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Search of human proteins with 78000158
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|78000158 eukaryotic translation initiation factor 2B,
subunit 4 delta isoform 2 [Homo sapiens]
(523 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|78000158 eukaryotic translation initiation factor 2B, subunit... 1023 0.0
gi|78000156 eukaryotic translation initiation factor 2B, subunit... 1016 0.0
gi|187607323 eukaryotic translation initiation factor 2B, subuni... 1000 0.0
gi|4503503 eukaryotic translation initiation factor 2B, subunit ... 104 2e-22
gi|7657058 eukaryotic translation initiation factor 2B, subunit ... 87 4e-17
gi|72534748 translation initiation factor eIF-2B subunit alpha/b... 69 1e-11
gi|23943880 translation initiation factor eIF-2B subunit alpha/b... 65 2e-10
gi|217035154 RCSD domain containing 1 [Homo sapiens] 43 6e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 42 0.001
gi|157785645 SPEG complex locus [Homo sapiens] 41 0.003
gi|167614488 TBC1 domain family, member 10B [Homo sapiens] 40 0.005
gi|17933774 transcription elongation factor A (SII)-like 2 [Homo... 40 0.005
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 39 0.009
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens] 39 0.009
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 39 0.012
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 39 0.015
gi|125656165 THO complex 2 [Homo sapiens] 38 0.020
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 38 0.020
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 38 0.020
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 38 0.020
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 38 0.020
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 38 0.026
gi|58761546 amine oxidase (flavin containing) domain 2 isoform b... 38 0.026
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 38 0.026
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 38 0.026
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 38 0.026
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 38 0.026
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 38 0.026
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 38 0.026
gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo sa... 37 0.034
>gi|78000158 eukaryotic translation initiation factor 2B, subunit 4
delta isoform 2 [Homo sapiens]
Length = 523
Score = 1023 bits (2644), Expect = 0.0
Identities = 523/523 (100%), Positives = 523/523 (100%)
Query: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60
MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
Sbjct: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60
Query: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120
GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
Sbjct: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120
Query: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 180
EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
Sbjct: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 180
Query: 181 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 240
SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
Sbjct: 181 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 240
Query: 241 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 300
TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
Sbjct: 241 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 300
Query: 301 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 360
RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
Sbjct: 301 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 360
Query: 361 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 420
VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
Sbjct: 361 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 420
Query: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 480
AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
Sbjct: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 480
Query: 481 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523
SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
Sbjct: 481 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523
>gi|78000156 eukaryotic translation initiation factor 2B, subunit 4
delta isoform 3 [Homo sapiens]
Length = 522
Score = 1016 bits (2628), Expect = 0.0
Identities = 522/523 (99%), Positives = 522/523 (99%), Gaps = 1/523 (0%)
Query: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60
MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET
Sbjct: 1 MAAVAVAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPET 60
Query: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120
GSAVSAAQCQ GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG
Sbjct: 61 GSAVSAAQCQ-GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 119
Query: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 180
EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF
Sbjct: 120 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLF 179
Query: 181 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 240
SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY
Sbjct: 180 SHLPQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDY 239
Query: 241 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 300
TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL
Sbjct: 240 TTPPNEELSRDLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSEL 299
Query: 301 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 360
RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV
Sbjct: 300 RAAIDRYVQEKIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVV 359
Query: 361 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 420
VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT
Sbjct: 360 VDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGT 419
Query: 421 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 480
AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA
Sbjct: 420 AQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHA 479
Query: 481 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523
SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
Sbjct: 480 SLRLLNLVYDVTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 522
>gi|187607323 eukaryotic translation initiation factor 2B, subunit 4
delta isoform 1 [Homo sapiens]
Length = 543
Score = 1000 bits (2585), Expect = 0.0
Identities = 512/513 (99%), Positives = 512/513 (99%), Gaps = 1/513 (0%)
Query: 11 DSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQ 70
DSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQ
Sbjct: 32 DSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQ 91
Query: 71 VGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKAS 130
GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKAS
Sbjct: 92 -GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKAS 150
Query: 131 PSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQN 190
PSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQN
Sbjct: 151 PSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLPQYSRQN 210
Query: 191 SLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSR 250
SLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSR
Sbjct: 211 SLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTPPNEELSR 270
Query: 251 DLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQE 310
DLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQE
Sbjct: 271 DLVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQE 330
Query: 311 KIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGR 370
KIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGR
Sbjct: 331 KIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGR 390
Query: 371 HTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAH 430
HTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAH
Sbjct: 391 HTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAH 450
Query: 431 NVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYD 490
NVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYD
Sbjct: 451 NVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYD 510
Query: 491 VTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 523
VTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ
Sbjct: 511 VTPPELVDLVITELGMIPCSSVPVVLRVKSSDQ 543
>gi|4503503 eukaryotic translation initiation factor 2B, subunit 1
alpha, 26kDa [Homo sapiens]
Length = 305
Score = 104 bits (259), Expect = 2e-22
Identities = 63/202 (31%), Positives = 107/202 (52%), Gaps = 8/202 (3%)
Query: 311 KIVLAAQAISRFAYQKISNGDVILVYGCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGR 370
+I L+ I+ + I +G IL + S +V R+L+ A +RF V V +S+P L G+
Sbjct: 103 RISLSRNKIADLCHTFIKDGATILTHAYSRVVLRVLEAAVAAKKRFSVYVTESQPDLSGK 162
Query: 371 HTLRSLVHAGVPASYLLIPAASYVLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAH 430
++L H VP + +L A Y++ + V++GA ++ NG +++++GT Q+A+ A+A
Sbjct: 163 KMAKALCHLNVPVTVVLDAAVGYIMEKADLVIVGAEGVVENGGIINKIGTNQMAVCAKAQ 222
Query: 431 NVPVLVCCETYKFCERVQTDAFVSNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYD 490
N P V E++KF F N+ D PD + K L Q L+ + D
Sbjct: 223 NKPFYVVAESFKFVR-----LFPLNQQDVPDKFKYKAD---TLKVAQTGQDLKEEHPWVD 274
Query: 491 VTPPELVDLVITELGMIPCSSV 512
T P L+ L+ T+LG++ S+V
Sbjct: 275 YTAPSLITLLFTDLGVLTPSAV 296
>gi|7657058 eukaryotic translation initiation factor 2B, subunit 2
beta, 39kDa [Homo sapiens]
Length = 351
Score = 87.0 bits (214), Expect = 4e-17
Identities = 64/230 (27%), Positives = 114/230 (49%), Gaps = 13/230 (5%)
Query: 280 LNKEITSVGSSKREEEAKSELRAAIDRYVQEKIVL---AAQAISRFAYQKISNGDVILVY 336
L+K +TS G ++ ++L++ I + E +V + I+ A + I + +VI+
Sbjct: 109 LHKLLTSGGLNEDFSFHYAQLQSNIIEAINELLVELEGTMENIAAQALEHIHSNEVIMTI 168
Query: 337 GCSSLVSRILQEAWTEGRRFRVVVVDSRPWLEGRHTLRSLVHAGVPASYLLIPAASYVLP 396
G S V L+EA R+F V+V + P+ +G +L AG+ + + A V+
Sbjct: 169 GFSRTVEAFLKEA-ARKRKFHVIVAECAPFCQGHEMAVNLSKAGIETTVMTDAAIFAVMS 227
Query: 397 EVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNE 456
V+KV++G +LANG++ + GT LAL A+ H+ P++VC +K + + ++
Sbjct: 228 RVNKVIIGTKTILANGALRAVTGTHTLALAAKHHSTPLIVCAPMFKLSPQFPNEEDSFHK 287
Query: 457 LDDPDD-LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELVDLVITELG 505
P++ L G+ L H V+D PPEL+ L I+ +G
Sbjct: 288 FVAPEEVLPFTEGD--ILEKVSVHCP------VFDYVPPELITLFISNIG 329
>gi|72534748 translation initiation factor eIF-2B subunit
alpha/beta/delta-like protein isoform 1 [Homo sapiens]
Length = 369
Score = 68.9 bits (167), Expect = 1e-11
Identities = 69/285 (24%), Positives = 130/285 (45%), Gaps = 46/285 (16%)
Query: 252 LVNKLKPYMSFLTQCRPLSASMHNAIKFLNKEITSVGSSKREEEAKSELRAAIDRYVQEK 311
LV ++ +SFL RP + +M A + ++ V + + E E +E V+E+
