Guide to the Human Genome
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Search of human proteins with 7705330

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705330 COP9 complex subunit 7a [Homo sapiens]
         (275 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705330 COP9 complex subunit 7a [Homo sapiens]                     530   e-151
gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7...   301   3e-82
gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Hom...    39   0.004
gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Hom...    39   0.004
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  38   0.008
gi|32698688 citron [Homo sapiens]                                      35   0.071
gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo...    33   0.21 
gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo...    33   0.21 
gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]                       33   0.27 
gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]                         33   0.27 
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                32   0.46 
gi|109134347 NY-REN-58 antigen [Homo sapiens]                          32   0.46 
gi|109134355 NY-REN-58 antigen [Homo sapiens]                          32   0.46 
gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]       32   0.46 
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    32   0.60 
gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]                 32   0.60 
gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]              32   0.79 
gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]             32   0.79 
gi|42794779 myosin 18A isoform b [Homo sapiens]                        32   0.79 
gi|28416946 myosin 18A isoform a [Homo sapiens]                        32   0.79 
gi|39930343 transmembrane and coiled-coil domain family 1 isofor...    32   0.79 
gi|190014612 transmembrane and coiled-coil domain family 1 isofo...    32   0.79 
gi|190014610 transmembrane and coiled-coil domain family 1 isofo...    32   0.79 
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom...    31   1.0  
gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1 [...    31   1.3  
gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2 [...    31   1.3  
gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3 [...    31   1.3  
gi|146262005 CTAGE family, member 6 [Homo sapiens]                     31   1.3  
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    31   1.3  
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H...    30   1.8  

>gi|7705330 COP9 complex subunit 7a [Homo sapiens]
          Length = 275

 Score =  530 bits (1364), Expect = e-151
 Identities = 275/275 (100%), Positives = 275/275 (100%)

Query: 1   MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF 60
           MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF
Sbjct: 1   MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF 60

Query: 61  ASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEAL 120
           ASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEAL
Sbjct: 61  ASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEAL 120

Query: 121 ALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVG 180
           ALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVG
Sbjct: 121 ALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVG 180

Query: 181 CEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLT 240
           CEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLT
Sbjct: 181 CEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLT 240

Query: 241 ELREPAPGTNQRQPSKKASKGKGLRGSAKIWSKSN 275
           ELREPAPGTNQRQPSKKASKGKGLRGSAKIWSKSN
Sbjct: 241 ELREPAPGTNQRQPSKKASKGKGLRGSAKIWSKSN 275


>gi|12232385 COP9 constitutive photomorphogenic homolog subunit 7B
           [Homo sapiens]
          Length = 264

 Score =  301 bits (772), Expect = 3e-82
 Identities = 154/267 (57%), Positives = 204/267 (76%), Gaps = 5/267 (1%)

Query: 1   MSAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDF 60
           M+ E K +    EQF+LLAK   G+AL  LI QVLEAPGVYVFGELL++ NV+ELAE   
Sbjct: 1   MAGEQKPSSNLLEQFILLAKGTSGSALTALISQVLEAPGVYVFGELLELANVQELAEGAN 60

Query: 61  ASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEAL 120
           A+  +LL +FAYGTY DY+A   +LP L+ AQ+NKL+HL++V+LA+++KCIPY+VLL+ L
Sbjct: 61  AAYLQLLNLFAYGTYPDYIANKESLPELSTAQQNKLKHLTIVSLASRMKCIPYSVLLKDL 120

Query: 121 ALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVG 180
            +RN+R+LEDL+IEAVY D+++G LDQRNQ LEVD+ IGRDI+++D++ I +TL EWC G
Sbjct: 121 EMRNLRELEDLIIEAVYTDIIQGKLDQRNQLLEVDFCIGRDIRKKDINNIVKTLHEWCDG 180

Query: 181 CEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLT 240
           CE VL GIE+QV RANQ+KE     +QQ+E+EV N+KKT+K T    A++++Q+ EQ L 
Sbjct: 181 CEAVLLGIEQQVLRANQYKENHNRTQQQVEAEVTNIKKTLKAT----ASSSAQEMEQQLA 236

Query: 241 ELREPAPGTNQRQPSKKASKGKGLRGS 267
           E RE  P   QRQP+KK SK KGL  S
Sbjct: 237 E-RECPPHAEQRQPTKKMSKVKGLVSS 262


