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Search of human proteins with 7706739
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706739 transducer of ERBB2, 2 [Homo sapiens]
(344 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706739 transducer of ERBB2, 2 [Homo sapiens] 693 0.0
gi|5032187 transducer of ERBB2, 1 [Homo sapiens] 363 e-100
gi|4502473 B-cell translocation protein 1 [Homo sapiens] 110 1e-24
gi|5802988 B-cell translocation gene 2 [Homo sapiens] 102 4e-22
gi|28872722 B-cell translocation gene 3 isoform b [Homo sapiens] 83 4e-16
gi|195963406 B-cell translocation gene 3 isoform a [Homo sapiens] 75 9e-14
gi|8923958 B-cell translocation gene 4 [Homo sapiens] 71 2e-12
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 42 8e-04
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 39 0.005
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 39 0.005
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 39 0.005
gi|22902136 osterix [Homo sapiens] 39 0.007
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 38 0.015
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 37 0.020
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens] 37 0.026
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 37 0.034
gi|157694497 zinc finger and BTB domain containing 10 isoform b ... 37 0.034
gi|157694499 zinc finger and BTB domain containing 10 isoform a ... 37 0.034
gi|55956910 meningioma 1 [Homo sapiens] 35 0.098
gi|126090909 engrailed homeobox 1 [Homo sapiens] 34 0.17
gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens] 34 0.17
gi|22547204 hairless protein isoform a [Homo sapiens] 34 0.17
gi|22547207 hairless protein isoform b [Homo sapiens] 34 0.17
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 34 0.17
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens] 34 0.22
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens] 34 0.22
gi|89276766 trophinin isoform 5 [Homo sapiens] 34 0.22
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 34 0.22
gi|109255251 loricrin [Homo sapiens] 34 0.22
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 34 0.22
>gi|7706739 transducer of ERBB2, 2 [Homo sapiens]
Length = 344
Score = 693 bits (1788), Expect = 0.0
Identities = 344/344 (100%), Positives = 344/344 (100%)
Query: 1 MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHI 60
MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHI
Sbjct: 1 MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHI 60
Query: 61 GEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSEGC 120
GEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSEGC
Sbjct: 61 GEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSEGC 120
Query: 121 GAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTAS 180
GAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTAS
Sbjct: 121 GAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTAS 180
Query: 181 FAATKFGSTKMKKGGGAASGGGVASSGAGGQQPPQQPRMARSPTNSLLKHKSLSLSMHSL 240
FAATKFGSTKMKKGGGAASGGGVASSGAGGQQPPQQPRMARSPTNSLLKHKSLSLSMHSL
Sbjct: 181 FAATKFGSTKMKKGGGAASGGGVASSGAGGQQPPQQPRMARSPTNSLLKHKSLSLSMHSL 240
