Positives = 37/74 (50%)
Query: 21 KRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEFRVK 80
K + E K + + L + K+K LREK L + + +A +R++ +E + +
Sbjct: 143 KERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQ 202
Query: 81 QLEDNIQRLEQEIQ 94
+LE N +R E IQ
Sbjct: 203 KLEKNKERYEAAIQ 216
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 50.1 bits (118), Expect = 3e-06
Identities = 54/268 (20%), Positives = 116/268 (43%), Gaps = 20/268 (7%)
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
AE+ EA ++ +E+ R KQLED + L+++++ E E + S + EKL+ EK
Sbjct: 22 AEQAEADKKAAED---RSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKA 78
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYE 181
D + +S + + +E +++ ++ T + +K + G KV+ E
Sbjct: 79 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA------EKAADESERGMKVI-E 131
Query: 182 VRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEA 241
R+ + + ++ K+ + + + A + V+ + VI + L +E E
Sbjct: 132 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKY---EEVARKLVIIESDLERAEERAELSEG 188
Query: 242 KLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYD 301
K + + K ++ +AQA + E ++ + ++ + E ET+
Sbjct: 189 KCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL----SDKLKEAETRAEFAER 244
Query: 302 ETIKAELVLIDEDDE---KSLREKTVTD 326
K E + D +DE + L+ K +++
Sbjct: 245 SVTKLEKSIDDLEDELYAQKLKYKAISE 272
Score = 35.4 bits (80), Expect = 0.085
Identities = 35/153 (22%), Positives = 68/153 (44%), Gaps = 21/153 (13%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEI-EGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
+M +L KE AE+ + + E + +QL+++++ LQ L+G
Sbjct: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKK----------LKGTEDE 56
Query: 61 TAEEEEARRRQSEEDEFRVKQLED---NIQRLEQEIQTLESEESQISAKEQIILEKLKET 117
+ EA + E+ E K+ D ++ L + IQ +E E + + L+KL+E
Sbjct: 57 LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
Query: 118 EKSFKDFQKGFSSTDGAVYAMEINVEKDKQTGE 150
EK+ + ++G +E +KD++ E
Sbjct: 117 EKAADESERGMK-------VIESRAQKDEEKME 142
Score = 28.9 bits (63), Expect = 8.0
Identities = 21/124 (16%), Positives = 52/124 (41%), Gaps = 2/124 (1%)
Query: 4 AEAELHKERLQAIAEKRKRQT--EIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
A+ + K +Q I K + + + K +++ ++++++ + L +G A
Sbjct: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
EE + + E + ++ R E+EI+ L + + + + + + EKS
Sbjct: 194 EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 253
Query: 122 KDFQ 125
D +
Sbjct: 254 DDLE 257
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 49.7 bits (117), Expect = 4e-06
Identities = 71/337 (21%), Positives = 145/337 (43%), Gaps = 41/337 (12%)
Query: 5 EAELHKER-LQAIAEKRKRQTEIEGKRQQLDEQILL----LQHSKSKVLREKWLLQGIPA 59
E + KE+ LQ + ++R+ T++E + +L +Q+ + + ++ + ++ L+ I
Sbjct: 741 EVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQ 800
Query: 60 GTAEEEEARR-------RQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILE 112
++EE ++ S+E + + ++L + IQ E+Q ++ E+ + + + +
Sbjct: 801 KLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKD 860
Query: 113 KLKETEKSFKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVY 172
KL + S K+ + F EK+ Q G+ IL E HQ V++
Sbjct: 861 KLSKVSDSLKNSKSEF--------------EKENQKGKAAILDLEKTCKELKHQLQVQM- 905
Query: 173 DDGTKVVYEVRSGGTVVENGVHKLS---TKDVEELIQKAGQSSLGGGHVSERTVIADGSL 229
++ K E++ + H+L E+LIQ Q++L E+ + G++
Sbjct: 906 ENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQ--AQNTLKQNEKEEQQL--QGNI 961
Query: 230 SHPKEHMLCKEAKLEMVHKSRK----DHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGY 285
+ K+ K+ ++E + K + Q Q AA A + ++++
Sbjct: 962 NELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVL---Q 1018
Query: 286 QNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLREK 322
N E +ET K L D + +L D KS+ EK
Sbjct: 1019 NNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEK 1055
Score = 32.3 bits (72), Expect = 0.72
Identities = 41/176 (23%), Positives = 74/176 (42%), Gaps = 28/176 (15%)
Query: 7 ELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHS----KSKVLREKWLLQGIPAGTA 62
EL +L++I K T ++ +Q L +Q L LQ K+ V +EK Q +
Sbjct: 1146 ELKSHKLESI----KEITNLKDAKQLLIQQKLELQGKADSLKAAVEQEKRNQQILKDQVK 1201
Query: 63 EEEEARRRQS-----------EEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIIL 111
+EEE +++ +E E +K+ E+N +L +I L + + Q
Sbjct: 1202 KEEEELKKEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQITALNENLGTVKKEWQSSQ 1261
Query: 112 EKLKETEKSFKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQK 167
++ E EK D + G + +E V+ ++ E + L + EG +K
Sbjct: 1262 RRVSELEKQTDDLR-------GEIAVLEATVQNNQD--ERRALLERCLKGEGEIEK 1308
Score = 32.0 bits (71), Expect = 0.94
Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 5/122 (4%)
Query: 3 MAEAELHKERLQAIAEKRKRQTEIEGKRQQ--LDEQILLLQHSKSKVLREKWLLQGIPAG 60
+ E L KE+ E++ + + K Q L ++ L Q +S++ + L I
Sbjct: 307 LTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQSRLSASETSLHRIHVE 366
Query: 61 TAEEEEARRRQSEE---DEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKET 117
+E+ EA ++ EE E + + L+ ++L+Q+ + E Q+ ++ + KL ET
Sbjct: 367 LSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLET 426
Query: 118 EK 119
E+
Sbjct: 427 ER 428
Score = 31.2 bits (69), Expect = 1.6
Identities = 24/105 (22%), Positives = 55/105 (52%), Gaps = 7/105 (6%)
Query: 22 RQTEIEGKRQQL---DEQILLLQH----SKSKVLREKWLLQGIPAGTAEEEEARRRQSEE 74
R++E+ RQ L +E++ L Q +++++ + L+Q + A E+ ++ ++
Sbjct: 1038 RESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQ 1097
Query: 75 DEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 119
+ R K L+D + + + L +E+S+++ E+I + KE K
Sbjct: 1098 LQERCKALQDIQKEKSLKEKELVNEKSKLAEIEEIKCRQEKEITK 1142
Score = 30.4 bits (67), Expect = 2.7
Identities = 45/222 (20%), Positives = 88/222 (39%), Gaps = 47/222 (21%)
Query: 1 MEMAEAELHK------ERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLL 54
+ +E LH+ E+ +A + ++ +E+E K Q L + LQ + +
Sbjct: 353 LSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREE-------- 404
Query: 55 QGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKL 114
+E+ + QSE ++ K LE Q L ++ + Q+ EKL
Sbjct: 405 --------KEQHGLQLQSEINQLHSKLLETERQ--------LGEAHGRLKEQRQLSSEKL 448
Query: 115 KETEKSFKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDD 174
+ E+ D Q S + + K+K T T+ L + HQ+ +
Sbjct: 449 MDKEQQVADLQLKLSRLEEQL--------KEKVTNSTE-LQHQLDKTKQQHQEQQALQQS 499
Query: 175 GTKVVYEVRSGGTVVENGVHKLSTKD-----VEELIQKAGQS 211
T + E ++ +E + ++ KD +E L+QK+ ++
Sbjct: 500 TTAKLREAQND---LEQVLRQIGDKDQKIQNLEALLQKSKEN 538
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 49.3 bits (116), Expect = 6e-06
Identities = 71/330 (21%), Positives = 144/330 (43%), Gaps = 33/330 (10%)
