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Search of human proteins with 76880478
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|76880478 calcitonin isoform CGRP preproprotein [Homo
sapiens]
(128 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|76880478 calcitonin isoform CGRP preproprotein [Homo sapiens] 247 2e-66
gi|9945304 calcitonin-related polypeptide, beta [Homo sapiens] 214 2e-56
gi|76880484 calcitonin isoform CALCA preproprotein [Homo sapiens] 147 2e-36
gi|4502545 calcitonin isoform CALCA preproprotein [Homo sapiens] 147 2e-36
gi|4557655 islet amyloid polypeptide precursor [Homo sapiens] 43 8e-05
gi|13699803 WAS protein family, member 3 [Homo sapiens] 30 0.39
gi|212549738 anaphase-promoting complex subunit 7 isoform b [Hom... 29 0.88
gi|212549736 anaphase-promoting complex subunit 7 isoform a [Hom... 29 0.88
gi|92110055 histidine decarboxylase [Homo sapiens] 29 0.88
gi|22027541 programmed cell death 7 [Homo sapiens] 28 1.5
gi|239756272 PREDICTED: hypothetical protein XP_002344878 [Homo ... 28 2.6
gi|239750813 PREDICTED: hypothetical protein XP_002347569 [Homo ... 28 2.6
gi|239745173 PREDICTED: hypothetical protein XP_002343380 [Homo ... 28 2.6
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 27 4.4
gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Ho... 27 4.4
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 27 5.7
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 26 7.4
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 26 7.4
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 26 7.4
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 26 7.4
gi|25777647 small conductance calcium-activated potassium channe... 26 7.4
gi|25777645 small conductance calcium-activated potassium channe... 26 7.4
gi|126032350 protein kinase, DNA-activated, catalytic polypeptid... 26 9.7
gi|57013276 tubulin, alpha, ubiquitous [Homo sapiens] 26 9.7
gi|13654237 protein kinase, DNA-activated, catalytic polypeptide... 26 9.7
gi|17986283 tubulin, alpha 1a [Homo sapiens] 26 9.7
gi|31377566 ring finger protein 168 [Homo sapiens] 26 9.7
>gi|76880478 calcitonin isoform CGRP preproprotein [Homo sapiens]
Length = 128
Score = 247 bits (631), Expect = 2e-66
Identities = 128/128 (100%), Positives = 128/128 (100%)
Query: 1 MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ 60
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ
Sbjct: 1 MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ 60
Query: 61 MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG 120
MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG
Sbjct: 61 MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG 120
Query: 121 RRRRDLQA 128
RRRRDLQA
Sbjct: 121 RRRRDLQA 128
>gi|9945304 calcitonin-related polypeptide, beta [Homo sapiens]
Length = 127
Score = 214 bits (544), Expect = 2e-56
Identities = 112/128 (87%), Positives = 121/128 (94%), Gaps = 1/128 (0%)
Query: 1 MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ 60
MGF+KFSPFLALSILVL QAGSL AAPFRSALESSP DPATLS+++ARLLLAALVQDYVQ
Sbjct: 1 MGFRKFSPFLALSILVLYQAGSLQAAPFRSALESSP-DPATLSKEDARLLLAALVQDYVQ 59
Query: 61 MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG 120
MKASEL+QEQE +GS AQKRAC+TATCVTHRLAGLLSRSGG+VK+NFVPTNVGSKAFG
Sbjct: 60 MKASELKQEQETQGSSSAAQKRACNTATCVTHRLAGLLSRSGGMVKSNFVPTNVGSKAFG 119
Query: 121 RRRRDLQA 128
RRRRDLQA
Sbjct: 120 RRRRDLQA 127
>gi|76880484 calcitonin isoform CALCA preproprotein [Homo sapiens]
Length = 141
Score = 147 bits (371), Expect = 2e-36
Identities = 85/125 (68%), Positives = 96/125 (76%), Gaps = 7/125 (5%)
