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Search of human proteins with 7661990
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661990 mastermind-like 1 [Homo sapiens]
(1016 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661990 mastermind-like 1 [Homo sapiens] 2053 0.0
gi|38158015 mastermind-like 3 [Homo sapiens] 514 e-145
gi|33286444 mastermind-like 2 [Homo sapiens] 187 6e-47
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 72 3e-12
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 72 3e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 72 3e-12
gi|119943102 CREB binding protein isoform b [Homo sapiens] 70 1e-11
gi|119943104 CREB binding protein isoform a [Homo sapiens] 70 1e-11
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 69 2e-11
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 67 9e-11
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 65 4e-10
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 65 4e-10
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 59 3e-08
gi|56549696 E1A binding protein p400 [Homo sapiens] 57 9e-08
gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 57 9e-08
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 56 2e-07
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 56 2e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 55 3e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 55 3e-07
gi|27886520 nuclear factor of activated T-cells 5 isoform a [Hom... 55 3e-07
gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo... 55 3e-07
gi|164419746 nuclear factor of activated T-cells 5 isoform d [Ho... 55 3e-07
gi|164419744 nuclear factor of activated T-cells 5 isoform b [Ho... 55 3e-07
gi|27886524 nuclear factor of activated T-cells 5 isoform a [Hom... 55 3e-07
gi|55956910 meningioma 1 [Homo sapiens] 55 4e-07
gi|162951884 R3H domain containing 2 [Homo sapiens] 55 4e-07
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 54 7e-07
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 54 7e-07
gi|110347429 mediator complex subunit 12 [Homo sapiens] 54 7e-07
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 54 7e-07
>gi|7661990 mastermind-like 1 [Homo sapiens]
Length = 1016
Score = 2053 bits (5318), Expect = 0.0
Identities = 1016/1016 (100%), Positives = 1016/1016 (100%)
Query: 1 MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH 60
MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH
Sbjct: 1 MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH 60
Query: 61 QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS 120
QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS
Sbjct: 61 QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS 120
Query: 121 PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS 180
PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS
Sbjct: 121 PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS 180
Query: 181 LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL 240
LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL
Sbjct: 181 LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL 240
Query: 241 MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT 300
MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT
Sbjct: 241 MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT 300
Query: 301 EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS 360
EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS
Sbjct: 301 EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS 360
Query: 361 PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP 420
PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP
Sbjct: 361 PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP 420
Query: 421 APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP 480
APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
Sbjct: 421 APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP 480
Query: 481 YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM 540
YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM
Sbjct: 481 YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM 540
Query: 541 AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV 600
AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV
Sbjct: 541 AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV 600
Query: 601 SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ 660
SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ
Sbjct: 601 SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ 660
Query: 661 QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP 720
QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP
Sbjct: 661 QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP 720
Query: 721 MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH 780
MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH
Sbjct: 721 MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH 780
Query: 781 IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ 840
IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ
Sbjct: 781 IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ 840
Query: 841 HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG 900
HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG
Sbjct: 841 HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG 900
Query: 901 SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA 960
SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA
Sbjct: 901 SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA 960
Query: 961 YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ 1016
YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
Sbjct: 961 YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ 1016
>gi|38158015 mastermind-like 3 [Homo sapiens]
Length = 1133
Score = 514 bits (1323), Expect = e-145
Identities = 384/1110 (34%), Positives = 560/1110 (50%), Gaps = 149/1110 (13%)
Query: 12 ALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRA 71
A+P+HS V+ERLR+RIE CRRHH CE RY+ E+LELER+ T +L+QR ++ +AK++
Sbjct: 66 AVPKHSTVVERLRQRIEGCRRHHVNCENRYQQAQVEQLELERRDTVSLYQRTLEQRAKKS 125
Query: 72 GKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQNGDQQNGY- 130
G P+ P +AA + L +TVKR L+ A SP NGDQQNG
Sbjct: 126 GAG----TGKQQHPSKPQQDAEAASAEQRNHTLIMLQETVKRKLEGARSPLNGDQQNGAC 181
Query: 131 -GDLFPGHKKTRREAPLGVAISSN-----GLPPASPLGQSD-KPSGADALQSSGKHSLGL 183
G+ P K+ R++ G+ +N LP ASPL Q D KPS LQ+SG H+ GL
Sbjct: 182 DGNFSPTSKRIRKDISAGMEAINNLPSNMPLPSASPLHQLDLKPSLP--LQNSGTHTPGL 239
Query: 184 -DSLNKK-RLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLM 241
+ L+K RL + L +NG S+ +SF + +K+LKQEP++D C+ T +Q+ L
Sbjct: 240 LEDLSKNGRLPEIKLPVNGCSDLEDSFTILQSKDLKQEPLDDPTCIDTSETSLSNQNKLF 299
Query: 242 PDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQD-INIKT 300
D+NLN+QEW+ELI+EL +VP++D++DLFNEDFEEKK+PE S AT+TPL+Q+ ++K+
Sbjct: 300 SDINLNDQEWQELIDELANTVPEDDIQDLFNEDFEEKKEPEFSQPATETPLSQESASVKS 359
Query: 301 EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS 360
+ S + F +GSPQ R S+G F S+ +T PS+ + P A NP+
Sbjct: 360 DPSHSPFAHVSMGSPQARPSSSGPPF---STVSTATSLPSVAST---------PAAPNPA 407
Query: 361 PNLMPASAQAQNAQRA----LAGVVLPSQGPG--------------------GASELSSA 396
+ PA+ Q+ Q G P G G +S++S A
Sbjct: 408 SS--PANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMSPA 465
Query: 397 HQLQQIAA---------------KQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLD 441
QL+Q+AA +Q+++Q Q QQ Q S W GP S
Sbjct: 466 EQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYG 525
Query: 442 VPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQN 501
+ EKP SP Y Q F N ++ P N YL +H+N+++ Q P+NL N
Sbjct: 526 AAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQ-PNNLGTN 584
Query: 502 SANNQGSVLDYGNTKPLSHYKADCGQ--GSPGSGQSKPALMAYLPQQ------------- 546
S N Q ++L YGNTKPL+H+ AD Q P + +K LM Y+ QQ
Sbjct: 585 SLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQ 644
Query: 547 -----------LSHISHEQNSLFLMKPK---PGNMPFRSLVPPGQEQNPSSVPVQAQATS 592
+H+S +Q L LMK K M + +L GQEQ+P +P
Sbjct: 645 QQPPPPQLQAPRAHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQ 704
Query: 593 VGTQPPAVSVAS--SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKH---LQQQQFL 647
P + + S S +L SQ QAA+MK Q+L+DQ+ Q +QQK +Q+Q
Sbjct: 705 SSVPPGSGGMVSGASPAGPGFLGSQPQAAIMK--QMLIDQRAQLIEQQKQQFLREQRQQQ 762
Query: 648 QRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFP-QQVGQFTGSS---AAVPGMNTLGP 703
Q+QQ +LAEQ+ Q Q HL P Q+ P + +P QQV QF GS AAV L
Sbjct: 763 QQQQQILAEQQLQ--QSHL---PRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQS 817
Query: 704 SNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGI 763
+S R+ Q +M +GP + ++ T + Q + G+A + + Q +Y M++G+
Sbjct: 818 MRTS--RLMAQNAGMMGIGPSQ-NPGTMATAAAQSEMGLAPY-STTPTSQPGMYNMSTGM 873
Query: 764 TQIVAQPPPQA---TNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQH--NKGTLNP 818
TQ++ P T+ A PRQ GQ + + +GQ+ L +S ++QQH KG +
Sbjct: 874 TQMLQHPNQSGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQ 933
Query: 819 GLTKPPV-PRVSPAMGGQN---SSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQ--QQA 872
L +P PR+ MG SWQ + + + G+T G + PF +S+ +Q Q
Sbjct: 934 ALPRPQAPPRLQSLMGTVQQGAQSWQQRSLQGMPGRTSG--ELGPFNNGASYPLQAGQPR 991
Query: 873 HLKMSSPQ-FSQAVPNR---PMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGL 928
K PQ SQ+V + + ++ AA ++P + QQ TS P +
Sbjct: 992 LTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQMMPSLPGQQGTSQARP--------MVM 1043
Query: 929 PGLSPAGPELGAFSQSPASQM---GGRAGLHCTQAYPVRTAGQELPFAYSGQPGGSGLSS 985
GLS P + AFSQ PA Q G A +QAY R A Q++ + YSG G
Sbjct: 1044 SGLSQGVPGMPAFSQPPAQQQIPSGSFAPSSQSQAYE-RNAPQDVSYNYSGDGAGGSFPG 1102
Query: 986 VAGHTDLIDSLLKNRTSEEWMSDLDDLLGS 1015
+ DL+DS++K +EWM +LD+L G+
Sbjct: 1103 LPDGADLVDSIIKGGPGDEWMQELDELFGN 1132
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 187 bits (474), Expect = 6e-47
Identities = 292/1187 (24%), Positives = 449/1187 (37%), Gaps = 252/1187 (21%)
Query: 16 HSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAK-AKRAGKH 74
HSA++ERLR RI +CR+HH +CE RYE E + ER+ T L + A++AGKH
Sbjct: 33 HSAIVERLRARIAVCRQHHLSCEGRYERGRAESSDRERESTLQLLSLVQHGQGARKAGKH 92
Query: 75 RQPPAATA------PAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQN----- 123
+ A A P PAAP AA P + H + L+S+ + +
Sbjct: 93 TKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNGGSGGING 152
Query: 124 ---------GDQQNGYGDLFPGHKKTRREAPLGVAISS--NGLPPASPLG------QSDK 166
GDQ+N G K ++ L A S NG S L +
Sbjct: 153 EQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDIKRIRVGENL 212
Query: 167 PSGADALQ--------SSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQ 218
+G LQ SG + L K S H G F + L KE+K+
Sbjct: 213 SAGQGGLQINNGQSQIMSGTLPMSQAPLRKTNTLPSHTHSPGNG----LFNMGL-KEVKK 267
Query: 219 EPVEDLPCMITGTVGSISQSNLMPDL-------NLNEQEWKELIEEL-NRSVP---DEDM 267
EP E L C G ++Q N+ P+ L + E +EL EL N SVP D ++
Sbjct: 268 EPGETLSCS-KHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVPPMSDLEL 326
Query: 268 KDLFNEDFEEKKDP------ESSGSATQTPL--AQDINIKTEFSPAAFEQEQLGSPQVRA 319
+++ N ++ DP + S +T P + I IK+E+SP Q GSPQ+R
Sbjct: 327 ENMINATIKQ-DDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSP-GLTQGPSGSPQLRP 384
Query: 320 GSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAG 379
SAG F +SA +ST S P P++ + AQ Q A
Sbjct: 385 PSAGPAFSMANSA-LSTSS--------------------PIPSVPQSQAQPQTGSG--AS 421
Query: 380 VVLPSQGPGGASELSSAHQLQQIAA-KQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHS 438
LPS E+S A QL+QIAA +Q+ +M Q+ QQ P + W S
Sbjct: 422 RALPSW-----QEVSHAQQLKQIAANRQQHARMQQHQQQHQP-------TNWSALPSSAG 469
Query: 439 SLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPR---------PGGPYLQPSHVNL 489
P+ EK SPS +Q F + + MP V S + GP Q H+++
Sbjct: 470 PSPGPFGQEKIPSPSFGQQTF-SPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDV 528
Query: 490 LSHQPPSNLNQNSANNQGSVLD--YGNTKPLSHYKAD-CGQGSPG--SGQSKPALMAYLP 544
L Q P +L+++ NN ++ GNTKPL H+ +D Q P Q+KP+L+ Y
Sbjct: 529 LMQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPSLLHYTQ 588
Query: 545 QQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVAS 604
QQ +Q Q+Q Q Q Q ++S
Sbjct: 589 QQQQQQQQQQQQ--------------------QQQQQQQQQQQQQQQQQQQQQSSISAQQ 628
Query: 605 SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKH---------------------LQQ 643
+S+QQQ +Q Q QQ+Q++QQQ+ LQQ
Sbjct: 629 QQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQ 688
Query: 644 QQFLQRQQ--------HLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAV 695
+ LQ+ Q + +++Q++Q + + P S P + S ++
Sbjct: 689 KLLLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSL 748
Query: 696 PGMNTLGPSNSSCPRVFPQ-------------AGNLMPMGPGHASVSSLPTNSGQQDRGV 742
+G + ++ Q A + P + +S P + Q R V
Sbjct: 749 LNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNV 808
Query: 743 ------AQFP-GSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSA 795
AQ+ GS + +S +A+ ++ P + +H R ++
Sbjct: 809 GNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMG 868
Query: 796 AYG----------QNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSS------- 838
YG + G + L+QQ N L P +PR P +G N++
Sbjct: 869 MYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPR-PPTLGPSNNNNVATFGA 927
Query: 839 ----WQHQGMPNLS-------GQTPGNSNVSPFTAASSFHMQ-----QQAHLKMSSPQF- 881
Q PNL+ Q N ++ T A ++ Q QQ L + +F
Sbjct: 928 GSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFP 987
Query: 882 ------------------SQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAP---- 919
SQ R +AP + + P Q + P
Sbjct: 988 TGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLRGL 1047
Query: 920 ---PPTAPQQGLPGLSPAGPELG----AFSQSPA-SQMGGRAGLHCTQAYPVRTAGQELP 971
P Q LP L+ +G L +Q P+ + + ++A+ +L
Sbjct: 1048 NLRPNQLSTQILPNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQSSRAFQGTDHSSDLA 1107
Query: 972 FAYSGQPGGSGLSSVAGHTDLIDSLLKNRT-SEEWMSD--LDDLLGS 1015
F + Q + ++ D IDSLLK +++WM D LD++LG+
Sbjct: 1108 FDFLSQQNDNMGPALNSDADFIDSLLKTEPGNDDWMKDINLDEILGN 1154
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 72.0 bits (175), Expect = 3e-12
Identities = 148/632 (23%), Positives = 210/632 (33%), Gaps = 122/632 (19%)
Query: 372 NAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP-------APAP 424
++ R G ++ G GGA+ LS A Q+ Q+P ATP +P+P
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
Query: 425 GQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRP-GGPYLQ 483
M ++ + P +SS P P P+ P S + + + G Y
Sbjct: 371 -MMRSYGGSYPEYSSPSAPPP--PPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA 427
Query: 484 PSHVNLLSHQ------PPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKP 537
S + Q P +QGS +D K Y G GS Q
Sbjct: 428 ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLY----GMGSNPHSQ--- 480
Query: 538 ALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQP 597
PQQ S P PG S PPG ++ P + + G Q
Sbjct: 481 ------PQQSS-------------PYPGG----SYGPPGPQRYPIGIQGRTPGAMAGMQY 517
Query: 598 P-----------AVSVASSHNSSPYLSSQQQAAVMK-QHQLLLDQQKQREQQQKHLQQQQ 645
P VS PY S Q Q + Q Q L Q +QR Q Q+ + Q+
Sbjct: 518 PQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG 577
Query: 646 FLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQF----TGSSAAVPGMNTL 701
+ R Q LA + +L Q S P G TG+ A + +
Sbjct: 578 YGTRSQPPLAPGKPNHEDLNLI------QQERPSSLPDLSGSIDDLPTGTEATLSSAVSA 631
Query: 702 GPSNSS------------CPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGV---AQFP 746
S SS P P ++ P GP + V S P S Q G A P
Sbjct: 632 SGSTSSQGDQSNPAQSPFSPHASPHLSSI-PGGPSPSPVGS-PVGSNQSRSGPISPASIP 689
Query: 747 GSQNMPQSSLYGMASGITQIVAQPPPQATNGHA-----------HIPRQTNVGQNTSVSA 795
GSQ PQ S ++Q P G + P+QT + S
Sbjct: 690 GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSP 749
Query: 796 AYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNS 855
GQ G S Q ++ GT P +++ G + + G+P+ S PG
Sbjct: 750 G-GQMHAGISSFQQSNSSGTYGPQMSQ------YGPQGNYSRPPAYSGVPSASYSGPGPG 802
Query: 856 NVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAP 915
M A+ +M SQ P+ M SA P + S+P
Sbjct: 803 ------------MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850
Query: 916 APAPPPTAPQQGLPGLSPAGPELGAFSQSPAS 947
+ QQG PG+ P P + +Q A+
Sbjct: 851 GMS------QQGGPGMGPPMPTVNRKAQEAAA 876
Score = 54.7 bits (130), Expect = 4e-07
Identities = 173/804 (21%), Positives = 285/804 (35%), Gaps = 120/804 (14%)
Query: 276 EEKKDPESSGSATQTPLA------QDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGP 329
++ E G+ +Q PLA +D+N+ + P++ + G+
Sbjct: 570 QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 629
Query: 330 S-SAPVSTDSPSLGGSQTLF------HTSGQPRADNPSPNLMPASAQAQNA----QRALA 378
S S S+ +Q+ F H S P +PSP P + + ++
Sbjct: 630 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIP 689
Query: 379 GVVLPSQGPGGASELSSAHQLQQIAAKQKREQML---QNPQQATPAPAPGQMSTWQQTGP 435
G +P Q PG SE SS L Q Q+R M +NPQ A P QQTGP
Sbjct: 690 GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP--------QQTGP 741
Query: 436 SHSSLDVPYPM---EKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQP---SHVNL 489
S S P+P + A SS++Q +NS P +++ P+ G Y +P S V
Sbjct: 742 SMS----PHPSPGGQMHAGISSFQQ--SNSSGTYGPQMSQYGPQ--GNYSRPPAYSGVPS 793
Query: 490 LSHQPPSNLNQNSANNQ---------------GSVLDYG-NTKPLSHYKADCGQGSPGSG 533
S+ P SANNQ G + G +P + SPG
Sbjct: 794 ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853
Query: 534 QSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQ-------NPSSVPV 586
Q M P + ++ + +M+ + R PG Q +P S P+
Sbjct: 854 QQGGPGMG-PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPM 912
Query: 587 QAQATSVGTQPPAVSVASSH-NSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQ 645
++ + TQ P S+A + NSS +S A +M + L + + +++ Q +
Sbjct: 913 NNSSSLMNTQAPPYSMAPAMVNSS--AASVGLADMMSPGESKLPLPLKADGKEEGTPQPE 970
Query: 646 FLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPG--MNTLGP 703
+ + + Q Q P P P+ S G S + PG P
Sbjct: 971 SKSKDSY--SSQGISQPPTPGNLPVPSPMSPSSASISSFHGD-ESDSISSPGWPKTPSSP 1027
Query: 704 SNSSCPRVFPQAGNLMPMG---PGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMA 760
+SS + + +G V T ++ V+ P P L+ +
Sbjct: 1028 KSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKP-LDLFRLY 1086
Query: 761 SGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLG-------SSGLSQQHNK 813
+ +I + NVG ++S +++ + + ++
Sbjct: 1087 VCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPP 1146
Query: 814 GTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSG-----QTPGNSNVSPFTAASSFHM 868
+ G TK P++ P + S Q P +G + PG ++ P T AS+ H
Sbjct: 1147 EVFSTGDTKKQ-PKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPG--DLKPPTPASTPHG 1203
Query: 869 QQQAHLKMSSPQFSQAVPNRPMAPMSSAA--AVGSLLPPVSAQQRTSAP--------APA 918
Q M + S + P + +S ++ S+ P QQ S P P
Sbjct: 1204 QM---TPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPN 1260
Query: 919 PPPTAPQQGLPGLS---------PAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTA--G 967
P + +PG S P ++QSP+ M G+ Q +P +
Sbjct: 1261 KDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAM-SNLGMGQRQQFPYGASYDR 1319
Query: 968 QELPFA--YSGQPGGSGLSSVAGH 989
+ P+ Y GQ SG GH
Sbjct: 1320 RHEPYGQQYPGQGPPSGQPPYGGH 1343
Score = 46.2 bits (108), Expect = 2e-04
Identities = 87/427 (20%), Positives = 134/427 (31%), Gaps = 68/427 (15%)
Query: 605 SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHL---------------QQQQFLQR 649
+H+ + + QQQ +Q Q QQ+Q++QQQ+H Q +++
Sbjct: 39 AHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQ 98
Query: 650 QQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLG------- 702
QH A+ Q PP + + P ++G+ G PG+ LG
Sbjct: 99 PQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVA 158
Query: 703 -PSNSSCPRVFPQAGNLMPM------GPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSS 755
P P P+ N GPG + + GQQ G+ G + ++
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGM----GMMHSASAA 214
Query: 756 LYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNS-LGSSGLSQQHNKG 814
G + + + H P + G G G G G
Sbjct: 215 AAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAG 274
Query: 815 TLNPGLTKPPVPRVSPAMGGQN--------------SSWQHQGMPNLSGQTPGN----SN 856
G + A GG SS + QG + G G S
Sbjct: 275 GAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334
Query: 857 VSPFTAASSFHM--QQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSA 914
+ +AA F Q H ++P +Q + + P + G P S+
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTS----PSPMMRSYGGSYPEYSS------ 384
Query: 915 PAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQEL--PF 972
P+ PP P Q + AG G + +G G A P A Q+ P
Sbjct: 385 --PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA 442
Query: 973 AYSGQPG 979
G PG
Sbjct: 443 MSPGTPG 449
Score = 41.6 bits (96), Expect = 0.004
Identities = 70/283 (24%), Positives = 104/283 (36%), Gaps = 48/283 (16%)
Query: 744 QFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLG 803
Q+P Q PQ G+ SG Q QP H+P Q + S Q +
Sbjct: 516 QYPQQQMPPQYGQQGV-SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574
Query: 804 SSGLSQQHNKGTLNPG--------LTKPPVPRVSPAMGGQ------------NSSWQHQG 843
G + ++ L PG L + P P + G +S+ G
Sbjct: 575 QEGYGTR-SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASG 633
Query: 844 MPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMA-PMSSAAAVGSL 902
+ G N SPF+ +S H+ SP S N+ + P+S A+ GS
Sbjct: 634 STSSQGDQ-SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQ 692
Query: 903 LPPV---SAQQRTSAPAPAPPPTAPQQGL-------PGLSPAGPELGAFSQSPASQMGGR 952
+PP S + +S PA + P ++G P ++ GP+ S SP GG+
Sbjct: 693 MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQ 752
Query: 953 --AGLHC-TQAYPVRTAGQEL-----------PFAYSGQPGGS 981
AG+ Q+ T G ++ P AYSG P S
Sbjct: 753 MHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS 795
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 72.0 bits (175), Expect = 3e-12
Identities = 148/632 (23%), Positives = 210/632 (33%), Gaps = 122/632 (19%)
Query: 372 NAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP-------APAP 424
++ R G ++ G GGA+ LS A Q+ Q+P ATP +P+P
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
Query: 425 GQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRP-GGPYLQ 483
M ++ + P +SS P P P+ P S + + + G Y
Sbjct: 371 -MMRSYGGSYPEYSSPSAPPP--PPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA 427
Query: 484 PSHVNLLSHQ------PPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKP 537