Query: 16 IAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEED 75
+A+ + E+E +++QL + + LL+ S K R + QG+ E + ++ E
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI----ENQRLQKTLENS 775
Query: 76 EFRVKQLEDNIQRLEQEIQTLES--EESQISAKEQIILEK---------------LKETE 118
+++QLE +Q LE E QTL+ EE +IS+K LEK K+ E
Sbjct: 776 NKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLE 835
Query: 119 KSFKDFQKGFSSTDGAVYAMEI---NVEKDKQT--GETKILSTSTIGPEGVHQKGVKVYD 173
K K ++ D + + N+EK+ +T E I S + + + ++ ++
Sbjct: 836 KENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVK 895
Query: 174 DGTKVVYEVRSGGTVVENGV-HKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHP 232
T ++++ T+ E+ V KL T+ + ++K G ER + + S
Sbjct: 896 RAT---IDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDS 952
Query: 233 KEHMLCKEAKLE-MVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDE 291
+ +L E+KLE + KS + +A+ + L Q + + Y+ ++
Sbjct: 953 RYKLL--ESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQR 1010
Query: 292 EETKKVLGYDETIKAELVLIDEDDEKSLRE 321
++ ++++ I E + + +++ RE
Sbjct: 1011 QDEERMVQSSPPISGEDNKWERESQETTRE 1040
Score = 37.7 bits (86), Expect = 0.017
Identities = 70/337 (20%), Positives = 137/337 (40%), Gaps = 44/337 (13%)
Query: 10 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 69
K+ L+ EK +R E+E + L+++ LLQ K+ K + I A E E
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQ---KKITNLKITCEKIEALEQENSEL-- 668
Query: 70 RQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQII---LEKLKETEKSFKDFQK 126
E + ++K+ D+ + L ++++LE E SQ+ + + +E LK Q
Sbjct: 669 ---ERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQL 725
Query: 127 GFSSTDGAVYAMEINVEKDKQT-GETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSG 185
+ ++ +E K + +T+ L S G + +Q+ K ++ K + ++ S
Sbjct: 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESE 785
Query: 186 GTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEM 245
+E L K++EEL I+ L ++ E +
Sbjct: 786 LQDLEMENQTLQ-KNLEEL------------------KISSKRLEQLEKENKSLEQETSQ 826
Query: 246 VHKSRKDHSSGNP--GQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEET-KKVLGYDE 302
+ K +K N QQA+ E N+ N+E E +T K +G +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNVK---------IGNLEKENKTLSKEIGIYK 877
Query: 303 TIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVS 339
L +++++++ ++ T+ D+ T+ +LVS
Sbjct: 878 ESCVRLKELEKENKELVKRATI-DIKTLVTLREDLVS 913
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 47.8 bits (112), Expect = 2e-05
Identities = 48/189 (25%), Positives = 86/189 (45%), Gaps = 18/189 (9%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEG--KRQQLDEQILLLQHSKSKVLREKWLLQGIPA 59
E E + ++R A AEK KR E G ++Q E+I + K + REK L +
Sbjct: 467 EEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERE-REKELEK---- 521
Query: 60 GTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKE-------QIILE 112
E+E+ R ++ E+D R ++ E +++ +++ + +E E Q KE + L+
Sbjct: 522 ---EQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQ 578
Query: 113 KLKETEKSFKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVY 172
K+KE EK + +K + + E N+E + E++ P Q +
Sbjct: 579 KMKEQEKEC-ELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSE 637
Query: 173 DDGTKVVYE 181
+ T VV+E
Sbjct: 638 KEATPVVHE 646
Score = 34.7 bits (78), Expect = 0.15
Identities = 31/143 (21%), Positives = 63/143 (44%), Gaps = 4/143 (2%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 64
E EL KE+ Q +R+++ E + +RQQ E+ L + K + + ++ + ++
Sbjct: 516 EKELEKEQEQ----EREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQK 571
Query: 65 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDF 124
E+ + Q +++ + +LE ++LE++I+ E + K++ KE E F
Sbjct: 572 EKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQ 631
Query: 125 QKGFSSTDGAVYAMEINVEKDKQ 147
S + E E Q
Sbjct: 632 DSNRSEKEATPVVHETEPESGSQ 654
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 47.4 bits (111), Expect = 2e-05
Identities = 55/277 (19%), Positives = 117/277 (42%), Gaps = 18/277 (6%)
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
AE+ EA ++ +E+ R KQLED + L+++++ E E + S + EKL+ EK
Sbjct: 22 AEQAEADKKAAED---RSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKKA 78
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYE 181
D + +S + + +E +++ ++ T + +K + G KV+ E
Sbjct: 79 TDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA------EKAADESERGMKVI-E 131
Query: 182 VRSGGTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEA 241
R+ + + ++ K+ + + + A + V+ + VI + L +E E
Sbjct: 132 SRAQKDEEKMEIQEIQLKEAKHIAEDADRKY---EEVARKLVIIESDLERAEERAELSEG 188
Query: 242 KLEMVHKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEETKKVLGYD 301
K + + K ++ +AQA + E ++ + ++ + E ET+
Sbjct: 189 KCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVL----SDKLKEAETRAEFAER 244
Query: 302 ETIKAELVLID-EDDEKSLREKTVTDVSTIDGNAAEL 337
K E + D E+ +E+ ++ +D EL
Sbjct: 245 SVTKLEKSIDDLEEKVAHAKEENLSMHQMLDQTLLEL 281
Score = 35.4 bits (80), Expect = 0.085
Identities = 35/153 (22%), Positives = 68/153 (44%), Gaps = 21/153 (13%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEI-EGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
+M +L KE AE+ + + E + +QL+++++ LQ L+G
Sbjct: 7 KMQMLKLDKENALDRAEQAEADKKAAEDRSKQLEDELVSLQKK----------LKGTEDE 56
Query: 61 TAEEEEARRRQSEEDEFRVKQLED---NIQRLEQEIQTLESEESQISAKEQIILEKLKET 117
+ EA + E+ E K+ D ++ L + IQ +E E + + L+KL+E
Sbjct: 57 LDKYSEALKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEA 116
Query: 118 EKSFKDFQKGFSSTDGAVYAMEINVEKDKQTGE 150
EK+ + ++G +E +KD++ E
Sbjct: 117 EKAADESERGMK-------VIESRAQKDEEKME 142
Score = 29.3 bits (64), Expect = 6.1
Identities = 21/125 (16%), Positives = 53/125 (42%), Gaps = 2/125 (1%)
Query: 4 AEAELHKERLQAIAEKRKRQT--EIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
A+ + K +Q I K + + + K +++ ++++++ + L +G A
Sbjct: 134 AQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAEL 193
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
EE + + E + ++ R E+EI+ L + + + + + + EKS
Sbjct: 194 EEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAERSVTKLEKSI 253
Query: 122 KDFQK 126
D ++
Sbjct: 254 DDLEE 258
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 47.0 bits (110), Expect = 3e-05
Identities = 38/139 (27%), Positives = 70/139 (50%), Gaps = 12/139 (8%)
Query: 16 IAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEED 75
+A+ + E+E +++QL + + LL+ S K R + QG+ E + ++ E
Sbjct: 720 MAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDI----ENQRLQKTLENS 775
Query: 76 EFRVKQLEDNIQRLEQEIQTLES--EESQISAKEQIILEKLKETEKSFKDFQKGFSSTDG 133
+++QLE +Q LE E QTL+ EE +IS+K +L++ EK K ++ S +
Sbjct: 776 NKKIQQLESELQDLEMENQTLQKNLEELKISSK------RLEQLEKENKSLEQETSQLEK 829