Query: 241 NFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFD 300
NFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFD
Sbjct: 241 NFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFD 300
Query: 301 MAQVFGGGANSLFLEKTPFVEGLSYNLNTMQYPSQQFQPVVLAN 344
MAQVFGGGANSLFLEKTPFVEGLSYNLNTMQYPSQQFQPVVLAN
Sbjct: 301 MAQVFGGGANSLFLEKTPFVEGLSYNLNTMQYPSQQFQPVVLAN 344
>gi|5032187 transducer of ERBB2, 1 [Homo sapiens]
Length = 345
Score = 363 bits (932), Expect = e-100
Identities = 206/372 (55%), Positives = 245/372 (65%), Gaps = 60/372 (16%)
Query: 1 MQLEIKVALNFIISYLYNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHI 60
MQLEI+VALNFIISYLYNKLPRRR ++FGEELERLLKKKYEGHWYPEKP KGSGFRC+HI
Sbjct: 1 MQLEIQVALNFIISYLYNKLPRRRVNIFGEELERLLKKKYEGHWYPEKPYKGSGFRCIHI 60
Query: 61 GEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSEGC 120
GE VDPV+E A+K SGL ++DVR N+P++LSVWIDPFEVSYQIGEKG VKVLY+DD+
Sbjct: 61 GEKVDPVIEQASKESGLDIDDVRGNLPQDLSVWIDPFEVSYQIGEKGPVKVLYVDDNNEN 120
Query: 121 GAPELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSP--SPTFIPRSAQPITFTT 178
G ELDKEIK+SFNP+AQVF+PI SS+S+SPSP FG S SPTF+PRS QP+TFTT
Sbjct: 121 GC-ELDKEIKNSFNPEAQVFMPISDPASSVSSSPSPPFGHSAAVSPTFMPRSTQPLTFTT 179
Query: 179 ASFAATKFGSTKMKKGGGAASGGGVASSGAGGQQPPQQPRMARSPTNSLLKHKSLSLSMH 238
A+FAATKFGSTKMK +SG + P N LLK K++S SMH
Sbjct: 180 ATFAATKFGSTKMK------------NSGRSNKVARTSPINLGLNVNDLLKQKAISSSMH 227
Query: 239 SLNFITAN------------------PAPQSQ-------LSPNAKEFVYNGGGSPSLFFD 273
SL + P PQ Q LSPNAKEF+ F
Sbjct: 228 SLYGLGLGSQQQPQQQQQPAQPPPPPPPPQQQQQQKTSALSPNAKEFI----------FP 277
Query: 274 AADGQGSGTPGPFGGSGAGTCN----SSSFDMAQVFGGGANSLFLEKTPFVEGLSYNLNT 329
GQGS T G F G + S++FD+ +GG L + FV+GL+++LN
Sbjct: 278 NMQGQGSSTNGMFPGDSPLNLSPLQYSNAFDVFAAYGG------LNEKSFVDGLNFSLNN 331
Query: 330 MQYPSQQFQPVV 341
MQY +QQFQPV+
Sbjct: 332 MQYSNQQFQPVM 343
>gi|4502473 B-cell translocation protein 1 [Homo sapiens]
Length = 171
Score = 110 bits (276), Expect = 1e-24
Identities = 50/112 (44%), Positives = 77/112 (68%), Gaps = 2/112 (1%)
Query: 4 EIKVALNFIISYLYNK--LPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIG 61
EI A++FI +L K R+ F + L+ LL + Y+ HW+PEKP KGSG+RC+ I
Sbjct: 14 EIAAAVSFISKFLRTKGLTSERQLQTFSQSLQELLAEHYKHHWFPEKPCKGSGYRCIRIN 73
Query: 62 EMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLY 113
+DP++ AA+R GL+ +++ +P EL++W+DP+EVSY+IGE G++ VLY
Sbjct: 74 HKMDPLIGQAAQRIGLSSQELFRLLPSELTLWVDPYEVSYRIGEDGSICVLY 125
>gi|5802988 B-cell translocation gene 2 [Homo sapiens]
Length = 158
Score = 102 bits (255), Expect = 4e-22
Identities = 46/112 (41%), Positives = 72/112 (64%), Gaps = 2/112 (1%)
Query: 4 EIKVALNFIISYLYNK--LPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIG 61
EI A+ F+ S L + + +R +F L+ L + Y+ HW+PEKP KGSG+RC+ I
Sbjct: 12 EIAAAVGFLSSLLRTRGCVSEQRLKVFSGALQEALTEHYKHHWFPEKPSKGSGYRCIRIN 71
Query: 62 EMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLY 113
+DP++ A + GL+ + +P EL++W+DP+EVSY+IGE G++ VLY
Sbjct: 72 HKMDPIISRVASQIGLSQPQLHQLLPSELTLWVDPYEVSYRIGEDGSICVLY 123
>gi|28872722 B-cell translocation gene 3 isoform b [Homo sapiens]
Length = 252
Score = 82.8 bits (203), Expect = 4e-16