>gi|157502195 proteasome 26S non-ATPase subunit 13 isoform 2 [Homo
           sapiens]
          Length = 378

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 9/162 (5%)

Query: 39  GVYVFGELLDMPNVRELAESDFASTFRLLTVFAYGTYADYLAEAR---NLPPLTEAQKNK 95
           GV+ FGELL  P +  L  +D       L  F  G    +          P L   +   
Sbjct: 211 GVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQL 270

Query: 96  LRHLSVVTLAAKVKCIPY---AVLLEALALR---NVRQLEDLVIEAVYADVLRGSLDQRN 149
           LR + ++ L       P     +  E +A      V ++E LV++A+   +++GS+D+ +
Sbjct: 271 LRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVD 330

Query: 150 QRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQ 191
           +R+ + +   R +  Q +  +   L+ WC   + +   +E Q
Sbjct: 331 KRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQ 372


>gi|157502193 proteasome 26S non-ATPase subunit 13 isoform 1 [Homo
           sapiens]
          Length = 376

 Score = 39.3 bits (90), Expect = 0.004
 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 9/162 (5%)

Query: 39  GVYVFGELLDMPNVRELAESDFASTFRLLTVFAYGTYADYLAEAR---NLPPLTEAQKNK 95
           GV+ FGELL  P +  L  +D       L  F  G    +          P L   +   
Sbjct: 209 GVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQL 268

Query: 96  LRHLSVVTLAAKVKCIPY---AVLLEALALR---NVRQLEDLVIEAVYADVLRGSLDQRN 149
           LR + ++ L       P     +  E +A      V ++E LV++A+   +++GS+D+ +
Sbjct: 269 LRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVD 328

Query: 150 QRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQ 191
           +R+ + +   R +  Q +  +   L+ WC   + +   +E Q
Sbjct: 329 KRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQ 370


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 38.1 bits (87), Expect = 0.008
 Identities = 40/150 (26%), Positives = 67/150 (44%), Gaps = 15/150 (10%)

Query: 115  VLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTL 174
            V + A  L  +R  EDLV+E + +  L   LD+ +Q LE    + R++  Q+  + + T 
Sbjct: 900  VTVHARTLTTLR--EDLVLEKLKSQQLSSELDKLSQELE-KVGLNRELLLQEDDSGSDTK 956

Query: 175  QEWCVG-----CEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAA 229
             +   G      +  L+  EE++       E++  L +Q+ESE+  LKK  +        
Sbjct: 957  YKILEGRNESALKTTLAMKEEKIVLLEAQMEEKASLNRQLESELQMLKKECE------TL 1010

Query: 230  ATSQDPEQHL-TELREPAPGTNQRQPSKKA 258
              +Q   QHL    + PA  T      K+A
Sbjct: 1011 RQNQGEGQHLQNSFKHPAGKTAASHQGKEA 1040


>gi|32698688 citron [Homo sapiens]
          Length = 2027

 Score = 35.0 bits (79), Expect = 0.071
 Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 22/129 (17%)

Query: 123 RNVRQLEDLVIEA----VYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWC 178
           RN++  E+++ E      Y +   G L+ +N++LE        I  QD S   R L+   
Sbjct: 800 RNMKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLE---KISHQDHSDKNRLLE--- 853

Query: 179 VGCEVVLSGIEEQVSRAN-QHKEQQLGLKQQIESEVANLKKTIKVTTA--AAAAATSQDP 235
                    +E ++   + +H+EQ+L LK+Q+     +L++     TA  AA AA     
Sbjct: 854 ---------LETRLREVSLEHEEQKLELKRQLTELQLSLQERESQLTALQAARAALESQL 904

Query: 236 EQHLTELRE 244
            Q  TEL E
Sbjct: 905 RQAKTELEE 913


>gi|32528293 ecto-NOX disulfide-thiol exchanger 2 isoform a [Homo
           sapiens]
          Length = 581

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 5/118 (4%)

Query: 139 DVLRGSLDQRNQRLEVDYSIGRDIQRQD---LSAIARTLQEWCVGCEVVLSGIEEQVSRA 195
           D LR  LD     +E+       + R+D        + LQ+   G +  L  ++E+  + 
Sbjct: 390 DSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKK 449

Query: 196 NQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQ 253
               E+    K Q+E  + NLK+  K + A+   A++QD E  L +    +P  ++R+
Sbjct: 450 EAELEKLKDDKLQVEKMLENLKE--KESCASRLCASNQDSEYPLEKTMNSSPIKSERE 505