Sbjct: 75 LVAFVRDKLSFLVTARPTAVNMARAAR----DLADVAAREAEREGATE------EAVRER 124
Query: 312 IVLAAQAI---------------SRFAYQKI--SNGDVILVYGCSS---------LVSRI 345
++ + + +R +++ S G V ++ C++ +
Sbjct: 125 VICCTEDMLEKDLRDNRSIGDLGARHLLERVAPSGGKVTVLTHCNTGALATAGYGTALGV 184
Query: 346 LQEAWTEGRRFRVVVVDSRPWLEG-RHTLRSLVHAGVPASYLL--IPAASYVLPEVSKVL 402
++ + GR ++RP+ +G R T LV+ +PA+ + + AA+ VS V+
Sbjct: 185 IRSLHSLGRLEHAFCTETRPYNQGARLTAFELVYEQIPATLITDSMVAAAMAHRGVSAVV 244
Query: 403 LGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFVSNELDDPDD 462
+GA ++ANG ++VGT QLA+VA+ H +P V + R++T + E +
Sbjct: 245 VGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEIIIEERPGQE 304
Query: 463 LQCKRGEHVALANWQNHASLRLLNLVYDVTPPELV-DLVITELGM 506
L G +A + + N +DVTP +L+ +ITELG+
Sbjct: 305 LTDVNGVRIAA------PGIGVWNPAFDVTPHDLITGGIITELGV 343
>gi|23943880 translation initiation factor eIF-2B subunit
alpha/beta/delta-like protein isoform 2 [Homo sapiens]
Length = 322
Score = 64.7 bits (156), Expect = 2e-10
Identities = 54/174 (31%), Positives = 88/174 (50%), Gaps = 19/174 (10%)
Query: 346 LQEAWTEGRRFRVV---------VVDSRPWLEG-RHTLRSLVHAGVPASYLL--IPAASY 393
L E W E R R + V+++RP+ +G R T LV+ +PA+ + + AA+
Sbjct: 129 LCEHWEEHTRQRELPLRGPLGGTVLETRPYNQGARLTAFELVYEQIPATLITDSMVAAAM 188
Query: 394 VLPEVSKVLLGAHALLANGSVMSRVGTAQLALVARAHNVPVLVCCETYKFCERVQTDAFV 453
VS V++GA ++ANG ++VGT QLA+VA+ H +P V + R++T +
Sbjct: 189 AHRGVSAVVVGADRVVANGDTANKVGTYQLAIVAKHHGIPFYVAAPSSSCDLRLETGKEI 248
Query: 454 SNELDDPDDLQCKRGEHVALANWQNHASLRLLNLVYDVTPPELV-DLVITELGM 506
E +L G +A + + N +DVTP +L+ +ITELG+
Sbjct: 249 IIEERPGQELTDVNGVRIAA------PGIGVWNPAFDVTPHDLITGGIITELGV 296
>gi|217035154 RCSD domain containing 1 [Homo sapiens]
Length = 416
Score = 43.1 bits (100), Expect = 6e-04
Identities = 32/137 (23%), Positives = 58/137 (42%), Gaps = 8/137 (5%)
Query: 12 SGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
+G G++ P + R ++ EK + + ++ K K + +E G + +
Sbjct: 224 AGEGVRTLGPAEKPPLRRSPSRTEKQEEDRATEEAKNGEKARRSSEEVDGQHPAQEEVPE 283
Query: 72 GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASP 131
P PE+ + G+PRE+ PAG E E+ + + ER + E+ GP +
Sbjct: 284 SPQTSGPEAENRCGSPREEKPAGE---EAEMEKATEVKGERV-----QNEEVGPEHDSQE 335
Query: 132 STAGETPSGVKRLPEYP 148
+ E + VK P P
Sbjct: 336 TKKLEEGAAVKETPHSP 352
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 42.0 bits (97), Expect = 0.001
Identities = 36/153 (23%), Positives = 74/153 (48%), Gaps = 14/153 (9%)
Query: 27 VGREMTKEEKLQLRKE--KKQQKKKRKEEKGAEPETGS-----AVSAAQCQVGPTRELPE 79
V E+T+EE+ + ++E K+++ + +E +G E ET S A S + P +E +
Sbjct: 466 VTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAK 525
Query: 80 SGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPS 139
S + +P ++ +S AE+++ +AK A+ ++A+ + P K + E S
Sbjct: 526 SPAEAKSPEKE--EAKSPAEVKSPEKAKSPAK---EEAKSPPEAKSPEKEEAKSPAEVKS 580
Query: 140 GVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKD 172
K + P ++ K PE+ + P +++
Sbjct: 581 PEK--AKSPAKEEAKSPAEAKSPEKAKSPVKEE 611
Score = 39.7 bits (91), Expect = 0.007
Identities = 36/172 (20%), Positives = 76/172 (44%), Gaps = 13/172 (7%)
Query: 9 REDSGSGMKAELPPGPGAVGREMTK---EEKLQLRKEKKQQKKKRKEEKGAEPETGSAVS 65
+E++ S + + P + +E K E K ++E K + + EK P A S
Sbjct: 535 KEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKS 594
Query: 66 AAQCQV-----GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKG 120
A+ + P +E +S + +P ++ +S AE+++ +AK + ++A+
Sbjct: 595 PAEAKSPEKAKSPVKEEAKSPAEAKSPVKE--EAKSPAEVKSPEKAKSPTK---EEAKSP 649
Query: 121 EQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKD 172
E+ P K + + S VK + P+ ++ K PE+ + P +++
Sbjct: 650 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701
Score = 39.7 bits (91), Expect = 0.007
Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 22/172 (12%)
Query: 6 VAVREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVS 65
V V+E + + P P ++ +K+E+ +KE + K + K+E E S V
Sbjct: 833 VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAP-KKEAPKPKVEEKKEPAVEKPKESKVE 891
Query: 66 AAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQ---ARKGEQ 122
A + + +++P TP ++ PA K E++ + + K++ E A K+ A+ E
Sbjct: 892 AKKEEAEDKKKVP-------TPEKEAPA---KVEVKEDAKPKEKTEVAKKEPDDAKAKEP 941
Query: 123 GGPPPK--ASPSTAGETPSGVKRLPEYPQV------DDLLLRRLVKKPERQQ 166
P K A+P K+ E P+ DD L + KP+ ++
Sbjct: 942 SKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Score = 36.6 bits (83), Expect = 0.057
Identities = 39/161 (24%), Positives = 70/161 (43%), Gaps = 10/161 (6%)
Query: 8 VREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAA 67
V+E++ S KA+ P A E K + K ++ K KEE + + S A
Sbjct: 698 VKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAK 757
Query: 68 QCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPP 127
V + + +P +K P ++K+ ++ E ++ ++A+ LK+ K + P
Sbjct: 758 TLDVKSPEAKTPAKEEARSPADKFPE-KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPK 816
Query: 128 KASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVP 168
K E S VK E PQ ++ ++ KK E ++ P
Sbjct: 817 KE------EVKSPVKE-EEKPQ--EVKVKEPPKKAEEEKAP 848
Score = 35.4 bits (80), Expect = 0.13
Identities = 41/186 (22%), Positives = 82/186 (44%), Gaps = 22/186 (11%)
Query: 8 VREDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRK-----------EEKGA 56
V+E++ S + + P + +E K + EK++ K K EK
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 57 EPETGSAVSAAQCQVGPTRELPESGIQLGTP--REKVPAGRSKAELRAERRAKQEAERAL 114