Identities = 45/160 (28%), Positives = 83/160 (51%), Gaps = 9/160 (5%)
Query: 17 YNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIG--EMVDPVVELAAKR 74
++KL + + F E+L +L++KY+ HWYPEKP KG +RC+ + + VDP V A +
Sbjct: 19 HDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACEN 78
Query: 75 SGLAVEDVRANVPEELSVWIDPFEVSYQIGEKGAVKVLYLDDSEGCGAPELDKEIKSSFN 134
S + D+ +P+EL++W+DP EV + GEK ++ +++ E+ +++ + +
Sbjct: 79 SCILYSDL--GLPKELTLWVDPCEVCCRYGEKNNAFIVASFENKDENKDEISRKVTRALD 136
Query: 135 PDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPI 174
V S S+ S P+ + +A P+
Sbjct: 137 K-----VTSDYHSGSSSSDEETSKEMEVKPSSVTAAASPV 171
>gi|195963406 B-cell translocation gene 3 isoform a [Homo sapiens]
Length = 296
Score = 75.1 bits (183), Expect = 9e-14
Identities = 34/85 (40%), Positives = 55/85 (64%), Gaps = 4/85 (4%)
Query: 17 YNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCVHIG--EMVDPVVELAAKR 74
++KL + + F E+L +L++KY+ HWYPEKP KG +RC+ + + VDP V A +
Sbjct: 19 HDKLKKEAVERFAEKLTLILQEKYKNHWYPEKPSKGQAYRCIRVNKFQRVDPDVLKACEN 78
Query: 75 SGLAVEDVRANVPEELSVWIDPFEV 99
S + D+ +P+EL++W+DP EV
Sbjct: 79 SCILYSDL--GLPKELTLWVDPCEV 101
>gi|8923958 B-cell translocation gene 4 [Homo sapiens]
Length = 223
Score = 70.9 bits (172), Expect = 2e-12
Identities = 37/110 (33%), Positives = 64/110 (58%), Gaps = 6/110 (5%)
Query: 1 MQLEIKVALNFIISYL--YNKLPRRRADLFGEELERLLKKKYEGHWYPEKPLKGSGFRCV 58
M+ EI + F+ + ++KL +++ + F E+L +L + Y HW+ + P KG FRC+
Sbjct: 1 MRDEIATTVFFVTRLVKKHDKLSKQQIEDFAEKLMTILFETYRSHWHSDCPSKGQAFRCI 60
Query: 59 HI--GEMVDPVVELAAKRSGLAVEDVRANVPEELSVWIDPFEVSYQIGEK 106
I + DP++E A S V+ +P+E+++W+DPFEV + GEK
Sbjct: 61 RINNNQNKDPILERACVESN--VDFSHLGLPKEMTIWVDPFEVCCRYGEK 108
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 42.0 bits (97), Expect = 8e-04
Identities = 57/218 (26%), Positives = 79/218 (36%), Gaps = 49/218 (22%)
Query: 141 VPIGSQDSSLSNSPSPSF-GQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAAS 199
+P GS + SP PS+ G +P P F QP + A + FGS+
Sbjct: 685 IPFGSS----AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALAPS-FGSS-------FTF 732
Query: 200 GGGVASSGAGGQQPPQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKE 259
G A + A PP ++ + + + H + HS + A + + +
Sbjct: 733 GNSAAPAAAPTPAPPSMIKVVPAYVPTPI-HPIFGGATHSAFGLKATASAFGAPASSQPA 791
Query: 260 FVYNGGGSPSLFFDAADGQGSG------------------TPGP--FGGSGA-------- 291
F GGS ++FF AA G G TP P FGGS A
Sbjct: 792 F----GGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFG 847
Query: 292 ---GTCNSSSFDMAQVFGGGANSLFLEKTPFVEGLSYN 326
T SS+ A FG G + TPF GL N
Sbjct: 848 INVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQN 885
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 148 SSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSG 207
SS ++SP+PS G P + P +P +A+ AA ST GGG + GGG +S
Sbjct: 34 SSATSSPAPSIG--PPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGN 91
Query: 208 AGG 210
GG
Sbjct: 92 GGG 94
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 148 SSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSG 207
SS ++SP+PS G P + P +P +A+ AA ST GGG + GGG +S
