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Search of human proteins with 7657269
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657269 PDS5, regulator of cohesion maintenance, homolog B
[Homo sapiens]
(1447 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [H... 2876 0.0
gi|155030216 PDS5, regulator of cohesion maintenance, homolog A ... 1831 0.0
gi|155030218 PDS5, regulator of cohesion maintenance, homolog A ... 1797 0.0
gi|155030220 PDS5, regulator of cohesion maintenance, homolog A ... 960 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 65 6e-10
gi|104526627 triadin [Homo sapiens] 64 1e-09
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 62 3e-09
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 62 4e-09
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 60 1e-08
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 60 2e-08
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 60 2e-08
gi|117676384 splicing factor, arginine/serine-rich 2, interactin... 60 2e-08
gi|87299628 biorientation of chromosomes in cell division 1-like... 60 2e-08
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens] 60 2e-08
gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo... 59 3e-08
gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo ... 59 3e-08
gi|4557509 cylicin 2 [Homo sapiens] 58 6e-08
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 58 8e-08
gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo... 57 1e-07
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens] 57 1e-07
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 57 1e-07
gi|48255931 hepatoma-derived growth factor-related protein 2 iso... 57 2e-07
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 57 2e-07
gi|14249158 hepatoma-derived growth factor-related protein 2 iso... 57 2e-07
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 55 4e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 55 5e-07
gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sap... 55 5e-07
gi|50962882 G patch domain containing 8 [Homo sapiens] 55 5e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 55 6e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 55 6e-07
>gi|7657269 PDS5, regulator of cohesion maintenance, homolog B [Homo
sapiens]
Length = 1447
Score = 2876 bits (7455), Expect = 0.0
Identities = 1447/1447 (100%), Positives = 1447/1447 (100%)
Query: 1 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 60
MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA
Sbjct: 1 MAHSKTRTNDGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLA 60
Query: 61 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 120
LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT
Sbjct: 61 LHLASDFFLKHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDT 120
Query: 121 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 180
KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL
Sbjct: 121 KSPQFNRYFYLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDL 180
Query: 181 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 240
MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV
Sbjct: 181 MSSIICEGDTVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQV 240
Query: 241 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 300
LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF
Sbjct: 241 LMLGKTSISDLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMF 300
Query: 301 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 360
GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH
Sbjct: 301 GAKDSELASQNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSH 360
Query: 361 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 420
DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA
Sbjct: 361 DPEEAIRHDVIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYA 420
Query: 421 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 480
LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL
Sbjct: 421 LQSAAGKDAAKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYL 480
Query: 481 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 540
YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG
Sbjct: 481 YATLDLNAVKALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPG 540
Query: 541 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 600
KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM
Sbjct: 541 KAQDFMKKFTQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEM 600
Query: 601 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 660
IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH
Sbjct: 601 IKFLLERIAPVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTH 660
Query: 661 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 720
PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK
Sbjct: 661 PISFHSAETFESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKK 720
Query: 721 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 780
GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ
Sbjct: 721 GPPRQAKYAIHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQ 780
Query: 781 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 840
FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK
Sbjct: 781 FAAPLKSLVATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMK 840
Query: 841 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 900
NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT
Sbjct: 841 NNHSKSGTSTLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIIT 900
Query: 901 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 960
LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ
Sbjct: 901 LEQYQLCALAINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQ 960
Query: 961 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 1020
CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC
Sbjct: 961 CLVKNINVRREYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKEC 1020
Query: 1021 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1080
LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS
Sbjct: 1021 LWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKS 1080
Query: 1081 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1140
TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS
Sbjct: 1081 TTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSS 1140
Query: 1141 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1200
AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK
Sbjct: 1141 AGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDK 1200
Query: 1201 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1260
RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD
Sbjct: 1201 RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD 1260
Query: 1261 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1320
EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG
Sbjct: 1261 EQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSG 1320
Query: 1321 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1380
PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK
Sbjct: 1321 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1380
Query: 1381 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1440
TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR
Sbjct: 1381 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1440
Query: 1441 SAKRERR 1447
SAKRERR
Sbjct: 1441 SAKRERR 1447
>gi|155030216 PDS5, regulator of cohesion maintenance, homolog A
isoform 1 [Homo sapiens]
Length = 1337
Score = 1832 bits (4744), Expect = 0.0
Identities = 916/1321 (69%), Positives = 1083/1321 (81%), Gaps = 28/1321 (2%)
Query: 10 DGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFL 69
DGKI YPPGVKEI+DKI+ +EM++RLKMVVKTFMDMDQDSE+EK+ YL LALHLAS+FFL
Sbjct: 20 DGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFL 79
Query: 70 KHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYF 129
++P+KDVRLLVACCLADIFRIYAPEAPYTS DKLKDIF+FITRQLKGLEDTKSPQFNRYF
Sbjct: 80 RNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYF 139
Query: 130 YLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGD 189
YLLEN+AWVKSYNICFELED NEIF QL+RTLFSVINN HN+KV MHM+DLMSSII EGD
Sbjct: 140 YLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGD 199
Query: 190 TVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSIS 249
V+QELLD++L+NL+PAHKNLNKQ++DLAK LLKRT Q IE I NFFNQVL+LG++S+S