Query: 134 AVYAMEINVEKDKQTGETK 152
+E ++ +Q E K
Sbjct: 830 DKKQLEKENKRLRQQAEIK 848
Score = 37.7 bits (86), Expect = 0.017
Identities = 70/337 (20%), Positives = 137/337 (40%), Gaps = 44/337 (13%)
Query: 10 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 69
K+ L+ EK +R E+E + L+++ LLQ K+ K + I A E E
Sbjct: 614 KKELEHYKEKGERAEELENELHHLEKENELLQ---KKITNLKITCEKIEALEQENSEL-- 668
Query: 70 RQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQII---LEKLKETEKSFKDFQK 126
E + ++K+ D+ + L ++++LE E SQ+ + + +E LK Q
Sbjct: 669 ---ERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQL 725
Query: 127 GFSSTDGAVYAMEINVEKDKQT-GETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSG 185
+ ++ +E K + +T+ L S G + +Q+ K ++ K + ++ S
Sbjct: 726 ENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESE 785
Query: 186 GTVVENGVHKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEM 245
+E L K++EEL I+ L ++ E +
Sbjct: 786 LQDLEMENQTLQ-KNLEEL------------------KISSKRLEQLEKENKSLEQETSQ 826
Query: 246 VHKSRKDHSSGNP--GQQAQAPSAAGPEANLDQPVTMIFMGYQNIEDEEET-KKVLGYDE 302
+ K +K N QQA+ E N+ N+E E +T K +G +
Sbjct: 827 LEKDKKQLEKENKRLRQQAEIKDTTLEENNVK---------IGNLEKENKTLSKEIGIYK 877
Query: 303 TIKAELVLIDEDDEKSLREKTVTDVSTIDGNAAELVS 339
L +++++++ ++ T+ D+ T+ +LVS
Sbjct: 878 ESCVRLKELEKENKELVKRATI-DIKTLVTLREDLVS 913
Score = 37.4 bits (85), Expect = 0.022
Identities = 71/352 (20%), Positives = 143/352 (40%), Gaps = 68/352 (19%)
Query: 1 MEMAEAELHKERLQAIAE------KRKRQTEIEGKRQQLDEQIL--LLQHSKSKVLREKW 52
+E E E KE+L+ E K+ + E+ + ++ Q L L++S K+ + +
Sbjct: 725 LENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLES 784
Query: 53 LLQGIPAGTAEEEEARRRQSEEDEF---RVKQLEDNIQRLEQEIQTLESEESQISAKEQI 109
LQ + E + ++ EE + R++QLE + LEQE LE ++ Q+ + +
Sbjct: 785 ELQDLEM----ENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Query: 110 ILE--KLKETEKSFKDFQKGFSSTDGAVYAMEINVEKD-----------------KQTGE 150
+ + ++K+T + + G + + EI + K+ + T +
Sbjct: 841 LRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATID 900
Query: 151 TKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGVH-KLSTKDVEELIQKAG 209
K L T K ++ +D K+ +E+ G E +H + ST D +L++
Sbjct: 901 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKL 960
Query: 210 QSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDHSSGNPGQQAQAPSAAG 269
+S+L SL +E + EA+LE S N QQ
Sbjct: 961 ESTL------------KKSLEIKEEKIAALEARLE---------ESTNYNQQ-------- 991
Query: 270 PEANLDQPVTMIFMGYQNIEDEEETKKVLGYDETIKAELVLIDEDDEKSLRE 321
L Q + + Y+ ++ ++ ++++ I E + + +++ RE
Sbjct: 992 ----LRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRE 1039
>gi|239735592 TRAF2 and NCK interacting kinase isoform 8 [Homo
sapiens]
Length = 1268
Score = 46.6 bits (109), Expect = 4e-05
Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 6/141 (4%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
+E + E + + Q +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 373 LEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEE 429
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQ-TLESEESQISAKEQIILEKLKETEK 119
EE RRR E E++ KQLE+ QR + +Q L+ E + + + E+ +K
Sbjct: 430 QMRREEERRRAEHEQEYKRKQLEE--QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487
Query: 120 SFKDFQKGFSSTDGAVYAMEI 140
+++G S ++ +A EI
Sbjct: 488 PLYHYKEGMSPSEKPAWAKEI 508
>gi|239735590 TRAF2 and NCK interacting kinase isoform 7 [Homo
sapiens]
Length = 1276
Score = 46.6 bits (109), Expect = 4e-05
Identities = 37/141 (26%), Positives = 71/141 (50%), Gaps = 6/141 (4%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
+E + E + + Q +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 373 LEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEE 429
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQ-TLESEESQISAKEQIILEKLKETEK 119
EE RRR E E++ KQLE+ QR + +Q L+ E + + + E+ +K
Sbjct: 430 QMRREEERRRAEHEQEYKRKQLEE--QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487
Query: 120 SFKDFQKGFSSTDGAVYAMEI 140
+++G S ++ +A EI
Sbjct: 488 PLYHYKEGMSPSEKPAWAKEI 508
>gi|239735584 TRAF2 and NCK interacting kinase isoform 4 [Homo
sapiens]
Length = 1323
Score = 46.2 bits (108), Expect = 5e-05
Identities = 36/141 (25%), Positives = 71/141 (50%), Gaps = 6/141 (4%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
+E + E + + Q +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 373 LEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEE 429
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQ-TLESEESQISAKEQIILEKLKETEK 119
EE RRR E E++ KQLE+ QR + +Q L+ E + + + E+ +K
Sbjct: 430 QMRREEERRRAEHEQEYKRKQLEE--QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487
Query: 120 SFKDFQKGFSSTDGAVYAMEI 140
+++G S ++ +A E+
Sbjct: 488 PLYHYKEGMSPSEKPAWAKEV 508
>gi|239735582 TRAF2 and NCK interacting kinase isoform 3 [Homo
sapiens]
Length = 1331
Score = 46.2 bits (108), Expect = 5e-05
Identities = 36/141 (25%), Positives = 71/141 (50%), Gaps = 6/141 (4%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
+E + E + + Q +AE++KR E + +R++L+EQ + + + RE+ +
Sbjct: 373 LEQQQRENEEHKRQLLAERQKRIEEQKEQRRRLEEQQRREKELRKQQEREQ---RRHYEE 429
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQ-TLESEESQISAKEQIILEKLKETEK 119
EE RRR E E++ KQLE+ QR + +Q L+ E + + + E+ +K
Sbjct: 430 QMRREEERRRAEHEQEYKRKQLEE--QRQAERLQRQLKQERDYLVSLQHQRQEQRPVEKK 487
Query: 120 SFKDFQKGFSSTDGAVYAMEI 140
+++G S ++ +A E+
Sbjct: 488 PLYHYKEGMSPSEKPAWAKEV 508
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 46.2 bits (108), Expect = 5e-05
Identities = 38/120 (31%), Positives = 59/120 (49%), Gaps = 11/120 (9%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQIL-------LLQHSKSKVLREKWLLQGI 57
E L +ER + ++R+RQ + K QQ +EQ+L Q + K E+ L Q
Sbjct: 941 EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Query: 58 PAGTAEEEEARRRQSEEDEFRVK----QLEDNIQRLEQEIQTLESEESQISAKEQIILEK 113
EE E RRRQ E ++R K Q E+ + R E+E + L+ E Q +E++ E+
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEE 1060
Score = 40.0 bits (92), Expect = 0.003
Identities = 35/125 (28%), Positives = 64/125 (51%), Gaps = 19/125 (15%)
Query: 5 EAELHKERLQAIAEKR----KRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
E E ++RL+ E+R KR+ E E Q+ +Q L+ + + RE+WL
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQERRKQ--QLKRDQEEERRERWL------- 489
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEE---SQISAKEQIILEKLKET 117
EEE RR Q E E ++++ ++ +R EQ ++ E EE ++ +++Q+ E+ +
Sbjct: 490 -KLEEEERREQQERREQQLRREQE--ERREQRLKRQEEEERLQQRLRSEQQLRREQEERR 546
Query: 118 EKSFK 122
E+ K
Sbjct: 547 EQLLK 551
Score = 40.0 bits (92), Expect = 0.003
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 17/132 (12%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQIL-------LLQHSKSKVLREKWLLQGI 57
