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Search of human proteins with 78191798
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
(638 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 1345 0.0
gi|4503627 coagulation factor XI precursor [Homo sapiens] 793 0.0
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 218 1e-56
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 217 2e-56
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 217 3e-56
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 217 3e-56
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 209 8e-54
gi|223942069 enterokinase precursor [Homo sapiens] 207 2e-53
gi|4506153 prostasin preproprotein [Homo sapiens] 207 2e-53
gi|13994276 marapsin [Homo sapiens] 204 3e-52
gi|33695155 hepsin [Homo sapiens] 202 6e-52
gi|4504481 hepsin [Homo sapiens] 202 6e-52
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 202 8e-52
gi|117956391 protease, serine, 33 [Homo sapiens] 194 2e-49
gi|21614531 testisin isoform 2 [Homo sapiens] 194 3e-49
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 194 3e-49
gi|5803197 testisin isoform 1 [Homo sapiens] 193 5e-49
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 192 6e-49
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 188 1e-47
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap... 188 1e-47
gi|194018492 transmembrane protease, serine 11F [Homo sapiens] 188 1e-47
gi|29244926 corin [Homo sapiens] 187 2e-47
gi|4758508 transmembrane protease, serine 11D [Homo sapiens] 187 3e-47
gi|110578663 hypothetical protein LOC203074 [Homo sapiens] 186 7e-47
gi|58218970 protease, serine, 36 [Homo sapiens] 185 1e-46
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 182 6e-46
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 182 6e-46
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 182 6e-46
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 182 6e-46
gi|11545839 protease, serine, 22 [Homo sapiens] 182 8e-46
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 1345 bits (3482), Expect = 0.0
Identities = 638/638 (100%), Positives = 638/638 (100%)
Query: 1 MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLF 60
MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLF
Sbjct: 1 MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLF 60
Query: 61 SFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVD 120
SFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVD
Sbjct: 61 SFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVD 120
Query: 121 MRGVNFNVSKVSSVEECQKRCTSNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIK 180
MRGVNFNVSKVSSVEECQKRCTSNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIK
Sbjct: 121 MRGVNFNVSKVSSVEECQKRCTSNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIK 180
Query: 181 VLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFF 240
VLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFF
Sbjct: 181 VLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFF 240
Query: 241 TFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGV 300
TFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGV
Sbjct: 241 TFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGV 300
Query: 301 DFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRI 360
DFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRI
Sbjct: 301 DFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRI 360
Query: 361 AYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCG 420
AYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCG
Sbjct: 361 AYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCG 420
Query: 421 GSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG 480
GSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG
Sbjct: 421 GSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG 480
Query: 481 NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNI 540
NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNI
Sbjct: 481 NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNI 540
Query: 541 PLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE 600
PLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE
Sbjct: 541 PLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE 600
Query: 601 GCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA 638
GCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
Sbjct: 601 GCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA 638
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 793 bits (2047), Expect = 0.0
Identities = 367/627 (58%), Positives = 465/627 (74%), Gaps = 3/627 (0%)
Query: 1 MILFKQATYFISLFATVSCGCLTQLYENAFFRGGDVASMYTPNAQYCQMRCTFHPRCLLF 60
MI Q +FI LF +VS C+TQL ++ F GGD+ +++TP+A+YCQ+ CT+HPRCLLF
Sbjct: 1 MIFLYQVVHFI-LFTSVSGECVTQLLKDTCFEGGDITTVFTPSAKYCQVVCTYHPRCLLF 59
Query: 61 SFLPASSINDMEKRFGCFLKDSVTGTLPKVHRTGAVSGHSLKQCGHQISACHRDIYKGVD 120
+F S D + F C LKDSVT TLP+V+RT A+SG+S KQC HQISAC++DIY +D
Sbjct: 60 TFTAESPSEDPTRWFTCVLKDSVTETLPRVNRTAAISGYSFKQCSHQISACNKDIYVDLD 119
Query: 121 MRGVNFNVSKVSSVEECQKRCTSNIRCQFFSYATQTFHKAEYRNNCLLKYSPGGTPTAIK 180