Sbjct: 200 GVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVS 259
Query: 250 DLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELAS 309
DLSEHVFDLI EL+ ID HLLLSV+PQLEFKLKSND EERL VV+LLAK+FG+KDS+LA+
Sbjct: 260 DLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLAT 319
Query: 310 QNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHD 369
QN+PLWQC+LGRFNDIHVP+RLE VKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHD
Sbjct: 320 QNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHD 379
Query: 370 VIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDA 429
VIV+I+TAAK+D+ LVND LL FVRERTLDKRWRVRKEAMMGLAQ+YKKY L AGK+A
Sbjct: 380 VIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEA 439
Query: 430 AKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAV 489
A++++WIKDKLLHIYYQNSIDD+LLVE+IFAQY+VPHNLET ERMKCLYYLYA+LD NAV
Sbjct: 440 AEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAV 499
Query: 490 KALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKF 549
KALNEMWKCQN+LR V++LLDL KQP ++A+ A+F K+M I +NLPDPGKAQDF+KKF
Sbjct: 500 KALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKF 559
Query: 550 TQVLEDDEKIRKQLEVLVSPTCSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLERIA 609
QVL DDEK+R QLE+L+SPTCSCKQA+ CVREI +KL NPKQPTNPFLEM+KFLLERIA
Sbjct: 560 NQVLGDDEKLRSQLELLISPTCSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIA 619
Query: 610 PVHIDTESISALIKQVNKSIDGTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAET 669
PVHID+E+ISAL+K +NKSI+GTADDE+EGV D AIR+GLELLKVLSFTHP SFHSAET
Sbjct: 620 PVHIDSEAISALVKLMNKSIEGTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAET 679
Query: 670 FESLLACLKMDDEKVAEAALQIFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYA 729
+ESLL CL+M+D+KVAEAA+QIF+NTG KIE D P IRS L+P+LH K+K+G P QAK A
Sbjct: 680 YESLLQCLRMEDDKVAEAAIQIFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQA 739
Query: 730 IHCIHAIFSSKETQFAQIFEPLHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLV 789
+HCIHAIF++KE Q AQIFEPL +SL+ E LITPLV++GHI++LAPDQFA+P+KS+V
Sbjct: 740 VHCIHAIFTNKEVQLAQIFEPLSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVV 799
Query: 790 ATFIVKDLLMNDRLPGKKTTKLWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTS 849
A FIVKDLLMNDR G+K KLW PDEEVSPE + K+QAIK++VRWLLGMKNN SKS S
Sbjct: 800 ANFIVKDLLMNDRSTGEKNGKLWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANS 859
Query: 850 TLRLLTTILHSDGDLTEQGKISKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCAL 909
TLRLL+ +L S+GDLTEQ +ISK DMSRLRLAAGSAI+KLAQEPCYHEIIT EQ+QLCAL
Sbjct: 860 TLRLLSAMLVSEGDLTEQKRISKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCAL 919
Query: 910 AINDECYQVRQVFAQKLHKGLSRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNINVR 969
INDECYQVRQ+FAQKLHK L +L LPLEYMAI ALCAKDPVKERRAHARQCL+KNI++R
Sbjct: 920 VINDECYQVRQIFAQKLHKALVKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIR 979
Query: 970 REYLKQHAAVSEKLLSLLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILM 1029
REY+KQ+ +EKLLSLLPEYVVPY IHLLAHDPD+ + QD++QL+D+KECLWF+LE+LM
Sbjct: 980 REYIKQNPMATEKLLSLLPEYVVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLM 1039
Query: 1030 AKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPK 1089
KNENNSHAF++KM ENIK T+DAQ PD++K NEKLYTVCDVA+ +I SKS + +SPK
Sbjct: 1040 TKNENNSHAFMKKMAENIKLTRDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPK 1099
Query: 1090 DPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKS 1149
DPVLP +FFTQP+K+F N K+Y+ E + GKPK VLGAVNKPLS+ G++ +S
Sbjct: 1100 DPVLPMKFFTQPEKDFCNDKSYISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRS 1159
Query: 1150 SRMETVS--NASSSSNPSSPGRIKGR-LDSSEMDHSENED--YTMSSPLPGKKSD----K 1200
+ ET S N +S NPS+ R + + +++E SENE+ + S P K D K
Sbjct: 1160 TGTETGSNINVNSELNPSTGNRSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNK 1219
Query: 1201 RDDSD-LVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASES 1259
+SD + + RG+K+T E + + V E P + R+ SES
Sbjct: 1220 EINSDQATQGNISSDRGKKRTVTAAGAENI-QQKTDEKVDESGPPAPSKPRRGRRPKSES 1278
Query: 1260 DEQQWPEEKRLKEDILENEDEQNSPPKKGKR-----GRPPKPLGGGTPKEEPTMKTSKKG 1314
+ D+ N P KG++ P L G K +KK
Sbjct: 1279 ------------QGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKA 1326
Query: 1315 S 1315
+
Sbjct: 1327 A 1327
>gi|155030218 PDS5, regulator of cohesion maintenance, homolog A
isoform 2 [Homo sapiens]
Length = 1297
Score = 1797 bits (4655), Expect = 0.0
Identities = 900/1300 (69%), Positives = 1064/1300 (81%), Gaps = 28/1300 (2%)
Query: 31 MVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFLKHPDKDVRLLVACCLADIFRI 90
M++RLKMVVKTFMDMDQDSE+EK+ YL LALHLAS+FFL++P+KDVRLLVACCLADIFRI
Sbjct: 1 MIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFLRNPNKDVRLLVACCLADIFRI 60
Query: 91 YAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYFYLLENIAWVKSYNICFELEDS 150
YAPEAPYTS DKLKDIF+FITRQLKGLEDTKSPQFNRYFYLLEN+AWVKSYNICFELED
Sbjct: 61 YAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYFYLLENLAWVKSYNICFELEDC 120
Query: 151 NEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNL 210
NEIF QL+RTLFSVINN HN+KV MHM+DLMSSII EGD V+QELLD++L+NL+PAHKNL
Sbjct: 121 NEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGDGVTQELLDSILINLIPAHKNL 180
Query: 211 NKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSISDLSEHVFDLILELYNIDSHLL 270
NKQ++DLAK LLKRT Q IE I NFFNQVL+LG++S+SDLSEHVFDLI EL+ ID HLL
Sbjct: 181 NKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVSDLSEHVFDLIQELFAIDPHLL 240
Query: 271 LSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELASQNKPLWQCYLGRFNDIHVPIR 330
LSV+PQLEFKLKSND EERL VV+LLAK+FG+KDS+LA+QN+PLWQC+LGRFNDIHVP+R
Sbjct: 241 LSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLATQNRPLWQCFLGRFNDIHVPVR 300
Query: 331 LECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVSIVTAAKKDILLVNDHLL 390
LE VKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIV+I+TAAK+D+ LVND LL
Sbjct: 301 LESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHDVIVTIITAAKRDLALVNDQLL 360
Query: 391 NFVRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDAAKQIAWIKDKLLHIYYQNSID 450
FVRERTLDKRWRVRKEAMMGLAQ+YKKY L AGK+AA++++WIKDKLLHIYYQNSID
Sbjct: 361 GFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEAAEKVSWIKDKLLHIYYQNSID 420
Query: 451 DRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAVKALNEMWKCQNLLRHQVKDLL 510
D+LLVE+IFAQY+VPHNLET ERMKCLYYLYA+LD NAVKALNEMWKCQN+LR V++LL
Sbjct: 421 DKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAVKALNEMWKCQNMLRSHVRELL 480
Query: 511 DLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKFTQVLEDDEKIRKQLEVLVSPT 570
DL KQP ++A+ A+F K+M I +NLPDPGKAQDF+KKF QVL DDEK+R QLE+L+SPT
Sbjct: 481 DLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKFNQVLGDDEKLRSQLELLISPT 540
Query: 571 CSCKQAEGCVREITKKLGNPKQPTNPFLEMIKFLLERIAPVHIDTESISALIKQVNKSID 630
CSCKQA+ CVREI +KL NPKQPTNPFLEM+KFLLERIAPVHID+E+ISAL+K +NKSI+
Sbjct: 541 CSCKQADICVREIARKLANPKQPTNPFLEMVKFLLERIAPVHIDSEAISALVKLMNKSIE 600
Query: 631 GTADDEDEGVPTDQAIRAGLELLKVLSFTHPISFHSAETFESLLACLKMDDEKVAEAALQ 690
GTADDE+EGV D AIR+GLELLKVLSFTHP SFHSAET+ESLL CL+M+D+KVAEAA+Q
Sbjct: 601 GTADDEEEGVSPDTAIRSGLELLKVLSFTHPTSFHSAETYESLLQCLRMEDDKVAEAAIQ 660
Query: 691 IFKNTGSKIEEDFPHIRSALLPVLHHKSKKGPPRQAKYAIHCIHAIFSSKETQFAQIFEP 750
IF+NTG KIE D P IRS L+P+LH K+K+G P QAK A+HCIHAIF++KE Q AQIFEP
Sbjct: 661 IFRNTGHKIETDLPQIRSTLIPILHQKAKRGTPHQAKQAVHCIHAIFTNKEVQLAQIFEP 720
Query: 751 LHKSLDPSNLEHLITPLVTIGHIALLAPDQFAAPLKSLVATFIVKDLLMNDRLPGKKTTK 810
L +SL+ E LITPLV++GHI++LAPDQFA+P+KS+VA FIVKDLLMNDR G+K K
Sbjct: 721 LSRSLNADVPEQLITPLVSLGHISMLAPDQFASPMKSVVANFIVKDLLMNDRSTGEKNGK 780
Query: 811 LWVPDEEVSPETMVKIQAIKMMVRWLLGMKNNHSKSGTSTLRLLTTILHSDGDLTEQGKI 870
LW PDEEVSPE + K+QAIK++VRWLLGMKNN SKS STLRLL+ +L S+GDLTEQ +I
Sbjct: 781 LWSPDEEVSPEVLAKVQAIKLLVRWLLGMKNNQSKSANSTLRLLSAMLVSEGDLTEQKRI 840
Query: 871 SKPDMSRLRLAAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVRQVFAQKLHKGL 930
SK DMSRLRLAAGSAI+KLAQEPCYHEIIT EQ+QLCAL INDECYQVRQ+FAQKLHK L
Sbjct: 841 SKSDMSRLRLAAGSAIMKLAQEPCYHEIITPEQFQLCALVINDECYQVRQIFAQKLHKAL 900
Query: 931 SRLRLPLEYMAICALCAKDPVKERRAHARQCLVKNINVRREYLKQHAAVSEKLLSLLPEY 990
+L LPLEYMAI ALCAKDPVKERRAHARQCL+KNI++RREY+KQ+ +EKLLSLLPEY
Sbjct: 901 VKLLLPLEYMAIFALCAKDPVKERRAHARQCLLKNISIRREYIKQNPMATEKLLSLLPEY 960
Query: 991 VVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQT 1050
VVPY IHLLAHDPD+ + QD++QL+D+KECLWF+LE+LM KNENNSHAF++KM ENIK T
