Search of human proteins with 13994353

Search of human proteins with 13994353

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13994353 potassium channel tetramerisation domain containing
10 [Homo sapiens]
         (313 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13994353 potassium channel tetramerisation domain containing ...   628   e-180
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...   441   e-124
gi|30578412 potassium channel tetramerisation domain containing ...   431   e-121
gi|71143104 potassium channel tetramerisation domain containing ...    84   2e-16
gi|23308551 potassium channel tetramerisation domain containing ...    81   1e-15
gi|146198864 potassium channel tetramerisation domain containing...    76   4e-14
gi|189571693 potassium channel tetramerisation domain containing...    69   7e-12
gi|189571691 potassium channel tetramerisation domain containing...    69   7e-12
gi|38198663 potassium channel tetramerisation domain containing ...    64   2e-10
gi|142356950 potassium channel tetramerisation domain containing...    62   5e-10
gi|169234778 potassium channel tetramerisation domain containing...    62   7e-10
gi|45387953 potassium channel tetramerization domain containing ...    61   1e-09
gi|194018443 potassium channel tetramerisation domain containing...    59   4e-09
gi|194018441 potassium channel tetramerisation domain containing...    59   4e-09
gi|194018439 potassium channel tetramerisation domain containing...    59   4e-09
gi|9506651 potassium channel tetramerisation domain containing 5...    58   9e-09
gi|53829365 potassium channel tetramerisation domain containing ...    58   9e-09
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  58   1e-08
gi|218505694 potassium channel tetramerisation domain containing...    57   2e-08
gi|209969708 potassium channel tetramerisation domain containing...    57   2e-08
gi|40217617 potassium channel tetramerisation domain containing ...    57   2e-08
gi|55926200 potassium channel tetramerisation domain containing ...    55   6e-08
gi|39753959 potassium channel tetramerisation domain containing ...    55   6e-08
gi|19923973 potassium channel tetramerisation domain containing ...    54   2e-07
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    52   9e-07
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    52   9e-07
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...    52   9e-07
gi|46255026 potassium channel tetramerisation domain containing ...    52   9e-07
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       47   3e-05
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       47   3e-05

>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score =  628 bits (1620), Expect = e-180
 Identities = 313/313 (100%), Positives = 313/313 (100%)

Query: 1   MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM 60
           MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM
Sbjct: 1   MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAM 60

Query: 61  FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL 120
           FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL
Sbjct: 61  FSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL 120

Query: 121 VEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDD 180
           VEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDD
Sbjct: 121 VEECQAALQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDD 180

Query: 181 NMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQT 240
           NMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQT
Sbjct: 181 NMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQT 240

Query: 241 KVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRI 300
           KVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRI
Sbjct: 241 KVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRI 300

Query: 301 HIKRPDDRAHLHQ 313
           HIKRPDDRAHLHQ
Sbjct: 301 HIKRPDDRAHLHQ 313


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score =  441 bits (1135), Expect = e-124
 Identities = 222/314 (70%), Positives = 262/314 (83%), Gaps = 7/314 (2%)

Query: 4   MSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSG 63
           MSG++ +  A   A  + + FKG    +KYV+LNVGG+LYYTT++ LT+ DTMLKAMFSG
Sbjct: 1   MSGDTCLCPA-SGAKPKLSGFKGGGLGNKYVQLNVGGSLYYTTVRALTRHDTMLKAMFSG 59

Query: 64  RMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEE 123
           RMEVLTD EGWILIDRCGKHFGTILNYLRD  + LP++R+EI+EL+AEAKYYL+QGLV  
Sbjct: 60  RMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNM 119

Query: 124 CQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNM 182
           CQ+ALQ+K D+Y+P C +P+ITS KEE++LI +S KP VKLLYNRSNNKYSYTSNSDD++
Sbjct: 120 CQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNNKYSYTSNSDDHL 179

Query: 183 LKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKV 242
           LKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRK+AEVCCTSIVYATEKKQTKV
Sbjct: 180 LKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTSIVYATEKKQTKV 239

Query: 243 EFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRIHI 302
           EFPEARIYEETLN+LLYE    R PDN+LLEAT  +  ++   +++E  E  +RVRRIH+
Sbjct: 240 EFPEARIYEETLNVLLYETP--RVPDNSLLEATSRSRSQASPSEDEETFELRDRVRRIHV 297