P A S + + P +E +S + +P E ++K+ ++ E + ++A+ +
Sbjct: 682 SPVKAEAKSPEKAK-SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740
Query: 115 K-QARKGEQGGPPPKAS----PSTAGETPSGVK-RLP--EYPQVDDLLLRRLVKKPERQQ 166
K +A+ E+ P KA S +TP+ + R P ++P+ ++ VK PE+ +
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800
Query: 167 VPTRKD 172
P ++D
Sbjct: 801 SPLKED 806
Score = 35.0 bits (79), Expect = 0.17
Identities = 38/174 (21%), Positives = 74/174 (42%), Gaps = 19/174 (10%)
Query: 9 REDSGSGMKAELPPGPGAVGREMTK---EEKLQLRKEKKQQKKKRKEEKGAEPETGSAVS 65
+E++ S +A+ P + +E K E K +++E K + + EK P A S
Sbjct: 589 KEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKS 648
Query: 66 AAQCQVGPTRELPESGIQLGTP---------REKVPAGRSKAELRAERRAKQEAERALKQ 116
+ + P +E +S + +P + K P KAE ++ +AK + ++
Sbjct: 649 PEKAK-SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPV---KAEAKSPEKAKSPVK---EE 701
Query: 117 ARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTR 170
A+ E+ P K + + S VK + P+ ++ K PE+ + P +
Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEK 755
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 40.8 bits (94), Expect = 0.003
Identities = 38/138 (27%), Positives = 59/138 (42%), Gaps = 20/138 (14%)
Query: 25 GAVGREMTKEEKLQLRKEKKQ--QKKKRKEEKG--------AEPETGSAVSAAQCQVGPT 74
G + R ++EE ++ + + Q+ E G + P+T AVS A Q
Sbjct: 499 GRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSP 558
Query: 75 RELPESGIQLGTPREKVPAGRS------KAELRAERRAKQEAERALKQARKGEQGGPPPK 128
+ G + G PR + PAGR+ + E+R + RA+++ R PPP
Sbjct: 559 SSAEKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPV---PPPA 615
Query: 129 ASPSTA-GETPSGVKRLP 145
A P A + P G KR P
Sbjct: 616 ADPPEARTKAPPGRKREP 633
>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
Length = 808
Score = 40.0 bits (92), Expect = 0.005
Identities = 37/137 (27%), Positives = 57/137 (41%), Gaps = 27/137 (19%)
Query: 12 SGSGMKAELP-PGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQ 70
+ G+ LP P + +KE + Q ++ +KQ+K+++K+EK E E
Sbjct: 697 TAEGLHPSLPSPTGNSTPLGSSKETRKQEKERQKQEKERQKQEKEREKE----------- 745
Query: 71 VGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKAS 130
R+ E REK R K E +++ K+ R L RK + GPP
Sbjct: 746 ----RQKQEK------EREKQEKEREKQEKERQKQEKKAQGRKLSLRRKAD--GPP---G 790
Query: 131 PSTAGETPSGVKRLPEY 147
P G+ PS R Y
Sbjct: 791 PHDGGDRPSAEARQDAY 807
>gi|17933774 transcription elongation factor A (SII)-like 2 [Homo
sapiens]
Length = 227
Score = 40.0 bits (92), Expect = 0.005
Identities = 38/154 (24%), Positives = 62/154 (40%), Gaps = 28/154 (18%)
Query: 49 KRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQ 108
K+ E +G TG V +E PES AG++K E ++ER+ K
Sbjct: 39 KKLENEGNTENTGKRVEEPL----KDKEKPES------------AGKAKGEGKSERKGKS 82
Query: 109 EAERALKQARKGEQGG-------PPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKK 161
E + K K E+GG P + P + GE S + + P DD + R+ +K
Sbjct: 83 EMQGGSKTEGKPERGGRAEGEGEPDSEREPESEGEPESETRAAGKRPAEDD-IPRKAKRK 141
Query: 162 PERQQVPTRKDYGSKVSLFSHLPQYSRQNSLTQF 195
+ K Y + H +S ++ + +F
Sbjct: 142 TNKGLAQYLKQYKEAI----HDMNFSNEDMIREF 171
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 39.3 bits (90), Expect = 0.009
Identities = 35/127 (27%), Positives = 59/127 (46%), Gaps = 6/127 (4%)
Query: 30 EMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQC---QVGPTRELPESGIQLGT 86
E E ++ +EK+ ++++ +EE+ E E + V C QVG + + T
Sbjct: 341 EKMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQSEEDGTRPQST 400
Query: 87 PREKV-PAGRSKAELRAERRAKQEAER-ALKQARKGEQGGPPPKASPSTAGE-TPSGVKR 143
+K+ +A+ AE +AK+EAE A ++A K Q K P E SGV
Sbjct: 401 SDQKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPA 460
Query: 144 LPEYPQV 150
++P+V
Sbjct: 461 TKQHPEV 467
>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
Length = 3664
Score = 39.3 bits (90), Expect = 0.009
Identities = 52/241 (21%), Positives = 85/241 (35%), Gaps = 18/241 (7%)
Query: 15 GMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPT 74
G K + P A E T E Q+ K+ E K AE E GS + G
Sbjct: 1997 GKKGKNEPKVDATRPEATTEVGPQIGV-----KESSMEPKAAEEEAGSEQKRDRKDAGTD 2051
Query: 75 RELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTA 134
+ PE+ ++ P SK++ R ++ +++ + K P+ + + A
Sbjct: 2052 KNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKS--ASLKNVDAAVSPRGAAAQA 2109
Query: 135 GETPSGVKRL----PEYPQVDDLLLRRLV-------KKPERQQVPTRKDYGSKVSLFSHL 183
GE SGV + E PQ +D L +L K+PE++ V L +
Sbjct: 2110 GERESGVVAVSPEKSESPQKEDGLSSQLKSDPVDPDKEPEKEDVSASGPSPEATQLAKQM 2169
Query: 184 PQYSRQNSLTQFMSIPSSVIHPAMVRLGLQYSQGLVSGSNARCIALLRALQQVIQDYTTP 243
+ + +S + A GL A L A+ +I D +
Sbjct: 2170 ELEQAVEHIAKLAEASASAAYKADAPEGLAPEDRDKPAHQASETELAAAIGSIINDISGE 2229
Query: 244 P 244
P
Sbjct: 2230 P 2230
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/195 (24%), Positives = 74/195 (37%), Gaps = 19/195 (9%)
Query: 22 PGP-GAVGREMTKEEKLQLRKEKKQQKKK------RKEEKGAEPETGSAVSA-----AQC 69
PGP G G ++ EE + K + K+ R++ G P T S A A
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 70 QVGPTRELPESGIQLGT--PREKVPAGRSKAELR---AERRAKQEAERALKQARKGEQGG 124
+VG R P + + T PR+ V + + A RR + A +
Sbjct: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
Query: 125 PPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLP 184
P +SP+ +G + G R P +P + ++ P Q P RKD + S P
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSP 303
Query: 185 QYSRQNSLTQFMSIP 199
+ S T+ +P
Sbjct: 304 LATPSPSGTKARPVP 318