Sbjct: 961 VVPYMIHLLAHDPDFTRSQDVDQLRDIKECLWFMLEVLMTKNENNSHAFMKKMAENIKLT 1020
Query: 1051 KDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKN 1110
+DAQ PD++K NEKLYTVCDVA+ +I SKS + +SPKDPVLP +FFTQP+K+F N K+
Sbjct: 1021 RDAQSPDESKTNEKLYTVCDVALCVINSKSALCNADSPKDPVLPMKFFTQPEKDFCNDKS 1080
Query: 1111 YLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVS--NASSSSNPSSPG 1168
Y+ E + GKPK VLGAVNKPLS+ G++ +S+ ET S N +S NPS+
Sbjct: 1081 YISEETRVLLLTGKPKPAGVLGAVNKPLSATGRKPYVRSTGTETGSNINVNSELNPSTGN 1140
Query: 1169 RIKGR-LDSSEMDHSENED--YTMSSPLPGKKSD----KRDDSD-LVRSELEKPRGRKKT 1220
R + + +++E SENE+ + S P K D K +SD + + RG+K+T
Sbjct: 1141 RSREQSSEAAETGVSENEENPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRT 1200
Query: 1221 PVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDE 1280
E + + V E P + R+ SES + D+
Sbjct: 1201 VTAAGAENI-QQKTDEKVDESGPPAPSKPRRGRRPKSES------------QGNATKNDD 1247
Query: 1281 QNSPPKKGKR-----GRPPKPLGGGTPKEEPTMKTSKKGS 1315
N P KG++ P L G K +KK +
Sbjct: 1248 LNKPINKGRKRAAVGQESPGGLEAGNAKAPKLQDLAKKAA 1287
>gi|155030220 PDS5, regulator of cohesion maintenance, homolog A
isoform 3 [Homo sapiens]
Length = 600
Score = 960 bits (2481), Expect = 0.0
Identities = 461/571 (80%), Positives = 526/571 (92%)
Query: 10 DGKITYPPGVKEISDKISKEEMVRRLKMVVKTFMDMDQDSEEEKELYLNLALHLASDFFL 69
DGKI YPPGVKEI+DKI+ +EM++RLKMVVKTFMDMDQDSE+EK+ YL LALHLAS+FFL
Sbjct: 20 DGKIAYPPGVKEITDKITTDEMIKRLKMVVKTFMDMDQDSEDEKQQYLPLALHLASEFFL 79
Query: 70 KHPDKDVRLLVACCLADIFRIYAPEAPYTSPDKLKDIFMFITRQLKGLEDTKSPQFNRYF 129
++P+KDVRLLVACCLADIFRIYAPEAPYTS DKLKDIF+FITRQLKGLEDTKSPQFNRYF
Sbjct: 80 RNPNKDVRLLVACCLADIFRIYAPEAPYTSHDKLKDIFLFITRQLKGLEDTKSPQFNRYF 139
Query: 130 YLLENIAWVKSYNICFELEDSNEIFTQLYRTLFSVINNGHNQKVHMHMVDLMSSIICEGD 189
YLLEN+AWVKSYNICFELED NEIF QL+RTLFSVINN HN+KV MHM+DLMSSII EGD
Sbjct: 140 YLLENLAWVKSYNICFELEDCNEIFIQLFRTLFSVINNSHNKKVQMHMLDLMSSIIMEGD 199
Query: 190 TVSQELLDTVLVNLVPAHKNLNKQAYDLAKALLKRTAQAIEPYITNFFNQVLMLGKTSIS 249
V+QELLD++L+NL+PAHKNLNKQ++DLAK LLKRT Q IE I NFFNQVL+LG++S+S
Sbjct: 200 GVTQELLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQTIEACIANFFNQVLVLGRSSVS 259
Query: 250 DLSEHVFDLILELYNIDSHLLLSVLPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELAS 309
DLSEHVFDLI EL+ ID HLLLSV+PQLEFKLKSND EERL VV+LLAK+FG+KDS+LA+
Sbjct: 260 DLSEHVFDLIQELFAIDPHLLLSVMPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLAT 319
Query: 310 QNKPLWQCYLGRFNDIHVPIRLECVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHD 369
QN+PLWQC+LGRFNDIHVP+RLE VKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHD
Sbjct: 320 QNRPLWQCFLGRFNDIHVPVRLESVKFASHCLMNHPDLAKDLTEYLKVRSHDPEEAIRHD 379
Query: 370 VIVSIVTAAKKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQIYKKYALQSAAGKDA 429
VIV+I+TAAK+D+ LVND LL FVRERTLDKRWRVRKEAMMGLAQ+YKKY L AGK+A
Sbjct: 380 VIVTIITAAKRDLALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQLYKKYCLHGEAGKEA 439
Query: 430 AKQIAWIKDKLLHIYYQNSIDDRLLVERIFAQYMVPHNLETTERMKCLYYLYATLDLNAV 489
A++++WIKDKLLHIYYQNSIDD+LLVE+IFAQY+VPHNLET ERMKCLYYLYA+LD NAV
Sbjct: 440 AEKVSWIKDKLLHIYYQNSIDDKLLVEKIFAQYLVPHNLETEERMKCLYYLYASLDPNAV 499
Query: 490 KALNEMWKCQNLLRHQVKDLLDLIKQPKTDASVKAIFSKVMVITRNLPDPGKAQDFMKKF 549
KALNEMWKCQN+LR V++LLDL KQP ++A+ A+F K+M I +NLPDPGKAQDF+KKF
Sbjct: 500 KALNEMWKCQNMLRSHVRELLDLHKQPTSEANCSAMFGKLMTIAKNLPDPGKAQDFVKKF 559
Query: 550 TQVLEDDEKIRKQLEVLVSPTCSCKQAEGCV 580
QVL DDEK+R QLE+L+SPTCSCKQA+ CV
Sbjct: 560 NQVLGDDEKLRSQLELLISPTCSCKQADICV 590
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 64.7 bits (156), Expect = 6e-10
Identities = 81/413 (19%), Positives = 167/413 (40%), Gaps = 26/413 (6%)
Query: 1051 KDAQGPDDAKMNEKLYT-VCDVAMNIIMSKSTTYS-LESPKDPVLPARFFTQPDKNFSNT 1108
++A+ P +AK EK + V + A + +KS +SP + P + + + +
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP 649
Query: 1109 KNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKS---SRMETVSNASSSSNPS 1165
+ PE + +P K K+ A + + + +++ KS ++ A S
Sbjct: 650 EKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAK 709
Query: 1166 SPGRIKGRLDSSEMDHSENEDYT---MSSPLPGK-KSDKRDDSDLVRSELEKPRGRKKTP 1221
SP + + + + E T SP+ + KS ++ S L+ KTP
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 769
Query: 1222 VTEQEEKLG--MDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENED 1279
E+ + K +++ K ++++ +++ E++ P+++ +K + E E
Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 1280 EQN----SPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGP-PAPEEEEEEERQS 1334
Q PPKK + + P TPK E + K+ + KK P P EE++E +
Sbjct: 830 PQEVKVKEPPKKAEEEKAP-----ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 1335 GNTEQKSKSKQHRVSRRAQQRAESPESSAIE-STQSTPQKGRGRPSKTPSPSQPKKNVRV 1393
+ K+ ++ E + +E + P++ K P ++ K+ +
Sbjct: 885 PKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944
Query: 1394 GRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRER 1446
K+AA ++ D+ EE + P + E +E+ T++ K E+
Sbjct: 945 AEKKEAAPEKKDTKEE----KAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEK 993
Score = 58.5 bits (140), Expect = 4e-08
Identities = 121/595 (20%), Positives = 225/595 (37%), Gaps = 56/595 (9%)
Query: 881 AAGSAIVKLAQEPCYHEIITLEQYQLCALAINDECYQVR--------QVFAQKLHKGLSR 932
AA A+ + AQE + Q A A+ +EC +R ++ Q G ++
Sbjct: 197 AAARALARFAQEAEAARV----DLQKKAQALQEECGYLRRHHQEEVGELLGQIQGSGAAQ 252
Query: 933 LRLPLEYMAICALCAKDPVKERRA----HARQCLVKN---INVRREYLKQHAAVSEKLLS 985
++ E ++E RA HA Q +++ VR + L + A V+ +
Sbjct: 253 AQMQAETRDALKCDVTSALREIRAQLEGHAVQSTLQSEEWFRVRLDRLSEAAKVNTDAMR 312
Query: 986 LLPEYVVPYTIHLLAHDPDYVKVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVE 1045
E + Y L A + ++E LK K+ L E ++ E+ A I E
Sbjct: 313 SAQEEITEYRRQLQA------RTTELEALKSTKDSL----ERQRSELEDRHQADIASYQE 362
Query: 1046 NIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNF 1105
I+Q +M +L D+ +N+ M+ + R P F
Sbjct: 363 AIQQLDAELRNTKWEMAAQLREYQDL-LNVKMALDIEIAAYRKLLEGEECRIGFGPIP-F 420
Query: 1106 SNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKP-LSSAGKQSQTKSSRM-ETVSNASSSSN 1163
S + P++ S T K K+ + V K + + QT+ +++ E V+
Sbjct: 421 SLPEGL--PKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEA 478
Query: 1164 PSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVT 1223
G+ + + E + E E T S P S +++ V+ E + P K+P
Sbjct: 479 KEEEGKEEEGGEEEEAEGGEEE--TKSPPAEEAASPEKEAKSPVKEEAKSP-AEAKSP-- 533
Query: 1224 EQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNS 1283
E+EE ++ + + P + + E +E + P E + E E+
Sbjct: 534 EKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 593
Query: 1284 PPKKGKRGRPPK---------PLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQS 1334
P + K K P +P +E ++ S +K+ P EE + E+
Sbjct: 594 SPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653
Query: 1335 GNTEQKSKSKQHRVSRRAQQRAESPES--SAIESTQSTPQKGRGR-PSKTPSPSQPKKNV 1391
++++KS + + + A+SPE S +++ +P+K + + SP + K V
Sbjct: 654 SPEKEEAKSPE-KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPV 712
Query: 1392 RVGRSKQAATKENDSSEEVDVFQGSSPVDD---IPQEETEEEEVSTVNVRRRSAK 1443
+ K E + SPV + P++ E+ T++V+ AK
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAK 767
Score = 53.5 bits (127), Expect = 1e-06
Identities = 71/327 (21%), Positives = 123/327 (37%), Gaps = 38/327 (11%)
Query: 1079 KSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPL 1138
K S E K PV + K+ + P + KS P K KT +V
Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS---PEKAKTLDV-------- 761
Query: 1139 SSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKS 1198
K + K+ E + + + +K + S E S ++ + P K+
Sbjct: 762 ----KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE---DAKAPEKEI 814
Query: 1199 DKRDDSDLVRSELEKPRGRK--KTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTA 1256
K+++ E EKP+ K + P +EEK T +E+K + + K+
Sbjct: 815 PKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA---PATPKTEEKKDSKKEEAPKKEAPK 871
Query: 1257 SESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPL-----GGGTPKE------- 1304
+ +E++ P ++ KE +E + E+ KK P PKE
Sbjct: 872 PKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKK 931
Query: 1305 EPTMKTSKKGSK---KKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPES 1361
EP +K+ SK KK P ++ +EE+ + + K+++K + + P++
Sbjct: 932 EPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKA 991
Query: 1362 SAIESTQSTPQKGRGRPSKTPSPSQPK 1388
E + ST QK P K K
Sbjct: 992 EKAEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 44.7 bits (104), Expect = 7e-04
Identities = 60/297 (20%), Positives = 108/297 (36%), Gaps = 29/297 (9%)