Query: 303 KR---PDDRAHLHQ 313
           KR    DDR   HQ
Sbjct: 298 KRYSTYDDRQLGHQ 311


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score =  431 bits (1109), Expect = e-121
 Identities = 213/293 (72%), Positives = 252/293 (86%), Gaps = 6/293 (2%)

Query: 25  KGTSPSSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHF 84
           K  +P+SKYVKLNVGG+L+YTT++TLT QDTMLKAMFSGR+EVLTD+ GW+LIDR G+HF
Sbjct: 34  KPLTPNSKYVKLNVGGSLHYTTLRTLTGQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHF 93

Query: 85  GTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNK-DTYEPFCKVPVI 143
           GTILNYLRDG+VPLPES RE+ ELL EA+YYLVQGL+E+CQ ALQ K +T  P C +P++
Sbjct: 94  GTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMV 153

Query: 144 TSSKEEQKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLFI 203
           TS +EEQ+L+A+++KP VKLL+NRSNNKYSYTS SDDN+LKNIELFDKL+LRF+GR+LF+
Sbjct: 154 TSPREEQQLLASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFL 213

Query: 204 KDVIGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIYEETLNILLYEAQD 263
           KDV+GDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARI+EETLNIL+YE   
Sbjct: 214 KDVLGDEICCWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETP- 272

Query: 264 GRGPDNALLEATGGAAGRSHHLDEDEERERIERVRRIHIKR---PDDRAHLHQ 313
            RGPD ALLEATGGAAG       ++E  R  RVRRIH++R    D+R H  Q
Sbjct: 273 -RGPDPALLEATGGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQ 324


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 65/172 (37%), Positives = 89/172 (51%), Gaps = 15/172 (8%)

Query: 34  VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92
           + LNVGG LY T++ TLT   D+ML AMFSG+M    DS+G   IDR GK F  ILN+LR
Sbjct: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64

Query: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKL 152
              + LPE  +E+  L  EA +Y VQ L+E    ALQ K+          ++ +++   L
Sbjct: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIE----ALQEKEV--------ELSKAEKNAML 112

Query: 153 IATSNK--PAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLF 202
             T N+    V      +   YS +S+S +    NI     L L+  G  LF
Sbjct: 113 NITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLF 164


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 80.9 bits (198), Expect = 1e-15
 Identities = 44/93 (47%), Positives = 59/93 (63%), Gaps = 4/93 (4%)

Query: 34  VKLNVGGALYYTTMQTLT-KQDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92
           V LN+GGA + T + TL   +DTML AMFSGR  + TDSEG   IDR G HFG +LN+LR
Sbjct: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112

Query: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQ 125
            G +P    R  +  +  EA+YY +  L+E+ +
Sbjct: 113 SGDLP---PRERVRAVYKEAQYYAIGPLLEQLE 142


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 75.9 bits (185), Expect = 4e-14
 Identities = 43/103 (41%), Positives = 65/103 (63%), Gaps = 1/103 (0%)

Query: 25  KGTSPSSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDSEGWILIDRCGKH 83
           +G +  S  + LNVGG LY T  QTLTK  DT L+ + +G++    D++G   IDR G  
Sbjct: 26  QGKNCKSTLMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLL 85

Query: 84  FGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQA 126
           F  +LN+LR+G + LPE  RE + L  EA+++ ++GL EE ++
Sbjct: 86  FRHVLNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKS 128


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 46/129 (35%), Positives = 64/129 (49%), Gaps = 5/129 (3%)

Query: 34  VKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92
           V LNVGG LY T++ TLT+  D+ML AMF G      D +G   IDR G  F  +LN+LR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKL 152
              + LP   +E + L  EA +Y ++ L++     L +     P      +      +KL
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQ----CLNDPKPLYPMDTFEEVVELSSTRKL 129

Query: 153 IATSNKPAV 161
              SN  AV
Sbjct: 130 SKYSNPVAV 138


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 46/129 (35%), Positives = 64/129 (49%), Gaps = 5/129 (3%)

Query: 34  VKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92
           V LNVGG LY T++ TLT+  D+ML AMF G      D +G   IDR G  F  +LN+LR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKL 152
              + LP   +E + L  EA +Y ++ L++     L +     P      +      +KL
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQ----CLNDPKPLYPMDTFEEVVELSSTRKL 129

Query: 153 IATSNKPAV 161
              SN  AV
Sbjct: 130 SKYSNPVAV 138


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 50/127 (39%), Positives = 65/127 (51%), Gaps = 11/127 (8%)