Sbjct: 34 SSATSSPAPSIG--PPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGN 91
Query: 208 AGG 210
GG
Sbjct: 92 GGG 94
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 2/63 (3%)
Query: 148 SSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSG 207
SS ++SP+PS G P + P +P +A+ AA ST GGG + GGG +S
Sbjct: 34 SSATSSPAPSIG--PPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGN 91
Query: 208 AGG 210
GG
Sbjct: 92 GGG 94
>gi|22902136 osterix [Homo sapiens]
Length = 431
Score = 38.9 bits (89), Expect = 0.007
Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 11/130 (8%)
Query: 194 GGGAASGGGVASS-GAGGQQPPQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQ 252
GGG G G+ + G QPP P++ P++ + + + H L + PQ
Sbjct: 169 GGGQGQGDGLQGTLPTGPAQPPLNPQLPTYPSDFAPLNPAPYPAPHLLQPGPQHVLPQDV 228
Query: 253 LSP----NAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFDMAQVFGGG 308
P N+ + +GG P G +G G +GGSGAG + + ++ G
Sbjct: 229 YKPKAVGNSGQLEGSGGAKPPR------GASTGGSGGYGGSGAGRSSCDCPNCQELERLG 282
Query: 309 ANSLFLEKTP 318
A + L K P
Sbjct: 283 AAAAGLRKKP 292
>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
sapiens]
Length = 834
Score = 37.7 bits (86), Expect = 0.015
Identities = 58/217 (26%), Positives = 77/217 (35%), Gaps = 46/217 (21%)
Query: 141 VPIGSQDSSLSNSPSPSF-GQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAAS 199
+P GS + SP PS+ G +P P F QP + + FGS+
Sbjct: 534 IPFGSS----AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPS-FGSS-------FTF 581
Query: 200 GGGVASSGAGGQQPPQQPRMARS-------PTNSLLKHKSLSLSMHSLNFITANPAPQSQ 252
G A + A PP ++ + PT H + L + F PA SQ
Sbjct: 582 GNSAAPAAAPTPAPPSMIKIVPAHVPTPIQPTFGGATHSAFGLKATASAF--GAPA-SSQ 638
Query: 253 LSPNAKEFVYNGGGSPSLFFDAADGQ----------GSGTPGPF--GGSGA--------- 291
+ V++ G + S F A GS TP PF GGS A
Sbjct: 639 PAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGI 698
Query: 292 --GTCNSSSFDMAQVFGGGANSLFLEKTPFVEGLSYN 326
T SS+ A FG G + TPF GL N
Sbjct: 699 NVATPGSSATTGAFSFGAGQSGSTATSTPFAGGLGQN 735
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 37.4 bits (85), Expect = 0.020
Identities = 49/187 (26%), Positives = 68/187 (36%), Gaps = 25/187 (13%)
Query: 143 IGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGG 202
+ + S S+ F QS S S+ PI + A+ T S KK G +
Sbjct: 239 VATSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPAN--CTTENSEDDKKRGRSTDSEV 296
Query: 203 VASSGAGGQQP------PQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPN 256
S G +P PQ P + + + S + N + A AP S L P
Sbjct: 297 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPK 356
Query: 257 AKEFVYNGGGSPSLFFDAA-----DGQGSGTPGP---------FGGSGAGTCNSSSFDMA 302
A + G+P+ + A G + P P GGSG G +SSS A
Sbjct: 357 ASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSA 416
Query: 303 QVFGGGA 309
GGGA
Sbjct: 417 ---GGGA 420
Score = 30.0 bits (66), Expect = 3.2
Identities = 40/146 (27%), Positives = 58/146 (39%), Gaps = 22/146 (15%)
Query: 153 SPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASS------ 206
SP+PS S +P ++ P + S + S + GGG SGGG +SS
Sbjct: 358 SPAPSHN-SGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSA 416
Query: 207 --GAGGQQ--PPQQPRMARSPTN-SLLKHKSLSLSMHSLNFITA--NPAPQSQLSPNAKE 259
