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Search of human proteins with 7661950
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
(1173 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 2350 0.0
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 90 1e-17
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 86 2e-16
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 85 4e-16
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 76 2e-13
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 76 2e-13
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 74 6e-13
gi|50962882 G patch domain containing 8 [Homo sapiens] 74 6e-13
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 73 1e-12
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 72 2e-12
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 72 3e-12
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 70 9e-12
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 70 9e-12
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 69 2e-11
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 69 3e-11
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 69 3e-11
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 69 3e-11
gi|33356174 pinin, desmosome associated protein [Homo sapiens] 69 3e-11
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 69 3e-11
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 69 3e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 68 4e-11
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 67 8e-11
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 66 2e-10
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 66 2e-10
gi|217330641 IWS1 homolog [Homo sapiens] 66 2e-10
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 66 2e-10
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 65 3e-10
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 65 3e-10
gi|24415404 MDN1, midasin homolog [Homo sapiens] 65 3e-10
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 65 4e-10
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 2350 bits (6089), Expect = 0.0
Identities = 1173/1173 (100%), Positives = 1173/1173 (100%)
Query: 1 MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEF 60
MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEF
Sbjct: 1 MSRGSIEIPLRDTDEVIELDFDQLPEGDEVISILKQEHTQLHIWIALALEYYKQGKTEEF 60
Query: 61 VKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMA 120
VKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMA
Sbjct: 61 VKLLEAARIDGNLDYRDHEKDQMTCLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMA 120
Query: 121 DKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYR 180
DKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYR
Sbjct: 121 DKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYR 180
Query: 181 GALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAV 240
GALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAV
Sbjct: 181 GALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAV 240
Query: 241 LELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTE 300
LELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTE
Sbjct: 241 LELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTE 300
Query: 301 VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENA 360
VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENA
Sbjct: 301 VEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENA 360
Query: 361 SQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQ 420
SQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQ
Sbjct: 361 SQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQ 420
Query: 421 ILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR 480
ILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR
Sbjct: 421 ILEQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDR 480
Query: 481 AKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAM 540
AKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAM
Sbjct: 481 AKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAM 540
Query: 541 ARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSD 600
ARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSD
Sbjct: 541 ARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSD 600
Query: 601 TYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHK 660
TYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHK
Sbjct: 601 TYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHK 660
Query: 661 GYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVV 720
GYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVV
Sbjct: 661 GYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVV 720
Query: 721 LYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVL 780
LYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVL
Sbjct: 721 LYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVL 780
Query: 781 NAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERE 840
NAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERE
Sbjct: 781 NAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERE 840
Query: 841 LRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKE 900
LRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKE
Sbjct: 841 LRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKE 900
Query: 901 KKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKR 960
KKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKR
Sbjct: 901 KKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKR 960
Query: 961 RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS 1020
RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS
Sbjct: 961 RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS 1020
Query: 1021 SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR 1080
SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR
Sbjct: 1021 SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR 1080
Query: 1081 SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDN 1140
SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDN
Sbjct: 1081 SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDN 1140
Query: 1141 EGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
EGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD
Sbjct: 1141 EGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 89.7 bits (221), Expect = 1e-17
Identities = 76/348 (21%), Positives = 142/348 (40%), Gaps = 43/348 (12%)
Query: 831 ARKQDEEERELRAKQEQEKELLR----QKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTK 886
A +EERE K + E+ R +K L E+EE + R+ EEQ++ ++R Q +K +
Sbjct: 666 AEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQ--KEREQGHQKER 723
Query: 887 NILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQE 946
N +E + GG ++ GE +E D +++ + K+ +G G E E
Sbjct: 724 N-----------QEMEEGG-----EEEHGEGEEEEGDREEEEEKEGEGKE--EGEGEEVE 765
Query: 947 GE-DEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMK 1005
GE ++E GERKK++R G+E ++E + G ++ + E+K+
Sbjct: 766 GEREKEEGERKKEER----AGKEEKGEEEGDQGEGEEEETEGRGEEKEE----------G 811
Query: 1006 GKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNK 1065
G+++ + + +E++ EG + E E+ + E + +E + +
Sbjct: 812 GEVEGGEVEEGKGEREEEEE---EGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGE 868
Query: 1066 SGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPAS 1125
E G + + + + + G + + E G G + +
Sbjct: 869 EEGEEGE-GEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEE 927
Query: 1126 PSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
E + E G +G G+G E E EG E G E G + +
Sbjct: 928 GEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGE 975
Score = 84.7 bits (208), Expect = 5e-16
Identities = 72/336 (21%), Positives = 138/336 (41%), Gaps = 26/336 (7%)
Query: 833 KQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFT 892
+++EEE+E K+E E E + + KE+ E++ E+ +++ E+ E +
Sbjct: 745 REEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEE----- 799
Query: 893 GETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEG 952
ETE E+K GG +GGE +E + +++ + +G E EGE+EEG
Sbjct: 800 -ETEGRGEEKEEGG----EVEGGEVEEGKGEREEEE-------EEGEGEEEEGEGEEEEG 847
Query: 953 -GERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSK 1011
GE ++ + + +GEEG ++E E G + + E ++ + E +G+ + +
Sbjct: 848 EGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEE 907
Query: 1012 AIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAG 1071
+ +E + K +EG + +E+E + E + +E + + E
Sbjct: 908 G---EGEGEEEEGEGKGEEEGE----EGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE 960
Query: 1072 SPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESD 1131
+ + + + + + E + E + G E E +
Sbjct: 961 EGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGE 1020
Query: 1132 HESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEH 1167
E E + EG G+G E E EG E G E+
Sbjct: 1021 VEGEVEGE-EGEGEGEEEEGEEEGEEREKEGEGEEN 1055
Score = 55.8 bits (133), Expect = 2e-07
Identities = 61/285 (21%), Positives = 118/285 (41%), Gaps = 43/285 (15%)
Query: 835 DEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGE 894
+EEE E ++E E E ++ E EE+ E EE++ GE
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE--------------------GE 918
Query: 895 TEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGE 954
+ +E + G G G + GE ++ + +++ +G E EGE EE GE
Sbjct: 919 GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE-------GEWEGEEEEGEGEGEEEGE 971
Query: 955 RKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAII 1014
+ ++ + EEG + E E G + + E+ + E ++G+++ +
Sbjct: 972 GEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGE 1031
Query: 1015 SSSDDSSDEDKLKIAD-EGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSE---- 1069
++ E++ + + EG + N + +E+E+ K E+ +EN+ + G E
Sbjct: 1032 GEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGK---YQETGEEENERQDGEEYKKV 1088
Query: 1070 ---AGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGR 1111
GS + + + + S ++ + +G EQ VQS R
Sbjct: 1089 SKIKGSVKYGKHKTYQKKSVTN-----TQGNGKEQRSKMPVQSKR 1128
Score = 45.4 bits (106), Expect = 3e-04
Identities = 54/304 (17%), Positives = 118/304 (38%), Gaps = 17/304 (5%)
Query: 836 EEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGET 895
EE + R ++E+E E ++ E+EE E+E + K E+ + + + GE
Sbjct: 820 EEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE---EGEG 876
Query: 896 EATKEKKRGGGG----GRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
E +E+ G G G ++ GE + + + + + K +G E EGE+EE
Sbjct: 877 EGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936
Query: 952 G--------GERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPS 1003
G GE ++++ + EEG + E E + ++ E++ + E
Sbjct: 937 GEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGE 996
Query: 1004 MKGKIKSKAIISSSDDSSDEDKLKIADE--GHPRNSNSNSDSDEDEQRKKCASSESDSDE 1061
+G+ + + + +E++ ++ E G + E+E ++ E + +
Sbjct: 997 EEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENR 1056
Query: 1062 NQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDS 1121
+ E + + ++ D ++ + + GS + +S + N
Sbjct: 1057 RNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKKSVTNTQGNGK 1116
Query: 1122 RPAS 1125
S
Sbjct: 1117 EQRS 1120
Score = 44.7 bits (104), Expect = 5e-04
Identities = 71/349 (20%), Positives = 133/349 (38%), Gaps = 59/349 (16%)
Query: 852 LRQKLLKEQEEKRLREKEEQKKLLEQRAQYVE-----------KTKNILMFTGETEA-TK 899
L++ +L EQ+ L + EE LL++ + E +T +IL T +
Sbjct: 455 LQESVLSEQD---LMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSLNSN 511
Query: 900 EKKRGGGGGRRSKKGGEFDEFV-------NDDTDDDLPISKKKKRRKGSGSEQEG----- 947
EK ++ KK E NDD+D+ +S+ K+ + +G
Sbjct: 512 EKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQ 571
Query: 948 --------EDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPER 999
DEE ++K+ KG G ++ E E + K + EK + +
Sbjct: 572 PATTIEAFSDEEVEIPEEKEGAEDSKGN-GIEEQEVEANEENVKVHGGRKEKTEILSDDL 630
Query: 1000 LPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDS 1059
+ + K+K++ + D +G +S ++ +DE+R+K +
Sbjct: 631 TDKAEVSEGKAKSVGEAEDGPEGRG------DGTCEEGSSGAEHWQDEEREKGEKDKGRG 684
Query: 1060 DENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSG-RSHSGVSE 1118
+ + G + + + ++R D ++ +K R G ++ N+ ++ G G E
Sbjct: 685 EMERPGEGEKELAEKEEWKKR-----DGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGE 739
Query: 1119 NDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGS-NNEASDRGSE 1166
+ E D E E + EG G+ G E EG E +R E
Sbjct: 740 EE--------EGDREEEE--EKEGEGKEEGEGEEVEGEREKEEGERKKE 778
Score = 32.0 bits (71), Expect = 3.6
Identities = 43/224 (19%), Positives = 83/224 (37%), Gaps = 10/224 (4%)
Query: 957 KKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISS 1016
+K++++ GE D TEN + + ++ KA K + + + + I +
Sbjct: 521 QKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACK-QHVSQGIFMTQPATTIEAF 579
Query: 1017 SDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESD-----SDENQNKSGSEAG 1071
SD+ + + K E N + + +E+ K + SD+ +K+ G
Sbjct: 580 SDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEG 639
Query: 1072 SPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAE-S 1130
+ + D + SG+E +E + G G E + RP E +
Sbjct: 640 KAKSVGEAEDGPEGRGDGTCEEGS-SGAEHWQDEEREKGEKDKGRGEME-RPGEGEKELA 697
Query: 1131 DHESERGSDNEGSGQGSGNESEPEGSNNEASDRG-SEHGSDDSD 1173
+ E + D E Q + + N E + G EHG + +
Sbjct: 698 EKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEE 741
Score = 30.8 bits (68), Expect = 7.9
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 7/86 (8%)
Query: 833 KQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQY--VEKTKNILM 890
++ EEE E R K+ + +E R + +E+EE + +E E++ + +Y V K K +
Sbjct: 1037 EEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVK 1096
Query: 891 FTGETEATKEKK----RGGGGGRRSK 912
+ G+ + ++K +G G +RSK
Sbjct: 1097 Y-GKHKTYQKKSVTNTQGNGKEQRSK 1121
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 85.9 bits (211), Expect = 2e-16
Identities = 77/378 (20%), Positives = 156/378 (41%), Gaps = 43/378 (11%)
Query: 830 RARKQDEEERELRAKQEQEKELLR-QKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNI 888
R R++ + ERE K+E+ +E R +K + +E +R REKE +++ +R + EK +N
Sbjct: 64 RRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERN- 122
Query: 889 LMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKR-RKGSGSEQEG 947
+ E +E +R G GR + G+ + D + + ++R R+ + Q+
Sbjct: 123 ----RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 948 EDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPP------------------KA 989
+ E +++++R R + E ++D +E G + ++ R K
Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238
Query: 990 EKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDED-KLKIADEGHPRNSNSNSDSDEDEQ 1048
E+++ + ER S + + K D D D + K + R ++ D + +
Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
Query: 1049 RKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
RK+ E + + +N+ R R ++ + + D ++ ++R +E + Q
Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQ 358
Query: 1109 SG----------------RSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESE 1152
+G R E + R + E ER ++ + GQ E +
Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRE-TEKQ 417
Query: 1153 PEGSNNEASDRGSEHGSD 1170
E + S+RG E G +
Sbjct: 418 REREKDRESERGRERGRE 435
Score = 57.4 bits (137), Expect = 8e-08
Identities = 72/363 (19%), Positives = 135/363 (37%), Gaps = 59/363 (16%)
Query: 848 EKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEK--KRGG 905
++E RQK + + EKR E+E +K E +EK R
Sbjct: 53 DRERNRQKERERRREKRQTERETDRK---------------------RERRREKDRHRKR 91
Query: 906 GGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEG------GERKKKK 959
R ++ E + D + D K++ R+K E E E E G G+R++++
Sbjct: 92 DRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERER 151
Query: 960 RRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPP-----------SMKGKI 1008
+R K E D E + + +++ + EK + + ER S +G+
Sbjct: 152 QRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRE 211
Query: 1009 KSKAIISSSD------DSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDEN 1062
+ + + ++ + D+ + + + + S+ + +R K E D D +
Sbjct: 212 RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRD 271
Query: 1063 QNKSGSE-AGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEND- 1120
+++ E R R++R+++D ++++ ++R E+ N + R E
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR 331
Query: 1121 ----------SRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSD 1170
R E D E R + EG Q E E E + S R E
Sbjct: 332 ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAE-RERERERERDRQSAREREERER 390
Query: 1171 DSD 1173
D D
Sbjct: 391 DRD 393
Score = 56.6 bits (135), Expect = 1e-07
Identities = 72/350 (20%), Positives = 136/350 (38%), Gaps = 41/350 (11%)
Query: 823 QAQYHVARARKQDEE-ERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQY 881
+ + R R+ D E +R+ + ++E+EK+ R++ E+E +R +E+E ++ R +
Sbjct: 217 ETETETERKRQTDRERDRQRKTEREREKQAERERA-SERETERDKERERERDRDRDRDRR 275
Query: 882 VEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGS 941
+ E E ++KR RR+++ E + + + + +KR +
Sbjct: 276 QK----------ERERQTDRKR----QRRTERDRETERKRERQRERERERERNRKRERER 321
Query: 942 GSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLP 1001
E+E E + ER ++K R + + D E + RR + E+++ + +R
Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDR-- 379
Query: 1002 PSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSD- 1060
+S + D D+ K + ++ + ++++ +R+K SE +
Sbjct: 380 -------QSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRER 432
Query: 1061 --ENQNKSGSEAGSPRRPRRQRSDQDSDSD---QPSRKRRPSGSEQSDNESVQSGRSHSG 1115
E + + G E R+ RQ Q S P + SG QSD G
Sbjct: 433 GREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKS 492
Query: 1116 VSEND---------SRPASPSAESDHESERGSDNEGSGQGSGNES-EPEG 1155
E+ RPA S R G +G G E P G
Sbjct: 493 SPEDPKAASTRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSG 542
Score = 55.1 bits (131), Expect = 4e-07
Identities = 63/281 (22%), Positives = 114/281 (40%), Gaps = 28/281 (9%)
Query: 830 RARKQDEEERELRAKQEQEKELLRQKLLKEQEE-KRLREKEEQKKLLEQRAQYVEKTKNI 888
+ +Q E ERE +++E+E R++ + Q E +R REKE ++K Q E+ +
Sbjct: 300 KRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQT 359
Query: 889 LMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGE 948
G +A +E++R R+S + E E D D D ++K+R + + +++G+
Sbjct: 360 GR-EGRRQAERERERERERDRQSAREREERE---RDRDRD----RQKERERQTEKDRDGQ 411
Query: 949 DEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKI 1008
E +R+++K R +G E + E + G + + R + + K L + +
Sbjct: 412 RETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRT 471
Query: 1009 KSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGS 1068
++ S D P S ED K AS+ S
Sbjct: 472 ARSGVVQS-------------DPNRPTRGIRWKSSPED---PKAASTRFPWGRPAKASRG 515
Query: 1069 EAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQS 1109
RR + ++ Q RRPSG ++N Q+
Sbjct: 516 RVAGRRRWEPRLGEK---RGQGGEGRRPSGGFGTENPLSQA 553
Score = 50.1 bits (118), Expect = 1e-05
Identities = 59/314 (18%), Positives = 125/314 (39%), Gaps = 29/314 (9%)
Query: 812 TEARQCSDLLSQAQYHVARARKQDEE-----ERELRAKQEQEKEL-------LRQKLLKE 859
TE ++ +D Q R R++ E ERE +E+E+E RQK +
Sbjct: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
Query: 860 QEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDE 919
Q +++ + + E+ + E++ E + +E++R R ++ E +
Sbjct: 282 QTDRKRQRRTERDRETERKR--------------ERQRERERERERNRKRERERERERER 327
Query: 920 FVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGP 979
+T+ D +++KR++ + ++E + G E +++ R + E E
Sbjct: 328 ERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREE 387
Query: 980 KPKKR-RPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSN 1038
+ + R R + E+++ + +R K + + S+ + + + +G R+
Sbjct: 388 RERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRE 447
Query: 1039 SNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRR-PS 1097
+D QRK+ ++ + +SG P RP R + S D + R P
Sbjct: 448 RQTDRQAGRQRKR-STLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPW 506
Query: 1098 GSEQSDNESVQSGR 1111
G + +GR
Sbjct: 507 GRPAKASRGRVAGR 520
Score = 46.6 bits (109), Expect = 1e-04
Identities = 47/284 (16%), Positives = 111/284 (39%), Gaps = 15/284 (5%)
Query: 889 LMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGE 948
L F+ ++E R G G+ K D N + +++RR+ +E+E +
Sbjct: 24 LDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKE-------RERRREKRQTERETD 76
Query: 949 DEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKI 1008
+ R+K + R+ + E D E E + + R + EK++ + ER + +
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGE 136
Query: 1009 KSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDEN-----Q 1063
+ + +D + ++ + A++ R ++ + R+K E + E Q
Sbjct: 137 RGRD--RQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ 194
Query: 1064 NKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDS-R 1122
+ ++ R + +++ +++ + ++R + E+ + R E S R
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254
Query: 1123 PASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSE 1166
E + E +R D + + +++ + DR +E
Sbjct: 255 ETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 85.1 bits (209), Expect = 4e-16
Identities = 64/264 (24%), Positives = 103/264 (39%), Gaps = 14/264 (5%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRR--HPKGEEGSDDDETENGP 979
N + D + + + G+GS+ +G +++ + + G G+DD++ +
Sbjct: 484 NSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSG 543
Query: 980 KPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNS 1039
K K + + S S + SS DSSD D +D +SNS
Sbjct: 544 KGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNS--SSDSDSSDSDSSDSSDSDSSDSSNS 601
Query: 1040 NSDSDE----------DEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQ 1089
+ SD D K SS+S+SD + + S S++ + SDS
Sbjct: 602 SDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSN 661
Query: 1090 PSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGN 1149
S S S S + S S S+S S + S ++ S SD SD+ S S +