S + Q P +QGS +D K Y G GS Q
Sbjct: 428 ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLY----GMGSNPHSQ--- 480
Query: 538 ALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQP 597
PQQ S P PG S PPG ++ P + + G Q
Sbjct: 481 ------PQQSS-------------PYPGG----SYGPPGPQRYPIGIQGRTPGAMAGMQY 517
Query: 598 P-----------AVSVASSHNSSPYLSSQQQAAVMK-QHQLLLDQQKQREQQQKHLQQQQ 645
P VS PY S Q Q + Q Q L Q +QR Q Q+ + Q+
Sbjct: 518 PQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEG 577
Query: 646 FLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQF----TGSSAAVPGMNTL 701
+ R Q LA + +L Q S P G TG+ A + +
Sbjct: 578 YGTRSQPPLAPGKPNHEDLNLI------QQERPSSLPDLSGSIDDLPTGTEATLSSAVSA 631
Query: 702 GPSNSS------------CPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGV---AQFP 746
S SS P P ++ P GP + V S P S Q G A P
Sbjct: 632 SGSTSSQGDQSNPAQSPFSPHASPHLSSI-PGGPSPSPVGS-PVGSNQSRSGPISPASIP 689
Query: 747 GSQNMPQSSLYGMASGITQIVAQPPPQATNGHA-----------HIPRQTNVGQNTSVSA 795
GSQ PQ S ++Q P G + P+QT + S
Sbjct: 690 GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSP 749
Query: 796 AYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNS 855
GQ G S Q ++ GT P +++ G + + G+P+ S PG
Sbjct: 750 G-GQMHAGISSFQQSNSSGTYGPQMSQ------YGPQGNYSRPPAYSGVPSASYSGPGPG 802
Query: 856 NVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAP 915
M A+ +M SQ P+ M SA P + S+P
Sbjct: 803 ------------MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSP 850
Query: 916 APAPPPTAPQQGLPGLSPAGPELGAFSQSPAS 947
+ QQG PG+ P P + +Q A+
Sbjct: 851 GMS------QQGGPGMGPPMPTVNRKAQEAAA 876
Score = 57.0 bits (136), Expect = 9e-08
Identities = 177/829 (21%), Positives = 280/829 (33%), Gaps = 164/829 (19%)
Query: 276 EEKKDPESSGSATQTPLA------QDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGP 329
++ E G+ +Q PLA +D+N+ + P++ + G+
Sbjct: 570 QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 629
Query: 330 S-SAPVSTDSPSLGGSQTLF------HTSGQPRADNPSPNLMPASAQAQNA----QRALA 378
S S S+ +Q+ F H S P +PSP P + + ++
Sbjct: 630 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIP 689
Query: 379 GVVLPSQGPGGASELSSAHQLQQIAAKQKREQML---QNPQQATPAPAPGQMSTWQQTGP 435
G +P Q PG SE SS L Q Q+R M +NPQ A P QQTGP
Sbjct: 690 GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP--------QQTGP 741
Query: 436 SHSSLDVPYPM---EKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQP---SHVNL 489
S S P+P + A SS++Q +NS P +++ P+ G Y +P S V
Sbjct: 742 SMS----PHPSPGGQMHAGISSFQQ--SNSSGTYGPQMSQYGPQ--GNYSRPPAYSGVPS 793
Query: 490 LSHQPPSNLNQNSANNQ---------------GSVLDYG-NTKPLSHYKADCGQGSPGSG 533
S+ P SANNQ G + G +P + SPG
Sbjct: 794 ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 853
Query: 534 QSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQ-------NPSSVPV 586
Q M P + ++ + +M+ + R PG Q +P S P+
Sbjct: 854 QQGGPGMG-PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPM 912
Query: 587 QAQATSVGTQPPAVSVA----SSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQ 642
++ + TQ P S+A +S +S L+ K L K+ Q +
Sbjct: 913 NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESK 972
Query: 643 QQ---------QFLQRQQHLLAEQEKQQF-QRHLT----RPPPQYQDPTQGSFPQQVGQF 688
+ + + + L E E++ + R+LT R P P G P + +
Sbjct: 973 SKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRL 1032
Query: 689 TGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGS 748
+ G+ + + + + + + +G ++ SSL Q
Sbjct: 1033 YVCVKEIGGLAQVNKN-----KKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIER 1087
Query: 749 QNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLS 808
P ++ Q QPP A +G S+ S GS+ ++
Sbjct: 1088 GEEPPPEVFSTGDTKKQPKLQPPSPANSG--------------SLQGPQTPQSTGSNSMA 1133
Query: 809 QQHNKGTLNPGLTKPPVP------RVSPAMGGQNSS------------------------ 838
+ PG KPP P +++P GG++S+
Sbjct: 1134 EV-------PGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPN 1186
Query: 839 ---WQHQGMPNLSGQTPGNSNVSPF-----TAASSFHMQQQAHLKMSSPQF------SQA 884
Q MP++ G+ P N PF SS Q + SS Q S A
Sbjct: 1187 APYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGA 1246
Query: 885 VPNRPMAPMSS---AAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAF 941
+ N M A+ P Q P PP Q PGL P P +
Sbjct: 1247 MSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQ--PGLYPQQPN---Y 1301
Query: 942 SQSPASQMGGRAGLHCTQAYPVRTAG--QELPFAYSGQPGGSGLSSVAG 988
+ G A H Y ++ + QE+ Y G G + G
Sbjct: 1302 KRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQG 1350
Score = 46.2 bits (108), Expect = 2e-04
Identities = 87/427 (20%), Positives = 134/427 (31%), Gaps = 68/427 (15%)
Query: 605 SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHL---------------QQQQFLQR 649
+H+ + + QQQ +Q Q QQ+Q++QQQ+H Q +++
Sbjct: 39 AHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQ 98
Query: 650 QQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLG------- 702
QH A+ Q PP + + P ++G+ G PG+ LG
Sbjct: 99 PQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVA 158
Query: 703 -PSNSSCPRVFPQAGNLMPM------GPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSS 755
P P P+ N GPG + + GQQ G+ G + ++
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGM----GMMHSASAA 214
Query: 756 LYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNS-LGSSGLSQQHNKG 814
G + + + H P + G G G G G
Sbjct: 215 AAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAG 274
Query: 815 TLNPGLTKPPVPRVSPAMGGQN--------------SSWQHQGMPNLSGQTPGN----SN 856
G + A GG SS + QG + G G S
Sbjct: 275 GAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334
Query: 857 VSPFTAASSFHM--QQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSA 914
+ +AA F Q H ++P +Q + + P + G P S+
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTS----PSPMMRSYGGSYPEYSS------ 384
Query: 915 PAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQEL--PF 972
P+ PP P Q + AG G + +G G A P A Q+ P
Sbjct: 385 --PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA 442
Query: 973 AYSGQPG 979
G PG
Sbjct: 443 MSPGTPG 449
Score = 41.6 bits (96), Expect = 0.004
Identities = 70/283 (24%), Positives = 104/283 (36%), Gaps = 48/283 (16%)
Query: 744 QFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLG 803
Q+P Q PQ G+ SG Q QP H+P Q + S Q +
Sbjct: 516 QYPQQQMPPQYGQQGV-SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574
Query: 804 SSGLSQQHNKGTLNPG--------LTKPPVPRVSPAMGGQ------------NSSWQHQG 843
G + ++ L PG L + P P + G +S+ G
Sbjct: 575 QEGYGTR-SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASG 633
Query: 844 MPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMA-PMSSAAAVGSL 902
+ G N SPF+ +S H+ SP S N+ + P+S A+ GS
Sbjct: 634 STSSQGDQ-SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQ 692
Query: 903 LPPV---SAQQRTSAPAPAPPPTAPQQGL-------PGLSPAGPELGAFSQSPASQMGGR 952
+PP S + +S PA + P ++G P ++ GP+ S SP GG+
Sbjct: 693 MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQ 752
Query: 953 --AGLHC-TQAYPVRTAGQEL-----------PFAYSGQPGGS 981
AG+ Q+ T G ++ P AYSG P S
Sbjct: 753 MHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS 795
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 71.6 bits (174), Expect = 3e-12
Identities = 183/762 (24%), Positives = 255/762 (33%), Gaps = 152/762 (19%)
Query: 309 QEQLGSPQVRAGSAGQTFLGPSSAPVSTDSP----SLGGSQTLFHTSGQPRADNPSPNLM 364
Q G P +AG T G + P P +L Q H+ G PS
Sbjct: 3642 QPPQGPPGGQAGGLRLT-PGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFF 3700
Query: 365 PASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQ--IAAKQKREQMLQNPQQATPAP 422
P + + L S GP QLQQ + QK +Q Q QQ
Sbjct: 3701 PGN------------LALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLL 3748
Query: 423 APGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPY- 481
+ QQ GP + P + P S Q +L P P GP
Sbjct: 3749 GQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP--------PQGPQG 3800
Query: 482 -LQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPG----SGQSK 536
L P+ V +L Q P L + Q VL + S A GQG G + Q +
Sbjct: 3801 MLGPAQVAVLQQQHPGALGPQGPHRQ--VLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQ 3858
Query: 537 PALMAYLPQ-QLSHISHEQNSLFLM--KPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSV 593
+ Q ++ +SH Q SL +PK P SL Q+Q +Q Q
Sbjct: 3859 QQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQ-----LQQQQQLQ 3913
Query: 594 GTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHL 653
Q + QQQ + +Q Q L QQ+Q+ QQQ+ QQQQF Q+QQ
Sbjct: 3914 QQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQ-- 3971
Query: 654 LAEQEKQQFQRHLTRPPPQYQDPTQ-----GSFPQQVGQFTGSSAAVPGMNTLGPSNSSC 708
+Q+ + T PQ Q Q G + + F+ A P + G ++
Sbjct: 3972 --QQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNT- 4028
Query: 709 PRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVA 768
V P + GP ++ P G +A PG + SL G S + +
Sbjct: 4029 --VDPAVSSEATEGP--STHQGGPLAIGTTPESMATEPGEV---KPSLSG-DSQLLLVQP 4080
Query: 769 QPPPQATNGHAHIPRQTNVGQNTSVS-------AAYGQNSLGSSG-------------LS 808
QP PQ ++ P + Q VS ++GQ GSS +S
Sbjct: 4081 QPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVS 4140
Query: 809 QQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQH-----------QGMPN---------LS 848
G++ L P P + M QN++ QG+P L
Sbjct: 4141 LGDQPGSMTQNLLGPQQPMLERPM--QNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLR 4198
Query: 849 GQTPGNSNVSPFTAASSFHMQQQ--AHLKMSSPQFSQAVPNRP--MAPMSSAAAVGSLL- 903
Q G +P S QQQ A L Q SQAV P P + + + LL
Sbjct: 4199 AQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLG 4258
Query: 904 ----------------------PPVSAQQRTSAPA-------------PAPPPTAPQQGL 928
P R AP P PPP++PQ+
Sbjct: 4259 CQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQE-- 4316
Query: 929 PGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQEL 970
P+ + SP+SQ+ A L T + G L
Sbjct: 4317 -------PKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTL 4351
Score = 50.8 bits (120), Expect = 6e-06
Identities = 192/889 (21%), Positives = 294/889 (33%), Gaps = 184/889 (20%)
Query: 143 EAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNGGS 202
EAPL + P SPL + S + + S + L L ++ LHL S
Sbjct: 431 EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEA-LHL---S 486
Query: 203 NPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSV 262
P E PLS E + P+ P + + +S L P E+ E S
Sbjct: 487 RPLEESPLSPPPE--ESPLSPPP--ESSPFSPLEESPLSPP----EESPPSPALETPLSP 538
Query: 263 PDEDMKDLFNEDFEEK--KDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLG-SPQVRA 319
P E + FEE P + P A ++ E SP + E+ SP A
Sbjct: 539 PPEASP--LSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596
Query: 320 GSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRAD--NPSPNLMPASAQAQNAQRAL 377
F +P +SP S P A +P P P S + +
Sbjct: 597 SRLFPPFEESPLSPPPEESP----------LSPPPEASRLSPPPEDSPMSPPPEES---- 642
Query: 378 AGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSH 437
P P S LS + +++ + + P+++ +P P + + P
Sbjct: 643 -----PMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP---EASRLSPPPE 694
Query: 438 SSLDVPYPMEKPASP----SSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQ 493
S P P + PASP S S LL +P + PR GP+L P H
Sbjct: 695 DSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE--PHL 752
Query: 494 PPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHE 553
P +P + + + S Q + + +P++ H+S +
Sbjct: 753 SP--------------------RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE-PHLSPQ 791
Query: 554 QNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLS 613
L P+P + L P +E + S VP + + P S S + P LS
Sbjct: 792 AEGPHL-SPQPEEL---HLSPQTEEPHLSPVPEEPCL----SPQPEESHLSPQSEEPCLS 843
Query: 614 SQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPP--- 670
+ + + HL E EK +PP
Sbjct: 844 PRPE--------------------------------ESHLSPELEKPPLSPRPEKPPEEP 871
Query: 671 ---------PQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGP----SNSSCPRVFPQAGN 717
P + P + S +G+ S P ++ L S S P + PQ
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP 931
Query: 718 LMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNG 777
P+ P + + + G ++P +A+ I + PPP+A
Sbjct: 932 PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEA--- 988
Query: 778 HAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSP----AMG 833
N V S GS G +P L +P P+ SP ++
Sbjct: 989 --------NCTDPEPVPPMILPPSPGSP-------VGPASPILMEPLPPQCSPLLQHSLV 1033
Query: 834 GQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPM 893
QNS P L P S +SP + + H +M + + S+ P P
Sbjct: 1034 PQNSPPSQCSPPALPLSVP--SPLSPIGKVVGVSDEAELH-EMETEKVSE-----PECPA 1085
Query: 894 SSAAAVGSLLPPVSAQQRTSAPAPAPPP-----------TAPQQGL--PGLSPAGPELGA 940
+A L P+ S PAP+P P TAP G+ PG + PE G
Sbjct: 1086 LEPSATSPLPSPMG---DLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG---SQPEPGQ 1139
Query: 941 FSQSPASQMGGR---------AGLHCTQAYP--VRTAGQELPFAYSGQP 978
S AS++ G A + + YP +TAGQ P +P
Sbjct: 1140 TPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEP 1188
Score = 43.5 bits (101), Expect = 0.001
Identities = 160/690 (23%), Positives = 234/690 (33%), Gaps = 127/690 (18%)
Query: 298 IKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSA---PVSTDSPSLGGSQTLFHT--SG 352
+ + PA +Q+Q + + GP+ A P SPSL GSQ +G
Sbjct: 3266 LSAQLQPAQQQQQQQQQHSLLSAP------GPAQAMSLPHEGSSPSLAGSQQQLSLGLAG 3319
Query: 353 QPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQ-IAAKQKREQM 411
+ P P LMP A Q+ LA + G LS H Q + +Q + +
Sbjct: 3320 ARQPGLPQP-LMPTQPPAHALQQRLAPSMAMVSNQGHM--LSGQHGGQAGLVPQQSSQPV 3376
Query: 412 LQNPQQATPAPA----PGQMSTWQQTGPSH---SSLDVPYPMEKPASPSSYKQDFTNSKL 464
L T P+ P Q++ QQ S + LD + E P +K+
Sbjct: 3377 LSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLD-KFAAEDIIDP------IAKAKM 3429
Query: 465 LMMPSVNKSSPRPG---GPYLQPSHVNLLSHQ----PPSNLNQNSANNQGSVLDYGNTKP 517
+ + + K + P + V+LL+ + P S+L + A G G+
Sbjct: 3430 VALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQ 3489
Query: 518 LSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQ 577
QG + Q + H Q L M+ K + +
Sbjct: 3490 PRPNPPTFAQGVINEADQR--------QYEEWLFHTQQ-LLQMQLKV----LEEQIGVHR 3536
Query: 578 EQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQ---- 633
+ + Q A G + P L ++QQ+ + KQ + QQK+
Sbjct: 3537 KSRKALCAKQRTAKKAGREFPEADAEKLK-----LVTEQQSKIQKQLDQVRKQQKEHTNL 3591
Query: 634 ----REQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQY-----QDPTQGSFPQQ 684
R +QQ+ QQQQ Q+Q + Q R LT+ P Q P QG Q
Sbjct: 3592 MAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQ 3651
Query: 685 VG--QFTGSSAAVPG------MNT-----------------LGPSNSSCPRVFPQAGNLM 719
G + T A+PG +NT GPS FP L
Sbjct: 3652 AGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGG----FFPGNLALR 3707
Query: 720 PMGPGHASVSSLPTNSGQQDRGVA---QFPGSQNMPQSSLYGMASGITQIVAQPPPQATN 776
+GP + QQ +A Q Q Q L G + I Q Q P TN
Sbjct: 3708 SLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVA-IQQQQQQGPGVQTN 3766
Query: 777 ------GHAHIPRQTNVG---QNTSVSAAYG-QNSLGSSGLS--QQHNKGTLNPGLTKPP 824
+P ++ G Q S G Q LG + ++ QQ + G L P + P
Sbjct: 3767 QALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGP---QGP 3823
Query: 825 VPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSS----PQ 880
+V SS P L+ Q G TA QQQ H + S
Sbjct: 3824 HRQVLMTQSRVLSS------PQLAQQGQGLMGHRLVTAQQ--QQQQQQHQQQGSMAGLSH 3875
Query: 881 FSQAVPNRPMAPMSSAAAVGSLLPPVSAQQ 910
Q++ + P SA +GSL QQ
Sbjct: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQ 3905
Score = 35.0 bits (79), Expect = 0.36
Identities = 33/126 (26%), Positives = 49/126 (38%), Gaps = 5/126 (3%)
Query: 608 SSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLT 667
S L + + V + LL++ E ++K LQ++Q L Q +Q++QQ Q L
Sbjct: 3229 SGDELDKMESSLVASELPLLIEDL--LEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLL 3286
Query: 668 RPPPQYQD---PTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPG 724
P Q P +GS P G S + G G P P + P
Sbjct: 3287 SAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPS 3346
Query: 725 HASVSS 730
A VS+
Sbjct: 3347 MAMVSN 3352
Score = 35.0 bits (79), Expect = 0.36
Identities = 64/237 (27%), Positives = 83/237 (35%), Gaps = 41/237 (17%)
Query: 283 SSGSATQTP--LAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSS---APVSTD 337
SS A+ P LAQ ++ P + Q LG Q Q GP PV
Sbjct: 4123 SSSEASSVPHLLAQP-SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQS 4181
Query: 338 SPSLGGSQTLFHTSGQPRAD-----NPSPNLMPASAQAQNA------QRALAGVVLPSQG 386
L G + T GQ RA +P L S Q Q QR L Q
Sbjct: 4182 GQGLPGVG-IMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQT 4240
Query: 387 PGGASELSSAHQLQQIAAKQKREQMLQNPQQAT----------------PAPAPGQMSTW 430
P + LQ + Q + PQ PAP PG +ST
Sbjct: 4241 PPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP-PGALSTG 4299
Query: 431 QQTGPSHSSLDVPYPME--KPAS-PSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQP 484
GP H + P E +P+ PS Q T ++L P + +P+P GP L+P
Sbjct: 4300 PVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQL---PPTHPGTPKPQGPTLEP 4353
Score = 32.3 bits (72), Expect = 2.3
Identities = 71/276 (25%), Positives = 94/276 (34%), Gaps = 55/276 (19%)
Query: 712 FPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQI---VA 768
FP A P G HA V S + + G F G+ + P + A G + V
Sbjct: 2494 FPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPS-PMRFTFPQAVGEPSLKPPVP 2552
Query: 769 QP---PPQATNGHAHIPRQTNVGQNTSVSAAYGQ------------NSLGSS-GLSQQHN 812
QP PP N H Q+T+ + A G S G S GLS
Sbjct: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612
Query: 813 KGTLNP------------------GLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGN 854
L P G+T P R P G SS +P Q PG
Sbjct: 2613 PSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTG-MGSSLATAELPGT--QDPGM 2669
Query: 855 SNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSA 914
S +S T +Q+ + Q + + ++AAA G++ PP S S+
Sbjct: 2670 SGLSQ-TELEKQRQRQRLRELLIRQQIQRNTLRQEKE--TAAAAAGAVGPPGSWGAEPSS 2726
Query: 915 PA-----PAPPPTAPQQ------GLPGLSPAGPELG 939
PA P A Q GLP +GP LG
Sbjct: 2727 PAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILG 2762
Score = 31.6 bits (70), Expect = 4.0
Identities = 72/303 (23%), Positives = 96/303 (31%), Gaps = 34/303 (11%)
Query: 693 AAVPGMNTLG--PSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGS-Q 749
A VP + G P+ PR FP A P P + P G R A PG
Sbjct: 2169 AQVPSQDPFGLAPAYPLEPR-FPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFH 2227
Query: 750 NMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQ 809
P + S + P N +P VG + G S +
Sbjct: 2228 TTPPGTPRHQPSTPDPFLKPRCPSLDN--LAVPESPGVGGGKASEPLLSPPPFGESRKAL 2285
Query: 810 QHNK---GTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNL--SGQTPGNSNVSPFTAAS 864
+ K G +P P + V G + P++ + TP S V P +
Sbjct: 2286 EVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGL 2345
Query: 865 SFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPP--- 921
Q+ P P+ P P GS P + T P P PPP
Sbjct: 2346 GLRPQEP-------PPAQALAPSPPSHP--DIFRPGSYTDPYAQPPLT--PRPQPPPPES 2394
Query: 922 --TAPQQGLP----GLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELPFAYS 975
P + LP PA P+ + SQSP + A C PV T + P YS
Sbjct: 2395 CCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS--PV-TPRFQSPDPYS 2451
Query: 976 GQP 978
P
Sbjct: 2452 RPP 2454
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 69.7 bits (169), Expect = 1e-11
Identities = 137/582 (23%), Positives = 202/582 (34%), Gaps = 104/582 (17%)
Query: 397 HQLQQIAAKQKREQMLQN---PQQATPAP--APGQMSTWQQTGPSHSSLDVPYPMEKPA- 450
H+LQQ ++R + PQQ+ P+P AP T Q + P P P +P
Sbjct: 1819 HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQ-----TPQPPAQPQP 1873
Query: 451 SPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLN-----QNSANN 505
SP S S P S+ +P P + PP+ + + A
Sbjct: 1874 SPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPP---AQPPPAAVEAARQIEREAQQ 1930
Query: 506 QGSV--LDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPK 563
Q + ++ N+ P G G+PGS + +L P Q+S
Sbjct: 1931 QQHLYRVNINNSMPPGR----TGMGTPGSQMAPVSLNVPRPNQVSG-------------- 1972
Query: 564 PGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSV-ASSHNSSPYLSSQQQAAVMK 622
P +PPGQ Q P+ Q G P +S+ A + + P + S Q +
Sbjct: 1973 ----PVMPSMPPGQWQQ---APLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSIS 2025
Query: 623 QHQL--LLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGS 680
L LL K Q+ Q L+ L+A KQ+ +++ P P S
Sbjct: 2026 PSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQS 2085
Query: 681 FPQQVGQFTGSSAAVPGMNTLGPSNSSCPR------------VFPQAGNLMPMGPGH--- 725
P Q P + L + PR + PQ L M PGH
Sbjct: 2086 QPGMQPQ--PGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPN 2143
Query: 726 -ASVSS-----LPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHA 779
AS++ L QQ + Q Q Q GMA G+ PQ G+
Sbjct: 2144 MASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYP 2203
Query: 780 -----------HIPRQ-TNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPR 827
H+P Q +++GQ ++A GQ LG G PGL P
Sbjct: 2204 PAMQQQQRMQQHLPLQGSSMGQ---MAAQMGQ--LGQMG----------QPGLGADSTPN 2248
Query: 828 VSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPN 887
+ A+ Q Q Q M G +PG N P + Q + Q + ++ N
Sbjct: 2249 IQQAL--QQRILQQQQMKQQIG-SPGQPN--PMSPQQHMLSGQPQASHLPGQQIATSLSN 2303
Query: 888 RPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLP 929
+ +P + PP S+ P P+P +PQ G P
Sbjct: 2304 QVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2345
Score = 61.2 bits (147), Expect = 5e-09
Identities = 137/572 (23%), Positives = 211/572 (36%), Gaps = 140/572 (24%)
Query: 324 QTFLGPSSAPVSTDSPSLGGSQTLFHTSG-QPRADNPSPNLMPASAQAQNAQRALAGVVL 382
Q+ P+SAP T + QT + QP + SP P+ A+ Q G
Sbjct: 1842 QSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1901
Query: 383 --------PSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTG 434
P+Q P A E +A Q+++ A+Q++ N + P G + Q
Sbjct: 1902 SQVPAPPPPAQPPPAAVE--AARQIER-EAQQQQHLYRVNINNSMPPGRTGMGTPGSQMA 1958
Query: 435 PSHSSLDVPYPME-----KPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHV-- 487
P SL+VP P + P+ P Q + MP + PRP + V
Sbjct: 1959 PV--SLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGL----PRPVISMQAQAAVAG 2012
Query: 488 -NLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYL--- 543
+ S QPP +++ ++ + L SP S Q + ++ L
Sbjct: 2013 PRMPSVQPPRSISPSALQDLLRTLK-----------------SPSSPQQQQQVLNILKSN 2055
Query: 544 PQQLSHISHEQNSLFL-----MKPKPGNMPFRSLVP-PGQEQNPS--------------S 583
PQ ++ ++ + ++ M+P+PG + P PG Q PS
Sbjct: 2056 PQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPG 2115