Query: 7   ESVVSSAVP-AAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSG- 63
           E V SS+ P A+A         SP  + V+LNVGG +Y T   TL    D+ L +MFS  
Sbjct: 18  EMVSSSSSPGASAAAAPGPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPS 77

Query: 64  --------RMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYY 115
                   R E+  DS     IDR G  F  +L+YLRD  + LPE   E E LL EA+Y+
Sbjct: 78  SPRGGARRRGELPRDSRARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYF 137

Query: 116 LVQGLVE 122
            +  LV+
Sbjct: 138 QLTDLVK 144


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 62.4 bits (150), Expect = 5e-10
 Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 5/93 (5%)

Query: 31  SKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILN 89
           S  V+LNVGG  + TT+ TL K   + L  MFS   +  TD+EG   IDR   +F  IL+
Sbjct: 32  STVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILD 91

Query: 90  YLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122
           YLR G VP     + I E+  EA++Y ++ LV+
Sbjct: 92  YLRTGQVP----TQHIPEVYREAQFYEIKPLVK 120


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 39/103 (37%), Positives = 60/103 (58%), Gaps = 3/103 (2%)

Query: 32  KYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSG-RMEVLTDSEGWILIDRCGKHFGTILN 89
           K+V+LNVGG ++ TT QTL + Q + L  +  G  ++   D  G  LIDR   +FG ILN
Sbjct: 31  KWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILN 90

Query: 90  YLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKD 132
           +LR G + L +   E E +L EA++Y +  L+   +  ++ KD
Sbjct: 91  FLRHGKLVLDKDMAE-EGVLEEAEFYNIGPLIRIIKDRMEEKD 132


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 51/192 (26%), Positives = 88/192 (45%), Gaps = 11/192 (5%)

Query: 34  VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92
           ++LNVGG +Y    ++L + +D+ML +MFSGR  + TD  G  +IDR G+ F  +L+YL 
Sbjct: 14  LRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDYLH 73

Query: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPV---ITSSKEE 149
            G V +P   +    L  EA Y+ +              +TY     + +   +T   + 
Sbjct: 74  -GEVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSLRSNIELKKALTDFCDS 132

Query: 150 QKLIATSNKPAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRV----LFIKD 205
             L+   NKP V +L+  + +  S  S          +  D +  +  GR+    +F ++
Sbjct: 133 YGLVC--NKPTVWVLHYLNTSGASCESRIIGVYATKTDGTDAIEKQLGGRIHSKGIFKRE 190

Query: 206 VIGDEICCWSFY 217
              +    WS+Y
Sbjct: 191 AGNNVQYIWSYY 202


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 42/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)

Query: 4   MSGESVVSSAV-PAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMF 61
           MS  S+  S V P AA         + S+  V ++VGG +Y +++ TLTK  D+ +  +F
Sbjct: 27  MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86

Query: 62  SGRMEVLTDS-EGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL 120
           +G   ++ DS +    IDR G+ F  +L++LR   + LP+  ++   L  EA+YY +Q +
Sbjct: 87  NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146

Query: 121 VEECQAALQNKD 132
           V E +   Q ++
Sbjct: 147 VRELERWQQEQE 158


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 42/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)

Query: 4   MSGESVVSSAV-PAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMF 61
           MS  S+  S V P AA         + S+  V ++VGG +Y +++ TLTK  D+ +  +F
Sbjct: 27  MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86

Query: 62  SGRMEVLTDS-EGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL 120
           +G   ++ DS +    IDR G+ F  +L++LR   + LP+  ++   L  EA+YY +Q +
Sbjct: 87  NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146

Query: 121 VEECQAALQNKD 132
           V E +   Q ++
Sbjct: 147 VRELERWQQEQE 158


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 42/132 (31%), Positives = 72/132 (54%), Gaps = 3/132 (2%)

Query: 4   MSGESVVSSAV-PAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMF 61
           MS  S+  S V P AA         + S+  V ++VGG +Y +++ TLTK  D+ +  +F
Sbjct: 27  MSRLSLTRSPVSPLAAQGIPLPAQLTKSNAPVHIDVGGHMYTSSLATLTKYPDSRISRLF 86

Query: 62  SGRMEVLTDS-EGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGL 120
           +G   ++ DS +    IDR G+ F  +L++LR   + LP+  ++   L  EA+YY +Q +
Sbjct: 87  NGTEPIVLDSLKQHYFIDRDGEIFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPM 146