M+G+N+N S S +ECQ+RCT ++ C FF+YAT+ F E+RN CLLK++ GTPT I
Sbjct: 120 MKGINYNSSVAKSAQECQERCTDDVHCHFFTYATRQFPSLEHRNICLLKHTQTGTPTRIT 179
Query: 181 VLSNVESGFSLKPCALSEIGCHMNIFQHLAFSDVDVARVLTPDAFVCRTICTYHPNCLFF 240
L V SGFSLK CALS + C +IF + F+D ++ V+ PDAFVC ICT+HP CLFF
Sbjct: 180 KLDKVVSGFSLKSCALSNLACIRDIFPNTVFADSNIDSVMAPDAFVCGRICTHHPGCLFF 239
Query: 241 TFYTNVWKIESQRNVCLLKTSESGTPSSSTPQENTISGYSLLTCKRTLPEPCHSKIYPGV 300
TF++ W ESQRN+CLLKTSESG PS+ + +SG+SL +C+ ++P CHS Y
Sbjct: 240 TFFSQEWPKESQRNLCLLKTSESGLPSTRIKKSKALSGFSLQSCRHSIPVFCHSSFYHDT 299
Query: 301 DFGGEELNVTFVKGVNVCQETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRI 360
DF GEEL++ K CQ+ CT +RCQFFTY+ C E K KC+L+LS +GSPT+I
Sbjct: 300 DFLGEELDIVAAKSHEACQKLCTNAVRCQFFTYTPAQASCNEGKGKCYLKLSSNGSPTKI 359
Query: 361 AYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCG 420
+G G SGY+LRLC DN CTTK RIVGGT S GEWPWQV+L QRHLCG
Sbjct: 360 LHGRGGISGYTLRLCKM-DNE-CTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCG 417
Query: 421 GSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEG 480
GS+IG+QW+LTAAHCF G+ + R+YSGILN S+I +DT F ++EIIIH YK++E
Sbjct: 418 GSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAES 477
Query: 481 NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNI 540
+DIAL+KL+ +NYT+ Q+PICLPSKGD + IYT+CWVTGWG+ K + +IQN LQK I
Sbjct: 478 GYDIALLKLETTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKI 537
Query: 541 PLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE 600
PLVTNEECQKRY+ +KIT +M+CAGY+EGGKDACKGDSGGPL CKHN +W LVGITSWGE
Sbjct: 538 PLVTNEECQKRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE 597
Query: 601 GCARREQPGVYTKVAEYMDWILEKTQS 627
GCA+RE+PGVYT V EY+DWILEKTQ+
Sbjct: 598 GCAQRERPGVYTNVVEYVDWILEKTQA 624
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 218 bits (556), Expect = 1e-56
Identities = 115/306 (37%), Positives = 172/306 (56%), Gaps = 24/306 (7%)
Query: 319 QETCTKMIRCQFFTYSLLPEDCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTG 378
+E C + + C FT+ C++ C DG P G C+ G
Sbjct: 522 EEQCQEGVPCGTFTFQ-----CEDRSCVKKPNPQCDGRP-------DCRDGSDEEHCDCG 569
Query: 379 DNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-- 436
S+RIVGG SS GEWPWQ SLQV+ RH+CGG+LI +WV+TAAHCF
Sbjct: 570 LQG-----PSSRIVGGAVSSEGEWPWQASLQVR---GRHICGGALIADRWVITAAHCFQE 621
Query: 437 DGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYT 496
D + +W ++ G + + ++ +++H ++ ++D+AL++L P+ +
Sbjct: 622 DSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRS 681
Query: 497 EFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK 556
+P+CLP++ +CW+TGWG +E G I N LQKV++ L+ + C + Y+ Y+
Sbjct: 682 AAVRPVCLPARSHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYR-YQ 740
Query: 557 ITQRMVCAGYKEGGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVA 615
+T RM+CAGY++G KDAC+GDSGGPLVCK +G W L G+ SWG GC R GVYT++
Sbjct: 741 VTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLVSWGLGCGRPNYFGVYTRIT 800
Query: 616 EYMDWI 621
+ WI
Sbjct: 801 GVISWI 806
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 217 bits (553), Expect = 2e-56
Identities = 113/253 (44%), Positives = 157/253 (62%), Gaps = 13/253 (5%)
Query: 381 SVCTTKTST-RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF--D 437
S C + T RIVGG +S +WPWQVSL T H+CGG+LI QWVLTAAHCF
Sbjct: 315 SHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTT---HICGGTLIDAQWVLTAAHCFFVT 371
Query: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497
+ + W++Y+G NL + + + I EIII+ NY E ++DIAL++L PL +
Sbjct: 372 REKVLEGWKVYAGTSNLHQLPEA---ASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSA 428
Query: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN-ILQKVNIPLVTNEECQKR--YQD 554
P CLP G T ++ CW+TG+G ++E + + L++V + L+ ++C Y
Sbjct: 429 HIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDS 488
Query: 555 YKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKV 614
Y +T RM+CAG GG+D+C+GDSGGPLVC+ N W L G+TSWG GC +R +PGVYTKV
Sbjct: 489 Y-LTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKV 547
Query: 615 AEYMDWILEKTQS 627
E + WI K +S
Sbjct: 548 TEVLPWIYSKMES 560
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 217 bits (552), Expect = 3e-56
Identities = 109/260 (41%), Positives = 157/260 (60%), Gaps = 10/260 (3%)
Query: 371 SLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVL 430
SLR G N + +RIVGG ++ G WPWQVSL V+ H+CGGS+I +W++
Sbjct: 275 SLRCIACGVN--LNSSRQSRIVGGESALPGAWPWQVSLHVQNV---HVCGGSIITPEWIV 329
Query: 431 TAAHCFDGLPLQDVWR--IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIK 488
TAAHC + PL + W ++GIL S + + Q++++I H NY N+DIAL+K
Sbjct: 330 TAAHCVEK-PLNNPWHWTAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMK 387
Query: 489 LQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC 548
LQ PL + + KP+CLP+ G CW++GWG ++EKG+ +L + L+ + C
Sbjct: 388 LQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRC 447
Query: 549 QKRY-QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQ 607
RY D IT M+CAG+ +G D+C+GDSGGPLV N +W L+G TSWG GCA+ +
Sbjct: 448 NSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYR 507