>gi|32528291 ecto-NOX disulfide-thiol exchanger 2 isoform b [Homo
           sapiens]
          Length = 610

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 29/118 (24%), Positives = 53/118 (44%), Gaps = 5/118 (4%)

Query: 139 DVLRGSLDQRNQRLEVDYSIGRDIQRQD---LSAIARTLQEWCVGCEVVLSGIEEQVSRA 195
           D LR  LD     +E+       + R+D        + LQ+   G +  L  ++E+  + 
Sbjct: 419 DSLRWQLDAYRNEVELLKQEQGKVHREDDPNKEQQLKLLQQALQGMQQHLLKVQEEYKKK 478

Query: 196 NQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQ 253
               E+    K Q+E  + NLK+  K + A+   A++QD E  L +    +P  ++R+
Sbjct: 479 EAELEKLKDDKLQVEKMLENLKE--KESCASRLCASNQDSEYPLEKTMNSSPIKSERE 534


>gi|187607364 tuftelin 1 isoform 2 [Homo sapiens]
          Length = 365

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 11/102 (10%)

Query: 153 EVDYSIGRDIQR-----QDLSA----IARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQL 203
           EVD  I  D++      QDL A      R  Q  CV  EV LS  + +  ++N   +++ 
Sbjct: 135 EVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREE 194

Query: 204 GLKQQIESEVANLKKTI--KVTTAAAAAATSQDPEQHLTELR 243
              +Q E+EV  L++ +    T   A  A  ++ E  L ELR
Sbjct: 195 DRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELR 236


>gi|9910596 tuftelin 1 isoform 1 [Homo sapiens]
          Length = 390

 Score = 33.1 bits (74), Expect = 0.27
 Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 11/102 (10%)

Query: 153 EVDYSIGRDIQR-----QDLSA----IARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQL 203
           EVD  I  D++      QDL A      R  Q  CV  EV LS  + +  ++N   +++ 
Sbjct: 160 EVDTCINEDVESLRKTVQDLLAKLQEAKRQHQSDCVAFEVTLSRYQREAEQSNVALQREE 219

Query: 204 GLKQQIESEVANLKKTI--KVTTAAAAAATSQDPEQHLTELR 243
              +Q E+EV  L++ +    T   A  A  ++ E  L ELR
Sbjct: 220 DRVEQKEAEVGELQRRLLGMETEHQALLAKVREGEVALEELR 261


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 58/240 (24%), Positives = 94/240 (39%), Gaps = 26/240 (10%)

Query: 1    MSAEVKVTGQNQEQFLLLAKSAKGAALA------TLIHQVLEAPGVYVFGELLDMPNVRE 54
            +S E+    Q +++ LLLA+S K  AL+      T + + L      +    L+M   + 
Sbjct: 1038 LSEEIAALQQERDEGLLLAESEKQQALSLKESEKTALSEKLMGTRHSLATISLEMERQKR 1097

Query: 55   LAES---DFASTFRLLTVFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCI 111
             A+S      ST   LT        D  A+          +  +L+  +      +  C 
Sbjct: 1098 DAQSRQEQDRSTVNALT----SELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSC- 1152

Query: 112  PYAVLLEALALRN-VRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAI 170
                L EA  LR  +R LED        D LR  L +  ++L      GR++QRQ+   +
Sbjct: 1153 ----LREAEELRTQLRLLEDA------RDGLRRELLEAQRKLRESQE-GREVQRQEAGEL 1201

Query: 171  ARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAA 230
             R+L E     E +    EE  S   + + +++ LK   E +   L    +  TA    A
Sbjct: 1202 RRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEA 1261


>gi|109134347 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 42/151 (27%), Positives = 63/151 (41%), Gaps = 19/151 (12%)

Query: 95  KLRHLSVVTLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGS-LDQRNQRLE 153
           K R L     AAK +     V+L+   L    +L DL    V  DV R S  DQ  ++L 
Sbjct: 372 KDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLR 431

Query: 154 VDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEV 213
               +  +I R++L ++   LQ+  V            +  A + K +   LKQQI S  
Sbjct: 432 AS-QMAEEITRKELQSVRLKLQQQIV-----------TIENAEKEKNENSDLKQQISS-- 477