Sbjct: 662 SSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721
Query: 1150 ESEPEGSNNEASDRGSEHGSDDSD 1173
S S+N + S + SD SD
Sbjct: 722 NSSDSDSSNSSDSSDSSNSSDSSD 745
Score = 80.9 bits (198), Expect = 7e-15
Identities = 61/250 (24%), Positives = 92/250 (36%), Gaps = 9/250 (3%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+D +D SK + S S+ + D + + SD + N
Sbjct: 617 SDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS--------DSSDSSNSSNSSDS 668
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNS 1041
+ S + + S S DSSD D +D + +S+S+S
Sbjct: 669 SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDS 728
Query: 1042 DSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ 1101
+ D +S SDS ++ N S S S SD SDS S S S
Sbjct: 729 SNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS-SDSSDSSDSSNSSDSND 787
Query: 1102 SDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEAS 1161
S N S S S+S S N S + S SD +S SD+ S S + + + S++ S
Sbjct: 788 SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDS 847
Query: 1162 DRGSEHGSDD 1171
GS+ S +
Sbjct: 848 SDGSDSDSSN 857
Score = 78.6 bits (192), Expect = 3e-14
Identities = 60/274 (21%), Positives = 102/274 (37%), Gaps = 15/274 (5%)
Query: 900 EKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKK 959
+K G G S D + D+ D S S S+ + D + +
Sbjct: 538 DKSDSGKGKSDSSDSDSSDSSNSSDSSDS---SDSDSSDSNSSSDSDSSDSDSSDSSDSD 594
Query: 960 RRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDD 1019
+ SD ++ + K++ K+ S KS + S+S D
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD-----SSDSDSKSDSSDSNSSD 649
Query: 1020 SSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQ 1079
SSD +D NS+++SDS + +SS S+ + + S++ +
Sbjct: 650 SSDN-----SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704
Query: 1080 RSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSD 1139
DSDS S + S+ + S S S + +DS +S S++S S+ S
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD--SS 762
Query: 1140 NEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
N S + S+ S+N + S + SD SD
Sbjct: 763 NSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSD 796
Score = 77.0 bits (188), Expect = 1e-13
Identities = 68/289 (23%), Positives = 106/289 (36%), Gaps = 16/289 (5%)
Query: 893 GETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEG 952
G+ ++ + G G SK +D D D G+G+ ++++
Sbjct: 489 GDASYNSDESKDNGNGSDSKGA--------EDDDSDSTSDTNNSDSNGNGNNGNDDNDKS 540
Query: 953 GERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKA 1012
K K + S+ ++ + + + + S S
Sbjct: 541 DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSN 600
Query: 1013 IISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSES---DSDENQNKSGSE 1069
SSD S D +D ++ +S S+SD + K SS+S DS +N + S S
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 1070 AGSPRRPRRQRSD--QDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSE-NDSRPASP 1126
S SD S S S S S S N S S S S S+ +DS +S
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 1127 SAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSE--HGSDDSD 1173
S SD +S SD+ S S + + SN+ S S+ + SD SD
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD 769
Score = 73.9 bits (180), Expect = 8e-13
Identities = 53/265 (20%), Positives = 93/265 (35%), Gaps = 2/265 (0%)
Query: 911 SKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGS 970
S D + D+ + S S S + + + S
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 971 DDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIAD 1030
D + ++ + S + S S DSSD +D
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 1031 EGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQP 1090
+ +S+++SDS + + S SD N++ + S++ S S+S
Sbjct: 855 SSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDS 914
Query: 1091 SRKRRPSGSEQSDNESVQSGRSHSGVS--ENDSRPASPSAESDHESERGSDNEGSGQGSG 1148
S S S +S N S S S S S +DS +S S++S + S+ + ++ S S
Sbjct: 915 SDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSS 974
Query: 1149 NESEPEGSNNEASDRGSEHGSDDSD 1173
+ S+ S++ + S SD SD
Sbjct: 975 DSSDSSNSSDSSDSSDSSDSSDSSD 999
Score = 72.4 bits (176), Expect = 2e-12
Identities = 51/252 (20%), Positives = 88/252 (34%), Gaps = 1/252 (0%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+D +D D S S S+ + SD ++ +
Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNS 1041
+ + + S+S DSS+ + + +S+++S
Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824
Query: 1042 DSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ 1101
DS ++S SD + + GS++ S R S SDS S S S
Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSD 884
Query: 1102 SDNESVQSGRS-HSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEA 1160
S+ S S S S S++DS +S S++S S +E S + S +++++
Sbjct: 885 SNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDS 944
Query: 1161 SDRGSEHGSDDS 1172
SD S DS
Sbjct: 945 SDSSDSSNSSDS 956
Score = 72.4 bits (176), Expect = 2e-12
Identities = 51/252 (20%), Positives = 86/252 (34%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+ ++ D S S S + +G + R + SD ++ N
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDS 879
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNS 1041
+ + S S SSD S+ D + ++ NS+ +S
Sbjct: 880 SDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSS 939
Query: 1042 DSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ 1101
+S + ++S S+ + + + S++ S SDS S S S
Sbjct: 940 NSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSD 999
Query: 1102 SDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEAS 1161
S N S S S S S N S ++ S S+ S + S + S+ S+N +
Sbjct: 1000 SSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1059
Query: 1162 DRGSEHGSDDSD 1173
S SD SD
Sbjct: 1060 SSDSSDSSDSSD 1071
Score = 72.0 bits (175), Expect = 3e-12
Identities = 58/270 (21%), Positives = 96/270 (35%), Gaps = 8/270 (2%)
Query: 910 RSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEG 969
RS D + D+ + S + S S + + +
Sbjct: 858 RSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS 917
Query: 970 SDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIA 1029
S+ ++ + + S + + S+S DSSD + +
Sbjct: 918 SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSS 977
Query: 1030 DEGHPRNSNSNSDSDE-----DEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQD 1084
D + +S+ +SDS + D +S SDS ++ N S S S SD
Sbjct: 978 DSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD-S 1036
Query: 1085 SDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVS--ENDSRPASPSAESDHESERGSDNEG 1142
SDS S S S S N S S S S S +DS +S S+ES S+ + ++
Sbjct: 1037 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDS 1096
Query: 1143 SGQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
S ++S ++++SD S DS
Sbjct: 1097 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Score = 71.6 bits (174), Expect = 4e-12
Identities = 56/252 (22%), Positives = 87/252 (34%), Gaps = 17/252 (6%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+D +D D S S S + + + K SD ++E+
Sbjct: 580 SDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK----SDSSKSESDSSD 635
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNS 1041
+ ++ + + S + + S S DSSD + NS+ +S
Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDS-----SSSSDSSNSSDSS 690
Query: 1042 DSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ 1101
DS + + + S SD + + S + S + DSDS S S S
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNS--------NSSDSDSSNSSDSSDSSNSSD 742
Query: 1102 SDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEAS 1161
S + S S S S S + S + S SD S N S N S+ S+N +
Sbjct: 743 SSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSD 802
Query: 1162 DRGSEHGSDDSD 1173
S SD SD
Sbjct: 803 SSNSSDSSDSSD 814
Score = 70.1 bits (170), Expect = 1e-11
Identities = 50/257 (19%), Positives = 91/257 (35%), Gaps = 6/257 (2%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+D +D D S + D + S D + +
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSS 690
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSD-----DSSDEDKLKIADEGHPRN 1036
+ + S S + S SD DSSD + + +
Sbjct: 691 DSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSS 750
Query: 1037 SNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRP 1096
++S+S D +S SDS ++ + S S + SD + SD +
Sbjct: 751 NSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSS 810
Query: 1097 SGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGS 1156
S+ SD++S S S + +DS +S S++S S+ GSD++ S + + S
Sbjct: 811 DSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD-GSDSDSSNRSDSSNSSDSSD 869
Query: 1157 NNEASDRGSEHGSDDSD 1173
++++S+ S DS+
Sbjct: 870 SSDSSNSSDSSDSSDSN 886
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/289 (19%), Positives = 91/289 (31%), Gaps = 12/289 (4%)
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
+ ++ + + S D + D+ D S S S + +
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 952 GGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSK 1011
+ E SD ++ N + + S
Sbjct: 1072 SSDSSDSS-----DSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1126
Query: 1012 AIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAG 1071
+ S S DSSD + + + +S+S D +S SDS ++ N S S
Sbjct: 1127 SDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186
Query: 1072 SPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDN-------ESVQSGRSHSGVSENDSRPA 1124
S SD SD S+ SD+ +S S S +DS +
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246
Query: 1125 SPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
S S++S S+ S S ++S+ NN SD S+ DS+
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSN 1295
Score = 68.9 bits (167), Expect = 3e-11
Identities = 55/286 (19%), Positives = 100/286 (34%), Gaps = 6/286 (2%)
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
+ ++ + + S D + D++D S S S + +
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 952 GGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPK--AEKKKAPKPERLPPSMKGKIK 1009
+ SD ++ N ++ + + + S
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871
Query: 1010 SKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSE 1069
+ S S DSSD + + ++ +S+++SDSD + SS+S + + ++S +
Sbjct: 872 DSSNSSDSSDSSDSN--ESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNS 929
Query: 1070 AGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDN--ESVQSGRSHSGVSENDSRPASPS 1127
+ + S SDS S S S S N +S S S S S N S + S
Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989
Query: 1128 AESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
SD S N S + S+ S++ ++ S + SD SD
Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 1035
Score = 68.9 bits (167), Expect = 3e-11
Identities = 53/256 (20%), Positives = 88/256 (34%), Gaps = 6/256 (2%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+D +D R S + + D E + D +++
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNS 1041
+ + S + S +SSD S+ D +D + +S+++S
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESS-NSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 1042 DSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ 1101
DS SS+S N + S + S S SDS S S S
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 1102 SDNESVQSGRSHSGVS-----ENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGS 1156
S N S S S S S +DS +S S++S + S+ ++ S ++S
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD 1080
Query: 1157 NNEASDRGSEHGSDDS 1172
++E+SD S DS
Sbjct: 1081 SSESSDSSDSSNSSDS 1096
Score = 68.2 bits (165), Expect = 4e-11
Identities = 55/262 (20%), Positives = 86/262 (32%), Gaps = 4/262 (1%)
Query: 911 SKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGS 970
S D + D+ D S S S + + + S
Sbjct: 998 SDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Query: 971 DDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIAD 1030
D + ++ + + S S + SSD S D +D
Sbjct: 1058 SDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSS-DSSDSSDSSDSSDSSD 1116
Query: 1031 EGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQP 1090
NS+ +SDS D +S+ SDS ++ S S S SD SD
Sbjct: 1117 SSDSSNSSDSSDS-SDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSS 1175
Query: 1091 SRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNE 1150
S+ SD S S S +DS +S S++S S+ ++ S NE
Sbjct: 1176 DSSNSSDSSDSSD--SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNE 1233
Query: 1151 SEPEGSNNEASDRGSEHGSDDS 1172
S ++++SD + S DS
Sbjct: 1234 SSDSSDSSDSSDSSNSSDSSDS 1255
Score = 67.8 bits (164), Expect = 6e-11
Identities = 53/252 (21%), Positives = 94/252 (37%), Gaps = 9/252 (3%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+ D+ D S S S + + + + SD ++ N
Sbjct: 665 SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNS 1041
++ + S S + SSD S+ D +D +S+S++
Sbjct: 725 DSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS-DSSDSSNSSDSSDSSDSSD--SSDSSN 781
Query: 1042 DSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ 1101
SD ++ +S+ SDS ++ N S S S SD DS + S S
Sbjct: 782 SSDSND-----SSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSS 836
Query: 1102 SDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEAS 1161
+ ++S S S G S++DS S S+ S S+ + S ++S +++++S
Sbjct: 837 NSSDSSDSSDSSDG-SDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895
Query: 1162 DRGSEHGSDDSD 1173
D + SD SD
Sbjct: 896 DSSNSSDSDSSD 907
Score = 66.6 bits (161), Expect = 1e-10
Identities = 57/258 (22%), Positives = 91/258 (35%), Gaps = 5/258 (1%)
Query: 918 DEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETEN 977
D + D+ D S + S + + + + S D +
Sbjct: 907 DSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSS 966
Query: 978 GPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDE-DKLKIADEGHPRN 1036
+ + S + S S DSSD D +D + +
Sbjct: 967 DSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSD 1026
Query: 1037 SNSNSDSDE--DEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKR 1094
S+++SDS + D +S SDS ++ N S S S SD SDS S
Sbjct: 1027 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD-SSDSSDSSESS 1085
Query: 1095 RPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPE 1154
S S S + S S S S S +DS +S S++S + S+ ++ S + S
Sbjct: 1086 DSSDSSNSSDSSDSSDSSDSSDS-SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 1144
Query: 1155 GSNNEASDRGSEHGSDDS 1172
++E+SD S DS
Sbjct: 1145 SDSSESSDSSDSSDSSDS 1162
Score = 65.5 bits (158), Expect = 3e-10
Identities = 40/148 (27%), Positives = 62/148 (41%), Gaps = 1/148 (0%)
Query: 1015 SSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPR 1074
S S DSSD + + + +SNS D +S SDS ++ + S S S
Sbjct: 1154 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1213
Query: 1075 RPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHES 1134
SD SD S+ SD+ + S S++ + + ESD +S
Sbjct: 1214 SDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS 1273
Query: 1135 ERGSDNEGSGQGSGNESEPEGSNNEASD 1162
+ G+ N +G S ++SE SN+ SD
Sbjct: 1274 KSGNGN-NNGSDSDSDSEGSDSNHSTSD 1300
Score = 64.3 bits (155), Expect = 6e-10
Identities = 75/328 (22%), Positives = 124/328 (37%), Gaps = 39/328 (11%)
Query: 861 EEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKK------RGGGGGRRS--K 912
E+ + E+ +KL + ++ VE N + ET A + + +G G R+ K
Sbjct: 334 EDNGSQRIEDTQKLNHRESKRVE---NRITKESETHAVGKSQDKGIEIKGPSSGNRNITK 390
Query: 913 KGGEFDEFVNDDTDDDLPISKKKKRRKGS--GSEQEGEDEEGGERKKKKRRRHPKGEEGS 970
+ G+ +E D + + K + +G E G+ E G + +G
Sbjct: 391 EVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGY 450
Query: 971 D----DDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKL 1026
D DD++ G P + + S + +SDE K
Sbjct: 451 DSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSR----------GDASYNSDESK- 499
Query: 1027 KIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSD 1086
D G+ +S D D D S ++SD N N + + + + SD
Sbjct: 500 ---DNGNGSDSKGAEDDDSDS-----TSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSD 551
Query: 1087 SDQPSRKRRPSGSEQSDNESVQSGRSH-SGVSENDSRPASPSAESDHESERGSDNEGSGQ 1145
SD S+ SD++S S S S S++DS +S S SD S SD+ S
Sbjct: 552 SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSD--SSNSSDSSDSSD 609
Query: 1146 GSGNESEPEGSNNEASDRGSEHGSDDSD 1173
S + + S++++ SE S DSD
Sbjct: 610 SSDSSDSSDSSDSKSDSSKSESDSSDSD 637
Score = 63.9 bits (154), Expect = 8e-10
Identities = 65/287 (22%), Positives = 103/287 (35%), Gaps = 11/287 (3%)
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
+ ++ + + S D + D+ D S S S + +
Sbjct: 1018 SSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSD 1077
Query: 952 GGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSK 1011
+ + S D + ++ + S S
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137
Query: 1012 AIISS--SDDSSDEDKLKIADEGHPRNSNSNSDSDE--DEQRKKCASSESDSDENQNKSG 1067
+ SS SD S D +D +S+ +SDS + D +S SDS ++ + S
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197
Query: 1068 SEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEN--DSRPAS 1125
S S SD SDS S S S S+ S S S S S N DS +S
Sbjct: 1198 SSDSSDSSDSSDSSD-SSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSS 1256
Query: 1126 PSAESDHESERGSDNEG-SGQGSGNESEPEGSNNEASDRGSEHGSDD 1171
S++S +S SD++ SG G+ N S+ + S++E SD S H + D
Sbjct: 1257 DSSDSTSDSNDESDSQSKSGNGNNNGSDSD-SDSEGSD--SNHSTSD 1300
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/260 (19%), Positives = 92/260 (35%), Gaps = 10/260 (3%)
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKP 981
+ D+ D S S S + E + SD + +
Sbjct: 668 SSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSD 727
Query: 982 KKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISS--SDDSSDEDKLKIADEGHPRNSNS 1039
++ + S S + SS SD S D +D + +S+S
Sbjct: 728 SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSN--SSDS 785
Query: 1040 NSDSD----EDEQRKKCASSESDSDENQNKSGSEA--GSPRRPRRQRSDQDSDSDQPSRK 1093
N S+ D +S+ SDS ++ + S S++ S SD + SD
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 1094 RRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEP 1153
GS+ + S S +DS +S S++S +E + ++ S + ++S+
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 1154 EGSNNEASDRGSEHGSDDSD 1173
S+N + S + SD S+
Sbjct: 906 SDSSNSSDSSDSSNSSDSSE 925
Score = 45.8 bits (107), Expect = 2e-04
Identities = 54/278 (19%), Positives = 96/278 (34%), Gaps = 25/278 (8%)
Query: 897 ATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERK 956
AT G + ++ G D N+D + + + GS + + EDE +
Sbjct: 148 ATNRSNTNGNTDKNTQNGDVGDAGHNEDV---AVVQEDGPQVAGSNNSTDNEDEI---IE 201
Query: 957 KKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISS 1016
R E + NG K + P E + P +
Sbjct: 202 NSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSG-----------NG 250
Query: 1017 SDDSSDEDKLKIADE--GHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPR 1074
+D+ DE DE G+ ++S++NS E + K + DS QN E P
Sbjct: 251 ADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGK--EDDHDSSIGQNSDSKEYYDPE 308
Query: 1075 RPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRS----HSGVSENDSRPASPSAES 1130
++ D D S + E + ++ ++ + S EN S +
Sbjct: 309 GKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAV 368
Query: 1131 DHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHG 1168
++G + +G G+ N ++ G NE + +HG
Sbjct: 369 GKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHG 406
Score = 44.3 bits (103), Expect = 7e-04
Identities = 57/326 (17%), Positives = 105/326 (32%), Gaps = 55/326 (16%)
Query: 893 GETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEG 952
G EA G G + G ++D D+ + ++ G S + +EG
Sbjct: 223 GTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEG 282
Query: 953 GERKKKKRRRHPKGE----------EGSDDDETE-NGPKPKKRRPPKAEKKKAPKPERLP 1001
+ K+ G+ EG +D E +G K K A + +R+
Sbjct: 283 QDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKSEENSAGIPEDNGSQRIE 342
Query: 1002 PSMK----------------------GKIKSKAIISSSDDSSDEDKLKIADEGHP----- 1034
+ K GK + K I S + + K +G+
Sbjct: 343 DTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDK 402
Query: 1035 -------RNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDS 1087
N + + SE + + +GS++ S D+
Sbjct: 403 GQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQG 462
Query: 1088 DQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGS 1147
D P+ +G++ +++ES N S S SD + G+ ++ G
Sbjct: 463 DDPNSSDESNGNDDANSES----------DNNSSSRGDASYNSDESKDNGNGSDSKGAED 512
Query: 1148 GNESEPEGSNNEASDRGSEHGSDDSD 1173
+ +NN S+ +G+DD+D
Sbjct: 513 DDSDSTSDTNNSDSNGNGNNGNDDND 538
Score = 41.6 bits (96), Expect = 0.004
Identities = 34/155 (21%), Positives = 61/155 (39%), Gaps = 13/155 (8%)
Query: 1028 IADEGHPRNSNSNSDSDEDEQRKKCASSESDSDEN--QNKSGSEAGSPRRPRRQ------ 1079
I + G SN+N ++D++ Q + + D Q AGS +
Sbjct: 143 IDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIEN 202
Query: 1080 --RSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERG 1137
R++ ++ P + +G++++ E +G+ +D P+ A+ D E E
Sbjct: 203 SCRNEGNTSEITPQINSKRNGTKEA--EVTPGTGEDAGLDNSDGSPSGNGADED-EDEGS 259
Query: 1138 SDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
D+E G+G +S E D G E D S
Sbjct: 260 GDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSS 294
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 75.9 bits (185), Expect = 2e-13
Identities = 93/458 (20%), Positives = 183/458 (39%), Gaps = 40/458 (8%)
Query: 158 QSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKA 217
Q P+N LL + I F + + + A++ NP AE +G+ + + +L++A
Sbjct: 40 QEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNP-LLAEAYSNLGNVYKERGQLQEA 98
Query: 218 RLAFSRALELNSKCVGALVGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLAN 277
+ AL L + + LA + A ++ VQ A +P V + L N
Sbjct: 99 IEHYRHALRLKPDFIDGYINLAAALV---AAGDMEGAVQAYVSALQYNPDLYCVRSDLGN 155
Query: 278 HFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFAS 337
K +++ E + A + L F+ Q + A ++ +A
Sbjct: 156 ---LLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL-D 211
Query: 338 SSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIA 397
+F+ + LG + + A + + L PN+ + G+L +Q D+A
Sbjct: 212 PNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNH---AVVHGNLACVYYEQGLIDLA 268