E L +ER + ++R+RQ E + QQ +EQ+L Q + + +E+ L Q
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 58 PAGTAEEEEARRRQSEE----DEFRVKQLEDNIQRLE------QEIQTLESEESQISAKE 107
EE E RRRQ E +E ++Q E+ + R E QE++ EE ++ +E
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEE 1150
Query: 108 QIILEKLKETEK 119
+ +L + E +
Sbjct: 1151 EQLLREEPEKRR 1162
Score = 39.3 bits (90), Expect = 0.006
Identities = 30/110 (27%), Positives = 56/110 (50%), Gaps = 4/110 (3%)
Query: 2 EMAEAELHKERLQAIAEKR-KRQTEIEGKRQQL--DEQILLLQHSKSKVLREKWLLQGIP 58
E E L +E + E+R KR+ E E + Q+L +EQ + KS++ + +W L+
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLES-E 711
Query: 59 AGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQ 108
A + + R + +E + R ++ E+ +R E E+Q E E + +E+
Sbjct: 712 ADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Score = 39.3 bits (90), Expect = 0.006
Identities = 49/202 (24%), Positives = 87/202 (43%), Gaps = 29/202 (14%)
Query: 3 MAEAELHKERLQAIAEKRKRQT---EIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPA 59
+ E +L ER + +++R E E RQ+ +EQ L Q S K E+ L Q
Sbjct: 1750 LEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQ---- 1805
Query: 60 GTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 119
EE+ R Q + ++R + E+ +Q EQE + + + Q A+EQ + EK
Sbjct: 1806 --EREEQQLRPQQRDGKYRWE--EEQLQLEEQEQRLRQERDRQYRAEEQFATQ-----EK 1856
Query: 120 SFKDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVV 179
S ++ Q+ + + +K +Q E K+ + Q+ +V G
Sbjct: 1857 SRREEQELWQEEE----------QKRRQERERKLREEHIRRQQKEEQRHRQV---GEIKS 1903
Query: 180 YEVRSGGTVVENGVHKLSTKDV 201
E + G ++E G H+ ++ V
Sbjct: 1904 QEGKGHGRLLEPGTHQFASVPV 1925
Score = 38.9 bits (89), Expect = 0.008
Identities = 34/117 (29%), Positives = 57/117 (48%), Gaps = 17/117 (14%)
Query: 10 KERLQAIAEKRKRQTEIEGK-------RQQLDEQILLLQHSKSKVLREKWLLQGIPAGTA 62
+ER E++ R+ E+E K RQ+ +++ L Q K+L E+ L
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRP------E 1758
Query: 63 EEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 119
EE+ RRQ + +FR E+ R E+E Q L S+ES +E+ L + +E ++
Sbjct: 1759 REEQQLRRQERDRKFR----EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811
Score = 38.5 bits (88), Expect = 0.010
Identities = 35/127 (27%), Positives = 65/127 (51%), Gaps = 16/127 (12%)
Query: 5 EAELHKERLQAIAEK--------RKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQG 56
E EL +E Q + E+ R+RQ E + QQ +EQ LL+ + K R++ Q
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ--LLREEREKRRRQELERQY 1140
Query: 57 IPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKE 116
++EE + + E ++ R ++LE R +E + L+ EE Q+ +EQ ++ +E
Sbjct: 1141 REEEEVQQEEEQLLREEPEKRRRQELE----RQYREEEELQQEEEQLLREEQ--EKRRQE 1194
Query: 117 TEKSFKD 123
E+ +++
Sbjct: 1195 RERQYRE 1201
Score = 37.7 bits (86), Expect = 0.017
Identities = 27/107 (25%), Positives = 55/107 (51%), Gaps = 6/107 (5%)
Query: 18 EKRKRQTEIEGKRQQLD---EQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEE 74
EKR+RQ + R++ + E+ LL+ + K R++W Q ++EE + + E
Sbjct: 979 EKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 75 DEFRVKQLEDNI---QRLEQEIQTLESEESQISAKEQIILEKLKETE 118
++ R+++ E + L+QE + L EE + ++++ + KE E
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Score = 36.6 bits (83), Expect = 0.038
Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 10/122 (8%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGK--------RQQLDEQILLLQHSKSKVLREKWLLQG 56
E L KE + E+ +RQ E++ + RQ+L + + + ++ RE+ L +
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309
Query: 57 IPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQE--IQTLESEESQISAKEQIILEKL 114
E++E RR Q E E + ++ E ++R ++E Q L E+ + ++Q+ E+
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369
Query: 115 KE 116
+E
Sbjct: 370 EE 371
Score = 36.6 bits (83), Expect = 0.038
Identities = 34/145 (23%), Positives = 68/145 (46%), Gaps = 14/145 (9%)
Query: 10 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 69
+ER + E+ R E E K + +EQ L Q + K L+E+ L+ G ++ R
Sbjct: 1497 QERDRKFREQELRSQEPERKFLE-EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 70 RQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFS 129
+ EE++ R ++ E + R E++ + EE ++ +EQ E+ F + ++
Sbjct: 1556 KFREEEQLRQEREEQQLSRQERD-RKFRLEEQKVRRQEQ---------ERKFMEDEQQLR 1605
Query: 130 STDGAVYAMEINVEKDKQTGETKIL 154
+G ++ E+D++ E + L
Sbjct: 1606 RQEG---QQQLRQERDRKFREDEQL 1627
Score = 36.2 bits (82), Expect = 0.050
Identities = 29/109 (26%), Positives = 61/109 (55%), Gaps = 6/109 (5%)
Query: 12 RLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREK-WLLQGIPAGTAEEEEARRR 70
R + + E R++ E E ++Q+ + Q + Q + K R++ +L+ EEE R+R
Sbjct: 211 RRRELLELRRKGRE-EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 71 QSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 119
+ +E+E ++++LE Q L +E Q E ++ ++ ++Q L + +E E+
Sbjct: 270 ELQEEEEQLRKLER--QELRRERQEEEQQQQRLRREQQ--LRRKQEEER 314
Score = 36.2 bits (82), Expect = 0.050
Identities = 32/120 (26%), Positives = 59/120 (49%), Gaps = 6/120 (5%)
Query: 5 EAELHKERLQAIAEKRKRQ----TEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
E E ++RL+ E+R Q E+E + +Q + + L+ + + R + LL+
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVE-RLEQEERREQRLKREEPEEERRQQLLKSEEQE 640
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
+++ RR Q E E R+K+ E+ +RLEQ ++ EE + + E+ +E KS
Sbjct: 641 ERRQQQLRREQQERREQRLKR-EEEEERLEQRLKREHEEERREQELAEEEQEQARERIKS 699
Score = 36.2 bits (82), Expect = 0.050
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 18 EKRKRQT------EIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQ 71
EKR+RQ E E Q+ +EQ L Q K E+ Q EEE+ RRQ
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ 1386
Query: 72 SEEDEFRVKQLEDNIQRLEQEI-----QTLESEESQISAKEQIILEKLKETEKSFK 122
E +F ++ + Q EQ++ + EE Q+S +E+ K +E E+ +
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD--RKFREEEQQVR 1440
Score = 35.0 bits (79), Expect = 0.11
Identities = 35/123 (28%), Positives = 58/123 (47%), Gaps = 18/123 (14%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQ--------QLDEQILLLQHSK------SKVLRE 50
E EL +E Q + E+R+++ E +RQ Q +EQ+L + K + RE
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE 1172
Query: 51 KWLLQGIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQII 110
+ LQ EE+ +RRQ E ++R E+ +QR +++ Q E+ + K Q
Sbjct: 1173 EEELQQEEEQLLREEQEKRRQERERQYRE---EEELQRQKRK-QRYRDEDQRSDLKWQWE 1228
Query: 111 LEK 113
EK
Sbjct: 1229 PEK 1231
Score = 35.0 bits (79), Expect = 0.11
Identities = 33/166 (19%), Positives = 74/166 (44%), Gaps = 32/166 (19%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
E E +LH++ +++ + E + +RQ+ ++Q L+H + + RE
Sbjct: 1630 EREEQQLHRQE----RDRKFLEEEPQLRRQEREQQ---LRHDRDRKFRE----------- 1671