Query: 584 VPVQAQATS-VGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQ 642
VP Q QA + Q A+++ + ++ S Q M + QLL QQ+Q++QQQ+ Q
Sbjct: 2116 VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQ 2175
Query: 643 QQ--------------QFLQRQ---QHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQV 685
QQ QF Q Q + A Q++Q+ Q+HL P QGS +
Sbjct: 2176 QQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHL---------PLQGS---SM 2223
Query: 686 GQFTGSSAAVPGMNTLGPSNSSCPRV-----------------FPQAGNLMPMGP----- 723
GQ + M G S P + G PM P
Sbjct: 2224 GQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHML 2283
Query: 724 -GHASVSSLP-----TNSGQQDRGVA--QFPGSQNMPQSSLYGMASGITQIVAQPPPQAT 775
G S LP T+ Q R A Q P Q+ P S S +I QP P
Sbjct: 2284 SGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS-----SPSPRIQPQPSPH-- 2336
Query: 776 NGHAHIPRQT---NVGQNTSVSAAYGQNSLGS 804
H+ QT + G +++++ Q LG+
Sbjct: 2337 ----HVSPQTGSPHPGLAVTMASSIDQGHLGN 2364
Score = 47.8 bits (112), Expect = 5e-05
Identities = 143/623 (22%), Positives = 224/623 (35%), Gaps = 146/623 (23%)
Query: 402 IAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPY------------PMEKP 449
+ Q+ L NP P S+ Q+ ++++L +PY P ++P
Sbjct: 422 VGTGQQNATSLSNPNPIDP-------SSMQR---AYAALGLPYMNQPQTQLQPQVPGQQP 471
Query: 450 ASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQP-PSNLNQ-NSANNQG 507
A P +++Q T + L N + GG NL+S P++L N N G
Sbjct: 472 AQPQTHQQMRTLNPL----GNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDG 527
Query: 508 SVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQL-SHISHEQNSLFLMKPKPGN 566
S + GN LS P S + ++ Q L SH+ H+ P P
Sbjct: 528 S--NSGNIGTLSTIPT---AAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAA 582
Query: 567 MPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQL 626
+ R + +N + A A V + A+S + +L +++ + K+ +
Sbjct: 583 LKDRRM------EN-----LVAYAKKV--EGDMYESANSRDEYYHLLAEKIYKIQKELE- 628
Query: 627 LLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPP--PQYQD--PTQGSFP 682
E+++ L +Q L Q L A +PP PQ Q P G
Sbjct: 629 --------EKRRSRLHKQGILGNQPALPAPG---------AQPPVIPQAQPVRPPNGPLS 671
Query: 683 QQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGV 742
V + S GMN+ P + ++ PQA PMGP AS P N Q +
Sbjct: 672 LPVNRMQVSQ----GMNSFNPMSLGNVQL-PQA----PMGPRAAS----PMNHSVQMNSM 718
Query: 743 AQFPGS----QNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYG 798
PG MPQ M + ++AQ P Q+ +P+ + ++S G
Sbjct: 719 GSVPGMAISPSRMPQPPNM-MGAHTNNMMAQAPAQSQ----FLPQNQFPSSSGAMSVGMG 773
Query: 799 QNSLGSSGLSQQHNKGT--------LNPGLTKPPVPRV--SPAMGGQNSSWQHQGMPNLS 848
Q +G+SQ G L P ++ P P V SP + GMP+L
Sbjct: 774 QPP-AQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQ 832
Query: 849 GQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSA 908
TP M+ PQ A P +P P+SS+
Sbjct: 833 HTTPPG---------------------MTPPQ--PAAPTQPSTPVSSSG----------- 858
Query: 909 QQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQ 968
+T P P P+A Q + + P + A +Q+ + + A P + Q
Sbjct: 859 --QTPTPTPGSVPSATQ------TQSTPTVQAAAQAQVTPQPQTPVQPPSVATP--QSSQ 908
Query: 969 ELPFAYSGQPGGSGLSSVAGHTD 991
+ P QP G+ LS A D
Sbjct: 909 QQPTPVHAQPPGTPLSQAAASID 931
Score = 41.2 bits (95), Expect = 0.005
Identities = 90/366 (24%), Positives = 121/366 (33%), Gaps = 98/366 (26%)
Query: 630 QQKQREQQQKH-LQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQF 688
+ K R+QQ +H LQQ Q ++R+ + TR PQ P+ S P
Sbjct: 1809 KHKLRQQQIQHRLQQAQLMRRRMATMN-----------TRNVPQQSLPSPTSAP------ 1851
Query: 689 TGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGS 748
PG T PS P+ P P + VS P R S
Sbjct: 1852 -------PGTPTQQPSTPQTPQP--------PAQPQPSPVSMSPAGFPSVARTQPPTTVS 1896
Query: 749 QNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQ-----NTSVSAAYGQNSLG 803
P S + AQPPP A I R+ Q N + S G+ +G
Sbjct: 1897 TGKPTSQVPAPPPP-----AQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMG 1951
Query: 804 SSGLSQQHNKGTLN---PGLTKPPV-PRVSPAMGGQNSSWQHQGMPNL------------ 847
+ G Q +LN P PV P + P Q Q Q MP L
Sbjct: 1952 TPG--SQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAA 2009
Query: 848 -------SGQTPGNSNVSPF--------TAASSFHMQQQAHLKMSSPQFSQA-------- 884
S Q P + + S + +S QQ ++ S+PQ A
Sbjct: 2010 VAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK 2069
Query: 885 -VPNRP-MAPMSSAAAVGSLLPPVSAQQRTS----------APAPAPPPTAPQQGLPGLS 932
V N+P M P + + P Q+ S P P PP QQ + GL+
Sbjct: 2070 YVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ--QQAMGGLN 2127
Query: 933 PAGPEL 938
P G L
Sbjct: 2128 PQGQAL 2133
Score = 34.7 bits (78), Expect = 0.47
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 867 HMQQQAHL--KMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAP 924
H QQA L + + ++ VP + + +SA PP + Q+ S P PP P
Sbjct: 1819 HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA-------PPGTPTQQPSTPQTPQPPAQP 1871
Query: 925 QQGLPGLSPAGPELGAFSQSPASQMGGR 952
Q +SPAG A +Q P + G+
Sbjct: 1872 QPSPVSMSPAGFPSVARTQPPTTVSTGK 1899
Score = 30.4 bits (67), Expect = 8.8
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 4/105 (3%)
Query: 799 QNSLGSSGLSQQHNKGTLNPGLTKP-PVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNV 857
QN++GS G QQ+ NP P + R A+G + +Q L Q PG
Sbjct: 416 QNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALG---LPYMNQPQTQLQPQVPGQQPA 472
Query: 858 SPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSL 902
P T + + M+ P +P +S +A SL
Sbjct: 473 QPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSL 517
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 69.7 bits (169), Expect = 1e-11
Identities = 137/582 (23%), Positives = 202/582 (34%), Gaps = 104/582 (17%)
Query: 397 HQLQQIAAKQKREQMLQN---PQQATPAP--APGQMSTWQQTGPSHSSLDVPYPMEKPA- 450
H+LQQ ++R + PQQ+ P+P AP T Q + P P P +P
Sbjct: 1857 HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQ-----TPQPPAQPQP 1911
Query: 451 SPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLN-----QNSANN 505
SP S S P S+ +P P + PP+ + + A
Sbjct: 1912 SPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPP---AQPPPAAVEAARQIEREAQQ 1968
Query: 506 QGSV--LDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPK 563
Q + ++ N+ P G G+PGS + +L P Q+S
Sbjct: 1969 QQHLYRVNINNSMPPGR----TGMGTPGSQMAPVSLNVPRPNQVSG-------------- 2010
Query: 564 PGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSV-ASSHNSSPYLSSQQQAAVMK 622
P +PPGQ Q P+ Q G P +S+ A + + P + S Q +
Sbjct: 2011 ----PVMPSMPPGQWQQ---APLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSIS 2063
Query: 623 QHQL--LLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGS 680
L LL K Q+ Q L+ L+A KQ+ +++ P P S
Sbjct: 2064 PSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQS 2123
Query: 681 FPQQVGQFTGSSAAVPGMNTLGPSNSSCPR------------VFPQAGNLMPMGPGH--- 725
P Q P + L + PR + PQ L M PGH
Sbjct: 2124 QPGMQPQ--PGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPN 2181
Query: 726 -ASVSS-----LPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHA 779
AS++ L QQ + Q Q Q GMA G+ PQ G+
Sbjct: 2182 MASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYP 2241
Query: 780 -----------HIPRQ-TNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPR 827
H+P Q +++GQ ++A GQ LG G PGL P
Sbjct: 2242 PAMQQQQRMQQHLPLQGSSMGQ---MAAQMGQ--LGQMG----------QPGLGADSTPN 2286
Query: 828 VSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPN 887
+ A+ Q Q Q M G +PG N P + Q + Q + ++ N
Sbjct: 2287 IQQAL--QQRILQQQQMKQQIG-SPGQPN--PMSPQQHMLSGQPQASHLPGQQIATSLSN 2341
Query: 888 RPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLP 929
+ +P + PP S+ P P+P +PQ G P
Sbjct: 2342 QVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2383
Score = 61.2 bits (147), Expect = 5e-09
Identities = 137/572 (23%), Positives = 211/572 (36%), Gaps = 140/572 (24%)
Query: 324 QTFLGPSSAPVSTDSPSLGGSQTLFHTSG-QPRADNPSPNLMPASAQAQNAQRALAGVVL 382
Q+ P+SAP T + QT + QP + SP P+ A+ Q G
Sbjct: 1880 QSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPT 1939
Query: 383 --------PSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTG 434
P+Q P A E +A Q+++ A+Q++ N + P G + Q
Sbjct: 1940 SQVPAPPPPAQPPPAAVE--AARQIER-EAQQQQHLYRVNINNSMPPGRTGMGTPGSQMA 1996
Query: 435 PSHSSLDVPYPME-----KPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHV-- 487
P SL+VP P + P+ P Q + MP + PRP + V
Sbjct: 1997 PV--SLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGL----PRPVISMQAQAAVAG 2050
Query: 488 -NLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYL--- 543
+ S QPP +++ ++ + L SP S Q + ++ L
Sbjct: 2051 PRMPSVQPPRSISPSALQDLLRTLK-----------------SPSSPQQQQQVLNILKSN 2093
Query: 544 PQQLSHISHEQNSLFL-----MKPKPGNMPFRSLVP-PGQEQNPS--------------S 583
PQ ++ ++ + ++ M+P+PG + P PG Q PS
Sbjct: 2094 PQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPG 2153
Query: 584 VPVQAQATS-VGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQ 642
VP Q QA + Q A+++ + ++ S Q M + QLL QQ+Q++QQQ+ Q
Sbjct: 2154 VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQ 2213
Query: 643 QQ--------------QFLQRQ---QHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQV 685
QQ QF Q Q + A Q++Q+ Q+HL P QGS +
Sbjct: 2214 QQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHL---------PLQGS---SM 2261
Query: 686 GQFTGSSAAVPGMNTLGPSNSSCPRV-----------------FPQAGNLMPMGP----- 723
GQ + M G S P + G PM P
Sbjct: 2262 GQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHML 2321
Query: 724 -GHASVSSLP-----TNSGQQDRGVA--QFPGSQNMPQSSLYGMASGITQIVAQPPPQAT 775
G S LP T+ Q R A Q P Q+ P S S +I QP P
Sbjct: 2322 SGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS-----SPSPRIQPQPSPH-- 2374
Query: 776 NGHAHIPRQT---NVGQNTSVSAAYGQNSLGS 804
H+ QT + G +++++ Q LG+
Sbjct: 2375 ----HVSPQTGSPHPGLAVTMASSIDQGHLGN 2402
Score = 47.8 bits (112), Expect = 5e-05
Identities = 143/623 (22%), Positives = 224/623 (35%), Gaps = 146/623 (23%)
Query: 402 IAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPY------------PMEKP 449
+ Q+ L NP P S+ Q+ ++++L +PY P ++P
Sbjct: 460 VGTGQQNATSLSNPNPIDP-------SSMQR---AYAALGLPYMNQPQTQLQPQVPGQQP 509
Query: 450 ASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQP-PSNLNQ-NSANNQG 507
A P +++Q T + L N + GG NL+S P++L N N G
Sbjct: 510 AQPQTHQQMRTLNPL----GNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDG 565
Query: 508 SVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQL-SHISHEQNSLFLMKPKPGN 566
S + GN LS P S + ++ Q L SH+ H+ P P
Sbjct: 566 S--NSGNIGTLSTIPT---AAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAA 620
Query: 567 MPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQL 626
+ R + +N + A A V + A+S + +L +++ + K+ +
Sbjct: 621 LKDRRM------EN-----LVAYAKKV--EGDMYESANSRDEYYHLLAEKIYKIQKELE- 666
Query: 627 LLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPP--PQYQD--PTQGSFP 682
E+++ L +Q L Q L A +PP PQ Q P G
Sbjct: 667 --------EKRRSRLHKQGILGNQPALPAPG---------AQPPVIPQAQPVRPPNGPLS 709
Query: 683 QQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGV 742
V + S GMN+ P + ++ PQA PMGP AS P N Q +
Sbjct: 710 LPVNRMQVSQ----GMNSFNPMSLGNVQL-PQA----PMGPRAAS----PMNHSVQMNSM 756
Query: 743 AQFPGS----QNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYG 798
PG MPQ M + ++AQ P Q+ +P+ + ++S G
Sbjct: 757 GSVPGMAISPSRMPQPPNM-MGAHTNNMMAQAPAQSQ----FLPQNQFPSSSGAMSVGMG 811
Query: 799 QNSLGSSGLSQQHNKGT--------LNPGLTKPPVPRV--SPAMGGQNSSWQHQGMPNLS 848
Q +G+SQ G L P ++ P P V SP + GMP+L
Sbjct: 812 QPP-AQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQ 870
Query: 849 GQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSA 908
TP M+ PQ A P +P P+SS+
Sbjct: 871 HTTPPG---------------------MTPPQ--PAAPTQPSTPVSSSG----------- 896
Query: 909 QQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQ 968
+T P P P+A Q + + P + A +Q+ + + A P + Q
Sbjct: 897 --QTPTPTPGSVPSATQ------TQSTPTVQAAAQAQVTPQPQTPVQPPSVATP--QSSQ 946
Query: 969 ELPFAYSGQPGGSGLSSVAGHTD 991
+ P QP G+ LS A D
Sbjct: 947 QQPTPVHAQPPGTPLSQAAASID 969
Score = 41.2 bits (95), Expect = 0.005
Identities = 90/366 (24%), Positives = 121/366 (33%), Gaps = 98/366 (26%)
Query: 630 QQKQREQQQKH-LQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQF 688
+ K R+QQ +H LQQ Q ++R+ + TR PQ P+ S P
Sbjct: 1847 KHKLRQQQIQHRLQQAQLMRRRMATMN-----------TRNVPQQSLPSPTSAP------ 1889
Query: 689 TGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGS 748
PG T PS P+ P P + VS P R S
Sbjct: 1890 -------PGTPTQQPSTPQTPQP--------PAQPQPSPVSMSPAGFPSVARTQPPTTVS 1934
Query: 749 QNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQ-----NTSVSAAYGQNSLG 803
P S + AQPPP A I R+ Q N + S G+ +G
Sbjct: 1935 TGKPTSQVPAPPPP-----AQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMG 1989
Query: 804 SSGLSQQHNKGTLN---PGLTKPPV-PRVSPAMGGQNSSWQHQGMPNL------------ 847
+ G Q +LN P PV P + P Q Q Q MP L
Sbjct: 1990 TPG--SQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAA 2047
Query: 848 -------SGQTPGNSNVSPF--------TAASSFHMQQQAHLKMSSPQFSQA-------- 884
S Q P + + S + +S QQ ++ S+PQ A
Sbjct: 2048 VAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAK 2107
Query: 885 -VPNRP-MAPMSSAAAVGSLLPPVSAQQRTS----------APAPAPPPTAPQQGLPGLS 932
V N+P M P + + P Q+ S P P PP QQ + GL+
Sbjct: 2108 YVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ--QQAMGGLN 2165
Query: 933 PAGPEL 938
P G L
Sbjct: 2166 PQGQAL 2171
Score = 34.7 bits (78), Expect = 0.47
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 9/88 (10%)
Query: 867 HMQQQAHL--KMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAP 924
H QQA L + + ++ VP + + +SA PP + Q+ S P PP P
Sbjct: 1857 HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA-------PPGTPTQQPSTPQTPQPPAQP 1909
Query: 925 QQGLPGLSPAGPELGAFSQSPASQMGGR 952
Q +SPAG A +Q P + G+
Sbjct: 1910 QPSPVSMSPAGFPSVARTQPPTTVSTGK 1937
Score = 30.4 bits (67), Expect = 8.8
Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 4/105 (3%)
Query: 799 QNSLGSSGLSQQHNKGTLNPGLTKP-PVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNV 857
QN++GS G QQ+ NP P + R A+G + +Q L Q PG
Sbjct: 454 QNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALG---LPYMNQPQTQLQPQVPGQQPA 510
Query: 858 SPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSL 902
P T + + M+ P +P +S +A SL
Sbjct: 511 QPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSL 555
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 69.3 bits (168), Expect = 2e-11
Identities = 113/454 (24%), Positives = 168/454 (37%), Gaps = 72/454 (15%)
Query: 528 GSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVP-PGQEQNPSSVPV 586
G G+G S + I N +M P GN+ + P P E P +
Sbjct: 151 GPMGAGNSVRMEAGFPMASGPGIIRMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRP 210
Query: 587 QAQATSVGT----------QPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQ 636
+Q+ ++ P+ S+A H+ +S +Q QL QQ+Q++Q
Sbjct: 211 ASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQ-QQQQQQQQ 269
Query: 637 QQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVP 696
QQ+ QQQQ Q+QQ L A +Q Q+ PQ+ PTQ P P
Sbjct: 270 QQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVP-------------P 316
Query: 697 GMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSL 756
G N L +G L P P S+ ++ N G + A PG +
Sbjct: 317 GWNQL------------PSGALQP-PPAQGSLGTMTANQGWKK---APLPGPMQQQLQAR 360
Query: 757 YGMASGITQIVAQPPP-------QATNGHAHIPRQTNVGQNTS--VSAAYGQNSLGSSGL 807
+A+ Q + PPP QA+ H + P+ +N GQ T+ + + G S + L
Sbjct: 361 PSLAT--VQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPL 418
Query: 808 SQQH--NKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTP-GNSNVSPFTAAS 864
Q H NK +P + + SPA + Q Q P P P ++
Sbjct: 419 QQPHLTNK---SPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPG 475
Query: 865 SFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSL---LPP-VSAQQRTSAPAPAPP 920
M QQ ++ + Q PN+ P S +G + LPP SA Q
Sbjct: 476 RNPMVQQGNVPPNFMVMQQQPPNQ--GPQSLHPGLGGMPKRLPPGFSAGQAN-------- 525
Query: 921 PTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAG 954
P Q +P + P Q A+Q AG
Sbjct: 526 PNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAG 559
Score = 60.5 bits (145), Expect = 8e-09
Identities = 195/915 (21%), Positives = 301/915 (32%), Gaps = 167/915 (18%)
Query: 141 RREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNG 200
R P V I G +S + P S +D L S LH+
Sbjct: 175 RMNNPATVMIPPGGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLL------SGLHIQQ 228
Query: 201 GSNPSESF--------PLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWK 252
S+PS S P+S+N+++ L Q +Q+ +
Sbjct: 229 QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQ--------QQQQQQQQQQQQQQQQQ 280
Query: 253 ELIEELNRSVPDED-------MKDLFNEDFEEKKDP---ESSGSATQTPLAQDINIKTEF 302
+ ++L P + ++ F + P + A Q P AQ ++ T
Sbjct: 281 QQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQG-SLGTMT 339
Query: 303 SPAAFEQEQLGSP---QVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNP 359
+ +++ L P Q++A + T PS P S SQ HT+ P+ NP
Sbjct: 340 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQA--HTNF-PQMSNP 396
Query: 360 SPNLMPASAQAQNAQRALAGVVLPSQGPG--GASELSSAHQLQQIA------AKQKREQM 411
P Q ++ Q + V P Q P S SS QQ + Q ++QM
Sbjct: 397 GQFTAP---QMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQM 453
Query: 412 LQNPQQATPAP--------APGQMSTWQQTG--PSHSSLDVPYPMEKPAS---------- 451
P Q P P +PG+ QQ P+ + P + P S
Sbjct: 454 GPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPK 513
Query: 452 --PSSYKQDFTNSKLLM--MPSVNKSSP-RPGGPYLQ---------------PSHVNLLS 491
P + N + +PS ++P G P LQ P + +S
Sbjct: 514 RLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVS 573
Query: 492 HQPPSNLNQNSANNQGSVLDY-GNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQL--S 548
H PP+ + + G++ + T + QG P G P+ + + QQ+ S
Sbjct: 574 HGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGP--PSQLMGMHQQIVPS 631
Query: 549 HISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNS 608
Q L P + L+P GQ + V + ++G P ++
Sbjct: 632 QGQMVQQQGTLNPQNPMILSRAQLMPQGQ------MMVNPPSQNLGPSPQRMTPPKQ--- 682
Query: 609 SPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTR 668
+ SQQ +M H ++ Q Q QQ + +Q + Q + Q +
Sbjct: 683 ---MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG 739
Query: 669 PPPQYQDPT---QGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLM-PMGPG 724
P + PT QG+ Q GQ +G + GP N+S +V G ++ P GP
Sbjct: 740 PAQIMRGPTPNMQGNMVQFTGQMSGQM-----LPQQGPVNNSPSQVMGIQGQVLRPPGPS 794
Query: 725 H--ASVSSLPTNSGQQDRGVAQF-------------PGSQNMPQSSLYGMA-SGITQIVA 768
A P + D ++Q P Q M +S G SG
Sbjct: 795 PHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFN 854
Query: 769 QPPPQATNGHAHIPRQTNVGQNTS--------------VSAAYGQNSLGSSGLSQQHNKG 814
P A NG+ Q + GQN V+ S G G++ + N
Sbjct: 855 APFSGAPNGN-----QMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNT 909
Query: 815 TLN-PGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAH 873
N P KPP + +S Q P+ ++ P ++
Sbjct: 910 NANKPKKKKPPRKK--------KNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGP 961
Query: 874 LKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSP 933
P+FS P P P+ +PP Q AP P PP PQ LP
Sbjct: 962 ---KLPEFSNRPPGYPSQPVEQRPL--QQMPPQLMQH--VAPPPQPPQQQPQPQLPQQQQ 1014
Query: 934 AGPELGAFSQSPASQ 948
P SQ Q
Sbjct: 1015 PPPPSQPQSQQQQQQ 1029
Score = 58.5 bits (140), Expect = 3e-08
Identities = 188/860 (21%), Positives = 279/860 (32%), Gaps = 184/860 (21%)
Query: 233 GSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKD--LFNEDFEEKKDPESSGSATQT 290
G++S S + P N EL R D D L +++ P S +
Sbjct: 188 GNVSSSMMAPGPN------PELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHH 241
Query: 291 PLAQDINIKTEFSPAAF-------------------EQEQLGSPQVRAGSAGQ------- 324
P+ Q +++ + +PA F +Q+Q Q++A Q
Sbjct: 242 PM-QPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQ 300
Query: 325 ----TFLGPSSAPVSTD-----------SPSLGGSQTLFHTSGQPRADNPSPNLMPASAQ 369
F P+ PV P+ G T+ G +A P P Q
Sbjct: 301 GIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGP-----MQQ 355
Query: 370 AQNAQRALAGVVLPSQGPG----GASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPG 425
A+ +LA V PS P G+ + S AH + NP Q T AP
Sbjct: 356 QLQARPSLATVQTPSHPPPPYPFGSQQASQAHT---------NFPQMSNPGQFT---APQ 403
Query: 426 QMSTWQQTGPSHSSLDVPYPMEKP----ASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPY 481
S Q GPS VP P+++P SP+S F P+VN++ + G
Sbjct: 404 MKSL--QGGPSR----VPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRP 457
Query: 482 LQPSHVNLLSHQPPSNLNQNSANNQGSV--------LDYGNTKPLSHYKA---------- 523
Q + + QP S+ +N QG+V N P S +
Sbjct: 458 PQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRLPP 517
Query: 524 --DCGQGSPGSGQSK-PALMAYLP-----QQLSHISHEQNSLFLMKPKPGNMPFRSLVPP 575
GQ +P Q + P+ A P QL + Q++ P N S PP
Sbjct: 518 GFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPP 577
Query: 576 GQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQRE 635
Q PS + + + V + N + +M HQ ++ Q Q
Sbjct: 578 NMMQ-PSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMV 636
Query: 636 QQQKHL--QQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSA 693
QQQ L Q L R Q + Q P PQ P P+Q+ G
Sbjct: 637 QQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTP-----PKQMLSQQGPQM 691
Query: 694 AVPGMNTLGPSNSSCPRVFPQAGNLMP-----------------MGPGHASVSSLPTNSG 736
P +GP + P +M + PG A + PT +
Sbjct: 692 MAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNM 751
Query: 737 QQDRGVAQFPGS-------QNMPQSSLYGMASGITQIVAQPP-PQATNGHAHIPRQTNVG 788
Q + + QF G Q P ++ GI V +PP P H T
Sbjct: 752 QGN--MVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTAN 809
Query: 789 QNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLS 848
+ S+S S+ QQ N VP AM G ++S H S
Sbjct: 810 NDVSLSQMMPDVSI------QQTNM-----------VPPHVQAMQGNSASGNH-----FS 847
Query: 849 GQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSA 908
G G S +PF+ A + + +MS Q + P ++S V L +SA
Sbjct: 848 GH--GMSFNAPFSGAPNGN-------QMSCGQ-NPGFPVNKDVTLTSPLLVNLLQSDISA 897
Query: 909 --------QQRTSA--PAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCT 958
Q T+A P PP + L+ ++ + G G++
Sbjct: 898 GHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLD 957
Query: 959 QAYPVRTAGQELPFAYSGQP 978
+ P P Y QP
Sbjct: 958 NSGPKLPEFSNRPPGYPSQP 977
Score = 50.1 bits (118), Expect = 1e-05
Identities = 151/682 (22%), Positives = 234/682 (34%), Gaps = 137/682 (20%)
Query: 352 GQPRADNPSPNLMPASAQAQNAQRALAG----VVLPSQ---GPGGASELSSAHQLQQIAA 404
GQ + PS NL P+ + ++ L+ ++ P GP G L ++QI
Sbjct: 659 GQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMT 718