Query: 121 VEECQAALQNKD 132
           V E +   Q ++
Sbjct: 147 VRELERWQQEQE 158


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 36/106 (33%), Positives = 62/106 (58%), Gaps = 4/106 (3%)

Query: 31  SKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDSE--GWILIDRCGKHFGTI 87
           SK+V+LNVGG  + TT QTL +   + L  +     ++ +D +  G  LIDR   +FG +
Sbjct: 43  SKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPV 102

Query: 88  LNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDT 133
           LNYLR G + + +   E E +L EA++Y +  L++  +  ++ +D+
Sbjct: 103 LNYLRHGKLVINKDLAE-EGVLEEAEFYNITSLIKLVKDKIRERDS 147


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 46/151 (30%), Positives = 73/151 (48%), Gaps = 16/151 (10%)

Query: 15  PAAATRTTSFKGTSP--------SSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRME 66
           PAAA       G  P        ++++V+LNVGG  + TT QTL ++          + +
Sbjct: 47  PAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQED 106

Query: 67  VLTDSE----GWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122
              DS+    G  LIDR   +FG ILNYLR G + + +   E E +L EA++Y +  LV 
Sbjct: 107 PELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAE-EGVLEEAEFYNIASLVR 165

Query: 123 ECQAAL---QNKDTYEPFCKVPVITSSKEEQ 150
             +  +   +N+ +  P   V  +   +EE+
Sbjct: 166 LVKERIRDNENRTSQGPVKHVYRVLQCQEEE 196


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 57.8 bits (138), Expect = 1e-08
 Identities = 41/111 (36%), Positives = 53/111 (47%), Gaps = 3/111 (2%)

Query: 16  AAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGW 74
           AAAT         P  + + LNVGG  + T+ QTLT   D+   ++ SGR+  L D  G 
Sbjct: 3   AAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGA 62

Query: 75  ILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQ 125
           I IDR    F  ILN+LR     L         LL EA++Y +  LV   Q
Sbjct: 63  IFIDRDPTVFAPILNFLR--TKELDPRGVHGSSLLHEAQFYGLTPLVRRLQ 111


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 34/106 (32%), Positives = 63/106 (59%), Gaps = 2/106 (1%)

Query: 30  SSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDS-EGWILIDRCGKHFGTI 87
           S+  V ++VGG +Y +++ TLTK  ++ +  +F G   ++ DS +    IDR G+ F  I
Sbjct: 636 SNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYI 695

Query: 88  LNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDT 133
           LN+LR   + +P+  ++   L  EAKY+ +Q ++ E +   Q+++T
Sbjct: 696 LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRET 741


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 34/106 (32%), Positives = 63/106 (59%), Gaps = 2/106 (1%)

Query: 30  SSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDS-EGWILIDRCGKHFGTI 87
           S+  V ++VGG +Y +++ TLTK  ++ +  +F G   ++ DS +    IDR G+ F  I
Sbjct: 28  SNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYI 87

Query: 88  LNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDT 133
           LN+LR   + +P+  ++   L  EAKY+ +Q ++ E +   Q+++T
Sbjct: 88  LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRET 133


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 34/106 (32%), Positives = 63/106 (59%), Gaps = 2/106 (1%)

Query: 30  SSKYVKLNVGGALYYTTMQTLTKQ-DTMLKAMFSGRMEVLTDS-EGWILIDRCGKHFGTI 87
           S+  V ++VGG +Y +++ TLTK  ++ +  +F G   ++ DS +    IDR G+ F  I
Sbjct: 28  SNAPVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYI 87

Query: 88  LNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDT 133
           LN+LR   + +P+  ++   L  EAKY+ +Q ++ E +   Q+++T
Sbjct: 88  LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPMLLEMERWKQDRET 133


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 38/94 (40%), Positives = 52/94 (55%), Gaps = 5/94 (5%)

Query: 34  VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTD----SEGWILIDRCGKHFGTIL 88
           V+LNVGG +Y+T   TL     ++L  MFS + +   D    S+G   IDR G  F  IL
Sbjct: 27  VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122
           +YLRD  V LP+   E   L  EA+Y+ +  LV+
Sbjct: 87  DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 44/135 (32%), Positives = 68/135 (50%), Gaps = 10/135 (7%)