Query: 1140 SAGKQSQTKSSRMETVSNASSSSNPS-----SPGRIKGRLDSSEMDHSENEDYTMSSPLP 1194
+A + + KS E + + + +P SP +K S E S ++ S P
Sbjct: 509 AASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK----SPEKAKSPAKEEAKSPPEA 564
Query: 1195 GKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGH 1254
+ S EK + K E + V+E+ ++
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 1255 TASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKG 1314
A E + PE+ + E+ P+K + P K + P +K
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK-------AKSPVKAEAKSP 677
Query: 1315 SKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPE--SSAIESTQSTPQ 1372
K KS P E + E+ ++++KS + + ++ A+SPE S ++ TP+
Sbjct: 678 EKAKS--PVKAEAKSPEKAKSPVKEEAKSPE-KAKSPVKEEAKSPEKAKSPVKEEAKTPE 734
Query: 1373 KGRG-------RPSKTPSPSQPKK-NVRVGRSKQAATKENDSSEEVDVFQGSSPVDD 1421
K + P K SP + K +V+ +K A +E S + + SPV +
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKE 791
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 63.5 bits (153), Expect = 1e-09
Identities = 58/260 (22%), Positives = 119/260 (45%), Gaps = 16/260 (6%)
Query: 1197 KSDKRDDSDLVRSELEKPRGRKKT---PVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRG 1253
+ D D D + E+++P RKK TE++EK TK+ ++K KG ++ R++
Sbjct: 119 EEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKE 178
Query: 1254 HTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKK 1313
++ ++ E+K E ++++ + + + K + GG K+E +T+ K
Sbjct: 179 KPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGG--KQEKVKQTAAK 236
Query: 1314 GSKKKSGPPAPEEEEEEERQS-GNTEQKSKSK--QHRVSRRAQQRAESPESSAIESTQST 1370
+ + P P+E+E++E+ + EQK + ++ + + +S AI T
Sbjct: 237 VKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPT 296
Query: 1371 PQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETE-- 1428
Q R P+ SP+ +K ++++ T E E+ D+ + S I E+ E
Sbjct: 297 EQASRPTPA---SPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353
Query: 1429 ---EEEVSTVNVRRRSAKRE 1445
E + TV + ++A ++
Sbjct: 354 KASETKQGTVKIAAQAAAKK 373
Score = 53.9 bits (128), Expect = 1e-06
Identities = 67/359 (18%), Positives = 136/359 (37%), Gaps = 36/359 (10%)
Query: 1112 LPPEMKSFFTPGKPKTTNVLGA---VNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPG 1168
LP E S TP P G K ++S K+ + + + ++ + PG
Sbjct: 294 LPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353
Query: 1169 RIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVR--SELEKPRGRKKTPVTEQE 1226
+ ++ +++ KK +K++DS + +E+E+P+G+K+ +
Sbjct: 354 KAS---------ETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHV 404
Query: 1227 EKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWP---EEKRLK---EDILENEDE 1280
E V K ++ R + + S ++ P EEK K ++I + +
Sbjct: 405 EPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSG 464
Query: 1281 QNSP------PKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPP--------APEE 1326
+ S P KGK + P L P+ + K SK G + K PP PE
Sbjct: 465 KTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEP 524
Query: 1327 EEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQ 1386
+ ++E + +E+ KQ V PE ++ ++ + +P T
Sbjct: 525 QIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEH 584
Query: 1387 PKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRE 1445
++ ++ + +SE + G + +E E+ ++ + + S ++E
Sbjct: 585 REREPPSIKTDKPKPTPKGTSEVTE--SGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
Score = 44.3 bits (103), Expect = 9e-04
Identities = 61/302 (20%), Positives = 118/302 (39%), Gaps = 61/302 (20%)
Query: 1142 GKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKR 1201
GK+ + K +E + + S ++K + + ++ E ++ +PGKK +K
Sbjct: 394 GKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAK---EEIGAVSIKKAVPGKKEEKT 450
Query: 1202 DDSDLVRSELEKPRGRK-------KTPVTEQEEKLGM------------DDLTKLVQEQK 1242
+ V E+ K + K K P+ +EEK+ + ++K +E K
Sbjct: 451 TKT--VEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVK 508
Query: 1243 PKGSQRSRKRGHTASESDEQQWPEEKR--LKEDILENEDEQNSPPKKGKRGRP------- 1293
PK Q K+ E E Q +E + + E + ++ + P K G+P
Sbjct: 509 PKPPQLQGKK----EEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQ 564
Query: 1294 -----------PKPLGGGTPKEE--PTMKTSK-----KGSKK--KSGPPAPEEEEEEERQ 1333
PKP +E P++KT K KG+ + +SG E E+E ++
Sbjct: 565 VKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKE 624
Query: 1334 SGNT----EQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKK 1389
+ E+K +++ + +AE P + + K ++ SP++ K
Sbjct: 625 KADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQKS 684
Query: 1390 NV 1391
+
Sbjct: 685 PI 686
Score = 43.5 bits (101), Expect = 0.001
Identities = 77/362 (21%), Positives = 129/362 (35%), Gaps = 82/362 (22%)
Query: 1153 ETVSNASSSSNPSSPGRIKGRLDSSEMDHSE-NEDYTMSSPLPGKK-------SDKRDDS 1204
+ +S+ + KG +D + E ++D T P +K +K
Sbjct: 112 DIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGK 171
Query: 1205 DLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKP---------------KGSQRS 1249
+ VR EK + KK E+ EK + L +EQK KG ++
Sbjct: 172 EKVR---EKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQE 228
Query: 1250 RKRGHTASESDEQQWPEEKRLKED-----ILENEDEQ-------------NSPPKKGKRG 1291
+ + A + Q+ P + + KED + ++E + + K G+
Sbjct: 229 KVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSP 288
Query: 1292 RPPKPLGGGTPKEEPTMKT-------SKKGSKKKSGPPAPEEEEEEERQ----------S 1334
P PL P E+ + T K+G KKK+ E +++E++ +
Sbjct: 289 AIPPPL----PTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETA 344
Query: 1335 GNTEQK-----SKSKQHRVSRRAQQRAESPESSAIESTQSTP-----QKGRGRPSK---T 1381
+ E+K S++KQ V AQ A+ E P KG+ + K
Sbjct: 345 IDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHV 404
Query: 1382 PSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRS 1441
PKK V KQ K + EE+ G+ + + EE+ TV R
Sbjct: 405 EPAKSPKKEHSVPSDKQVKAKTERAKEEI----GAVSIKKAVPGKKEEKTTKTVEQEIRK 460
Query: 1442 AK 1443
K
Sbjct: 461 EK 462
Score = 42.0 bits (97), Expect = 0.004
Identities = 50/262 (19%), Positives = 99/262 (37%), Gaps = 19/262 (7%)
Query: 1124 KPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSE 1183
K KT K GKQ + K + + PS P + + ++ H +
Sbjct: 207 KAKTAEKSEEKTKKEVKGGKQEKVKQTAAKV---KEVQKTPSKPKEKEDKEKAAVSKHEQ 263
Query: 1184 NEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKP 1243
+ Y + V +L KP P E+ E+K
Sbjct: 264 KDQYAFCRYMI---------DIFVHGDL-KPGQSPAIPPPLPTEQASRPTPASPALEEKE 313
Query: 1244 KGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPK 1303
+++ K+ + ++ E++ ++K KE ++ E ++ + K+G K
Sbjct: 314 GEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKK 373
Query: 1304 EEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAES----P 1359
+E K K +KK + P+ +++E+++ KS K+H V Q +A++
Sbjct: 374 DEK--KEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKE 431
Query: 1360 ESSAIESTQSTPQKGRGRPSKT 1381
E A+ ++ P K + +KT
Sbjct: 432 EIGAVSIKKAVPGKKEEKTTKT 453
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 62.4 bits (150), Expect = 3e-09
Identities = 66/298 (22%), Positives = 110/298 (36%), Gaps = 26/298 (8%)
Query: 1113 PPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQT----KSSRMETVSNASSSSNPSSPG 1168
PP KS T K V S+ + + K + V + +++ P +
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357
Query: 1169 RIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPV------ 1222
+ DSS+ D SE +D S P K+ + +S KP K PV
Sbjct: 358 AAESSSDSSDSDSSE-DDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 1223 ---------TEQEEKLGMDDLTK-LVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKE 1272
+E+E ++ TK +V KPK + K + Q +
Sbjct: 417 LTRKADSSSSEEESSSSEEEKTKKMVATTKPKATA---KAALSLPAKQAPQGSRDSSSDS 473
Query: 1273 DILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEER 1332
D +E+E+ K + +P K GG P + + K K S S EEEEE+
Sbjct: 474 DSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKL 533
Query: 1333 QSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKN 1390
+ + + K + S Q ++ ++S E + +K SK+ S + K+N
Sbjct: 534 KGKGSPRPQAPKANGTSALTAQNGKAAKNS--EEEEEEKKKAAVVVSKSGSLKKRKQN 589
Score = 51.2 bits (121), Expect = 7e-06
Identities = 47/181 (25%), Positives = 81/181 (44%), Gaps = 26/181 (14%)
Query: 1272 EDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEE 1331
ED E E+E PP K K P K +G P + K S+ S ++S ++++EE
Sbjct: 88 EDSSEEEEEVQGPPAK-KAAVPAKRVG--LPPGKAAAKASESSSSEES-----SDDDDEE 139
Query: 1332 RQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTP--------S 1383
Q QK Q + ++ ++A+S +S + S++ P K + +P TP +