Query: 214 ANLKKTIKVTTAAAAAATSQDPEQHLTELRE 244
                 I+VT+ A +     +  Q L E+ E
Sbjct: 478 ----LQIQVTSLAQSENDLLNSNQMLKEMVE 504


>gi|109134355 NY-REN-58 antigen [Homo sapiens]
          Length = 701

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 42/151 (27%), Positives = 63/151 (41%), Gaps = 19/151 (12%)

Query: 95  KLRHLSVVTLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGS-LDQRNQRLE 153
           K R L     AAK +     V+L+   L    +L DL    V  DV R S  DQ  ++L 
Sbjct: 372 KDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLR 431

Query: 154 VDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEV 213
               +  +I R++L ++   LQ+  V            +  A + K +   LKQQI S  
Sbjct: 432 AS-QMAEEITRKELQSVRLKLQQQIV-----------TIENAEKEKNENSDLKQQISS-- 477

Query: 214 ANLKKTIKVTTAAAAAATSQDPEQHLTELRE 244
                 I+VT+ A +     +  Q L E+ E
Sbjct: 478 ----LQIQVTSLAQSENDLLNSNQMLKEMVE 504


>gi|21264320 NLR family, pyrin domain containing 6 [Homo sapiens]
          Length = 892

 Score = 32.3 bits (72), Expect = 0.46
 Identities = 41/168 (24%), Positives = 66/168 (39%), Gaps = 17/168 (10%)

Query: 85  LPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGS 144
           L  L++ Q  + RH  +  +    + IP+  L  A A+    QL          +V R +
Sbjct: 26  LEELSQEQLKRFRH-KLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKT 84

Query: 145 LDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLG 204
           L + + R      +   +Q        R LQ   +G   +LS  E +     +++E  L 
Sbjct: 85  LKRADAR-----DVAAQLQE-------RRLQRLGLGSGTLLSVSEYK----KKYREHVLQ 128

Query: 205 LKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQR 252
           L  +++   A   K  K  T    A  S  PE+ L    EP PG  +R
Sbjct: 129 LHARVKERNARSVKITKRFTKLLIAPESAAPEEALGPAEEPEPGRARR 176


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 18/126 (14%)

Query: 106  AKVKCIPYAVLLEALALRNVRQLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQ 165
            +K K +   VL    ++++VR+  + ++E V    L+  +DQ    L+ DY        Q
Sbjct: 3842 SKYKSLQQTVLSHEPSVKSVREKGEALLELVQDVTLKDKIDQ----LQSDY--------Q 3889

Query: 166  DLSAIARTLQEWCVGCEVVLSGIEEQ----VSRANQHKEQQLGLKQQIESEVANLKKTIK 221
            DL +I + + E   G E  L+ ++ +    + +   H   Q  LKQ + + +   K +  
Sbjct: 3890 DLCSIGKAMMEEIAGFEDRLNNLQMKGDTLIGQCADH--LQAKLKQNVHAHLQGTKDSYS 3947

Query: 222  VTTAAA 227
               + A
Sbjct: 3948 AICSTA 3953


>gi|22208850 Golgi coiled-coil protein 1 [Homo sapiens]
          Length = 775

 Score = 32.0 bits (71), Expect = 0.60
 Identities = 25/105 (23%), Positives = 43/105 (40%), Gaps = 1/105 (0%)

Query: 144 SLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQL 203
           ++ Q   R+E  Y   +   +QDL   +   +E     E  L G++EQ++        Q 
Sbjct: 174 TVTQEKSRMEASYLADKKKMKQDLEDASNKAEEERARLEGELKGLQEQIAETKARLITQQ 233

Query: 204 GLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELREPAPG 248
             + Q +S+ A + + ++           QD E  L E RE   G
Sbjct: 234 HDRAQEQSDHALMLRELQ-KLLQEERTQRQDLELRLEETREALAG 277


>gi|47519616 tropomyosin 2 (beta) isoform 2 [Homo sapiens]
          Length = 284

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 18/111 (16%)

Query: 140 VLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHK 199
           +L G L++  +R EV  S  R ++ +      RT+ +     + +++  EE  ++ ++++
Sbjct: 171 ILEGELERSEERAEVAESRARQLEEE-----LRTMDQ---ALKSLMASEEEYSTKEDKYE 222