Query: 608 PGVYTKVAEYMDWILEKTQS 627
PGVY V + DWI + ++
Sbjct: 508 PGVYGNVMVFTDWIYRQMRA 527
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 217 bits (552), Expect = 3e-56
Identities = 109/260 (41%), Positives = 157/260 (60%), Gaps = 10/260 (3%)
Query: 371 SLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVL 430
SLR G N + +RIVGG ++ G WPWQVSL V+ H+CGGS+I +W++
Sbjct: 238 SLRCIACGVN--LNSSRQSRIVGGESALPGAWPWQVSLHVQNV---HVCGGSIITPEWIV 292
Query: 431 TAAHCFDGLPLQDVWR--IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIK 488
TAAHC + PL + W ++GIL S + + Q++++I H NY N+DIAL+K
Sbjct: 293 TAAHCVEK-PLNNPWHWTAFAGILRQSFMFYGAGY-QVEKVISHPNYDSKTKNNDIALMK 350
Query: 489 LQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC 548
LQ PL + + KP+CLP+ G CW++GWG ++EKG+ +L + L+ + C
Sbjct: 351 LQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRC 410
Query: 549 QKRY-QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQ 607
RY D IT M+CAG+ +G D+C+GDSGGPLV N +W L+G TSWG GCA+ +
Sbjct: 411 NSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYR 470
Query: 608 PGVYTKVAEYMDWILEKTQS 627
PGVY V + DWI + ++
Sbjct: 471 PGVYGNVMVFTDWIYRQMRA 490
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 209 bits (531), Expect = 8e-54
Identities = 103/241 (42%), Positives = 147/241 (60%), Gaps = 7/241 (2%)
Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447
S+RIVGG S +WPWQ SLQ + HLCGGS+I W++TAAHC L L W I
Sbjct: 214 SSRIVGGNMSLLSQWPWQASLQFQ---GYHLCGGSVITPLWIITAAHCVYDLYLPKSWTI 270
Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507
G+++L D P +++I+ H YK +DIAL+KL PL + E +P+CLP+
Sbjct: 271 QVGLVSLLD--NPAPSHLVEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNS 328
Query: 508 GDTSTIYTNCWVTGWGFSKE-KGEIQNILQKVNIPLVTNEECQKR-YQDYKITQRMVCAG 565
+ CW +GWG +++ G+ +L +PL++N+ C R I+ M+CAG
Sbjct: 329 EENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCAG 388
Query: 566 YKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKT 625
Y GG D+C+GDSGGPLVC+ +W+LVG TS+G GCA +PGVYT+V ++DWI E+
Sbjct: 389 YLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIHEQM 448
Query: 626 Q 626
+
Sbjct: 449 E 449
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 207 bits (528), Expect = 2e-53
Identities = 98/234 (41%), Positives = 147/234 (62%), Gaps = 5/234 (2%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ-DVWRIY 448
+IVGG+N+ G WPW V L R LCG SL+ W+++AAHC G L+ W
Sbjct: 784 KIVGGSNAKEGAWPWVVGLYY---GGRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAI 840
Query: 449 SGILNLSDITKDTPFSQ-IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507
G+ S++T + I EI+I+ +Y ++DIA++ L+ +NYT++ +PICLP +
Sbjct: 841 LGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEE 900
Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567
NC + GWG +G NILQ+ ++PL++NE CQ++ +Y IT+ M+CAGY+
Sbjct: 901 NQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENMICAGYE 960
Query: 568 EGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621
EGG D+C+GDSGGPL+C+ N W L G+TS+G CA +PGVY +V+ + +WI
Sbjct: 961 EGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI 1014
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 207 bits (528), Expect = 2e-53
Identities = 101/256 (39%), Positives = 145/256 (56%), Gaps = 12/256 (4%)
Query: 378 GDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD 437
G + C RI GG+++ G+WPWQVS+ + H+CGGSL+ QWVL+AAHCF
Sbjct: 32 GAEAPCGVAPQARITGGSSAVAGQWPWQVSITYEGV---HVCGGSLVSEQWVLSAAHCFP 88
Query: 438 GLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTE 497
++ + + G L ++D S +K+II H +Y DIAL++L P+ ++
Sbjct: 89 SEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQLSRPITFSR 148
Query: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEI--QNILQKVNIPLVTNEECQKRY--- 552
+ +PICLP+ + +C VTGWG + LQ++ +PL++ E C Y
Sbjct: 149 YIRPICLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNID 208
Query: 553 ----QDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQP 608
+ + + + MVCAGY EGGKDAC+GDSGGPL C G+W L GI SWG+ C R +P
Sbjct: 209 AKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRP 268
Query: 609 GVYTKVAEYMDWILEK 624
GVYT + Y WI K
Sbjct: 269 GVYTLASSYASWIQSK 284
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 204 bits (518), Expect = 3e-52
Identities = 99/242 (40%), Positives = 144/242 (59%), Gaps = 13/242 (5%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449
R+VGG ++ GEWPWQVS+Q + H CGGSLI QWVLTAAHCF ++++
Sbjct: 34 RMVGGQDTQEGEWPWQVSIQRNGS---HFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLL 90
Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509
G L +++++++ + Y+ + + D+AL++L+AP+ +T + P+CLP
Sbjct: 91 GARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSV 150
Query: 510 TSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTNEEC--------QKRYQDYKITQ 559
NCWVTGWG E+ + ILQK+ +P++ +C + YQ I
Sbjct: 151 IFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKN 210
Query: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619
M+CAG++EG KDACKGDSGGPLVC W G+ SWGEGCAR+ +PGVY +V + +