Sbjct: 140 DQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQ-KPKITPVTVKAQTKA 198
Query: 1384 PSQPKKNV-RVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSA 1442
P +P + ++ K A++ + SS SS DD +E+ TV ++ A
Sbjct: 199 PPKPARAAPKIANGKAASSSSSSSS--------SSSSDDSEEEKAAATPKKTVPKKQVVA 250
Query: 1443 K 1443
K
Sbjct: 251 K 251
Score = 46.6 bits (109), Expect = 2e-04
Identities = 80/388 (20%), Positives = 139/388 (35%), Gaps = 77/388 (19%)
Query: 1099 TQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSN- 1157
TQ D N S+ + +KS P + N A ++ S+ S E V
Sbjct: 41 TQQDANASSLLDIYSFWLKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGP 100
Query: 1158 -ASSSSNPSS-----PGRIKGRL-DSSEMDHSENED----------------YTMSSPLP 1194
A ++ P+ PG+ + +SS + S ++D ++ P
Sbjct: 101 PAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAP 160
Query: 1195 GKKSDKRDDSDLVRSELEKPRGRKK--TPVTEQEEKLGMDDLTKL---VQEQKPKGSQRS 1249
KK+ D SE E P+ +K TPVT + + + + K S S
Sbjct: 161 PKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSS 220
Query: 1250 RKRGHTASESDEQQ------------------------WPEEKRLK-EDILENEDEQNSP 1284
++ +S+E++ P K ED +E+E+
Sbjct: 221 SSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKK 280
Query: 1285 PKKGKRGR-----------PPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQ 1333
P K K G P K LG PK+ + + S+ S EEE++
Sbjct: 281 PMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPP 340
Query: 1334 SGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQS------TPQKGRGRPS-KTPSP-- 1384
+ K+ +K + A+ ++S +S + E ++ T + +P+ T SP
Sbjct: 341 TKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAV 400
Query: 1385 ---SQPKKNVRVGRSKQAATKENDSSEE 1409
+ PK+ V G+ ++ SSEE
Sbjct: 401 KPAAAPKQPVGGGQKLLTRKADSSSSEE 428
Score = 45.1 bits (105), Expect = 5e-04
Identities = 87/440 (19%), Positives = 160/440 (36%), Gaps = 123/440 (27%)
Query: 1106 SNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPS 1165
S++++ P K TP K A KP +A K + K++ + S++SSSS+ S
Sbjct: 173 SSSEDEPPKNQKPKITPVTVKAQTK--APPKPARAAPKIANGKAASSSSSSSSSSSSDDS 230
Query: 1166 SPGRIKGRLDSSEMDHSENEDYTMSSPLPG------KKSDKRDDSDLVRSELEKPRGRKK 1219
+ + ++ + +P+ K S D S E +KP K
Sbjct: 231 E----EEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKP 286
Query: 1220 TPVTE--------QEEKLGMDDLTKLVQEQKP-KGSQRSRKRGHTASESDEQ-------- 1262
P + ++ LG K V++Q+P + S+ S ++SE +++
Sbjct: 287 GPYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVS 346
Query: 1263 ----QWPEEKRLKEDILENEDEQNSP-------------------------PKKGKRGRP 1293
+ P K+ E ++ D +S P P
Sbjct: 347 KATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAP 406
Query: 1294 PKPLGGG------------------TPKEEPTMK----TSKKGSKK-------KSGPPAP 1324
+P+GGG + +EE T K T K + K K P
Sbjct: 407 KQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGS 466
Query: 1325 EEEEEEERQSGNTEQKSKSKQHRVSRRAQQ----------------RAESPESSAI-EST 1367
+ + S + E++ K+ + V ++ Q+ +AES SS+ +S+
Sbjct: 467 RDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSS 526
Query: 1368 QSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEET 1427
+ +K +G+ S P P PK N A T +N + + +EE
Sbjct: 527 EEEEEKLKGKGS--PRPQAPKAN-----GTSALTAQNGKAAKNS------------EEEE 567
Query: 1428 EEEEVSTVNVRRRSAKRERR 1447
EE++ + V V + + ++R+
Sbjct: 568 EEKKKAAVVVSKSGSLKKRK 587
Score = 37.7 bits (86), Expect = 0.081
Identities = 80/370 (21%), Positives = 137/370 (37%), Gaps = 51/370 (13%)
Query: 1045 ENIKQTKDAQGPDDAKMNEKLYTVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQPDKN 1104
E+ +++ + P + K T A S S + +S +D P++ KN
Sbjct: 328 ESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKP-AGTTKN 386
Query: 1105 FSN-----TKNYLPPEMKSFFTPGKPK-------TTNVLGAVNKPLSSAGKQSQTKSSRM 1152
SN TK+ P +K P +P T + ++ SS+ ++ +TK
Sbjct: 387 SSNKPAVTTKS---PAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVA 443
Query: 1153 ETVSNASSSSNPSSPGRI--KGRLDSS---EMDHSENEDYTMSSPLPGKKSDKRDDSDLV 1207
T A++ + S P + +G DSS + SE E+ S KK K
Sbjct: 444 TTKPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGG--- 500
Query: 1208 RSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSR------------KRGHT 1255
+ KP KK D + ++ K KGS R + + G
Sbjct: 501 -AAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKA 559
Query: 1256 ASESDEQQWPEEKRLKEDILENED-----EQNSPPKKGKRGRPPKPLGGGTPKEEPTMKT 1310
A S+E++ EEK+ ++ +QN K+ + + K + TP T
Sbjct: 560 AKNSEEEE--EEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKK-IKLQTPN---TFPK 613
Query: 1311 SKKGSKKKSGP---PAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIEST 1367
KKG K+ S P EE E + R + N+ + RA Q + + +
Sbjct: 614 RKKGEKRASSPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQVLKFTKGKSFRHE 673
Query: 1368 QSTPQKGRGR 1377
++ ++G R
Sbjct: 674 KTKKKRGSYR 683
Score = 35.8 bits (81), Expect = 0.31
Identities = 30/137 (21%), Positives = 53/137 (38%), Gaps = 7/137 (5%)
Query: 1311 SKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQST 1370
+KK KK S + + EEEE G +K+ RV +A + S + S +S+
Sbjct: 75 AKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVG-LPPGKAAAKASESSSSEESS 133
Query: 1371 PQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEE 1430
K P K + ++ K +DS + SS D+ P+ + +
Sbjct: 134 DDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSD------SSSEDEPPKNQKPKI 187
Query: 1431 EVSTVNVRRRSAKRERR 1447
TV + ++ + R
Sbjct: 188 TPVTVKAQTKAPPKPAR 204
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 62.0 bits (149), Expect = 4e-09
Identities = 71/317 (22%), Positives = 117/317 (36%), Gaps = 29/317 (9%)
Query: 1142 GKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKR 1201
G + + SR + S + S S S R R SS+ HS++ + S KS R
Sbjct: 178 GSRRRRSYSRSRSHSRSRSRSRHSRKSR--SRSGSSKSSHSKSRSRSRSGSRSRSKSRSR 235
Query: 1202 DDSDLVRSELEKPRGRKKTPVTEQEEKLGM------DDLTKLVQEQKPKGSQRSRKRGHT 1255
S RS+ EK R K + G D + +Q G +SR
Sbjct: 236 SQSRS-RSKKEKSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRH 294
Query: 1256 ASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGS 1315
S+S + +E+R++E+ + S K ++ R GG S+ S
Sbjct: 295 KSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGG----------SRSRS 344
Query: 1316 KKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGR 1375
+ +S + + R+ + +S+SK R +R +R SS + + T +
Sbjct: 345 RSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQS 404
Query: 1376 GRPSKTPS------PSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEE 1429
PS++ S S+ + G S+ A T + S S ++P E
Sbjct: 405 RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS---RSNSKSKPNLPSESRSR 461
Query: 1430 EEVSTVNVRRRSAKRER 1446
+ S R RS R R
Sbjct: 462 SK-SASKTRSRSKSRSR 477
Score = 54.7 bits (130), Expect = 6e-07
Identities = 57/289 (19%), Positives = 108/289 (37%), Gaps = 20/289 (6%)
Query: 1117 KSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDS 1176
KS + + ++ + + +K S + +S++K + + S S S S G+ + +
Sbjct: 212 KSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKSKD 271
Query: 1177 SEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVT--EQEEKLGMDDL 1234
+ +N D K RS+ + K+ V+ +EK L
Sbjct: 272 QAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEK----SL 327
Query: 1235 TKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPP 1294
+ + KG RSR R + S+ + KR +E+ ++ + KRG
Sbjct: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRK---GRKRSREESRSRSRSRSKSERSRKRGSKR 384
Query: 1295 KPLGGGTPKEE-----------PTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKS 1343
G + K++ P+ SK+ KS E E E N E +S+S
Sbjct: 385 DSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRS 444
Query: 1344 KQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVR 1392
+ + S+ S + T+S + S++PS S+ + + R
Sbjct: 445 RSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHSR 493
Score = 54.3 bits (129), Expect = 8e-07
Identities = 64/297 (21%), Positives = 118/297 (39%), Gaps = 32/297 (10%)
Query: 1139 SSAGKQSQTKS-SRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKK 1197
S + S+++S SR S + S S+ SS + + R S S++ + S K+
Sbjct: 186 SRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKE 245
Query: 1198 SDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTAS 1257
+ + RS + + EEK+ +D V + K + R + + + S
Sbjct: 246 KSRSPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDN---VGKPKSRSPSRHKSKSKSRS 302
Query: 1258 ESDEQQWPEEKR------LKEDILENEDEQNSPPKKGKRGRP-------PKPLGGGTPKE 1304
S E++ EEKR ++ + S K G R R K G +E
Sbjct: 303 RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSRE 362
Query: 1305 EP---------TMKTSKKGSKK--KSGPPAPEEEEEEERQSGNTEQKSKSKQ--HRVSRR 1351
