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Search of human proteins with 7657309
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
(365 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens] 773 0.0
gi|7661666 testin isoform 1 [Homo sapiens] 386 e-107
gi|23238188 testin isoform 2 [Homo sapiens] 378 e-105
gi|7710129 LIM domain only 6 [Homo sapiens] 196 4e-50
gi|38524620 prickle-like 2 [Homo sapiens] 179 3e-45
gi|222136684 prickle homolog 1 [Homo sapiens] 173 2e-43
gi|222136682 prickle homolog 1 [Homo sapiens] 173 2e-43
gi|222136680 prickle homolog 1 [Homo sapiens] 173 2e-43
gi|222136678 prickle homolog 1 [Homo sapiens] 173 2e-43
gi|118722347 over-expressed breast tumor protein [Homo sapiens] 133 2e-31
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens] 73 5e-13
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 73 5e-13
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens] 73 5e-13
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 73 5e-13
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 73 5e-13
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens] 73 5e-13
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens] 73 5e-13
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 72 6e-13
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 72 6e-13
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 72 6e-13
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 72 6e-13
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 72 6e-13
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 71 2e-12
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 71 2e-12
gi|109638745 transforming growth factor beta 1 induced transcrip... 69 7e-12
gi|21361591 transforming growth factor beta 1 induced transcript... 69 7e-12
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 69 9e-12
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 69 9e-12
gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo ... 68 1e-11
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ... 68 1e-11
>gi|7657309 LIM and cysteine-rich domains 1 [Homo sapiens]
Length = 365
Score = 773 bits (1997), Expect = 0.0
Identities = 365/365 (100%), Positives = 365/365 (100%)
Query: 1 MAKVAKDLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLT 60
MAKVAKDLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLT
Sbjct: 1 MAKVAKDLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLT 60
Query: 61 SDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEW 120
SDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEW
Sbjct: 61 SDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEW 120
Query: 121 APPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELK 180
APPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELK
Sbjct: 121 APPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELK 180
Query: 181 LMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVE 240
LMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVE
Sbjct: 181 LMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVE 240
Query: 241 YVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHY 300
YVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHY
Sbjct: 241 YVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHY 300
Query: 301 CESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
CESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS
Sbjct: 301 CESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
Query: 361 KSKRS 365
KSKRS
Sbjct: 361 KSKRS 365
>gi|7661666 testin isoform 1 [Homo sapiens]
Length = 421
Score = 386 bits (991), Expect = e-107
Identities = 182/356 (51%), Positives = 243/356 (68%), Gaps = 8/356 (2%)
Query: 7 DLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDD 66
DL VKKM LG Q G CL CK C GFE H WRKIC++CKC QE+H + E+D
Sbjct: 2 DLENKVKKMGLGHEQGF-GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEED 60
Query: 67 RKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVT 126
RK+G+L D+KY+TL A++K DGI +YKRN MI+TNP+A K+ + +T+TYEWAPP
Sbjct: 61 RKVGKLFEDTKYTTLIAKLKS-DGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQN 119
Query: 127 QKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFV 186
Q L QYM+++PKEKQPV G+EGA YR++QL QLP +DQDPS+C L E+K ME+FV
Sbjct: 120 QALARQYMQMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFV 179
Query: 187 KQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPS---KEVEYVC 243
K+YKSEALGVG+V LP + + + KQ P G +T A G++ D S K +Y C
Sbjct: 180 KKYKSEALGVGDVKLPCE--MDAQGPKQMNIPGGDRSTPAAV-GAMEDKSAEHKRTQYSC 236
Query: 244 ELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCES 303
CK + P +Y++RAGY+K WHP CFVC+ C E LVD+IYFWK+ +CGRHYC+S
Sbjct: 237 YCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDS 296
Query: 304 LRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
+PRC+GCDE+IF+ +Y + E+ WH KHF C C+ +L+G Y++ + +C C
Sbjct: 297 EKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPC 352
>gi|23238188 testin isoform 2 [Homo sapiens]
Length = 412
Score = 378 bits (971), Expect = e-105
Identities = 177/348 (50%), Positives = 238/348 (68%), Gaps = 8/348 (2%)
Query: 15 MSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLM 74
M LG Q G CL CK C GFE H WRKIC++CKC QE+H + E+DRK+G+L
Sbjct: 1 MGLGHEQGF-GAPCLKCKEKCEGFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFE 59
Query: 75 DSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYM 134
D+KY+TL A++K DGI +YKRN MI+TNP+A K+ + +T+TYEWAPP Q L QYM
Sbjct: 60 DTKYTTLIAKLKS-DGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYM 118
Query: 135 ELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEAL 194
+++PKEKQPV G+EGA YR++QL QLP +DQDPS+C L E+K ME+FVK+YKSEAL