Query: 33  YVKLNVGGALYYTTMQTLTKQ--DTMLKAMFS--GRMEVLTDSEGWILIDRCGKHFGTIL 88
           ++ LNVGG  + TT  TL  +  D+ML  MF   G      D  G  LIDR  ++F  IL
Sbjct: 90  WLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEPIL 149

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKE 148
           NYLR G + +      +  +L EA+++ +  L+E  + A++N    E    +    S KE
Sbjct: 150 NYLRHGQL-IVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPI----SRKE 204

Query: 149 EQK-LIATSNKPAVK 162
             + L+AT  K  ++
Sbjct: 205 FVRFLLATPTKSELR 219


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 38/99 (38%), Positives = 54/99 (54%), Gaps = 3/99 (3%)

Query: 34  VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRM--EVLTDSEGWILIDRCGKHFGTILNY 90
           V+LNVGG +Y T   T+    D++L  MF+ +   E+  DS+G   +DR G  F  IL+Y
Sbjct: 36  VELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYILDY 95

Query: 91  LRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQ 129
           LRD  + LP+   E   L  EA+Y+ +  LV    A  Q
Sbjct: 96  LRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQ 134


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)

Query: 33  YVKLNVGGALYYTTMQTLTKQ--DTMLKAMFS--GRMEVLTDSEGWILIDRCGKHFGTIL 88
           ++ L+VGG  + TT  TL  +  D ML  MF   G      D  G  LID+  ++F  IL
Sbjct: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPIL 149

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKE 148
           NYLR G + +     ++  +L EA+++ +  L+E  + A++N    E    +    S KE
Sbjct: 150 NYLRHGQL-IVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPI----SRKE 204

Query: 149 EQK-LIATSNKPAVK 162
             + L+AT  K  ++
Sbjct: 205 FVRCLLATPTKSEMR 219


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)

Query: 33  YVKLNVGGALYYTTMQTLTKQ--DTMLKAMFS--GRMEVLTDSEGWILIDRCGKHFGTIL 88
           ++ L+VGG  + TT  TL  +  D ML  MF   G      D  G  LID+  ++F  IL
Sbjct: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPIL 149

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKE 148
           NYLR G + +     ++  +L EA+++ +  L+E  + A++N    E    +    S KE
Sbjct: 150 NYLRHGQL-IVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPI----SRKE 204

Query: 149 EQK-LIATSNKPAVK 162
             + L+AT  K  ++
Sbjct: 205 FVRCLLATPTKSEMR 219


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 10/135 (7%)

Query: 33  YVKLNVGGALYYTTMQTLTKQ--DTMLKAMFS--GRMEVLTDSEGWILIDRCGKHFGTIL 88
           ++ L+VGG  + TT  TL  +  D ML  MF   G      D  G  LID+  ++F  IL
Sbjct: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEPIL 149

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKE 148
           NYLR G + +     ++  +L EA+++ +  L+E  + A++N    E    +    S KE
Sbjct: 150 NYLRHGQL-IVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPI----SRKE 204

Query: 149 EQK-LIATSNKPAVK 162
             + L+AT  K  ++
Sbjct: 205 FVRCLLATPTKSEMR 219


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 36/93 (38%), Positives = 49/93 (52%), Gaps = 3/93 (3%)

Query: 30  SSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTIL 88
           S + V+LNVGG  + T+ QTL    D+   ++ SGR+  L D  G I IDR    F  IL
Sbjct: 16  SGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPIL 75

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLV 121
           N+LR   + L      I  L  EA++Y +  LV
Sbjct: 76  NFLRTKELDL--RGVSINVLRHEAEFYGITPLV 106


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 30  SSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTIL 88
           S + V LNVGG ++ T   T+ +   + L  M  GR +      G I +DR G  F  IL
Sbjct: 3   SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122
           ++LR   + LP    +   L  EA +Y ++ LV+
Sbjct: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD 96


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 1/94 (1%)

Query: 30  SSKYVKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTIL 88
           S + V LNVGG ++ T   T+ +   + L  M  GR +      G I +DR G  F  IL
Sbjct: 3   SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62

Query: 89  NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122
           ++LR   + LP    +   L  EA +Y ++ LV+
Sbjct: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLVD 96


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.132    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,591,525
Number of Sequences: 37866
Number of extensions: 490188
Number of successful extensions: 1482
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1409
Number of HSP's gapped (non-prelim): 54
length of query: 313
length of database: 18,247,518
effective HSP length: 102
effective length of query: 211
effective length of database: 14,385,186
effective search space: 3035274246
effective search space used: 3035274246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.