Query: 405 KQ----KREQMLQNPQQATPAPAP-----------------GQMSTWQ--QTGPSHSS-- 439
Q K++ QN P PA GQMS Q GP ++S
Sbjct: 719 NQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPS 778
Query: 440 --LDVPYPMEKPASPSSY------------KQDFTNSKLLMMPSVNKSSPRPGGPYLQPS 485
+ + + +P PS + D + S+ MMP V+ P++Q
Sbjct: 779 QVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQ--MMPDVSIQQTNMVPPHVQAM 836
Query: 486 HVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSK------PAL 539
N S S S N S GN + CGQ +PG +K P L
Sbjct: 837 QGNSASGNHFSGHGM-SFNAPFSGAPNGN-------QMSCGQ-NPGFPVNKDVTLTSPLL 887
Query: 540 MAYLPQQLSH----ISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGT 595
+ L +S ++++QN+ KPK P + P + P +
Sbjct: 888 VNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEAD--- 944
Query: 596 QPP-----AVSVASSHNSSPYLSS---------------QQQAAVMKQHQLLLDQQKQRE 635
QPP +++ +S P S+ QQ + QH Q Q++
Sbjct: 945 QPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQ 1004
Query: 636 QQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAV 695
Q + QQQQ Q Q++QQ Q+ + QDP P S
Sbjct: 1005 PQPQLPQQQQPPPPSQP--QSQQQQQQQQQMMMMLMMQQDPKSVRLPV-------SQNVH 1055
Query: 696 PGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLP----------TNSGQQDRGVAQF 745
P L P + P + +M G ASV P T G R +
Sbjct: 1056 PPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQ 1115
Query: 746 PGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSS 805
QN S L MAS + + P G ++P + QN + G S
Sbjct: 1116 ESPQNPSSSPLAEMAS-LPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTG---PKPGPS 1171
Query: 806 GLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASS 865
LS T+ P+ P +S H PN++ T + +P A+
Sbjct: 1172 PLS-----------ATQGATPQQPPVNSLPSSHGHH--FPNVAAPTQTSRPKTPNRASPR 1218
Query: 866 FHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQ 925
+ Q + + S + S+ ++P A++ L PP + + P P P
Sbjct: 1219 PYYPQTPNNRPPSTEPSEI----SLSPERLNASIAGLFPP-----QINIPLPPRPNLNRG 1269
Query: 926 QGLPGLSPAGPELGAFSQSPAS 947
GL+P L A Q+P++
Sbjct: 1270 FDQQGLNPT--TLKAIGQAPSN 1289
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 67.0 bits (162), Expect = 9e-11
Identities = 148/645 (22%), Positives = 210/645 (32%), Gaps = 135/645 (20%)
Query: 372 NAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP-------APAP 424
++ R G ++ G GGA+ LS A Q+ Q+P ATP +P+P
Sbjct: 311 SSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSP 370
Query: 425 GQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRP-GGPYLQ 483
M ++ + P +SS P P P+ P S + + + G Y
Sbjct: 371 -MMRSYGGSYPEYSSPSAPPP--PPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA 427
Query: 484 PSHVNLLSHQ------PPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKP 537
S + Q P +QGS +D K Y G GS Q
Sbjct: 428 ASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLY----GMGSNPHSQ--- 480
Query: 538 ALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQP 597
PQQ S P PG S PPG ++ P + + G Q
Sbjct: 481 ------PQQSS-------------PYPGG----SYGPPGPQRYPIGIQGRTPGAMAGMQY 517
Query: 598 P------------------------AVSVASSHNSSPYLSSQQQAAVMK-QHQLLLDQQK 632
P VS PY S Q Q + Q Q L Q +
Sbjct: 518 PQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQ 577
Query: 633 QREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQF---- 688
QR Q Q+ + Q+ + R Q LA + +L Q S P G
Sbjct: 578 QRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLI------QQERPSSLPDLSGSIDDLP 631
Query: 689 TGSSAAVPGMNTLGPSNSS------------CPRVFPQAGNLMPMGPGHASVSSLPTNSG 736
TG+ A + + S SS P P ++ P GP + V S P S
Sbjct: 632 TGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI-PGGPSPSPVGS-PVGSN 689
Query: 737 QQDRGV---AQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHA-----------HIP 782
Q G A PGSQ PQ S ++Q P G + P
Sbjct: 690 QSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP 749
Query: 783 RQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQ 842
+QT + S GQ G S Q ++ GT P +++ G + +
Sbjct: 750 QQTGPSMSPHPSPG-GQMHAGISSFQQSNSSGTYGPQMSQ------YGPQGNYSRPPAYS 802
Query: 843 GMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSL 902
G+P+ S PG M A+ +M SQ P+ M SA
Sbjct: 803 GVPSASYSGPGPG------------MGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRP 850
Query: 903 LPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPAS 947
P + S+P + QQG PG+ P P + +Q A+
Sbjct: 851 FPGNMSSMTPSSPGMS------QQGGPGMGPPMPTVNRKAQEAAA 889
Score = 57.0 bits (136), Expect = 9e-08
Identities = 177/829 (21%), Positives = 280/829 (33%), Gaps = 164/829 (19%)
Query: 276 EEKKDPESSGSATQTPLA------QDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGP 329
++ E G+ +Q PLA +D+N+ + P++ + G+
Sbjct: 583 QQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAV 642
Query: 330 S-SAPVSTDSPSLGGSQTLF------HTSGQPRADNPSPNLMPASAQAQNA----QRALA 378
S S S+ +Q+ F H S P +PSP P + + ++
Sbjct: 643 SASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIP 702
Query: 379 GVVLPSQGPGGASELSSAHQLQQIAAKQKREQML---QNPQQATPAPAPGQMSTWQQTGP 435
G +P Q PG SE SS L Q Q+R M +NPQ A P QQTGP
Sbjct: 703 GSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGP--------QQTGP 754
Query: 436 SHSSLDVPYPM---EKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQP---SHVNL 489
S S P+P + A SS++Q +NS P +++ P+ G Y +P S V
Sbjct: 755 SMS----PHPSPGGQMHAGISSFQQ--SNSSGTYGPQMSQYGPQ--GNYSRPPAYSGVPS 806
Query: 490 LSHQPPSNLNQNSANNQ---------------GSVLDYG-NTKPLSHYKADCGQGSPGSG 533
S+ P SANNQ G + G +P + SPG
Sbjct: 807 ASYSGPGPGMGISANNQMHGQGPSQPCGAVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMS 866
Query: 534 QSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQ-------NPSSVPV 586
Q M P + ++ + +M+ + R PG Q +P S P+
Sbjct: 867 QQGGPGMG-PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPM 925
Query: 587 QAQATSVGTQPPAVSVA----SSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQ 642
++ + TQ P S+A +S +S L+ K L K+ Q +
Sbjct: 926 NNSSSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESK 985
Query: 643 QQ---------QFLQRQQHLLAEQEKQQF-QRHLT----RPPPQYQDPTQGSFPQQVGQF 688
+ + + + L E E++ + R+LT R P P G P + +
Sbjct: 986 SKKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRL 1045
Query: 689 TGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGS 748
+ G+ + + + + + + +G ++ SSL Q
Sbjct: 1046 YVCVKEIGGLAQVNKN-----KKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIER 1100
Query: 749 QNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLS 808
P ++ Q QPP A +G S+ S GS+ ++
Sbjct: 1101 GEEPPPEVFSTGDTKKQPKLQPPSPANSG--------------SLQGPQTPQSTGSNSMA 1146
Query: 809 QQHNKGTLNPGLTKPPVP------RVSPAMGGQNSS------------------------ 838
+ PG KPP P +++P GG++S+
Sbjct: 1147 EV-------PGDLKPPTPASTPHGQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPN 1199
Query: 839 ---WQHQGMPNLSGQTPGNSNVSPF-----TAASSFHMQQQAHLKMSSPQF------SQA 884
Q MP++ G+ P N PF SS Q + SS Q S A
Sbjct: 1200 APYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGA 1259
Query: 885 VPNRPMAPMSS---AAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAF 941
+ N M A+ P Q P PP Q PGL P P +
Sbjct: 1260 MSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGGHQ--PGLYPQQPN---Y 1314
Query: 942 SQSPASQMGGRAGLHCTQAYPVRTAG--QELPFAYSGQPGGSGLSSVAG 988
+ G A H Y ++ + QE+ Y G G + G
Sbjct: 1315 KRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQG 1363
Score = 46.2 bits (108), Expect = 2e-04
Identities = 87/427 (20%), Positives = 134/427 (31%), Gaps = 68/427 (15%)
Query: 605 SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHL---------------QQQQFLQR 649
+H+ + + QQQ +Q Q QQ+Q++QQQ+H Q +++
Sbjct: 39 AHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQ 98
Query: 650 QQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLG------- 702
QH A+ Q PP + + P ++G+ G PG+ LG
Sbjct: 99 PQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVA 158
Query: 703 -PSNSSCPRVFPQAGNLMPM------GPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSS 755
P P P+ N GPG + + GQQ G+ G + ++
Sbjct: 159 VPGGGGGPAAVPEFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGM----GMMHSASAA 214
Query: 756 LYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNS-LGSSGLSQQHNKG 814
G + + + H P + G G G G G
Sbjct: 215 AAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAG 274
Query: 815 TLNPGLTKPPVPRVSPAMGGQN--------------SSWQHQGMPNLSGQTPGN----SN 856
G + A GG SS + QG + G G S
Sbjct: 275 GAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSK 334
Query: 857 VSPFTAASSFHM--QQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSA 914
+ +AA F Q H ++P +Q + + P + G P S+
Sbjct: 335 AAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTS----PSPMMRSYGGSYPEYSS------ 384
Query: 915 PAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQEL--PF 972
P+ PP P Q + AG G + +G G A P A Q+ P
Sbjct: 385 --PSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPA 442
Query: 973 AYSGQPG 979
G PG
Sbjct: 443 MSPGTPG 449
Score = 40.0 bits (92), Expect = 0.011
Identities = 85/349 (24%), Positives = 126/349 (36%), Gaps = 66/349 (18%)
Query: 680 SFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQD 739
S PQQ + G S PG P+ +P + PG + P QQD
Sbjct: 479 SQPQQSSPYPGGSYGPPG-----------PQRYPIG--IQGRTPGAMAGMQYPQ---QQD 522
Query: 740 RGVAQFPGSQNM--PQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAY 797
G A + + + PQ G+ SG Q QP H+P Q + S
Sbjct: 523 SGDATWKETFWLMPPQYGQQGV-SGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQ 581
Query: 798 GQNSLGSSGLSQQHNKGTLNPG--------LTKPPVPRVSPAMGGQ------------NS 837
Q + G + ++ L PG L + P P + G +S
Sbjct: 582 PQQDMSQEGYGTR-SQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSS 640
Query: 838 SWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMA-PMSSA 896
+ G + G N SPF+ +S H+ SP S N+ + P+S A
Sbjct: 641 AVSASGSTSSQGDQ-SNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPA 699
Query: 897 AAVGSLLPPV---SAQQRTSAPAPAPPPTAPQQGL-------PGLSPAGPELGAFSQSPA 946
+ GS +PP S + +S PA + P ++G P ++ GP+ S SP
Sbjct: 700 SIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPH 759
Query: 947 SQMGGR--AGLHC-TQAYPVRTAGQEL-----------PFAYSGQPGGS 981
GG+ AG+ Q+ T G ++ P AYSG P S
Sbjct: 760 PSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSAS 808
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 64.7 bits (156), Expect = 4e-10
Identities = 139/583 (23%), Positives = 203/583 (34%), Gaps = 79/583 (13%)
Query: 303 SPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQ-PRADNPSP 361
+P + G Q G T P P PS G Q GQ P + SP
Sbjct: 426 TPQRYPMTMQGRAQSAMGGLSYTQQIP---PYGQQGPSGYGQQ------GQTPYYNQQSP 476
Query: 362 NLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQ--QIAAKQK--REQMLQNPQQ 417
+ P Q +Q+ PSQ P Q Q Q+ + Q +Q Q P Q
Sbjct: 477 H--PQQQQPPYSQQP------PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQ 528
Query: 418 ATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRP 477
+PAP P Q ST QQ H PY +P + S Y+Q S + P+P
Sbjct: 529 QSPAPYPSQQSTTQQ----HPQSQPPY--SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQP 582
Query: 478 GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCG-QGSPGSGQSK 536
Q + + PP L+Q+S +Q S + + Q P S
Sbjct: 583 QSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDL 642
Query: 537 PALMAYLPQ----------QLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQE--QNPSSV 584
+ LP S IS Q + P PF P + PS
Sbjct: 643 SGSIDDLPMGTEGALSPGVSTSGISSSQGE----QSNPAQSPFSPHTSPHLPGIRGPSPS 698
Query: 585 PVQAQATSVGTQPPAVSVAS--SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQ 642
PV + A+ ++ +S A+ + P S Q ++M + R Q++ Q
Sbjct: 699 PVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ 758
Query: 643 QQQFLQRQQ-HLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQF--TGSSAAVPGMN 699
Q+ Q L+ ++ Q H YQ + GS+ Q GQ+ G P N
Sbjct: 759 MPQYSSPQPGSALSPRQPSGGQIHTGM--GSYQQNSMGSYGPQGGQYGPQGGYPRQPNYN 816
Query: 700 TLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGM 759
L N++ P AG + PMG +G Q G P +P +
Sbjct: 817 AL--PNANYPSA-GMAGGINPMG------------AGGQMHGQPGIPPYGTLPPGRMSHA 861
Query: 760 ASGITQI---VAQPPPQATNGHAHIPRQTN-VGQNTSVSAAYGQNSLGS--SGLSQQHNK 813
+ G +A PPQ +G P N Q T+V+ NS+ + G +
Sbjct: 862 SMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQG 921
Query: 814 GTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSN 856
G + G PP + +M G + QG P G T N++
Sbjct: 922 GMMGTG---PPYGQGINSMAGMINP---QGPPYSMGGTMANNS 958
Score = 50.8 bits (120), Expect = 6e-06
Identities = 155/697 (22%), Positives = 222/697 (31%), Gaps = 143/697 (20%)
Query: 320 GSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASA---QAQNAQRA 376
GS+ P SA + P+ G GQP +PS A+A Q Q++
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYG--------FGQPYGRSPSAVAAAAAAVFHQQHGGQQS 178
Query: 377 LAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQ-ATPAPAPGQMSTWQQTGP 435
L S G GG + Q + P + A P PAP + + G
Sbjct: 179 PGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGT 238
Query: 436 SHSSLDVPYPMEKP----ASPSSYKQDFTNSKLLMM------------------PSVNK- 472
S + P AS SS F + M P++N+
Sbjct: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL 298
Query: 473 ----SSPR-----PGGPYLQPSHVNLLSHQPPSNLNQ---NSANNQGSVLDYGNTKPLSH 520
SS R PGG Y P +Q +A + G + SH
Sbjct: 299 LTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSH 358
Query: 521 YKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQN 580
+ S G GQ +A PQ S + + M+P+P + P Q+Q
Sbjct: 359 HAPMSPGSSGGGGQP----LARTPQP----SSPMDQMGKMRPQP----YGGTNPYSQQQG 406
Query: 581 PSSVPVQAQA---TSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQ 637
P S P Q G+Q P Y + Q A L QQ Q
Sbjct: 407 PPSGPQQGHGYPGQPYGSQTP----------QRYPMTMQGRAQSAMGGLSYTQQIPPYGQ 456
Query: 638 QKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPG 697
Q Q Q + QQ Q ++ PP Q S+ QQ + P
Sbjct: 457 QGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQ------PQSQPPQ 510
Query: 698 MNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLY 757
+ + P S P P + P ++ P + + AQ P Q PQ
Sbjct: 511 LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA- 569
Query: 758 GMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLN 817
S ++Q A P PQ+ Q +S Q+S GS S
Sbjct: 570 --PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELS----QDSFGSQASS--------- 614
Query: 818 PGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMS 877
P ++ + GGQ NLS Q+ +S
Sbjct: 615 -------APSMTSSKGGQEDM-------NLSLQSRPSS---------------------- 638
Query: 878 SPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAP--PPTAPQQGLPGL-SPA 934
P S ++ + PM + + S S+Q S PA +P P T+P LPG+ P+
Sbjct: 639 LPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH--LPGIRGPS 696
Query: 935 GPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELP 971
+G SPAS R+G P G ++P
Sbjct: 697 PSPVG----SPASVAQSRSG----PLSPAAVPGNQMP 725
Score = 47.0 bits (110), Expect = 9e-05
Identities = 121/528 (22%), Positives = 172/528 (32%), Gaps = 95/528 (17%)
Query: 526 GQGSPGSGQSKPA----LMAYL-PQQLSHI----SHEQNSLFLMKPKPGNMPFRSLVPPG 576
GQ SPG + L Y PQQ SH +H+ NS + P RS PP
Sbjct: 175 GQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYY---------PNRSAYPPP 225
Query: 577 QEQNPSS-----VPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQ 631
S P A + G++PP S AS+ +SS + Q+ A+
Sbjct: 226 APAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGG 285
Query: 632 KQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQY----QDPTQGSFPQQVGQ 687
+ L Q L + + +Q + P Y QD G P +
Sbjct: 286 TPQPTATPTLNQL--------LTSPSSARGYQGY---PGGDYSGGPQDGGAGKGPADMAS 334
Query: 688 FTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPG 747
+AA + Q + PM PG + P Q G
Sbjct: 335 QCWGAAAAAAAAAAASGGAQ------QRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMG 388
Query: 748 SQNMPQSSLYGMASGITQIVAQPP-PQATNGHAHIPRQTNVGQNTSVSA-AYGQNSLGSS 805
PQ YG + +Q P PQ +G+ P + Q ++ Q+++G
Sbjct: 389 KMR-PQP--YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL 445
Query: 806 GLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASS 865
+QQ PP + P+ GQ GQTP + SP
Sbjct: 446 SYTQQI-----------PPYGQQGPSGYGQQ------------GQTPYYNQQSPHP---- 478
Query: 866 FHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQ----QRTSAPAPAPPP 921
QQ + + Q A P+ P S + S PP S Q +PAP P
Sbjct: 479 -QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ 537
Query: 922 TAPQQGLPGLSP--AGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELPFAYSGQ-- 977
+ Q P P + P+ + Q Q + L AYP + Q AYS Q
Sbjct: 538 QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF 597
Query: 978 --PGGSGLSSVAGHTDLIDSLLKNRTSEEWM--------SDLDDLLGS 1015
P S S+ ++ +E M S L DL GS
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645
Score = 40.0 bits (92), Expect = 0.011
Identities = 74/322 (22%), Positives = 111/322 (34%), Gaps = 57/322 (17%)
Query: 667 TRPPPQYQDPTQGSFPQQVGQF----TGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMG 722
+R PPQ Q Q QF T S + P T P G P
Sbjct: 1322 SRYPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPA 1381
Query: 723 PGH-ASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQA------- 774
H + S+P ++GQ Q P +Q P S Q AQP PQ
Sbjct: 1382 KRHEGEMYSVPYSTGQGQPQQQQLPPAQPQPASQ---------QQAAQPSPQQDVYNQYG 1432
Query: 775 ----TNGHAHIPRQTNVGQNTSVSAAYGQNSLGSS-GLSQQHNKGTLNPGLTKPPVPRVS 829
A R+ G +G++ + + G + Q N + P + P+ + S
Sbjct: 1433 NAYPATATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQN---MPPQMMGGPI-QAS 1488
Query: 830 PAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAA--------SSFHMQQQAHLKMSSPQF 881
+ Q + WQ + + ++ +P A H Q+A+ + S P
Sbjct: 1489 AEVAQQGTMWQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSH 1548
Query: 882 SQAVP----NRPMAPMSSAAAVGSLLPPVSAQQ---RTSAPAPAPPPTAPQQGLPGLSP- 933
P + P+ PM+ + PP S Q + S+PAP P P + P SP
Sbjct: 1549 GTRQPPYGPSAPVPPMTRPPP-SNYQPPPSMQNHIPQVSSPAPLPRPMENRTS-PSKSPF 1606
Query: 934 ---------AGPELGAFSQSPA 946
AGP + A +PA
Sbjct: 1607 LHSGMKMQKAGPPVPASHIAPA 1628
Score = 38.1 bits (87), Expect = 0.042
Identities = 82/369 (22%), Positives = 127/369 (34%), Gaps = 88/369 (23%)
Query: 281 PESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPS 340
P+S S Q E S +F + +P + + GQ + S + P
Sbjct: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641
Query: 341 LGGS--------------------------------QTLFHTSGQP-----RADNPSPNL 363
L GS Q+ F P R +PSP
Sbjct: 642 LSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVG 701
Query: 364 MPAS-AQAQN---AQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAT 419
PAS AQ+++ + A+ G +P + P G S+ + Q + Q R M +NPQ
Sbjct: 702 SPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761
Query: 420 -PAPAPGQMSTWQQT--GPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPR 476
+P PG + +Q G H+ + SY+Q NS P + P+
Sbjct: 762 YSSPQPGSALSPRQPSGGQIHTGM------------GSYQQ---NSMGSYGPQGGQYGPQ 806
Query: 477 PGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSK 536
G P QP++ L N N SA G + P+ G+ G +
Sbjct: 807 GGYP-RQPNYNAL------PNANYPSAGMAGGI------NPM---------GAGGQMHGQ 844
Query: 537 PALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFR----SLVPPG---QEQNPSSVPVQAQ 589
P + Y +SH P NMP + PPG ++ ++V +
Sbjct: 845 PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVA 904
Query: 590 ATSVGTQPP 598
A S+ +PP
Sbjct: 905 ANSIQNRPP 913
Score = 37.4 bits (85), Expect = 0.072
Identities = 69/268 (25%), Positives = 93/268 (34%), Gaps = 43/268 (16%)
Query: 727 SVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTN 786
S S P G G Q PQS+ MA G +PP A+ H+ IP
Sbjct: 1123 SKKSQPKIQPPSPAGSGSMQGPQT-PQSTSSSMAEGGD---LKPPTPASTPHSQIPPLPG 1178
Query: 787 VGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPN 846
+ ++ SV N GS Q+ N T NPG P+M N+S +
Sbjct: 1179 MSRSNSVGIQDAFND-GSDSTFQKRNSMTPNPG--------YQPSM---NTS-------D 1219
Query: 847 LSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMA-PMSSAAAVGSLLPP 905
+ G+ N P+ S + MSS Q PN M P S AA G L
Sbjct: 1220 MMGRMSYEPNKDPY---GSMRKAPGSDPFMSSGQ----GPNGGMGDPYSRAAGPG--LGN 1270
Query: 906 VSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRT 965
V+ R P P + PG+ P G Q +G++ YP +
Sbjct: 1271 VAMGPRQHYPYGGPYDRVRTE--PGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQ 1328
Query: 966 AGQEL--------PFAYSGQPGGSGLSS 985
Q+ F+ G P GS S
Sbjct: 1329 QQQQQQRHDSYGNQFSTQGTPSGSPFPS 1356
Score = 34.3 bits (77), Expect = 0.61
Identities = 107/497 (21%), Positives = 161/497 (32%), Gaps = 107/497 (21%)
Query: 78 PAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGH 137
PA+T + P P + ++ + + D DS +N N PG+
Sbjct: 1165 PASTPHSQIPPLPGMSRSN-------SVGIQDAFNDGSDSTFQKRNSMTPN------PGY 1211
Query: 138 KKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLH 197
+ + + + +S P P G K G+D SSG+ G R A L
Sbjct: 1212 QPSMNTSDMMGRMSYE--PNKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLG 1269
Query: 198 LNGGSNPSESFPL-SLNKELKQEP-VEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELI 255
N P + +P ++ EP + M TG Q NLMP N + +
Sbjct: 1270 -NVAMGPRQHYPYGGPYDRVRTEPGIGPEGNMSTGA----PQPNLMPS-NPDSGMYSPSR 1323
Query: 256 EELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPL---AQDINIK-----TEFSPAAF 307
+ + D + F + P S +Q Q N K T PA
Sbjct: 1324 YPPQQQQQQQQRHDSYGNQFSTQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKR 1383
Query: 308 EQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPAS 367
+ ++ S G GQ P + P Q S Q N N PA+
Sbjct: 1384 HEGEMYSVPYSTGQ-GQ----PQQQQLPPAQPQPASQQQAAQPSPQQDVYNQYGNAYPAT 1438
Query: 368 AQAQNAQRALAGVV-----------------------LPSQGPGGASELSSAHQLQQIAA 404
A A +R G +P Q GG + +SA QQ
Sbjct: 1439 ATAATERRPAGGPQNQFPFQFGRDRVSAPPGTNAQQNMPPQMMGGPIQ-ASAEVAQQGTM 1497
Query: 405 KQKREQMLQN--PQQATPAPAPG----------------QMSTWQQTGPSHSSLDVPY-- 444
Q R M N +Q+T + G Q + + + PSH + PY
Sbjct: 1498 WQGRNDMTYNYANRQSTGSAPQGPAYHGVNRTDEMLHTDQRANHEGSWPSHGTRQPPYGP 1557
Query: 445 -----PMEKPASPSSYK---------QDFTNSKLLMMPSVNKSSP------------RPG 478
PM +P PS+Y+ ++ L P N++SP +
Sbjct: 1558 SAPVPPMTRP-PPSNYQPPPSMQNHIPQVSSPAPLPRPMENRTSPSKSPFLHSGMKMQKA 1616
Query: 479 GPYLQPSHVNLLSHQPP 495
GP + SH+ QPP
Sbjct: 1617 GPPVPASHIAPAPVQPP 1633
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 64.7 bits (156), Expect = 4e-10
Identities = 139/583 (23%), Positives = 203/583 (34%), Gaps = 79/583 (13%)
Query: 303 SPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQ-PRADNPSP 361
+P + G Q G T P P PS G Q GQ P + SP
Sbjct: 426 TPQRYPMTMQGRAQSAMGGLSYTQQIP---PYGQQGPSGYGQQ------GQTPYYNQQSP 476
Query: 362 NLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQ--QIAAKQK--REQMLQNPQQ 417