Sbjct: 119 QMLPKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVKKYKSEAL 178
Query: 195 GVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPS---KEVEYVCELCKGAAP 251
GVG+V LP + + + KQ P G +T A G++ D S K +Y C CK +
Sbjct: 179 GVGDVKLPCE--MDAQGPKQMNIPGGDRSTPAAV-GAMEDKSAEHKRTQYSCYCCKLSMK 235
Query: 252 PDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGC 311
P +Y++RAGY+K WHP CFVC+ C E LVD+IYFWK+ +CGRHYC+S +PRC+GC
Sbjct: 236 EGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIYFWKNEKLYCGRHYCDSEKPRCAGC 295
Query: 312 DEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
DE+IF+ +Y + E+ WH KHF C C+ +L+G Y++ + +C C
Sbjct: 296 DELIFSNEYTQAENQNWHLKHFCCFDCDSILAGEIYVMVNDKPVCKPC 343
>gi|7710129 LIM domain only 6 [Homo sapiens]
Length = 615
Score = 196 bits (497), Expect = 4e-50
Identities = 111/343 (32%), Positives = 157/343 (45%), Gaps = 58/343 (16%)
Query: 24 RGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLED-DRKIGRLLMDSKYSTLT 82
RG C C+ C GF H WRKIC+ CKC +E+H + + D +R + RL+ D + +++
Sbjct: 23 RGQPCNSCREQCPGFLLHGWRKICQHCKCPREEHAVHAVPVDLERIMCRLISDFQRHSIS 82
Query: 83 ARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQ 142
D + Y W PPG+ + Q+ +P++K
Sbjct: 83 -------------------------DDDSGCASEEYAWVPPGLKPEQVYQFFSCLPEDKV 117
Query: 143 PVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALP 202
P + G YR +QL+HQLP +D + C L E E K + F +Q K E LG G V +
Sbjct: 118 PYVNSPGEKYRIKQLLHQLPPHDSEAQYCTALEEEEKKELRAFSQQRKRENLGRGIVRI- 176
Query: 203 GQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRA 262
T G+ +CE C V++ RA
Sbjct: 177 ---------------------FPVTITGA----------ICEECGKQIGGGDIAVFASRA 205
Query: 263 GYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQR 322
G WHP CFVC C E LVDLIYF+ G +CGRH+ E LRPRC CDEIIF+ +
Sbjct: 206 GLGACWHPQCFVCTTCQELLVDLIYFYHVGKVYCGRHHAECLRPRCQACDEIIFSPECTE 265
Query: 323 VEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
E WH HF C CE L G+ Y++ + + C C +++ +
Sbjct: 266 AEGRHWHMDHFCCFECEASLGGQRYVMRQSRPHCCACYEARHA 308
>gi|38524620 prickle-like 2 [Homo sapiens]
Length = 844
Score = 179 bits (454), Expect = 3e-45
Identities = 94/245 (38%), Positives = 126/245 (51%), Gaps = 32/245 (13%)
Query: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177
Y W PPG+ + QY +P+EK P + G R +QL+HQLP +D + C L E
Sbjct: 37 YAWVPPGLKPEQVHQYYSCLPEEKVPYVNSPGEKLRIKQLLHQLPPHDNEVRYCNSLDEE 96
Query: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237
E + ++ F Q K E LG G V +P T A
Sbjct: 97 EKRELKLFSSQRKRENLGRGNV-----------------RPFPVTMTGA----------- 128
Query: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297
+CE C G V++ RAG+ WHP CFVC C+E LVDLIYF++DG +CG
Sbjct: 129 ----ICEQCGGQINGGDIAVFASRAGHGVCWHPPCFVCTVCNELLVDLIYFYQDGKIYCG 184
Query: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
RH+ E L+PRC+ CDEIIFA++ E WH KHF C CE +L G+ YI+ +G+ C
Sbjct: 185 RHHAECLKPRCAACDEIIFADECTEAEGRHWHMKHFCCFECETVLGGQRYIMKEGRPYCC 244
Query: 358 TCSKS 362
C +S
Sbjct: 245 HCFES 249
Score = 30.0 bits (66), Expect = 3.4
Identities = 13/35 (37%), Positives = 18/35 (51%), Gaps = 2/35 (5%)
Query: 266 KQWHPT--CFVCAKCSEPLVDLIYFWKDGAPWCGR 298
+ WH T CF CA C + L+ + K G +C R
Sbjct: 274 QHWHATETCFCCAHCKKSLLGRPFLPKQGQIFCSR 308
>gi|222136684 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 173 bits (439), Expect = 2e-43
Identities = 92/245 (37%), Positives = 124/245 (50%), Gaps = 32/245 (13%)
Query: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177
Y W PPG+ + Y +P+EK P + G +R +QL++QLP +D + C+ L E
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237
E K ++ F Q K EALG G + L + +
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLLSRAVM------------------------------ 122
Query: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297
VCE C V++ RAG WHP+CFVC C+E LVDLIYF++DG CG
Sbjct: 123 --HAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
RH+ E L+PRCS CDEIIFA++ E WH KHF C CE +L G+ YI+ G+ C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 358 TCSKS 362
C +S
Sbjct: 241 GCFES 245
Score = 29.6 bits (65), Expect = 4.4
Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 6/58 (10%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPT--CFVCAKCSEPLVDLIYFWKDGAPWCGR 298
CE C D + D + WH T CF CA+C L+ + K G +C +
Sbjct: 251 CETCGEHIGVDHAQMTYD----GQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
>gi|222136682 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 173 bits (439), Expect = 2e-43
Identities = 92/245 (37%), Positives = 124/245 (50%), Gaps = 32/245 (13%)
Query: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177
Y W PPG+ + Y +P+EK P + G +R +QL++QLP +D + C+ L E
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237
E K ++ F Q K EALG G + L + +
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLLSRAVM------------------------------ 122
Query: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297
VCE C V++ RAG WHP+CFVC C+E LVDLIYF++DG CG
Sbjct: 123 --HAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
RH+ E L+PRCS CDEIIFA++ E WH KHF C CE +L G+ YI+ G+ C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 358 TCSKS 362
C +S
Sbjct: 241 GCFES 245
Score = 29.6 bits (65), Expect = 4.4
Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 6/58 (10%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPT--CFVCAKCSEPLVDLIYFWKDGAPWCGR 298
CE C D + D + WH T CF CA+C L+ + K G +C +
Sbjct: 251 CETCGEHIGVDHAQMTYD----GQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
>gi|222136680 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 173 bits (439), Expect = 2e-43
Identities = 92/245 (37%), Positives = 124/245 (50%), Gaps = 32/245 (13%)
Query: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177