Query: 398 KGHLKKVTEQYPDDVEAWIELAQIL-EQTDIQGALSAYGTATRILQEKVQADVPPEILNN 456
++ E P +A+ LA L E+ + A Y TA R+ + LNN
Sbjct: 269 IDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADS------LNN 322
Query: 457 VGALHFRLGNLGEAKKYFLASLDR-AKAEAEHDE----------------HYYNAISVTT 499
+ + GN+ EA + + +L+ + A H HY AI ++
Sbjct: 323 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 382
Query: 500 SY-----NLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWF 554
++ N+ + M + A + Y ++ +P + D + L ++ +D GN EA +
Sbjct: 383 TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASY 442
Query: 555 KEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERIL 592
+ AL++ D PDA+ + + +W ++ ++++
Sbjct: 443 RTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLV 480
Score = 72.8 bits (177), Expect = 2e-12
Identities = 80/362 (22%), Positives = 151/362 (41%), Gaps = 33/362 (9%)
Query: 268 NPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQ 327
NP++ +N K+ ++Q H H ++ + LA + D + A Q
Sbjct: 75 NPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQ 134
Query: 328 YYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAA 387
Y A Q+ + + LG + G E A C+ K ++ PN LG ++ A
Sbjct: 135 AYVSALQYNPDLYCVRS-DLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNA 193
Query: 388 SEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDI-QGALSAYGTATRILQEKVQ 446
Q + +A H +K P+ ++A+I L +L++ I A++AY A +
Sbjct: 194 ---QGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAV 250
Query: 447 ADVPPEILNNVGALHFRLGNLG----------EAKKYF------LASLDRAKAE-AEHDE 489
+ N+ +++ G + E + +F LA+ + K AE ++
Sbjct: 251 ------VHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAED 304
Query: 490 HYYNAISVTTSY-----NLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDK 544
Y A+ + ++ NLA + EA +LY+ L P + + L ++ + +
Sbjct: 305 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQ 364
Query: 545 GNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYSM 604
G EA +KEA++I+ DA+S +GN Q+ + + R ++ +D +S
Sbjct: 365 GKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSN 424
Query: 605 LA 606
LA
Sbjct: 425 LA 426
Score = 62.8 bits (151), Expect = 2e-09
Identities = 88/416 (21%), Positives = 161/416 (38%), Gaps = 48/416 (11%)
Query: 355 GDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVT-EQYPDDVE 413
GD E A + ++ + P+N + +L S++ Q +R H + +Q P E
Sbjct: 25 GDFEAAERHCMQLWRQEPDNTGVLLLLSSIHF----QCRRLDRSAHFSTLAIKQNPLLAE 80
Query: 414 AWIELAQIL-EQTDIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKK 472
A+ L + E+ +Q A+ Y A R+ + + + N+ A G++ A +
Sbjct: 81 AYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYI------NLAAALVAAGDMEGAVQ 134
Query: 473 YFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVD 532
++++L YN +L L +A+ EA+ Y + PN+
Sbjct: 135 AYVSALQ------------YNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAV 182
Query: 533 CYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERIL 592
+ LG + +G + A F++A+ ++ + DA+ +GN+ + + + R L
Sbjct: 183 AWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRAL 242
Query: 593 KQPSTQSDTYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANG 652
+ + LA E+ D A+ Y++ + A
Sbjct: 243 SLSPNHAVVHGNLACVYY--------------EQGLIDLAIDTYRRAIELQPHFPDAYCN 288
Query: 653 IGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFY 712
+ L KG EA D + +D NLA+I EQ AV++Y L F
Sbjct: 289 LANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFP 348
Query: 713 K----HQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDTVLMFNVALVLQRL 764
+ H N LA L + GKLQE +A ++P+ N+ L+ +
Sbjct: 349 EFAAAHSN------LASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEM 398
Score = 60.8 bits (146), Expect = 7e-09
Identities = 107/513 (20%), Positives = 196/513 (38%), Gaps = 43/513 (8%)
Query: 128 QNHLLGRACFCL----LEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGAL 183
QN LL A L E ++ +A + L P+ I + A D GA+
Sbjct: 74 QNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAV 133
Query: 184 AYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLEL 243
Y AL+ NP VR +G+ L +LE+A+ + +A+E A L +
Sbjct: 134 QAYVSALQYNPDLYC-VRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFN 192
Query: 244 NNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEA 303
E I + +A T+DP+ +L N + + + L A + A
Sbjct: 193 AQGE---IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHA 249
Query: 304 MQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQC 363
+ + LA ++ Q D A Y +A + F + L +G A C
Sbjct: 250 VVHGN---LACVYYEQGLIDLAIDTYRRAIEL-QPHFPDAYCNLANALKEKGSVAEAEDC 305
Query: 364 FEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILE 423
+ L+ P + +++ L ++ +Q + A +K E +P+ A LA +L+
Sbjct: 306 YNTALRLCPTHADSLNNLANI---KREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ 362
Query: 424 QT-DIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAK 482
Q +Q AL Y A RI A +N+G + ++ A + + ++
Sbjct: 363 QQGKLQEALMHYKEAIRISPTFADA------YSNMGNTLKEMQDVQGALQCYTRAIQINP 416
Query: 483 AEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMAR 542
A A D H NLA +++ EA Y+ L+ P++ D Y L +
Sbjct: 417 AFA--DAH----------SNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 464
Query: 543 DKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTY 602
++ + + K+ + I D + + + ++H P F + + ++ +
Sbjct: 465 IVCDWTDYDERMKKLVSIVADQLEK-NRLPSVHPHHSMLYPLSHGFRKAI------AERH 517
Query: 603 SMLALGNVWLQTLHQPTRDREKEKRHQDRALAI 635
L L + LH+P + K+ + D L +
Sbjct: 518 GNLCLDKI--NVLHKPPYEHPKDLKLSDGRLRV 548
Score = 43.9 bits (102), Expect = 0.001
Identities = 54/258 (20%), Positives = 104/258 (40%), Gaps = 16/258 (6%)
Query: 121 DKIIMYDQNHL-----LGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFN 175
+K + D N L LG L E D+A A + L+ SPN+ AC+ +
Sbjct: 205 EKAVTLDPNFLDAYINLGNV---LKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 261
Query: 176 KKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGAL 235
+ A+ Y++A+ P P + + + + + +A ++ AL L +L
Sbjct: 262 QGLIDLAIDTYRRAIELQPHFP-DAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSL 320
Query: 236 VGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHA 295
LA ++ +E +I+ V+L +A + P ++LA+ + K+Q +H
Sbjct: 321 NNLANIK---REQGNIEEAVRLYRKALEVFPEFAAAHSNLAS---VLQQQGKLQEALMHY 374
Query: 296 FHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRG 355
+ A++ + + +D A Q Y +A Q + +F L ++ G
Sbjct: 375 KEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI-NPAFADAHSNLASIHKDSG 433
Query: 356 DKENASQCFEKVLKAYPN 373
+ A + LK P+
Sbjct: 434 NIPEAIASYRTALKLKPD 451
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 75.9 bits (185), Expect = 2e-13
Identities = 93/458 (20%), Positives = 183/458 (39%), Gaps = 40/458 (8%)
Query: 158 QSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKA 217
Q P+N LL + I F + + + A++ NP AE +G+ + + +L++A
Sbjct: 50 QEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQNP-LLAEAYSNLGNVYKERGQLQEA 108
Query: 218 RLAFSRALELNSKCVGALVGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLAN 277
+ AL L + + LA + A ++ VQ A +P V + L N
Sbjct: 109 IEHYRHALRLKPDFIDGYINLAAALV---AAGDMEGAVQAYVSALQYNPDLYCVRSDLGN 165
Query: 278 HFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFAS 337
K +++ E + A + L F+ Q + A ++ +A
Sbjct: 166 ---LLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTL-D 221
Query: 338 SSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIA 397
+F+ + LG + + A + + L PN+ + G+L +Q D+A
Sbjct: 222 PNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNH---AVVHGNLACVYYEQGLIDLA 278
Query: 398 KGHLKKVTEQYPDDVEAWIELAQIL-EQTDIQGALSAYGTATRILQEKVQADVPPEILNN 456
++ E P +A+ LA L E+ + A Y TA R+ + LNN
Sbjct: 279 IDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADS------LNN 332
Query: 457 VGALHFRLGNLGEAKKYFLASLDR-AKAEAEHDE----------------HYYNAISVTT 499
+ + GN+ EA + + +L+ + A H HY AI ++
Sbjct: 333 LANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISP 392
Query: 500 SY-----NLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWF 554
++ N+ + M + A + Y ++ +P + D + L ++ +D GN EA +
Sbjct: 393 TFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIASY 452
Query: 555 KEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERIL 592
+ AL++ D PDA+ + + +W ++ ++++
Sbjct: 453 RTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLV 490
Score = 72.8 bits (177), Expect = 2e-12
Identities = 80/362 (22%), Positives = 151/362 (41%), Gaps = 33/362 (9%)
Query: 268 NPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEAMQAESCYQLARSFHVQEDYDQAFQ 327
NP++ +N K+ ++Q H H ++ + LA + D + A Q
Sbjct: 85 NPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQ 144
Query: 328 YYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAA 387
Y A Q+ + + LG + G E A C+ K ++ PN LG ++ A
Sbjct: 145 AYVSALQYNPDLYCVRS-DLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNA 203
Query: 388 SEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILEQTDI-QGALSAYGTATRILQEKVQ 446
Q + +A H +K P+ ++A+I L +L++ I A++AY A +
Sbjct: 204 ---QGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAV 260
Query: 447 ADVPPEILNNVGALHFRLGNLG----------EAKKYF------LASLDRAKAE-AEHDE 489
+ N+ +++ G + E + +F LA+ + K AE ++
Sbjct: 261 ------VHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAED 314
Query: 490 HYYNAISVTTSY-----NLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDK 544
Y A+ + ++ NLA + EA +LY+ L P + + L ++ + +
Sbjct: 315 CYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQ 374
Query: 545 GNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYSM 604
G EA +KEA++I+ DA+S +GN Q+ + + R ++ +D +S
Sbjct: 375 GKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSN 434
Query: 605 LA 606
LA
Sbjct: 435 LA 436
Score = 63.5 bits (153), Expect = 1e-09
Identities = 92/433 (21%), Positives = 168/433 (38%), Gaps = 51/433 (11%)
Query: 341 VLPFFGLGQMY---IYRGDKENASQCFEKVLKAYPNNYETMKILGSLYAASEDQEKRDIA 397
+L F GL ++ GD E A + ++ + P+N + +L S++ Q +R
Sbjct: 18 MLSFQGLAELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHF----QCRRLDR 73
Query: 398 KGHLKKVT-EQYPDDVEAWIELAQIL-EQTDIQGALSAYGTATRILQEKVQADVPPEILN 455
H + +Q P EA+ L + E+ +Q A+ Y A R+ + + +
Sbjct: 74 SAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYI------ 127
Query: 456 NVGALHFRLGNLGEAKKYFLASLDRAKAEAEHDEHYYNAISVTTSYNLARLYEAMCEFHE 515
N+ A G++ A + ++++L YN +L L +A+ E
Sbjct: 128 NLAAALVAAGDMEGAVQAYVSALQ------------YNPDLYCVRSDLGNLLKALGRLEE 175
Query: 516 AEKLYKNILREHPNYVDCYLRLGAMARDKGNFYEASDWFKEALQINQDHPDAWSLIGNLH 575
A+ Y + PN+ + LG + +G + A F++A+ ++ + DA+ +GN+
Sbjct: 176 AKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVL 235
Query: 576 LAKQEWGPGQKKFERILKQPSTQSDTYSMLALGNVWLQTLHQPTRDREKEKRHQDRALAI 635
+ + + R L + + LA E+ D A+
Sbjct: 236 KEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYY--------------EQGLIDLAIDT 281
Query: 636 YKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADISDVWLNLAHIYVEQK 695
Y++ + A + L KG EA D + +D NLA+I EQ
Sbjct: 282 YRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQG 341
Query: 696 QYISAVQMYENCLRKFYK----HQNTEVVLYLARALFKCGKLQECKQTLLKARHVAPSDT 751
AV++Y L F + H N LA L + GKLQE +A ++P+
Sbjct: 342 NIEEAVRLYRKALEVFPEFAAAHSN------LASVLQQQGKLQEALMHYKEAIRISPTFA 395
Query: 752 VLMFNVALVLQRL 764
N+ L+ +
Sbjct: 396 DAYSNMGNTLKEM 408
Score = 60.8 bits (146), Expect = 7e-09
Identities = 107/513 (20%), Positives = 196/513 (38%), Gaps = 43/513 (8%)
Query: 128 QNHLLGRACFCL----LEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGAL 183
QN LL A L E ++ +A + L P+ I + A D GA+
Sbjct: 84 QNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAV 143
Query: 184 AYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLEL 243
Y AL+ NP VR +G+ L +LE+A+ + +A+E A L +
Sbjct: 144 QAYVSALQYNPDLYC-VRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFN 202
Query: 244 NNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHAFHNTEVEA 303
E I + +A T+DP+ +L N + + + L A + A
Sbjct: 203 AQGE---IWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHA 259
Query: 304 MQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRGDKENASQC 363
+ + LA ++ Q D A Y +A + F + L +G A C
Sbjct: 260 VVHGN---LACVYYEQGLIDLAIDTYRRAIEL-QPHFPDAYCNLANALKEKGSVAEAEDC 315
Query: 364 FEKVLKAYPNNYETMKILGSLYAASEDQEKRDIAKGHLKKVTEQYPDDVEAWIELAQILE 423
+ L+ P + +++ L ++ +Q + A +K E +P+ A LA +L+
Sbjct: 316 YNTALRLCPTHADSLNNLANI---KREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQ 372
Query: 424 QT-DIQGALSAYGTATRILQEKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAK 482
Q +Q AL Y A RI A +N+G + ++ A + + ++
Sbjct: 373 QQGKLQEALMHYKEAIRISPTFADA------YSNMGNTLKEMQDVQGALQCYTRAIQINP 426
Query: 483 AEAEHDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMAR 542
A A D H NLA +++ EA Y+ L+ P++ D Y L +
Sbjct: 427 AFA--DAH----------SNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLAHCLQ 474
Query: 543 DKGNFYEASDWFKEALQINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTY 602
++ + + K+ + I D + + + ++H P F + + ++ +
Sbjct: 475 IVCDWTDYDERMKKLVSIVADQLEK-NRLPSVHPHHSMLYPLSHGFRKAI------AERH 527
Query: 603 SMLALGNVWLQTLHQPTRDREKEKRHQDRALAI 635
L L + LH+P + K+ + D L +
Sbjct: 528 GNLCLDKI--NVLHKPPYEHPKDLKLSDGRLRV 558
Score = 43.9 bits (102), Expect = 0.001
Identities = 54/258 (20%), Positives = 104/258 (40%), Gaps = 16/258 (6%)
Query: 121 DKIIMYDQNHL-----LGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFN 175
+K + D N L LG L E D+A A + L+ SPN+ AC+ +
Sbjct: 215 EKAVTLDPNFLDAYINLGNV---LKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYE 271
Query: 176 KKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGAL 235
+ A+ Y++A+ P P + + + + + +A ++ AL L +L
Sbjct: 272 QGLIDLAIDTYRRAIELQPHFP-DAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSL 330
Query: 236 VGLAVLELNNKEADSIKNGVQLLSRAYTIDPSNPMVLNHLANHFFFKKDYSKVQHLALHA 295
LA ++ +E +I+ V+L +A + P ++LA+ + K+Q +H
Sbjct: 331 NNLANIK---REQGNIEEAVRLYRKALEVFPEFAAAHSNLAS---VLQQQGKLQEALMHY 384
Query: 296 FHNTEVEAMQAESCYQLARSFHVQEDYDQAFQYYYQATQFASSSFVLPFFGLGQMYIYRG 355
+ A++ + + +D A Q Y +A Q + +F L ++ G
Sbjct: 385 KEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQI-NPAFADAHSNLASIHKDSG 443
Query: 356 DKENASQCFEKVLKAYPN 373
+ A + LK P+
Sbjct: 444 NIPEAIASYRTALKLKPD 461
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 74.3 bits (181), Expect = 6e-13
Identities = 91/382 (23%), Positives = 157/382 (41%), Gaps = 48/382 (12%)
Query: 815 RQCSDLLSQAQYHVARARK-QDEEEREL---RAKQEQEKELLRQKLLKEQEEKRLREKEE 870
+Q + L++ +++ RK Q +EER + R K+E+E+ +++LKE+EE RE+ E
Sbjct: 777 KQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREE---RERAE 833
Query: 871 QKKLLEQRAQYVEKTKNI----------LMFTGETEATKEKKRGGGGGRRSKKGGEFDEF 920
+ K E+ +Y E+ K + + E E +E++R G S+K + +
Sbjct: 834 RAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDR 893
Query: 921 VNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPK 980
++ T P + + RR E+E EG + + RR + DD++ E +
Sbjct: 894 DSEGTWRKGPEADSEWRR--GPPEKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLR 951
Query: 981 PKKRRPPKAEKKKAPKPERLPP----SMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRN 1036
P R P+ P R P S +G + ++DD D +IADE R
Sbjct: 952 PDDDRVPRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDD--DRPPRRIADE--DRG 1007
Query: 1037 SNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRR-------PRRQRSDQDSDSDQ 1089
+ ++D D +R D D ++ E PRR PRR +D + S +
Sbjct: 1008 NWRHADDDRPPRR------GLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWR 1061
Query: 1090 PSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGN 1149
+ R D+ + G +D R + D RG D++ G G
Sbjct: 1062 NADDDRGPRRGLDDDRGPRRGM-------DDDRGPRRGMDDDRGPRRGMDDD-RGPRRGL 1113
Query: 1150 ESEPEGSNNEASDRGSEHGSDD 1171
+ + N DR G++D
Sbjct: 1114 DDDRGPWRNADDDRIPRRGAED 1135
Score = 47.0 bits (110), Expect = 1e-04
Identities = 82/397 (20%), Positives = 152/397 (38%), Gaps = 67/397 (16%)
Query: 835 DEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEE-QKKLLEQRAQYVEKTK------- 886
++ E EL+ ++ E+E LRQ+ + ++E+ L+E E+ +KK + +R + ++KT+
Sbjct: 595 EQREAELQKVRKAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFK 654
Query: 887 ------------NILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISK- 933
+ +M + KEKK + +K + D F +++P+ K
Sbjct: 655 DIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEK--KIDYFERAKRLEEIPLIKS 712
Query: 934 --KKKRRKGSG--SEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKA 989
+++R K +QE E + +++K H +D + K R
Sbjct: 713 AYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVY 772
Query: 990 EKKKAPKPERLPPSMKGKI-------KSKAIISSSDDSSDEDKLKIAD----EGHPRNSN 1038
E+K ERL ++ K + I+ + +E++ + + E R
Sbjct: 773 EEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERA 832
Query: 1039 SNSDSDED--------------EQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQD 1084
+ +E+ E++K+ E + E + + G R+ D
Sbjct: 833 ERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGD 892
Query: 1085 SDSDQPSRK---------RRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHE-S 1134
DS+ RK R P E E RSH ++ RP + D E S
Sbjct: 893 RDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSH---RRDEERPRRLGDDEDREPS 949
Query: 1135 ERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDD 1171
R D+ +G ++ P E DR S G+DD
Sbjct: 950 LRPDDDRVPRRGMDDDRGPRRGPEE--DRFSRRGADD 984
Score = 42.7 bits (99), Expect = 0.002
Identities = 74/389 (19%), Positives = 160/389 (41%), Gaps = 58/389 (14%)
Query: 822 SQAQYHVARARKQDEEERELRAKQ---EQEKELLRQK-----LLKEQEEKRLRE---KEE 870
S+ ++ AR+Q EER+ R + ++EKE L Q+ +++ EE+RLR+ + E
Sbjct: 561 SRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKERE 620
Query: 871 QKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLP 930
++++L++ Q +KT E ++ K+ G + K + D ++ D D
Sbjct: 621 KERILQEHEQIKKKTVR--------ERLEQIKKTELGAKAFK---DIDIEDLEELDPDFI 669
Query: 931 ISKK----KKRRKGSGSEQEGEDEEGGERKKKKRR------RHPKGEEGSDDDETENGPK 980
++K+ +K +K + ++++ ++ KR + E+ D + +
Sbjct: 670 MAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQE 729
Query: 981 PKKRRPPKAEKKKA-PKPERLPPSMKGKIKSKAIISSSDDSSDEDKLK-----IADEGHP 1034
++ + E++KA R+ ++ + + ++ S E+KLK +A+E H
Sbjct: 730 EERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHN 789
Query: 1035 RNSNSN------------SDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSD 1082
R + +E+EQR+ + +E + ++ R ++R
Sbjct: 790 RLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVK 849
Query: 1083 QDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSA--------ESDHES 1134
+ + ++ R+R E+ + S +S DSR + E+D E
Sbjct: 850 KLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEW 909
Query: 1135 ERGSDNEGSGQGSGNESEPEGSNNEASDR 1163
RG + +G G + + +E R
Sbjct: 910 RRGPPEKEWRRGEGRDEDRSHRRDEERPR 938
Score = 37.7 bits (86), Expect = 0.065
Identities = 66/325 (20%), Positives = 117/325 (36%), Gaps = 74/325 (22%)
Query: 902 KRGGGGGRRSKKGGEFDEF-----VNDDTDDDLPISKKKKRRKGSGSEQ---EGEDEEGG 953
+RG R ++GG DE +DD + + R+G ++ G D++ G
Sbjct: 1039 RRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRGPRRGMDDDRG 1098
Query: 954 ERKKKKRRRHPKGEEGSDDD-----------------ETENGP-----------KPKKRR 985
R+ R P+ G DDD E + GP + R
Sbjct: 1099 PRRGMDDDRGPR--RGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDDRLSRRADDDR 1156
Query: 986 PPKAEKKKAPKPER--LPPS---MKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSN 1040
P+ P P R + P K K + ++ + E++ ++ R++
Sbjct: 1157 FPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWDREKERDRDNQDR 1216
Query: 1041 SDSDEDEQRKKCASSESDSDENQNKSGSEAG--------------SPRRPRRQRSD--QD 1084
++D+D +R++ + D ++ + E G S RR R R D ++
Sbjct: 1217 EENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRE 1276
Query: 1085 SDSDQPSRKRRPSGSE--------QSDNESVQS-----GRSHSGVSEND--SRPASPSAE 1129
D + R+RR + +S+ E V S R V E D R P+
Sbjct: 1277 RDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALS 1336
Query: 1130 SDHESERGSDNEGSGQGSGNESEPE 1154
D E +R + EG + + +E +
Sbjct: 1337 RDRERDRDREREGEKEKASWRAEKD 1361
Score = 31.6 bits (70), Expect = 4.6
Identities = 33/154 (21%), Positives = 62/154 (40%), Gaps = 17/154 (11%)
Query: 830 RARKQDEEERELRAKQE--------QEKELLRQKLLKEQEEK--RLREKEEQKKLLEQRA 879
R R D E+R R + E +E R ++ ++ R RE+++++ L E+R
Sbjct: 1229 RERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRD 1288
Query: 880 QYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRK 939
++ + E E +R +K +E D P + + R +
Sbjct: 1289 LRDDRDRRGPPLRSEREEVSSWRRAD-----DRKDDRVEE--RDPPRRVPPPALSRDRER 1341
Query: 940 GSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDD 973
E+EGE E+ R +K R + + +D+D
Sbjct: 1342 DRDREREGEKEKASWRAEKDRESLRRTKNETDED 1375
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 74.3 bits (181), Expect = 6e-13
Identities = 76/297 (25%), Positives = 111/297 (37%), Gaps = 52/297 (17%)
Query: 894 ETEAT----KEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGED 949
ETE T KK G R KK + + S K KR+ + +E++
Sbjct: 654 ETEDTGRSLPSKKERSGKSHRHKKKKKHKK------------SSKHKRKHKADTEEKSSK 701
Query: 950 EEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIK 1009
E GE+ KK+++R K + S ++E GPKP+ PP + P+ R
Sbjct: 702 AESGEKSKKRKKRKRKKNKSSAPADSERGPKPE---PPGSGSPAPPRRRR---------- 748
Query: 1010 SKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSE 1069
+ D S L + + S + + E Q ++G++
Sbjct: 749 ------RAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTK 802
Query: 1070 AGSPRRPRRQRSDQDSDSDQPSRKR--RPSGSEQSDNESVQSGRSHSGVSENDSRPASPS 1127
S R Q S D DSD S R + S S+ S+ E + SG + SR S
Sbjct: 803 RSSRSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEED----SGSEHSRSRSRSGR 858
Query: 1128 AESDHESERGSDNEGSGQGSGNE------SEPEGSNNEASDRGSEHG-----SDDSD 1173
S H S R S + S S S + S ++ SDR H SDDSD
Sbjct: 859 RHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSD 915
Score = 63.5 bits (153), Expect = 1e-09
Identities = 55/226 (24%), Positives = 84/226 (37%), Gaps = 29/226 (12%)
Query: 961 RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDS 1020
++ P G GS+ ++T KK R K+ + K K + S K K K KA