+ P Q +Q+ PSQ P Q Q Q+ + Q +Q Q P Q
Sbjct: 477 H--PQQQQPPYSQQP------PSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQ 528
Query: 418 ATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRP 477
+PAP P Q ST QQ H PY +P + S Y+Q S + P+P
Sbjct: 529 QSPAPYPSQQSTTQQ----HPQSQPPY--SQPQAQSPYQQQQPQQPAPSTLSQQAAYPQP 582
Query: 478 GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCG-QGSPGSGQSK 536
Q + + PP L+Q+S +Q S + + Q P S
Sbjct: 583 QSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDL 642
Query: 537 PALMAYLPQ----------QLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQE--QNPSSV 584
+ LP S IS Q + P PF P + PS
Sbjct: 643 SGSIDDLPMGTEGALSPGVSTSGISSSQGE----QSNPAQSPFSPHTSPHLPGIRGPSPS 698
Query: 585 PVQAQATSVGTQPPAVSVAS--SHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQ 642
PV + A+ ++ +S A+ + P S Q ++M + R Q++ Q
Sbjct: 699 PVGSPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQ 758
Query: 643 QQQFLQRQQ-HLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQF--TGSSAAVPGMN 699
Q+ Q L+ ++ Q H YQ + GS+ Q GQ+ G P N
Sbjct: 759 MPQYSSPQPGSALSPRQPSGGQIHTGM--GSYQQNSMGSYGPQGGQYGPQGGYPRQPNYN 816
Query: 700 TLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGM 759
L N++ P AG + PMG +G Q G P +P +
Sbjct: 817 AL--PNANYPSA-GMAGGINPMG------------AGGQMHGQPGIPPYGTLPPGRMSHA 861
Query: 760 ASGITQI---VAQPPPQATNGHAHIPRQTN-VGQNTSVSAAYGQNSLGS--SGLSQQHNK 813
+ G +A PPQ +G P N Q T+V+ NS+ + G +
Sbjct: 862 SMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQG 921
Query: 814 GTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSN 856
G + G PP + +M G + QG P G T N++
Sbjct: 922 GMMGTG---PPYGQGINSMAGMINP---QGPPYSMGGTMANNS 958
Score = 50.8 bits (120), Expect = 6e-06
Identities = 155/697 (22%), Positives = 222/697 (31%), Gaps = 143/697 (20%)
Query: 320 GSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASA---QAQNAQRA 376
GS+ P SA + P+ G GQP +PS A+A Q Q++
Sbjct: 127 GSSDGVGAPPHSAAAALPPPAYG--------FGQPYGRSPSAVAAAAAAVFHQQHGGQQS 178
Query: 377 LAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQ-ATPAPAPGQMSTWQQTGP 435
L S G GG + Q + P + A P PAP + + G
Sbjct: 179 PGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSSPRGGT 238
Query: 436 SHSSLDVPYPMEKP----ASPSSYKQDFTNSKLLMM------------------PSVNK- 472
S + P AS SS F + M P++N+
Sbjct: 239 PGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQL 298
Query: 473 ----SSPR-----PGGPYLQPSHVNLLSHQPPSNLNQ---NSANNQGSVLDYGNTKPLSH 520
SS R PGG Y P +Q +A + G + SH
Sbjct: 299 LTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSH 358
Query: 521 YKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQN 580
+ S G GQ +A PQ S + + M+P+P + P Q+Q
Sbjct: 359 HAPMSPGSSGGGGQP----LARTPQP----SSPMDQMGKMRPQP----YGGTNPYSQQQG 406
Query: 581 PSSVPVQAQA---TSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQ 637
P S P Q G+Q P Y + Q A L QQ Q
Sbjct: 407 PPSGPQQGHGYPGQPYGSQTP----------QRYPMTMQGRAQSAMGGLSYTQQIPPYGQ 456
Query: 638 QKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPG 697
Q Q Q + QQ Q ++ PP Q S+ QQ + P
Sbjct: 457 QGPSGYGQQGQTPYYNQQSPHPQQQQPPYSQQPPSQTPHAQPSYQQQ------PQSQPPQ 510
Query: 698 MNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLY 757
+ + P S P P + P ++ P + + AQ P Q PQ
Sbjct: 511 LQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPA- 569
Query: 758 GMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLN 817
S ++Q A P PQ+ Q +S Q+S GS S
Sbjct: 570 --PSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQELS----QDSFGSQASS--------- 614
Query: 818 PGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMS 877
P ++ + GGQ NLS Q+ +S
Sbjct: 615 -------APSMTSSKGGQEDM-------NLSLQSRPSS---------------------- 638
Query: 878 SPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAP--PPTAPQQGLPGL-SPA 934
P S ++ + PM + + S S+Q S PA +P P T+P LPG+ P+
Sbjct: 639 LPDLSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPH--LPGIRGPS 696
Query: 935 GPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELP 971
+G SPAS R+G P G ++P
Sbjct: 697 PSPVG----SPASVAQSRSG----PLSPAAVPGNQMP 725
Score = 47.0 bits (110), Expect = 9e-05
Identities = 121/528 (22%), Positives = 172/528 (32%), Gaps = 95/528 (17%)
Query: 526 GQGSPGSGQSKPA----LMAYL-PQQLSHI----SHEQNSLFLMKPKPGNMPFRSLVPPG 576
GQ SPG + L Y PQQ SH +H+ NS + P RS PP
Sbjct: 175 GQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPNHQYNSYY---------PNRSAYPPP 225
Query: 577 QEQNPSS-----VPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQ 631
S P A + G++PP S AS+ +SS + Q+ A+
Sbjct: 226 APAYALSSPRGGTPGSGAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGG 285
Query: 632 KQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQY----QDPTQGSFPQQVGQ 687
+ L Q L + + +Q + P Y QD G P +
Sbjct: 286 TPQPTATPTLNQL--------LTSPSSARGYQGY---PGGDYSGGPQDGGAGKGPADMAS 334
Query: 688 FTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPG 747
+AA + Q + PM PG + P Q G
Sbjct: 335 QCWGAAAAAAAAAAASGGAQ------QRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMG 388
Query: 748 SQNMPQSSLYGMASGITQIVAQPP-PQATNGHAHIPRQTNVGQNTSVSA-AYGQNSLGSS 805
PQ YG + +Q P PQ +G+ P + Q ++ Q+++G
Sbjct: 389 KMR-PQP--YGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTPQRYPMTMQGRAQSAMGGL 445
Query: 806 GLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASS 865
+QQ PP + P+ GQ GQTP + SP
Sbjct: 446 SYTQQI-----------PPYGQQGPSGYGQQ------------GQTPYYNQQSPHP---- 478
Query: 866 FHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQ----QRTSAPAPAPPP 921
QQ + + Q A P+ P S + S PP S Q +PAP P
Sbjct: 479 -QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQ 537
Query: 922 TAPQQGLPGLSP--AGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELPFAYSGQ-- 977
+ Q P P + P+ + Q Q + L AYP + Q AYS Q
Sbjct: 538 QSTTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRF 597
Query: 978 --PGGSGLSSVAGHTDLIDSLLKNRTSEEWM--------SDLDDLLGS 1015
P S S+ ++ +E M S L DL GS
Sbjct: 598 PPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645
Score = 40.8 bits (94), Expect = 0.007
Identities = 43/142 (30%), Positives = 59/142 (41%), Gaps = 35/142 (24%)
Query: 359 PSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNP--Q 416
P PNLMP++ + G+ PS+ P QQ +Q+R N
Sbjct: 1305 PQPNLMPSNPDS--------GMYSPSRYPP-----------QQQQQQQQRHDSYGNQFST 1345
Query: 417 QATPA--PAPGQMST-WQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKS 473
Q TP+ P P Q +T +QQ S +P PME SPS K F +S + M
Sbjct: 1346 QGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMENRTSPS--KSPFLHSGMKM------- 1396
Query: 474 SPRPGGPYLQPSHVNLLSHQPP 495
+ GP + SH+ QPP
Sbjct: 1397 --QKAGPPVPASHIAPAPVQPP 1416
Score = 38.1 bits (87), Expect = 0.042
Identities = 82/369 (22%), Positives = 127/369 (34%), Gaps = 88/369 (23%)
Query: 281 PESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPS 340
P+S S Q E S +F + +P + + GQ + S + P
Sbjct: 582 PQSQQSQQTAYSQQRFPPPQELSQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPD 641
Query: 341 LGGS--------------------------------QTLFHTSGQP-----RADNPSPNL 363
L GS Q+ F P R +PSP
Sbjct: 642 LSGSIDDLPMGTEGALSPGVSTSGISSSQGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVG 701
Query: 364 MPAS-AQAQN---AQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAT 419
PAS AQ+++ + A+ G +P + P G S+ + Q + Q R M +NPQ
Sbjct: 702 SPASVAQSRSGPLSPAAVPGNQMPPRPPSGQSDSIMHPSMNQSSIAQDRGYMQRNPQMPQ 761
Query: 420 -PAPAPGQMSTWQQT--GPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPR 476
+P PG + +Q G H+ + SY+Q NS P + P+
Sbjct: 762 YSSPQPGSALSPRQPSGGQIHTGM------------GSYQQ---NSMGSYGPQGGQYGPQ 806
Query: 477 PGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSK 536
G P QP++ L N N SA G + P+ G+ G +
Sbjct: 807 GGYP-RQPNYNAL------PNANYPSAGMAGGI------NPM---------GAGGQMHGQ 844
Query: 537 PALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFR----SLVPPG---QEQNPSSVPVQAQ 589
P + Y +SH P NMP + PPG ++ ++V +
Sbjct: 845 PGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQVGSGMCPPPGGMNRKTQETAVAMHVA 904
Query: 590 ATSVGTQPP 598
A S+ +PP
Sbjct: 905 ANSIQNRPP 913
Score = 37.4 bits (85), Expect = 0.072
Identities = 68/311 (21%), Positives = 99/311 (31%), Gaps = 45/311 (14%)
Query: 669 PPPQY--QDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHA 726
PPP ++ S P+ S ++ G T ++SS + G+L P P
Sbjct: 1113 PPPDIFAAADSKKSQPKIQPPSPAGSGSMQGPQTPQSTSSS----MAEGGDLKPPTPAST 1168
Query: 727 SVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVA-QPPPQATNGHAHIPRQT 785
S +P G + N S + + +T QP ++ + +
Sbjct: 1169 PHSQIPPLPGMSRSNSVGIQDAFNDGSDSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEP 1228
Query: 786 NVGQNTSVSAAYGQNSLGSSGLSQQHNKG-----TLNPGLTKPPVP-------------- 826
N S+ A G + SSG G PGL +
Sbjct: 1229 NKDPYGSMRKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRV 1288
Query: 827 RVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFS-QAV 885
R P +G + + PNL P + SP QQQ QFS Q
Sbjct: 1289 RTEPGIGPEGNMSTGAPQPNLMPSNPDSGMYSPSRYPPQQQQQQQQRHDSYGNQFSTQGT 1348
Query: 886 PNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSP----------AG 935
P+ P QQ+ S+PAP P P + P SP AG
Sbjct: 1349 PSGSPFPSQQTTM-------YQQQQQVSSPAPLPRPMENRTS-PSKSPFLHSGMKMQKAG 1400
Query: 936 PELGAFSQSPA 946
P + A +PA
Sbjct: 1401 PPVPASHIAPA 1411
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 58.5 bits (140), Expect = 3e-08
Identities = 91/408 (22%), Positives = 142/408 (34%), Gaps = 40/408 (9%)
Query: 560 MKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAA 619
M P+ + G P S+ Q + G P +++V S+ L QQ A
Sbjct: 101 MPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVAL 160
Query: 620 VMKQHQLLLDQQKQ-------REQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQ 672
+Q Q QQ+Q ++QQQ+ Q QQ +QQ Q++QQ Q+ + Q
Sbjct: 161 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQ--QQQQQ 218
Query: 673 YQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLP 732
+ QQ+ Q + + + Q L P P
Sbjct: 219 HLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQP 278
Query: 733 TNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQP--PPQATNGHAHIPRQTNVGQN 790
Q P SQ +PQ + Q QP PP A N + +P Q+
Sbjct: 279 -----------QPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQS----Q 323
Query: 791 TSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQ 850
T + Q G +Q K P + + P V P + Q ++ Q +
Sbjct: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ--PPVQPQVQQQQTAVQTAQAAQM--V 379
Query: 851 TPGNSNVSPFTAASSFHMQQQ---AHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVS 907
PG ++ A H++ + + P S + +PMA +S ++ P
Sbjct: 380 APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439
Query: 908 AQQRTSAPAPAPPPTAPQQGLPGLSP-------AGPELGAFSQSPASQ 948
Q +T P PP +PQ G P P P +F SP+ Q
Sbjct: 440 QQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ 487
Score = 55.8 bits (133), Expect = 2e-07
Identities = 115/469 (24%), Positives = 165/469 (35%), Gaps = 79/469 (16%)
Query: 478 GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKP 537
GGP + + + PP Q S GS+ G LS GQ PG+ P
Sbjct: 90 GGPAAGAAGIGM----PPRGPGQ-SLGGMGSLGAMGQPMSLS------GQPPPGTSGMAP 138
Query: 538 ALMAYLP-------------------QQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQE 578
MA + QQ +Q +L + + F++ Q+
Sbjct: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
Query: 579 QNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQ 638
Q + V Q Q Q + N QQQ + Q QL QQ+Q++QQQ
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Query: 639 KHLQQQQFLQRQ---------------QHLLAEQEKQQFQRHLTRPPPQYQ-------DP 676
QQQQ LQ Q L +Q +Q +PPPQ Q P
Sbjct: 259 ---QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQP 315
Query: 677 TQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSG 736
+Q Q + A+PG + P F +A ++ P V T
Sbjct: 316 SQLPPQSQTQPLVSQAQALPGQMLY----TQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQ 371
Query: 737 QQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAA 796
PG Q + ++ +A G I A+ PP T + IP +++ A
Sbjct: 372 TAQAAQMVAPGVQMITEA----LAQGGMHIRARFPP--TTAVSAIP-SSSIPLGRQPMAQ 424
Query: 797 YGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSN 856
Q+SL LS + + PP P+ SP GQ SS + + SG P S+
Sbjct: 425 VSQSSLPM--LSSPSPGQQVQTPQSMPPPPQPSP-QPGQPSSQPNSNVS--SGPAPSPSS 479
Query: 857 VSPFTAASSFHMQQQAHLKMSSPQ-FSQAVP---NRPMAPMSSAAAVGS 901
P S Q+ + +PQ FS P N P+ P S + GS
Sbjct: 480 FLP----SPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 524
Score = 46.6 bits (109), Expect = 1e-04
Identities = 106/467 (22%), Positives = 159/467 (34%), Gaps = 73/467 (15%)
Query: 309 QEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASA 368
Q G P A G GP SLGG +L GQP + + P P ++
Sbjct: 86 QSLTGGPAAGAAGIGMPPRGPGQ--------SLGGMGSL-GAMGQPMSLSGQPP--PGTS 134
Query: 369 QAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMS 428
A+ P + QLQQ+A +Q+++Q QQ Q
Sbjct: 135 GMAPHSMAVVSTATPQ----------TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQ 184
Query: 429 TWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVN 488
QQ S++ + +Q L+ + N+ + LQ +
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQ--RIA 242
Query: 489 LLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLS 548
L Q Q Q L +A P Q +P LPQQL
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQAL-----------QAQPPIQQPPMQQPQPPPSQALPQQLQ 291
Query: 549 HISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNS 608
+ H Q+ +P P + PP + PS +P Q+Q + +Q A+ +
Sbjct: 292 QMHHTQHH----QPPP-----QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 609 SPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQ---HLLAEQEKQQFQRH 665
P L + V++Q + Q Q +QQQ +Q Q Q ++ E Q
Sbjct: 343 PP-LKFVRAPMVVQQPPV----QPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHI 397
Query: 666 LTRPPP--QYQDPTQGSFP---QQVGQFTGSSAAV-----PGMNTLGP-SNSSCPRVFPQ 714
R PP S P Q + Q + SS + PG P S P+ PQ
Sbjct: 398 RARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQ 457
Query: 715 AG-------NLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQS 754
G + + GP + S LP+ S Q +Q P + PQ+
Sbjct: 458 PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQP----SQSPVTARTPQN 500
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 57.0 bits (136), Expect = 9e-08
Identities = 139/587 (23%), Positives = 207/587 (35%), Gaps = 90/587 (15%)
Query: 357 DNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQ 416
D P P + AS +A+ + + + A Q Q Q+ L PQ
Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQ 2528
Query: 417 QATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLL---MMPSVNKS 473
A P G + Q P + P P++ PA ++ +L + SV +
Sbjct: 2529 AAGSQPPAGPPAVQPQPQPQPQTQ--PQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGT 2586
Query: 474 SPRPGGPYLQPSHVNLLSHQPPS---NLNQNSANN--QGSVLDYGNTKPLSHYKADC--- 525
S P G VN ++ P + ++N+ A+ G++ G + P
Sbjct: 2587 S-MPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPR 2645
Query: 526 GQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVP 585
GSP + MA + S +++ P P RSLVP
Sbjct: 2646 AVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQ---------- 2695
Query: 586 VQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQ 645
+QAT G Q P ++ +H QLL QQ+Q++QQQ+ QQQQ
Sbjct: 2696 -VSQAT--GVQLPGKTITPAH-----------------FQLLRQQQQQQQQQQQQQQQQQ 2735
Query: 646 FLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSN 705
Q+QQ Q++QQ Q +Q PQ GQ S A + + L P +
Sbjct: 2736 QQQQQQ-----QQQQQ----------QTTTTSQVQVPQIQGQ-AQSPAQIKAVGKLTPEH 2779
Query: 706 SSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQ 765
++ Q + P P + S+ P + Q +Q P Q PQ +T
Sbjct: 2780 --LIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQ-PPQQQSPQ---------LTT 2827
Query: 766 IVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPV 825
+ A P G Q V + T V + L + G Q L KPPV
Sbjct: 2828 VTAPRPGALLTGTTVANLQ--VARLTRVPT----SQLQAQGQMQTQAPQPAQVALAKPPV 2881
Query: 826 PRVSPAM----GGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQF 881
V A+ G G+ GQ A HMQQ LK + Q
Sbjct: 2882 VSVPAAVVSSPGVTTLPMNVAGISVAIGQP--QKAAGQTVVAQPVHMQQLLKLKQQAVQQ 2939
Query: 882 SQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGL 928
+A+ +P A AA + ++AQQ T+ A A Q L
Sbjct: 2940 QKAI--QPQAAQGPAA----VQQKITAQQITTPGAQQKVAYAAQPAL 2980
Score = 38.5 bits (88), Expect = 0.032
Identities = 72/309 (23%), Positives = 111/309 (35%), Gaps = 55/309 (17%)
Query: 350 TSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKRE 409
T+ P+ +L+P +QA GV LP + ++ AH Q+ +Q+++
Sbjct: 2679 TTNLTPVQTPARSLVPQVSQA-------TGVQLPGK------TITPAHF--QLLRQQQQQ 2723
Query: 410 QMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQ--DFTNSKLLMM 467
Q Q QQ Q QQ + S + VP + SP+ K T L+ M
Sbjct: 2724 QQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKM 2783
Query: 468 PSVN-KSSPRPGGPYLQ------PSHVNLLSHQPPS----NLNQNSANNQGSVLDYGNTK 516
+ P+P P Q + V + + QPP L +A G++L
Sbjct: 2784 QKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVA 2843
Query: 517 PLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPG 576
L + S Q + A P Q++ L KP ++P + PG
Sbjct: 2844 NLQVARLTRVPTSQLQAQGQMQTQAPQPAQVA----------LAKPPVVSVPAAVVSSPG 2893
Query: 577 QEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQH-QLLLDQQKQRE 635
V T P V+ S P ++ Q H Q LL ++Q
Sbjct: 2894 ----------------VTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAV 2937
Query: 636 QQQKHLQQQ 644
QQQK +Q Q
Sbjct: 2938 QQQKAIQPQ 2946
Score = 36.2 bits (82), Expect = 0.16
Identities = 78/336 (23%), Positives = 117/336 (34%), Gaps = 30/336 (8%)
Query: 697 GMNTLGPSNSSCPRVFPQAGNLMPMGP--GHASVSSLPTNSGQQDRGVAQFPGSQNMPQS 754
G PS P + P GP G +++ N + A F SQ +
Sbjct: 1438 GRTVAFPSTHPPRTAAPTTASAAPQGPLRGRPPIATFSANP-EAKAAAAPFQTSQASASA 1496
Query: 755 SLYGMASGITQIVAQPPPQA----TNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQ 810
+ AS + + P T A P Q Q + S A GQ++L +
Sbjct: 1497 PRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPP-QPQAPSHAAGQSALPQRLVLPS 1555
Query: 811 HNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQ----TPGNSNVSPFTAASSF 866
+ L G + +++ G Q+ Q + L Q T +S + TA
Sbjct: 1556 QAQARLPSGEVVK-IAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPL 1614
Query: 867 HMQQQAHLKMSSP--QFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAP 924
+Q +S+P + +A M +S A AV L + A P+P P P
Sbjct: 1615 QLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGALG-----SKPPAGGPSPAPLTP 1669
Query: 925 QQGLPGL----SPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQELPFAYSGQPGG 980
Q G+PG + A E G S+ PAS +GG TQ R + L Y
Sbjct: 1670 QVGVPGRVAVNALAVGEPGTASK-PASPIGGP-----TQEEKTRLLKERLDQIYLVNERR 1723
Query: 981 SGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ 1016
+ V G L L + +W LD G +
Sbjct: 1724 CSQAPVYGRDLLRICALPSHGRVQWRGSLDGRRGKE 1759
Score = 31.6 bits (70), Expect = 4.0
Identities = 45/169 (26%), Positives = 62/169 (36%), Gaps = 7/169 (4%)
Query: 833 GGQNSSWQHQ---GMPNLSGQT-PGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNR 888
G QN Q Q P G+ P + N P AA + + S Q Q +
Sbjct: 6 GPQNVQHQLQRSRACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQIQQLMNRS 65
Query: 889 PMAPMSSAAAVGSLLPPVSA-QQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPAS 947
P + + S+ P V QQ T AP P P PT+P P E G+ S +
Sbjct: 66 PATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSPGFQF-SAQPRRFEHGSPSYIQVT 124
Query: 948 QMGGRAGLHCTQAYPVRTAGQELPFAYSGQPG-GSGLSSVAGHTDLIDS 995
+ + P GQ L +G PG G GL S + +D+
Sbjct: 125 SPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDA 173
>gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]
Length = 1426
Score = 57.0 bits (136), Expect = 9e-08
Identities = 193/847 (22%), Positives = 292/847 (34%), Gaps = 160/847 (18%)
Query: 155 LPPASPLGQS--DKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSL 212
+P PL S D P G G+ L + D +L++N GSN S+ P +
Sbjct: 680 IPVEGPLSPSRGDFPKGIPPQMGPGRE-LEFGMVPSGMKGDVNLNVNMGSN-SQMIPQKM 737
Query: 213 NKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVP-------DE 265
+E P E L G+ +Q ++P L E +E +P +
Sbjct: 738 -REAGAGPEEMLKLRPGGSDMLPAQQKMVP-LPFGEHPQQEYGMGPRPFLPMSQGPGSNS 795
Query: 266 DMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQT 325
+++L +++ PL N T + A Q LG + AG
Sbjct: 796 GLRNLREPIGPDQRTNSRLSHMPPLPLNPSSN-PTSLNTAPPVQRGLGRKPLDISVAGSQ 854
Query: 326 FLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQ 385
P P+ SP++ H P +PS NL +Q LAG++
Sbjct: 855 VHSPGINPLK--SPTM-------HQVQSPMLGSPSGNLKSPQTPSQ-----LAGMLA--- 897
Query: 386 GPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYP 445
GP A+ + S L AA L++P + PAP+PG S+ + P
Sbjct: 898 GPAAAASIKSPPVLGSAAASPVH---LKSP--SLPAPSPGWTSSPKP------------P 940
Query: 446 MEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPS--------- 496
++ P P ++K T + M+ +V P P QP+ VN+ P S
Sbjct: 941 LQSPGIPPNHKAPLTMASPAMLGNVESGGP-PPPTASQPASVNIPGSLPSSTPYTMPPEP 999
Query: 497 NLNQNSAN---NQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLP--QQLSHIS 551
L+QN + ++ S ++ PL H S S PA LP + +
Sbjct: 1000 TLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASS--DDDSPPARSPNLPSMNNMPGMG 1057
Query: 552 HEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPY 611
+ + P P +P +L P G Q S +VG P V P
Sbjct: 1058 INTQNPRISGPNP-VVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVP----MGPG 1112
Query: 612 LSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPP 671
L S H ++ H Q+ + Q + Q Q + P
Sbjct: 1113 LMS---------HNPIMG----------HGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPF 1153
Query: 672 QYQDPT--QGSFPQQVGQFTGSSAAVPGMNTLG-PSNSSCPRVFPQAGNLMPMGPGHASV 728
+ P+ QGSFP +G PG LG PSN P+ A P GPG
Sbjct: 1154 PHNGPSGGQGSFPGGMG--------FPGEGPLGRPSN--LPQSSADAALCKPGGPGGPDS 1203
Query: 729 -----SSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPR 783
+S+P+ D PG+ +P+ L ++I+ P T + PR
Sbjct: 1204 FTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDL-------SRIIPSEKPSQT--LQYFPR 1254
Query: 784 QTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQG 843
G+ G H +G + G P + P MGG G
Sbjct: 1255 ----------GEVPGRKQPQGPGPGFSHMQGMM--GEQAPRMGLALPGMGGPGP----VG 1298
Query: 844 MPNLS-GQTPGNSNVSPFTAASSFHMQQQA-HLKMSSPQFSQAVPNRPMAPMSSAAAVGS 901
P++ G P +P + H +M SP S +P +P + AAAVG
Sbjct: 1299 TPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQS-TMPGQPTLMSNPAAAVGM 1357
Query: 902 LLPPVSAQQRTSA-----PAPAPPP---------TAPQQGL---PGLSPAGPE----LGA 940
+ + R A P P P PQQ + P + P G +G
Sbjct: 1358 ----IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGG 1413
Query: 941 FSQSPAS 947