Y W PPG+ + Y +P+EK P + G +R +QL++QLP +D + C+ L E
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237
E K ++ F Q K EALG G + L + +
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLLSRAVM------------------------------ 122
Query: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297
VCE C V++ RAG WHP+CFVC C+E LVDLIYF++DG CG
Sbjct: 123 --HAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
RH+ E L+PRCS CDEIIFA++ E WH KHF C CE +L G+ YI+ G+ C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 358 TCSKS 362
C +S
Sbjct: 241 GCFES 245
Score = 29.6 bits (65), Expect = 4.4
Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 6/58 (10%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPT--CFVCAKCSEPLVDLIYFWKDGAPWCGR 298
CE C D + D + WH T CF CA+C L+ + K G +C +
Sbjct: 251 CETCGEHIGVDHAQMTYD----GQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
>gi|222136678 prickle homolog 1 [Homo sapiens]
Length = 831
Score = 173 bits (439), Expect = 2e-43
Identities = 92/245 (37%), Positives = 124/245 (50%), Gaps = 32/245 (13%)
Query: 118 YEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLEN 177
Y W PPG+ + Y +P+EK P + G +R +QL++QLP +D + C+ L E
Sbjct: 33 YAWVPPGLRPEQIQLYFACLPEEKVPYVNSPGEKHRIKQLLYQLPPHDNEVRYCQSLSEE 92
Query: 178 ELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSK 237
E K ++ F Q K EALG G + L + +
Sbjct: 93 EKKELQVFSAQRKKEALGRGTIKLLSRAVM------------------------------ 122
Query: 238 EVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCG 297
VCE C V++ RAG WHP+CFVC C+E LVDLIYF++DG CG
Sbjct: 123 --HAVCEQCGLKINGGEVAVFASRAGPGVCWHPSCFVCFTCNELLVDLIYFYQDGKIHCG 180
Query: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
RH+ E L+PRCS CDEIIFA++ E WH KHF C CE +L G+ YI+ G+ C
Sbjct: 181 RHHAELLKPRCSACDEIIFADECTEAEGRHWHMKHFCCLECETVLGGQRYIMKDGRPFCC 240
Query: 358 TCSKS 362
C +S
Sbjct: 241 GCFES 245
Score = 29.6 bits (65), Expect = 4.4
Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 6/58 (10%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPT--CFVCAKCSEPLVDLIYFWKDGAPWCGR 298
CE C D + D + WH T CF CA+C L+ + K G +C +
Sbjct: 251 CETCGEHIGVDHAQMTYD----GQHWHATEACFSCAQCKASLLGCPFLPKQGQIYCSK 304
>gi|118722347 over-expressed breast tumor protein [Homo sapiens]
Length = 384
Score = 133 bits (335), Expect = 2e-31
Identities = 73/209 (34%), Positives = 97/209 (46%), Gaps = 32/209 (15%)
Query: 157 LMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQE 216
L+ QLP D D C L E E ++ F + K EALG G L LPK EG
Sbjct: 70 LLQQLPPQDIDERYCLALGEEERAELQLFCARRKQEALGQGVARLV----LPKLEG---- 121
Query: 217 KPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCA 276
+ CE C+ P V++ RAG + WH CF C
Sbjct: 122 ------------------------HTCEKCRELLKPGEYGVFAARAGEQRCWHQPCFACQ 157
Query: 277 KCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCE 336
C + L++LIYF+ DG +CGRH+ E LRPRC CD++IF+ E WH HF C+
Sbjct: 158 ACGQALINLIYFYHDGQLYCGRHHAELLRPRCPACDQLIFSWRCTEAEGQRWHENHFCCQ 217
Query: 337 GCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
C L G Y + G CP+C +++ S
Sbjct: 218 DCAGPLGGGRYALPGGSPCCPSCFENRYS 246
>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
Length = 194
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C C+ DS V+ N+ WH TCF CAKC PL + + KD C +
Sbjct: 40 CVECRKPIGADSKEVHYK----NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 303 SLRPRCSGCDEIIFAEDYQRVE--DLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
P+C GC + I A D Q VE WH+ F C C+Q++ ++ C TC
Sbjct: 96 EDSPKCKGCFKAIVAGD-QNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 154
Query: 361 KSK 363
++K
Sbjct: 155 ETK 157
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C +PL Y KDG C + + + C C + I A+ + ++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L+ ++ ++LC C+ + S
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
Score = 28.5 bits (62), Expect = 9.9
Identities = 24/99 (24%), Positives = 36/99 (36%), Gaps = 8/99 (8%)
Query: 218 PEGAETTAATTNGSLSDP--SKEVEYVCELC-KGAAPPDSPVVYSDRAGYNKQWHPTCFV 274
P ET A N L + ++E C+ C K D V Y WH CF
Sbjct: 74 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTV-----WHKDCFT 128
Query: 275 CAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDE 313
C+ C + + +F K +C + C C++
Sbjct: 129 CSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNK 167
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C C+ DS V+ N+ WH TCF CAKC PL + + KD C +
Sbjct: 40 CVECRKPIGADSKEVHYK----NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 303 SLRPRCSGCDEIIFAEDYQRVE--DLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
P+C GC + I A D Q VE WH+ F C C+Q++ ++ C TC
Sbjct: 96 EDSPKCKGCFKAIVAGD-QNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 154
Query: 361 KSK 363
++K
Sbjct: 155 ETK 157
Score = 55.5 bits (132), Expect = 8e-08
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEII--FAEDYQR 322
++ WH CFVC CS+ L + + +C Y + +C+GC I F +
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 323 V--EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
V E +WH F C+ C L+ + ++ + Q+ CP C+K
Sbjct: 238 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 218 PEGAETTAATTNGSLSDP--SKEVEYVCELC-KGAAPPDSPVVYSDRAGYNKQWHPTCFV 274
P ET A N L + ++E C+ C K D V Y WH CF
Sbjct: 74 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTV-----WHKDCFT 128
Query: 275 CAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFV 334
C+ C + + +F K +C + C C++ I + +D WH FV
Sbjct: 129 CSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGIT-YQDQPWHADCFV 187
Query: 335 CEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
C C + L+G+ + + Q C C K+
Sbjct: 188 CVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C +PL Y KDG C + + + C C + I A+ + ++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L+ ++ ++LC C+ + S