Sbjct: 211 DMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHN 270
Query: 620 WI 621
WI
Sbjct: 271 WI 272
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 202 bits (515), Expect = 6e-52
Identities = 106/255 (41%), Positives = 152/255 (59%), Gaps = 25/255 (9%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQDVWRIY 448
RIVGG ++S G WPWQVSL+ HLCGGSL+ WVLTAAHCF + + WR++
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 218
Query: 449 SGILNLSDITKDTPFSQ---IKEIIIHQNY------KVSEGNHDIALIKLQAPLNYTEFQ 499
+G + + +P ++ ++ H Y E ++DIAL+ L +PL TE+
Sbjct: 219 AGA-----VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYI 273
Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ-KRYQDYKIT 558
+P+CLP+ G C VTGWG ++ G+ +LQ+ +P+++N+ C + +I
Sbjct: 274 QPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIK 333
Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCK----HNGMWRLVGITSWGEGCARREQPGVYTKV 614
+M CAGY EGG DAC+GDSGGP VC+ WRL GI SWG GCA ++PGVYTKV
Sbjct: 334 PKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKV 393
Query: 615 AEYMDWILE--KTQS 627
+++ +WI + KT S
Sbjct: 394 SDFREWIFQAIKTHS 408
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 202 bits (515), Expect = 6e-52
Identities = 106/255 (41%), Positives = 152/255 (59%), Gaps = 25/255 (9%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQDVWRIY 448
RIVGG ++S G WPWQVSL+ HLCGGSL+ WVLTAAHCF + + WR++
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYD---GAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVF 218
Query: 449 SGILNLSDITKDTPFSQ---IKEIIIHQNY------KVSEGNHDIALIKLQAPLNYTEFQ 499
+G + + +P ++ ++ H Y E ++DIAL+ L +PL TE+
Sbjct: 219 AGA-----VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYI 273
Query: 500 KPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQ-KRYQDYKIT 558
+P+CLP+ G C VTGWG ++ G+ +LQ+ +P+++N+ C + +I
Sbjct: 274 QPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIK 333
Query: 559 QRMVCAGYKEGGKDACKGDSGGPLVCK----HNGMWRLVGITSWGEGCARREQPGVYTKV 614
+M CAGY EGG DAC+GDSGGP VC+ WRL GI SWG GCA ++PGVYTKV
Sbjct: 334 PKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKV 393
Query: 615 AEYMDWILE--KTQS 627
+++ +WI + KT S
Sbjct: 394 SDFREWIFQAIKTHS 408
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 202 bits (514), Expect = 8e-52
Identities = 99/245 (40%), Positives = 147/245 (60%), Gaps = 8/245 (3%)
Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDV--W 445
++RIVGG + + G WPWQ S+ + RH CGGS++ +WV+TAAHC L + W
Sbjct: 215 ASRIVGGQSVAPGRWPWQASVALGF---RHTCGGSVLAPRWVVTAAHCMHSFRLARLSSW 271
Query: 446 RIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP 505
R+++G+++ S + + + ++ II H Y ++D+AL++LQ LN+++ +CLP
Sbjct: 272 RVHAGLVSHSAV-RPHQGALVERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLP 330
Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQN-ILQKVNIPLVTNEECQKR-YQDYKITQRMVC 563
+K + CWV+GWG + + +LQ +PL + + C +T RM+C
Sbjct: 331 AKEQHFPKGSRCWVSGWGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLC 390
Query: 564 AGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623
AGY +G DAC+GDSGGPLVC WRLVG+ SWG GCA PGVY KVAE++DWI +
Sbjct: 391 AGYLDGRADACQGDSGGPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHD 450
Query: 624 KTQSS 628
Q S
Sbjct: 451 TAQDS 455
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 194 bits (493), Expect = 2e-49
Identities = 107/272 (39%), Positives = 145/272 (53%), Gaps = 20/272 (7%)
Query: 360 IAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLC 419
+ G G+ G C + S+RIVGG + GEWPWQ S+Q + H+C
Sbjct: 13 LVLGAAGTQGRKSAACGQ-------PRMSSRIVGGRDGRDGEWPWQASIQHR---GAHVC 62
Query: 420 GGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSE 479
GGSLI QWVLTAAHCF L +R+ G L L + T ++ +++ +Y
Sbjct: 63 GGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDG 122
Query: 480 GNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNI--LQK 537
D+AL++L+ P+ + +P+CLP G T C VTGWG + + LQ
Sbjct: 123 ARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQG 182
Query: 538 VNIPLVTNEECQKRYQ---DYKITQRMV-----CAGYKEGGKDACKGDSGGPLVCKHNGM 589
V +PL+ + C Y D +R+V CAGY +G KDAC+GDSGGPL C +G
Sbjct: 183 VRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGS 242
Query: 590 WRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621
W LVG+ SWG+GCA +PGVYT VA Y WI
Sbjct: 243 WVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 194 bits (492), Expect = 3e-49
Identities = 102/257 (39%), Positives = 148/257 (57%), Gaps = 16/257 (6%)
Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFD-GLPLQDVWR 446
++RIVGG ++ G WPWQ SL++ H+CG SL+ H+W LTAAHCF+ L W
Sbjct: 39 TSRIVGGEDAELGRWPWQGSLRLW---DSHVCGVSLLSHRWALTAAHCFETDLSDPSGWM 95
Query: 447 IYSGILNL--SDITKDTPFSQ--IKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPI 502
+ G L S + +++ + I + Y + +DIAL+KL AP+ YT+ +PI
Sbjct: 96 VQFGQLTSMPSFWSLQAYYTRYFVSNIYLSPRY-LGNSPYDIALVKLSAPVTYTKHIQPI 154
Query: 503 CLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTNEECQKRYQDYKITQR 560
CL + T+CWVTGWG+ KE + + LQ+V + ++ N C + Y +
Sbjct: 155 CLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYSFRKD 214