GAG Q +A SP +L + S +L + NP P + P+A
Sbjct: 417 GGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAA 476
Query: 260 FVYNGGGSPSLFFDAADGQGSGTPGP 285
GG +P G G+ + GP
Sbjct: 477 PTGAGGVAP--------GSGNNSGGP 494
>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
Length = 987
Score = 37.0 bits (84), Expect = 0.026
Identities = 60/214 (28%), Positives = 77/214 (35%), Gaps = 38/214 (17%)
Query: 141 VPIGSQDSSLSNSPSPSF-GQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAAS 199
+P GS + SP PS+ G +P P F QP + + FGS+ G AA
Sbjct: 685 IPFGSS----AKSPLPSYPGANPQPAFGAAEGQPPGAAKPALTPS-FGSS-FTFGNSAAP 738
Query: 200 GGGVASSGAGGQQ----PPQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSP 255
A + A P P + PT H + L + F PA SQ +
Sbjct: 739 APATAPTPAPASTIKIVPAHVPTPIQ-PTFGGATHSAFGLKATASAF--GAPA-SSQPAF 794
Query: 256 NAKEFVYNGGGSPSLFFDAADGQ----------GSGTPGPF--GGSGA-----------G 292
V++ G + S F A GS TP PF GGS A
Sbjct: 795 GGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVA 854
Query: 293 TCNSSSFDMAQVFGGGANSLFLEKTPFVEGLSYN 326
T SS+ A FG G + TPF GL N
Sbjct: 855 TPGSSATTGAFSFGAGQSGSTATSTPFTGGLGQN 888
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 36.6 bits (83), Expect = 0.034
Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 1/89 (1%)
Query: 122 APELDKEIKSSFNPDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASF 181
AP + S+ + A + S+ + PS G +P S+Q A+
Sbjct: 346 APAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAA- 404
Query: 182 AATKFGSTKMKKGGGAASGGGVASSGAGG 210
AA GS GGG GGG +GAGG
Sbjct: 405 AAAALGSRGGGGGGGGGGGGGGGGAGAGG 433
>gi|157694497 zinc finger and BTB domain containing 10 isoform b
[Homo sapiens]
Length = 847
Score = 36.6 bits (83), Expect = 0.034
Identities = 40/133 (30%), Positives = 53/133 (39%), Gaps = 35/133 (26%)
Query: 193 KGGG--AASGGGVASSGAGGQQ---PPQ-QPRM-------ARSPTNSLLKHKSLSLSMHS 239
+GGG ASGGG ++ AGG+ PPQ QPR A P N + + L
Sbjct: 14 RGGGLVTASGGGSTNNNAGGEASAWPPQPQPRQPPPPAPPALQPPNGRGADEEVELEGLE 73
Query: 240 LNFITANPAPQSQLSPNAKEFV--YNGGGSPSLFFDAADGQGSGTPGPF----------- 286
+ A+ P + + AKE + + GG SL G G GP
Sbjct: 74 PQDLEASAGPAAGAAEEAKELLLPQDAGGPTSL--------GGGAGGPLLAERNRRTLAF 125
Query: 287 -GGSGAGTCNSSS 298
GG G G N+ S
Sbjct: 126 RGGGGGGLGNNGS 138
>gi|157694499 zinc finger and BTB domain containing 10 isoform a
[Homo sapiens]
Length = 871
Score = 36.6 bits (83), Expect = 0.034
Identities = 40/133 (30%), Positives = 53/133 (39%), Gaps = 35/133 (26%)
Query: 193 KGGG--AASGGGVASSGAGGQQ---PPQ-QPRM-------ARSPTNSLLKHKSLSLSMHS 239
+GGG ASGGG ++ AGG+ PPQ QPR A P N + + L
Sbjct: 14 RGGGLVTASGGGSTNNNAGGEASAWPPQPQPRQPPPPAPPALQPPNGRGADEEVELEGLE 73
Query: 240 LNFITANPAPQSQLSPNAKEFV--YNGGGSPSLFFDAADGQGSGTPGPF----------- 286
+ A+ P + + AKE + + GG SL G G GP
Sbjct: 74 PQDLEASAGPAAGAAEEAKELLLPQDAGGPTSL--------GGGAGGPLLAERNRRTLAF 125
Query: 287 -GGSGAGTCNSSS 298
GG G G N+ S
Sbjct: 126 RGGGGGGLGNNGS 138
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 35.0 bits (79), Expect = 0.098
Identities = 47/184 (25%), Positives = 60/184 (32%), Gaps = 41/184 (22%)
Query: 154 PSPSFGQSPSPTFIPRSA---QP-ITFTTASFAATKFGSTKMKKGGGAASGGGVASSGAG 209