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
Length = 323
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C C+ DS V+ N+ WH TCF CAKC PL + + KD C +
Sbjct: 40 CVECRKPIGADSKEVHYK----NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 303 SLRPRCSGCDEIIFAEDYQRVE--DLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
P+C GC + I A D Q VE WH+ F C C+Q++ ++ C TC
Sbjct: 96 EDSPKCKGCFKAIVAGD-QNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 154
Query: 361 KSK 363
++K
Sbjct: 155 ETK 157
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 218 PEGAETTAATTNGSLSDP--SKEVEYVCELC-KGAAPPDSPVVYSDRAGYNKQWHPTCFV 274
P ET A N L + ++E C+ C K D V Y WH CF
Sbjct: 74 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTV-----WHKDCFT 128
Query: 275 CAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFV 334
C+ C + + +F K +C + C C++ I + +D WH FV
Sbjct: 129 CSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGIT-YQDQPWHADCFV 187
Query: 335 CEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
C C + L+G+ + + Q C C K+
Sbjct: 188 CVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C +PL Y KDG C + + + C C + I A+ + ++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L+ ++ ++LC C+ + S
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
Score = 35.8 bits (81), Expect = 0.062
Identities = 22/75 (29%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGC-DEIIFAEDYQRV 323
++ WH CFVC CS+ L + + +C Y + +C+GC + I RV
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGKRTVSRV 237
Query: 324 -EDLAWHRKHFVCEG 337
++ RK VC G
Sbjct: 238 SHPVSKARKPPVCHG 252
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C C+ DS V+ N+ WH TCF CAKC PL + + KD C +
Sbjct: 40 CVECRKPIGADSKEVHYK----NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 303 SLRPRCSGCDEIIFAEDYQRVE--DLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
P+C GC + I A D Q VE WH+ F C C+Q++ ++ C TC
Sbjct: 96 EDSPKCKGCFKAIVAGD-QNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 154
Query: 361 KSK 363
++K
Sbjct: 155 ETK 157
Score = 55.5 bits (132), Expect = 8e-08
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEII--FAEDYQR 322
++ WH CFVC CS+ L + + +C Y + +C+GC I F +
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 323 V--EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
V E +WH F C+ C L+ + ++ + Q+ CP C+K
Sbjct: 238 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 218 PEGAETTAATTNGSLSDP--SKEVEYVCELC-KGAAPPDSPVVYSDRAGYNKQWHPTCFV 274
P ET A N L + ++E C+ C K D V Y WH CF
Sbjct: 74 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTV-----WHKDCFT 128
Query: 275 CAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFV 334
C+ C + + +F K +C + C C++ I + +D WH FV
Sbjct: 129 CSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGIT-YQDQPWHADCFV 187
Query: 335 CEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
C C + L+G+ + + Q C C K+
Sbjct: 188 CVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C +PL Y KDG C + + + C C + I A+ + ++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L+ ++ ++LC C+ + S
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C C+ DS V+ N+ WH TCF CAKC PL + + KD C +
Sbjct: 69 CVECRKPIGADSKEVHYK----NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 124
Query: 303 SLRPRCSGCDEIIFAEDYQRVE--DLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
P+C GC + I A D Q VE WH+ F C C+Q++ ++ C TC
Sbjct: 125 EDSPKCKGCFKAIVAGD-QNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 183
Query: 361 KSK 363
++K
Sbjct: 184 ETK 186
Score = 55.5 bits (132), Expect = 8e-08
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEII--FAEDYQR 322
++ WH CFVC CS+ L + + +C Y + +C+GC I F +
Sbjct: 207 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 266
Query: 323 V--EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
V E +WH F C+ C L+ + ++ + Q+ CP C+K
Sbjct: 267 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 307
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 218 PEGAETTAATTNGSLSDP--SKEVEYVCELC-KGAAPPDSPVVYSDRAGYNKQWHPTCFV 274
P ET A N L + ++E C+ C K D V Y WH CF
Sbjct: 103 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTV-----WHKDCFT 157
Query: 275 CAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFV 334
C+ C + + +F K +C + C C++ I + +D WH FV
Sbjct: 158 CSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGIT-YQDQPWHADCFV 216
Query: 335 CEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
C C + L+G+ + + Q C C K+
Sbjct: 217 CVTCSKKLAGQRFTAVEDQYYCVDCYKN 244
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C +PL Y KDG C + + + C C + I A+ + ++ WH
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L+ ++ ++LC C+ + S
Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 127
>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
Length = 296
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C C+ DS V+ N+ WH TCF CAKC PL + + KD C +
Sbjct: 56 CVECRKPIGADSKEVHYK----NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 111
Query: 303 SLRPRCSGCDEIIFAEDYQRVE--DLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
P+C GC + I A D Q VE WH+ F C C+Q++ ++ C TC
Sbjct: 112 EDSPKCKGCFKAIVAGD-QNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 170
Query: 361 KSK 363
++K
Sbjct: 171 ETK 173
Score = 55.5 bits (132), Expect = 8e-08
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEII--FAEDYQR 322
++ WH CFVC CS+ L + + +C Y + +C+GC I F +
Sbjct: 194 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 253
Query: 323 V--EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
V E +WH F C+ C L+ + ++ + Q+ CP C+K
Sbjct: 254 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 294