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 38.5 bits (88), Expect = 0.015
Identities = 48/198 (24%), Positives = 74/198 (37%), Gaps = 19/198 (9%)
Query: 22 PGP-GAVGREMTKEEKLQLRKEKKQQKKK------RKEEKGAEPETGSAVSA-----AQC 69
PGP G G ++ EE + K + K+ R++ G P T S A A
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 70 QVGPTRELPESGIQLGT--PREKVPAGRSKAELR---AERRAKQEAERALKQARKGEQGG 124
+VG R P + + T PR+ V + + A RR + A +
Sbjct: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 125 PPPKASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQVPTRKDYGSKVSLFSHLP 184
P +SP+ +G + G R P +P + ++ P Q P RKD + S P
Sbjct: 237 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--QVTPPRKDAAPALGPLSSSP 294
Query: 185 QYSRQNSLTQFMSIPSSV 202
+ S S P S+
Sbjct: 295 LATPSPSAPPSPSAPPSL 312
>gi|125656165 THO complex 2 [Homo sapiens]
Length = 1593
Score = 38.1 bits (87), Expect = 0.020
Identities = 43/177 (24%), Positives = 72/177 (40%), Gaps = 19/177 (10%)
Query: 9 REDSGSGMKA------ELPPGPGAVGREMTKEEKL--QLRKEKKQQKKKRKEEKGAEPET 60
RE S G+KA P G + G + K + KEK ++K+K K+EK
Sbjct: 1231 RERSQCGVKAVNKASSTTPKGNSSNGNSGSNSNKAVKENDKEKGKEKEKEKKEKTPATTP 1290
Query: 61 GSAVSAAQCQVGPTRELPESGIQLGTPREKVP-AGRSKAELRAERRAKQE--------AE 111
+ V + P E P + +E+ P + + K + + E +AK E AE
Sbjct: 1291 EARVLGKDGKEKPKEERPNKDEKARETKERTPKSDKEKEKFKKEEKAKDEKFKTTVPNAE 1350
Query: 112 RALKQARKGEQGGPPPK--ASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPERQQ 166
Q R+ E+ + A + E G ++ P + + R + +PER+Q
Sbjct: 1351 SKSTQEREREKEPSRERDIAKEMKSKENVKGGEKTPVSGSLKSPVPRSDIPEPEREQ 1407
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 38.1 bits (87), Expect = 0.020
Identities = 27/91 (29%), Positives = 48/91 (52%), Gaps = 2/91 (2%)
Query: 33 KEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRE-LPESGIQLGTPREKV 91
+E K + ++E++++++++KEE+ E E + QVG E E + RE+
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 92 PAGRSKAELRAERRAKQEAERALKQARKGEQ 122
R K R ERR +++ ER K+ RK E+
Sbjct: 193 RKERKKERERKERRERKK-ERKKKEERKKER 222
Score = 36.2 bits (82), Expect = 0.075
Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 11/93 (11%)
Query: 33 KEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVP 92
KE+K + +KE++++KK+R+E++ E E + + +E E G +E+
Sbjct: 84 KEKKGERKKEERERKKRRREKENKEGE--------EKEKRKKKEKKERGRTSKEGKERER 135
Query: 93 AGRSKAELRAERRAK---QEAERALKQARKGEQ 122
K E R ER K +E ER K+ +K E+
Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRER 168
Score = 34.7 bits (78), Expect = 0.22
Identities = 33/139 (23%), Positives = 62/139 (44%), Gaps = 8/139 (5%)
Query: 33 KEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPREKVP 92
K+E+ + K K++++K+RK E+G + + G + + RE + G +EK
Sbjct: 60 KKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN---KEGEEKEK-- 114
Query: 93 AGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYPQVDD 152
+ K + R +K+ ER K+ RK E+ + E ++ E QV +
Sbjct: 115 -RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173
Query: 153 LLLRRLVKKPERQQVPTRK 171
R K+ ER++ R+
Sbjct: 174 KEEER--KEKERKERKKRE 190
Score = 30.4 bits (67), Expect = 4.1
Identities = 28/144 (19%), Positives = 62/144 (43%), Gaps = 15/144 (10%)
Query: 29 REMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPR 88
R+ K+E+ RK+++++++KRK E+ E + + + G + R
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERG------------KKEKKGERKKEER 95
Query: 89 EKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKRLPEYP 148
E+ R K E + K++ + ++ R ++G + E ++ E
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 149 QVDDLLLRRLVKKPERQQVPTRKD 172
+ + R+ KK ER+QV +++
Sbjct: 156 KERE---RKERKKRERKQVGEKEE 176
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 38.1 bits (87), Expect = 0.020
Identities = 38/139 (27%), Positives = 62/139 (44%), Gaps = 10/139 (7%)
Query: 29 REMTKEEKLQL-RKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRE--LPESGIQLG 85
+E +E K + RK KK++KKKR++E+ E E G + + RE + +
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180
Query: 86 TPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPSGVKR-- 143
RE+ K E + ERR K+E ++ K R+ + P + T +GV R
Sbjct: 181 KERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYR 240
Query: 144 -----LPEYPQVDDLLLRR 157
L +P ++LL R
Sbjct: 241 IFHTGLDHFPIKTNILLSR 259
Score = 37.7 bits (86), Expect = 0.026
Identities = 30/94 (31%), Positives = 43/94 (45%), Gaps = 18/94 (19%)
Query: 29 REMTKEEKLQLRKE---KKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLG 85
RE K E+ + RK KK++KK++K E+G E E R+ E Q
Sbjct: 43 REKRKREREKERKRERGKKEKKKRKKRERGKERE---------------RKRKEREKQRK 87
Query: 86 TPREKVPAGRSKAELRAERRAKQEAERALKQARK 119
REK R K + + ER+ + ER K+ RK
Sbjct: 88 ERREKERRKRKKEKKKRERKQRGRRERKKKKERK 121
Score = 31.6 bits (70), Expect = 1.8
Identities = 26/92 (28%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 29 REMTKEEKLQLRKEK-KQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTP 87
R+ KE+K + RK++ ++++KK+KE K E E Q + ++ + +
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKEREREN------KQRRERKRKKRRKKKRRKERK 148
Query: 88 REKVPAGRSKAELRAERRAKQEAERALKQARK 119
REK R K E + ++R K+E E+ ++ RK
Sbjct: 149 REK---ERGKRERKRKKRKKEEREKKRERNRK 177
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 38.1 bits (87), Expect = 0.020
Identities = 22/91 (24%), Positives = 37/91 (40%)
Query: 21 PPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPES 80
PP P E + + + + KQ + R+ ++ AE SA+ + Q R P