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
EE ++ EE + R ++ + + EQ+++ E E + ++Q+ + +E E+ F
Sbjct: 1672 ---EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL---RRQELERKF 1725
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPEGVHQK 167
++ ++ T+ + +Q KIL + PE Q+
Sbjct: 1726 REEEQLRQETE--------QEQLRRQERYRKILEEEQLRPEREEQQ 1763
Score = 34.7 bits (78), Expect = 0.15
Identities = 26/104 (25%), Positives = 55/104 (52%), Gaps = 9/104 (8%)
Query: 10 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 69
+ER + E+ ++ E +R+ L+E+ L Q K E+ LLQ EE++ R
Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ-----EREEQQLHR 1480
Query: 70 RQSE----EDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQI 109
++ + E+E ++++ E + + EQE+++ E E + ++Q+
Sbjct: 1481 QERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Score = 33.5 bits (75), Expect = 0.32
Identities = 28/123 (22%), Positives = 59/123 (47%), Gaps = 10/123 (8%)
Query: 7 ELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEE 66
E + R Q + + +++ E E + Q+L + + + ++L+ + + +EE
Sbjct: 541 EQEERREQLLKREEEKRLEQERREQRLKRE---QEERRDQLLKREEERRQQRLKREQEER 597
Query: 67 ARRRQSEEDEFRVKQLEDNIQRLEQE-------IQTLESEESQISAKEQIILEKLKETEK 119
+R E+ R++Q E QRL++E Q L+SEE + ++Q+ E+ + E+
Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQ 657
Query: 120 SFK 122
K
Sbjct: 658 RLK 660
Score = 33.5 bits (75), Expect = 0.32
Identities = 34/149 (22%), Positives = 69/149 (46%), Gaps = 26/149 (17%)
Query: 5 EAELHKERLQA---IAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
++E ++RL A + E+R+RQ E +RQQ +++ L P
Sbjct: 776 KSERGRQRLSARPPLREQRERQLRAE-ERQQREQRFL-------------------PEEE 815
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK-- 119
+E+ R+R+ E E + + E+ +QR E+ Q E E+ +E+ ++ + +K
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWR 875
Query: 120 -SFKDFQKGFSSTDGAVYAMEINVEKDKQ 147
++ +K T A A++ + K++Q
Sbjct: 876 WQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Score = 33.1 bits (74), Expect = 0.42
Identities = 31/127 (24%), Positives = 65/127 (51%), Gaps = 16/127 (12%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 64
E +L +++ + E+++ + E + +R+Q +E+ + + RE+ L + E+
Sbjct: 303 EQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR-------EQ 355
Query: 65 EEARR----RQSEEDEFRVKQLEDNIQ-RLEQEIQTLESEESQISAKEQIILEKLKETEK 119
EE RR R+ +E+E R +QL Q R EQ+++ E Q+ ++Q+ E+ E+
Sbjct: 356 EEERREQQLRREQEEERREQQLRREQQLRREQQLR----REQQLRREQQLRREQQLRREQ 411
Query: 120 SFKDFQK 126
+ Q+
Sbjct: 412 QLRREQQ 418
Score = 33.1 bits (74), Expect = 0.42
Identities = 32/121 (26%), Positives = 63/121 (52%), Gaps = 16/121 (13%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
++ E EL +E EKR+RQ E +RQ +E+ LQ + ++LRE+ +
Sbjct: 906 LQEEEEELQREE----REKRRRQ---EQERQYREEE--QLQQEEEQLLREEREKR----- 951
Query: 61 TAEEEEARRRQSEEDEFRVKQL--EDNIQRLEQEIQTLESEESQISAKEQIILEKLKETE 118
+E E + R+ ++ + + +QL E+ +R QE + EE ++ +E+ +L + +E
Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011
Query: 119 K 119
+
Sbjct: 1012 R 1012
Score = 32.7 bits (73), Expect = 0.55
Identities = 33/140 (23%), Positives = 68/140 (48%), Gaps = 26/140 (18%)
Query: 10 KERLQAIAEKRKRQTEIEGK--RQQLDEQILLLQHS-------KSKVLREKWLLQGIPAG 60
++ LQ E+R+ Q + + R QL+E+ +H+ + ++ +E+ LLQ
Sbjct: 853 EDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE 912
Query: 61 TAEEEEARRRQSEE-----DEFRVKQLEDNIQRLEQEIQTLESEESQ------ISAKEQI 109
EE +RR+ E+ +E +++Q E+ + R E+E + + E Q + KE+
Sbjct: 913 LQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ 972
Query: 110 IL------EKLKETEKSFKD 123
+L + +E EK +++
Sbjct: 973 LLGEEPEKRRRQEREKKYRE 992
Score = 32.7 bits (73), Expect = 0.55
Identities = 32/119 (26%), Positives = 54/119 (45%), Gaps = 16/119 (13%)
Query: 10 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVL----------REKWLLQGIPA 59
+ER + E+ R E +G++ +EQ L Q + K L RE+ L Q
Sbjct: 1356 QERDRKFREEELRHQE-QGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 60 GTAEEEEARRRQSEEDEFR-----VKQLEDNIQRLEQEIQTLESEESQISAKEQIILEK 113
EEE+ RQ + +FR V++ E + LE+E Q + + +EQ++ E+
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER 1473
Score = 32.3 bits (72), Expect = 0.72
Identities = 33/124 (26%), Positives = 60/124 (48%), Gaps = 13/124 (10%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
E+AE E E+ + + ++ +++ + E RQ+ + Q + + E+ LQ
Sbjct: 147 ELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQ------EREERRAEEEQLQSCKGHE 200
Query: 62 AEE--EEARRRQSEEDEFRVKQLEDNIQ-RLEQEIQTLESEESQISAKEQIIL----EKL 114
EE +E + R+ E E R K E+ Q R E++ + + EE + K + +L EKL
Sbjct: 201 TEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKL 260
Query: 115 KETE 118
+E E
Sbjct: 261 QEEE 264
Score = 32.3 bits (72), Expect = 0.72
Identities = 29/123 (23%), Positives = 55/123 (44%), Gaps = 5/123 (4%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLRE-----KWLLQG 56
E E + R Q + +++ + E KRQ+ +E++ S+ ++ RE + LL+
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 57 IPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKE 116
E+E +R E E R QL + Q+ E EE ++ +E+L++
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ 612
Query: 117 TEK 119
E+
Sbjct: 613 EER 615
Score = 32.0 bits (71), Expect = 0.94
Identities = 28/119 (23%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 64
E +L +E+ ++ +R+ E E Q+ +++ + + + R WL + E+
Sbjct: 410 EQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQ 469
Query: 65 E----EARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 119
E + +R Q EE R +LE+ +R +QE + + Q +EQ L++ +E E+
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ-RLKRQEEEER 527
Score = 31.6 bits (70), Expect = 1.2
Identities = 31/111 (27%), Positives = 60/111 (54%), Gaps = 13/111 (11%)
Query: 18 EKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR----RQ-S 72
E++ R+ E E K Q +EQ L Q + K E+ L Q E+E+ RR R+
Sbjct: 1697 EQQLRRQERERKFLQ-EEQQLRRQELERKFREEEQLRQ-----ETEQEQLRRQERYRKIL 1750
Query: 73 EEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKD 123
EE++ R ++ E ++R E++ + E E+ + +EQ + + +E+++ F++
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQL--RSQESDRKFRE 1799
Score = 31.2 bits (69), Expect = 1.6
Identities = 30/127 (23%), Positives = 59/127 (46%), Gaps = 11/127 (8%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
E E + + Q E+++ + E + +R+Q + + L+ + + RE+ L +
Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR------ 366
Query: 62 AEEEEARRRQS--EEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEK 119
E+EE RR Q E + R +Q Q+L +E Q E Q+ ++Q+ E+ E+
Sbjct: 367 -EQEEERREQQLRREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRREQ 423
Query: 120 SFKDFQK 126
+ Q+
Sbjct: 424 QLRREQE 430
Score = 31.2 bits (69), Expect = 1.6