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 218 PEGAETTAATTNGSLSDP--SKEVEYVCELC-KGAAPPDSPVVYSDRAGYNKQWHPTCFV 274
P ET A N L + ++E C+ C K D V Y WH CF
Sbjct: 90 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTV-----WHKDCFT 144
Query: 275 CAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFV 334
C+ C + + +F K +C + C C++ I + +D WH FV
Sbjct: 145 CSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGIT-YQDQPWHADCFV 203
Query: 335 CEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
C C + L+G+ + + Q C C K+
Sbjct: 204 CVTCSKKLAGQRFTAVEDQYYCVDCYKN 231
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C +PL Y KDG C + + + C C + I A+ + ++ WH
Sbjct: 21 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 80
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L+ ++ ++LC C+ + S
Sbjct: 81 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 114
>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 72.8 bits (177), Expect = 5e-13
Identities = 40/123 (32%), Positives = 56/123 (45%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C C+ DS V+ N+ WH TCF CAKC PL + + KD C +
Sbjct: 40 CVECRKPIGADSKEVHYK----NRFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTR 95
Query: 303 SLRPRCSGCDEIIFAEDYQRVE--DLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
P+C GC + I A D Q VE WH+ F C C+Q++ ++ C TC
Sbjct: 96 EDSPKCKGCFKAIVAGD-QNVEYKGTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCH 154
Query: 361 KSK 363
++K
Sbjct: 155 ETK 157
Score = 55.5 bits (132), Expect = 8e-08
Identities = 29/101 (28%), Positives = 48/101 (47%), Gaps = 4/101 (3%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEII--FAEDYQR 322
++ WH CFVC CS+ L + + +C Y + +C+GC I F +
Sbjct: 178 DQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSV 237
Query: 323 V--EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
V E +WH F C+ C L+ + ++ + Q+ CP C+K
Sbjct: 238 VAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAK 278
Score = 52.0 bits (123), Expect = 8e-07
Identities = 38/148 (25%), Positives = 58/148 (39%), Gaps = 9/148 (6%)
Query: 218 PEGAETTAATTNGSLSDP--SKEVEYVCELC-KGAAPPDSPVVYSDRAGYNKQWHPTCFV 274
P ET A N L + ++E C+ C K D V Y WH CF
Sbjct: 74 PLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTV-----WHKDCFT 128
Query: 275 CAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFV 334
C+ C + + +F K +C + C C++ I + +D WH FV
Sbjct: 129 CSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGIT-YQDQPWHADCFV 187
Query: 335 CEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
C C + L+G+ + + Q C C K+
Sbjct: 188 CVTCSKKLAGQRFTAVEDQYYCVDCYKN 215
Score = 40.8 bits (94), Expect = 0.002
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C +PL Y KDG C + + + C C + I A+ + ++ WH
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L+ ++ ++LC C+ + S
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNKCTTREDS 98
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 72.4 bits (176), Expect = 6e-13
Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 28/215 (13%)
Query: 169 SRCRGLL--------ENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQE---- 216
S+CR L E++L + + +Y S+ + +PG + + E
Sbjct: 69 SQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFI 128
Query: 217 -----KPEGAETTAATTNGSLSDPSKEVEYV--CELCKGAAPPDSPVVYSDRAGYNKQWH 269
+P G ++ N + P E ++ C CK P+ + WH
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCK------KPITTGGVTYREQPWH 182
Query: 270 PTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF---AEDYQRVEDL 326
CFVC C + L + +D +C +C+ +C+GC I Y E+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEER 242
Query: 327 AWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
WH F C+ C L GR ++ + +LCP C K
Sbjct: 243 QWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 55.8 bits (133), Expect = 6e-08
Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF-AEDYQRV 323
++ WH CF C++C LVD + K+ C Y +C C + I
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 324 EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
+ +WH F+C C+Q + +++I Q C C + + +
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C+E L Y ++ +P+C + C C + I + +D WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L + + + QLLC C ++ S
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 72.4 bits (176), Expect = 6e-13
Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 28/215 (13%)
Query: 169 SRCRGLL--------ENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQE---- 216
S+CR L E++L + + +Y S+ + +PG + + E
Sbjct: 69 SQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFI 128
Query: 217 -----KPEGAETTAATTNGSLSDPSKEVEYV--CELCKGAAPPDSPVVYSDRAGYNKQWH 269
+P G ++ N + P E ++ C CK P+ + WH
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCK------KPITTGGVTYREQPWH 182
Query: 270 PTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF---AEDYQRVEDL 326
CFVC C + L + +D +C +C+ +C+GC I Y E+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEER 242
Query: 327 AWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
WH F C+ C L GR ++ + +LCP C K
Sbjct: 243 QWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 55.8 bits (133), Expect = 6e-08
Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF-AEDYQRV 323
++ WH CF C++C LVD + K+ C Y +C C + I
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 324 EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
+ +WH F+C C+Q + +++I Q C C + + +
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C+E L Y ++ +P+C + C C + I + +D WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L + + + QLLC C ++ S
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 72.4 bits (176), Expect = 6e-13
Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 28/215 (13%)
Query: 169 SRCRGLL--------ENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQE---- 216
S+CR L E++L + + +Y S+ + +PG + + E
Sbjct: 69 SQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFI 128
Query: 217 -----KPEGAETTAATTNGSLSDPSKEVEYV--CELCKGAAPPDSPVVYSDRAGYNKQWH 269
+P G ++ N + P E ++ C CK P+ + WH
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCK------KPITTGGVTYREQPWH 182
Query: 270 PTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF---AEDYQRVEDL 326
CFVC C + L + +D +C +C+ +C+GC I Y E+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEER 242
Query: 327 AWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
WH F C+ C L GR ++ + +LCP C K
Sbjct: 243 QWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 55.8 bits (133), Expect = 6e-08
Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF-AEDYQRV 323
++ WH CF C++C LVD + K+ C Y +C C + I
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 324 EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
+ +WH F+C C+Q + +++I Q C C + + +
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C+E L Y ++ +P+C + C C + I + +D WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L + + + QLLC C ++ S
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 72.4 bits (176), Expect = 6e-13
Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 28/215 (13%)
Query: 169 SRCRGLL--------ENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQE---- 216
S+CR L E++L + + +Y S+ + +PG + + E
Sbjct: 69 SQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFI 128
Query: 217 -----KPEGAETTAATTNGSLSDPSKEVEYV--CELCKGAAPPDSPVVYSDRAGYNKQWH 269
+P G ++ N + P E ++ C CK P+ + WH
Sbjct: 129 CHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCK------KPITTGGVTYREQPWH 182
Query: 270 PTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF---AEDYQRVEDL 326
CFVC C + L + +D +C +C+ +C+GC I Y E+
Sbjct: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEER 242
Query: 327 AWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSK 361
WH F C+ C L GR ++ + +LCP C K
Sbjct: 243 QWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
Score = 55.8 bits (133), Expect = 6e-08
Identities = 25/102 (24%), Positives = 44/102 (43%), Gaps = 1/102 (0%)
Query: 265 NKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF-AEDYQRV 323
++ WH CF C++C LVD + K+ C Y +C C + I
Sbjct: 58 DRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEY 117
Query: 324 EDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
+ +WH F+C C+Q + +++I Q C C + + +
Sbjct: 118 KGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 41.2 bits (95), Expect = 0.001
Identities = 24/94 (25%), Positives = 38/94 (40%), Gaps = 1/94 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRK 331
F C C+E L Y ++ +P+C + C C + I + +D WH
Sbjct: 5 FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS 365
F C C L + + + QLLC C ++ S
Sbjct: 65 CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYS 98
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 72.4 bits (176), Expect = 6e-13
Identities = 55/212 (25%), Positives = 81/212 (38%), Gaps = 27/212 (12%)
Query: 167 DPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQ----------- 215
+P C+ ++EL + + + S+ GE +PG L E G Q
Sbjct: 78 EPFTCQ---DSELLCNDCYCSAFSSQCSACGETVMPGSRKL--EYGGQTWHEHCFLCSGC 132
Query: 216 EKPEGAETTAATTNGSLSDPSKEVEYV--CELCKGAAPPDSPVVYSDRAGYNKQWHPTCF 273
E+P G+ + P E ++ C C V Y D+ WH C
Sbjct: 133 EQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGG-VTYRDQP-----WHRECL 186
Query: 274 VCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIF---AEDYQRVEDLAWHR 330
VC C PL + +D P+C + E P+CS C I Y ED WH
Sbjct: 187 VCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHH 246
Query: 331 KHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
F C C L G+ ++ Q+LC CS++
Sbjct: 247 NCFSCARCSTSLVGQGFVPDGDQVLCQGCSQA 278
Score = 68.2 bits (165), Expect = 1e-11
Identities = 37/123 (30%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 243 CELCKGAAPPDS-PVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYC 301
C C+ DS + Y DR +H CF C +C L D + +D C YC
Sbjct: 40 CAECQQLIGHDSRELFYEDR-----HFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYC 94
Query: 302 ESLRPRCSGCDEIIFAEDYQ-RVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCS 360
+ +CS C E + + WH F+C GCEQ L R+++ KG C C
Sbjct: 95 SAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCY 154
Query: 361 KSK 363
++K
Sbjct: 155 ENK 157
Score = 48.5 bits (114), Expect = 9e-06
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 1/88 (1%)
Query: 273 FVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQR-VEDLAWHRK 331
F CAKC+E L Y D P+C Y + C+ C ++I + + ED +H
Sbjct: 5 FDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEG 64
Query: 332 HFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
F C C++ L+ + +LLC C
Sbjct: 65 CFRCCRCQRSLADEPFTCQDSELLCNDC 92
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 70.9 bits (172), Expect = 2e-12
Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDL- 326
WH TCFVCA C +P + ++ +DG P+C + Y +C GCD + A D + +E L
Sbjct: 519 WHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGD-KFIEALG 577
Query: 327 -AWHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
WH F+C C L G+ + K + LC
Sbjct: 578 HTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
Score = 53.9 bits (128), Expect = 2e-07
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 266 KQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVED 325
+ WHP F CA C L D+ + + +C R Y + P C+ C+ I E +
Sbjct: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQ 517
Query: 326 LAWHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