PS + + P P SA QP F A +T + A GGG + G G
Sbjct: 722 PSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGG 781
Query: 210 GQQPPQQPRMARSPTNSLLKHKSLS---------------------LSMHSLNFITANPA 248
G P QP S S K +LS LS N I + A
Sbjct: 782 GGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGA 841
Query: 249 P--------------QSQLSPNAKEFVYNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTC 294
P + +LS N + G S +F G G PGP G SG +
Sbjct: 842 PNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPG--GTAPGAPGPGGPSGTSSS 899
Query: 295 NSSS 298
S +
Sbjct: 900 GSKA 903
>gi|126090909 engrailed homeobox 1 [Homo sapiens]
Length = 392
Score = 34.3 bits (77), Expect = 0.17
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 9/81 (11%)
Query: 135 PDAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKG 194
PDA P GSQ ++ S ++ +P +A A+ AA K T
Sbjct: 173 PDANCGPPDGSQPAAAGAGAS----KAGNPAAAAAAAAAAVAAAAAAAAAKPSDT----- 223
Query: 195 GGAASGGGVASSGAGGQQPPQ 215
GG SGGG S GA G + P+
Sbjct: 224 GGGGSGGGAGSPGAQGTKYPE 244
>gi|196114945 myocyte enhancer factor 2C isoform 2 [Homo sapiens]
Length = 463
Score = 34.3 bits (77), Expect = 0.17
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 15/146 (10%)
Query: 124 ELDKEIKSSFNP-------DAQVFVPIGSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITF 176
E D IKS P + V +P+ S +S + ++P S G +P +P + +
Sbjct: 121 EFDNMIKSHKIPAVPPPNFEMPVSIPVSSHNSLVYSNPVSSLG---NPNLLPLAHPSLQR 177
Query: 177 TTASFAAT----KFGSTKMKKGGGAASGGGVASSGAGGQQPPQQPRMARSPTNSLLKHKS 232
+ S T G+T GG SG G S+G G P P + SP N ++
Sbjct: 178 NSMSPGVTHRPPSAGNTGGLMGGDLTSGAGT-SAGNGYGNPRNSPGLLVSPGNLNKNMQA 236
Query: 233 LSLSMHSLNFITANPAPQSQLSPNAK 258
S +L P + + P +K
Sbjct: 237 KSPPPMNLGMNNRKPDLRVLIPPGSK 262
>gi|22547204 hairless protein isoform a [Homo sapiens]
Length = 1189
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/147 (24%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 157 SFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGG----GVASSGAGGQQ 212
+ G P PR P T + + TK GGG G G+ +G +
Sbjct: 301 NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTK---GGGLGPCGKCQEGLEGGASGASE 357
Query: 213 PPQQPRMARSPTNSLLKH----KSLSLSMHSLNFITANPAPQSQLSPNAKEFVYNGGGSP 268
P ++ A P H K L+ HS F P+ + P A+ GSP
Sbjct: 358 PSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSP 417
Query: 269 SLFFDAADGQGSGTPGPFGGS---GAG 292
+ P PF G+ GAG
Sbjct: 418 EVQGAMGSPAPKRPPDPFPGTAEQGAG 444
>gi|22547207 hairless protein isoform b [Homo sapiens]
Length = 1134
Score = 34.3 bits (77), Expect = 0.17
Identities = 36/147 (24%), Positives = 50/147 (34%), Gaps = 14/147 (9%)
Query: 157 SFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGG----GVASSGAGGQQ 212
+ G P PR P T + + TK GGG G G+ +G +
Sbjct: 301 NLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTK---GGGLGPCGKCQEGLEGGASGASE 357
Query: 213 PPQQPRMARSPTNSLLKH----KSLSLSMHSLNFITANPAPQSQLSPNAKEFVYNGGGSP 268
P ++ A P H K L+ HS F P+ + P A+ GSP
Sbjct: 358 PSEEVNKASGPRACPPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVARLRALKRAGSP 417
Query: 269 SLFFDAADGQGSGTPGPFGGS---GAG 292
+ P PF G+ GAG
Sbjct: 418 EVQGAMGSPAPKRPPDPFPGTAEQGAG 444