FSQ P +
Sbjct: 1414 FSQGPGN 1420
Score = 46.6 bits (109), Expect = 1e-04
Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 7/100 (7%)
Query: 886 PNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAP--PPTAPQQGLPGLSPAGPELGAFSQ 943
PN P+ PM + + +G P + Q S A P PP G PGL P +G SQ
Sbjct: 1068 PN-PVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMG-PGLMSHNPIMGHGSQ 1125
Query: 944 SPASQMGGRAGLHCTQAYP-VRTAGQELPFAYSGQPGGSG 982
P GR G Q +P V++ Q++PF ++G GG G
Sbjct: 1126 EPPMVPQGRMGF--PQGFPPVQSPPQQVPFPHNGPSGGQG 1163
Score = 45.8 bits (107), Expect = 2e-04
Identities = 158/746 (21%), Positives = 255/746 (34%), Gaps = 132/746 (17%)
Query: 354 PRADNPSPNLMPASAQAQNAQRALAGVV--LPSQGPGGASELSSAHQLQQIAAKQKREQM 411
PR+ PS A+ + AQ+ A VV ++ A+E Q++ I + + +
Sbjct: 151 PRSSTPSHGQTTAT-EPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHI-QNI 208
Query: 412 LQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVN 471
N + + AP Q+S + P P + PA + + N++L P +
Sbjct: 209 SNNKTERSTAPLNTQISALRNDPK-------PLPQQPPAPANQDQNSSQNTRLQPTPPIP 261
Query: 472 KSSPRPGGP-------------YLQPSHVNLLSHQ--PPSNLNQNSANNQGSV--LDYGN 514
+P+P P L PS + S PP NS N +V + G+
Sbjct: 262 APAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGS 321
Query: 515 TKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLS--HISHEQNSLFLMKP-----KPGNM 567
+ KA P +P + P LS + H + SL ++ P
Sbjct: 322 NSSSADPKA---PPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEK 378
Query: 568 PFRSLVPPGQEQNPSSV---------PVQ---AQATSVGTQP------------------ 597
F G +QNP + P+Q AQ+ S+G P
Sbjct: 379 EFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDV 438
Query: 598 ---PAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLL 654
P V S NS M Q+ + +Q ++K +Q+Q + +Q L
Sbjct: 439 PFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQ 498
Query: 655 AEQEKQQFQRHLTR-PPPQYQ-DPTQGSFPQQVGQFTGS-----SAAVPGMNTLGPSNSS 707
Q R + R PPP YQ P++G P F+ S GM S
Sbjct: 499 DMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGS 558
Query: 708 CPRVFPQAG--NLMPMGPGHASVSSLPTNSG-QQDRGVAQFPGSQNMPQSSLYGMASGIT 764
R+ AG N GP + +S P SG V + P +N P G+ SG
Sbjct: 559 QMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQ--GIFSGPG 616
Query: 765 QIVAQPPPQATNGHAHIPR--QTNVGQNTSVSAAYGQNSLGSSGL---SQQHNKGTLNPG 819
+ P PQ + + + +G ++ + S+ + + SQ+H + NP
Sbjct: 617 RGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPI 676
Query: 820 LTKPPV-----------PRVSPAMGGQNSSWQHQGMP-------NLSGQTPGNSNVSP-- 859
+ PV P+ P G + +P NL+ NS + P
Sbjct: 677 FPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQK 736
Query: 860 --------------FTAASSFHMQQQAHLKM---SSPQFSQAVPNRPMAPMS----SAAA 898
S QQ + + PQ + RP PMS S +
Sbjct: 737 MREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSG 796
Query: 899 VGSLLPPVSAQQRTSAPAPAPPPTA--PQQGLPGLSPAGPELGAFSQSPASQMGGRAGLH 956
+ +L P+ QRT++ PP P L+ A P + P + +H
Sbjct: 797 LRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVH 856
Query: 957 CTQAYPVRT-AGQELPFAYSGQPGGS 981
P+++ ++ G P G+
Sbjct: 857 SPGINPLKSPTMHQVQSPMLGSPSGN 882
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 55.8 bits (133), Expect = 2e-07
Identities = 112/499 (22%), Positives = 170/499 (34%), Gaps = 55/499 (11%)
Query: 468 PSVNKSSPRPGGPYLQPSHV--NLLSHQPPSNLNQNSANNQGSVLDYGNTKP-------L 518
P ++ P PG +QP+ + QPP S+N G + KP L
Sbjct: 370 PKAGQTQPNPGILPIQPALTPRKRATVQPPPQA-AGSSNQPGLLASVPQPKPQAPPSQPL 428
Query: 519 SHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQE 578
+A Q P Q+ LP Q Q LFL + + P PP Q+
Sbjct: 429 PQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQP-----PPAQQ 483
Query: 579 QNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQ 638
Q + Q QA + Q AV A+ + Q Q QL+ + +Q++QQQ
Sbjct: 484 QPAGTFYQQQQAQTQQFQ--AVHPATQQPAIAQFPVVSQGG--SQQQLMQNFYQQQQQQQ 539
Query: 639 KHLQQQQFLQ--RQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVP 696
+ QQQQ QQ L+ +Q Q Q PT + Q Q + P
Sbjct: 540 QQQQQQQLATALHQQQLMTQQAALQ------------QKPTMAAGQQPQPQPAAAPQPAP 587
Query: 697 GMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSL 756
P+ + R P+ P V SL S + + ++ S++
Sbjct: 588 AQE---PAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQRAGHRRILSDVTHSAV 644
Query: 757 YGM-ASGITQIVAQPPPQATNGHAHIPRQTNVGQ-NTSVSAAYGQ------NSLGSSGLS 808
+G+ AS TQ++ +A+ + T G TS Y N S
Sbjct: 645 FGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQQNVYNPSEGSTWNPFDDDNFS 704
Query: 809 QQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHM 868
+ + LN K + +GG S G + G ++ S TA
Sbjct: 705 KLTAEELLNKDFAKLGEGKHPEKLGGSAES-LIPGFQSTQGDAFATTSFSAGTAEKRKGG 763
Query: 869 QQQAH----LKMSSPQFSQAVPNRP------MAPMSSAAAVGSLLPPVSAQQRTSAPAPA 918
Q L +S P VP+ P + ++ + LLP TS
Sbjct: 764 QTVDSGLPLLSVSDPFIPLQVPDAPEKLIEGLKSPDTSLLLPDLLPMTDPFGSTSDAVIE 823
Query: 919 PPPTAPQQGLPGLSPAGPE 937
A + +PGL P P+
Sbjct: 824 KADVAVESLIPGLEPPVPQ 842
Score = 46.2 bits (108), Expect = 2e-04
Identities = 104/427 (24%), Positives = 143/427 (33%), Gaps = 85/427 (19%)
Query: 452 PSSYKQDFTNSKLLM----MPSVNKSS-----PRPGGPYLQPSHVNLLSHQPPSNLNQNS 502
P Y+ + + KLL +P+V S P P ++ S QP + L
Sbjct: 302 PDIYQVSYFSFKLLKKECPIPNVQNSPIPAKLPEP----VKASEAAAKKTQPKARLTDPI 357
Query: 503 ANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM------AYLPQQLSHISHEQNS 556
+ S+ P KA Q +PG +PAL P Q + S++
Sbjct: 358 PTTETSIA------PRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGL 411
Query: 557 LFLM-KPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQ 615
L + +PKP P + L P Q + P + P Q S Q L +Q
Sbjct: 412 LASVPQPKPQAPPSQPL-PQTQAKQPQAPPTPQQTPSTQAQG--------------LPAQ 456
Query: 616 QQAAVMKQHQLLLDQQKQREQQQKHLQQQQ----FLQRQQHLLAEQEKQQFQRHLTRPPP 671
QA Q QL L QQ+Q QQQ QQQ F Q+QQ + QQFQ P
Sbjct: 457 AQATPQHQQQLFLKQQQQ--QQQPPPAQQQPAGTFYQQQQ-----AQTQQFQ----AVHP 505
Query: 672 QYQDPTQGSFP---------------------QQVGQFTGSSAAVPGMNTLGPSNSSCPR 710
Q P FP QQ Q A L ++ +
Sbjct: 506 ATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQ 565
Query: 711 VFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQP 770
A P A+ P V Q P Q P ++ G G + P
Sbjct: 566 KPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSP 625
Query: 771 PPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQ-QHNKGTLNPGLTKPPVPRVS 829
Q GH I + + SA +G + S+ L Q + +LN + P S
Sbjct: 626 KTQRA-GHRRIL------SDVTHSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGS 678
Query: 830 PAMGGQN 836
P QN
Sbjct: 679 PRTSQQN 685
Score = 37.4 bits (85), Expect = 0.072
Identities = 61/292 (20%), Positives = 92/292 (31%), Gaps = 22/292 (7%)
Query: 333 PVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASE 392
P+ T S+ Q +P+A PN Q R A V P Q G +++
Sbjct: 356 PIPTTETSIAPRQ-------RPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQ 408
Query: 393 LSSAHQLQQIAAKQKREQMLQNPQQATP--APAPGQMSTWQQTGPSHSSLDVPYPMEKPA 450
+ Q + Q L Q P P P Q + Q G P + A
Sbjct: 409 PGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQG---------LPAQAQA 459
Query: 451 SPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVL 510
+P +Q F + + +P G + Q Q Q A Q V+
Sbjct: 460 TPQHQQQLFLKQQ-QQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVV 518
Query: 511 DYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQ---LSHISHEQNSLFLMKPKPGNM 567
G ++ Q Q + L L QQ + +Q +P
Sbjct: 519 SQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQ 578
Query: 568 PFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAA 619
P + P ++ PV+ Q T PPAV + +P S + Q A
Sbjct: 579 PAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKTQRA 630
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 55.8 bits (133), Expect = 2e-07
Identities = 74/344 (21%), Positives = 134/344 (38%), Gaps = 46/344 (13%)
Query: 354 PRADNPSPNLMPASAQAQNAQRALAGVVLPSQGP---GGASELSSAHQLQQIAAKQKREQ 410
PR+ + SP L P S + A AG + P G + + + + K+K+++
Sbjct: 362 PRSASASP-LTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDK 420
Query: 411 MLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSV 470
+N ++ + + Q PASP + T S+L
Sbjct: 421 ERENEKEKSALARERSLKKRQSL---------------PASPRARLSASTASELSPKSKA 465
Query: 471 NKSSP-----RPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADC 525
SSP RP P P + L +PPS +A+ +G V K ++
Sbjct: 466 RPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRG-TTASPKGRVRRKEEAK-----ESPS 519
Query: 526 GQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVP 585
G QSK S+E+ S P P P + PP +EQ P+ P
Sbjct: 520 AAGPEDKSQSK-----------RRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETP 568
Query: 586 VQAQATSVGTQPPAVS--VASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQ 643
A +V T PPA + V S + ++ ++ + + +Q++RE+Q++ LQ
Sbjct: 569 TDA---AVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQA 625
Query: 644 QQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQ 687
++ + ++ LA + + + +R + Q+ + + +Q Q
Sbjct: 626 ERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQ 669
Score = 37.4 bits (85), Expect = 0.072
Identities = 92/455 (20%), Positives = 162/455 (35%), Gaps = 85/455 (18%)
Query: 562 PKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHN--------SSPYLS 613
P P M R PP + PS V A + S T+ H + YL+
Sbjct: 96 PTPPAMGPRDARPPRRSSQPSPTAVPA-SDSPPTKQEVKKAGERHKLAKERREERAKYLA 154
Query: 614 SQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQH-LLAEQEKQQFQRHLTRPPPQ 672
+++ + K+ + ++KQ +++++ L++Q+ Q+ L E+++Q+ +++ R
Sbjct: 155 AKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAA 214
Query: 673 YQ---DPTQGSFPQQVGQFTGS-SAAVPGMNTLG-------------------------- 702
Q T QQ + G+ + PG T G
Sbjct: 215 IQRSVKKTWAEIRQQRWSWAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSS 274
Query: 703 ------PSNSSCPRVFPQAGNLMP--MGP------GHASVSSLPTNSGQQDRGVAQFPGS 748
PS + ++ +++ M P S +LP N Q RG PG
Sbjct: 275 ATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCD--PG- 331
Query: 749 QNMPQSSLYGMASGITQIVAQPPPQATNGHAHI---PRQTNVGQNTSVSAAYGQNSLGSS 805
+ +G A + P P T+ A + PR + T S + +
Sbjct: 332 ----RGPTWGRAG--ASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPA 385
Query: 806 GLSQQHNKGTLNPGLTKPPV---PRVSPAMGGQNSSWQHQGMPNLSG----------QTP 852
G + K N G + PV P SP + + + S Q+
Sbjct: 386 GERGERRKP--NAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSL 443
Query: 853 GNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRT 912
S + +A+++ + ++ + SSP S +RP +P S G LPP R
Sbjct: 444 PASPRARLSASTASELSPKSKARPSSPSTSW---HRPASPCPSPGP-GHTLPPKPPSPRG 499
Query: 913 SAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPAS 947
+ +P ++ S AGPE + S+ AS
Sbjct: 500 TTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRAS 534
Score = 32.3 bits (72), Expect = 2.3
Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 15/132 (11%)
Query: 818 PGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMS 877
PG T PP P P+ G +S + G+ +A+ + Q+ + S
Sbjct: 486 PGHTLPPKP---PSPRGTTASPK--------GRVRRKEEAKESPSAAGPEDKSQSKRRAS 534
Query: 878 SPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPE 937
+ + S A P +P S A + PP Q P A T+P P ++P+ P
Sbjct: 535 NEKESAA----PASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPM 590
Query: 938 LGAFSQSPASQM 949
G + A+++
Sbjct: 591 AGTTDREEATRL 602
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 55.5 bits (132), Expect = 3e-07
Identities = 146/646 (22%), Positives = 211/646 (32%), Gaps = 145/646 (22%)
Query: 352 GQPRADNPSPNLMPASAQAQNAQ------RALAGVVLPSQG------PGGASELSSAHQL 399
G A +PS +PA +A +Q R +A V+ +QG P A+E S H+
Sbjct: 25 GASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRK 84
Query: 400 QQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDF 459
Q++ + +Q + P PA PG +S + T S +P SPS+
Sbjct: 85 QELDSSHPPKQSGRPPDPGRPAQ-PG-LSKSRTTDTFRSEQKLP-----GRSPSTISLKE 137
Query: 460 TNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLS 519
+ S+ + +KSS PG +L S VN LS +S N+ + D + S
Sbjct: 138 SKSRTDLKEE-HKSSMMPG--FL--SEVNALSAV-------SSVVNKFNPFDLISDSEAS 185
Query: 520 HYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQ 579
+ Q Q KP + + PP Q+Q
Sbjct: 186 QEETTKKQKVVQKEQGKPEGI-------------------------------IKPPLQQQ 214
Query: 580 NPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQK 639
P +P Q Q P + +SSQQ + + Q K
Sbjct: 215 PPKPIPKQ--------QGPGRDPLQQDGTPKSISSQQPEKI----------KSQPPGTGK 256
Query: 640 HLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMN 699
+Q + H K QR +RP + D +G + P +
Sbjct: 257 PIQGPTQTPQTDHA-----KLPLQRDASRPQTKQADIVRGE------------SVKPSL- 298
Query: 700 TLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGV----AQFPGSQNMPQSS 755
PS S P P G PGH P Q G+ AQ PG+ P
Sbjct: 299 ---PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 756 LYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGT 815
G T+ AQP G A P Q + S G L+Q
Sbjct: 356 -----PGTTKPPAQPL-----GPAKPPAQQTGSEKPS------SEQPGPKALAQP----- 394
Query: 816 LNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLK 875
PG+ K P + PA Q G P Q PG + + + +QQ K
Sbjct: 395 --PGVGKTPAQQPGPA----KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448
Query: 876 MSSPQFS-------QAVPNRPMAPMSSAAAV-----GSLLPPVSAQQRTSAPAPAPPPTA 923
+ + Q Q P +P + + A G PP P+ P T
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK 508
Query: 924 PQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQE 969
P PG + P+ S P SQ G A Q P + + Q+
Sbjct: 509 PPPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Score = 48.1 bits (113), Expect = 4e-05
Identities = 76/344 (22%), Positives = 115/344 (33%), Gaps = 40/344 (11%)
Query: 278 KKDPESSGSATQTPLA--QDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVS 335
K P +G Q P Q + K A + + VR S + PS P+
Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307
Query: 336 TDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSS 395
+P +Q H QP P P+ AQ+ G V P P G ++ +
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQP--GTVKPPVQPPGTTKPPA 363
Query: 396 AHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSY 455
Q + + Q + + ++ P P ++ Q G + P P + P
Sbjct: 364 ----QPLGPAKPPAQQTGSEKPSSEQPGPKALA--QPPGVGKTPAQQPGPAKPPT----- 412
Query: 456 KQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNT 515
+Q T L P + + PG P+ + P Q + + S G T
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPG-----PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467
Query: 516 KPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPP 575
KP S G +KP PQQ KP + S PP
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPP-----PQQPG------------SAKPPSQQPGSTKPP 510
Query: 576 GQEQNPSSV-PVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQA 618
Q+ P+ P Q +T +Q P + S+ SP S QQ+
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Score = 39.3 bits (90), Expect = 0.019
Identities = 43/173 (24%), Positives = 71/173 (41%), Gaps = 12/173 (6%)
Query: 135 PGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADS 194
PG +KT +E SS P SP G SD +D + SS L ++K +
Sbjct: 1334 PGKEKTEKEDDKSDTSSSQ--QPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKG 1391
Query: 195 SLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSN-----LMPDLNLNEQ 249
+ S S P L K L+ + L + S+ + P+ +++
Sbjct: 1392 LKKDSFSQESSPSSPSDLAK-LESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQE 1450
Query: 250 EWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEF 302
+ + L E L ++ +E++K E EE+KD S P ++D K+EF
Sbjct: 1451 KTQSLSETLEITISEEEIK----ESQEERKDTFKKDSQQDIPSSKDHKEKSEF 1499
Score = 38.9 bits (89), Expect = 0.025
Identities = 53/203 (26%), Positives = 69/203 (33%), Gaps = 38/203 (18%)
Query: 304 PAAFEQEQLGSPQVRAGSAG----QTFLGPSSAPVSTDSPSLGGSQTLF--HTSGQPRAD 357
PA +Q+G+P+ A G GP+ PV P +Q TS Q
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 358 NPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQ 417
P+ +P A+ Q A P Q PG A S Q P
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKP--PPQQPGSAKPPS------------------QQPGS 506
Query: 418 ATPAPAPGQMSTWQQTGPSHSSLDVPY----PMEKPASPSSYKQDFTNSKLLMMPSVNKS 473
P P QQ GP+ S P P ++P S Q + +K S
Sbjct: 507 TKPPP--------QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Query: 474 SPRPGGPYLQPSHVNLLSHQPPS 496
S G LQP V+ + QPPS
Sbjct: 559 SQTGSGKPLQPPTVSPSAKQPPS 581
Score = 33.1 bits (74), Expect = 1.4
Identities = 32/159 (20%), Positives = 65/159 (40%), Gaps = 28/159 (17%)
Query: 551 SHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSS- 609
S ++ SL+ + M + P + + S + A + + GT P +VS + S
Sbjct: 1685 SQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSS 1744
Query: 610 --------------------PYL----SSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQ 645
P L S ++ + ++ +LL +Q+KQRE +Q QQ++
Sbjct: 1745 PSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQ---QQRK 1801
Query: 646 FLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQ 684
++ ++ + Q +R + PP P + + P +
Sbjct: 1802 SSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTE 1840
Score = 31.6 bits (70), Expect = 4.0
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 23/92 (25%)
Query: 621 MKQHQLLLDQQKQRE-----------QQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRP 669
MKQH LL Q+++R+ QQQ L+Q Q LQ+Q H QQ + R
Sbjct: 3263 MKQH-LLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLH-------QQLEEQKIRQ 3314
Query: 670 PPQYQ-DPTQGSFPQQVGQ---FTGSSAAVPG 697
QY DP+ + PQ + G AA+ G
Sbjct: 3315 IYQYNYDPSGTASPQTTTEQAILEGQYAALEG 3346
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 55.5 bits (132), Expect = 3e-07
Identities = 146/646 (22%), Positives = 211/646 (32%), Gaps = 145/646 (22%)
Query: 352 GQPRADNPSPNLMPASAQAQNAQ------RALAGVVLPSQG------PGGASELSSAHQL 399
G A +PS +PA +A +Q R +A V+ +QG P A+E S H+
Sbjct: 25 GASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRK 84
Query: 400 QQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDF 459
Q++ + +Q + P PA PG +S + T S +P SPS+
Sbjct: 85 QELDSSHPPKQSGRPPDPGRPAQ-PG-LSKSRTTDTFRSEQKLP-----GRSPSTISLKE 137
Query: 460 TNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLS 519
+ S+ + +KSS PG +L S VN LS +S N+ + D + S
Sbjct: 138 SKSRTDLKEE-HKSSMMPG--FL--SEVNALSAV-------SSVVNKFNPFDLISDSEAS 185
Query: 520 HYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQ 579
+ Q Q KP + + PP Q+Q
Sbjct: 186 QEETTKKQKVVQKEQGKPEGI-------------------------------IKPPLQQQ 214
Query: 580 NPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQK 639
P +P Q Q P + +SSQQ + + Q K
Sbjct: 215 PPKPIPKQ--------QGPGRDPLQQDGTPKSISSQQPEKI----------KSQPPGTGK 256
Query: 640 HLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMN 699
+Q + H K QR +RP + D +G + P +
Sbjct: 257 PIQGPTQTPQTDHA-----KLPLQRDASRPQTKQADIVRGE------------SVKPSL- 298
Query: 700 TLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGV----AQFPGSQNMPQSS 755
PS S P P G PGH P Q G+ AQ PG+ P
Sbjct: 299 ---PSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355
Query: 756 LYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGT 815
G T+ AQP G A P Q + S G L+Q
Sbjct: 356 -----PGTTKPPAQPL-----GPAKPPAQQTGSEKPS------SEQPGPKALAQP----- 394
Query: 816 LNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLK 875
PG+ K P + PA Q G P Q PG + + + +QQ K
Sbjct: 395 --PGVGKTPAQQPGPA----KPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGK 448
Query: 876 MSSPQFS-------QAVPNRPMAPMSSAAAV-----GSLLPPVSAQQRTSAPAPAPPPTA 923
+ + Q Q P +P + + A G PP P+ P T
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTK 508
Query: 924 PQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQAYPVRTAGQE 969
P PG + P+ S P SQ G A Q P + + Q+
Sbjct: 509 PPPQQPGPAKPSPQQPG-STKPPSQQPGSAKPSAQQPSPAKPSAQQ 553
Score = 48.1 bits (113), Expect = 4e-05
Identities = 76/344 (22%), Positives = 115/344 (33%), Gaps = 40/344 (11%)
Query: 278 KKDPESSGSATQTPLA--QDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVS 335
K P +G Q P Q + K A + + VR S + PS P+
Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307
Query: 336 TDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSS 395
+P +Q H QP P P+ AQ+ G V P P G ++ +
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQ--PSGLTKPLAQQP--GTVKPPVQPPGTTKPPA 363
Query: 396 AHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSY 455
Q + + Q + + ++ P P ++ Q G + P P + P
Sbjct: 364 ----QPLGPAKPPAQQTGSEKPSSEQPGPKALA--QPPGVGKTPAQQPGPAKPPT----- 412
Query: 456 KQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNT 515
+Q T L P + + PG P+ + P Q + + S G T
Sbjct: 413 QQVGTPKPLAQQPGLQSPAKAPG-----PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT 467
Query: 516 KPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPP 575
KP S G +KP PQQ KP + S PP
Sbjct: 468 KPPSQLPGPAKPPPQQPGPAKPP-----PQQPG------------SAKPPSQQPGSTKPP 510
Query: 576 GQEQNPSSV-PVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQA 618
Q+ P+ P Q +T +Q P + S+ SP S QQ+
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQS 554
Score = 39.3 bits (90), Expect = 0.019
Identities = 43/173 (24%), Positives = 71/173 (41%), Gaps = 12/173 (6%)
Query: 135 PGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADS 194
PG +KT +E SS P SP G SD +D + SS L ++K +
Sbjct: 1334 PGKEKTEKEDDKSDTSSSQ--QPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKG 1391
Query: 195 SLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSN-----LMPDLNLNEQ 249
+ S S P L K L+ + L + S+ + P+ +++
Sbjct: 1392 LKKDSFSQESSPSSPSDLAK-LESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQE 1450
Query: 250 EWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKTEF 302
+ + L E L ++ +E++K E EE+KD S P ++D K+EF
Sbjct: 1451 KTQSLSETLEITISEEEIK----ESQEERKDTFKKDSQQDIPSSKDHKEKSEF 1499
Score = 38.9 bits (89), Expect = 0.025
Identities = 53/203 (26%), Positives = 69/203 (33%), Gaps = 38/203 (18%)
Query: 304 PAAFEQEQLGSPQVRAGSAG----QTFLGPSSAPVSTDSPSLGGSQTLF--HTSGQPRAD 357
PA +Q+G+P+ A G GP+ PV P +Q TS Q
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGP 466
Query: 358 NPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQ 417
P+ +P A+ Q A P Q PG A S Q P
Sbjct: 467 TKPPSQLPGPAKPPPQQPGPAKP--PPQQPGSAKPPS------------------QQPGS 506
Query: 418 ATPAPAPGQMSTWQQTGPSHSSLDVPY----PMEKPASPSSYKQDFTNSKLLMMPSVNKS 473
P P QQ GP+ S P P ++P S Q + +K S
Sbjct: 507 TKPPP--------QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Query: 474 SPRPGGPYLQPSHVNLLSHQPPS 496
S G LQP V+ + QPPS
Sbjct: 559 SQTGSGKPLQPPTVSPSAKQPPS 581
Score = 33.1 bits (74), Expect = 1.4
Identities = 32/159 (20%), Positives = 65/159 (40%), Gaps = 28/159 (17%)
Query: 551 SHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSS- 609