Query: 1 MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ 60
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ
Sbjct: 1 MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ 60
Query: 61 MKASELEQEQEREGSRIIA--QKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKA 118
MKASELEQEQEREGS + + KR + +TC+ ++ + F T +G A
Sbjct: 61 MKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKF-----HTFPQTAIGVGA 115
Query: 119 FGRRR 123
G++R
Sbjct: 116 PGKKR 120
>gi|4502545 calcitonin isoform CALCA preproprotein [Homo sapiens]
Length = 141
Score = 147 bits (371), Expect = 2e-36
Identities = 85/125 (68%), Positives = 96/125 (76%), Gaps = 7/125 (5%)
Query: 1 MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ 60
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ
Sbjct: 1 MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQ 60
Query: 61 MKASELEQEQEREGSRIIA--QKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKA 118
MKASELEQEQEREGS + + KR + +TC+ ++ + F T +G A
Sbjct: 61 MKASELEQEQEREGSSLDSPRSKRCGNLSTCMLGTYTQDFNKF-----HTFPQTAIGVGA 115
Query: 119 FGRRR 123
G++R
Sbjct: 116 PGKKR 120
>gi|4557655 islet amyloid polypeptide precursor [Homo sapiens]
Length = 89
Score = 42.7 bits (99), Expect = 8e-05
Identities = 24/62 (38%), Positives = 31/62 (50%), Gaps = 8/62 (12%)
Query: 61 MKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFG 120
+KA+ +E Q +KR C+TATC T RLA L S TNVGS +G
Sbjct: 20 LKATPIESHQ--------VEKRKCNTATCATQRLANFLVHSSNNFGAILSSTNVGSNTYG 71
Query: 121 RR 122
+R
Sbjct: 72 KR 73
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 30.4 bits (67), Expect = 0.39
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 8/78 (10%)
Query: 18 LQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRI 77
L + +H P A PA P +AR L A ++ +Q+K + ++EQE + +
Sbjct: 414 LSSSPMHGPPVAEAKRQEPAQPPI---SDARSDLLAAIRMGIQLKKVQEQREQEAKREPV 470
Query: 78 IAQKRACDTATCVTHRLA 95
D AT ++ R+A
Sbjct: 471 -----GNDVATILSRRIA 483
>gi|212549738 anaphase-promoting complex subunit 7 isoform b [Homo
sapiens]
Length = 537
Score = 29.3 bits (64), Expect = 0.88
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 8/65 (12%)
Query: 38 DPATLSEDEARLLL-AALVQ--DYVQM---KASELEQEQEREGSRIIAQKRACDTATCVT 91
DP T +++A+ LL AL Q DY++ KA L +EQ+ E + + + + CV
Sbjct: 454 DPVT--QEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVL 511
Query: 92 HRLAG 96
HR+ G
Sbjct: 512 HRILG 516
>gi|212549736 anaphase-promoting complex subunit 7 isoform a [Homo
sapiens]
Length = 599
Score = 29.3 bits (64), Expect = 0.88
Identities = 22/65 (33%), Positives = 35/65 (53%), Gaps = 8/65 (12%)
Query: 38 DPATLSEDEARLLL-AALVQ--DYVQM---KASELEQEQEREGSRIIAQKRACDTATCVT 91
DP T +++A+ LL AL Q DY++ KA L +EQ+ E + + + + CV
Sbjct: 454 DPVT--QEKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDGIALLRNALANQSDCVL 511
Query: 92 HRLAG 96
HR+ G
Sbjct: 512 HRILG 516
>gi|92110055 histidine decarboxylase [Homo sapiens]
Length = 662
Score = 29.3 bits (64), Expect = 0.88
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 7/74 (9%)
Query: 40 ATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLS 99
+T+SE LLAA ++MK SE + ++ +R++A A D A + AGL+S
Sbjct: 148 STVSESTLIALLAARKNKILEMKTSEPDADESCLNARLVAY--ASDQAHSSVEK-AGLIS 204
Query: 100 RSGGVVKNNFVPTN 113
+VK F+P +
Sbjct: 205 ----LVKMKFLPVD 214
>gi|22027541 programmed cell death 7 [Homo sapiens]
Length = 485
Score = 28.5 bits (62), Expect = 1.5
Identities = 15/45 (33%), Positives = 25/45 (55%)
Query: 42 LSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDT 86
L E E R L L + + + ELE++Q +E +I+ QKR ++