Sbjct: 644 KQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHK--KSSKHKRKHKA-------- 693
Query: 1021 SDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR 1080
E+K A+ G +++K +S+ +DS+ +GSP PRR+R
Sbjct: 694 DTEEKSSKAESGEKSKKRKKR-----KRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRR 748
Query: 1081 SDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASP---------SAESD 1131
QD + S ++ + S + H G P S S+ S
Sbjct: 749 RAQDDSQRRSLPAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSS 808
Query: 1132 HESERGSDNEGSGQGSGNESEPE-----GSNNEASDRGSEHGSDDS 1172
H S+ S +E S S + + E D GSEH S
Sbjct: 809 HRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRS 854
Score = 62.8 bits (151), Expect = 2e-09
Identities = 82/400 (20%), Positives = 145/400 (36%), Gaps = 60/400 (15%)
Query: 830 RARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKK------------LLEQ 877
R K D EE+ +A+ ++ + +++ K+ + + E K +
Sbjct: 689 RKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRR 748
Query: 878 RAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKR 937
RAQ + +++ E ++ +K GGGG GG + + K+
Sbjct: 749 RAQDDSQRRSL---PAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSS 805
Query: 938 RKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKP 997
R S+ DE+ + + + + +++E ++G + + R + + +
Sbjct: 806 RSSHRSQPSSGDEDSDDASSHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRS 865
Query: 998 ERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDE--------QR 1049
R S S S S +D + R+S + DSD+ + +R
Sbjct: 866 SRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKR 925
Query: 1050 KKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQS 1109
K +SS+ D + ++S S + S R R RS S S SR R S + S Q
Sbjct: 926 HKYSSSDDDYSLSCSQSRSRSRSHTR-ERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQR 984
Query: 1110 GRSHSGVSENDSRPASPSAES-----DHES--ERGSDNE------------------GSG 1144
RS+S +R S + S HES ER S G G
Sbjct: 985 SRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEERHSGRRDFIRSKIYRSQSPHYFRSGRG 1044
Query: 1145 QGSGNESEPEGSNNEAS-----------DRGSEHGSDDSD 1173
+G G + + G +++A+ RGSE D
Sbjct: 1045 EGPGKKDDGRGDDSKATGPPSQNSNIGTGRGSEGDCSPED 1084
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 73.2 bits (178), Expect = 1e-12
Identities = 81/312 (25%), Positives = 121/312 (38%), Gaps = 33/312 (10%)
Query: 827 HVARARKQDEEERELRAKQEQEKELLRQKLLKEQ---EEKRLREKEEQKKLLEQRAQYVE 883
H ++ EEE E R K +++Q+ LK+Q E++ +EK ++K E R +E
Sbjct: 152 HRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLE 211
Query: 884 KTKNILMFTGET---------EATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKK 934
+ + +A K+ GG ++ KK G DE D D D +
Sbjct: 212 DDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEV 271
Query: 935 KKRRKGSGSEQEGEDEEGGERKKKKRRRHPKG-EEGSDDDETENGPKPKKRRPPKAEKKK 993
GS S QE E + K ++ PKG +E SD E KP + + E+KK
Sbjct: 272 DYMSDGSSSSQE---EPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKK 328
Query: 994 APKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHP--RNSNSNSDSDEDEQRKK 1051
AP P+ +S + S DS L +A + P R + S R
Sbjct: 329 APTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPG 388
Query: 1052 CASSESDSDEN----------QNKSGSEAGSPRRPRRQRSDQD----SDSDQPSRKRRP- 1096
S+E S + Q K SE + +R R Q S PS K P
Sbjct: 389 TPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPN 448
Query: 1097 SGSEQSDNESVQ 1108
SG Q ++V+
Sbjct: 449 SGDVQVTEDAVR 460
Score = 53.5 bits (127), Expect = 1e-06
Identities = 55/251 (21%), Positives = 101/251 (40%), Gaps = 36/251 (14%)
Query: 931 ISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAE 990
I ++++ + E E E E+ G RK + R H ++ + + + R PKA
Sbjct: 176 IMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKA- 234
Query: 991 KKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRK 1050
KKKAP L + K K K + + SD+ + + + + +S+S + + + K
Sbjct: 235 KKKAP----LAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAK 290
Query: 1051 KCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPS---RKRRPSGSEQSDNESV 1107
E ++ SE +P + +++ + P+ +KRR SE+SD+
Sbjct: 291 APQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDS--- 347
Query: 1108 QSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGS--GNESEPEGSNNEASDR-- 1163
S ESD +SE S + + + E +P G ++ + R
Sbjct: 348 -------------------SEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPG 388
Query: 1164 --GSEHGSDDS 1172
+E GS S
Sbjct: 389 TPSAEGGSTSS 399
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 72.4 bits (176), Expect = 2e-12
Identities = 89/384 (23%), Positives = 159/384 (41%), Gaps = 61/384 (15%)
Query: 832 RKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKN-ILM 890
+K +++ERE R K+++EK LR+ LKE+EE +K++ K+ QR E K+ + +
Sbjct: 231 KKAEKKERE-RKKRDEEKAKLRK--LKEKEELETGKKDQSKQKESQRKFEEETVKSKVTV 287
Query: 891 FTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDE 950
TG A++EK E DD + D K KK++KG E+E E +
Sbjct: 288 DTGVIPASEEK-------------AETPTAAEDDNEGDKK-KKDKKKKKGEKEEKEKEKK 333
Query: 951 EGGER--------------KKKKRRRHPKGEEGSDDDETENGPKPKKR-RPPKAEKKKAP 995
+G + ++++R++ + E +E E K ++R K E+KK
Sbjct: 334 KGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQK 393
Query: 996 KPERLPPSMK-GKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSD---EDEQRKK 1051
+ ER K GK+ +K+ + + KL A + +S ED++RKK
Sbjct: 394 EKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453
Query: 1052 CASSESDSDENQNKS------GSEAGSPRR---PRRQRSDQDSDSDQPSRKRRPSGSEQS 1102
+ +++ E G P + P +++ D++ + +
Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDE 513
Query: 1103 DNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSN-NEAS 1161
+ E V+ + H V EN E + + E + E G+ G+E + E ++
Sbjct: 514 ETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEK 573
Query: 1162 DRG--------------SEHGSDD 1171
D G SE+ SDD
Sbjct: 574 DSGKTLDKKPSKEMSSDSEYDSDD 597
Score = 59.7 bits (143), Expect = 2e-08
Identities = 62/278 (22%), Positives = 122/278 (43%), Gaps = 33/278 (11%)
Query: 829 ARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLE-QRAQYVEKTKN 887
A A+ ++EEER+ R ++E+ K L + +++EE+ +EK E+KK E +R + ++K
Sbjct: 347 ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK 406
Query: 888 ILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEG 947
+L T++ +E + + + + D PI + KKR+K Q+
Sbjct: 407 LL-----TKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK---IPQQL 458
Query: 948 EDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGK 1007
E +E E E + + E G K+ PP E P +
Sbjct: 459 ESKEVSESM----------ELCAAVEVMEQGVPEKEETPPPVE-----------PEEEED 497
Query: 1008 IKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSG 1067
+ + +SDE+ K+ EG+ + + +E+E+ ++ + +S+E + + G
Sbjct: 498 TEDAGLDDWEAMASDEETEKV--EGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEG 555
Query: 1068 SEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNE 1105
GS ++ + DS + + ++PS SD+E
Sbjct: 556 ESEGSEGDEEDEKVSDEKDSGK-TLDKKPSKEMSSDSE 592
Score = 58.5 bits (140), Expect = 4e-08
Identities = 69/342 (20%), Positives = 135/342 (39%), Gaps = 49/342 (14%)
Query: 829 ARARKQDEEERELRAKQEQEKELL-RQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKN 887
A+ K D E ++ + E+E + K K Q+ K+ + + LE + +KT
Sbjct: 69 AQGIKADRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAK 128
Query: 888 --ILMFTG---ETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSG 942
+ M++G + + K K+ G ++S K + E +D D+ I K++ R SG
Sbjct: 129 PKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSE---EDEDNSKKI-KERSRINSSG 184
Query: 943 SEQEGEDE----EGGERKKKKRRRHPKGEEGSDDDETENGPKP-------------KKRR 985
+ DE G++K +K + P E G++DD+ K KKR
Sbjct: 185 ESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRD 244
Query: 986 PPKAEKKKAPKPERLPPSMKGK--------------IKSKAIISSSDDSSDEDKLKIADE 1031
KA+ +K + E L K + +KSK + + + E+K +
Sbjct: 245 EEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAET--- 301
Query: 1032 GHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPS 1091
P + +++ D+ ++ KK E + E + K G + + + + ++
Sbjct: 302 --PTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKL---KEEEE 356
Query: 1092 RKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHE 1133
R++R E +++ R E + R E + +
Sbjct: 357 RQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERK 398
Score = 57.4 bits (137), Expect = 8e-08
Identities = 55/244 (22%), Positives = 109/244 (44%), Gaps = 36/244 (14%)
Query: 908 GRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGE 967
G++ K E D T DD+ + +G+G+ +E E ++ +KKK++++ E
Sbjct: 2 GKKQKNKSE------DSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFDE 55
Query: 968 EGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLK 1027
DD E + + KA+++ + K ++ ++ + +DK K
Sbjct: 56 ---DDILKELEELSLEAQGIKADRE--------------TVAVKPTENNEEEFTSKDKKK 98
Query: 1028 IADEGHPRNSNSNSD---SDEDEQRKKCAS------SESDSDENQNKSGSEAGSPRRPRR 1078
+G ++ + N D+D + KK A S SD D++ NK +A +
Sbjct: 99 KGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSN 158
Query: 1079 QR---SDQDSDSDQPSRKR-RPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHES 1134
++ S++D D+ + ++R R + S +S +ES + +S G +N P+ ES +E
Sbjct: 159 KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNED 218
Query: 1135 ERGS 1138
+ S
Sbjct: 219 DDAS 222
Score = 56.6 bits (135), Expect = 1e-07
Identities = 67/302 (22%), Positives = 130/302 (43%), Gaps = 32/302 (10%)
Query: 830 RARKQDEEERELRAKQEQEKELLRQKL-----LKEQEEKRLREKEEQKKLLEQRAQYVEK 884
+ +K ++EE+E K+ K ++ LKE+EE++ RE+EE+ K LE+ ++
Sbjct: 319 KKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKE 378
Query: 885 TKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSE 944
+ + E + KEK+R R KK G+ + K + G E
Sbjct: 379 EERLEQEKRERKKQKEKERK----ERLKKEGKL--LTKSQREARARAEATLKLLQAQGVE 432
Query: 945 QEGEDEEGGER---KKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLP 1001
+D +R + KKR++ P+ E + E+ + + ++ P+ E P
Sbjct: 433 VPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESM-----ELCAAVEVMEQGVPEKEETP 487
Query: 1002 PSMKGKIKSKAIISSSDD----SSDEDKLKIADEGHP-----RNSNSNSDSDEDEQRKKC 1052
P ++ + + + DD +SDE+ K+ EG+ + + + +E+E+ +
Sbjct: 488 PPVEPEEEEDTEDAGLDDWEAMASDEETEKV--EGNKVHIEVKENPEEEEEEEEEEEEDE 545
Query: 1053 ASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSE-QSDNESVQSGR 1111
S E + +E +++ GSE D D+ K S SE SD++ + R
Sbjct: 546 ESEEEEEEEGESE-GSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEER 604
Query: 1112 SH 1113
++
Sbjct: 605 AY 606
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/338 (21%), Positives = 136/338 (40%), Gaps = 46/338 (13%)
Query: 831 ARKQDEEERELRAKQEQEKELLRQK-LLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNIL 889
A++Q+ ++ + + K+E++K+ + +LKE EE L E Q ++ V+ T+N
Sbjct: 32 AKEQEPQKSKGKKKKEKKKQDFDEDDILKELEELSL---EAQGIKADRETVAVKPTEN-- 86
Query: 890 MFTGETEATKE--KKRGGGGGRRSKKGGEFDEFVN-------------------DDTDDD 928
E E T + KK+G G ++S + +E + DD DD
Sbjct: 87 ---NEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDF 143
Query: 929 LPISKK------KKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDE---TENGP 979
+ KK K +K GSE EDE+ ++ K++ R + GE G + DE + G
Sbjct: 144 NKLPKKAKGKAQKSNKKWDGSE---EDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQ 200
Query: 980 KPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSD-DSSDEDKLKI--ADEGHPRN 1036
K ++ P + + + +K + KA + DE+K K+ E
Sbjct: 201 KKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELE 260
Query: 1037 SNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSR-KRR 1095
+ S + E ++K S + A + ++ D++ D+ + K++
Sbjct: 261 TGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKK 320
Query: 1096 PSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHE 1133
G ++ + + G S + V A E + +
Sbjct: 321 KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQ 358
Score = 34.7 bits (78), Expect = 0.55
Identities = 45/206 (21%), Positives = 86/206 (41%), Gaps = 11/206 (5%)
Query: 835 DEEERELRAKQEQEKELLRQKLL---KEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMF 891
++++R+ +Q + KE+ L E E+ + EKEE +E + E T++ +
Sbjct: 447 EDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEE--EDTEDAGLD 504
Query: 892 TGETEATKEKKRGGGGGRR----SKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEG 947
E A+ E+ G + + E +E ++ +D+ ++++ + GSE +
Sbjct: 505 DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDE 564
Query: 948 EDEEGGERKK--KKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMK 1005
EDE+ + K K + P E SD + + + K+ R K++ K
Sbjct: 565 EDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRLEHSKNV 624
Query: 1006 GKIKSKAIISSSDDSSDEDKLKIADE 1031
K +A I D K KI D+
Sbjct: 625 NTEKLRAPIICVLGHVDTGKTKILDK 650
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 72.0 bits (175), Expect = 3e-12
Identities = 51/170 (30%), Positives = 92/170 (54%), Gaps = 8/170 (4%)
Query: 832 RKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLRE--KEEQKKLLEQRAQYVEKTKNIL 889
RK++ ERE R K+E+EKE R++ KE+++++ RE KE ++K E+ Q E+ +
Sbjct: 36 RKKERREREKR-KREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKER 94
Query: 890 MFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGED 949
+ + +E+K+ G R+ KK + E N + +KK+R+K E++ E
Sbjct: 95 RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER---KRKKRRKKKRRKERKREK 151
Query: 950 EEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPER 999
E G +K+K+R+ + E+ + + E K ++ R + E+KK K ER
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRKER--KKERERKERRERKKERKKER 199
Score = 57.4 bits (137), Expect = 8e-08
Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 21/164 (12%)
Query: 830 RARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVE------ 883
+ R++ +ERE + K+ +EKE ++K K++ E++ R + E+KK E++ + E
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 884 -KTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSG 942
K K E +EK+RG +R K+ E E KK+ R
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE--------------KKRERNRKE 178
Query: 943 SEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRP 986
++E E +E ERKK++++ K +E D +T+ + RP
Sbjct: 179 RKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRP 222
Score = 47.0 bits (110), Expect = 1e-04
Identities = 40/182 (21%), Positives = 75/182 (41%), Gaps = 8/182 (4%)
Query: 933 KKKKRRKGSGSEQEGEDEEGGER-----KKKKRRRHPKGEE--GSDDDETENGPKPKKRR 985
+KK+RR+ ++E E E ER KK+K+R K E + ++ + K+RR
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Query: 986 PPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDE 1045
K EKKK + +R K K + K + + + K + + + +
Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK 155
Query: 1046 DE-QRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDN 1104
E +RKK E + +N+ + R+ RR+R + + ++R+
Sbjct: 156 RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQT 215
Query: 1105 ES 1106
+S
Sbjct: 216 DS 217
Score = 44.3 bits (103), Expect = 7e-04
Identities = 35/200 (17%), Positives = 69/200 (34%), Gaps = 12/200 (6%)
Query: 954 ERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAI 1013
ERKK++R R + E + + E G K KK+R + K+ + K K
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERER------------KRKER 82
Query: 1014 ISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSP 1073
+ ++++ K E R + +++++ + + K
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
Query: 1074 RRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHE 1133
RR R+R + ++ +KR+ E+ + + + E R E +
Sbjct: 143 RRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKK 202
Query: 1134 SERGSDNEGSGQGSGNESEP 1153
ER D + Q P
Sbjct: 203 KERKKDRKTDRQTDSQVFRP 222
Score = 43.1 bits (100), Expect = 0.002
Identities = 39/211 (18%), Positives = 82/211 (38%), Gaps = 17/211 (8%)
Query: 931 ISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAE 990
ISK +R+ ++ E E+ ++K+R+R +E + E G + +++R + +
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 991 KKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRK 1050
++K ER + + K K E K K + R + + ++RK
Sbjct: 85 QRK----ERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRK 140
Query: 1051 KCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSG 1110
K + K E G R R++R ++ + K+R ++ E +
Sbjct: 141 K-------KRRKERKREKERGKRERKRKKRKKEERE------KKRERNRKERKKERERKE 187
Query: 1111 RSHSGVSENDSRPASPSAESDHESERGSDNE 1141
R R + D +++R +D++
Sbjct: 188 RRERKKERKKERRKKKERKKDRKTDRQTDSQ 218
Score = 40.8 bits (94), Expect = 0.008
Identities = 44/241 (18%), Positives = 92/241 (38%), Gaps = 52/241 (21%)
Query: 859 EQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFD 918
++E +R +E+ E++K +R EK+R G++ KK
Sbjct: 31 QRESERKKERREREKRKRER---------------------EKERKRERGKKEKK----- 64
Query: 919 EFVNDDTDDDLPISKKKKRRKGSGSEQ---EGEDEEGGERKKKKRRRHPKGEEGSDDDET 975
K+KKR +G E+ E E + R+K++R+R +E +
Sbjct: 65 --------------KRKKRERGKERERKRKEREKQRKERREKERRKRK---KEKKKRERK 107
Query: 976 ENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPR 1035
+ G + +K++ + E+++ K R K + K + +K + E +
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR------KERKREKERGKRERKRK 161
Query: 1036 NSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRR 1095
+ E+ +K E + E + + R+ + ++ D+ +D S+ R
Sbjct: 162 KRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFR 221
Query: 1096 P 1096
P
Sbjct: 222 P 222
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 70.5 bits (171), Expect = 9e-12
Identities = 71/370 (19%), Positives = 151/370 (40%), Gaps = 32/370 (8%)
Query: 809 LAATEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREK 868
L + E + D + + + K+ +E + R ++E+E+E R++ +E+E +R RE+
Sbjct: 276 LISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERERERER 335
Query: 869 EEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDD 928
E++K+ +R + ++ + T E + ++++R R D + + D
Sbjct: 336 EKEKERERERERDRDRDR-----TKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRD 390
Query: 929 LPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPK 988
++++R + E+E E E ER++++ R K ++ D +E E +++ K
Sbjct: 391 REREREREREREREREREREREREREREREREREREK-DKKRDREEDEEDAYERRKLERK 449
Query: 989 AEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED-- 1046
+K+A ERL + K + +E + ++A E R D D+D
Sbjct: 450 LREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEA-KRLKEFLEDYDDDRD 508
Query: 1047 ----------EQRKKCASSESDSDENQNKSGSEAGSPRRPR------------RQRSDQD 1084
++R + E ++DE K E R R QR +Q+
Sbjct: 509 DPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQE 568
Query: 1085 SD-SDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGS 1143
++ QP K+ P E+ + + + + + E + P + + + S
Sbjct: 569 AERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSS 628
Query: 1144 GQGSGNESEP 1153
G+ + P
Sbjct: 629 ASGNATPNTP 638
Score = 60.5 bits (145), Expect = 9e-09
Identities = 71/313 (22%), Positives = 121/313 (38%), Gaps = 60/313 (19%)
Query: 833 KQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFT 892
++ E ERE ++E+E+E +++ +E EE ++ ++KL E+ A Y E+ KN +
Sbjct: 409 REREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRE 468
Query: 893 G------ETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQE 946
E EA +E++R + +K+ EF E +DD DD +++ E+E
Sbjct: 469 RKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKE 528
Query: 947 GEDEEGGERKKKK-----------------------------RRRHPK-------GEEGS 970
E +E +++K+ RRR P+ EE
Sbjct: 529 MEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEE 588
Query: 971 DDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIAD 1030
+ E E + + E+K KP P S + S + ++ + DE I
Sbjct: 589 EKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNATPNTPGDESPCGIII 648
Query: 1031 EGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR--------SD 1082
+ NS +E R K S N G P +R++
Sbjct: 649 P----HENSPDQQQPEEHRPKIGLSLKLGASN------SPGQPNSVKRKKLPVDSVFNKF 698
Query: 1083 QDSDSDQPSRKRR 1095
+D DSD RKR+
Sbjct: 699 EDEDSDDVPRKRK 711
Score = 58.9 bits (141), Expect = 3e-08
Identities = 67/349 (19%), Positives = 138/349 (39%), Gaps = 23/349 (6%)
Query: 831 ARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILM 890
A + +E++R+L +++ + +KL +EEK +EKE Q+ E+R + E+ +
Sbjct: 266 AIEMEEDKRDLISREISKFRDTHKKL---EEEKGKKEKERQEIEKERRERERERERERER 322
Query: 891 FTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDE 950
E E +E++R R ++ + D D +K++ R + +++ + E
Sbjct: 323 REREREREREREREKEKERERER----------ERDRDRDRTKERDRDRDRERDRDRDRE 372
Query: 951 EGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKS 1010
+R K + R K + + E E + ++ R + E+++ + ER K K +
Sbjct: 373 RSSDRNKDRSRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRD 432
Query: 1011 KAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEA 1070
+ +D+ + KL+ + E +RKK E +++ + + A
Sbjct: 433 RE--EDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMA 490
Query: 1071 GSPRRPRRQRSDQDSDSDQPS-------RKRRPSGSEQSDNESVQSGRSHSGVSENDSR- 1122
+R + D D D D P +KR ++ + + R + E R
Sbjct: 491 KEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRL 550
Query: 1123 PASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDD 1171
A + D E +R + + EPE E + E ++
Sbjct: 551 LAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREE 599
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 70.5 bits (171), Expect = 9e-12
Identities = 90/396 (22%), Positives = 156/396 (39%), Gaps = 75/396 (18%)
Query: 827 HVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEE---QKKLLEQRAQYVE 883
H R+ + EE++ L K L+ ++LLK Q ++ +++ KK +
Sbjct: 36 HSGRSHLEPEEKQAL-------KRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSD 88
Query: 884 KTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGS 943
+ F E+E+ E G +K G ++ +K++ R+ S +
Sbjct: 89 PERKRFRFNSESESGSEASSPDYFGPPAKNG----------VAAEVSPAKEENPRRASKA 138
Query: 944 EQEGEDEEGGERKKKKRRRHPKGEEGSDDDE------TENGPKPKKRRPPKA-------- 989
+E DEE +++ +GEE S+++E T P KK+ P KA
Sbjct: 139 VEESSDEE-----RQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAR 193
Query: 990 ---EKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED 1046
E+ +A +R ++G +K++ S +S +E + ++ + DE+
Sbjct: 194 EESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEE 253