S ++ SL+ + M + P + + S + A + + GT P +VS + S
Sbjct: 1685 SQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSS 1744
Query: 610 --------------------PYL----SSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQ 645
P L S ++ + ++ +LL +Q+KQRE +Q QQ++
Sbjct: 1745 PSHKKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQ---QQRK 1801
Query: 646 FLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQ 684
++ ++ + Q +R + PP P + + P +
Sbjct: 1802 SSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTE 1840
Score = 31.6 bits (70), Expect = 4.0
Identities = 31/92 (33%), Positives = 42/92 (45%), Gaps = 23/92 (25%)
Query: 621 MKQHQLLLDQQKQRE-----------QQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRP 669
MKQH LL Q+++R+ QQQ L+Q Q LQ+Q H QQ + R
Sbjct: 3263 MKQH-LLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLH-------QQLEEQKIRQ 3314
Query: 670 PPQYQ-DPTQGSFPQQVGQ---FTGSSAAVPG 697
QY DP+ + PQ + G AA+ G
Sbjct: 3315 IYQYNYDPSGTASPQTTTEQAILEGQYAALEG 3346
>gi|27886520 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 55.5 bits (132), Expect = 3e-07
Identities = 143/631 (22%), Positives = 226/631 (35%), Gaps = 111/631 (17%)
Query: 283 SSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLG 342
++G+ Q+P+ Q +T +A + Q S+ G ++ +T +
Sbjct: 846 ANGNLQQSPVYQ----QTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATP 901
Query: 343 GSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGG----ASELSSAHQ 398
G+ T+F TS + QA+ Q ++ ++ Q G + SS
Sbjct: 902 GT-TMFQTSSSGDGEE-------TGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKS 953
Query: 399 LQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQD 458
+ + ++Q QQ + + QQ+ SHS + +P A + Q+
Sbjct: 954 MMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQS--SHSQAQLFHPQNPIADAQNLSQE 1011
Query: 459 FTNSKLLMMPS--VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSA--NNQGSVLDYGN 514
T L P+ V+ + +QP + Q + Q S+ +Q S + +
Sbjct: 1012 -TQGSLFHSPNPIVHSQTSTTSSEQMQPP---MFHSQSTIAVLQGSSVPQDQQSTNIFLS 1067
Query: 515 TKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVP 574
P+++ + + ++ A A P +S + NS F+ P
Sbjct: 1068 QSPMNNLQTNT--------VAQEAFFA-APNSISPLQSTSNS-------EQQAAFQQQAP 1111
Query: 575 PGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQR 634
Q P QAQ G P V++ S +P SQQ QH ++ Q
Sbjct: 1112 ISHIQTPMLSQEQAQPPQQGLFQPQVALGSLP-PNPMPQSQQGTMFQSQHSIVAMQSNSP 1170
Query: 635 EQQQKHLQQQQFLQRQQH----LLAEQEKQQFQRHLTRPPPQY-----QDP-------TQ 678
Q+Q+ QQQQ Q+QQ L + Q +PPP Q+P Q
Sbjct: 1171 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1230
Query: 679 GSFPQQVG-----------QFTGSSAAVPGMNTLGPSNS---------SCPRVFPQAGN- 717
F QQ QF S + V + GP+ S S P++ G+
Sbjct: 1231 SIFHQQSNMAPMNQEQQPMQFQ-SQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1289
Query: 718 -----LMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMAS---GITQIVAQ 769
+ + AS+S+L T+ QQD M QS LY + GI +
Sbjct: 1290 SSQEQQVTLFLSPASMSALQTSINQQD-----------MQQSPLYSPQNNMPGIQGATSS 1338
Query: 770 PPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVS 829
P PQAT H N QN+ S+ Q + G Q+N L LT P
Sbjct: 1339 PQPQATLFHNTAGGTMNQLQNSPGSS---QQTSGMFLFGIQNNCSQL---LTSGPATLPD 1392
Query: 830 PAMG-GQNSSWQHQGMPN----LSGQTPGNS 855
M Q Q++G P LS Q P NS
Sbjct: 1393 QLMAISQPGQPQNEGQPPVTTLLSQQMPENS 1423
Score = 37.7 bits (86), Expect = 0.055
Identities = 147/672 (21%), Positives = 238/672 (35%), Gaps = 116/672 (17%)
Query: 273 EDFEEKKDPESSGSATQTPLAQDINIKTEFS----PAAFEQEQLGSPQVRAGSAGQTFLG 328
+ F DP ++G A ++N+K E S P +FE E + + + + + +
Sbjct: 461 QPFTYTPDPAAAG-------ALNVNVKKEISSPARPCSFE-EAMKAMKTTGCNLDKVNII 512
Query: 329 PSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPG 388
P++ S+ S+ + T + A+ S + + + Q+ L + + G G
Sbjct: 513 PNALMTPLIPSSMIKSEDV--TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA-GNG 569
Query: 389 GASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHS-SLDVPYPME 447
S SS+H + +Q+ + NP+ T Q + T P+ S S +P
Sbjct: 570 SFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQT--QDISQPGTFPAVSASSQLPNSDA 627
Query: 448 KPASPSSYKQDFTNSKLLMMPS---VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSAN 504
+ ++ T S+ ++ VN S Q S + + ++ N
Sbjct: 628 LLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFP 687
Query: 505 NQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKP 564
+ SV NT + +A GS SG S L QQ+ + +S+ P
Sbjct: 688 SPNSVSQLQNT--IQQLQAGSFTGSTASGSSGSV---DLVQQVLEAQQQLSSVLFSAPD- 741
Query: 565 GNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASS--HNSSPYLSSQQQAAVMK 622
GN QEQ + + Q G P S H L + +V
Sbjct: 742 GNENV-------QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHP 794
Query: 623 QHQ-LLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSF 681
Q + L +QQ+Q++QQQ+ ++ + + Q Q Q L F
Sbjct: 795 QSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSEL--------------F 840
Query: 682 PQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRG 741
P S+A+ G P V+ Q ++M S+L TN Q
Sbjct: 841 P--------STASANGNLQQSP-------VYQQTSHMM---------SALSTNEDMQ--- 873
Query: 742 VAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNS 801
Q + P S ++ TQ VA P + G+ T A QNS
Sbjct: 874 -MQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQ-----TSSSGDGEETGTQAKQIQNS 927
Query: 802 LGSSGLSQQHNKGTLNPGLTKPPVPRVSPA---MGGQNSSWQHQGMPNLSGQTPGNSNVS 858
+ + + QH+ G +P V S M QNS Q QG GN +S
Sbjct: 928 VFQTMVQMQHS------GDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQ---QGNEMMS 978
Query: 859 PFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAV-----GSLL----PPVSAQ 909
S +QQ +H SQA P P++ A + GSL P V +Q
Sbjct: 979 ---LQSGNFLQQSSH--------SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQ 1027
Query: 910 QRTSAPAPAPPP 921
T++ PP
Sbjct: 1028 TSTTSSEQMQPP 1039
>gi|5729945 nuclear factor of activated T-cells 5 isoform c [Homo
sapiens]
Length = 1531
Score = 55.5 bits (132), Expect = 3e-07
Identities = 143/631 (22%), Positives = 226/631 (35%), Gaps = 111/631 (17%)
Query: 283 SSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLG 342
++G+ Q+P+ Q +T +A + Q S+ G ++ +T +
Sbjct: 922 ANGNLQQSPVYQ----QTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATP 977
Query: 343 GSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGG----ASELSSAHQ 398
G+ T+F TS + QA+ Q ++ ++ Q G + SS
Sbjct: 978 GT-TMFQTSSSGDGEE-------TGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKS 1029
Query: 399 LQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQD 458
+ + ++Q QQ + + QQ+ SHS + +P A + Q+
Sbjct: 1030 MMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQS--SHSQAQLFHPQNPIADAQNLSQE 1087
Query: 459 FTNSKLLMMPS--VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSA--NNQGSVLDYGN 514
T L P+ V+ + +QP + Q + Q S+ +Q S + +
Sbjct: 1088 -TQGSLFHSPNPIVHSQTSTTSSEQMQPP---MFHSQSTIAVLQGSSVPQDQQSTNIFLS 1143
Query: 515 TKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVP 574
P+++ + + ++ A A P +S + NS F+ P
Sbjct: 1144 QSPMNNLQTNT--------VAQEAFFA-APNSISPLQSTSNS-------EQQAAFQQQAP 1187
Query: 575 PGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQR 634
Q P QAQ G P V++ S +P SQQ QH ++ Q
Sbjct: 1188 ISHIQTPMLSQEQAQPPQQGLFQPQVALGSLP-PNPMPQSQQGTMFQSQHSIVAMQSNSP 1246
Query: 635 EQQQKHLQQQQFLQRQQH----LLAEQEKQQFQRHLTRPPPQY-----QDP-------TQ 678
Q+Q+ QQQQ Q+QQ L + Q +PPP Q+P Q
Sbjct: 1247 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1306
Query: 679 GSFPQQVG-----------QFTGSSAAVPGMNTLGPSNS---------SCPRVFPQAGN- 717
F QQ QF S + V + GP+ S S P++ G+
Sbjct: 1307 SIFHQQSNMAPMNQEQQPMQFQ-SQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1365
Query: 718 -----LMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMAS---GITQIVAQ 769
+ + AS+S+L T+ QQD M QS LY + GI +
Sbjct: 1366 SSQEQQVTLFLSPASMSALQTSINQQD-----------MQQSPLYSPQNNMPGIQGATSS 1414
Query: 770 PPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVS 829
P PQAT H N QN+ S+ Q + G Q+N L LT P
Sbjct: 1415 PQPQATLFHNTAGGTMNQLQNSPGSS---QQTSGMFLFGIQNNCSQL---LTSGPATLPD 1468
Query: 830 PAMG-GQNSSWQHQGMPN----LSGQTPGNS 855
M Q Q++G P LS Q P NS
Sbjct: 1469 QLMAISQPGQPQNEGQPPVTTLLSQQMPENS 1499
Score = 37.7 bits (86), Expect = 0.055
Identities = 147/672 (21%), Positives = 238/672 (35%), Gaps = 116/672 (17%)
Query: 273 EDFEEKKDPESSGSATQTPLAQDINIKTEFS----PAAFEQEQLGSPQVRAGSAGQTFLG 328
+ F DP ++G A ++N+K E S P +FE E + + + + + +
Sbjct: 537 QPFTYTPDPAAAG-------ALNVNVKKEISSPARPCSFE-EAMKAMKTTGCNLDKVNII 588
Query: 329 PSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPG 388
P++ S+ S+ + T + A+ S + + + Q+ L + + G G
Sbjct: 589 PNALMTPLIPSSMIKSEDV--TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA-GNG 645
Query: 389 GASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHS-SLDVPYPME 447
S SS+H + +Q+ + NP+ T Q + T P+ S S +P
Sbjct: 646 SFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQT--QDISQPGTFPAVSASSQLPNSDA 703
Query: 448 KPASPSSYKQDFTNSKLLMMPS---VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSAN 504
+ ++ T S+ ++ VN S Q S + + ++ N
Sbjct: 704 LLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFP 763
Query: 505 NQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKP 564
+ SV NT + +A GS SG S L QQ+ + +S+ P
Sbjct: 764 SPNSVSQLQNT--IQQLQAGSFTGSTASGSSGSV---DLVQQVLEAQQQLSSVLFSAPD- 817
Query: 565 GNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASS--HNSSPYLSSQQQAAVMK 622
GN QEQ + + Q G P S H L + +V
Sbjct: 818 GNENV-------QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHP 870
Query: 623 QHQ-LLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSF 681
Q + L +QQ+Q++QQQ+ ++ + + Q Q Q L F
Sbjct: 871 QSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSEL--------------F 916
Query: 682 PQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRG 741
P S+A+ G P V+ Q ++M S+L TN Q
Sbjct: 917 P--------STASANGNLQQSP-------VYQQTSHMM---------SALSTNEDMQ--- 949
Query: 742 VAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNS 801
Q + P S ++ TQ VA P + G+ T A QNS
Sbjct: 950 -MQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQ-----TSSSGDGEETGTQAKQIQNS 1003
Query: 802 LGSSGLSQQHNKGTLNPGLTKPPVPRVSPA---MGGQNSSWQHQGMPNLSGQTPGNSNVS 858
+ + + QH+ G +P V S M QNS Q QG GN +S
Sbjct: 1004 VFQTMVQMQHS------GDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQ---QGNEMMS 1054
Query: 859 PFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAV-----GSLL----PPVSAQ 909
S +QQ +H SQA P P++ A + GSL P V +Q
Sbjct: 1055 ---LQSGNFLQQSSH--------SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQ 1103
Query: 910 QRTSAPAPAPPP 921
T++ PP
Sbjct: 1104 TSTTSSEQMQPP 1115
>gi|164419746 nuclear factor of activated T-cells 5 isoform d [Homo
sapiens]
Length = 1548
Score = 55.5 bits (132), Expect = 3e-07
Identities = 143/631 (22%), Positives = 226/631 (35%), Gaps = 111/631 (17%)
Query: 283 SSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLG 342
++G+ Q+P+ Q +T +A + Q S+ G ++ +T +
Sbjct: 939 ANGNLQQSPVYQ----QTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATP 994
Query: 343 GSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGG----ASELSSAHQ 398
G+ T+F TS + QA+ Q ++ ++ Q G + SS
Sbjct: 995 GT-TMFQTSSSGDGEE-------TGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKS 1046
Query: 399 LQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQD 458
+ + ++Q QQ + + QQ+ SHS + +P A + Q+
Sbjct: 1047 MMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQS--SHSQAQLFHPQNPIADAQNLSQE 1104
Query: 459 FTNSKLLMMPS--VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSA--NNQGSVLDYGN 514
T L P+ V+ + +QP + Q + Q S+ +Q S + +
Sbjct: 1105 -TQGSLFHSPNPIVHSQTSTTSSEQMQPP---MFHSQSTIAVLQGSSVPQDQQSTNIFLS 1160
Query: 515 TKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVP 574
P+++ + + ++ A A P +S + NS F+ P
Sbjct: 1161 QSPMNNLQTNT--------VAQEAFFA-APNSISPLQSTSNS-------EQQAAFQQQAP 1204
Query: 575 PGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQR 634
Q P QAQ G P V++ S +P SQQ QH ++ Q
Sbjct: 1205 ISHIQTPMLSQEQAQPPQQGLFQPQVALGSLP-PNPMPQSQQGTMFQSQHSIVAMQSNSP 1263
Query: 635 EQQQKHLQQQQFLQRQQH----LLAEQEKQQFQRHLTRPPPQY-----QDP-------TQ 678
Q+Q+ QQQQ Q+QQ L + Q +PPP Q+P Q
Sbjct: 1264 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1323
Query: 679 GSFPQQVG-----------QFTGSSAAVPGMNTLGPSNS---------SCPRVFPQAGN- 717
F QQ QF S + V + GP+ S S P++ G+
Sbjct: 1324 SIFHQQSNMAPMNQEQQPMQFQ-SQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1382
Query: 718 -----LMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMAS---GITQIVAQ 769
+ + AS+S+L T+ QQD M QS LY + GI +
Sbjct: 1383 SSQEQQVTLFLSPASMSALQTSINQQD-----------MQQSPLYSPQNNMPGIQGATSS 1431
Query: 770 PPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVS 829
P PQAT H N QN+ S+ Q + G Q+N L LT P
Sbjct: 1432 PQPQATLFHNTAGGTMNQLQNSPGSS---QQTSGMFLFGIQNNCSQL---LTSGPATLPD 1485
Query: 830 PAMG-GQNSSWQHQGMPN----LSGQTPGNS 855
M Q Q++G P LS Q P NS
Sbjct: 1486 QLMAISQPGQPQNEGQPPVTTLLSQQMPENS 1516
Score = 36.2 bits (82), Expect = 0.16
Identities = 143/652 (21%), Positives = 231/652 (35%), Gaps = 109/652 (16%)
Query: 293 AQDINIKTEFS----PAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLF 348
A ++N+K E S P +FE E + + + + + + P++ S+ S+ +
Sbjct: 567 ALNVNVKKEISSPARPCSFE-EAMKAMKTTGCNLDKVNIIPNALMTPLIPSSMIKSEDV- 624
Query: 349 HTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKR 408
T + A+ S + + + Q+ L + + G G S SS+H + +Q+
Sbjct: 625 -TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA-GNGSFSSPSSSHLPSENEKQQQI 682
Query: 409 EQMLQNPQQATPAPAPGQMSTWQQTGPSHS-SLDVPYPMEKPASPSSYKQDFTNSKLLMM 467
+ NP+ T Q + T P+ S S +P + ++ T S+ ++
Sbjct: 683 QPKAYNPETLTTIQT--QDISQPGTFPAVSASSQLPNSDALLQQATQFQTRETQSREILQ 740
Query: 468 PS---VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKAD 524
VN S Q S + + ++ N + SV NT + +A
Sbjct: 741 SDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFPSPNSVSQLQNT--IQQLQAG 798
Query: 525 CGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSV 584
GS SG S L QQ+ + +S+ P GN QEQ + +
Sbjct: 799 SFTGSTASGSSGSV---DLVQQVLEAQQQLSSVLFSAPD-GNENV-------QEQLSADI 847
Query: 585 PVQAQATSVGTQPPAVSVASS--HNSSPYLSSQQQAAVMKQHQ-LLLDQQKQREQQQKHL 641
Q G P S H L + +V Q + L +QQ+Q++QQQ+ +
Sbjct: 848 FQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHPQSENTLSNQQQQQQQQQQVM 907
Query: 642 QQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTL 701
+ + + Q Q Q L FP S+A+ G
Sbjct: 908 ESSAAMVMEMQQSICQAAAQIQSEL--------------FP--------STASANGNLQQ 945
Query: 702 GPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMAS 761
P V+ Q ++M S+L TN Q Q + P S ++
Sbjct: 946 SP-------VYQQTSHMM---------SALSTNEDMQ----MQCELFSSPPAVSGNETST 985
Query: 762 GITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLT 821
TQ VA P + G+ T A QNS+ + + QH+ G
Sbjct: 986 TTTQQVATPGTTMFQ-----TSSSGDGEETGTQAKQIQNSVFQTMVQMQHS------GDN 1034
Query: 822 KPPVPRVSPA---MGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSS 878
+P V S M QNS Q QG GN +S S +QQ +H
Sbjct: 1035 QPQVNLFSSTKSMMSVQNSGTQQQGNGLFQ---QGNEMMS---LQSGNFLQQSSH----- 1083
Query: 879 PQFSQAVPNRPMAPMSSAAAV-----GSLL----PPVSAQQRTSAPAPAPPP 921
SQA P P++ A + GSL P V +Q T++ PP
Sbjct: 1084 ---SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQTSTTSSEQMQPP 1132
>gi|164419744 nuclear factor of activated T-cells 5 isoform b [Homo
sapiens]
Length = 1549
Score = 55.5 bits (132), Expect = 3e-07
Identities = 143/631 (22%), Positives = 226/631 (35%), Gaps = 111/631 (17%)
Query: 283 SSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLG 342
++G+ Q+P+ Q +T +A + Q S+ G ++ +T +
Sbjct: 940 ANGNLQQSPVYQ----QTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATP 995
Query: 343 GSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGG----ASELSSAHQ 398
G+ T+F TS + QA+ Q ++ ++ Q G + SS
Sbjct: 996 GT-TMFQTSSSGDGEE-------TGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKS 1047
Query: 399 LQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQD 458
+ + ++Q QQ + + QQ+ SHS + +P A + Q+
Sbjct: 1048 MMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQS--SHSQAQLFHPQNPIADAQNLSQE 1105
Query: 459 FTNSKLLMMPS--VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSA--NNQGSVLDYGN 514
T L P+ V+ + +QP + Q + Q S+ +Q S + +
Sbjct: 1106 -TQGSLFHSPNPIVHSQTSTTSSEQMQPP---MFHSQSTIAVLQGSSVPQDQQSTNIFLS 1161
Query: 515 TKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVP 574
P+++ + + ++ A A P +S + NS F+ P
Sbjct: 1162 QSPMNNLQTNT--------VAQEAFFA-APNSISPLQSTSNS-------EQQAAFQQQAP 1205
Query: 575 PGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQR 634
Q P QAQ G P V++ S +P SQQ QH ++ Q
Sbjct: 1206 ISHIQTPMLSQEQAQPPQQGLFQPQVALGSLP-PNPMPQSQQGTMFQSQHSIVAMQSNSP 1264
Query: 635 EQQQKHLQQQQFLQRQQH----LLAEQEKQQFQRHLTRPPPQY-----QDP-------TQ 678
Q+Q+ QQQQ Q+QQ L + Q +PPP Q+P Q
Sbjct: 1265 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1324
Query: 679 GSFPQQVG-----------QFTGSSAAVPGMNTLGPSNS---------SCPRVFPQAGN- 717
F QQ QF S + V + GP+ S S P++ G+
Sbjct: 1325 SIFHQQSNMAPMNQEQQPMQFQ-SQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1383
Query: 718 -----LMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMAS---GITQIVAQ 769
+ + AS+S+L T+ QQD M QS LY + GI +
Sbjct: 1384 SSQEQQVTLFLSPASMSALQTSINQQD-----------MQQSPLYSPQNNMPGIQGATSS 1432
Query: 770 PPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVS 829
P PQAT H N QN+ S+ Q + G Q+N L LT P
Sbjct: 1433 PQPQATLFHNTAGGTMNQLQNSPGSS---QQTSGMFLFGIQNNCSQL---LTSGPATLPD 1486
Query: 830 PAMG-GQNSSWQHQGMPN----LSGQTPGNS 855
M Q Q++G P LS Q P NS
Sbjct: 1487 QLMAISQPGQPQNEGQPPVTTLLSQQMPENS 1517
Score = 37.7 bits (86), Expect = 0.055
Identities = 147/672 (21%), Positives = 238/672 (35%), Gaps = 116/672 (17%)
Query: 273 EDFEEKKDPESSGSATQTPLAQDINIKTEFS----PAAFEQEQLGSPQVRAGSAGQTFLG 328
+ F DP ++G A ++N+K E S P +FE E + + + + + +
Sbjct: 555 QPFTYTPDPAAAG-------ALNVNVKKEISSPARPCSFE-EAMKAMKTTGCNLDKVNII 606
Query: 329 PSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPG 388
P++ S+ S+ + T + A+ S + + + Q+ L + + G G
Sbjct: 607 PNALMTPLIPSSMIKSEDV--TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA-GNG 663
Query: 389 GASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHS-SLDVPYPME 447
S SS+H + +Q+ + NP+ T Q + T P+ S S +P
Sbjct: 664 SFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQT--QDISQPGTFPAVSASSQLPNSDA 721
Query: 448 KPASPSSYKQDFTNSKLLMMPS---VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSAN 504
+ ++ T S+ ++ VN S Q S + + ++ N
Sbjct: 722 LLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFP 781
Query: 505 NQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKP 564
+ SV NT + +A GS SG S L QQ+ + +S+ P
Sbjct: 782 SPNSVSQLQNT--IQQLQAGSFTGSTASGSSGSV---DLVQQVLEAQQQLSSVLFSAPD- 835
Query: 565 GNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASS--HNSSPYLSSQQQAAVMK 622
GN QEQ + + Q G P S H L + +V
Sbjct: 836 GNENV-------QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHP 888
Query: 623 QHQ-LLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSF 681
Q + L +QQ+Q++QQQ+ ++ + + Q Q Q L F
Sbjct: 889 QSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSEL--------------F 934
Query: 682 PQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRG 741
P S+A+ G P V+ Q ++M S+L TN Q
Sbjct: 935 P--------STASANGNLQQSP-------VYQQTSHMM---------SALSTNEDMQ--- 967
Query: 742 VAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNS 801
Q + P S ++ TQ VA P + G+ T A QNS
Sbjct: 968 -MQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQ-----TSSSGDGEETGTQAKQIQNS 1021
Query: 802 LGSSGLSQQHNKGTLNPGLTKPPVPRVSPA---MGGQNSSWQHQGMPNLSGQTPGNSNVS 858
+ + + QH+ G +P V S M QNS Q QG GN +S
Sbjct: 1022 VFQTMVQMQHS------GDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQ---QGNEMMS 1072
Query: 859 PFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAV-----GSLL----PPVSAQ 909
S +QQ +H SQA P P++ A + GSL P V +Q
Sbjct: 1073 ---LQSGNFLQQSSH--------SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQ 1121
Query: 910 QRTSAPAPAPPP 921
T++ PP
Sbjct: 1122 TSTTSSEQMQPP 1133
>gi|27886524 nuclear factor of activated T-cells 5 isoform a [Homo
sapiens]
Length = 1455
Score = 55.5 bits (132), Expect = 3e-07
Identities = 143/631 (22%), Positives = 226/631 (35%), Gaps = 111/631 (17%)
Query: 283 SSGSATQTPLAQDINIKTEFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLG 342
++G+ Q+P+ Q +T +A + Q S+ G ++ +T +
Sbjct: 846 ANGNLQQSPVYQ----QTSHMMSALSTNEDMQMQCELFSSPPAVSGNETSTTTTQQVATP 901
Query: 343 GSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGG----ASELSSAHQ 398
G+ T+F TS + QA+ Q ++ ++ Q G + SS
Sbjct: 902 GT-TMFQTSSSGDGEE-------TGTQAKQIQNSVFQTMVQMQHSGDNQPQVNLFSSTKS 953
Query: 399 LQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQD 458
+ + ++Q QQ + + QQ+ SHS + +P A + Q+
Sbjct: 954 MMSVQNSGTQQQGNGLFQQGNEMMSLQSGNFLQQS--SHSQAQLFHPQNPIADAQNLSQE 1011
Query: 459 FTNSKLLMMPS--VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSA--NNQGSVLDYGN 514
T L P+ V+ + +QP + Q + Q S+ +Q S + +
Sbjct: 1012 -TQGSLFHSPNPIVHSQTSTTSSEQMQPP---MFHSQSTIAVLQGSSVPQDQQSTNIFLS 1067
Query: 515 TKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVP 574
P+++ + + ++ A A P +S + NS F+ P
Sbjct: 1068 QSPMNNLQTNT--------VAQEAFFA-APNSISPLQSTSNS-------EQQAAFQQQAP 1111
Query: 575 PGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQR 634
Q P QAQ G P V++ S +P SQQ QH ++ Q
Sbjct: 1112 ISHIQTPMLSQEQAQPPQQGLFQPQVALGSLP-PNPMPQSQQGTMFQSQHSIVAMQSNSP 1170
Query: 635 EQQQKHLQQQQFLQRQQH----LLAEQEKQQFQRHLTRPPPQY-----QDP-------TQ 678
Q+Q+ QQQQ Q+QQ L + Q +PPP Q+P Q
Sbjct: 1171 SQEQQQQQQQQQQQQQQQQQSILFSNQNTMATMASPKQPPPNMIFNPNQNPMANQEQQNQ 1230
Query: 679 GSFPQQVG-----------QFTGSSAAVPGMNTLGPSNS---------SCPRVFPQAGN- 717
F QQ QF S + V + GP+ S S P++ G+
Sbjct: 1231 SIFHQQSNMAPMNQEQQPMQFQ-SQSTVSSLQNPGPTQSESSQTPLFHSSPQIQLVQGSP 1289
Query: 718 -----LMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMAS---GITQIVAQ 769
+ + AS+S+L T+ QQD M QS LY + GI +
Sbjct: 1290 SSQEQQVTLFLSPASMSALQTSINQQD-----------MQQSPLYSPQNNMPGIQGATSS 1338
Query: 770 PPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVS 829
P PQAT H N QN+ S+ Q + G Q+N L LT P
Sbjct: 1339 PQPQATLFHNTAGGTMNQLQNSPGSS---QQTSGMFLFGIQNNCSQL---LTSGPATLPD 1392
Query: 830 PAMG-GQNSSWQHQGMPN----LSGQTPGNS 855
M Q Q++G P LS Q P NS
Sbjct: 1393 QLMAISQPGQPQNEGQPPVTTLLSQQMPENS 1423
Score = 37.7 bits (86), Expect = 0.055
Identities = 147/672 (21%), Positives = 238/672 (35%), Gaps = 116/672 (17%)