Query: 561 ----MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAE 616
MVCAG +GGKDAC GDSGGPL C NG+W +G+ SWG GC R +PGVYT ++
Sbjct: 215 IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISH 274
Query: 617 YMDWILEKTQSSDGKAQ 633
+ +WI +K + G +Q
Sbjct: 275 HFEWI-QKLMAQSGMSQ 290
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 194 bits (492), Expect = 3e-49
Identities = 107/268 (39%), Positives = 148/268 (55%), Gaps = 15/268 (5%)
Query: 369 GYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQW 428
G SLR G + RIVGG + G WPWQ SL+++ H+CGGSL+ QW
Sbjct: 16 GVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRV---HVCGGSLLSPQW 72
Query: 429 VLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNH-DIALI 487
VLTAAHCF G ++++ G L +IT FS +++II+H + G DIAL+
Sbjct: 73 VLTAAHCFSGSLNSSDYQVHLGEL---EITLSPHFSTVRQIILHSSPSGQPGTSGDIALV 129
Query: 488 KLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTN 545
+L P+ + P+CLP D CWVTGWG+++E + L++V + +V
Sbjct: 130 ELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDT 189
Query: 546 EECQKRYQDYK---ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGC 602
E C++ Y + M+CA G DAC+ DSGGPLVC+ NG W GI SWGEGC
Sbjct: 190 ETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDSGGPLVCQVNGAWVQAGIVSWGEGC 246
Query: 603 ARREQPGVYTKVAEYMDWILEKTQSSDG 630
R +PGVYT+V Y++WI +S G
Sbjct: 247 GRPNRPGVYTRVPAYVNWIRRHITASGG 274
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 193 bits (490), Expect = 5e-49
Identities = 103/262 (39%), Positives = 148/262 (56%), Gaps = 24/262 (9%)
Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447
++RIVGG ++ G WPWQ SL++ H+CG SL+ H+W LTAAHCF+ D+
Sbjct: 39 TSRIVGGEDAELGRWPWQGSLRLW---DSHVCGVSLLSHRWALTAAHCFE--TYSDLSDP 93
Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSE--------GN--HDIALIKLQAPLNYTE 497
++ +T F ++ + Y VS GN +DIAL+KL AP+ YT+
Sbjct: 94 SGWMVQFGQLTSMPSFWSLQAY--YTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTK 151
Query: 498 FQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTNEECQKRYQDY 555
+PICL + T+CWVTGWG+ KE + + LQ+V + ++ N C + Y
Sbjct: 152 HIQPICLQASTFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY 211
Query: 556 KITQR----MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVY 611
+ MVCAG +GGKDAC GDSGGPL C NG+W +G+ SWG GC R +PGVY
Sbjct: 212 SFRKDIFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVY 271
Query: 612 TKVAEYMDWILEKTQSSDGKAQ 633
T ++ + +WI +K + G +Q
Sbjct: 272 TNISHHFEWI-QKLMAQSGMSQ 292
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 192 bits (489), Expect = 6e-49
Identities = 96/239 (40%), Positives = 139/239 (58%), Gaps = 6/239 (2%)
Query: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448
TRIVGG+ + GEWPWQVSL ++ + H CG L+ +W+L+AAHCFD W +
Sbjct: 825 TRIVGGSAAGRGEWPWQVSLWLR--RREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAF 882
Query: 449 SGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508
G LS + ++ I H Y + ++D+AL++L P+ + +PICLP
Sbjct: 883 LGTPFLSGA--EGQLERVARIYKHPFYNLYTLDYDVALLELAGPVRRSRLVRPICLPEPA 940
Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568
T C +TGWG +E G + LQK + L++ + C +R+ +I+ RM+CAG+ +
Sbjct: 941 PRPPDGTRCVITGWGSVREGGSMARQLQKAAVRLLSEQTC-RRFYPVQISSRMLCAGFPQ 999
Query: 569 GGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQ 626
GG D+C GD+GGPL C+ +G W L G+TSWG GC R PGVYT+VA WI + Q
Sbjct: 1000 GGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIGQHIQ 1058
Score = 189 bits (479), Expect = 9e-48
Identities = 99/252 (39%), Positives = 145/252 (57%), Gaps = 7/252 (2%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449
RIVGG +S GE+PWQ SL+ + H CG ++I +W+++AAHCF+ W Y
Sbjct: 202 RIVGGMEASPGEFPWQASLREN---KEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYV 258
Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509
G LS T +Q+ +I+ H Y + D+A+++L +PL + +P+CLP+
Sbjct: 259 GATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLPFGRHIQPVCLPAATH 318
Query: 510 TSTIYTNCWVTGWGFSKEKGEIQ-NILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKE 568
C ++GWG+ KE ++ +LQK + L+ C Y + +T RMVCAGY +
Sbjct: 319 IFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCASLY-GHSLTDRMVCAGYLD 377
Query: 569 GGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE-KTQ 626
G D+C+GDSGGPLVC+ +G + L GI SWG GCA +PGVY +V DWILE T+
Sbjct: 378 GKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEATTK 437
Query: 627 SSDGKAQMQSPA 638
+S A +PA
Sbjct: 438 ASMPLAPTMAPA 449
Score = 181 bits (459), Expect = 2e-45
Identities = 87/237 (36%), Positives = 146/237 (61%), Gaps = 7/237 (2%)
Query: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 448
TR+VGG ++ GE PWQVSL+ RH CG +++G +W+L+AAHCF+ ++ V R +
Sbjct: 502 TRVVGGFGAASGEVPWQVSLK---EGSRHFCGATVVGDRWLLSAAHCFNHTKVEQV-RAH 557
Query: 449 SGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKG 508
G +L + ++ +++H Y + D+A+++L +PL + ++ +P+CLP
Sbjct: 558 LGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPLAFNKYIQPVCLPLAI 617
Query: 509 DTSTIYTNCWVTGWGFSKEKGEIQ-NILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYK 567
+ C ++GWG ++E + +LQK ++ ++ + C Y ++ +T RM+CAG+