Identities = 25/120 (20%), Positives = 58/120 (48%), Gaps = 7/120 (5%)
Query: 10 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 69
++R + E++ R+ E E K + DEQ L Q + ++ +E+ +E E ++
Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFME-DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQ 1635
Query: 70 RQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILE------KLKETEKSFKD 123
+E + + + E ++R E+E Q + + +EQ++ E + +E ++ F++
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFRE 1695
Score = 30.4 bits (67), Expect = 2.7
Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 22/115 (19%)
Query: 10 KERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR 69
+E+LQ ++ Q E +G ++ + + S+ + +KW Q EEE RR
Sbjct: 837 EEQLQRRERAQQLQEEEDGLQEDQERR-----RSQEQRRDQKWRWQ------LEEERKRR 885
Query: 70 R-----------QSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEK 113
R Q +++ +++ E+ +QR E+E + + +E Q +EQ+ E+
Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940
Score = 30.0 bits (66), Expect = 3.6
Identities = 33/131 (25%), Positives = 61/131 (46%), Gaps = 11/131 (8%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKR---QQLDEQILLLQHSKSKVLREKWLLQGI 57
+E E +ER Q + E+ E + +R +Q +Q Q + + R L
Sbjct: 834 LEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLY--- 890
Query: 58 PAGTAEEEEARRRQS---EEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKL 114
A A +E+ R+ Q EE+E ++ + +R EQE Q E E+ Q +EQ++ E+
Sbjct: 891 -AKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ-QEEEQLLREER 948
Query: 115 KETEKSFKDFQ 125
++ + ++ Q
Sbjct: 949 EKRRRQERERQ 959
Score = 29.6 bits (65), Expect = 4.7
Identities = 25/110 (22%), Positives = 55/110 (50%), Gaps = 18/110 (16%)
Query: 18 EKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRRQSEEDEF 77
E RKR+T + + ++L E+ + + + L+E EEE+ R+ + +E
Sbjct: 245 EWRKRETVLRKEEEKLQEE----EPQRQRELQE------------EEEQLRKLERQELRR 288
Query: 78 RVKQLEDNIQRL--EQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQ 125
++ E QRL EQ+++ + EE + +E+ ++ +E ++ ++ Q
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Score = 29.6 bits (65), Expect = 4.7
Identities = 30/127 (23%), Positives = 56/127 (44%), Gaps = 14/127 (11%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEGKRQQL------DEQILLLQHSKSKVLREKWLLQ 55
++ + + ++ + E+++R E E +R Q +E+ L + K R++ +
Sbjct: 1257 QLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE 1316
Query: 56 GIPAGTAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLK 115
E EE RRRQ + +FR E+ E+E Q L +E +E E+L+
Sbjct: 1317 EKQLLREEREEKRRRQETDRKFR----EEEQLLQEREEQPLRRQERDRKFRE----EELR 1368
Query: 116 ETEKSFK 122
E+ K
Sbjct: 1369 HQEQGRK 1375
Score = 29.3 bits (64), Expect = 6.1
Identities = 28/115 (24%), Positives = 51/115 (44%), Gaps = 14/115 (12%)
Query: 2 EMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGT 61
E ++ + K + Q +E RQ+++ + ++ + Q + + + RE L
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQW------ 748
Query: 62 AEEEEARRRQSEEDEFR--------VKQLEDNIQRLEQEIQTLESEESQISAKEQ 108
EEE A R+Q EE++ R ++ E QRL E E Q+ A+E+
Sbjct: 749 QEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Score = 28.9 bits (63), Expect = 8.0
Identities = 25/128 (19%), Positives = 65/128 (50%), Gaps = 5/128 (3%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEE 64
+ E +++L+ E+ +R+ ++ +R+Q +E+ + ++ RE+ L + E
Sbjct: 343 QEERREQQLRREQEEERREQQL--RREQEEERREQQLRREQQLRREQQLRR--EQQLRRE 398
Query: 65 EEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDF 124
++ RR Q E ++++ E ++R +Q + E E + +++ ++LK ++ +D+
Sbjct: 399 QQLRREQQLRREQQLRR-EQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457
Query: 125 QKGFSSTD 132
K T+
Sbjct: 458 LKREEETE 465
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 45.8 bits (107), Expect = 6e-05
Identities = 43/161 (26%), Positives = 82/161 (50%), Gaps = 22/161 (13%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKV---LREKWLLQGIPAGT 61
E L ++R Q IA +R+R+ E +RQQ +E + L+ + + +++ LL+
Sbjct: 785 EEALRRQREQEIALRRQREEE---ERQQQEEALRRLEERRREEEERRKQEELLR------ 835
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
+EEEA + EE+E + ++LE+N R+E+E L EE + KE + +++ KE +
Sbjct: 836 KQEEEAAKWAREEEEAQ-RRLEENRLRMEEEAARLRHEEEERKRKE-LEVQRQKELMRQR 893
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPE 162
+ Q+ ++ +Q + K+ S+ST G +
Sbjct: 894 QQQQEALRRLQ--------QQQQQQQLAQMKLPSSSTWGQQ 926
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 20/121 (16%)
Query: 6 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEE 65
A+L +ER +A E R ++ E E KRQ+ L+ + ++LR ++E
Sbjct: 729 AKLEQERREA--EMRAKREEEERKRQEE------LRRQQEEILRR------------QQE 768
Query: 66 EARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQ 125
E R+R+ EE+ R KQ E ++ EQEI E + +++ L +L+E + ++ +
Sbjct: 769 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 828
Query: 126 K 126
K
Sbjct: 829 K 829
Score = 33.9 bits (76), Expect = 0.25
Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 35 EQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR---RQSEEDEFRVKQLEDNIQRLEQ 91
EQ+ L+ +K+ L ++ + A EEE R+ R+ +E+ R +Q E+ +R E+
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 777
Query: 92 EIQTLESEESQISAKEQ-IILEKLKETEK 119
E+ + EE+ +EQ I L + +E E+
Sbjct: 778 ELARRKQEEALRRQREQEIALRRQREEEE 806
Score = 32.3 bits (72), Expect = 0.72
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Query: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLR-EKWLLQGIPAGTA 62
++A L +Q + E+R+RQ E +RQQ + L Q + + + W P+GT
Sbjct: 934 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 993
Query: 63 ------EEEEARRRQSEEDE 76
++EEAR+ Q ++ +
Sbjct: 994 KSLLEIQQEEARQMQKQQQQ 1013
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 45.8 bits (107), Expect = 6e-05
Identities = 43/161 (26%), Positives = 82/161 (50%), Gaps = 22/161 (13%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKV---LREKWLLQGIPAGT 61
E L ++R Q IA +R+R+ E +RQQ +E + L+ + + +++ LL+
Sbjct: 812 EEALRRQREQEIALRRQREEE---ERQQQEEALRRLEERRREEEERRKQEELLR------ 862
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
+EEEA + EE+E + ++LE+N R+E+E L EE + KE + +++ KE +
Sbjct: 863 KQEEEAAKWAREEEEAQ-RRLEENRLRMEEEAARLRHEEEERKRKE-LEVQRQKELMRQR 920
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPE 162
+ Q+ ++ +Q + K+ S+ST G +
Sbjct: 921 QQQQEALRRLQ--------QQQQQQQLAQMKLPSSSTWGQQ 953
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 20/121 (16%)
Query: 6 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEE 65
A+L +ER +A E R ++ E E KRQ+ L+ + ++LR ++E
Sbjct: 756 AKLEQERREA--EMRAKREEEERKRQEE------LRRQQEEILRR------------QQE 795
Query: 66 EARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQ 125
E R+R+ EE+ R KQ E ++ EQEI E + +++ L +L+E + ++ +