WH FVC C++ + + G+ C
Sbjct: 518 -TWHTTCFVCAACKKPFGNSLFHMEDGEPYC 547
Score = 36.6 bits (83), Expect = 0.036
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 2/68 (2%)
Query: 234 DPSKEVEYVCELCKGAAPPDSPVVYSDR--AGYNKQWHPTCFVCAKCSEPLVDLIYFWKD 291
+P E +Y+ D PV D+ WH TCF+CA C L ++ K
Sbjct: 544 EPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKK 603
Query: 292 GAPWCGRH 299
P C +H
Sbjct: 604 DRPLCKKH 611
Score = 30.0 bits (66), Expect = 3.4
Identities = 14/62 (22%), Positives = 25/62 (40%), Gaps = 1/62 (1%)
Query: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
R S P C C+ +I + +WH + F C C+ L+ ++ + + C
Sbjct: 431 RFPASSRTPLCGHCNNVIRGP-FLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 489
Query: 358 TC 359
C
Sbjct: 490 RC 491
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 70.9 bits (172), Expect = 2e-12
Identities = 33/91 (36%), Positives = 48/91 (52%), Gaps = 3/91 (3%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDL- 326
WH TCFVCA C +P + ++ +DG P+C + Y +C GCD + A D + +E L
Sbjct: 629 WHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGD-KFIEALG 687
Query: 327 -AWHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
WH F+C C L G+ + K + LC
Sbjct: 688 HTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718
Score = 53.9 bits (128), Expect = 2e-07
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 1/91 (1%)
Query: 266 KQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVED 325
+ WHP F CA C L D+ + + +C R Y + P C+ C+ I E +
Sbjct: 568 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQ 627
Query: 326 LAWHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
WH FVC C++ + + G+ C
Sbjct: 628 -TWHTTCFVCAACKKPFGNSLFHMEDGEPYC 657
Score = 36.6 bits (83), Expect = 0.036
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 2/68 (2%)
Query: 234 DPSKEVEYVCELCKGAAPPDSPVVYSDR--AGYNKQWHPTCFVCAKCSEPLVDLIYFWKD 291
+P E +Y+ D PV D+ WH TCF+CA C L ++ K
Sbjct: 654 EPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKK 713
Query: 292 GAPWCGRH 299
P C +H
Sbjct: 714 DRPLCKKH 721
Score = 30.0 bits (66), Expect = 3.4
Identities = 14/62 (22%), Positives = 25/62 (40%), Gaps = 1/62 (1%)
Query: 298 RHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCP 357
R S P C C+ +I + +WH + F C C+ L+ ++ + + C
Sbjct: 541 RFPASSRTPLCGHCNNVIRGP-FLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 599
Query: 358 TC 359
C
Sbjct: 600 RC 601
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 68.9 bits (167), Expect = 7e-12
Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Query: 253 DSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCD 312
+ P+ + WHP F C C EP D + ++G P+C R + + PRC GC
Sbjct: 291 NQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQ 350
Query: 313 EIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKR 364
I ++Y WH FVC C SG ++ +G+ LC ++R
Sbjct: 351 GPIL-DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARR 401
Score = 65.1 bits (157), Expect = 1e-10
Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 253 DSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCD 312
+ P+ + WHP FVC CS L +F KDGAP+C Y E PRC C+
Sbjct: 232 NKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCN 291
Query: 313 EIIFAEDYQRVEDLA--WHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
+ I ++ V L WH +HF C C + + +G+ C
Sbjct: 292 QPI---RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC 334
Score = 52.4 bits (124), Expect = 6e-07
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C+ C+G P++ + + + WHP CFVC +C P +F +G P C H+
Sbjct: 346 CQGCQG------PILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHA 399
Query: 303 SLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
C+ C + + +H HF C C + L+ ++ G+ C C
Sbjct: 400 RRGSLCATCGLPVTGRCVSAL-GRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 308 CSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
C C++ I + + AWH +HFVC GC L G ++ G CP C
Sbjct: 228 CGSCNKPIAGQVVTAL-GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 278
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 68.9 bits (167), Expect = 7e-12
Identities = 33/112 (29%), Positives = 50/112 (44%), Gaps = 1/112 (0%)
Query: 253 DSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCD 312
+ P+ + WHP F C C EP D + ++G P+C R + + PRC GC
Sbjct: 274 NQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQ 333
Query: 313 EIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKR 364
I ++Y WH FVC C SG ++ +G+ LC ++R
Sbjct: 334 GPIL-DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARR 384
Score = 65.1 bits (157), Expect = 1e-10
Identities = 34/106 (32%), Positives = 48/106 (45%), Gaps = 5/106 (4%)
Query: 253 DSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCD 312
+ P+ + WHP FVC CS L +F KDGAP+C Y E PRC C+
Sbjct: 215 NKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCN 274
Query: 313 EIIFAEDYQRVEDLA--WHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
+ I ++ V L WH +HF C C + + +G+ C
Sbjct: 275 QPI---RHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYC 317
Score = 52.4 bits (124), Expect = 6e-07
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 7/117 (5%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
C+ C+G P++ + + + WHP CFVC +C P +F +G P C H+
Sbjct: 329 CQGCQG------PILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHA 382
Query: 303 SLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
C+ C + + +H HF C C + L+ ++ G+ C C
Sbjct: 383 RRGSLCATCGLPVTGRCVSAL-GRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438
Score = 41.6 bits (96), Expect = 0.001
Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 308 CSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