Sbjct: 618 QKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQKTCSVLY-NFSLTDRMICAGFL 676
Query: 568 EGGKDACKGDSGGPLVCKH-NGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623
EG D+C+GDSGGPL C+ G++ L GI SWG GCA+ ++PGVYT++ WILE
Sbjct: 677 EGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQVKKPGVYTRITRLKGWILE 733
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 188 bits (478), Expect = 1e-47
Identities = 98/235 (41%), Positives = 145/235 (61%), Gaps = 12/235 (5%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449
R+VGG +S WPWQVS+Q ++H+CGGS++ WVLTAAHCF W++ +
Sbjct: 199 RVVGGEEASVDSWPWQVSIQYD---KQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRA 255
Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509
G SD P + +III + + ++DIAL+KLQ PL ++ +PICLP +
Sbjct: 256 G----SDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDE 311
Query: 510 TSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEEC--QKRYQDYKITQRMVCAGY 566
T T W+ GWGF+K+ G++ +IL + ++ ++ + C YQ ++T++M+CAG
Sbjct: 312 ELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQG-EVTEKMMCAGI 370
Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621
EGG D C+GDSGGPL+ + + W +VGI SWG GC PGVYTKV+ Y++WI
Sbjct: 371 PEGGVDTCQGDSGGPLMYQ-SDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 424
>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
sapiens]
Length = 437
Score = 188 bits (478), Expect = 1e-47
Identities = 98/235 (41%), Positives = 145/235 (61%), Gaps = 12/235 (5%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYS 449
R+VGG +S WPWQVS+Q ++H+CGGS++ WVLTAAHCF W++ +
Sbjct: 204 RVVGGEEASVDSWPWQVSIQYD---KQHVCGGSILDPHWVLTAAHCFRKHTDVFNWKVRA 260
Query: 450 GILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509
G SD P + +III + + ++DIAL+KLQ PL ++ +PICLP +
Sbjct: 261 G----SDKLGSFPSLAVAKIIIIEFNPMYPKDNDIALMKLQFPLTFSGTVRPICLPFFDE 316
Query: 510 TSTIYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEEC--QKRYQDYKITQRMVCAGY 566
T T W+ GWGF+K+ G++ +IL + ++ ++ + C YQ ++T++M+CAG
Sbjct: 317 ELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCNADDAYQG-EVTEKMMCAGI 375
Query: 567 KEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621
EGG D C+GDSGGPL+ + + W +VGI SWG GC PGVYTKV+ Y++WI
Sbjct: 376 PEGGVDTCQGDSGGPLMYQ-SDQWHVVGIVSWGYGCGGPSTPGVYTKVSAYLNWI 429
>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
Length = 438
Score = 188 bits (478), Expect = 1e-47
Identities = 103/252 (40%), Positives = 144/252 (57%), Gaps = 9/252 (3%)
Query: 377 TGDNSVCTTKTST-RIVGGTNSSW-GEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAH 434
T N +ST RIV G ++ GEWPWQ SLQ L H CG SLI + W+LTAAH
Sbjct: 191 TSSNMPLPASSSTQRIVQGRETAMEGEWPWQASLQ--LIGSGHQCGASLISNTWLLTAAH 248
Query: 435 CFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLN 494
CF W G + IT +++II+H+NY +DIAL++L +
Sbjct: 249 CFWKNKDPTQWIATFG----ATITPPAVKRNVRKIILHENYHRETNENDIALVQLSTGVE 304
Query: 495 YTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQ 553
++ + +CLP T+ +VTG+G + G IQN L++ + ++ + C +K
Sbjct: 305 FSNIVQRVCLPDSSIKLPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVY 364
Query: 554 DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTK 613
D IT M+CAG+ EG DACKGDSGGPLV ++ +W +VGI SWG+ CA ++PGVYT+
Sbjct: 365 DGLITPGMLCAGFMEGKIDACKGDSGGPLVYDNHDIWYIVGIVSWGQSCALPKKPGVYTR 424
Query: 614 VAEYMDWILEKT 625
V +Y DWI KT
Sbjct: 425 VTKYRDWIASKT 436
>gi|29244926 corin [Homo sapiens]
Length = 1042
Score = 187 bits (476), Expect = 2e-47
Identities = 95/238 (39%), Positives = 141/238 (59%), Gaps = 6/238 (2%)
Query: 386 KTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVW 445
+ + RI+GG S G WPWQ SLQ + + H+CG LI +WVLT AHCF+G VW
Sbjct: 797 RMNKRILGGRTSRPGRWPWQCSLQSEPSG--HICGCVLIAKKWVLTVAHCFEGRENAAVW 854
Query: 446 RIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLP 505
++ GI NL + +K II+H Y + ++DI++++L ++ T + +P+CLP
Sbjct: 855 KVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDISETGYVRPVCLP 914
Query: 506 SKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAG 565
+ T C++TGWG K + LQ+ + +++ E CQ + IT RM+CAG
Sbjct: 915 NPEQWLEPDTYCYITGWGHMGNKMPFK--LQEGEVRIISLEHCQSYFDMKTITTRMICAG 972
Query: 566 YKEGGKDACKGDSGGPLVC-KHNGMWRLVGITSWGEGC-ARREQPGVYTKVAEYMDWI 621
Y+ G D+C GDSGGPLVC K G W L G+TSWG C ++ PGVY+ V+ +++WI
Sbjct: 973 YESGTVDSCMGDSGGPLVCEKPGGRWTLFGLTSWGSVCFSKVLGPGVYSNVSYFVEWI 1030
>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
Length = 418
Score = 187 bits (475), Expect = 3e-47
Identities = 98/263 (37%), Positives = 151/263 (57%), Gaps = 11/263 (4%)
Query: 365 QGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLI 424
Q ++ + + C G + + T + RI+GGT + G WPWQVSL++ H CGGSLI
Sbjct: 163 QAAANWLINECGAGPDLI--TLSEQRILGGTEAEEGSWPWQVSLRLN---NAHHCGGSLI 217
Query: 425 GHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDI 484
+ W+LTAAHCF W SGI T +++ I+IH NYK + +DI
Sbjct: 218 NNMWILTAAHCFRSNSNPRDWIATSGI----STTFPKLRMRVRNILIHNNYKSATHENDI 273
Query: 485 ALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVT 544
AL++L+ + +T+ +CLP+ + +VTGWG + G L++ + +++