Query: 200 EQQLGLKQQI----------ESEVANLKKTIKVTTAAAAAATSQDPEQHLT 240
           E+   L++++          E  VA L+KTI       A+A  ++ E H T
Sbjct: 223 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQT 273


>gi|224922812 tropomyosin 2 (beta) isoform 3 [Homo sapiens]
          Length = 231

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 26/111 (23%), Positives = 54/111 (48%), Gaps = 18/111 (16%)

Query: 140 VLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHK 199
           +L G L++  +R EV  S  R ++ +      RT+ +     + +++  EE  ++ ++++
Sbjct: 118 ILEGELERSEERAEVAESRARQLEEE-----LRTMDQ---ALKSLMASEEEYSTKEDKYE 169

Query: 200 EQQLGLKQQI----------ESEVANLKKTIKVTTAAAAAATSQDPEQHLT 240
           E+   L++++          E  VA L+KTI       A+A  ++ E H T
Sbjct: 170 EEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEETLASAKEENVEIHQT 220


>gi|42794779 myosin 18A isoform b [Homo sapiens]
          Length = 2039

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 36/152 (23%), Positives = 70/152 (46%), Gaps = 10/152 (6%)

Query: 79   LAEARNLPPLTEAQKNKLRHLS--VVTLAAKVKCIPYAVLLEALALRNVR-QLEDLVIEA 135
            LAEA +L    E +   +   +  VV+L A+++ I      +  +L  V+ QL DL  + 
Sbjct: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKV 1551

Query: 136  V----YADVLRGS---LDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGI 188
                   D   G+   L+Q   RLE++    R    +++ +    ++E    C+  L  +
Sbjct: 1552 KDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM 1611

Query: 189  EEQVSRANQHKEQQLGLKQQIESEVANLKKTI 220
            E Q+    + K++ L  K+++E ++A L   +
Sbjct: 1612 EVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643


>gi|28416946 myosin 18A isoform a [Homo sapiens]
          Length = 2054

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 36/152 (23%), Positives = 70/152 (46%), Gaps = 10/152 (6%)

Query: 79   LAEARNLPPLTEAQKNKLRHLS--VVTLAAKVKCIPYAVLLEALALRNVR-QLEDLVIEA 135
            LAEA +L    E +   +   +  VV+L A+++ I      +  +L  V+ QL DL  + 
Sbjct: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKV 1551

Query: 136  V----YADVLRGS---LDQRNQRLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGI 188
                   D   G+   L+Q   RLE++    R    +++ +    ++E    C+  L  +
Sbjct: 1552 KDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM 1611

Query: 189  EEQVSRANQHKEQQLGLKQQIESEVANLKKTI 220
            E Q+    + K++ L  K+++E ++A L   +
Sbjct: 1612 EVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643


>gi|39930343 transmembrane and coiled-coil domain family 1 isoform b
           [Homo sapiens]
          Length = 329

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 5/62 (8%)

Query: 151 RLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQ-HKEQQLGLKQQI 209
           RLE  +   ++  ++D S I +TLQE    CE     +EEQ++   + H+ + L LKQ++
Sbjct: 151 RLEESFETLKEHYQRDYSLIMQTLQEERYRCE----RLEEQLNDLTELHQNEILNLKQEL 206

Query: 210 ES 211
            S
Sbjct: 207 AS 208


>gi|190014612 transmembrane and coiled-coil domain family 1 isoform
           c [Homo sapiens]
          Length = 539

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 5/62 (8%)

Query: 151 RLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQ-HKEQQLGLKQQI 209
           RLE  +   ++  ++D S I +TLQE    CE     +EEQ++   + H+ + L LKQ++
Sbjct: 361 RLEESFETLKEHYQRDYSLIMQTLQEERYRCE----RLEEQLNDLTELHQNEILNLKQEL 416

Query: 210 ES 211
            S
Sbjct: 417 AS 418


>gi|190014610 transmembrane and coiled-coil domain family 1 isoform
           a [Homo sapiens]
          Length = 653

 Score = 31.6 bits (70), Expect = 0.79
 Identities = 21/62 (33%), Positives = 35/62 (56%), Gaps = 5/62 (8%)

Query: 151 RLEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQ-HKEQQLGLKQQI 209
           RLE  +   ++  ++D S I +TLQE    CE     +EEQ++   + H+ + L LKQ++
Sbjct: 475 RLEESFETLKEHYQRDYSLIMQTLQEERYRCE----RLEEQLNDLTELHQNEILNLKQEL 530