Sbjct: 1321 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1380
Query: 81 GIQLGTPREKVPAGRSKAELRAERRAKQEAE 111
P++ V GRSK E + +E +
Sbjct: 1381 TPSPSQPKKNVRVGRSKQAATKENDSSEEVD 1411
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 38.1 bits (87), Expect = 0.020
Identities = 41/167 (24%), Positives = 67/167 (40%), Gaps = 22/167 (13%)
Query: 12 SGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
S SG EL P A +E ++ + K K + +++ G+ PE S + ++
Sbjct: 1537 SRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDS-----KSRL 1591
Query: 72 GPTRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERAL-KQARKGEQG---GPPP 127
P R S ++ P +S ++ E +A A RAL +++R G GP P
Sbjct: 1592 SPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKA--PAPRALPRRSRSGSSSKGRGPSP 1649
Query: 128 KASPSTAGETPSGVKRLPEYPQVDDLLLRRLVKKPE---RQQVPTRK 171
+ S ST PE+P R PE + + P R+
Sbjct: 1650 EGSSSTESS--------PEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688
Score = 32.7 bits (73), Expect = 0.83
Identities = 25/119 (21%), Positives = 51/119 (42%), Gaps = 6/119 (5%)
Query: 21 PPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPES 80
PP P ++ RE + KQ+KKK+K+++G E+ S + + ES
Sbjct: 167 PPKPYSLVRESSSSRS----PTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222
Query: 81 GIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARKGEQGGPPPKASPSTAGETPS 139
+ + + P +SK + + ++R + + ++R+ + AS S + S
Sbjct: 223 --ESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS 279
Score = 30.0 bits (66), Expect = 5.4
Identities = 28/132 (21%), Positives = 46/132 (34%), Gaps = 11/132 (8%)
Query: 22 PGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESG 81
P P R + + K ++ R S + + + TR SG
Sbjct: 1733 PEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSG 1792
Query: 82 IQLGTPREKVPAGRSKAELRAERR----------AKQEAERALKQARKGEQGGPPPKASP 131
T R + RS++ + RR A+QE+ R + R+G PP
Sbjct: 1793 SSQSTSRRR-QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKR 1851
Query: 132 STAGETPSGVKR 143
S + +P+ KR
Sbjct: 1852 SRSRTSPAPWKR 1863
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 37.7 bits (86), Expect = 0.026
Identities = 25/91 (27%), Positives = 44/91 (48%), Gaps = 14/91 (15%)
Query: 29 REMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTPR 88
++ TKE + + KE++++K+KRK +K E E RE E +
Sbjct: 43 KKKTKETEKRKEKEEEEKKRKRKRKKKKEEE--------------EREEEEEEEEEEKEE 88
Query: 89 EKVPAGRSKAELRAERRAKQEAERALKQARK 119
E+ GR + + + RR ++E E+ K+ RK
Sbjct: 89 EEKEEGRRRKKKKKRRRKEEEEEKKKKRRRK 119
>gi|58761546 amine oxidase (flavin containing) domain 2 isoform b
[Homo sapiens]
Length = 852
Score = 37.7 bits (86), Expect = 0.026
Identities = 42/151 (27%), Positives = 60/151 (39%), Gaps = 39/151 (25%)
Query: 14 SGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAV--SAAQCQV 71
+G+ GPGAVG ++ ++KE A P G A +A Q
Sbjct: 42 AGLSGPAEVGPGAVG----------------ERTPRKKEPPRASPPGGLAEPPGSAGPQA 85
Query: 72 GPTRELPESGIQLGTPREKVPAGR-------SKAELR---------AERRAKQEAERALK 115
GPT +P S + T + P GR +K E R +E E ER K
Sbjct: 86 GPT-VVPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAK 144
Query: 116 QARKGEQGGPPPKASPSTAGET----PSGVK 142
++ + PPP+A P E+ PSGV+
Sbjct: 145 AEKEKKLPPPPPQAPPEEENESEPEEPSGVE 175
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 37.7 bits (86), Expect = 0.026
Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 11/138 (7%)
Query: 14 SGMKAELPPGPGAVGREMTKEE--KLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
S K P PG G + K + K + + ++ +EE A+ + +
Sbjct: 304 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 72 GPTRELPESGIQLGTPREKVPA------GRSKAELRA---ERRAKQEAERALKQARKGEQ 122
P +E P G PR+ PA G+ + + R+ E + +EA A+ A+
Sbjct: 364 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 423
Query: 123 GGPPPKASPSTAGETPSG 140
G P ST G P G
Sbjct: 424 GKSPQVKPASTMGMGPLG 441
Score = 31.2 bits (69), Expect = 2.4
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 4/105 (3%)
Query: 34 EEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTP-REKVP 92
E+ LQ+R K + P + A+Q + G E ES + + E+ P
Sbjct: 218 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 277
Query: 93 AGRSKAELRAERRAKQ---EAERALKQARKGEQGGPPPKASPSTA 134
A ++ + +A + Q + A + RKG PP K P+ A
Sbjct: 278 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVA 322
Score = 30.8 bits (68), Expect = 3.2
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 25/135 (18%)
Query: 18 AELPPGPGAV---GREMTKEEKLQLRKEKKQQKKKRKEEKG--------AEPETGSAVS- 65
A P G + G+ +T + + R K + R + + P G AV+
Sbjct: 720 ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 779
Query: 66 AAQCQVGP------TRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARK 119
AAQ Q GP + E +S + T + P+G++ ++RA +E+ R K
Sbjct: 780 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH-QIRAALAPAKESPR------K 832
Query: 120 GEQGGPPPKASPSTA 134
G PP K PS A
Sbjct: 833 GAAPTPPGKTGPSAA 847
Score = 29.3 bits (64), Expect = 9.2
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 19 ELPPGPGAV-----GREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQ 68
EL G G V +K+EK + K KK ++KK K++K + T + S +Q
Sbjct: 1344 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1398
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 37.7 bits (86), Expect = 0.026
Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 11/138 (7%)
Query: 14 SGMKAELPPGPGAVGREMTKEE--KLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