Sbjct: 274 ALVRLENSVTFTKDIHSVCLPAATQNIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIIS 333
Query: 545 NEECQKRYQ-DYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHN-GMWRLVGITSWGEGC 602
N+ C + + I M+CAG +GG DAC+GDSGGPLV + + +W +VGI SWG+ C
Sbjct: 334 NDVCNAPHSYNGAILSGMLCAGVPQGGVDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQC 393
Query: 603 ARREQPGVYTKVAEYMDWILEKT 625
++PGVYT+V Y+DWI ++T
Sbjct: 394 GLPDKPGVYTRVTAYLDWIRQQT 416
>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
Length = 352
Score = 186 bits (471), Expect = 7e-47
Identities = 103/257 (40%), Positives = 151/257 (58%), Gaps = 18/257 (7%)
Query: 378 GDNSVCTTKTS-TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF 436
GD S+ +T +RI GG + GE+PWQVS+Q + CGGS++ W+LTAAHC
Sbjct: 54 GDRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQAR---SEPFCGGSILNKWWILTAAHCL 110
Query: 437 DGLPLQDVWRIYSGILNLSDITKDTPFSQIKE---IIIHQNYKVSEGNHDIALIKLQAPL 493
L S +L +D+T +P +IKE II+H+++K + ++DIAL+ L +P+
Sbjct: 111 YSEELFP--EELSVVLGTNDLT--SPSMEIKEVASIILHKDFKRANMDNDIALLLLASPI 166
Query: 494 NYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSK--EKGEIQNILQKVNIPLVTNEECQKR 551
+ + PICLP++ +T + CWV GWG + +K ++ L K + ++ EEC K
Sbjct: 167 KLDDLKVPICLPTQPGPAT-WRECWVAGWGQTNAADKNSVKTDLMKAPMVIMDWEECSKM 225
Query: 552 YQDYKITQRMVCAGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCARREQPG 609
+ K+T+ M+CAGYK DACKGDSGGPLVC + W VGI SWG+ C + PG
Sbjct: 226 FP--KLTKNMLCAGYKNESYDACKGDSGGPLVCTPEPGEKWYQVGIISWGKSCGEKNTPG 283
Query: 610 VYTKVAEYMDWILEKTQ 626
+YT + Y WI + TQ
Sbjct: 284 IYTSLVNYNLWIEKVTQ 300
>gi|58218970 protease, serine, 36 [Homo sapiens]
Length = 855
Score = 185 bits (470), Expect = 1e-46
Identities = 102/254 (40%), Positives = 134/254 (52%), Gaps = 15/254 (5%)
Query: 388 STRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF---DGLPLQDV 444
S RIVGG+N+ G WPWQVSL H+CGGSLI WVL+AAHCF L
Sbjct: 44 SARIVGGSNAQPGTWPWQVSLH---HGGGHICGGSLIAPSWVLSAAHCFMTNGTLEPAAE 100
Query: 445 WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICL 504
W + G+ + + I++ NY E D+AL++L +P + P+CL
Sbjct: 101 WSVLLGVHSQDGPLDGAHTRAVAAIVVPANYSQVELGADLALLRLASPASLGPAVWPVCL 160
Query: 505 PSKGDTSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTNEECQKRYQD-------Y 555
P T CW TGWG +E + +LQ+V + L+ CQ Y
Sbjct: 161 PRASHRFVHGTACWATGWGDVQEADPLPLPWVLQEVELRLLGEATCQCLYSQPGPFNLTL 220
Query: 556 KITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVA 615
+I M+CAGY EG +D C+GDSGGPLVC+ G W GITS+G GC RR +PGV+T VA
Sbjct: 221 QILPGMLCAGYPEGRRDTCQGDSGGPLVCEEGGRWFQAGITSFGFGCGRRNRPGVFTAVA 280
Query: 616 EYMDWILEKTQSSD 629
Y WI E+ S+
Sbjct: 281 TYEAWIREQVMGSE 294
Score = 71.6 bits (174), Expect = 2e-12
Identities = 61/244 (25%), Positives = 100/244 (40%), Gaps = 33/244 (13%)
Query: 400 GEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF------DGLPLQ-DVWRIYSGIL 452
G WPW+ QV + R C G+L+ WVL A CF D P D WR+
Sbjct: 332 GAWPWEA--QVMVPGSRP-CHGALVSESWVLAPASCFLDPNSSDSPPRDLDAWRVL---- 384
Query: 453 NLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTST 512
+ ++ ++ H+N + D+AL++L+ P+N + +P+CLP
Sbjct: 385 ----LPSRPRAERVARLVQHENASWDNAS-DLALLQLRTPVNLSAASRPVCLPHPEHYFL 439
Query: 513 IYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRY--QDYKI-----TQRMVCAG 565
+ C + WG + +L+ L+ C Y Q + +C
Sbjct: 440 PGSRCRLARWGRGEPALGPGALLE---AELLGGWWCHCLYGRQGAAVPLPGDPPHALCPA 496
Query: 566 YKEGGK-DACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 624
Y+E + +C DS L+C+ G W L GI + GC R P + + + WI
Sbjct: 497 YQEKEEVGSCWNDSRWSLLCQEEGTWFLAGIRDFPSGCLR---PRAFFPLQTHGPWISHV 553
Query: 625 TQSS 628
T+ +
Sbjct: 554 TRGA 557
Score = 65.1 bits (157), Expect = 2e-10
Identities = 57/202 (28%), Positives = 85/202 (42%), Gaps = 18/202 (8%)
Query: 402 WPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF--DGLPLQDVWRIYSGILNLSDITK 459
WPW + V A +C G L+ WVL A HC G +Y G S + +
Sbjct: 601 WPWLAEVHV---AGDRVCTGILLAPGWVLAATHCVLRPGSTTVPYIEVYLGRAGASSLPQ 657
Query: 460 DTPFSQIKEIIIHQNYKVSEG-NHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIYTNCW 518
Q+ ++I G +AL++L + + + PICL G +CW
Sbjct: 658 G---HQVSRLVISIRLPQHLGLRPPLALLELSSRVEPSPSALPICLHPAGIPPG--ASCW 712
Query: 519 VTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYKITQRMVCAGYKEGGKDACKGDS 578
V GW KE + + V+I +T C YQ + +C Y EG ++ C+ S
Sbjct: 713 VLGW---KEPQDRVPVAAAVSI--LTQRICDCLYQGI-LPPGTLCVLYAEGQENRCEMTS 766
Query: 579 GGPLVCK-HNGMWRLVGITSWG 599
PL+C+ G W LVG+ G
Sbjct: 767 APPLLCQMTEGSWILVGMAVQG 788
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 182 bits (463), Expect = 6e-46
Identities = 101/243 (41%), Positives = 137/243 (56%), Gaps = 16/243 (6%)
Query: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC-FDGLPLQDVWRI 447
+R++GG + +WPWQVSLQ T+ H CGGSLI +WVLTAAHC F G + +
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQ---TSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWL 217
Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507
+GI D + +++II N+ + DIAL L +NY+ +P CLP K
Sbjct: 218 LAGIGRW-----DQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272