C C++ I + + AWH +HFVC GC L G ++ G CP C
Sbjct: 211 CGSCNKPIAGQVVTAL-GRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPEC 261
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 68.6 bits (166), Expect = 9e-12
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAED-YQRVEDL 326
WH CF CA C P+ + ++ ++G P+C R Y + +C GCD I A D +
Sbjct: 326 WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGF 385
Query: 327 AWHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
+WH FVC C+ L G+ + K + LC
Sbjct: 386 SWHDTCFVCAICQINLEGKTFYSKKDRPLC 415
Score = 50.8 bits (120), Expect = 2e-06
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLA 327
+HP FVC++C + L + +F + GA +C Y P C+ C + I E ++ +
Sbjct: 267 YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALK-MT 325
Query: 328 WHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
WH F C C+ + RA+ + +G C
Sbjct: 326 WHVHCFTCAACKTPIRNRAFYMEEGVPYC 354
Score = 35.8 bits (81), Expect = 0.062
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 306 PRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
P C C ++I Y A+H + FVC C ++L + KG + CP C
Sbjct: 246 PVCHQCHKVIRGR-YLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 298
Score = 34.7 bits (78), Expect = 0.14
Identities = 14/32 (43%), Positives = 16/32 (50%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRH 299
WH TCFVCA C L ++ K P C H
Sbjct: 387 WHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 418
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 68.6 bits (166), Expect = 9e-12
Identities = 31/90 (34%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAED-YQRVEDL 326
WH CF CA C P+ + ++ ++G P+C R Y + +C GCD I A D +
Sbjct: 360 WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGF 419
Query: 327 AWHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
+WH FVC C+ L G+ + K + LC
Sbjct: 420 SWHDTCFVCAICQINLEGKTFYSKKDRPLC 449
Score = 50.8 bits (120), Expect = 2e-06
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 1/89 (1%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLA 327
+HP FVC++C + L + +F + GA +C Y P C+ C + I E ++ +
Sbjct: 301 YHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALK-MT 359
Query: 328 WHRKHFVCEGCEQLLSGRAYIVTKGQLLC 356
WH F C C+ + RA+ + +G C
Sbjct: 360 WHVHCFTCAACKTPIRNRAFYMEEGVPYC 388
Score = 35.8 bits (81), Expect = 0.062
Identities = 17/54 (31%), Positives = 25/54 (46%), Gaps = 1/54 (1%)
Query: 306 PRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTC 359
P C C ++I Y A+H + FVC C ++L + KG + CP C
Sbjct: 280 PVCHQCHKVIRGR-YLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 332
Score = 34.7 bits (78), Expect = 0.14
Identities = 14/32 (43%), Positives = 16/32 (50%)
Query: 268 WHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRH 299
WH TCFVCA C L ++ K P C H
Sbjct: 421 WHDTCFVCAICQINLEGKTFYSKKDRPLCKSH 452
>gi|239741720 PREDICTED: hypothetical protein XP_002342298 [Homo
sapiens]
Length = 248
Score = 68.2 bits (165), Expect = 1e-11
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
CE CKG P +V S+ Y++Q CFVCA+C + + +++ +G +C +
Sbjct: 72 CERCKGGFAPAETIVNSNGELYHEQ----CFVCAQCFQQFPEGLFYEFEGRKYCEHDFQM 127
Query: 303 SLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
P C C E I + + + +WH + F C+ C+++L+ ++ G+ LC C
Sbjct: 128 LFAPCCHQCGEFIIGRVIKAMNN-SWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 186
Query: 363 KRS 365
+++
Sbjct: 187 EKA 189
>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
sapiens]
Length = 325
Score = 68.2 bits (165), Expect = 1e-11
Identities = 33/123 (26%), Positives = 62/123 (50%), Gaps = 5/123 (4%)
Query: 243 CELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCE 302
CE CKG P +V S+ Y++Q CFVCA+C + + +++ +G +C +
Sbjct: 10 CERCKGGFAPAEKIVNSNGELYHEQ----CFVCAQCFQQFPEGLFYEFEGRKYCEHDFQM 65
Query: 303 SLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKS 362
P C C E I + + + +WH + F C+ C+++L+ ++ G+ LC C
Sbjct: 66 LFAPCCHQCGEFIIGRVIKAMNN-SWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNR 124
Query: 363 KRS 365
+++
Sbjct: 125 EKA 127
Score = 50.4 bits (119), Expect = 2e-06
Identities = 30/102 (29%), Positives = 45/102 (44%), Gaps = 7/102 (6%)
Query: 242 VCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYC 301
+C C+ P + VV + KQWH FVCAKC +P + ++ + G +C HY
Sbjct: 192 ICGACR--RPIEGRVVNA----MGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYN 245
Query: 302 ESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLS 343
+ C C+ +I D + AW F C C L+
Sbjct: 246 QLFGDVCFHCNRVI-EGDVVSALNKAWCVNCFACSTCNTKLT 286
Score = 47.8 bits (112), Expect = 2e-05
Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 18/124 (14%)
Query: 240 EYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRH 299
+Y+C+ C A + P+++ N +HP F CA C + L D G
Sbjct: 132 KYICQKCH-AIIDEQPLIFK-----NDPYHPDHFNCANCGKELT------ADARELKGEL 179
Query: 300 YCESLR-----PRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQL 354
YC P C C I + WH +HFVC CE+ G + KG
Sbjct: 180 YCLPCHDKMGVPICGACRRPIEGRVVNAMGK-QWHVEHFVCAKCEKPFLGHRHYERKGLA 238
Query: 355 LCPT 358
C T
Sbjct: 239 YCET 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,458,591
Number of Sequences: 37866
Number of extensions: 823281
Number of successful extensions: 3506
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 87
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 2956
Number of HSP's gapped (non-prelim): 352
length of query: 365
length of database: 18,247,518
effective HSP length: 104
effective length of query: 261
effective length of database: 14,309,454
effective search space: 3734767494
effective search space used: 3734767494
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.