Query: 1047 EQ----------RKKCASSE---------------SDSDENQNK---SGSEAGSPRRPRR 1078
+ R+K A E SDS+E Q + SG ++G R P
Sbjct: 254 KGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPV 313
Query: 1079 QRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGS 1138
QR + D Q +R SGS + + +S + + G S +R S S E S
Sbjct: 314 QRKSE--DRTQLKGGKRLSGSSEDEEDSGKGEPTAKG-SRKMARLGSTSGEESDLEREVS 370
Query: 1139 DNEGSG--QGSGNESEPEGSNNEASDRGSEHGSDDS 1172
D+E G QG + S+ + R S SD S
Sbjct: 371 DSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGS 406
Score = 67.4 bits (163), Expect = 8e-11
Identities = 60/239 (25%), Positives = 112/239 (46%), Gaps = 48/239 (20%)
Query: 843 AKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKK 902
++QE E+E+L QK KEQ E+ + E+E+++ E++ + +T++ G ++ +E+
Sbjct: 223 SEQESEEEILAQK--KEQREEEVEEEEKEED--EEKGDWKPRTRS----NGRRKSAREE- 273
Query: 903 RGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRR 962
R K+ + + D S+++++ S + G D E ++K + R
Sbjct: 274 ------RSCKQKSQAKRLLGDSD------SEEEQKEAASSGDDSGRDREPPVQRKSEDRT 321
Query: 963 HPKGEE---GSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDD 1019
KG + GS +DE ++G K E P+ KG K + S+S +
Sbjct: 322 QLKGGKRLSGSSEDEEDSG---------KGE-----------PTAKGSRKMARLGSTSGE 361
Query: 1020 SSDEDKLKIADE---GHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRR 1075
SD ++ +++D G P+ N S + ++ + SS S SD + G +AGS RR
Sbjct: 362 ESDLER-EVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSGRR 419
Score = 63.5 bits (153), Expect = 1e-09
Identities = 68/320 (21%), Positives = 134/320 (41%), Gaps = 55/320 (17%)
Query: 835 DEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGE 894
+E +R+L A++ +E E+EEK + K +K +++++A G+
Sbjct: 145 EERQRDLPAQRGEESS--------EEEEKGYKGKTRKKPVVKKQAP------------GK 184
Query: 895 TEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGE 954
++++ R +E + + +KK + KG+ S +E E E E
Sbjct: 185 ASVSRKQAR--------------EESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEE 230
Query: 955 --RKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKA 1012
+KK++R EE ++DE + KP+ R ++K+ + ER S K K ++K
Sbjct: 231 ILAQKKEQREEEVEEEEKEEDEEKGDWKPRTR---SNGRRKSAREER---SCKQKSQAKR 284
Query: 1013 IISSSDDSSDEDKLKIA--DEGHPRNSNSNSDSDEDEQ----RKKCASSESDSDENQNKS 1066
++ SD ++ + + D G R S++ Q ++ SSE + D + +
Sbjct: 285 LLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEP 344
Query: 1067 GSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ------SDNESVQSGRSHSGVSEND 1120
++ S ++SD ++ G Q S +S + GR+ S S +D
Sbjct: 345 TAKGSRKMARLGSTSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSD 404
Query: 1121 SRPASPSAESDHESERGSDN 1140
P + ++ RG D+
Sbjct: 405 GSPEAKGGKAG-SGRRGEDH 423
Score = 43.9 bits (102), Expect = 0.001
Identities = 56/229 (24%), Positives = 99/229 (43%), Gaps = 50/229 (21%)
Query: 812 TEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQ 871
T++ + S+ S+ + + +++EE E ++++EK + + K RE+
Sbjct: 217 TKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERSC 276
Query: 872 KKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPI 931
K Q++Q K +L G++++ +E+K G S + D + P+
Sbjct: 277 K----QKSQ----AKRLL---GDSDSEEEQKEAASSGDDSGR------------DREPPV 313
Query: 932 SKKKKRR---KG----SGSEQEGEDEEGGERKKKKRRRHPK-----GEEGS---DDDETE 976
+K + R KG SGS ++ ED GE K R+ + GEE + ++E
Sbjct: 314 QRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVSDSE 373
Query: 977 NGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDK 1025
G P+ R ++ KK S KG+ +S SSS D S E K
Sbjct: 374 AGGGPQGERKNRSSKKS---------SRKGRTRSS---SSSSDGSPEAK 410
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 69.3 bits (168), Expect = 2e-11
Identities = 54/177 (30%), Positives = 87/177 (49%), Gaps = 22/177 (12%)
Query: 832 RKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMF 891
RK++ ERE R K+E+EKE R++ KE++ +R +E+ E+KK ++
Sbjct: 59 RKKERREREKR-KREREKERKRERGKKEKKGERKKEERERKKRRREKENK---------- 107
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKK---------KRRKGSG 942
GE + ++KK GR SK+G E + ++ +KK K RK
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167
Query: 943 SEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPER 999
+Q GE EE ERK+K+R+ K E + + E K ++ R + +KK+ K ER
Sbjct: 168 RKQVGEKEE--ERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKER 222
Score = 60.5 bits (145), Expect = 9e-09
Identities = 55/271 (20%), Positives = 114/271 (42%), Gaps = 53/271 (19%)
Query: 827 HVARARKQDEEERELRAKQEQEKEL-LRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKT 885
H+++ Q + E+R E+E+E+ R++ KE+E +R +E+ E++K +R
Sbjct: 24 HISKPCTQPGWQSEIR---EREREIETRKEGKKERESERKKERREREKRKRER------- 73
Query: 886 KNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQ 945
EK+R G++ KKG +KK+ R+ +
Sbjct: 74 --------------EKERKRERGKKEKKG-----------------ERKKEERERKKRRR 102
Query: 946 EGEDEEGGERKK-KKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSM 1004
E E++EG E++K KK+ + +G + E E + K+ + E+KK + +
Sbjct: 103 EKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKE 162
Query: 1005 KGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQN 1064
+ K + K + ++ +++ R + + E++K+ E + +
Sbjct: 163 RKKRERKQVGEKEEERKEKE----------RKERKKRERNRKERKKERERKERRERKKER 212
Query: 1065 KSGSEAGSPRRPRRQRSDQDSDSDQPSRKRR 1095
K E R+ RQ + ++ + + RK R
Sbjct: 213 KKKEERKKERQKDRQTNWREKERGKRERKER 243
Score = 57.0 bits (136), Expect = 1e-07
Identities = 37/174 (21%), Positives = 74/174 (42%), Gaps = 7/174 (4%)
Query: 933 KKKKRRKGSGSEQEGEDEEGGERKK-----KKRRRHPKGEEGSDDDETENGPKPKKRRPP 987
K+K+ R+ + G+ E+ GERKK KKRRR + +EG + ++ + K ++ R
Sbjct: 68 KRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTS 127
Query: 988 KAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDE 1047
K K++ K ER K + + K + + K + G + + E
Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG--EKEEERKEKERKE 185
Query: 1048 QRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQ 1101
++K+ + + E + K E R+ + +R + Q + + + G +
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRE 239
Score = 56.6 bits (135), Expect = 1e-07
Identities = 57/245 (23%), Positives = 108/245 (44%), Gaps = 39/245 (15%)
Query: 836 EEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGET 895
E ERE+ ++E +KE ++ KE+ E+ R++E +K+ +R + +K + +
Sbjct: 40 EREREIETRKEGKKERESERK-KERREREKRKREREKERKRERGKKEKKGER------KK 92
Query: 896 EATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGER 955
E + KKR RR K+ N + ++ KK+K+ +G S++ E E ER
Sbjct: 93 EERERKKR-----RREKE--------NKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139
Query: 956 KKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIIS 1015
K+++R+ E ++ E E K +K+R E+K+ + E + K + K +
Sbjct: 140 KREERKER---ERKKEEREKERERKERKKR----ERKQVGEKEEERKEKERKERKKRERN 192
Query: 1016 SSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRR 1075
+ + ++ + + R + E+RKK E D N E G R
Sbjct: 193 RKERKKERERKERRERKKERK--------KKEERKK----ERQKDRQTNWREKERGKRER 240
Query: 1076 PRRQR 1080
R++
Sbjct: 241 KERKK 245
Score = 50.8 bits (120), Expect = 7e-06
Identities = 40/164 (24%), Positives = 81/164 (49%), Gaps = 33/164 (20%)
Query: 830 RARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNIL 889
+ +K++++ER +K+ +E+E +++ +E+ ++R R+KEE++K E++ + + K +
Sbjct: 114 KRKKKEKKERGRTSKEGKERER-KEERKREERKERERKKEEREKERERKERKKRERKQV- 171
Query: 890 MFTGE-TEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGE 948
GE E KEK+R +KK+ R ++E E
Sbjct: 172 ---GEKEEERKEKERK---------------------------ERKKRERNRKERKKERE 201
Query: 949 DEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKK 992
+E ERKK+++++ + +E D +T K + +R K KK
Sbjct: 202 RKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 49.7 bits (117), Expect = 2e-05
Identities = 37/181 (20%), Positives = 79/181 (43%), Gaps = 3/181 (1%)
Query: 931 ISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAE 990
I +K+ +K SE++ E E E++K++R + K E G + + E + ++R+ + E
Sbjct: 45 IETRKEGKKERESERKKERRER-EKRKREREKERKRERGKKEKKGERKKEERERKKRRRE 103
Query: 991 KKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRK 1050
K+ E+ K K K + +S + E K + E + +++ +RK
Sbjct: 104 KENKEGEEK--EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERK 161
Query: 1051 KCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSG 1110
+ E + + E R +R+R+ ++ ++ ++RR E+ E +
Sbjct: 162 ERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKE 221
Query: 1111 R 1111
R
Sbjct: 222 R 222
Score = 45.8 bits (107), Expect = 2e-04
Identities = 44/226 (19%), Positives = 84/226 (37%), Gaps = 26/226 (11%)
Query: 945 QEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSM 1004
Q G E ER+++ R +EG + E+E + ++R K E++K K ER
Sbjct: 31 QPGWQSEIREREREIETR----KEGKKERESERKKERREREKRKREREKERKRERGKKEK 86
Query: 1005 KGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSE-----SDS 1059
KG E K + + R N + +E E+RKK E +
Sbjct: 87 KG----------------ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEG 130
Query: 1060 DENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGS-EQSDNESVQSGRSHSGVSE 1118
E + K + + R++ +++ + ++ RK+R + + E + R E
Sbjct: 131 KERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRE 190
Query: 1119 NDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRG 1164
+ + E ER + + + + +N +RG
Sbjct: 191 RNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Score = 31.6 bits (70), Expect = 4.6
Identities = 14/61 (22%), Positives = 35/61 (57%)
Query: 813 EARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQK 872
E +Q + + + + RK+ E R+ R K+ + KE +K ++++E+R +E+++ +
Sbjct: 167 ERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226
Query: 873 K 873
+
Sbjct: 227 Q 227
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 68.9 bits (167), Expect = 3e-11
Identities = 79/354 (22%), Positives = 138/354 (38%), Gaps = 30/354 (8%)
Query: 837 EERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVE-KTKNILMFTGET 895
EE K E EK + + L EE + KEE+K+ E++ + E + + +
Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 513
Query: 896 EATKEKKRGGGGGRRSKKGGEF----DEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
+AT + + G + ++G E DE D ++ K+ K G ++EGE E
Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573
Query: 952 GGERKKKKRRRHPKGEEGSDDDETENG-------PKPKKRRPPKA-----EKKKAPKPER 999
E ++ + + K EE S++ T+ KP+K + P EK K+P P+
Sbjct: 574 EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS 633
Query: 1000 LPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDS 1059
P KGK S S E+K K P S + +K S S
Sbjct: 634 -PVEEKGK-------SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 685
Query: 1060 DENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEN 1119
+ KS +E G Q+ +++ + + ++ + E+ + + ++ S V E
Sbjct: 686 PVEEAKSKAEVGKGE----QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 741
Query: 1120 DSRPASPSAESDH-ESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
+S E+ + EG E E G + + GS+ G+ S
Sbjct: 742 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGS 795
Score = 68.6 bits (166), Expect = 3e-11
Identities = 104/520 (20%), Positives = 199/520 (38%), Gaps = 49/520 (9%)
Query: 673 VREATADISDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARALFKCGK 732
+R A +I++ L +E + + E L + N ++ Y +
Sbjct: 310 IRSAKEEIAEYRRQLQSKSIELESVRGTKESLERQLSDIEERHNHDLSSYQDTIQQLENE 369
Query: 733 LQECKQTLLKARHVAPSDTVLMFNVALVLQRLA-TSVLKDEKSNLKEVLNAVKELELAHR 791
L+ K + ARH+ +L +AL ++ A +L+ E++ ++ HR
Sbjct: 370 LRGTKWEM--ARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHR 427
Query: 792 YFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKEL 851
+S K + + + + +++ + K ++E+ E+ E
Sbjct: 428 PPITISSKIQKPKVEAPKLKVQHKFVEEIIEET--------KVEDEKSEMEEALTAITEE 479
Query: 852 LRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRS 911
L + +E++E ++EE + E+ A K E E KE++ G
Sbjct: 480 LAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG------Q 533
Query: 912 KKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSD 971
++ E DE D ++ K+ K G ++EGE E E ++ + + K EE S+
Sbjct: 534 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 593
Query: 972 DDETENG-------PKPKKR-----RPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDD 1019
+ T+ KP+K + P EK K+P P + P KGK
Sbjct: 594 EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVP-KSPVEEKGKSPVPKSPVEEKG 652
Query: 1020 SSDEDKLKIADEGHPRNSNSNSD---------SDEDEQRKKCASSESDSDENQNKSGSEA 1070
S K + ++G S S + S +E + K + + E + K EA
Sbjct: 653 KSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEA 712
Query: 1071 GSPRRPRRQRSDQDSDSDQPSRKRRPSG-SEQSDNESVQSGRSHSGVSENDSRPASPSAE 1129
+ ++ ++ D P +K+ S E++ E V +S E +++ +
Sbjct: 713 PKEEKVEKK---EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQ 769
Query: 1130 SDHESER-----GSDNEGSGQGS-GNESEPEGSNNEASDR 1163
+ E E+ GS+ EGS +G+ G+ E N E +
Sbjct: 770 QEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGK 809
Score = 44.3 bits (103), Expect = 7e-04
Identities = 39/179 (21%), Positives = 86/179 (48%), Gaps = 25/179 (13%)
Query: 822 SQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQY 881
++++ V + +++EEE+E++ ++EK +++ K+ EK+ E +++ + A+
Sbjct: 690 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV---AEV 746
Query: 882 VEKTKNILMFTGET--------EATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISK 933
V TK++ + + + KEK++ GG G ++G D+ +D+ ++
Sbjct: 747 VTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGS--DKGAKGSRKEDIAVN- 803
Query: 934 KKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKK 992
E EG++E E K+K R E+G + + P +K+ K+E+K
Sbjct: 804 ---------GEVEGKEEVEQETKEKGSGREE--EKGVVTNGLDLSPADEKKGGDKSEEK 851
Score = 39.7 bits (91), Expect = 0.017
Identities = 76/416 (18%), Positives = 150/416 (36%), Gaps = 70/416 (16%)
Query: 761 LQRLATSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDL 820
+Q L V ++ +EV + + +++ +H + D ++ D++ A E R +
Sbjct: 224 VQSLQDEVAFLRSNHEEEVADLLAQIQASH----ITVERKDYLKTDISTALKEIRSQLES 279
Query: 821 LSQAQYHVAR----------ARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEE 870
S H A ++ + +R+ +E+ E RQ K E + +R +E
Sbjct: 280 HSDQNMHQAEEWFKCRYAKLTEAAEQNKEAIRSAKEEIAEYRRQLQSKSIELESVRGTKE 339
Query: 871 QKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLP 930
L Q + E+ + L +T E + G ++ E+ + +N D+
Sbjct: 340 S--LERQLSDIEERHNHDLSSYQDTIQQLENELRGTKWEMARHLREYQDLLNVKMALDIE 397
Query: 931 ISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAE 990
I+ +K +G + S + GP RPP
Sbjct: 398 IAAYRKLLEGEETRF------------------------STFAGSITGPL-YTHRPPITI 432
Query: 991 KKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRK 1050
K KP+ P +K ++ K + +++ ED+ +E + + S ++E+++
Sbjct: 433 SSKIQKPKVEAPKLK--VQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKE 490
Query: 1051 KCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSG 1110
E + + + E + + P + + + + + K G E+ + E
Sbjct: 491 AAEEKEEEPEAEEE----EVAAKKSPVKATAPEVKEEE--GEKEEEEGQEEEEEED---- 540
Query: 1111 RSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSE 1166
A+SD E GS+ EGS + E E E EA G E
Sbjct: 541 ---------------EGAKSDQAEEGGSEKEGSSE--KEEGEQEEGETEAEAEGEE 579
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 68.9 bits (167), Expect = 3e-11
Identities = 79/354 (22%), Positives = 138/354 (38%), Gaps = 30/354 (8%)
Query: 837 EERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVE-KTKNILMFTGET 895
EE K E EK + + L EE + KEE+K+ E++ + E + + +
Sbjct: 78 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPV 137
Query: 896 EATKEKKRGGGGGRRSKKGGEF----DEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
+AT + + G + ++G E DE D ++ K+ K G ++EGE E
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197
Query: 952 GGERKKKKRRRHPKGEEGSDDDETENG-------PKPKKRRPPKA-----EKKKAPKPER 999
E ++ + + K EE S++ T+ KP+K + P EK K+P P+
Sbjct: 198 EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKS 257
Query: 1000 LPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDS 1059
P KGK S S E+K K P S + +K S S
Sbjct: 258 -PVEEKGK-------SPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKS 309
Query: 1060 DENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEN 1119
+ KS +E G Q+ +++ + + ++ + E+ + + ++ S V E
Sbjct: 310 PVEEAKSKAEVGKGE----QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE 365
Query: 1120 DSRPASPSAESDH-ESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
+S E+ + EG E E G + + GS+ G+ S
Sbjct: 366 AVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGS 419
Score = 68.2 bits (165), Expect = 4e-11
Identities = 93/450 (20%), Positives = 175/450 (38%), Gaps = 47/450 (10%)
Query: 743 ARHVAPSDTVLMFNVALVLQRLA-TSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGD 801
ARH+ +L +AL ++ A +L+ E++ ++ HR +S
Sbjct: 2 ARHLREYQDLLNVKMALDIEIAAYRKLLEGEETRFSTFAGSITGPLYTHRPPITISSKIQ 61
Query: 802 KMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQE 861
K + + + + +++ + K ++E+ E+ E L + +E++
Sbjct: 62 KPKVEAPKLKVQHKFVEEIIEET--------KVEDEKSEMEEALTAITEELAVSMKEEKK 113
Query: 862 EKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFV 921
E ++EE + E+ A K E E KE++ G ++ E DE
Sbjct: 114 EAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEG------QEEEEEEDEGA 167
Query: 922 NDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENG--- 978
D ++ K+ K G ++EGE E E ++ + + K EE S++ T+
Sbjct: 168 KSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVA 227
Query: 979 ----PKPKKR-----RPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIA 1029
KP+K + P EK K+P P + P KGK S K +
Sbjct: 228 DAKVEKPEKAKSPVPKSPVEEKGKSPVP-KSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 286
Query: 1030 DEGHPRNSNSNSD---------SDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQR 1080
++G S S + S +E + K + + E + K EA + ++
Sbjct: 287 EKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKK- 345
Query: 1081 SDQDSDSDQPSRKRRPSG-SEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESER--- 1136
++ D P +K+ S E++ E V +S E +++ + + E E+
Sbjct: 346 --EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGG 403
Query: 1137 --GSDNEGSGQGS-GNESEPEGSNNEASDR 1163
GS+ EGS +G+ G+ E N E +
Sbjct: 404 EGGSEEEGSDKGAKGSRKEDIAVNGEVEGK 433
Score = 44.3 bits (103), Expect = 7e-04
Identities = 39/179 (21%), Positives = 86/179 (48%), Gaps = 25/179 (13%)
Query: 822 SQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQY 881
++++ V + +++EEE+E++ ++EK +++ K+ EK+ E +++ + A+
Sbjct: 314 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAV---AEV 370
Query: 882 VEKTKNILMFTGET--------EATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISK 933
V TK++ + + + KEK++ GG G ++G D+ +D+ ++
Sbjct: 371 VTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGS--DKGAKGSRKEDIAVN- 427
Query: 934 KKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKK 992
E EG++E E K+K R E+G + + P +K+ K+E+K
Sbjct: 428 ---------GEVEGKEEVEQETKEKGSGREE--EKGVVTNGLDLSPADEKKGGDKSEEK 475
Score = 38.1 bits (87), Expect = 0.050
Identities = 37/182 (20%), Positives = 69/182 (37%), Gaps = 29/182 (15%)
Query: 985 RPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSD 1044
RPP K KP+ P +K ++ K + +++ ED+ +E + + S
Sbjct: 51 RPPITISSKIQKPKVEAPKLK--VQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSM 108
Query: 1045 EDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDN 1104
++E+++ E + + + E + + P + + + + + K G E+ +
Sbjct: 109 KEEKKEAAEEKEEEPEAEEE----EVAAKKSPVKATAPEVKEEE--GEKEEEEGQEEEEE 162
Query: 1105 ESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRG 1164
E A+SD E GS+ EGS + E E E EA G
Sbjct: 163 ED-------------------EGAKSDQAEEGGSEKEGSSE--KEEGEQEEGETEAEAEG 201
Query: 1165 SE 1166
E
Sbjct: 202 EE 203
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 68.6 bits (166), Expect = 3e-11
Identities = 79/356 (22%), Positives = 130/356 (36%), Gaps = 26/356 (7%)
Query: 822 SQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQY 881
SQ + H +R R + RA+ K +L Q Q + K + + +R +
Sbjct: 294 SQKRTH-SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRS 352
Query: 882 VEKTKNILMFTGETEA---TKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKR- 937
++N + + +KE+ G R + G N D S K R
Sbjct: 353 HNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARD 412
Query: 938 RKGSGSEQEGEDEEGGERKKK----KRRRHPKGEEGSDDDETENGPKP--KKRRPPKAE- 990
R S S + D K R R P + N + + R P KA
Sbjct: 413 RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARD 472
Query: 991 --KKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQ 1048
+ ++P ER + K + S S + + R+ + ++ Q
Sbjct: 473 RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ 532
Query: 1049 RKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQD-----SDSDQPSRKRRPSGSEQSD 1103
R++ S + D +Q++S SE R+ R ++D S S + R++ S SE+ D
Sbjct: 533 RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERD 592
Query: 1104 NESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGS---GQGSGNESEPEGS 1156
+ +S SG S RP + S E H R EG+ + S ES+P S
Sbjct: 593 HSRSRSPNKQSGYS----RPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS 644
Score = 43.9 bits (102), Expect = 0.001
Identities = 42/219 (19%), Positives = 79/219 (36%), Gaps = 22/219 (10%)
Query: 932 SKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEK 991
SK+++ R+ S +E + K+++RR + D P ++ +
Sbjct: 504 SKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREH----RQ 559
Query: 992 KKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKK 1051
++P ER + K + S S + D H R+ + N S R
Sbjct: 560 SRSPSKERDRRRWRSPSKERERRQSRSSSEERD--------HSRSRSPNKQSGYSRPRAS 611
Query: 1052 CASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPS-GSEQSDNESVQSG 1110
+K G+ + S + Q + P KR P+ S S N +
Sbjct: 612 SKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKT 671
Query: 1111 RSHS---------GVSENDSRPASPSAESDHESERGSDN 1140
SHS +S++DS+ + ++++ ER S +
Sbjct: 672 SSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSS 710
Score = 43.5 bits (101), Expect = 0.001
Identities = 64/359 (17%), Positives = 128/359 (35%), Gaps = 34/359 (9%)
Query: 833 KQDEEERELRAKQEQEKELLRQKL---LKEQEEKRLREKEEQKKLLEQRAQYVEKTKNIL 889
+ +ER+ R KE R + K+++ R R + + R+ Y K ++