Sbjct: 365 LYEAEERALRVMLEGEQEEERKRELEKKQRKEKEKILLQKREIES 409
>gi|239756272 PREDICTED: hypothetical protein XP_002344878 [Homo
sapiens]
Length = 141
Score = 27.7 bits (60), Expect = 2.6
Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
Query: 8 PFLALSILVL----LQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQ 56
P L L +L+ G H APF SA P P T E ++RL L Q
Sbjct: 81 PSLPLGVLITDPLTRHPGHHHPAPFHSAALLVPVKPPTAWEGKSRLARPCLSQ 133
>gi|239750813 PREDICTED: hypothetical protein XP_002347569 [Homo
sapiens]
Length = 141
Score = 27.7 bits (60), Expect = 2.6
Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
Query: 8 PFLALSILVL----LQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQ 56
P L L +L+ G H APF SA P P T E ++RL L Q
Sbjct: 81 PSLPLGVLITDPLTRHPGHHHPAPFHSAALLVPVKPPTAWEGKSRLARPCLSQ 133
>gi|239745173 PREDICTED: hypothetical protein XP_002343380 [Homo
sapiens]
Length = 141
Score = 27.7 bits (60), Expect = 2.6
Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 4/53 (7%)
Query: 8 PFLALSILVL----LQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQ 56
P L L +L+ G H APF SA P P T E ++RL L Q
Sbjct: 81 PSLPLGVLITDPLTRHPGHHHPAPFHSAALLVPVKPPTAWEGKSRLARPCLSQ 133
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 26.9 bits (58), Expect = 4.4
Identities = 20/81 (24%), Positives = 35/81 (43%), Gaps = 6/81 (7%)
Query: 49 LLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACD------TATCVTHRLAGLLSRSG 102
LL+A + YV+ ++ L+Q R G R+ + D + T + R+ + S SG
Sbjct: 223 LLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESG 282
Query: 103 GVVKNNFVPTNVGSKAFGRRR 123
V N V V +++
Sbjct: 283 SPVYVNQVKVRVSDALLEKKK 303
>gi|45827809 mitogen-activated protein kinase kinase kinase 6 [Homo
sapiens]
Length = 1288
Score = 26.9 bits (58), Expect = 4.4
Identities = 17/49 (34%), Positives = 30/49 (61%), Gaps = 5/49 (10%)
Query: 34 SSPADPATLS----EDEARLLLAALVQDYVQMKASELEQEQERE-GSRI 77
+SP + + LS E + R +LAA+++ + A L QEQ++E G+R+
Sbjct: 983 ASPEESSGLSLLHQESKRRAMLAAVLEQELPALAENLHQEQKQEQGARL 1031
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 26.6 bits (57), Expect = 5.7
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Query: 44 EDEARLLLAALVQDYV---QMKASELEQEQERE-GSRIIAQKRACDTATCVTHRLAGLLS 99
EDE LL A +Q + Q +A ELE+E E E +R +K+ + A L+ L
Sbjct: 1144 EDEQ--LLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAAR-ELEELSERLE 1200
Query: 100 RSGGVVKNNFVPTNVGSKAFGRRRRDLQ 127
+GG GR RR+L+
Sbjct: 1201 EAGGASAGQREGCRKREAELGRLRRELE 1228
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 26.2 bits (56), Expect = 7.4
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 39 PATLSE-DEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLA 95
P+TL +AR +L ++ +Q++ E ++EQE + RI D AT ++ R+A
Sbjct: 488 PSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERI-----ENDVATILSRRIA 540
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 26.2 bits (56), Expect = 7.4
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 39 PATLSE-DEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLA 95
P+TL +AR +L ++ +Q++ E ++EQE + RI D AT ++ R+A
Sbjct: 488 PSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERI-----ENDVATILSRRIA 540
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 26.2 bits (56), Expect = 7.4
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 39 PATLSE-DEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLA 95
P+TL +AR +L ++ +Q++ E ++EQE + RI D AT ++ R+A
Sbjct: 488 PSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERI-----ENDVATILSRRIA 540