E + ++ K+GSK+ K+G +++E+ +R + +S SK+ H S
Sbjct: 363 ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSES 422
Query: 1352 AQQRAESPESSAIESTQSTPQKGRGRPSKTPS-PSQPKKNVRVGRSKQAATKENDSS 1407
+Q+ ES + Q T + R P+ PS+ + + ++ +K S
Sbjct: 423 SQREGRG-ESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 60.5 bits (145), Expect = 1e-08
Identities = 73/306 (23%), Positives = 130/306 (42%), Gaps = 28/306 (9%)
Query: 1157 NASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRS---ELEK 1213
N PSSP R +GR D E++ E + + ++ ++ + D R E E+
Sbjct: 634 NRERDQRPSSPIRHQGRND--ELERDERREERRVDRVDDRRDERARERDRERERDRERER 691
Query: 1214 PRGRKKTPVTEQEEKLGMDDLTKLVQE-QKPKGSQRSRKRGHTASESDEQQWPEEKRLKE 1272
R R++ E+E +L + + +E +K + +R R R H E++ EK +
Sbjct: 692 ERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERER 751
Query: 1273 DILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEER 1332
+ E E E+ ++ + + KE + + K + EE E+R
Sbjct: 752 EREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDR 811
Query: 1333 --QSGNTEQKSKSKQHRVSRRA------QQRAESPESSAIESTQSTPQKG-------RGR 1377
+ G+ E+KSK + + ++R SP+S A S +K R +
Sbjct: 812 NPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQ 871
Query: 1378 PSKTPSPSQPKKNVRVGRSKQAATK--ENDSS---EEVDVFQGSSPVDDIPQEETEEEEV 1432
S++ SPS ++ R GR K+ K +SS EE ++ + S VD +E+TE E
Sbjct: 872 ESRSLSPSHLTED-RQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDK-QREQTEILES 929
Query: 1433 STVNVR 1438
S + +
Sbjct: 930 SRMRAQ 935
Score = 46.2 bits (108), Expect = 2e-04
Identities = 69/329 (20%), Positives = 122/329 (37%), Gaps = 14/329 (4%)
Query: 1124 KPKTTNVLGAVNKPLSSAGKQSQTKS-SRMETVSNASSSSNPSSPGRIKGRLDSSEMDHS 1182
KP++T+ G + P+SS S ++S S ++ S + SP + S
Sbjct: 313 KPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSAS 372
Query: 1183 ENEDYTMSSPLPGKKSDKRDDSDL---VRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQ 1239
+++SSP K+S R S + R + E+ +E+ G D K +
Sbjct: 373 PYPSHSLSSP-QRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSR 431
Query: 1240 EQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGG 1299
E++ +S R H + + P + R + D + D + + R
Sbjct: 432 EEREYEQDQSSSRDHR-----DDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYS 486
Query: 1300 GTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESP 1359
KE + S+ S + + E + R+ ++S+S R R E
Sbjct: 487 RDTKESRDPRDSR--STRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIR 544
Query: 1360 ESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSS-EEVDVFQGSSP 1418
S ES GR S+ P P+K R R Q + ++S+ + + S P
Sbjct: 545 NESRNESRSEIRNDRMGR-SRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 603
Query: 1419 VDDIPQEETEEEEVSTVNVRRRSAKRERR 1447
D E ++ + RR +R+RR
Sbjct: 604 ERDRYPERDNRDQARDSSFERRHGERDRR 632
Score = 40.8 bits (94), Expect = 0.010
Identities = 65/346 (18%), Positives = 126/346 (36%), Gaps = 36/346 (10%)
Query: 1123 GKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHS 1182
GK ++N + +P ++ + K ++T ++ SSP R +SS H
Sbjct: 67 GKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVR----KESSRGRHR 122
Query: 1183 ENEDYTMSSPLPGKKSDK-------RDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLT 1235
E ED ++ + ++ RDDSD ++ + + E + + +L
Sbjct: 123 EKEDIKITKERTPESEEENVEWETNRDDSD--NGDINYDYVHELS--LEMKRQKIQRELM 178
Query: 1236 KLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPK 1295
KL QE K + K+ + + P K ++ S PK + +
Sbjct: 179 KLEQENMEKREEIIIKKEVSPEVVRSKLSPSPSLRKSS---KSPKRKSSPKSSSASKKDR 235
Query: 1296 PLGGGTPKEEPTMKTSKKGSKKKSG-------PPAPEE------EEEEERQSGNTEQKSK 1342
+ + SK KK G PP PE+ +E+ + E+K++
Sbjct: 236 KTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTR 295
Query: 1343 SKQHRVS--RRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAA 1400
+ R R +++ + P S++ +P R S + S S +++ R K+
Sbjct: 296 DGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTP 355
Query: 1401 TKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRER 1446
+ + + + +SP P + R RS RE+
Sbjct: 356 SPSYQRTLTPPLRRSASP---YPSHSLSSPQRKQSPPRHRSPMREK 398
Score = 40.8 bits (94), Expect = 0.010
Identities = 62/306 (20%), Positives = 110/306 (35%), Gaps = 60/306 (19%)
Query: 1176 SSEMDHSENEDYTMSSPLPGK-KSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDL 1234
SS DH ++ + P G+ + D RD D R EL R + + M D
Sbjct: 441 SSSRDHRDDRE-----PRDGRDRRDARDTRD--RRELRDSR--------DMRDSREMRDY 485
Query: 1235 TKLVQEQKPKGSQRSRKRGHTASESD-------EQQWPEEKR------LKEDIL------ 1275
++ +E + RS + H + + E +PEE R L+E+
Sbjct: 486 SRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRN 545
Query: 1276 ENEDEQNSPPKKGKRGR-----PPKPLGGGTPKEEPTMKTSKKGS------KKKSGPPA- 1323
E+ +E S + + GR P P G + + S + +S P
Sbjct: 546 ESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPER 605
Query: 1324 ---PEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1380
PE + ++ + + E++ + R +R QR SP +GR +
Sbjct: 606 DRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSP----------IRHQGRNDELE 655
Query: 1381 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1440
+ ++ RV + +E D E D + + +E +E E+ R R
Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARER 715
Query: 1441 SAKRER 1446
+RE+
Sbjct: 716 EREREK 721
Score = 33.5 bits (75), Expect = 1.5
Identities = 50/255 (19%), Positives = 97/255 (38%), Gaps = 26/255 (10%)
Query: 1197 KSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTA 1256
K RDD R E+ + R + + +K + E P Q ++R +
Sbjct: 793 KDKGRDDRREKREEIREDRNPRDGHDERKSKK-------RYRNEGSPSPRQSPKRRREHS 845
Query: 1257 SESDEQQWPEEK----RLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSK 1312
+SD ++K RL ++ ++ ++ P R G KEE K
Sbjct: 846 PDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQ------GRWKEEDRKPERK 899
Query: 1313 KGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSR-RAQQRAESPESSAIESTQSTP 1371
+ S++ EE+E +E+ S +Q+ +++ SR RAQ +S E++
Sbjct: 900 ESSRRY------EEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953
Query: 1372 QKGRGRPSKTPSPSQPKKNVRVG--RSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEE 1429
+ + + P + KK VG R T E+ Q ++ ++ +
Sbjct: 954 DENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGD 1013
Query: 1430 EEVSTVNVRRRSAKR 1444
++S ++S K+
Sbjct: 1014 SDISDEEAAQQSKKK 1028
Score = 32.7 bits (73), Expect = 2.6
Identities = 42/205 (20%), Positives = 81/205 (39%), Gaps = 23/205 (11%)
Query: 1196 KKSDKR-DDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGH 1254
K+S +R ++ +L + R++T + E D + E + R
Sbjct: 899 KESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSD---RAHDE 955
Query: 1255 TASESDEQQWPEEKRLKEDI--------LENEDEQNSPPKKGKRGRP-PKPLGGGTPKEE 1305
++ Q+ P +K+ ++D+ +ED Q PKKG++ + K +
Sbjct: 956 NKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSD 1015
Query: 1306 PTMKTSKKGSKKKSGPPAPEEEEEEE------RQSGNTEQKSKSKQHRVSRRAQQRAESP 1359
+ + + + SKKK GP P +EE ++G E K + S + + + P
Sbjct: 1016 ISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDE--DVP 1073
Query: 1360 ESSAIESTQSTPQKGRGRPSKTPSP 1384
+ + + + T P TPSP
Sbjct: 1074 DRTEVTEAEHTAT--ATTPGSTPSP 1096
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 [Homo
sapiens]
Length = 916
Score = 60.1 bits (144), Expect = 2e-08
Identities = 74/325 (22%), Positives = 132/325 (40%), Gaps = 36/325 (11%)
Query: 1143 KQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRD 1202
K+ + KS + T + + P + K + S ++ SP+P +++
Sbjct: 586 KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK------SPVPKSPVEEKG 639
Query: 1203 DSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD-- 1260
S + +S +E+ +G+ P + EEK G ++K E+K K S+++
Sbjct: 640 KSPVPKSPVEE-KGKSPVPKSPVEEK-GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG 697
Query: 1261 --EQQWPEEKRLKEDILEN--EDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTS----- 1311
EQ+ EEK +KE E E ++ P ++ + P+ E T+ S
Sbjct: 698 KGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL 757
Query: 1312 KKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTP 1371
+K +K++ P E+E+E+ G +E++ K + SR+ E Q T
Sbjct: 758 EKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 817
Query: 1372 QKGRGRPSKTP--------SPSQPKKNVRVGRSKQAATK--ENDSSEEVD-----VFQGS 1416
+KG GR + SP+ KK K TK E +SE D + +
Sbjct: 818 EKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSV 877
Query: 1417 SPVDDIPQEET--EEEEVSTVNVRR 1439
+ + + E EE+ VST V +
Sbjct: 878 TVTQKVEEHEETFEEKLVSTKKVEK 902
Score = 50.8 bits (120), Expect = 9e-06
Identities = 55/269 (20%), Positives = 109/269 (40%), Gaps = 21/269 (7%)