Query: 508 GDTSTIYTNCWVTGWGFSKEK--GEIQNILQKVNIPLVTNEEC-----QKRYQDYKITQR 560
T CWVTGWG E G + +LQ+ + ++ +E+C K K+ R
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTR 332
Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620
GY + GKDAC+GDSGGPLVC+ NG W VGI SWG GC R+ PGVYT+V+ Y W
Sbjct: 333 GTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKW 392
Query: 621 ILE 623
I++
Sbjct: 393 IID 395
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 182 bits (463), Expect = 6e-46
Identities = 101/243 (41%), Positives = 137/243 (56%), Gaps = 16/243 (6%)
Query: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC-FDGLPLQDVWRI 447
+R++GG + +WPWQVSLQ T+ H CGGSLI +WVLTAAHC F G + +
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQ---TSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWL 217
Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507
+GI D + +++II N+ + DIAL L +NY+ +P CLP K
Sbjct: 218 LAGIGRW-----DQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272
Query: 508 GDTSTIYTNCWVTGWGFSKEK--GEIQNILQKVNIPLVTNEEC-----QKRYQDYKITQR 560
T CWVTGWG E G + +LQ+ + ++ +E+C K K+ R
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTR 332
Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620
GY + GKDAC+GDSGGPLVC+ NG W VGI SWG GC R+ PGVYT+V+ Y W
Sbjct: 333 GTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKW 392
Query: 621 ILE 623
I++
Sbjct: 393 IID 395
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 182 bits (463), Expect = 6e-46
Identities = 101/243 (41%), Positives = 137/243 (56%), Gaps = 16/243 (6%)
Query: 389 TRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHC-FDGLPLQDVWRI 447
+R++GG + +WPWQVSLQ T+ H CGGSLI +WVLTAAHC F G + +
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQ---TSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWL 217
Query: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507
+GI D + +++II N+ + DIAL L +NY+ +P CLP K
Sbjct: 218 LAGIGRW-----DQAWKHLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272
Query: 508 GDTSTIYTNCWVTGWGFSKEK--GEIQNILQKVNIPLVTNEEC-----QKRYQDYKITQR 560
T CWVTGWG E G + +LQ+ + ++ +E+C K K+ R
Sbjct: 273 LFEVEAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVTR 332
Query: 561 MVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDW 620
GY + GKDAC+GDSGGPLVC+ NG W VGI SWG GC R+ PGVYT+V+ Y W
Sbjct: 333 GTVCGYNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKW 392
Query: 621 ILE 623
I++
Sbjct: 393 IID 395
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 182 bits (463), Expect = 6e-46
Identities = 97/242 (40%), Positives = 136/242 (56%), Gaps = 11/242 (4%)
Query: 387 TSTRIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR 446
T +IV G +S G WPWQ S+Q K RH CG SLI +W+L+AAHCF W
Sbjct: 181 TGNKIVNGKSSLEGAWPWQASMQWK---GRHYCGASLISSRWLLSAAHCFAKKNNSKDWT 237
Query: 447 IYSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPS 506
+ GI+ + K +++ II H+NY + DIAL++L +++TE+ + ICLP
Sbjct: 238 VNFGIV----VNKPYMTRKVQNIIFHENYSSPGLHDDIALVQLAEEVSFTEYIRKICLPE 293
Query: 507 KGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK--ITQRMVCA 564
+ N VTGWG G ILQ+ + ++ N+ C Y Y +T M+CA
Sbjct: 294 AKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYA-YSGFVTDTMLCA 352
Query: 565 GYKEGGKDACKGDSGGPLVCKHN-GMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILE 623
G+ G DAC+ DSGGPL + +W LVGI SWG+GC ++ +PGVYT+V Y +WI
Sbjct: 353 GFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWITS 412
Query: 624 KT 625
KT
Sbjct: 413 KT 414
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 182 bits (462), Expect = 8e-46
Identities = 100/254 (39%), Positives = 145/254 (57%), Gaps = 13/254 (5%)
Query: 390 RIVGGTNSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCF-DGLPLQDVWRIY 448
R+VGG +S+ EWPW VS+Q T H C GSL+ +WV+TAAHCF D L ++ +
Sbjct: 49 RVVGGEDSTDSEWPWIVSIQKNGT---HHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVL 105
Query: 449 SGILNLSDITKDTPFSQIKEIIIHQNYKVSEGN-HDIALIKLQAPLNYTEFQKPICLPSK 507
G L + + + + H Y EG DIAL++L+ + ++E PICLP
Sbjct: 106 LGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDA 165
Query: 508 GDTSTIYTNCWVTGWGFSKEKGEIQN--ILQKVNIPLVTNEECQKRYQ----DYKITQRM 561
T+CW++GWG ++ + + LQK+ +P++ +E C Y IT+ M
Sbjct: 166 SIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDM 225
Query: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621
+CAGY EG +DAC GDSGGPL+C+ +G W L GI SWGEGCA R +PGVY ++ + W+
Sbjct: 226 LCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWV 285
Query: 622 LEKTQSSD--GKAQ 633
+ Q G+AQ
Sbjct: 286 EKIVQGVQLRGRAQ 299
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,528,216
Number of Sequences: 37866
Number of extensions: 1236498
Number of successful extensions: 3072
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 2312
Number of HSP's gapped (non-prelim): 199
length of query: 638
length of database: 18,247,518
effective HSP length: 109
effective length of query: 529
effective length of database: 14,120,124
effective search space: 7469545596
effective search space used: 7469545596
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.