Query: 210 ES 211
            S
Sbjct: 531 AS 532


>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
           sapiens]
          Length = 1631

 Score = 31.2 bits (69), Expect = 1.0
 Identities = 43/173 (24%), Positives = 72/173 (41%), Gaps = 26/173 (15%)

Query: 73  GTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCIPYAVLLEALALRNV--RQLED 130
           G   D LA  +N   L E  +  L        A   + +  A + +A   RN   R+ +D
Sbjct: 221 GVVEDTLAALQNPSALLENLREPLA-------AVYQEMLAQAKMEKAANARNHDDRESQD 273

Query: 131 LVIEAVYADVLRGSLDQRNQR--LEVDYSIGRDIQRQDLSAIARTLQEWCVGCEVVLSGI 188
           +    +    ++G+++  N    LEV   +   ++RQ   A+ + LQ+  +    V    
Sbjct: 274 IYDHYLTQAEIQGNINHVNVHGALEV---VDDALERQSPEALLKALQDPALALRGVRRDF 330

Query: 189 E----EQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQ 237
                EQ++   + K Q+LGL + +E E        +V    AAA T  D EQ
Sbjct: 331 ADWYLEQLNSDREQKAQELGLVELLEKE--------EVQAGVAAANTKGDQEQ 375


>gi|157738615 coiled-coil alpha-helical rod protein 1 isoform 1
           [Homo sapiens]
          Length = 871

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 64/289 (22%), Positives = 111/289 (38%), Gaps = 48/289 (16%)

Query: 2   SAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDFA 61
           S + KVT Q+QEQ  +L +S +  A    + + + A G+ +  EL      R   +   A
Sbjct: 457 SLQEKVTSQSQEQ-AILQRSLQDKAAEVEVER-MGAKGLQL--ELSRAQEARRRWQQQTA 512

Query: 62  ST---FRLLT-------VFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCI 111
           S     RL+        ++   T A     A  LP L       +R +  +         
Sbjct: 513 SAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIR-------- 564

Query: 112 PYAVLLEALALRNVRQ--------LEDLVIEAVYADVLRGSLD---QRNQRLEVDYSIGR 160
              ++   LAL  +RQ        + D+ +E       R  LD   Q + RL +   +GR
Sbjct: 565 --GLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARL-IQQEVGR 621

Query: 161 -----DIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVAN 215
                + +RQ LS +A+ L++     +  L+ +  Q+  A Q        +Q+   E A+
Sbjct: 622 AREQGEAERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQG-------QQESTEEAAS 674

Query: 216 LKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQPSKKASKGKGL 264
           L++ +         A  +   +  T LRE    T +R    +    K +
Sbjct: 675 LRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAV 723


>gi|157738613 coiled-coil alpha-helical rod protein 1 isoform 2
           [Homo sapiens]
          Length = 835

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 64/289 (22%), Positives = 111/289 (38%), Gaps = 48/289 (16%)

Query: 2   SAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDFA 61
           S + KVT Q+QEQ  +L +S +  A    + + + A G+ +  EL      R   +   A
Sbjct: 421 SLQEKVTSQSQEQ-AILQRSLQDKAAEVEVER-MGAKGLQL--ELSRAQEARRRWQQQTA 476

Query: 62  ST---FRLLT-------VFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCI 111
           S     RL+        ++   T A     A  LP L       +R +  +         
Sbjct: 477 SAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIR-------- 528

Query: 112 PYAVLLEALALRNVRQ--------LEDLVIEAVYADVLRGSLD---QRNQRLEVDYSIGR 160
              ++   LAL  +RQ        + D+ +E       R  LD   Q + RL +   +GR
Sbjct: 529 --GLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARL-IQQEVGR 585

Query: 161 -----DIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVAN 215
                + +RQ LS +A+ L++     +  L+ +  Q+  A Q        +Q+   E A+
Sbjct: 586 AREQGEAERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQG-------QQESTEEAAS 638

Query: 216 LKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQPSKKASKGKGL 264
           L++ +         A  +   +  T LRE    T +R    +    K +
Sbjct: 639 LRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAV 687


>gi|157738611 coiled-coil alpha-helical rod protein 1 isoform 3
           [Homo sapiens]
          Length = 782

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 64/289 (22%), Positives = 111/289 (38%), Gaps = 48/289 (16%)