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 34.3 bits (77), Expect = 0.17
Identities = 27/98 (27%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Query: 134 NPDAQVFVPIGSQDSSL--SNSPSPSFGQ-SPSPTFIPRSAQPIT-FTTASFAATKFGST 189
+P A + + SSL ++SP+ S G +P + R P++ + F++ K
Sbjct: 932 SPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKP 991
Query: 190 KMKKGGGAASGGGVASSGAGGQQPPQQPRMARSPTNSL 227
G S G+ S A PP PR + SP++SL
Sbjct: 992 GAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSL 1029
>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
Length = 508
Score = 33.9 bits (76), Expect = 0.22
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 16/153 (10%)
Query: 148 SSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSG 207
SSLS+S S SFG+ P S+ + + + FG + + GG++S A++
Sbjct: 35 SSLSDSSS-SFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAA 93
Query: 208 AGGQQPPQQPRMA--RSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEF-VYNG 264
A + SP +S + SL+ S A A + SP A ++ V+
Sbjct: 94 AAAAAALVSDSFSCGGSPGSS-----AFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQA 148
Query: 265 GGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSS 297
G + G G G G GGS A + + S
Sbjct: 149 PG-------VSGGSGGGGGGGGGGSSAHSQDGS 174
>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
Length = 490
Score = 33.9 bits (76), Expect = 0.22
Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 16/153 (10%)
Query: 148 SSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGGAASGGGVASSG 207
SSLS+S S SFG+ P S+ + + + FG + + GG++S A++
Sbjct: 17 SSLSDSSS-SFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGASRNGGSSSAAAAAAAA 75
Query: 208 AGGQQPPQQPRMA--RSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEF-VYNG 264
A + SP +S + SL+ S A A + SP A ++ V+
Sbjct: 76 AAAAAALVSDSFSCGGSPGSS-----AFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQA 130
Query: 265 GGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSS 297
G + G G G G GGS A + + S
Sbjct: 131 PG-------VSGGSGGGGGGGGGGSSAHSQDGS 156
>gi|89276766 trophinin isoform 5 [Homo sapiens]
Length = 1431
Score = 33.9 bits (76), Expect = 0.22
Identities = 26/70 (37%), Positives = 35/70 (50%), Gaps = 5/70 (7%)
Query: 145 SQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKFGSTKMKKGGG-----AAS 199
S +S SN+ S SFG + S + SA I+F A +T F S GG A+
Sbjct: 764 STSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASF 823
Query: 200 GGGVASSGAG 209
GGV+SS +G
Sbjct: 824 SGGVSSSFSG 833
Score = 33.1 bits (74), Expect = 0.37
Identities = 51/194 (26%), Positives = 74/194 (38%), Gaps = 27/194 (13%)
Query: 145 SQDSSLSNSPSPSFGQSPSPTFIPRSAQPITF-----TTASFA---ATKFG---STKMKK 193
S SS S++ S SFG + S + S I+F T+ASF+ ++ F ST
Sbjct: 782 STSSSFSSAASISFGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSFSGPLSTSATF 841
Query: 194 GGGAASG-GGVASSGAG-GQQPPQQPRMARSPTNSLLKHKSLSLSMHSLNFIT------A 245
GGA+SG GG S+ AG +PT S + +LS S ++
Sbjct: 842 SGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGGILSTSVCFGG 901
Query: 246 NPAPQSQLSPNAKEFVYNGGG-------SPSLFFDAADGQGSGTPGPFGGS-GAGTCNSS 297
+P+ + GG +L + G S T FGG+ C