S K P PG G + K + K + + ++ +EE A+ + +
Sbjct: 381 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 72 GPTRELPESGIQLGTPREKVPA------GRSKAELRA---ERRAKQEAERALKQARKGEQ 122
P +E P G PR+ PA G+ + + R+ E + +EA A+ A+
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 123 GGPPPKASPSTAGETPSG 140
G P ST G P G
Sbjct: 501 GKSPQVKPASTMGMGPLG 518
Score = 35.8 bits (81), Expect = 0.098
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 4/129 (3%)
Query: 10 EDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQC 69
E S G ++E G + E+ LQ+R K + P + A+Q
Sbjct: 271 ESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 70 QVGPTRELPESGIQLGTP-REKVPAGRSKAELRAERRAKQ---EAERALKQARKGEQGGP 125
+ G E ES + + E+ PA ++ + +A + Q + A + RKG P
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 126 PPKASPSTA 134
P K P+ A
Sbjct: 391 PGKTGPAVA 399
Score = 30.8 bits (68), Expect = 3.2
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 25/135 (18%)
Query: 18 AELPPGPGAV---GREMTKEEKLQLRKEKKQQKKKRKEEKG--------AEPETGSAVS- 65
A P G + G+ +T + + R K + R + + P G AV+
Sbjct: 797 ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 856
Query: 66 AAQCQVGP------TRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARK 119
AAQ Q GP + E +S + T + P+G++ ++RA +E+ R K
Sbjct: 857 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH-QIRAALAPAKESPR------K 909
Query: 120 GEQGGPPPKASPSTA 134
G PP K PS A
Sbjct: 910 GAAPTPPGKTGPSAA 924
Score = 29.3 bits (64), Expect = 9.2
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 19 ELPPGPGAV-----GREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQ 68
EL G G V +K+EK + K KK ++KK K++K + T + S +Q
Sbjct: 1383 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1437
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 37.7 bits (86), Expect = 0.026
Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 11/138 (7%)
Query: 14 SGMKAELPPGPGAVGREMTKEE--KLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
S K P PG G + K + K + + ++ +EE A+ + +
Sbjct: 381 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 72 GPTRELPESGIQLGTPREKVPA------GRSKAELRA---ERRAKQEAERALKQARKGEQ 122
P +E P G PR+ PA G+ + + R+ E + +EA A+ A+
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 123 GGPPPKASPSTAGETPSG 140
G P ST G P G
Sbjct: 501 GKSPQVKPASTMGMGPLG 518
Score = 35.8 bits (81), Expect = 0.098
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 4/129 (3%)
Query: 10 EDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQC 69
E S G ++E G + E+ LQ+R K + P + A+Q
Sbjct: 271 ESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 70 QVGPTRELPESGIQLGTP-REKVPAGRSKAELRAERRAKQ---EAERALKQARKGEQGGP 125
+ G E ES + + E+ PA ++ + +A + Q + A + RKG P
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 126 PPKASPSTA 134
P K P+ A
Sbjct: 391 PGKTGPAVA 399
Score = 30.8 bits (68), Expect = 3.2
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 25/135 (18%)
Query: 18 AELPPGPGAV---GREMTKEEKLQLRKEKKQQKKKRKEEKG--------AEPETGSAVS- 65
A P G + G+ +T + + R K + R + + P G AV+
Sbjct: 797 ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 856
Query: 66 AAQCQVGP------TRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARK 119
AAQ Q GP + E +S + T + P+G++ ++RA +E+ R K
Sbjct: 857 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH-QIRAALAPAKESPR------K 909
Query: 120 GEQGGPPPKASPSTA 134
G PP K PS A
Sbjct: 910 GAAPTPPGKTGPSAA 924
Score = 29.3 bits (64), Expect = 9.2
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 19 ELPPGPGAV-----GREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQ 68
EL G G V +K+EK + K KK ++KK K++K + T + S +Q
Sbjct: 1420 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1474
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 37.7 bits (86), Expect = 0.026
Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 11/138 (7%)
Query: 14 SGMKAELPPGPGAVGREMTKEE--KLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
S K P PG G + K + K + + ++ +EE A+ + +
Sbjct: 304 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 363
Query: 72 GPTRELPESGIQLGTPREKVPA------GRSKAELRA---ERRAKQEAERALKQARKGEQ 122
P +E P G PR+ PA G+ + + R+ E + +EA A+ A+
Sbjct: 364 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 423
Query: 123 GGPPPKASPSTAGETPSG 140
G P ST G P G
Sbjct: 424 GKSPQVKPASTMGMGPLG 441
Score = 31.2 bits (69), Expect = 2.4
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 4/105 (3%)
Query: 34 EEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQVGPTRELPESGIQLGTP-REKVP 92
E+ LQ+R K + P + A+Q + G E ES + + E+ P
Sbjct: 218 EKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETP 277
Query: 93 AGRSKAELRAERRAKQ---EAERALKQARKGEQGGPPPKASPSTA 134
A ++ + +A + Q + A + RKG PP K P+ A
Sbjct: 278 AAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVA 322
Score = 30.8 bits (68), Expect = 3.2
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 25/135 (18%)
Query: 18 AELPPGPGAV---GREMTKEEKLQLRKEKKQQKKKRKEEKG--------AEPETGSAVS- 65
A P G + G+ +T + + R K + R + + P G AV+
Sbjct: 720 ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 779
Query: 66 AAQCQVGP------TRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARK 119
AAQ Q GP + E +S + T + P+G++ ++RA +E+ R K
Sbjct: 780 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH-QIRAALAPAKESPR------K 832
Query: 120 GEQGGPPPKASPSTA 134
G PP K PS A
Sbjct: 833 GAAPTPPGKTGPSAA 847