Query: 1178 EMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKL 1237
++ H E+ + + +KS+ + + EL +K E++E
Sbjct: 447 KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE---------- 496
Query: 1238 VQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPL 1297
+E + + + + K+ + + E + E ++ +E+ E E+E++ K +
Sbjct: 497 -EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE----- 550
Query: 1298 GGGTPKEEPTMKTSKKGSKKKSGPPAPEE-EEEEERQSGNTEQKSKSKQHRVSRRAQQRA 1356
GG+ KE + K ++G +++ A E EE E ++ E+KS+ + A +
Sbjct: 551 -GGSEKEGSSEK--EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 607
Query: 1357 ESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGS 1416
E PE A +P + +G+ SP + K V +S ++ + +G
Sbjct: 608 EKPE-KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 666
Query: 1417 SPVDDIPQEETEEEEVSTVNVRRRSAKRE 1445
SPV P EE + V V +K E
Sbjct: 667 SPVSKSPVEEKAKSPVPKSPVEEAKSKAE 695
Score = 46.2 bits (108), Expect = 2e-04
Identities = 65/335 (19%), Positives = 127/335 (37%), Gaps = 37/335 (11%)
Query: 1124 KPKTTNVLGAVNKPLSSAGKQSQTKSSR-METVSNASSSSNPSSPGRIKGRLDSSEMDHS 1182
K + L A+ + L+ + K+ + +++ E A + +K + +
Sbjct: 466 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 525
Query: 1183 ENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQK 1242
E E+ G++ ++ +D +S+ + G +K +E+EE + T E +
Sbjct: 526 EKEEEE------GQEEEEEEDEG-AKSDQAEEGGSEKEGSSEKEEGEQEEGET----EAE 574
Query: 1243 PKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSP--------------PK-- 1286
+G + K E E+ +E+ + + +E ++ SP PK
Sbjct: 575 AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP 634
Query: 1287 ---KGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKS 1343
KGK P P+ P +KG S P E+ + +S E KSK+
Sbjct: 635 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKA 694
Query: 1344 KQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKN-----VRVGRSKQ 1398
+ + ++ ++ E E+ E + +K + P K + S K+ V + +S +
Sbjct: 695 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 754
Query: 1399 AATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVS 1433
E ++ EE Q + E EEE S
Sbjct: 755 VHL-EKETKEEGKPLQQEKEKEKAGGEGGSEEEGS 788
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 [Homo
sapiens]
Length = 540
Score = 60.1 bits (144), Expect = 2e-08
Identities = 74/325 (22%), Positives = 132/325 (40%), Gaps = 36/325 (11%)
Query: 1143 KQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRD 1202
K+ + KS + T + + P + K + S ++ SP+P +++
Sbjct: 210 KKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK------SPVPKSPVEEKG 263
Query: 1203 DSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESD-- 1260
S + +S +E+ +G+ P + EEK G ++K E+K K S+++
Sbjct: 264 KSPVPKSPVEE-KGKSPVPKSPVEEK-GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG 321
Query: 1261 --EQQWPEEKRLKEDILEN--EDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTS----- 1311
EQ+ EEK +KE E E ++ P ++ + P+ E T+ S
Sbjct: 322 KGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL 381
Query: 1312 KKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTP 1371
+K +K++ P E+E+E+ G +E++ K + SR+ E Q T
Sbjct: 382 EKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETK 441
Query: 1372 QKGRGRPSKTP--------SPSQPKKNVRVGRSKQAATK--ENDSSEEVD-----VFQGS 1416
+KG GR + SP+ KK K TK E +SE D + +
Sbjct: 442 EKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGGDGATKYITKSV 501
Query: 1417 SPVDDIPQEET--EEEEVSTVNVRR 1439
+ + + E EE+ VST V +
Sbjct: 502 TVTQKVEEHEETFEEKLVSTKKVEK 526
Score = 50.8 bits (120), Expect = 9e-06
Identities = 55/269 (20%), Positives = 109/269 (40%), Gaps = 21/269 (7%)
Query: 1178 EMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKL 1237
++ H E+ + + +KS+ + + EL +K E++E
Sbjct: 71 KVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKE---------- 120
Query: 1238 VQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPL 1297
+E + + + + K+ + + E + E ++ +E+ E E+E++ K +
Sbjct: 121 -EEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEE----- 174
Query: 1298 GGGTPKEEPTMKTSKKGSKKKSGPPAPEE-EEEEERQSGNTEQKSKSKQHRVSRRAQQRA 1356
GG+ KE + K ++G +++ A E EE E ++ E+KS+ + A +
Sbjct: 175 -GGSEKEGSSEK--EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 231
Query: 1357 ESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGS 1416
E PE A +P + +G+ SP + K V +S ++ + +G
Sbjct: 232 EKPE-KAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 290
Query: 1417 SPVDDIPQEETEEEEVSTVNVRRRSAKRE 1445
SPV P EE + V V +K E
Sbjct: 291 SPVSKSPVEEKAKSPVPKSPVEEAKSKAE 319
Score = 46.2 bits (108), Expect = 2e-04
Identities = 65/335 (19%), Positives = 127/335 (37%), Gaps = 37/335 (11%)
Query: 1124 KPKTTNVLGAVNKPLSSAGKQSQTKSSR-METVSNASSSSNPSSPGRIKGRLDSSEMDHS 1182
K + L A+ + L+ + K+ + +++ E A + +K + +
Sbjct: 90 KSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEG 149
Query: 1183 ENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQK 1242
E E+ G++ ++ +D +S+ + G +K +E+EE + T E +
Sbjct: 150 EKEEEE------GQEEEEEEDEG-AKSDQAEEGGSEKEGSSEKEEGEQEEGET----EAE 198
Query: 1243 PKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSP--------------PK-- 1286
+G + K E E+ +E+ + + +E ++ SP PK
Sbjct: 199 AEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSP 258
Query: 1287 ---KGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKS 1343
KGK P P+ P +KG S P E+ + +S E KSK+
Sbjct: 259 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKA 318
Query: 1344 KQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKN-----VRVGRSKQ 1398
+ + ++ ++ E E+ E + +K + P K + S K+ V + +S +
Sbjct: 319 EVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVK 378
Query: 1399 AATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVS 1433
E ++ EE Q + E EEE S
Sbjct: 379 VHL-EKETKEEGKPLQQEKEKEKAGGEGGSEEEGS 412
>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
protein [Homo sapiens]
Length = 1463
Score = 59.7 bits (143), Expect = 2e-08
Identities = 83/344 (24%), Positives = 134/344 (38%), Gaps = 47/344 (13%)
Query: 1086 ESPKDPVLPARFFTQPDKNFSNTKN-YLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQ 1144
E P+ LP Q K+FS N +P E SF + + V +VN L +
Sbjct: 690 EHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCS--DQNESEVEPSVNADLKQMNEN 747
Query: 1145 SQTKSS------------RMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSP 1192
S T S ++ETVS S S + K R S HS + ++ +
Sbjct: 748 SVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRF-HSPSTTWSPNKD 806
Query: 1193 LPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKR 1252
P +K KR S R E K + ++P + E G K + Q PK +R+R
Sbjct: 807 TPQEK--KRPQSPSPRRETGKESRKSQSPSPKNESARG----RKKSRSQSPK-KDIARER 859
Query: 1253 GHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSK 1312
+ S S ++ E R E + SP ++ R + +P +K S
Sbjct: 860 RQSQSRSPKRDTTRESRRSESL--------SPRRETSR---------ENKRSQPRVKDSS 902
Query: 1313 KGSKKKSGPPAPEEEEEEER--QSGNTEQKSKSKQH-RVSRRAQQRAESPESSAIESTQS 1369
G K +S E + + +R + T + S+S+ H R R + +++S I+
Sbjct: 903 PGEKSRSQSRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSKSSSFGRIDRDSY 962
Query: 1370 TPQ-KGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDV 1412
+P+ KGR P+ N R ++ EN E+ D+
Sbjct: 963 SPRWKGRW---ANDGWRCPRGNDRYRKNDPEKQNENTRKEKNDI 1003
Score = 38.9 bits (89), Expect = 0.036
Identities = 57/271 (21%), Positives = 111/271 (40%), Gaps = 38/271 (14%)
Query: 1135 NKPLSSAGKQSQTKSSRMETVSNASSSSN----PSSPGRIKGRLDSSEMDHSENEDYTM- 1189
N+ L+ + ++ + +E + S N P + SE++ S N D
Sbjct: 685 NESLTEHPRSTELPKTHIEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVNADLKQM 744
Query: 1190 -SSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQR 1248
+ + + SDL ++E ++P D + K +KP+ ++R
Sbjct: 745 NENSVTHCSENNMPSSDLADEKVETVSQPSESP---------KDTIDKT---KKPR-TRR 791
Query: 1249 SRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTM 1308
SR + + S + P+EK+ + SP + + G+ + +PK E
Sbjct: 792 SRFHSPSTTWSPNKDTPQEKKRPQ----------SPSPRRETGKESRKSQSPSPKNE--- 838
Query: 1309 KTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQ 1368
S +G KK ++ E RQS + K + R SRR++ + E+S E+ +
Sbjct: 839 --SARGRKKSRSQSPKKDIARERRQSQSRSPKRDTT--RESRRSESLSPRRETSR-ENKR 893
Query: 1369 STPQKGRGRP-SKTPSPSQPKKNVRVGRSKQ 1398
S P+ P K+ S S+ +++ R G+ ++
Sbjct: 894 SQPRVKDSSPGEKSRSQSRERESDRDGQRRE 924
Score = 35.8 bits (81), Expect = 0.31
Identities = 35/198 (17%), Positives = 69/198 (34%), Gaps = 17/198 (8%)
Query: 1254 HTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKK 1313
++ + E P E + SP + + P+ T +K
Sbjct: 747 NSVTHCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHSPSTTWSPNKD 806