Sbjct: 369 RSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY--KARDRS 426
Query: 890 MFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGED 949
+A + R + D + P + + R S S++
Sbjct: 427 RSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHS 486
Query: 950 EEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIK 1009
+ G K++ RR + ++ + K + R + ++P ER + K
Sbjct: 487 QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR-----RSRSPSKERQRRQSRSPNK 541
Query: 1010 SKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSE 1069
+ S S + + + R+ ++ +R++ SS + D ++++S ++
Sbjct: 542 ERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNK 601
Query: 1070 AGS---PRRPRRQRSDQDSDSDQPSRKRRPS---GSEQSDNESVQSGRSHSGVSENDSRP 1123
PR ++++ SR R PS QS S +S S S V +
Sbjct: 602 QSGYSRPRASSKEKAH--------SRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWK 653
Query: 1124 ASPSAESDHESERGSDNEGS---------GQG-SGNESEPEGSNNEASDRGSEHGSDDS 1172
SP+ S R S GQ S ++S+ + + ++A+ G S S
Sbjct: 654 RSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 37.0 bits (84), Expect = 0.11
Identities = 58/257 (22%), Positives = 92/257 (35%), Gaps = 46/257 (17%)
Query: 908 GRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGE 967
G R K G N + D P + KK + G G E + + P G
Sbjct: 167 GSRGKSYGR-PRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGI 225
Query: 968 EGSDDDETENGPKPKKRRPPKAEKKKA-PKPERL--PPSMKGKIKS--KAIISSSDDSSD 1022
E + P P R K+ + P E+ P M ++KS +A S S
Sbjct: 226 PSK---EKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHS 282
Query: 1023 EDKL-KIADEGHPRNSNSNSDSDEDEQRKKCASSES-------------DSDENQNKSGS 1068
+ + + + G + ++S S ++ A S + ++ KS +
Sbjct: 283 QSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQN 342
Query: 1069 EAGSPRR---------PRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEN 1119
++ +PRR P ++RS S S R R S S + +SGRS SG
Sbjct: 343 QSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRK-----ESGRSQSG---- 393
Query: 1120 DSRPASPSAESDHESER 1136
SP+ + DH R
Sbjct: 394 -----SPNKQRDHSRSR 405
Score = 34.3 bits (77), Expect = 0.72
Identities = 50/240 (20%), Positives = 77/240 (32%), Gaps = 60/240 (25%)
Query: 986 PPKAEKKKAPKPERLP---PSMKGKIKSKAIISS--SDDSSDEDKLKIADEGHPRNSNSN 1040
P ++ K+ +R P PS + +++SKA S S D+ K +D + ++
Sbjct: 59 PSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTH 118
Query: 1041 SDSDEDEQRKKCASSESDS-------------------------DENQNKSGSEAGSPRR 1075
S +R +S S S + + G G PR
Sbjct: 119 SRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRT 178
Query: 1076 PRRQRSDQDSDSDQPSRKRRPSGS--------------------------EQSDNESVQS 1109
R+RSD + R P GS E+SDN S S
Sbjct: 179 SNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSS 238
Query: 1110 GRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGS 1169
R ++ + PS E + S S + S P+ + S R S GS
Sbjct: 239 SRK----VKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGS 294
Score = 32.3 bits (72), Expect = 2.7
Identities = 51/262 (19%), Positives = 89/262 (33%), Gaps = 38/262 (14%)
Query: 787 ELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERELRAKQE 846
E H SK D R + + ++ RQC S ++ R + +ER+ R +
Sbjct: 482 ERDHSQLGSPSKERDHRR---SRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRS 538
Query: 847 QEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGG 906
KE R + EE+ R+ K ++R +KE++R
Sbjct: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRRW--------------RSPSKERER--- 581
Query: 907 GGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKK--KKRRRHP 964
R+S+ E + D S+ ++ G + E+ R + K H
Sbjct: 582 --RQSRSSSE---------ERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHS 630
Query: 965 KGEEGSDDDETENGPKPK----KRRPPKAEKKKAPK-PERLPPSMKGKIKSKAIISSSDD 1019
+ S + + P+ KR P + + P + S S DD
Sbjct: 631 QSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDD 690
Query: 1020 SSDEDKLKIADEGHPRNSNSNS 1041
S + A R+S+S+S
Sbjct: 691 SQADATTSKATLPGERSSSSSS 712
>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
Length = 717
Score = 68.6 bits (166), Expect = 3e-11
Identities = 82/378 (21%), Positives = 151/378 (39%), Gaps = 45/378 (11%)
Query: 835 DEEERELR-----AKQEQEKELLRQKL-LKEQEEKRLREKEEQKKLLEQRA----QYVEK 884
+EEE+E+ A++EQE+E +Q++ +K +EE +RE E+Q+ + + VE
Sbjct: 336 EEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVEN 395
Query: 885 TKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSE 944
K+++ E + + SK+ EF + + +S K+ E
Sbjct: 396 VKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDME 455
Query: 945 QEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKA------PKPE 998
+E E++E E + + + + ++ +P + P ++ + P P+
Sbjct: 456 KESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQ 515
Query: 999 ------RLPPSMKG---------KIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDS 1043
L P K ++ + +++ +S + K + G RN S S S
Sbjct: 516 VTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRS 575
Query: 1044 DEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSD 1103
+SS S S + + SGS + R S S S SR S S S+
Sbjct: 576 RSSSSSSSSSSSTSSSSGSSSSSGSSSS-----RSSSSSSSSTSGSSSRDSSSSTSSSSE 630
Query: 1104 NESVQSGRSHS-----GVSENDSRPASPSAESDHESERGS---DNEGSGQGSGNESEPEG 1155
+ S GR H+ S + R + E H+S +G D +GS + + S+ +
Sbjct: 631 SRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGS-KDKNSRSDRKR 689
Query: 1156 SNNEASDRGSEHGSDDSD 1173
S +E+S G + D
Sbjct: 690 SISESSRSGKRSSRSERD 707
Score = 42.4 bits (98), Expect = 0.003
Identities = 76/396 (19%), Positives = 143/396 (36%), Gaps = 59/396 (14%)
Query: 758 ALVLQRLATSVLKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQC 817
AL +ATS + + +++ K + R F L K + + +A ++
Sbjct: 111 ALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRR 170
Query: 818 SDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQ 877
++ + + RKQ E ER +EL ++ K+ E + L +K E +L E+
Sbjct: 171 QEIEQKLEVQAEEERKQVENER---------RELFEERRAKQTELRLLEQKVELAQLQEE 221
Query: 878 ----RAQYVE----KTKNILMFTGET---------EATKEKKRGGGGGRRSKKGGEFDEF 920
A+ ++ KTK L + E ++ K GRR EF E
Sbjct: 222 WNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRI----EFAEQ 277
Query: 921 VND-DTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGP 979
+N + K+K+ + EQ+ E EEG ++++ + + E
Sbjct: 278 INKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEE 337
Query: 980 KPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIAD--------- 1030
+ K+ ++ +K + E M+ K++ + + S+ D ++ D
Sbjct: 338 EEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVK 397
Query: 1031 ------EGHPRNSNSNSDSDEDEQRK-------------KCASSESDSDENQNKSGSEAG 1071
E N + + E+E K K S S EN + E
Sbjct: 398 HVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKE 457
Query: 1072 SPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESV 1107
S + ++ Q QP + +P QS ++ V
Sbjct: 458 SEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPV 493
Score = 35.8 bits (81), Expect = 0.25
Identities = 57/308 (18%), Positives = 110/308 (35%), Gaps = 27/308 (8%)
Query: 815 RQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKL 874
++C L + A +++ EE+E + + Q + + + + Q + +L+ + + + +
Sbjct: 437 KECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQ---PQSQPQLQLQSQSQPV 493
Query: 875 LEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKK 934
L+ + + ++ + + T+E+ G R E + + L + +
Sbjct: 494 LQSQPPSQPEDLSLAVLQPTPQVTQEQ--GHLLPERKDFPVESVKLTEVPVEPVLTVHPE 551
Query: 935 KKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKA 994
K + + S G K K R S T + + + +
Sbjct: 552 SKSKTKTRSRSRGR----ARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSS 607
Query: 995 PKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCAS 1054
S S SSS SS E + + GH R+ D RK+ +
Sbjct: 608 SSSSSTSGS------SSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVD----RKRRDT 657
Query: 1055 SESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHS 1114
S + +K GS R + D++S SD RKR S S +S S +S R
Sbjct: 658 SGLERSHKSSKGGSS-----RDTKGSKDKNSRSD---RKRSISESSRSGKRSSRSERDRK 709
Query: 1115 GVSENDSR 1122
++ R
Sbjct: 710 SDRKDKRR 717
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 68.6 bits (166), Expect = 3e-11
Identities = 83/381 (21%), Positives = 147/381 (38%), Gaps = 55/381 (14%)
Query: 782 AVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEEREL 841
A KELE + +V + F A E+ + ++ R++ + +
Sbjct: 271 AAKELE------EVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 324
Query: 842 RAKQEQEKELLRQKLLKEQEEK---------RLREKEEQKKLLEQRAQYVEKTKNILMFT 892
R K+ Q K R +K + R K +++ R+ +K K+
Sbjct: 325 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 384
Query: 893 GETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEG 952
E E KEK R R ++ E + N D D + ++K + K E+E E E+
Sbjct: 385 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 444
Query: 953 GERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKA 1012
+++K+K + D E E + K R EK+K K R PP +S
Sbjct: 445 RDKEKEKEQ----------DKEKE---REKDRSKEIDEKRKKDKKSRTPP------RSYN 485
Query: 1013 IISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGS 1072
S SS E + R S S+S S + K SS S S ++NK
Sbjct: 486 ASRRSRSSSRERR--------RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK------- 530
Query: 1073 PRRPRRQRSDQDSDSDQPSRKR----RPSGSEQSDNESVQSGRSHSGVSENDSRPASPSA 1128
+ +++ ++D S++ R+R R S +++ E ++ + E++ P S +
Sbjct: 531 --KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 588
Query: 1129 ESDHESERGSDNEGSGQGSGN 1149
+ + + E Q +GN
Sbjct: 589 KEVDDKDAPRTEENKIQHNGN 609
Score = 66.6 bits (161), Expect = 1e-10
Identities = 72/321 (22%), Positives = 124/321 (38%), Gaps = 34/321 (10%)
Query: 873 KLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGR---RSKKGGEFDEFVNDDTDDDL 929
K LE+ + V + ++ + E E+ K +R GG R RSK
Sbjct: 273 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 332
Query: 930 PISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKA 989
S+ R + ++ +R K + RR + S D + K K++ K
Sbjct: 333 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 392
Query: 990 ---EKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED 1046
EK++ + ER +GK K + D ++D+ K ++ R + D D
Sbjct: 393 KDREKEREREKEREKEKERGKNKDR------DKEREKDREKDKEKDREREREKEHEKDRD 446
Query: 1047 EQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNES 1106
++++K E D ++ + K S+ +R + ++S S SR+ R S E+ S
Sbjct: 447 KEKEK----EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS 502
Query: 1107 VQSGRS---HSGVSENDSRPASPSA----------ESDHESERGSDNEGSGQGSGNESEP 1153
S RS + SR SP + E DH SER + E S + ++
Sbjct: 503 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSMRKSSNDR 561
Query: 1154 EG----SNNEASDRGSEHGSD 1170
+G N S + EH +
Sbjct: 562 DGKEKLEKNSTSLKEKEHNKE 582
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 68.6 bits (166), Expect = 3e-11
Identities = 83/381 (21%), Positives = 147/381 (38%), Gaps = 55/381 (14%)
Query: 782 AVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEEREL 841
A KELE + +V + F A E+ + ++ R++ + +
Sbjct: 155 AAKELE------EVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHS 208
Query: 842 RAKQEQEKELLRQKLLKEQEEK---------RLREKEEQKKLLEQRAQYVEKTKNILMFT 892
R K+ Q K R +K + R K +++ R+ +K K+
Sbjct: 209 RRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI 268
Query: 893 GETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEG 952
E E KEK R R ++ E + N D D + ++K + K E+E E E+
Sbjct: 269 KEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD 328
Query: 953 GERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKA 1012
+++K+K + D E E + K R EK+K K R PP +S
Sbjct: 329 RDKEKEKEQ----------DKEKE---REKDRSKEIDEKRKKDKKSRTPP------RSYN 369
Query: 1013 IISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGS 1072
S SS E + R S S+S S + K SS S S ++NK
Sbjct: 370 ASRRSRSSSRERR--------RRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK------- 414
Query: 1073 PRRPRRQRSDQDSDSDQPSRKR----RPSGSEQSDNESVQSGRSHSGVSENDSRPASPSA 1128
+ +++ ++D S++ R+R R S +++ E ++ + E++ P S +
Sbjct: 415 --KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 472
Query: 1129 ESDHESERGSDNEGSGQGSGN 1149
+ + + E Q +GN
Sbjct: 473 KEVDDKDAPRTEENKIQHNGN 493
Score = 66.6 bits (161), Expect = 1e-10
Identities = 72/321 (22%), Positives = 124/321 (38%), Gaps = 34/321 (10%)
Query: 873 KLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGR---RSKKGGEFDEFVNDDTDDDL 929
K LE+ + V + ++ + E E+ K +R GG R RSK
Sbjct: 157 KELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSK 216
Query: 930 PISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKA 989
S+ R + ++ +R K + RR + S D + K K++ K
Sbjct: 217 HRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKE 276
Query: 990 ---EKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED 1046
EK++ + ER +GK K + D ++D+ K ++ R + D D
Sbjct: 277 KDREKEREREKEREKEKERGKNKDR------DKEREKDREKDKEKDREREREKEHEKDRD 330
Query: 1047 EQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNES 1106
++++K E D ++ + K S+ +R + ++S S SR+ R S E+ S
Sbjct: 331 KEKEK----EQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRS 386
Query: 1107 VQSGRS---HSGVSENDSRPASPSA----------ESDHESERGSDNEGSGQGSGNESEP 1153
S RS + SR SP + E DH SER + E S + ++
Sbjct: 387 RSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISER-RERERSTSMRKSSNDR 445
Query: 1154 EG----SNNEASDRGSEHGSD 1170
+G N S + EH +
Sbjct: 446 DGKEKLEKNSTSLKEKEHNKE 466
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 68.2 bits (165), Expect = 4e-11
Identities = 100/531 (18%), Positives = 206/531 (38%), Gaps = 53/531 (9%)
Query: 622 REKEKRHQDRALAIY-KQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQVREATADI 680
+EKEK Q + +Y K+ L + K L G F + + AQV E
Sbjct: 1848 QEKEKLAQRKENLLYNKERLTHSKKQLVQVKN------KLGMFNK---ILAQVEEKLTQE 1898
Query: 681 SDVWLNLAHIYVEQKQYISAVQMYENCLRKFYKHQNTEVVLYLARALFKCGK-------- 732
+ + E ++ + VQ+ ++ +K K ++ L L +A+ + K
Sbjct: 1899 KETVIKKKEKLAETEKKL--VQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDI 1956
Query: 733 LQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVKELELAHRY 792
+E K L+ + +A L+ + + + K E ++L L +
Sbjct: 1957 AKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKI 2016
Query: 793 FSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELL 852
+ ++ ++A E + + Q Q +A+A ++ ++RE +K+ + +
Sbjct: 2017 LLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKI 2076
Query: 853 RQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSK 912
+ L K ++R +EE K +RA +V KE++ +
Sbjct: 2077 LKALQKLTRDERKLTQEEIKMTKMKRALFV----------------KERRLSIEQSKLDI 2120
Query: 913 KGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDD 972
K +F E ++ T D+ +++K+++ ++E+ E + K R+H E D
Sbjct: 2121 KEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKH---SEVILD 2177
Query: 973 DETENG-------PKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDK 1025
DE E G P K+R + E K+ KP K K S+ S++ E+
Sbjct: 2178 DEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKP-------KEKFSSQVDEVESEEHFSEEM 2230
Query: 1026 LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDS 1085
+ DE + S S+ + +E E+ ++ E +E + K E + + + +
Sbjct: 2231 ESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKK 2290
Query: 1086 DSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESER 1136
++ + + + E + S +S+ + S S E + + E+
Sbjct: 2291 KKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREK 2341
Score = 57.0 bits (136), Expect = 1e-07
Identities = 64/302 (21%), Positives = 132/302 (43%), Gaps = 32/302 (10%)
Query: 769 LKDEKSNLKEVLNAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHV 828
L E + L ++L A+++L R + KM+ L + L ++
Sbjct: 2066 LSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDF 2125
Query: 829 ARARKQ-DEEERELRAKQEQEKELLRQKLLKEQ----EEKRLREKEEQKKLLEQRAQYVE 883
+ R + ++E++L KQ + +R+ + KE+ EE +L K + L ++ +E
Sbjct: 2126 SEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIE 2185
Query: 884 KTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDD--TDDDLPISKKKKRRKGS 941
+ + I KE KRG + K + DE +++ +++ + + ++++
Sbjct: 2186 EEEVIPFLKRRWRKRKEAKRGDKP--KEKFSSQVDEVESEEHFSEEMESLLDELEKQESL 2243
Query: 942 GSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLP 1001
SE+E E EE ER++++ R EE + E E G + + + + +KKK
Sbjct: 2244 SSEEEEEREEEEEREEEEVR-----EEEEERKEEEEGEEKQVEKEEEEKKKKK------- 2291
Query: 1002 PSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDE 1061
K K K + ++ +E + +++E + S SDE+E+ + C+ E E
Sbjct: 2292 -----KEKKKEEVQEKEEVFEEKEEIMSEE------ETESLSDEEEEEESCSLEEEVDRE 2340
Query: 1062 NQ 1063
+
Sbjct: 2341 KE 2342
Score = 39.7 bits (91), Expect = 0.017
Identities = 62/326 (19%), Positives = 136/326 (41%), Gaps = 49/326 (15%)
Query: 732 KLQECKQTLLKARHVAPSDTVLMFNVALVLQRLATSVLKDEKSNLKEVLNAVK---ELEL 788
KL + + L+K R + + + LQ+L +DE+ +E + K L +
Sbjct: 2051 KLAKASRKLIKKRESLSKEPAKLNKILKALQKLT----RDERKLTQEEIKMTKMKRALFV 2106
Query: 789 AHRYFSYLSKVGDKMRFDLALAATE--------ARQCSDLLSQAQYHVARARKQDEEERE 840
R S D +D + +E AR+ L ++ + + + K EEE +
Sbjct: 2107 KERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESK 2166
Query: 841 LRAKQ------EQEKELLRQKLLKEQEEKRLREKEEQK---KLLEQRAQYVEKTKNILMF 891
L K ++E+ + ++ + ++R R+++E K K E+ + V++ ++ F
Sbjct: 2167 LARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHF 2226
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGS--GSEQEGED 949
+ E E+ ++ + S E +E ++ ++ + ++++ RK G E++ E
Sbjct: 2227 SEEMESLLDELEK----QESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 950 EEGGERKKKKRRRHPKGEEG-------------------SDDDETENGPKPKKRRPPKAE 990
EE ++KKKK ++ + +E SD++E E ++ + E
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Query: 991 KKKAPKPERLPPSMKGKIKSKAIISS 1016
K K +L + ++ + + S
Sbjct: 2343 ILKKEKQFKLQEQRRKSLRGRERVLS 2368
Score = 33.5 bits (75), Expect = 1.2
Identities = 45/239 (18%), Positives = 99/239 (41%), Gaps = 28/239 (11%)
Query: 813 EARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLRE----- 867
E R + A+ H RAR + + +E R ++E++L +++ QEE++L +
Sbjct: 1564 EQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKI 1623
Query: 868 KEEQKKLLEQRAQYVEKTKNILM----FTGETE---------ATKEKKRGGGGGRRSKKG 914
++ +++ + ++ +K + + + E E A K +K + +KKG
Sbjct: 1624 TQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKG 1683
Query: 915 GEFDEFVN--DDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDD 972
G+ E N ++LP ++ + QE E+ E + + EEG
Sbjct: 1684 GKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLV 1743
Query: 973 DETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADE 1031
+E K++ + E+ A + E+L + + ++ + + K K+ +E
Sbjct: 1744 EE--------KKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEE 1794
Score = 31.6 bits (70), Expect = 4.6
Identities = 59/322 (18%), Positives = 131/322 (40%), Gaps = 49/322 (15%)
Query: 783 VKELELAHRYFSYLSKVGDKMRFDLALAATEARQCSDLLSQAQYHVARARKQDE---EER 839
++E E H+ LS + ++ D L E +Q + + ++ + + ++E EE
Sbjct: 1490 LQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYKDEEEVTLEEE 1549
Query: 840 ELRAKQEQEKELLRQKLLKEQEEK-----RLREKEEQKKLLEQRAQYVEKTKNILMFTGE 894
R +E+E+++ ++ ++E K R R + E+K+ E+R E+ K + E
Sbjct: 1550 VSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEK---LAQEE 1606
Query: 895 TEATKEKKRGGGGGRRSKKGGEFDEFVNDDTD---DDLPISKKKKRRKGSGSEQEGEDEE 951
+ +E++ K + + DD + + ++K++ G + E E+
Sbjct: 1607 RQLAQEER---------KLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEK 1657
Query: 952 GGERKKKKRRRHPK--------GEEGSDDDETENGPKPKKRRPPK-------AEKKKAPK 996
+++KK ++ K ++G E +N K P+ EK+ A +
Sbjct: 1658 LAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQE 1717
Query: 997 PERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDED---------- 1046
E L M+ + ++ + E+K K+A+E S+E+
Sbjct: 1718 LEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELL 1777
Query: 1047 -EQRKKCASSESDSDENQNKSG 1067
++++K A + E + + G
Sbjct: 1778 IQEKEKLAQHKEKMPEEEERLG 1799
Score = 31.6 bits (70), Expect = 4.6
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 15/86 (17%)
Query: 832 RKQDEEERELRAKQE-----QEKELLRQ-KLLKEQEEKRLREKEEQ-----KKLLEQRAQ 880
+++ E E + QE QEKE L Q K +EE+RL K EQ KL ++R +
Sbjct: 1759 QREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRER 1818
Query: 881 YV----EKTKNILMFTGETEATKEKK 902
++ E TKN ++ + +EKK
Sbjct: 1819 WINSMEELTKNKMILYQKKNLAQEKK 1844
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform 8
[Homo sapiens]
Length = 780
Score = 67.4 bits (163), Expect = 8e-11
Identities = 83/397 (20%), Positives = 172/397 (43%), Gaps = 61/397 (15%)
Query: 761 LQRLATSVLKDEKSNLKE---VLNAVKELELAHRYFSYLSKVGDKMRFDLALAATEARQC 817
++RL S +D K + E + + E+ + + + + D+ D +LA +Q
Sbjct: 32 IKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQM 91
Query: 818 SDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKK--LL 875
S + +H R ++ +E++ R K E+E+E R+K +E+++K RE E QK+ +
Sbjct: 92 SR--KEKVHH--RKDEKRKEKKHARVK-EKEREHERRKRHREEQDKARREWERQKRREMA 146
Query: 876 EQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKK 935
+ ++ + +F E + K+ R +K E ++K
Sbjct: 147 REHSRRERGNDGVCLFRDRLEQLERKR------ERERKMRE----------------QQK 184
Query: 936 KRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPK--KRRPPKAEKKK 993
++R+ E+ E+ RK+++ RR + ++ + K R PP+ +++
Sbjct: 185 EQREQKERERRAEE----RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 240
Query: 994 APKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKK-- 1051
+ P + K++ + ++S D SD ++ + E S S S+ +E+E+ ++
Sbjct: 241 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 300
Query: 1052 --CASSESDSDENQNK-------SGSEAGSPRRPRRQRSDQDSDSDQ-----------PS 1091
S ES+ +E + + S SE S + ++ S+ ++ S
Sbjct: 301 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 360
Query: 1092 RKRRPSG-SEQSDNESVQSGRSHSGVSENDSRPASPS 1127
R R SG SE+++ E + S ++E D P SP+
Sbjct: 361 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPA 397
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/349 (20%), Positives = 137/349 (39%), Gaps = 31/349 (8%)
Query: 837 EERELRAKQEQEKELLRQKLLKEQEEKR--LREKEEQKKLLE---QRAQYVEKTKNILMF 891
+E++ R +QE++ E+ R K +++ KR L E E + +E + + Y + ++ +
Sbjct: 18 QEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSPY--RREDSMED 75