Sbjct: 902 SPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDG 961
Query: 298 SFDMAQVFGGGANS 311
S FGG N+
Sbjct: 962 SPSTGAGFGGALNT 975
Score = 28.9 bits (63), Expect = 7.0
Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 3/97 (3%)
Query: 115 DDSEGCGAPELDKEIKSSFNPDAQVFVPIG---SQDSSLSNSPSPSFGQSPSPTFIPRSA 171
DD++ + E ++ N DA V S + S+ S SF +PS +
Sbjct: 695 DDAQAWSRFSFEIEARAQENADASTNVNFSRGASTRAGFSDGASISFNGAPSSSGGFSGG 754
Query: 172 QPITFTTASFAATKFGSTKMKKGGGAASGGGVASSGA 208
ITF A + F +T GG S SS A
Sbjct: 755 PGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAA 791
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 33.9 bits (76), Expect = 0.22
Identities = 32/108 (29%), Positives = 43/108 (39%), Gaps = 19/108 (17%)
Query: 204 ASSGAGGQQPPQQPRMARSPTNSLLKHKSLSLSMHSLNFITANPAPQSQLSPNAKEFVYN 263
ASSG PP + P +S +L+ A A + + A V+
Sbjct: 428 ASSGYESSTPPGLVSPSAEPQSS-----------SNLSPAAAAAAAAAAAAAAAVSAVHR 476
Query: 264 GGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFDMAQVFGGGANS 311
GGGS S G GSG+ G GG+G G SS GGG+ +
Sbjct: 477 GGGSGSGGAGGGSGGGSGSGGGGGGAGGGGGGSS--------GGGSGT 516
Score = 31.2 bits (69), Expect = 1.4
Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 9/73 (12%)
Query: 146 QDSSLSNSPSPSFGQSPSPTFIPRSAQP---------ITFTTASFAATKFGSTKMKKGGG 196
Q S S + S + S P + SA+P A+ AA + + +GGG
Sbjct: 420 QGSESSPAASSGYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGG 479
Query: 197 AASGGGVASSGAG 209
+ SGG SG G
Sbjct: 480 SGSGGAGGGSGGG 492
Score = 30.4 bits (67), Expect = 2.4
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 3/70 (4%)
Query: 144 GSQDSSLSNSPSPSFGQSPSPTFIPRSAQPITFTTASFAATKF---GSTKMKKGGGAASG 200
G + S+ SPS S P +A A+ AA G G G SG
Sbjct: 431 GYESSTPPGLVSPSAEPQSSSNLSPAAAAAAAAAAAAAAAVSAVHRGGGSGSGGAGGGSG 490
Query: 201 GGVASSGAGG 210
GG S G GG
Sbjct: 491 GGSGSGGGGG 500
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 33.9 bits (76), Expect = 0.22
Identities = 19/50 (38%), Positives = 23/50 (46%), Gaps = 5/50 (10%)
Query: 262 YNGGGSPSLFFDAADGQGSGTPGPFGGSGAGTCNSSSFDMAQVFGGGANS 311
Y+GGG S G G G+ G GG G G C S + GGG +S
Sbjct: 53 YSGGGGYS-----GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSS 97
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 33.9 bits (76), Expect = 0.22
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 7/81 (8%)
Query: 220 ARSPTNSLLKHKSLSLSMHS---LNFITANPAPQSQLSPNAKEFVYNGGGSPSLFFDAAD 276
A + + L HKSLS S F + P L+P +E + SP F+ AD
Sbjct: 10 AAAGEDDLFLHKSLSASTSKRLEAAFRSTPPGMDLSLAPPPRERPASSSSSPLGCFEPAD 69
Query: 277 GQGSG----TPGPFGGSGAGT 293
+G+G PG GG AG+
Sbjct: 70 PEGAGLLLPPPGGGGGGSAGS 90
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,964,793
Number of Sequences: 37866
Number of extensions: 842821
Number of successful extensions: 5364
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 4556
Number of HSP's gapped (non-prelim): 867
length of query: 344
length of database: 18,247,518
effective HSP length: 103
effective length of query: 241
effective length of database: 14,347,320
effective search space: 3457704120
effective search space used: 3457704120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.