Query: 2   SAEVKVTGQNQEQFLLLAKSAKGAALATLIHQVLEAPGVYVFGELLDMPNVRELAESDFA 61
           S + KVT Q+QEQ  +L +S +  A    + + + A G+ +  EL      R   +   A
Sbjct: 368 SLQEKVTSQSQEQ-AILQRSLQDKAAEVEVER-MGAKGLQL--ELSRAQEARRRWQQQTA 423

Query: 62  ST---FRLLT-------VFAYGTYADYLAEARNLPPLTEAQKNKLRHLSVVTLAAKVKCI 111
           S     RL+        ++   T A     A  LP L       +R +  +         
Sbjct: 424 SAEEQLRLVVNAVSSSQIWLETTMAKVEGAAAQLPSLNNRLSYAVRKVHTIR-------- 475

Query: 112 PYAVLLEALALRNVRQ--------LEDLVIEAVYADVLRGSLD---QRNQRLEVDYSIGR 160
              ++   LAL  +RQ        + D+ +E       R  LD   Q + RL +   +GR
Sbjct: 476 --GLIARKLALAQLRQESCPLPPPVTDVSLELQQLREERNRLDAELQLSARL-IQQEVGR 532

Query: 161 -----DIQRQDLSAIARTLQEWCVGCEVVLSGIEEQVSRANQHKEQQLGLKQQIESEVAN 215
                + +RQ LS +A+ L++     +  L+ +  Q+  A Q        +Q+   E A+
Sbjct: 533 AREQGEAERQQLSKVAQQLEQELQQTQESLASLGLQLEVARQG-------QQESTEEAAS 585

Query: 216 LKKTIKVTTAAAAAATSQDPEQHLTELREPAPGTNQRQPSKKASKGKGL 264
           L++ +         A  +   +  T LRE    T +R    +    K +
Sbjct: 586 LRQELTQQQELYGQALQEKVAEVETRLREQLSDTERRLNEARREHAKAV 634


>gi|146262005 CTAGE family, member 6 [Homo sapiens]
          Length = 777

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 10/90 (11%)

Query: 127 QLEDLVIEAVYADVLRGSLDQRNQRLEVDYSIGRDIQRQDLSAIARTL---QEWCVGCEV 183
           Q E L  E +Y        +  NQ+L+    I  +  ++D   + R L   + + +  E 
Sbjct: 362 QQESLQSENIY-------FESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEE 414

Query: 184 VLSGIEEQVSRANQHKEQQLGLKQQIESEV 213
            LS +EE++SRA +  E    L + +E E+
Sbjct: 415 KLSKVEEKLSRATEQLETYRKLAKDLEEEL 444


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding
           domain 1 [Homo sapiens]
          Length = 1412

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)

Query: 184 VLSGIEEQVSRANQHKEQQLGLKQQIESEVANLKKTIKVTTAAAAAATSQDPEQHLTELR 243
           V   +EE+ +R  + +E+    K+ +ES +A+ K+  K    +      QD E HLT+ +
Sbjct: 737 VKEALEEEQTRVQELEERLARQKEVLESSIAHEKRKAKEALESEKRKV-QDLENHLTQQK 795

Query: 244 E 244
           E
Sbjct: 796 E 796


>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
            sapiens]
          Length = 4515

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 20/89 (22%), Positives = 43/89 (48%), Gaps = 10/89 (11%)

Query: 165  QDLSAIARTLQEWCVGCE---------VVLSGIEEQVSRANQHKEQQLGLKQQIESEVAN 215
            Q+L+  + TL+EW + C+            S I  Q+    +   Q + + ++I S++ N
Sbjct: 1199 QNLTLFSYTLEEW-MNCQRNWLYLEPVFHSSEIRRQLPAETELFSQVISMWKKIMSKIQN 1257

Query: 216  LKKTIKVTTAAAAAATSQDPEQHLTELRE 244
             +  +++TT+A      Q+   HL  +++
Sbjct: 1258 KQNALQITTSAGVLEILQNCNIHLEHIKK 1286


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.129    0.351 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,876,799
Number of Sequences: 37866
Number of extensions: 338638
Number of successful extensions: 2002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 1917
Number of HSP's gapped (non-prelim): 134
length of query: 275
length of database: 18,247,518
effective HSP length: 101
effective length of query: 174
effective length of database: 14,423,052
effective search space: 2509611048
effective search space used: 2509611048
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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