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEE 951
GE + + K R+ K DE + + +++ R+ E++ +
Sbjct: 76 RGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARR 135
Query: 952 GGERKKKKR--RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIK 1009
ER+K++ R H + E G+D G + R + E+K+ + ++ K + +
Sbjct: 136 EWERQKRREMAREHSRRERGND------GVCLFRDRLEQLERKRE-RERKMREQQKEQRE 188
Query: 1010 SKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSE 1069
K +++ E + + H R ED K AS S S + E
Sbjct: 189 QKERERRAEERRKEREARREVSAHHRTMR------EDYSDKVKASHWSRSPPRPPRERFE 242
Query: 1070 AGSPRRPRRQRSDQDSD-----SDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPA 1124
G R+P ++ ++ D D +R+ S +E S ES E +
Sbjct: 243 LGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEG 302
Query: 1125 SPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
S S ESE + E + + E S A + E S+D +
Sbjct: 303 STS----EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEE 347
Score = 45.8 bits (107), Expect = 2e-04
Identities = 62/337 (18%), Positives = 121/337 (35%), Gaps = 38/337 (11%)
Query: 867 EKEEQK-KLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDT 925
EK+ K K L++ Q ++ K E E E KR R K +E D
Sbjct: 4 EKDSWKVKTLDEILQEKKRRK-------EQEEKAEIKRLKNSDDRDSKRDSLEEGELRDH 56
Query: 926 DDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRR 985
++ I RR+ S ++ ED+ + ++ R K D+ E K +
Sbjct: 57 CMEITIRNSPYRREDSMEDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEK 116
Query: 986 PPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSD--------------------EDK 1025
+ E++K + E+ + + + + ++ + E +
Sbjct: 117 EREHERRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERE 176
Query: 1026 LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQN---------KSGSEAGSPRRP 1076
K+ ++ + + +E+RK+ + S ++ K+ + SP RP
Sbjct: 177 RKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRP 236
Query: 1077 RRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESER 1136
R+R + ++ SD + + + +E+ S + +E + E E
Sbjct: 237 PRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE 296
Query: 1137 GSDNEGS-GQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
+ EGS + S E E E E + SE S+ S
Sbjct: 297 EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS 333
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 66.2 bits (160), Expect = 2e-10
Identities = 55/301 (18%), Positives = 122/301 (40%), Gaps = 20/301 (6%)
Query: 855 KLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKG 914
K+ E++ K + + E++ ++E++ + + T+ + + +E K GG +G
Sbjct: 437 KVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEG 496
Query: 915 GE-------FDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGE 967
GE +E + + + P+ ++ K + S ++ E + E K ++ + P E
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 968 EGSDDDETENGPK-----------PKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISS 1016
E E ++ K P+K + P E+ K+P + P K +K +A +
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616
Query: 1017 SDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEA-GSPRR 1075
S +++ K E + +E + +K S E + ++ K+ S +
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676
Query: 1076 PRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVS-ENDSRPASPSAESDHES 1134
P + +S +++ P + + P E E +S S E P A++ ++
Sbjct: 677 PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKA 736
Query: 1135 E 1135
+
Sbjct: 737 K 737
Score = 53.1 bits (126), Expect = 1e-06
Identities = 62/334 (18%), Positives = 132/334 (39%), Gaps = 24/334 (7%)
Query: 813 EARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQK 872
EA+ S + K +E E+ K ++++ K E+ + KEE K
Sbjct: 687 EAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA-KTPEKAKSPVKEEAK 745
Query: 873 KLLEQRAQYVEKTKNILMFTGETEA-TKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPI 931
++A+ EK K + + + E + KE+ R K E V P+
Sbjct: 746 S--PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPL 803
Query: 932 SKKKKRRKGSGSEQEG------EDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRR 985
+ K + ++E E+E+ E K K+ + + E+ +TE KK
Sbjct: 804 KEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEE 863
Query: 986 PPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDE 1045
PK E K E+ P+++ K K + + +++ D+ K+ ++ P D+
Sbjct: 864 APKKEAPKPKVEEKKEPAVE-KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDA-- 920
Query: 1046 DEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSD-QDSDSDQPSRKRRPSGSEQSDN 1104
+ ++K ++ + D+ + K S+ + ++ D ++ + +P K + + D+
Sbjct: 921 -KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDD 979
Query: 1105 ESV---------QSGRSHSGVSENDSRPASPSAE 1129
+++ + S + DS+P + E
Sbjct: 980 KTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 50.4 bits (119), Expect = 1e-05
Identities = 62/319 (19%), Positives = 125/319 (39%), Gaps = 18/319 (5%)
Query: 829 ARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNI 888
A++ ++E + AK +++E +K E+ + KEE K E ++ EK K+
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP--EKAKSP 607
Query: 889 LMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDL--PISKKKKRRKGSGSEQE 946
+ E ++ E K +S + E T ++ P K ++ + S ++
Sbjct: 608 VK--EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Query: 947 GEDEEGGERKKKKRRRHP-----KGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLP 1001
+ E K ++ + P K E + E P+K + P E+ K+P+ + P
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 1002 PSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDE 1061
+ K KA +++ +K K ++ + S + K+ A S +D
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKS---PEAKTPAKEEARSPADKFP 782
Query: 1062 NQNKS--GSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ--SGRSHSGVS 1117
+ KS E SP + + + ++ K+ S + E Q + +
Sbjct: 783 EKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKA 842
Query: 1118 ENDSRPASPSAESDHESER 1136
E + PA+P E +S++
Sbjct: 843 EEEKAPATPKTEEKKDSKK 861
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 65.9 bits (159), Expect = 2e-10
Identities = 92/399 (23%), Positives = 148/399 (37%), Gaps = 66/399 (16%)
Query: 796 LSKVGDKMRFDLALAATEA-RQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQ 854
LS+V +K F A AT+ S LL + + A+ ER+L+A K+ ++
Sbjct: 27 LSEVANK--FAKATGATQQDANASSLLDIYSFWLKSAKVP---ERKLQANGPVAKKAKKK 81
Query: 855 KLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKG 914
+ E+ E+E Q + A K+ G G+ + K
Sbjct: 82 ASSSDSEDSSEEEEEVQGP------------------PAKKAAVPAKRVGLPPGKAAAKA 123
Query: 915 GEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDE 974
E DDD KK+ +KG + + + KK + + S +DE
Sbjct: 124 SESSSSEESSDDDDEEDQKKQPVQKGVKPQAKA-----AKAPPKKAKSSDSDSDSSSEDE 178
Query: 975 TENGPKPKKRRPP-KAEKKKAPKPERLPPSM-KGKIKSKAIISSSDDSSDED-------- 1024
KPK KA+ K PKP R P + GK S + SSS SSD+
Sbjct: 179 PPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAAT 238
Query: 1025 ------------KLKIADEGHP-RNSNSNSDSDEDEQRKKCASSESDSDENQNKSG--SE 1069
K + P R S+S+ DS DE+ E +NK G S
Sbjct: 239 PKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEE-------EEQKKPMKNKPGPYSS 291
Query: 1070 AGSPRRPRRQRSDQDSDSDQPSRKRRP-----SGSEQSDNESVQSGRSHSGVSENDSRPA 1124
P P ++S + K++P S++SD+ S + + + + +
Sbjct: 292 VPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTK 351
Query: 1125 SPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDR 1163
P A+ ES S + S + S+P G+ +S++
Sbjct: 352 PPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNK 390
Score = 60.1 bits (144), Expect = 1e-08
Identities = 53/238 (22%), Positives = 103/238 (43%), Gaps = 33/238 (13%)
Query: 933 KKKKRRKGSGSEQEGEDEEGGERKKKKR------------------RRHPKGEEGSDDDE 974
+K RK S E E E K KK ++ P+G S D
Sbjct: 414 QKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSSDS 473
Query: 975 TENGPKPKKRRPPKAEKKKAPK-------PERLPPSMKGKIKSKAIISSSDDSSDEDKLK 1027
+ + ++ + K+ KK P+ P + + KGK +S SSSDDSS+E++ K
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNS-SSSDDSSEEEEEK 532
Query: 1028 IADEGHPRNS--NSNSDSDEDEQRKKCASSESDSDENQNKSG---SEAGSPRRPRRQRSD 1082
+ +G PR +N S Q K A + + +E + K+ S++GS ++ ++ +
Sbjct: 533 LKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAA 592
Query: 1083 QDSDSDQPS--RKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGS 1138
+++++ Q + + P+ + ++ V E + S A++ +++RG+
Sbjct: 593 KEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGA 650
Score = 54.7 bits (130), Expect = 5e-07
Identities = 62/337 (18%), Positives = 126/337 (37%), Gaps = 26/337 (7%)
Query: 829 ARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNI 888
A K+ ++++ AK + + E+ E+EEQKK ++ +
Sbjct: 236 AATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPP- 294
Query: 889 LMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGE 948
+ +K G +++ + + E D +D+ S+++K+ +
Sbjct: 295 -----PSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKAT 349
Query: 949 DEEGGERKKKKRRRHPKGEEGSDDDETENGP----KPKKRRPPKAEKKKAPKPERLPPSM 1004
+ +K + + S+DDE + P K +P K A KP P
Sbjct: 350 TKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQP 409
Query: 1005 KGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQN 1064
G K + +D SS E++ +S S+E++ +K A+++ +
Sbjct: 410 VGG-GQKLLTRKADSSSSEEE--------------SSSSEEEKTKKMVATTKPKATAKAA 454
Query: 1065 KSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHS-GVSENDSRP 1123
S +P+ R SD DS S + ++ + + + V G + S S +
Sbjct: 455 LSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKA 514
Query: 1124 ASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEA 1160
S ++ S +S + + G+GS P+ + A
Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSA 551
Score = 33.9 bits (76), Expect = 0.93
Identities = 39/201 (19%), Positives = 79/201 (39%), Gaps = 22/201 (10%)
Query: 892 TGETEATKEKKRGGGGGRRSK----KGGEFDEFVNDDTDDDLPISKKKKRRKGSG----- 942
T ++ K+ ++ GG SK K G+ + + +DD ++K + KGS
Sbjct: 485 TSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAP 544
Query: 943 --------SEQEGEDEEGGERKKKKRRRHPK--GEEGSDDDETENGPKPKKRRPPKAEKK 992
+ Q G+ + E +++++++ + GS +N K+ P+A+K
Sbjct: 545 KANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQN-EAAKEAETPQAKKI 603
Query: 993 KAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDE--DEQRK 1050
K P P KG+ ++ + + E ++AD + D E ++ K
Sbjct: 604 KLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLK 663
Query: 1051 KCASSESDSDENQNKSGSEAG 1071
++ + K GS G
Sbjct: 664 FTKGKSFRHEKTKKKRGSYRG 684
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 65.9 bits (159), Expect = 2e-10
Identities = 77/349 (22%), Positives = 142/349 (40%), Gaps = 60/349 (17%)
Query: 834 QDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTG 893
+++E L A + +EL RQK + E+R + +++
Sbjct: 70 ENDEPLNLNASDSESEELHRQKDSDSESEERAEPPASD-----------SENEDVNQHGS 118
Query: 894 ETEATKEKKRGGGGGRRSK-KGGEFDEFVNDDT-DDDLPISKKKKRRKGSGSEQEGEDEE 951
++E+ + +K G + G + N+D S+ ++ +K S+ E ED
Sbjct: 119 DSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDAL 178
Query: 952 GGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSK 1011
+ + P+ + + D E E PKP R +E ++ PKP+
Sbjct: 179 KPQISDSESEEPPRHQ--ASDSENEEPPKP---RMSDSESEELPKPQ------------- 220
Query: 1012 AIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAG 1071
SD S+E PR+ S+S E+E+ K S+S+S++ S++
Sbjct: 221 ----VSDSESEEP---------PRHQASDS---ENEELPKPRISDSESEDPPRHQASDSE 264
Query: 1072 SPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSR-PASPSAES 1130
+ P+ + S DS+S+ P R + + S+NE + R SE + PAS S
Sbjct: 265 NEELPKPRIS--DSESEDPPRNQ----ASDSENEELPKPRVSDSESEGPQKGPASDSETE 318
Query: 1131 D---HESERGSDNEGSGQGSGNESEPEGS---NNEASDRGSEHGSDDSD 1173
D H+ + SD++ + G ++E + ++ DR H SD +
Sbjct: 319 DASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEE 367
Score = 65.1 bits (157), Expect = 4e-10
Identities = 85/380 (22%), Positives = 148/380 (38%), Gaps = 54/380 (14%)
Query: 834 QDEEERELRAKQEQEKELLRQKLLKEQEE---KRLREKEEQKKLLEQRAQYVEKTKNILM 890
+ EE R+L + +ELL + E K E ++L + A E +
Sbjct: 121 ESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQKSPASDSETEDALKP 180
Query: 891 FTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDE 950
++E+ + + + ++D ++LP + + D
Sbjct: 181 QISDSESEEPPRHQASDSENEEPP---KPRMSDSESEELPKPQVSDSESEEPPRHQASDS 237
Query: 951 EGGERKKKK----RRRHPKGEEGSDDDETENGPKPK-----KRRPPK-----AEKKKAPK 996
E E K + P + SD E E PKP+ PP+ +E ++ PK
Sbjct: 238 ENEELPKPRISDSESEDPPRHQASDS-ENEELPKPRISDSESEDPPRNQASDSENEELPK 296
Query: 997 PERLPPSMKGKIKSKAIISSSDDSS----------DEDKLKIADEGHPRNSNSNSDS--- 1043
P +G K A S ++D+S D D+ ++ +N + +SDS
Sbjct: 297 PRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMD 356
Query: 1044 -------DEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRR- 1095
D +E+ K +SD DE K G E +R SD + + ++K R
Sbjct: 357 RKKFHSSDSEEEEHKKQKMDSDEDE---KEGEEEKVAKRKAAVLSDSEDEEKASAKKSRV 413
Query: 1096 PSGSEQSDNESV--QSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEP 1153
S ++ SD+++V +SG+ ++ +DS + SD ++E D GS SGNE E
Sbjct: 414 VSDADDSDSDAVSDKSGKREKTIA-SDSEEEAGKELSDKKNEE-KDLFGSDSESGNEEE- 470
Query: 1154 EGSNNEASDRGSEHGSDDSD 1173
N +D E G ++ +
Sbjct: 471 ----NLIADIFGESGDEEEE 486
Score = 53.1 bits (126), Expect = 1e-06
Identities = 61/277 (22%), Positives = 109/277 (39%), Gaps = 37/277 (13%)
Query: 919 EFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENG 978
E+ + D DD G + + E + G + + +H + GS + +EN
Sbjct: 4 EYYSGDQSDD-----------GGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSENE 52
Query: 979 PKPKKRRPPKAE---KKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPR 1035
++ PK + +P L S + + SD S+E A +
Sbjct: 53 TSDREDGLPKGHHVTDSENDEPLNLNAS-DSESEELHRQKDSDSESEERAEPPASDSENE 111
Query: 1036 NSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRR 1095
+ N + E E+ +K S+S+++E N S++ + + SD + + Q K
Sbjct: 112 DVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIEELQ---KSP 168
Query: 1096 PSGSEQ--------SDNESVQSGRSHSGVSENDSRPASPSAESDHE-------SERGSDN 1140
S SE SD+ES + R + SEN+ P ++S+ E S+ S+
Sbjct: 169 ASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEELPKPQVSDSESEE 228
Query: 1141 EGSGQGSGNESE----PEGSNNEASDRGSEHGSDDSD 1173
Q S +E+E P S++E+ D SD +
Sbjct: 229 PPRHQASDSENEELPKPRISDSESEDPPRHQASDSEN 265
Score = 35.4 bits (80), Expect = 0.32
Identities = 66/301 (21%), Positives = 109/301 (36%), Gaps = 61/301 (20%)
Query: 834 QDEEERELRAKQEQEKELLRQKLLKEQEEKRLR------EKEEQKK--LLEQRAQYVEKT 885
+ E+ +A + +EL + ++ + E R E EE K + + ++ +K
Sbjct: 251 ESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKG 310
Query: 886 KNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQ 945
T + K+K R KG E E ND D + +KK S E+
Sbjct: 311 PASDSETEDASRHKQKPESDDDSDRENKG-EDTEMQNDSFHSDSHMDRKKFHSSDSEEEE 369
Query: 946 E-------GEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKK------ 992
EDE+ GE +K +R K SD ++ E K R A+
Sbjct: 370 HKKQKMDSDEDEKEGEEEKVAKR---KAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVS 426
Query: 993 -KAPKPERLPPS----------MKGKIKSKAIISSSDDSSDEDKLKIAD----------- 1030
K+ K E+ S K + K + S +S +E++ IAD
Sbjct: 427 DKSGKREKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEE 486
Query: 1031 -------------EGHPRNSNS-NSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRP 1076
+G + + +SDSD++ +R K SD + + S +G RR
Sbjct: 487 EFTGFNQEDLEEEKGETQVKEAEDSDSDDNIKRGKHMDFLSDFEMMLQRKKSMSGKRRRN 546
Query: 1077 R 1077
R
Sbjct: 547 R 547
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 65.9 bits (159), Expect = 2e-10
Identities = 62/240 (25%), Positives = 91/240 (37%), Gaps = 32/240 (13%)
Query: 897 ATKEKKRGGGGGRRSKKGGEFDEFVNDDTD-DDLPISKKKKRRKGSG----------SEQ 945
A E++ G GGG ++ E+ E D + D+ KKK R K G E
Sbjct: 94 AKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKES 153
Query: 946 EGEDEEGGERKKKKRRRHPKGEEGSD---------DDETENGPKPKKRRPPKAEKKKAPK 996
EGE+E+ E K + + E+ +D ++E N K +R K+ +
Sbjct: 154 EGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRS 213
Query: 997 PERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSE 1056
R + +S++ SS S + + R S S S S S
Sbjct: 214 SSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS---------RSHR 264
Query: 1057 SDSDENQNKSGSEAGSPRRPR-RQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSG 1115
S + S + SP R R R RS S D+ R+ R E+ S SG SHSG
Sbjct: 265 GSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTRSRSPERRHRSS--SGSSHSG 322
Score = 56.2 bits (134), Expect = 2e-07
Identities = 50/168 (29%), Positives = 65/168 (38%), Gaps = 6/168 (3%)
Query: 1005 KGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASS----ESDSD 1060
K K + KA+ +S EDK +E S DEDE S ++ +
Sbjct: 131 KKKYRGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEE 190
Query: 1061 ENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEND 1120
E+ NK S S + R S S S PS R S S + S QS RS S S
Sbjct: 191 EDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRSRSRSSSSSQS-RSRSS-SRER 248
Query: 1121 SRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHG 1168
SR + S S RGS + S + S PE + + R S G
Sbjct: 249 SRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSG 296
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 65.5 bits (158), Expect = 3e-10
Identities = 87/418 (20%), Positives = 152/418 (36%), Gaps = 83/418 (19%)
Query: 801 DKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKE- 859
+K R L ++ RQ +Y + ++R R + + + L ++ KE
Sbjct: 1052 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI 1111
Query: 860 ---QEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGE 916
E E K +QR K K +++ KEKKR +K +
Sbjct: 1112 QSGSSSSDAEESSEDNKKKKQRTS--SKKKAVIV--------KEKKRNSLRTSTKRKQAD 1161
Query: 917 FDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRR---HPKGEEGS--- 970
+ D +DD + G GS E + + E G+E
Sbjct: 1162 ITSSSSSDIEDD------DQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKS 1215
Query: 971 -----DDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDK 1025
DDD+ +N P+ + + E+ KA +SS +D S +D+
Sbjct: 1216 VPVTVDDDDDDNDPENRIAKKMLLEEIKAN------------------LSSDEDGSSDDE 1257
Query: 1026 LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDS 1085
+EG R N ++ DE+ K +SESDSD ++K R + SD +S
Sbjct: 1258 ---PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGES 1314
Query: 1086 DSDQPSR-----------KRRPSGSEQSDNESVQSGRSHS-GVSENDSRPASPSAESDH- 1132
++ ++ +R+ S + D++ +SG S SE++ RP + SA+
Sbjct: 1315 GEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1374
Query: 1133 ------------------ESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
+ + S+N+ + + E E E E + E +DDS
Sbjct: 1375 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1432
Score = 59.3 bits (142), Expect = 2e-08
Identities = 62/349 (17%), Positives = 132/349 (37%), Gaps = 33/349 (9%)
Query: 815 RQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKL 874
R ++ S + A +D ++++ R +++ ++++K ++ R K +Q +
Sbjct: 1106 RNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEK---KRNSLRTSTKRKQADI 1162
Query: 875 LEQRAQYVEKTKNILMFTGETEATKEKK--------------RGGGGGRRSKKGGEFDEF 920
+ +E + G ++ K K + G SK +
Sbjct: 1163 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1222
Query: 921 VNDDTDDDLPISKK---KKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETEN 977
+DD D + I+KK ++ + S+++G ++ E ++ K+R + EE D+E +N
Sbjct: 1223 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD--EPEEGKKRTGKQNEENPGDEEAKN 1280
Query: 978 GPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNS 1037
+ + KK P + ++ + S +S +E K K + +
Sbjct: 1281 QVNSESDSDSEESKK---------PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR 1331
Query: 1038 NSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPS 1097
N S ED + ES E ++S E R ++ +++ +K+R
Sbjct: 1332 NRRKVSSEDSEDSDF--QESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1389
Query: 1098 GSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQG 1146
Q D+ S S E + E + E + D++ G+G
Sbjct: 1390 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1438
Score = 54.3 bits (129), Expect = 7e-07
Identities = 52/234 (22%), Positives = 94/234 (40%), Gaps = 23/234 (9%)
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKK-RRKGSGSEQEGEDE 950
+ + E + KKR G + E VN ++D D SKK + R + + D
Sbjct: 1253 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG 1312
Query: 951 EGGERKKKKRRRHPK----------GEEGSDDDETENGPKPK------KRRPPKAEKKKA 994
E GE KK K + H + E+ D D E+G + ++RP KKA
Sbjct: 1313 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1372
Query: 995 PKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCAS 1054
E S K K K + I +DSS E+K +E + + +E+E+ +
Sbjct: 1373 ELEEN-QRSYKQK-KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE---- 1426
Query: 1055 SESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
E+D ++ K + + + R++ + + +R+ + + E ++
Sbjct: 1427 DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLR 1480
Score = 53.1 bits (126), Expect = 1e-06
Identities = 55/269 (20%), Positives = 114/269 (42%), Gaps = 28/269 (10%)
Query: 835 DEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGE 894
+ EE + R ++ E+ ++ + + + EE KK + K +GE
Sbjct: 1257 EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGE 1316
Query: 895 TEATKEKKRGGGGGRRSKK----GGEFDEFVNDDTDDDLPISKKKKR-RKGSGSEQEGED 949
+ TK K+ GR +K E +F +++ S+ ++R R S + E E+
Sbjct: 1317 EKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE 1376
Query: 950 EEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIK 1009
+ ++KKKRRR E+ S ++++ + + +++ + E+++ + E
Sbjct: 1377 NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE---------- 1426
Query: 1010 SKAIISSSDDSSDEDK-----LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQN 1064
+DDS K KI + R N+ +E+E+RK+ A E + ++ +
Sbjct: 1427 -----DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1481
Query: 1065 KSGSEAGSPRR---PRRQRSDQDSDSDQP 1090
E SP + + D+D ++ +P
Sbjct: 1482 VIEIEDASPTKCPITTKLVLDEDEETKEP 1510
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/244 (21%), Positives = 100/244 (40%), Gaps = 62/244 (25%)
Query: 970 SDDDETENGPKPKKRRPPKAEKKKA---------PKPERLPPSMKGKIKSKAIISSSDDS 1020
SD++ E + +K P +K K PKP +LP KSK + +S