Sbjct: 796 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 855
Query: 126 K 126
K
Sbjct: 856 K 856
Score = 33.9 bits (76), Expect = 0.25
Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 35 EQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR---RQSEEDEFRVKQLEDNIQRLEQ 91
EQ+ L+ +K+ L ++ + A EEE R+ R+ +E+ R +Q E+ +R E+
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 804
Query: 92 EIQTLESEESQISAKEQ-IILEKLKETEK 119
E+ + EE+ +EQ I L + +E E+
Sbjct: 805 ELARRKQEEALRRQREQEIALRRQREEEE 833
Score = 32.3 bits (72), Expect = 0.72
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Query: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLR-EKWLLQGIPAGTA 62
++A L +Q + E+R+RQ E +RQQ + L Q + + + W P+GT
Sbjct: 961 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 1020
Query: 63 ------EEEEARRRQSEEDE 76
++EEAR+ Q ++ +
Sbjct: 1021 KSLLEIQQEEARQMQKQQQQ 1040
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.8 bits (107), Expect = 6e-05
Identities = 43/161 (26%), Positives = 82/161 (50%), Gaps = 22/161 (13%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKV---LREKWLLQGIPAGT 61
E L ++R Q IA +R+R+ E +RQQ +E + L+ + + +++ LL+
Sbjct: 791 EEALRRQREQEIALRRQREEE---ERQQQEEALRRLEERRREEEERRKQEELLR------ 841
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
+EEEA + EE+E + ++LE+N R+E+E L EE + KE + +++ KE +
Sbjct: 842 KQEEEAAKWAREEEEAQ-RRLEENRLRMEEEAARLRHEEEERKRKE-LEVQRQKELMRQR 899
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPE 162
+ Q+ ++ +Q + K+ S+ST G +
Sbjct: 900 QQQQEALRRLQ--------QQQQQQQLAQMKLPSSSTWGQQ 932
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 20/121 (16%)
Query: 6 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEE 65
A+L +ER +A E R ++ E E KRQ+ L+ + ++LR ++E
Sbjct: 735 AKLEQERREA--EMRAKREEEERKRQEE------LRRQQEEILRR------------QQE 774
Query: 66 EARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQ 125
E R+R+ EE+ R KQ E ++ EQEI E + +++ L +L+E + ++ +
Sbjct: 775 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 834
Query: 126 K 126
K
Sbjct: 835 K 835
Score = 33.9 bits (76), Expect = 0.25
Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 35 EQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR---RQSEEDEFRVKQLEDNIQRLEQ 91
EQ+ L+ +K+ L ++ + A EEE R+ R+ +E+ R +Q E+ +R E+
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 92 EIQTLESEESQISAKEQ-IILEKLKETEK 119
E+ + EE+ +EQ I L + +E E+
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEE 812
Score = 32.3 bits (72), Expect = 0.72
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Query: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLR-EKWLLQGIPAGTA 62
++A L +Q + E+R+RQ E +RQQ + L Q + + + W P+GT
Sbjct: 940 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 999
Query: 63 ------EEEEARRRQSEEDE 76
++EEAR+ Q ++ +
Sbjct: 1000 KSLLEIQQEEARQMQKQQQQ 1019
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.8 bits (107), Expect = 6e-05
Identities = 43/161 (26%), Positives = 82/161 (50%), Gaps = 22/161 (13%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKV---LREKWLLQGIPAGT 61
E L ++R Q IA +R+R+ E +RQQ +E + L+ + + +++ LL+
Sbjct: 791 EEALRRQREQEIALRRQREEE---ERQQQEEALRRLEERRREEEERRKQEELLR------ 841
Query: 62 AEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSF 121
+EEEA + EE+E + ++LE+N R+E+E L EE + KE + +++ KE +
Sbjct: 842 KQEEEAAKWAREEEEAQ-RRLEENRLRMEEEAARLRHEEEERKRKE-LEVQRQKELMRQR 899
Query: 122 KDFQKGFSSTDGAVYAMEINVEKDKQTGETKILSTSTIGPE 162
+ Q+ ++ +Q + K+ S+ST G +
Sbjct: 900 QQQQEALRRLQ--------QQQQQQQLAQMKLPSSSTWGQQ 932
Score = 41.6 bits (96), Expect = 0.001
Identities = 34/121 (28%), Positives = 61/121 (50%), Gaps = 20/121 (16%)
Query: 6 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEE 65
A+L +ER +A E R ++ E E KRQ+ L+ + ++LR ++E
Sbjct: 735 AKLEQERREA--EMRAKREEEERKRQEE------LRRQQEEILRR------------QQE 774
Query: 66 EARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQ 125
E R+R+ EE+ R KQ E ++ EQEI E + +++ L +L+E + ++ +
Sbjct: 775 EERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERR 834
Query: 126 K 126
K
Sbjct: 835 K 835
Score = 33.9 bits (76), Expect = 0.25
Identities = 26/89 (29%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 35 EQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARR---RQSEEDEFRVKQLEDNIQRLEQ 91
EQ+ L+ +K+ L ++ + A EEE R+ R+ +E+ R +Q E+ +R E+
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEE 783
Query: 92 EIQTLESEESQISAKEQ-IILEKLKETEK 119
E+ + EE+ +EQ I L + +E E+
Sbjct: 784 ELARRKQEEALRRQREQEIALRRQREEEE 812
Score = 32.3 bits (72), Expect = 0.72
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 7/80 (8%)
Query: 4 AEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLR-EKWLLQGIPAGTA 62
++A L +Q + E+R+RQ E +RQQ + L Q + + + W P+GT
Sbjct: 940 SQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTT 999
Query: 63 ------EEEEARRRQSEEDE 76
++EEAR+ Q ++ +
Sbjct: 1000 KSLLEIQQEEARQMQKQQQQ 1019
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 25/200 (12%)
Query: 2 EMAEAELHKERLQAIA-EKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
E+ + +LH E Q E K+Q + + Q E+ + + K+ REK +L
Sbjct: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA---- 1493
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
E + ++Q EE + + + LE E+Q + S+ES+ A + ++L++ E
Sbjct: 1494 ---EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
Query: 121 FKDFQKGFSSTDGAV-------YAMEINVEKDKQTGETKILSTSTIGPEGVH--QKGVK- 170
KD ++ G + +E+ +E+ +QT ++ S E QK +K
Sbjct: 1551 VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ 1610
Query: 171 -------VYDDGTKVVYEVR 183
Y+D KV+ E R
Sbjct: 1611 MEVQLEEEYEDKQKVLREKR 1630
Score = 33.5 bits (75), Expect = 0.32
Identities = 38/137 (27%), Positives = 59/137 (43%), Gaps = 23/137 (16%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQ-------QLDEQILLLQHSKSKVLREKWLLQGI 57
E E+ + R E R E+E RQ Q++ Q+ K KVLREK L+G
Sbjct: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
Query: 58 PAGTAEEEEARRRQSE----EDEFRVKQLEDNIQRL----------EQEIQTLES--EES 101
A +++ R +SE +D R K L + Q + ++EI L++ EES
Sbjct: 1636 LATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEES 1695
Query: 102 QISAKEQIILEKLKETE 118
+ + + K E E
Sbjct: 1696 EFTCAAAVKARKAMEVE 1712
Score = 32.0 bits (71), Expect = 0.94
Identities = 64/300 (21%), Positives = 114/300 (38%), Gaps = 55/300 (18%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLRE-----KWLLQ 55
ME+ E ++++ + + EKR E+EGK L +Q+ K LR+ K LL
Sbjct: 1611 MEVQLEEEYEDKQKVLREKR----ELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLA 1666
Query: 56 GIP---------AGTAEEEEARRRQSEEDEFRV-------KQLEDNIQRLEQEIQ----- 94
A + E + Q EE EF K +E I+ L +I
Sbjct: 1667 DAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKA 1726