Score = 29.3 bits (64), Expect = 9.2
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 19 ELPPGPGAV-----GREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQ 68
EL G G V +K+EK + K KK ++KK K++K + T + S +Q
Sbjct: 1343 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1397
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 37.7 bits (86), Expect = 0.026
Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 11/138 (7%)
Query: 14 SGMKAELPPGPGAVGREMTKEE--KLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
S K P PG G + K + K + + ++ +EE A+ + +
Sbjct: 381 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 72 GPTRELPESGIQLGTPREKVPA------GRSKAELRA---ERRAKQEAERALKQARKGEQ 122
P +E P G PR+ PA G+ + + R+ E + +EA A+ A+
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 123 GGPPPKASPSTAGETPSG 140
G P ST G P G
Sbjct: 501 GKSPQVKPASTMGMGPLG 518
Score = 35.8 bits (81), Expect = 0.098
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 4/129 (3%)
Query: 10 EDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQC 69
E S G ++E G + E+ LQ+R K + P + A+Q
Sbjct: 271 ESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 70 QVGPTRELPESGIQLGTP-REKVPAGRSKAELRAERRAKQ---EAERALKQARKGEQGGP 125
+ G E ES + + E+ PA ++ + +A + Q + A + RKG P
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 126 PPKASPSTA 134
P K P+ A
Sbjct: 391 PGKTGPAVA 399
Score = 30.8 bits (68), Expect = 3.2
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 25/135 (18%)
Query: 18 AELPPGPGAV---GREMTKEEKLQLRKEKKQQKKKRKEEKG--------AEPETGSAVS- 65
A P G + G+ +T + + R K + R + + P G AV+
Sbjct: 797 ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 856
Query: 66 AAQCQVGP------TRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARK 119
AAQ Q GP + E +S + T + P+G++ ++RA +E+ R K
Sbjct: 857 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH-QIRAALAPAKESPR------K 909
Query: 120 GEQGGPPPKASPSTA 134
G PP K PS A
Sbjct: 910 GAAPTPPGKTGPSAA 924
Score = 29.3 bits (64), Expect = 9.2
Identities = 18/55 (32%), Positives = 28/55 (50%), Gaps = 5/55 (9%)
Query: 19 ELPPGPGAV-----GREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQ 68
EL G G V +K+EK + K KK ++KK K++K + T + S +Q
Sbjct: 1382 ELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQ 1436
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 37.7 bits (86), Expect = 0.026
Identities = 33/138 (23%), Positives = 53/138 (38%), Gaps = 11/138 (7%)
Query: 14 SGMKAELPPGPGAVGREMTKEE--KLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQCQV 71
S K P PG G + K + K + + ++ +EE A+ + +
Sbjct: 381 SPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAAS 440
Query: 72 GPTRELPESGIQLGTPREKVPA------GRSKAELRA---ERRAKQEAERALKQARKGEQ 122
P +E P G PR+ PA G+ + + R+ E + +EA A+ A+
Sbjct: 441 APAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPL 500
Query: 123 GGPPPKASPSTAGETPSG 140
G P ST G P G
Sbjct: 501 GKSPQVKPASTMGMGPLG 518
Score = 35.8 bits (81), Expect = 0.098
Identities = 31/129 (24%), Positives = 51/129 (39%), Gaps = 4/129 (3%)
Query: 10 EDSGSGMKAELPPGPGAVGREMTKEEKLQLRKEKKQQKKKRKEEKGAEPETGSAVSAAQC 69
E S G ++E G + E+ LQ+R K + P + A+Q
Sbjct: 271 ESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQT 330
Query: 70 QVGPTRELPESGIQLGTP-REKVPAGRSKAELRAERRAKQ---EAERALKQARKGEQGGP 125
+ G E ES + + E+ PA ++ + +A + Q + A + RKG P
Sbjct: 331 KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAP 390
Query: 126 PPKASPSTA 134
P K P+ A
Sbjct: 391 PGKTGPAVA 399
Score = 30.8 bits (68), Expect = 3.2
Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 25/135 (18%)
Query: 18 AELPPGPGAV---GREMTKEEKLQLRKEKKQQKKKRKEEKG--------AEPETGSAVS- 65
A P G + G+ +T + + R K + R + + P G AV+
Sbjct: 797 ARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVAT 856
Query: 66 AAQCQVGP------TRELPESGIQLGTPREKVPAGRSKAELRAERRAKQEAERALKQARK 119
AAQ Q GP + E +S + T + P+G++ ++RA +E+ R K
Sbjct: 857 AAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTH-QIRAALAPAKESPR------K 909
Query: 120 GEQGGPPPKASPSTA 134
G PP K PS A
Sbjct: 910 GAAPTPPGKTGPSAA 924
>gi|217035121 HMG-BOX transcription factor BBX isoform 1 [Homo
sapiens]
Length = 941
Score = 37.4 bits (85), Expect = 0.034
Identities = 37/150 (24%), Positives = 63/150 (42%), Gaps = 36/150 (24%)
Query: 31 MTKEEKLQLRKEKKQQ----------KKKRKEEKGAEPETGSAVSAAQCQVGPTRELPES 80
+ K EKL+ +K+K + KK K+ + +E + S + + + +
Sbjct: 444 LNKPEKLKKKKKKSKMDRHGNDKSTPKKTCKKRQSSESDIESVIYTIEAVAKGDWGIEKL 503
Query: 81 GIQLGTPREKVPAGRS-------------KAELRAERRAKQEAERALKQARKGEQGGPPP 127
G TPR+KV S K + R ++ +K+++ K++R PP
Sbjct: 504 G---DTPRKKVRTSSSGKGSILDAKPPKKKVKSREKKMSKEKSSDTTKESR------PPD 554
Query: 128 ----KASPSTAGETPSGVKRLPEYPQVDDL 153
AS + +GETP G+K P P D L
Sbjct: 555 FISISASKNISGETPEGIKAEPLTPMEDAL 584
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.369
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,079,944
Number of Sequences: 37866
Number of extensions: 1032000
Number of successful extensions: 9709
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 329
Number of HSP's that attempted gapping in prelim test: 8109
Number of HSP's gapped (non-prelim): 1471
length of query: 523
length of database: 18,247,518
effective HSP length: 107
effective length of query: 416
effective length of database: 14,195,856
effective search space: 5905476096
effective search space used: 5905476096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.