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 26.2 bits (56), Expect = 7.4
Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 6/58 (10%)
Query: 39 PATLSE-DEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLA 95
P+TL +AR +L ++ +Q++ E ++EQE + RI D AT ++ R+A
Sbjct: 488 PSTLPVISDARSVLLEAIRKGIQLRKVEEQREQEAKHERI-----ENDVATILSRRIA 540
>gi|25777647 small conductance calcium-activated potassium channel
protein 2 isoform b [Homo sapiens]
Length = 231
Score = 26.2 bits (56), Expect = 7.4
Identities = 19/85 (22%), Positives = 37/85 (43%)
Query: 32 LESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVT 91
L S + L++ L+ A Q+ + S+L + E RI+ + +T
Sbjct: 114 LRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSI 173
Query: 92 HRLAGLLSRSGGVVKNNFVPTNVGS 116
H L GL+S++ + +F+ + S
Sbjct: 174 HALPGLISQTIRQQQRDFIEAQMES 198
>gi|25777645 small conductance calcium-activated potassium channel
protein 2 isoform a [Homo sapiens]
Length = 579
Score = 26.2 bits (56), Expect = 7.4
Identities = 19/85 (22%), Positives = 37/85 (43%)
Query: 32 LESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVT 91
L S + L++ L+ A Q+ + S+L + E RI+ + +T
Sbjct: 462 LRSVKMEQRKLNDQANTLVDLAKTQNIMYDMISDLNERSEDFEKRIVTLETKLETLIGSI 521
Query: 92 HRLAGLLSRSGGVVKNNFVPTNVGS 116
H L GL+S++ + +F+ + S
Sbjct: 522 HALPGLISQTIRQQQRDFIEAQMES 546
>gi|126032350 protein kinase, DNA-activated, catalytic polypeptide
isoform 2 [Homo sapiens]
Length = 4097
Score = 25.8 bits (55), Expect = 9.7
Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 7 SPFLALSILVLLQAGSLHAAPFR---SALESSPADPATLSEDEARLLL 51
S +L+ +IL L +R +AL S PA A + ED+AR +L
Sbjct: 3313 SSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
>gi|57013276 tubulin, alpha, ubiquitous [Homo sapiens]
Length = 451
Score = 25.8 bits (55), Expect = 9.7
Identities = 13/29 (44%), Positives = 18/29 (62%)
Query: 46 EARLLLAALVQDYVQMKASELEQEQEREG 74
EAR +AAL +DY ++ +E E E EG
Sbjct: 420 EAREDMAALEKDYEEVGVDSVEGEGEEEG 448
>gi|13654237 protein kinase, DNA-activated, catalytic polypeptide
isoform 1 [Homo sapiens]
Length = 4128
Score = 25.8 bits (55), Expect = 9.7
Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 7 SPFLALSILVLLQAGSLHAAPFR---SALESSPADPATLSEDEARLLL 51
S +L+ +IL L +R +AL S PA A + ED+AR +L
Sbjct: 3313 SSYLSKNILAFRDQNILLGTTYRIIANALSSEPACLAEIEEDKARRIL 3360
>gi|17986283 tubulin, alpha 1a [Homo sapiens]
Length = 451
Score = 25.8 bits (55), Expect = 9.7
Identities = 13/29 (44%), Positives = 18/29 (62%)
Query: 46 EARLLLAALVQDYVQMKASELEQEQEREG 74
EAR +AAL +DY ++ +E E E EG
Sbjct: 420 EAREDMAALEKDYEEVGVDSVEGEGEEEG 448
>gi|31377566 ring finger protein 168 [Homo sapiens]
Length = 571
Score = 25.8 bits (55), Expect = 9.7
Identities = 17/70 (24%), Positives = 34/70 (48%), Gaps = 7/70 (10%)
Query: 56 QDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVG 115
++Y+Q +E E+E++R+ + ++RA + LA LS + NNF ++
Sbjct: 143 EEYIQRLLAEEEEEEKRQAEK---RRRAMEEQLKSDEELARKLS----IDINNFCEGSIS 195
Query: 116 SKAFGRRRRD 125
+ R+ D
Sbjct: 196 ASPLNSRKSD 205
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.131 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,312,884
Number of Sequences: 37866
Number of extensions: 157989
Number of successful extensions: 641
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 627
Number of HSP's gapped (non-prelim): 28
length of query: 128
length of database: 18,247,518
effective HSP length: 90
effective length of query: 38
effective length of database: 14,839,578
effective search space: 563903964
effective search space used: 563903964
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.