Query: 95 --TLESEESQISAKEQIILEKLKETEKSFKDFQKGFSS------------TDGAVYAMEI 140
LE + S++ ++ I +L+E ++ + K + D E
Sbjct: 1727 KTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEA 1786
Query: 141 NVEKDK-------QTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGV 193
N EK + + + L S + V ++ K+ + T++ +E R+ +E+
Sbjct: 1787 NKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE-RTQVKRLESLA 1845
Query: 194 HKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDH 253
+L +++E+L ++ Q E+ L KE M E + SRK H
Sbjct: 1846 SRLK-ENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEM--GELARKEAEASRKKH 1902
Score = 30.8 bits (68), Expect = 2.1
Identities = 55/329 (16%), Positives = 131/329 (39%), Gaps = 34/329 (10%)
Query: 11 ERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRR 70
ERL+A E ++ QT+ + ++Q+ +++ ++ +++++R + G ++++A
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQM--EVMEMEVMEARLIRAAEI-----NGEVDDDDAGGE 1370
Query: 71 QSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSS 130
+ E V++++ +RL+QE + K ++ + ++ E+ D Q
Sbjct: 1371 WRLKYERAVREVDFTKKRLQQEFED----------KLEVEQQNKRQLERRLGDLQADSEE 1420
Query: 131 TDGAVYAMEINVEK-DKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVV 189
+ A+ ++ ++ + +TK+ +K + +D +E +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
Query: 190 ENGVHK---LSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMV 246
+ + + + L Q+ + + +++ V + L EA L V
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 247 HKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNI----------EDEEETKK 296
K +D + Q+ + AG L+Q + M + + DEE +
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
Query: 297 VLGYDETIKAELVLID---EDDEKSLREK 322
+ +K V ++ ED +K LREK
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREK 1629
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/200 (23%), Positives = 86/200 (43%), Gaps = 25/200 (12%)
Query: 2 EMAEAELHKERLQAIA-EKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAG 60
E+ + +LH E Q E K+Q + + Q E+ + + K+ REK +L
Sbjct: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA---- 1493
Query: 61 TAEEEEARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKS 120
E + ++Q EE + + + LE E+Q + S+ES+ A + ++L++ E
Sbjct: 1494 ---EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
Query: 121 FKDFQKGFSSTDGAV-------YAMEINVEKDKQTGETKILSTSTIGPEGVH--QKGVK- 170
KD ++ G + +E+ +E+ +QT ++ S E QK +K
Sbjct: 1551 VKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ 1610
Query: 171 -------VYDDGTKVVYEVR 183
Y+D KV+ E R
Sbjct: 1611 MEVQLEEEYEDKQKVLREKR 1630
Score = 33.5 bits (75), Expect = 0.32
Identities = 38/137 (27%), Positives = 59/137 (43%), Gaps = 23/137 (16%)
Query: 5 EAELHKERLQAIAEKRKRQTEIEGKRQ-------QLDEQILLLQHSKSKVLREKWLLQGI 57
E E+ + R E R E+E RQ Q++ Q+ K KVLREK L+G
Sbjct: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
Query: 58 PAGTAEEEEARRRQSE----EDEFRVKQLEDNIQRL----------EQEIQTLES--EES 101
A +++ R +SE +D R K L + Q + ++EI L++ EES
Sbjct: 1636 LATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEES 1695
Query: 102 QISAKEQIILEKLKETE 118
+ + + K E E
Sbjct: 1696 EFTCAAAVKARKAMEVE 1712
Score = 32.0 bits (71), Expect = 0.94
Identities = 64/300 (21%), Positives = 114/300 (38%), Gaps = 55/300 (18%)
Query: 1 MEMAEAELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLRE-----KWLLQ 55
ME+ E ++++ + + EKR E+EGK L +Q+ K LR+ K LL
Sbjct: 1611 MEVQLEEEYEDKQKVLREKR----ELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLA 1666
Query: 56 GIP---------AGTAEEEEARRRQSEEDEFRV-------KQLEDNIQRLEQEIQ----- 94
A + E + Q EE EF K +E I+ L +I
Sbjct: 1667 DAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKA 1726
Query: 95 --TLESEESQISAKEQIILEKLKETEKSFKDFQKGFSS------------TDGAVYAMEI 140
LE + S++ ++ I +L+E ++ + K + D E
Sbjct: 1727 KTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEA 1786
Query: 141 NVEKDK-------QTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVVENGV 193
N EK + + + L S + V ++ K+ + T++ +E R+ +E+
Sbjct: 1787 NKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE-RTQVKRLESLA 1845
Query: 194 HKLSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMVHKSRKDH 253
+L +++E+L ++ Q E+ L KE M E + SRK H
Sbjct: 1846 SRLK-ENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEM--GELARKEAEASRKKH 1902
Score = 30.8 bits (68), Expect = 2.1
Identities = 55/329 (16%), Positives = 131/329 (39%), Gaps = 34/329 (10%)
Query: 11 ERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEEEARRR 70
ERL+A E ++ QT+ + ++Q+ +++ ++ +++++R + G ++++A
Sbjct: 1318 ERLRAEKEMKELQTQYDALKKQM--EVMEMEVMEARLIRAAEI-----NGEVDDDDAGGE 1370
Query: 71 QSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEKLKETEKSFKDFQKGFSS 130
+ E V++++ +RL+QE + K ++ + ++ E+ D Q
Sbjct: 1371 WRLKYERAVREVDFTKKRLQQEFED----------KLEVEQQNKRQLERRLGDLQADSEE 1420
Query: 131 TDGAVYAMEINVEK-DKQTGETKILSTSTIGPEGVHQKGVKVYDDGTKVVYEVRSGGTVV 189
+ A+ ++ ++ + +TK+ +K + +D +E +
Sbjct: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
Query: 190 ENGVHK---LSTKDVEELIQKAGQSSLGGGHVSERTVIADGSLSHPKEHMLCKEAKLEMV 246
+ + + + L Q+ + + +++ V + L EA L V
Sbjct: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
Query: 247 HKSRKDHSSGNPGQQAQAPSAAGPEANLDQPVTMIFMGYQNI----------EDEEETKK 296
K +D + Q+ + AG L+Q + M + + DEE +
Sbjct: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
Query: 297 VLGYDETIKAELVLID---EDDEKSLREK 322
+ +K V ++ ED +K LREK
Sbjct: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREK 1629
>gi|110611218 ribosome binding protein 1 [Homo sapiens]
Length = 977
Score = 44.7 bits (104), Expect = 1e-04
Identities = 29/108 (26%), Positives = 51/108 (47%)
Query: 6 AELHKERLQAIAEKRKRQTEIEGKRQQLDEQILLLQHSKSKVLREKWLLQGIPAGTAEEE 65
AELH + + AE R + E+ G QL E ++ + LL+ A A++
Sbjct: 483 AELHSKLQSSEAEVRSKCEELSGLHGQLQEARAENSQLTERIRSIEALLEAGQARDAQDV 542
Query: 66 EARRRQSEEDEFRVKQLEDNIQRLEQEIQTLESEESQISAKEQIILEK 113
+A + ++++ + R+K+LE + LE+E L Q K + EK
Sbjct: 543 QASQAEADQQQTRLKELESQVSGLEKEAIELREAVEQQKVKNNDLREK 590
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.334
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,611,086
Number of Sequences: 37866
Number of extensions: 696092
Number of successful extensions: 7007
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 240
Number of HSP's successfully gapped in prelim test: 551
Number of HSP's that attempted gapping in prelim test: 4048
Number of HSP's gapped (non-prelim): 2558
length of query: 379
length of database: 18,247,518
effective HSP length: 104
effective length of query: 275
effective length of database: 14,309,454
effective search space: 3935099850
effective search space used: 3935099850
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.