Sbjct: 639 SDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLP-------KSKQSETVDQNS 691
Query: 1021 SDEDKLKIADEGHPRNSNSNSDSDEDE----------------------QRKKCASSESD 1058
++ L I E + +S+SD+D +E +++K ++S SD
Sbjct: 692 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD 751
Query: 1059 SDENQNKSGSEAGSPRRPRRQRSDQ---DSDSDQPSRKRRPSGSEQSDNESVQSGRSHSG 1115
D + KS + ++ R+ +S+ DS+ ++ + G+ ++ + + + +
Sbjct: 752 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD- 810
Query: 1116 VSENDSRPASPSAESDHESERGSDNEG------SGQGSGNESEPEGSNNEASDRGSEHGS 1169
S+E + S++G DN+G S +GS +++E E S G+
Sbjct: 811 -----------SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAE---RKQERETFSSAEGT 856
Query: 1170 DDSD 1173
D D
Sbjct: 857 VDKD 860
Score = 45.1 bits (105), Expect = 4e-04
Identities = 54/236 (22%), Positives = 89/236 (37%), Gaps = 36/236 (15%)
Query: 830 RARKQDEEERELRAKQEQEKELLRQKLL----KEQEEKRLREKE--EQKKLLEQRAQYVE 883
+ + + + E K LLR KL + EEK+ + KE E K ++ +
Sbjct: 1281 QVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSED 1340
Query: 884 KTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRK---- 939
+ +G +E E + RS K E +E + +KKKRR+
Sbjct: 1341 SEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE-------NQRSYKQKKKRRRIKVQ 1393
Query: 940 -GSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKK--KAPK 996
S SE + EE E K+++ EE +++E E + P K KK K K
Sbjct: 1394 EDSSSENKSNSEEEEEEKEEEE------EEEEEEEEEEEDENDDSKSPGKGRKKIRKILK 1447
Query: 997 PERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKC 1052
++L + +K + +E + +IA+ R ED KC
Sbjct: 1448 DDKLRTETQNALKEE----------EERRKRIAEREREREKLREVIEIEDASPTKC 1493
Score = 37.7 bits (86), Expect = 0.065
Identities = 56/338 (16%), Positives = 131/338 (38%), Gaps = 28/338 (8%)
Query: 835 DEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGE 894
D E E +K+ + + + ++ E++++++ V+K I+
Sbjct: 810 DSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL--R 867
Query: 895 TEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGE 954
K+++ K G+ F + + +K K K ++ ++G
Sbjct: 868 DRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKV---QDGLS 924
Query: 955 RKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPK-----------PERLPPS 1003
+K + + +E S+DD+ ++ ++++ P KKK K E+LP
Sbjct: 925 DIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPER 984
Query: 1004 MKGKIKSKAIISSSDDSSDEDK--LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDE 1061
+ K I + ++D +K KI D+ + + SD E+ S S++
Sbjct: 985 EEICHFPKGIKQIKNGTTDGEKKSKKIRDK---TSKKKDELSDYAEKSTGKGDSCDSSED 1041
Query: 1062 NQNKSGSEAGSPRR-------PRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHS 1114
++K+G+ +R R+++ SD+++ S K S + ++ +
Sbjct: 1042 KKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRN 1101
Query: 1115 GVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESE 1152
S+ +++ + S E DN+ Q + ++ +
Sbjct: 1102 LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKK 1139
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 65.5 bits (158), Expect = 3e-10
Identities = 87/418 (20%), Positives = 152/418 (36%), Gaps = 83/418 (19%)
Query: 801 DKMRFDLALAATEARQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKE- 859
+K R L ++ RQ +Y + ++R R + + + L ++ KE
Sbjct: 1090 EKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEI 1149
Query: 860 ---QEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGETEATKEKKRGGGGGRRSKKGGE 916
E E K +QR K K +++ KEKKR +K +
Sbjct: 1150 QSGSSSSDAEESSEDNKKKKQRTS--SKKKAVIV--------KEKKRNSLRTSTKRKQAD 1199
Query: 917 FDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRR---HPKGEEGS--- 970
+ D +DD + G GS E + + E G+E
Sbjct: 1200 ITSSSSSDIEDD------DQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKS 1253
Query: 971 -----DDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDK 1025
DDD+ +N P+ + + E+ KA +SS +D S +D+
Sbjct: 1254 VPVTVDDDDDDNDPENRIAKKMLLEEIKAN------------------LSSDEDGSSDDE 1295
Query: 1026 LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDS 1085
+EG R N ++ DE+ K +SESDSD ++K R + SD +S
Sbjct: 1296 ---PEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGES 1352
Query: 1086 DSDQPSR-----------KRRPSGSEQSDNESVQSGRSHS-GVSENDSRPASPSAESDH- 1132
++ ++ +R+ S + D++ +SG S SE++ RP + SA+
Sbjct: 1353 GEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL 1412
Query: 1133 ------------------ESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
+ + S+N+ + + E E E E + E +DDS
Sbjct: 1413 EENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDS 1470
Score = 59.3 bits (142), Expect = 2e-08
Identities = 62/349 (17%), Positives = 132/349 (37%), Gaps = 33/349 (9%)
Query: 815 RQCSDLLSQAQYHVARARKQDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKL 874
R ++ S + A +D ++++ R +++ ++++K ++ R K +Q +
Sbjct: 1144 RNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEK---KRNSLRTSTKRKQADI 1200
Query: 875 LEQRAQYVEKTKNILMFTGETEATKEKK--------------RGGGGGRRSKKGGEFDEF 920
+ +E + G ++ K K + G SK +
Sbjct: 1201 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1260
Query: 921 VNDDTDDDLPISKK---KKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETEN 977
+DD D + I+KK ++ + S+++G ++ E ++ K+R + EE D+E +N
Sbjct: 1261 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDD--EPEEGKKRTGKQNEENPGDEEAKN 1318
Query: 978 GPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNS 1037
+ + KK P + ++ + S +S +E K K + +
Sbjct: 1319 QVNSESDSDSEESKK---------PRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR 1369
Query: 1038 NSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPS 1097
N S ED + ES E ++S E R ++ +++ +K+R
Sbjct: 1370 NRRKVSSEDSEDSDF--QESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1427
Query: 1098 GSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQG 1146
Q D+ S S E + E + E + D++ G+G
Sbjct: 1428 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG 1476
Score = 54.3 bits (129), Expect = 7e-07
Identities = 52/234 (22%), Positives = 94/234 (40%), Gaps = 23/234 (9%)
Query: 892 TGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKK-RRKGSGSEQEGEDE 950
+ + E + KKR G + E VN ++D D SKK + R + + D
Sbjct: 1291 SSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDG 1350
Query: 951 EGGERKKKKRRRHPK----------GEEGSDDDETENGPKPK------KRRPPKAEKKKA 994
E GE KK K + H + E+ D D E+G + ++RP KKA
Sbjct: 1351 ESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKA 1410
Query: 995 PKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCAS 1054
E S K K K + I +DSS E+K +E + + +E+E+ +
Sbjct: 1411 ELEEN-QRSYKQK-KKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE---- 1464
Query: 1055 SESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQ 1108
E+D ++ K + + + R++ + + +R+ + + E ++
Sbjct: 1465 DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLR 1518
Score = 53.1 bits (126), Expect = 1e-06
Identities = 55/269 (20%), Positives = 114/269 (42%), Gaps = 28/269 (10%)
Query: 835 DEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGE 894
+ EE + R ++ E+ ++ + + + EE KK + K +GE
Sbjct: 1295 EPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGE 1354
Query: 895 TEATKEKKRGGGGGRRSKK----GGEFDEFVNDDTDDDLPISKKKKR-RKGSGSEQEGED 949
+ TK K+ GR +K E +F +++ S+ ++R R S + E E+
Sbjct: 1355 EKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE 1414
Query: 950 EEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIK 1009
+ ++KKKRRR E+ S ++++ + + +++ + E+++ + E
Sbjct: 1415 NQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEE---------- 1464
Query: 1010 SKAIISSSDDSSDEDK-----LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQN 1064
+DDS K KI + R N+ +E+E+RK+ A E + ++ +
Sbjct: 1465 -----DENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLRE 1519
Query: 1065 KSGSEAGSPRR---PRRQRSDQDSDSDQP 1090
E SP + + D+D ++ +P
Sbjct: 1520 VIEIEDASPTKCPITTKLVLDEDEETKEP 1548
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/244 (21%), Positives = 100/244 (40%), Gaps = 62/244 (25%)
Query: 970 SDDDETENGPKPKKRRPPKAEKKKA---------PKPERLPPSMKGKIKSKAIISSSDDS 1020
SD++ E + +K P +K K PKP +LP KSK + +S
Sbjct: 677 SDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLP-------KSKQSETVDQNS 729
Query: 1021 SDEDKLKIADEGHPRNSNSNSDSDEDE----------------------QRKKCASSESD 1058
++ L I E + +S+SD+D +E +++K ++S SD
Sbjct: 730 DSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSD 789
Query: 1059 SDENQNKSGSEAGSPRRPRRQRSDQ---DSDSDQPSRKRRPSGSEQSDNESVQSGRSHSG 1115
D + KS + ++ R+ +S+ DS+ ++ + G+ ++ + + + +
Sbjct: 790 FDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD- 848
Query: 1116 VSENDSRPASPSAESDHESERGSDNEG------SGQGSGNESEPEGSNNEASDRGSEHGS 1169
S+E + S++G DN+G S +GS +++E E S G+
Sbjct: 849 -----------SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAE---RKQERETFSSAEGT 894
Query: 1170 DDSD 1173
D D
Sbjct: 895 VDKD 898
Score = 45.1 bits (105), Expect = 4e-04
Identities = 54/236 (22%), Positives = 89/236 (37%), Gaps = 36/236 (15%)
Query: 830 RARKQDEEERELRAKQEQEKELLRQKLL----KEQEEKRLREKE--EQKKLLEQRAQYVE 883
+ + + + E K LLR KL + EEK+ + KE E K ++ +
Sbjct: 1319 QVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSED 1378
Query: 884 KTKNILMFTGETEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRK---- 939
+ +G +E E + RS K E +E + +KKKRR+
Sbjct: 1379 SEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEE-------NQRSYKQKKKRRRIKVQ 1431
Query: 940 -GSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKK--KAPK 996
S SE + EE E K+++ EE +++E E + P K KK K K
Sbjct: 1432 EDSSSENKSNSEEEEEEKEEEE------EEEEEEEEEEEDENDDSKSPGKGRKKIRKILK 1485
Query: 997 PERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKC 1052
++L + +K + +E + +IA+ R ED KC
Sbjct: 1486 DDKLRTETQNALKEE----------EERRKRIAEREREREKLREVIEIEDASPTKC 1531
Score = 37.7 bits (86), Expect = 0.065
Identities = 56/338 (16%), Positives = 131/338 (38%), Gaps = 28/338 (8%)
Query: 835 DEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTGE 894
D E E +K+ + + + ++ E++++++ V+K I+
Sbjct: 848 DSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL--R 905
Query: 895 TEATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGE 954
K+++ K G+ F + + +K K K ++ ++G
Sbjct: 906 DRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKV---QDGLS 962
Query: 955 RKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPK-----------PERLPPS 1003
+K + + +E S+DD+ ++ ++++ P KKK K E+LP
Sbjct: 963 DIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPER 1022
Query: 1004 MKGKIKSKAIISSSDDSSDEDK--LKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDE 1061
+ K I + ++D +K KI D+ + + SD E+ S S++
Sbjct: 1023 EEICHFPKGIKQIKNGTTDGEKKSKKIRDK---TSKKKDELSDYAEKSTGKGDSCDSSED 1079
Query: 1062 NQNKSGSEAGSPRR-------PRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHS 1114
++K+G+ +R R+++ SD+++ S K S + ++ +
Sbjct: 1080 KKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRN 1139
Query: 1115 GVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESE 1152
S+ +++ + S E DN+ Q + ++ +
Sbjct: 1140 LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKK 1177
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 65.5 bits (158), Expect = 3e-10
Identities = 66/355 (18%), Positives = 138/355 (38%), Gaps = 68/355 (19%)
Query: 847 QEKELLRQKLLKEQEEKRLREKEEQKK------LLEQRAQYVEKTKNILMFTGETEATKE 900
+E + L ++L + +E+ E+E+ K + E+ ++ V K N+ + +++
Sbjct: 4769 EEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQ 4828
Query: 901 KKRGGGGGRRSKKGGEFDEFVNDDTD----------------------------DDLPIS 932
K+ + GG+ ++ +N+ D DDL +
Sbjct: 4829 DKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLD 4888
Query: 933 KKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKK 992
+ K +EGE+E E K+K + EE + + +N E +
Sbjct: 4889 SEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQN------------ESQ 4936
Query: 993 KAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKC 1052
+PE P S D + E+++ + ++ + + +EQ++
Sbjct: 4937 SPQEPEEGP-------------SEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSV 4983
Query: 1053 ASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRS 1112
+ ++DE ++G A +P+ + +DSD+++ + P E+ ++ S
Sbjct: 4984 EEKDKEADEEGGENGP-ADQGFQPQEEEEREDSDTEE----QVPEALERKEHASC----G 5034
Query: 1113 HSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEH 1167
+GV + A A + E E+G + GSG N++E SN A +H
Sbjct: 5035 QTGVENMQNTQAMELAGAAPEKEQGKEEHGSGAADANQAEGHESNFIAQLASQKH 5089
Score = 51.6 bits (122), Expect = 4e-06
Identities = 59/262 (22%), Positives = 95/262 (36%), Gaps = 32/262 (12%)
Query: 916 EFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPKGEEGSDDDET 975
+FD ++D ++ +K +G ++ D G E K R +E D++E
Sbjct: 4732 DFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEE 4791
Query: 976 ENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPR 1035
+N + + + + K + L K KS+ D +E + AD+G
Sbjct: 4792 DNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQ------QDKKEEKEEAEADDGGQG 4845
Query: 1036 NSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQDSDSDQPSRKRR 1095
N DE D DEN+ + P + D D + S +
Sbjct: 4846 EDKINEQIDE-----------RDYDENE-VDPYHGNQEKVPEPEALDLPDDLNLDSEDK- 4892
Query: 1096 PSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEP-E 1154
+G E +DNE G EN E+ HE+E + E S + EP E
Sbjct: 4893 -NGGEDTDNEE--------GEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEE 4943
Query: 1155 GSNNEASDRGSEH---GSDDSD 1173
G + + G E G+DD D
Sbjct: 4944 GPSEDDKAEGEEEMDTGADDQD 4965
Score = 42.7 bits (99), Expect = 0.002
Identities = 35/168 (20%), Positives = 66/168 (39%), Gaps = 2/168 (1%)
Query: 1005 KGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESDSDENQN 1064
KG+ K K S D ED E + +++E +K S D D++
Sbjct: 4705 KGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMG 4764
Query: 1065 K-SGSEAGSPRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRP 1123
+G EA D++ D ++ K +G + +S + + S N ++
Sbjct: 4765 DLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKD 4824
Query: 1124 ASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDD 1171
S + + + E +D+ G G+ NE E +E ++ HG+ +
Sbjct: 4825 KSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDE-NEVDPYHGNQE 4871
Score = 35.8 bits (81), Expect = 0.25
Identities = 57/283 (20%), Positives = 106/283 (37%), Gaps = 53/283 (18%)
Query: 834 QDEEERELRAKQEQEKELLRQKLLKEQEEKRLREKEEQKKLLEQRAQYVEKTKNILMFTG 893
Q+EEERE +EQ E L E++E + + ++ T+ + +
Sbjct: 5007 QEEEEREDSDTEEQVPEAL--------------ERKEHASCGQTGVENMQNTQAMELAGA 5052
Query: 894 ETEATKEKKRGGGGGRRSKKG-GEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEG 952
E + K+ G G + + G F+ ++ +K RK + S + +
Sbjct: 5053 APEKEQGKEEHGSGAADANQAEGHESNFI-------AQLASQKHTRKNTQSFKRKPGQAD 5105
Query: 953 GERK--KKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKS 1010
ER R H + D E GP + P+A+ + A E + K S
Sbjct: 5106 NERSMGDHNERVHKRLRTVDTDSHAEQGP----AQQPQAQVEDADAFEHI------KQGS 5155
Query: 1011 KAIISSS-DDSSDEDKLKIADEGHPRNSNSNSDS--DEDEQRKKCASSESDSDENQNKSG 1067
A + + D +S E + D G + D+ D +EQ + A+ + KSG
Sbjct: 5156 DAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSG 5215
Query: 1068 SEA----------------GSPRRPRRQRSDQDSDSDQPSRKR 1094
+ A + PR ++ +++++++P R R
Sbjct: 5216 TTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSR 5258
Score = 34.3 bits (77), Expect = 0.72
Identities = 53/266 (19%), Positives = 92/266 (34%), Gaps = 46/266 (17%)
Query: 940 GSGSEQEGEDEEGG--ERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPP-KAEKKKAPK 996
G G+ + + E GG E + K G E +D + G + K P K++ K
Sbjct: 4666 GEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDN 4725
Query: 997 PERLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSE 1056
+ GK+ + +D D + H + N DE+ E
Sbjct: 4726 AIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEE 4785
Query: 1057 SDSDENQNKSGSEAGSPRRPRRQRSDQ---------DSDSDQPSRKRRPSGSEQSDNESV 1107
D +E NK+ E G P D DS + + ++ E+ + E+
Sbjct: 4786 EDEEEEDNKT-EETG----PGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEAD 4840
Query: 1108 QSGRSHSGVS---------ENDSRPASPSAESDHESER---------GSDNEGSGQGSGN 1149
G+ ++ EN+ P + E E E S+++ G+ + N
Sbjct: 4841 DGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDN 4900
Query: 1150 E-----------SEPEGSNNEASDRG 1164
E +PE + +EA +RG
Sbjct: 4901 EEGEEENPLEIKEKPEEAGHEAEERG 4926
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precursor
[Homo sapiens]
Length = 513
Score = 65.1 bits (157), Expect = 4e-10
Identities = 65/280 (23%), Positives = 117/280 (41%), Gaps = 25/280 (8%)
Query: 905 GGGGRRSKKGGEFDEFVNDDTDDDL----PISKKKKRRKGSGSEQEGEDEEGGERKKKKR 960
GG R + KGG+ + DD+ DD K R+ G+ + G DE+ + +
Sbjct: 89 GGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASE 148
Query: 961 RRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSD-D 1019
P+G++ + D +E+ R E + KPE + + + + + SD +
Sbjct: 149 ESAPQGQDSAQDTTSES-------RELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGE 201
Query: 1020 SSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCA---SSESDSDENQNKSGSEAGSP--R 1074
SS D ++ DEG + + S+ R A S ES + Q + GS
Sbjct: 202 SSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLE 261
Query: 1075 RPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSEN--DSRPASPSAESDH 1132
P R+ + S++ R SE DN +++ +S S + N D+ + P +S
Sbjct: 262 HPSRKIFRKSRISEEDDR------SELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKG 315
Query: 1133 ESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDS 1172
+S+ S S + S N P +++ ++ S+ S +S
Sbjct: 316 DSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSES 355
Score = 58.9 bits (141), Expect = 3e-08
Identities = 60/281 (21%), Positives = 104/281 (37%), Gaps = 13/281 (4%)
Query: 903 RGGGGGRRSKKGGEFDEFVNDDTDDDLPISKKKKR---RKGSGSEQEGEDEEGGERKKKK 959
R G +SK+ GE E N + + R RK SE++ E ++
Sbjct: 231 RMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEE 290
Query: 960 RRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPERLPPSMKGKIKSKAIISSSDD 1019
+ S D + K + K+ + E S+ SS +
Sbjct: 291 VKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQE 350
Query: 1020 SSDEDKLKIADEGHPRNSNSNS-------DSDEDEQRKKCASSESDSDENQNKSGSEAGS 1072
+S E + ++ E N + + DSD E+ S S S+ + ++ SE+
Sbjct: 351 NSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSE 410
Query: 1073 PRRPRRQRSDQDSDSDQPSRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDH 1132
+ + D + S++ S S +++ QS SHS ++DS+ +S S E +
Sbjct: 411 SLNFSEESPESPEDENSSSQEGLQSHSSSAES---QSEESHSEEDDSDSQDSSRSKEDSN 467
Query: 1133 ESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSDDSD 1173
+E S +E GQ E E +A DD+D
Sbjct: 468 STESKSSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDND 508
Score = 57.4 bits (137), Expect = 8e-08
Identities = 63/303 (20%), Positives = 108/303 (35%), Gaps = 46/303 (15%)
Query: 896 EATKEKKRGGGGGRRSKKGGEFDEFVNDDTDDDLPISKK-------------KKRRKGSG 942
E+ E+ GGG G+ E ++ D P S + K + G
Sbjct: 186 ESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGEN 245
Query: 943 SEQEGEDEEGG----ERKKKKRRRHPKGEEGSDDDETENGPKPKKRRPPKAEKKKAPKPE 998
SEQ + GG E +K R + E D E ++ ++ + E +
Sbjct: 246 SEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTG 305
Query: 999 RLPPSMKGKIKSKAIISSSDDSSDEDKLKIADEGHPRNSNSNSDSDEDEQRKKCASSESD 1058
P K DS ++ K ++ E + N + S E Q +S E+
Sbjct: 306 LSQPRRDSK----------GDSQEDSKENLSQE---ESQNVDGPSSESSQEANLSSQENS 352
Query: 1059 SDENQNKSGSEAGSPRRPR----RQRSDQDSDSDQP----SRKRRPSGSEQSDNESVQSG 1110
S+ + G P + D DS + S + S EQ+D+ES +S
Sbjct: 353 SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSES- 411
Query: 1111 RSHSGVSENDSRPASPSAESDHESERGSDNEGSGQGSGNESEPEGSNNEASDRGSEHGSD 1170
++ ++ P SP E+ E + S + ES E ++++ D S +
Sbjct: 412 -----LNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQD--SSRSKE 464
Query: 1171 DSD 1173
DS+
Sbjct: 465 DSN 467
Score = 50.4 bits (119), Expect = 1e-05
Identities = 59/291 (20%), Positives = 107/291 (36%), Gaps = 34/291 (11%)
Query: 906 GGGRRSKKGGEFDEFVNDDTDDDLPISKKKKRRKGSGSEQEGEDEEGGERKKKKRRRHPK 965
G G + ++ G +D+ DD + ++ +G S Q+ E + + P+
Sbjct: 120 GPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPE 179
Query: 966 GEEGSDDDETE-----NGPKPKKRRPPKA----EKKKAPKPERLPPSMKGKIKSKAIISS 1016
G + + + E+E G + + E ++ PE + + A + S
Sbjct: 180 GGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKS 239
Query: 1017 SDDSSDEDKLKIADEG------HP-----RNSNSNSDSDEDE--QRKKCASSESDSDENQ 1063
+ + ++ D G HP R S + + D E +SDS EN
Sbjct: 240 KESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENS 299
Query: 1064 NKSGSEAGSPRRPRRQRSDQDS----------DSDQPSRKRRPSGSEQSDNESVQSGRSH 1113
N + PRR + S +DS + D PS + + S S +S
Sbjct: 300 NSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEV 359
Query: 1114 SGVSENDSRPASPSAESDHESERGSDNEGSG--QGSGNESEPEGSNNEASD 1162
S D+ + S D E S+ + S S +ES E +++E+S+
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSE 410
Score = 32.3 bits (72), Expect = 2.7
Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 20/155 (12%)
Query: 1035 RNSNSNSDSDEDEQRKKCASSESDSDENQNKSGSEAGSPRRPRRQRSDQD-------SDS 1087
R N+ S+ E+ + + + +++ GS+ S + SD SD
Sbjct: 21 RYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDPSDSTQSEEGLGSDD 80
Query: 1088 DQP--------SRKRRPSGSEQSDNESVQSGRSHSGVSENDSRPASPSAESDHESERGSD 1139
Q SR G ++ D+E SG G ++DS P + S GSD
Sbjct: 81 HQYIYRLAGGFSRSTGKGGDDKDDDED-DSGDDTFG--DDDSGPGPKDRQEGGNSRLGSD 137
Query: 1140 NEGSGQ-GSGNESEPEGSNNEASDRGSEHGSDDSD 1173
+ + ES P+G ++ A D SE D++
Sbjct: 138 EDSDDTIQASEESAPQGQDS-AQDTTSESRELDNE 171
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,507,741
Number of Sequences: 37866
Number of extensions: 2320975
Number of successful extensions: 41276
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 624
Number of HSP's successfully gapped in prelim test: 1485
Number of HSP's that attempted gapping in prelim test: 16051
Number of HSP's gapped (non-prelim): 12888
length of query: 1173
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1060
effective length of database: 13,968,660
effective search space: 14806779600
effective search space used: 14806779600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.