Query: 273 EDFEEKKDPESSGSATQTPLAQDINIKTEFS----PAAFEQEQLGSPQVRAGSAGQTFLG 328
+ F DP ++G A ++N+K E S P +FE E + + + + + +
Sbjct: 461 QPFTYTPDPAAAG-------ALNVNVKKEISSPARPCSFE-EAMKAMKTTGCNLDKVNII 512
Query: 329 PSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPG 388
P++ S+ S+ + T + A+ S + + + Q+ L + + G G
Sbjct: 513 PNALMTPLIPSSMIKSEDV--TPMEVTAEKRSSTIFKTTKSVGSTQQTLENISNIA-GNG 569
Query: 389 GASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHS-SLDVPYPME 447
S SS+H + +Q+ + NP+ T Q + T P+ S S +P
Sbjct: 570 SFSSPSSSHLPSENEKQQQIQPKAYNPETLTTIQT--QDISQPGTFPAVSASSQLPNSDA 627
Query: 448 KPASPSSYKQDFTNSKLLMMPS---VNKSSPRPGGPYLQPSHVNLLSHQPPSNLNQNSAN 504
+ ++ T S+ ++ VN S Q S + + ++ N
Sbjct: 628 LLQQATQFQTRETQSREILQSDGTVVNLSQLTEASQQQQQSPLQEQAQTLQQQISSNIFP 687
Query: 505 NQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKP 564
+ SV NT + +A GS SG S L QQ+ + +S+ P
Sbjct: 688 SPNSVSQLQNT--IQQLQAGSFTGSTASGSSGSV---DLVQQVLEAQQQLSSVLFSAPD- 741
Query: 565 GNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASS--HNSSPYLSSQQQAAVMK 622
GN QEQ + + Q G P S H L + +V
Sbjct: 742 GNENV-------QEQLSADIFQQVSQIQSGVSPGMFSSTEPTVHTRPDNLLPGRAESVHP 794
Query: 623 QHQ-LLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSF 681
Q + L +QQ+Q++QQQ+ ++ + + Q Q Q L F
Sbjct: 795 QSENTLSNQQQQQQQQQQVMESSAAMVMEMQQSICQAAAQIQSEL--------------F 840
Query: 682 PQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRG 741
P S+A+ G P V+ Q ++M S+L TN Q
Sbjct: 841 P--------STASANGNLQQSP-------VYQQTSHMM---------SALSTNEDMQ--- 873
Query: 742 VAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNS 801
Q + P S ++ TQ VA P + G+ T A QNS
Sbjct: 874 -MQCELFSSPPAVSGNETSTTTTQQVATPGTTMFQ-----TSSSGDGEETGTQAKQIQNS 927
Query: 802 LGSSGLSQQHNKGTLNPGLTKPPVPRVSPA---MGGQNSSWQHQGMPNLSGQTPGNSNVS 858
+ + + QH+ G +P V S M QNS Q QG GN +S
Sbjct: 928 VFQTMVQMQHS------GDNQPQVNLFSSTKSMMSVQNSGTQQQGNGLFQ---QGNEMMS 978
Query: 859 PFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAV-----GSLL----PPVSAQ 909
S +QQ +H SQA P P++ A + GSL P V +Q
Sbjct: 979 ---LQSGNFLQQSSH--------SQAQLFHPQNPIADAQNLSQETQGSLFHSPNPIVHSQ 1027
Query: 910 QRTSAPAPAPPP 921
T++ PP
Sbjct: 1028 TSTTSSEQMQPP 1039
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 54.7 bits (130), Expect = 4e-07
Identities = 130/544 (23%), Positives = 185/544 (34%), Gaps = 112/544 (20%)
Query: 333 PVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNA---QRALAGVVLPSQGPGG 389
P ++ P G L QP P P Q Q+ +R +P G
Sbjct: 271 PGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPV---GL 327
Query: 390 ASELSSAHQLQQI---AAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPM 446
+ S H L Q A ++Q Q P Q P P PG + P+ +P P
Sbjct: 328 EPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPA-----LPRPQ 382
Query: 447 EKPA-SPSSYKQDFTNSKLLMMPS--------VNKSSPRPGGPYLQPSHVNLLSHQPPSN 497
+ A +PS QD M+PS +++ R PY +P V + H PP
Sbjct: 383 QGEAGTPSGGLQDGGP----MLPSQHAQFEYPIHRLENRSMHPYSEP--VFSMQHPPP-- 434
Query: 498 LNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGS-GQSKPALMAYLPQQLSHISHEQNS 556
Q + N + L + + P + PGS G + A + +H S
Sbjct: 435 --QQAPNQR---LQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPS 489
Query: 557 LFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQ 616
+ PG +P PP + PS P+Q H + + S QQ
Sbjct: 490 AY-----PG-LP-GEFTPPVPDSFPSGPPLQ------------------HPAPDHQSLQQ 524
Query: 617 QAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQ-- 674
Q Q Q QQ+Q++QQQ+ QQQQ ++ L+ +Q + Q+ R P Q
Sbjct: 525 Q-----QQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLG 579
Query: 675 ---DPTQGSFPQ--QVGQFTGSSAAVPGMNT----LGPSNSSCPRV----------FPQA 715
D QG VG + G +T LG P + P
Sbjct: 580 HPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPP 639
Query: 716 GNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQAT 775
G+L+P G S LP + G D +A P SG+ P
Sbjct: 640 GDLLPRRMGG---SGLPADCGPHDPSLAPPPPPG----------GSGVLFRGPLQEPMRM 686
Query: 776 NGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTK----PPVPRVSPA 831
G H+P + G SLG G Q G P PP + A
Sbjct: 687 PGEGHVPALPSPGLQFG-------GSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSA 739
Query: 832 MGGQ 835
+GGQ
Sbjct: 740 LGGQ 743
Score = 46.6 bits (109), Expect = 1e-04
Identities = 96/411 (23%), Positives = 134/411 (32%), Gaps = 83/411 (20%)
Query: 580 NPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQK 639
+PS Q + G Q P + P S+ +AA M L Q QQQ
Sbjct: 248 SPSDSEGQLPHYAAGRQVPG-------GAFPGASAMPRAAGMVG---LSKMHAQPPQQQP 297
Query: 640 HLQQQQFLQRQQH------------LLAEQEKQQFQRH-LTRPPPQYQDPTQGSFPQQVG 686
QQQ Q+QQH + E RH L +PP Q P Q PQQ
Sbjct: 298 QQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPP 357
Query: 687 QFTGSSAAVPGMNTLGPSNSSCPRVFPQ---------AGNLMPMGPGHASVSSLPTNSGQ 737
Q PG+ +SCP P+ +G L GP LP+ Q
Sbjct: 358 Q--QQPPPPPGLLV---RQNSCPPALPRPQQGEAGTPSGGLQDGGP------MLPSQHAQ 406
Query: 738 QDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATN---GHAHIPRQTNVGQ----- 789
+ + + S++ + + + PP QA N H P NV +
Sbjct: 407 FEYPI------HRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFD 460
Query: 790 ---NTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLT---KPPVPRVSPAMGGQNSSWQHQG 843
+ V N +G H + PGL PPVP P+
Sbjct: 461 FPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPS------------ 508
Query: 844 MPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLL 903
P L P + ++ QQQ + Q Q + +AA + +
Sbjct: 509 GPPLQHPAPDHQSLQQ-------QQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQM 561
Query: 904 PPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAG 954
+ QQR P A G GL GP +G +Q + GG G
Sbjct: 562 ASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGP-VGGLAQPNFEREGGSTG 611
>gi|162951884 R3H domain containing 2 [Homo sapiens]
Length = 976
Score = 54.7 bits (130), Expect = 4e-07
Identities = 102/427 (23%), Positives = 159/427 (37%), Gaps = 72/427 (16%)
Query: 548 SHISHEQNSLFLMKPKPGNMP-----FRSLVPPGQEQNP-SSVPVQAQATSVGTQPPA-- 599
S S + L ++P+P + RS+ PP + + S + + + S+G+
Sbjct: 311 SRQSSTDSELKSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSIGSSKGGSA 370
Query: 600 --VSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHL-------QQQQFLQRQ 650
+S +P + +Q ++ + L Q+Q++QQQ+ L QQQ L
Sbjct: 371 GRISRPGMALGAPEVCNQVTSSQSVRGLLPCTAQQQQQQQQQQLPALPPTPQQQPPLNNH 430
Query: 651 QHLLAEQEKQQF-QRHLTRPPPQ---------YQDPTQGSFPQQVGQFTGSSAAVPGMNT 700
A+ F Q L+R +Q P PQQ S+ +
Sbjct: 431 MISQADDLSNPFGQMSLSRQGSTEAADPSAALFQTPLISQHPQQTSFIMASTGQPLPTSN 490
Query: 701 LGPSNSSCP--RVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYG 758
S+ + P +V P G + P P VS P Q+P S + +
Sbjct: 491 YSTSSHAPPTQQVLPPQGYMQP--PQQIQVSYYPPG---------QYPNSNQQYRPLSHP 539
Query: 759 MASGITQIVAQPPPQATNGHAHIPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNP 818
+A + Q PQ + P N Q AAY G G+ Q N+G L+
Sbjct: 540 VAYSPQR--GQQLPQPSQQPGLQPMMPNQQQ-----AAYQ----GMIGVQQPQNQGLLSS 588
Query: 819 GLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVS-----PFTAASSFHMQQQAH 873
+ +MGGQ Q P S Q P S+ PF + Q
Sbjct: 589 QRS---------SMGGQMQGLVVQYTPLPSYQVPVGSDSQNVVQPPFQQPMLVPVSQSVQ 639
Query: 874 LKMSS---PQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQ-QRTSAPAPAPPPTAPQQGLP 929
+ + P + +P P ++ +VG L PP S Q Q +P+P PP PQQ
Sbjct: 640 GGLPAAGVPVYYSMIP--PAQQNGTSPSVGFLQPPGSEQYQMPQSPSPCSPPQMPQQ-YS 696
Query: 930 GLSPAGP 936
G+SP+GP
Sbjct: 697 GVSPSGP 703
Score = 31.6 bits (70), Expect = 4.0
Identities = 50/192 (26%), Positives = 78/192 (40%), Gaps = 22/192 (11%)
Query: 361 PNLMPASAQAQNAQRALAGV-----VLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNP 415
P L+P S Q A AGV ++P G S S LQ ++Q QM Q+P
Sbjct: 629 PMLVPVSQSVQGGLPA-AGVPVYYSMIPPAQQNGTSP--SVGFLQPPGSEQY--QMPQSP 683
Query: 416 QQATPAPAPGQMSTWQQTGPS--HSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKS 473
+P P Q S +GP L+VP + P +PS + +++ K S+++
Sbjct: 684 SPCSPPQMPQQYSGVSPSGPGVVVMQLNVPNGPQPPQNPSMVQ--WSHCKYY---SMDQR 738
Query: 474 SPRPG---GPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNT--KPLSHYKADCGQG 528
+PG P P +S P ++ Q+ A + + L T PL G
Sbjct: 739 GQKPGDLYSPDSSPQANTQMSSSPVTSPTQSPAPSPVTSLSSVCTGLSPLPVLTQFPRPG 798
Query: 529 SPGSGQSKPALM 540
P G + +L+
Sbjct: 799 GPAQGDGRYSLL 810
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 53.9 bits (128), Expect = 7e-07
Identities = 58/210 (27%), Positives = 84/210 (40%), Gaps = 35/210 (16%)
Query: 496 SNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQN 555
S++NQN + S LD G+ G+ S G S+ + + L Q
Sbjct: 13 SSMNQNGMSTLSSQLDAGSRD---------GRSS-GDTSSEVSTVELLHLQQQQALQAAR 62
Query: 556 SLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQA--QATSVGTQPPAVSVASSHNSSPY-- 611
L L + G +S +Q P VPV V T + SP
Sbjct: 63 QLLLQQQTSGLKSPKS----SDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSPQQL 118
Query: 612 --LSSQQQAAVMKQHQL---------------LLDQQKQREQQQKHLQQQQFLQRQQHLL 654
L QQQA +++Q QL L QQ+Q++QQQ+ QQQQ Q+QQ
Sbjct: 119 QALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178
Query: 655 AEQEKQQFQRHLTRPPPQYQDPTQGSFPQQ 684
+Q++QQ Q+ P Q ++ Q QQ
Sbjct: 179 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 208
Score = 38.9 bits (89), Expect = 0.025
Identities = 43/154 (27%), Positives = 61/154 (39%), Gaps = 24/154 (15%)
Query: 544 PQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVA 603
PQQL + +Q ++ L + + + QEQ + Q Q Q
Sbjct: 115 PQQLQALLQQQQAVMLQQQQ-----LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQ 169
Query: 604 SSHNSSPYLSSQQQAAVMKQHQ----LLLDQQKQREQQ----------QKHLQQQQFLQR 649
QQQ +Q Q +QQ+Q++QQ Q+ L Q Q LQ+
Sbjct: 170 QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 229
Query: 650 QQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQ 683
QQHLL+ Q Q ++ PP Q P Q S PQ
Sbjct: 230 QQHLLSLQR----QGLISIPPGQAALPVQ-SLPQ 258
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 53.9 bits (128), Expect = 7e-07
Identities = 62/228 (27%), Positives = 89/228 (39%), Gaps = 46/228 (20%)
Query: 496 SNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHE-- 553
S++NQN + S LD G+ S G S S L+ QQ + +
Sbjct: 13 SSMNQNGMSTLSSQLDAGSRDGRS-------SGDTSSEVSTVELLHLQQQQALQAARQLL 65
Query: 554 --QNSLFLMKPKPGNM--PFRSLVPP------------GQEQNPSSVPVQA--QATSVGT 595
Q + L PK + P + L+P G N +VPV V T
Sbjct: 66 LQQQTSGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVIT 125
Query: 596 QPPAVSVASSHNSSPY----LSSQQQAAVMKQHQL---------------LLDQQKQREQ 636
+ SP L QQQA +++Q QL L QQ+Q++Q
Sbjct: 126 PQQMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ 185
Query: 637 QQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQ 684
QQ+ QQQQ Q+QQ +Q++QQ Q+ P Q ++ Q QQ
Sbjct: 186 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 233
Score = 38.9 bits (89), Expect = 0.025
Identities = 43/154 (27%), Positives = 61/154 (39%), Gaps = 24/154 (15%)
Query: 544 PQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVA 603
PQQL + +Q ++ L + + + QEQ + Q Q Q
Sbjct: 140 PQQLQALLQQQQAVMLQQQQ-----LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQ 194
Query: 604 SSHNSSPYLSSQQQAAVMKQHQ----LLLDQQKQREQQ----------QKHLQQQQFLQR 649
QQQ +Q Q +QQ+Q++QQ Q+ L Q Q LQ+
Sbjct: 195 QQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ 254
Query: 650 QQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQ 683
QQHLL+ Q Q ++ PP Q P Q S PQ
Sbjct: 255 QQHLLSLQR----QGLISIPPGQAALPVQ-SLPQ 283
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 53.9 bits (128), Expect = 7e-07
Identities = 78/317 (24%), Positives = 116/317 (36%), Gaps = 52/317 (16%)
Query: 408 REQMLQNPQQAT-PAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYK--QDFTNSK- 463
R M + P + T P P M+ PS V Y ++PA P + Q S+
Sbjct: 1862 RLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSV-YRQQQPAVPQGQRLRQQLQQSQG 1920
Query: 464 LLMMPSVNKSSPRPG---------GPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGN 514
+L SV++ +P PY+ SHV L H P+ G
Sbjct: 1921 MLGQSSVHQMTPSSSYGLQTSQGYTPYV--SHVGLQQHTGPA----------------GT 1962
Query: 515 TKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVP 574
P S+ P + + +L Q+ S H+Q + G +
Sbjct: 1963 MVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTY----GHGLTSTQRFSH 2018
Query: 575 PGQEQNP---SSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQL----- 626
+Q P + P+ AQ G + A+ QQQ +Q Q
Sbjct: 2019 QTLQQTPMISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYH 2078
Query: 627 --------LLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQ 678
+L QQ+Q++QQQ+ QQQQ Q+QQ Q++QQ Q +P PQ Q Q
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138
Query: 679 GSFPQQVGQFTGSSAAV 695
QQ Q ++A V
Sbjct: 2139 RQGLQQTQQQQQTAALV 2155
Score = 42.7 bits (99), Expect = 0.002
Identities = 86/366 (23%), Positives = 124/366 (33%), Gaps = 54/366 (14%)
Query: 351 SGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPG-----GASELSSAHQLQQIAAK 405
+G PR D P +P + R VLP+ G +S +S ++ QQ A
Sbjct: 1850 AGGPRVDPYRPVRLPMQ---KLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVP 1906
Query: 406 Q--KREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSK 463
Q + Q LQ Q GQ S Q T S L S +Q +
Sbjct: 1907 QGQRLRQQLQQSQGML-----GQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAG 1961
Query: 464 LLMMPSVNKSSPRPGGPYLQPSHVNLLSH--QPPSNLNQNSANNQGSVLDYGNTKPLSHY 521
++ PS + + P P+ V+ H Q PS A G L +T+ SH
Sbjct: 1962 TMVPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLT--STQRFSHQ 2019
Query: 522 KADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNP 581
Q P + P + S +++P Q+Q
Sbjct: 2020 TL----------QQTPMISTMTPMSAQGVQAGVRST-------------AILPEQQQQQQ 2056
Query: 582 SSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHL 641
Q Q Q + QQQ +Q Q QQ+Q++QQQ
Sbjct: 2057 QQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ--QQQQQQQQQQ--- 2111
Query: 642 QQQQFLQRQQHLLA-----EQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVP 696
QQQQ Q+QQ A Q + QFQR + Q Q + +Q+ Q ++ P
Sbjct: 2112 QQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQQ--TAALVRQLQQQLSNTQPQP 2169
Query: 697 GMNTLG 702
N G
Sbjct: 2170 STNIFG 2175
Score = 32.3 bits (72), Expect = 2.3
Identities = 83/376 (22%), Positives = 132/376 (35%), Gaps = 46/376 (12%)
Query: 76 QPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATSPQNGDQQNGYGDLFP 135
+PPA T P AP D P P+T + K++ Q + YG + P
Sbjct: 1750 EPPAPTLLEPEKKAPEPPKTDKPGAAPPST--EERKKKSTKGKKRSQPATKTEDYG-MGP 1806
Query: 136 GHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSS 195
G R P GV + + L +P G+ + + S+GL + N+ A
Sbjct: 1807 G-----RSGPYGVTVPPDLLHHPNP--------GSITHLNYRQGSIGLYTQNQPLPA--- 1850
Query: 196 LHLNGGSNPSESFPLSL-NKELKQEPVED--LPCMITGTVGSISQSNLMPDLNLNEQEWK 252
GG P+ L ++L P LP +TG +G + S+ + +Q
Sbjct: 1851 ----GGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMG-LEPSSYKTSVYRQQQPAV 1905
Query: 253 ELIEELNRSVPDEDMKDLFNEDFEEKKDPESS----GSATQTPLAQDINIKTEFSPAAFE 308
+ L + + + + + + + P SS S TP + ++ PA
Sbjct: 1906 PQGQRLRQQL--QQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTM 1963
Query: 309 QEQLGSPQVRAG---SAGQTFLGPS-------SAPVSTDSPSLG-GSQTLFHTSGQPRAD 357
S Q S T + P+ S V +P+ G G + S Q
Sbjct: 1964 VPPSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQ 2023
Query: 358 NPSPNLM-PASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQ 416
P + M P SAQ A + +LP Q + Q QQ +Q+++Q Q
Sbjct: 2024 TPMISTMTPMSAQGVQA-GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQ 2082
Query: 417 QATPAPAPGQMSTWQQ 432
Q Q QQ
Sbjct: 2083 QQQQILRQQQQQQQQQ 2098
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 53.9 bits (128), Expect = 7e-07
Identities = 94/416 (22%), Positives = 138/416 (33%), Gaps = 60/416 (14%)
Query: 309 QEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASA 368
Q G P A G GP SLGG +L GQP + + P P ++
Sbjct: 86 QSLTGGPAAGAAGIGMPPRGPGQ--------SLGGMGSL-GAMGQPMSLSGQPP--PGTS 134
Query: 369 QAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMS 428
A+ P + QLQQ+A +Q+++Q QQ Q
Sbjct: 135 GMAPHSMAVVSTATPQ----------TQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQ 184
Query: 429 TWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQPSHVN 488
QQ S++ + +Q L+ + N+ + LQ +
Sbjct: 185 QQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQ--RIA 242
Query: 489 LLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLS 548
L Q Q Q L +A P Q +P LPQQL
Sbjct: 243 QLQLQQQQQQQQQQQQQQQQAL-----------QAQPPIQQPPMQQPQPPPSQALPQQLQ 291
Query: 549 HISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNS 608
+ H Q+ +P P + PP + PS +P Q+Q + +Q A+ +
Sbjct: 292 QMHHTQHH----QPPP-----QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342
Query: 609 SPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQ-----------RQQHLLAEQ 657
P L + V++Q + Q Q +QQQ +Q Q Q L +
Sbjct: 343 PP-LKFVRAPMVVQQPPV----QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPS 397
Query: 658 EKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFP 713
QQ Q + PPP P G P SS P ++ PS S P P
Sbjct: 398 PGQQVQTPQSMPPPPQPSPQPGQ-PSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSP 452
Score = 51.2 bits (121), Expect = 5e-06
Identities = 112/448 (25%), Positives = 151/448 (33%), Gaps = 77/448 (17%)
Query: 478 GGPYLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKP 537
GGP + + + PP Q S GS+ G LS GQ PG+ P
Sbjct: 90 GGPAAGAAGIGM----PPRGPGQ-SLGGMGSLGAMGQPMSLS------GQPPPGTSGMAP 138
Query: 538 ALMAYLP-------------------QQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQE 578
MA + QQ +Q +L + + F++ Q+
Sbjct: 139 HSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQ 198
Query: 579 QNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQ 638
Q + V Q Q Q + N QQQ + Q QL QQ+Q++QQQ
Sbjct: 199 QFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQ 258
Query: 639 KHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGM 698
QQQQ LQ Q + QQ P Q Q P + PQQ+ Q + P
Sbjct: 259 ---QQQQALQAQPPI------QQ------PPMQQPQPPPSQALPQQLQQMHHTQHHQP-- 301
Query: 699 NTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYG 758
P P Q L P VS PG Q L
Sbjct: 302 ---PPQPQQPPVAQNQPSQLPPQSQTQPLVSQ-----------AQALPGQMLYTQPPLKF 347
Query: 759 MASGITQIVAQPPPQATNGHAHIPRQT-NVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLN 817
+ + +V QPP Q QT Q + Q+SL LS +
Sbjct: 348 VRA--PMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPM--LSSPSPGQQVQ 403
Query: 818 PGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMS 877
+ PP P+ SP GQ SS + + SG P S+ P S Q+ +
Sbjct: 404 TPQSMPPPPQPSP-QPGQPSSQPNSNVS--SGPAPSPSSFLP----SPSPQPSQSPVTAR 456
Query: 878 SPQ-FSQAVP---NRPMAPMSSAAAVGS 901
+PQ FS P N P+ P S + GS
Sbjct: 457 TPQNFSVPSPGPLNTPVNPSSVMSPAGS 484
Score = 51.2 bits (121), Expect = 5e-06
Identities = 92/411 (22%), Positives = 133/411 (32%), Gaps = 86/411 (20%)
Query: 560 MKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAVSVASSHNSSPYLS------ 613
M P+ + G P S+ Q + G P +++V S+ L
Sbjct: 101 MPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVAL 160
Query: 614 --SQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ-----QFQRHL 666
QQQ +Q Q L QQ+Q++QQQ+ QQ +Q+Q + +Q++Q Q Q+HL
Sbjct: 161 QQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL 220
Query: 667 TRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHA 726
+ Q Q QQ+ Q + + + Q L P
Sbjct: 221 IKLHHQNQ--------QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Query: 727 SVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQP--PPQATNGHAHIPRQ 784
P Q P SQ +PQ + Q QP PP A N + +P Q
Sbjct: 273 PPMQQP-----------QPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321
Query: 785 TNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGM 844
+ S + A L T+PP+ V M Q Q Q
Sbjct: 322 SQTQPLVSQAQALPGQML-----------------YTQPPLKFVRAPMVVQQPPVQPQ-- 362
Query: 845 PNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLP 904
QQ + + Q +Q V SS + S P
Sbjct: 363 ------------------------VQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSS--P 396
Query: 905 PVSAQQRTSAPAPAPPPTAPQQGLPGLSP-------AGPELGAFSQSPASQ 948
Q +T P PP +PQ G P P P +F SP+ Q
Sbjct: 397 SPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ 447
Score = 35.0 bits (79), Expect = 0.36
Identities = 64/273 (23%), Positives = 90/273 (32%), Gaps = 42/273 (15%)
Query: 392 ELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSL----------- 440
+L QLQ +Q+++Q Q QQA A P Q QQ P S
Sbjct: 237 QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHT 296
Query: 441 ----DVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP-YLQPS----HVNLLS 491
P P + P + + Q S+ P V+++ PG Y QP ++
Sbjct: 297 QHHQPPPQPQQPPVAQNQPSQLPPQSQ--TQPLVSQAQALPGQMLYTQPPLKFVRAPMVV 354
Query: 492 HQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQG--------SPGSGQSKPALMAYL 543
QPP Q Q + + + Q SPG P M
Sbjct: 355 QQPPV---QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPP 411
Query: 544 PQ---QLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV 600
PQ Q S + NS P P F P PS PV A+ + P
Sbjct: 412 PQPSPQPGQPSSQPNSNVSSGPAPSPSSFL----PSPSPQPSQSPVTARTPQNFSVPSPG 467
Query: 601 SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQ 633
+ + N S +S + + Q LD+ KQ
Sbjct: 468 PLNTPVNPSSVMS--PAGSSQAEEQQYLDKLKQ 498
Score = 30.4 bits (67), Expect = 8.8
Identities = 42/141 (29%), Positives = 55/141 (39%), Gaps = 12/141 (8%)
Query: 361 PNLMPASAQAQNA-QRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAT 419
P + P Q Q A Q A A ++ PG SS L + Q+ + P
Sbjct: 357 PPVQPQVQQQQTAVQTAQAAQMV---APGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQ 413
Query: 420 PAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGG 479
P+P PGQ S+ Q + SS P P SPS + S + N S P P G
Sbjct: 414 PSPQPGQPSS--QPNSNVSSGPAPSPSSFLPSPSPQP---SQSPVTARTPQNFSVPSP-G 467
Query: 480 PYLQPSHVNLLSHQPPSNLNQ 500
P P VN S P+ +Q
Sbjct: 468 PLNTP--VNPSSVMSPAGSSQ 486
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,638,556
Number of Sequences: 37866
Number of extensions: 2975995
Number of successful extensions: 26719
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 223
Number of HSP's successfully gapped in prelim test: 998
Number of HSP's that attempted gapping in prelim test: 16142
Number of HSP's gapped (non-prelim): 7520
length of query: 1016
length of database: 18,247,518
effective HSP length: 112
effective length of query: 904
effective length of database: 14,006,526
effective search space: 12661899504
effective search space used: 12661899504
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.