Query: 1314 GSKKKSGPPAPEEEEE---EERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQST 1370
++K P +P E E R+S + K++S + R R+Q + +S +
Sbjct: 807 TPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDIARERRQSQSRS 866
Query: 1371 PQKGRGRPSKTPSPSQPKKNV-RVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEE 1429
P++ R S+ P++ R + Q K++ E+ + ++ E
Sbjct: 867 PKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEK-------------SRSQSRE 913
Query: 1430 EEVSTVNVRRRSAKRERR 1447
E RR +R R+
Sbjct: 914 RESDRDGQRRERERRTRK 931
Score = 32.3 bits (72), Expect = 3.4
Identities = 33/155 (21%), Positives = 66/155 (42%), Gaps = 17/155 (10%)
Query: 1300 GTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESP 1359
G K++ + ++ +GS++K P R + NT ++ S+ R ++P
Sbjct: 295 GEEKKQTSGTSNTRGSRRKPAMTTPTR-----RSTRNTRAETASQSQRSPISDNSGCDAP 349
Query: 1360 ESS----AIESTQSTPQKGRGRPSKTP-----SPSQPKKNVRVGRSKQAATKENDSSEEV 1410
+S ++ S+ + ++ R P + P KK +R + + NDS +E
Sbjct: 350 GNSNPSLSVPSSAESEKQTRQAPKRKSVRRGRKPPLLKKKLRSSVAAPEKSSSNDSVDEE 409
Query: 1411 DVFQGSSPV-DDIPQEETEEEEVSTV--NVRRRSA 1442
+SPV + Q + + + TV +V +SA
Sbjct: 410 TAESDTSPVLEKEHQPDVDSSNICTVQTHVENQSA 444
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 59.7 bits (143), Expect = 2e-08
Identities = 72/304 (23%), Positives = 127/304 (41%), Gaps = 47/304 (15%)
Query: 1170 IKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDL----------VRSELEKPRGRKK 1219
+K +++ SE+ E S L +K K+DDS+ V+S EKP R+K
Sbjct: 676 VKRQVERSEI--CTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPE-REK 732
Query: 1220 TPVTEQEEKLGMDDLTK--LVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILEN 1277
TP E+KL + K + + + S ++G E+ ++Q + K +D E
Sbjct: 733 TP---SEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTER 789
Query: 1278 EDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNT 1337
+ + + K G+ KP+ K + ++ +++ + E + R S +
Sbjct: 790 KSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSK 849
Query: 1338 EQKSK--SKQHRVSRRAQQRAESPESSAIEST--------QSTPQKGRGRPS-------- 1379
QK SKQH ++ + + + S + ++ST + K + R
Sbjct: 850 IQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLV 909
Query: 1380 -KTPSPSQPKK------NVRVGRSKQAAT----KENDSSEEVDVFQGSSPVDDIPQEETE 1428
K+ S +Q K+ ++ G +KQA T KE ++ E Q S V+D P EET
Sbjct: 910 LKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETG 969
Query: 1429 EEEV 1432
E V
Sbjct: 970 VEPV 973
Score = 52.4 bits (124), Expect = 3e-06
Identities = 60/228 (26%), Positives = 93/228 (40%), Gaps = 35/228 (15%)
Query: 1183 ENEDYTMSSPLPGKKSDKRDDSDLVRSELEKP------RGRKKTPVTEQEEKLGMDDLTK 1236
E +D SS G+K ++ DD + E ++P RGR + E K+ D T
Sbjct: 2837 EEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTD 2896
Query: 1237 ---LVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENED-EQNSPPKKGKRGR 1292
+ EQ P S+ ++DE E L+E + N+D E+ +RGR
Sbjct: 2897 TGIVTVEQSPSSSKLK------VMQTDESN-KETANLQERSISNDDGEEKIVTSVRRRGR 2949
Query: 1293 PPK---PLGGGTPKEEPTMKTSKKGS-----KKKSGPPAPEEEEEEERQSGNTEQKSKSK 1344
PK + EP K K S KK+ EEEEEE+ SG T + +
Sbjct: 2950 KPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRST--- 3006
Query: 1345 QHRVSRRAQQRAESPESSAIESTQSTPQKG---RGRPSKTPSPSQPKK 1389
+R QR+++ S +I+ + G RG+ +P + K
Sbjct: 3007 ----TRSEAQRSKTQLSPSIKRKREVSPPGARTRGQQRVEEAPVKKAK 3050
Score = 49.3 bits (116), Expect = 3e-05
Identities = 67/317 (21%), Positives = 129/317 (40%), Gaps = 49/317 (15%)
Query: 1139 SSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKS 1198
S + + + S R + S S + P ++ + M + + + +SS +
Sbjct: 2730 SESYNKGEISSGRKDNAEAISGHSVEADPKEVEE--EERHMPKRKRKQHYLSS-----ED 2782
Query: 1199 DKRDDSDLVRSELEKPRGRKKTPVTE-----QEEKLGMDDLTKLVQEQKPKGSQRSRKRG 1253
+ D+ D++ S +E +++ P TE +E +++L K E S+ ++
Sbjct: 2783 EPDDNPDVLDSRIET--AQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKD 2840
Query: 1254 HTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPK-PLGGGTPKEEPTMKTSK 1312
+S + PE+ +D +++++E K KRGRP K P+ E T+K K
Sbjct: 2841 EYSSSETTGEKPEQN--DDDTIKSQEEDQPIIIKRKRGRPRKYPV-------ETTLKM-K 2890
Query: 1313 KGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQ 1372
SK +G E+ S + + ++ + Q+R+ S + + S +
Sbjct: 2891 DDSKTDTGIVTVEQSPS----SSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRR 2946
Query: 1373 KGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDD-----IPQEET 1427
+GR +PK+++ V +++ E + V S PV+D +EE
Sbjct: 2947 RGR----------KPKRSLTVSDDAESSEPERKRQKSV-----SDPVEDKKEQESDEEEE 2991
Query: 1428 EEEEVSTVNVRRRSAKR 1444
EEEE RS R
Sbjct: 2992 EEEEDEPSGATTRSTTR 3008
Score = 43.1 bits (100), Expect = 0.002
Identities = 82/460 (17%), Positives = 172/460 (37%), Gaps = 32/460 (6%)
Query: 1007 KVQDIEQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLY 1066
K +D +++KD K+ +E L +E NS+ K VE K+ D + ++ +
Sbjct: 351 KSEDTQKVKDEKQAKEKEVESLKLPSEKNSNK--AKTVEGTKE-------DFSLIDSDVD 401
Query: 1067 TVCDVAMNIIMSKSTTYSLESPKDPVLPARFFTQ----PDKNFSNTKNYLPPEMKSFFTP 1122
+ D+ ++ + + + E ++ V+ + + D N +N + S +
Sbjct: 402 GLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQ-TSDSSE 460
Query: 1123 GKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHS 1182
GK K+ V+KP + K + S + ++ +++ +++
Sbjct: 461 GKTKSVR-HAYVHKPYLYS-KYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEK 518
Query: 1183 ENE--DYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQE 1240
+ + T SS G+ D + LE R K + E++ L+K ++
Sbjct: 519 RKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKK 578
Query: 1241 QKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGG 1300
+ S+K+ +S E E KE I + E K + +P + L
Sbjct: 579 DSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKI-SSSKELKHVHAKSEPSKPARRLSES 637
Query: 1301 ---TPKEEPTMKTSKKGSKKKSGPPAPEEEEEE----------ERQSGNTEQKSKSKQHR 1347
+ + K ++ ++ S P E +EE ER TE+ K K
Sbjct: 638 LHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTL 697
Query: 1348 VSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSS 1407
+ + ++ +S + + + +P + +PS+ K +V+ K D +
Sbjct: 698 KNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDET 757
Query: 1408 EEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRERR 1447
E +G ++I ++ + + S R+S R R
Sbjct: 758 ELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNER 797
Score = 38.9 bits (89), Expect = 0.036
Identities = 56/295 (18%), Positives = 121/295 (41%), Gaps = 22/295 (7%)
Query: 1143 KQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDS-SEMDHSENEDYTMSSPLPGKKSDKR 1201
K+ T+ + E + P ++ L++ S HS +D + + LP K +
Sbjct: 943 KEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYK 1002
Query: 1202 DDSDLVRSELEK--PRGRKKTPVTEQEEKLGMDDLTKL-VQEQKPKGSQRSRKRGHTA-- 1256
D D + LE+ G K + + + D K ++ K S + RG+++
Sbjct: 1003 SDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLM 1062
Query: 1257 SESDEQQWPEEKR--LKEDILENEDE---QNSPPKKGKRGRPPKPLGGGT--PKEEPTMK 1309
+ ++ E +R L +++ + E++ G + PK G T P++EP
Sbjct: 1063 EKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEI 1122
Query: 1310 TSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQS 1369
S+ G + E + ++ ++ N++Q S+ + A + + + +S +
Sbjct: 1123 DSEPGVEN-----VFEVSKTQDNRNNNSQQDIDSENMKQKTSATVQKDELRTCTADSKAT 1177
Query: 1370 TPQKGRGRPSKTPSPSQPKKNVRVGRSK----QAATKENDSSEEVDVFQGSSPVD 1420
P GR + S S+ + R +K Q+A + + E+ + +G++ V+
Sbjct: 1178 APAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVN 1232
Score = 38.1 bits (87), Expect = 0.062
Identities = 46/243 (18%), Positives = 96/243 (39%), Gaps = 12/243 (4%)
Query: 1207 VRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQ---KPKG-SQRSRKRGHTASESDEQ 1262
VR E K R T+ E K +K+ ++ K G + + R ++ + D
Sbjct: 820 VRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMD 879
Query: 1263 QWPEEKRLK-EDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTS-KKGSKKKSG 1320
+ LK E+++ E + + K K G K+ ++T ++G+ K++
Sbjct: 880 STNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQG--KQVKVVETELQEGATKQAT 937
Query: 1321 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSK 1380
P P++E+ E ++KSK + + SS+ ST QK +K
Sbjct: 938 TPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHST----QKDSSHRAK 993
Query: 1381 TPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRR 1440
P + K+ + S + K +D + + S + + ++++++ V+
Sbjct: 994 LPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHE 1053
Query: 1441 SAK 1443
A+
Sbjct: 1054 KAR 1056
Score = 37.4 bits (85), Expect = 0.11
Identities = 42/198 (21%), Positives = 75/198 (37%), Gaps = 35/198 (17%)
Query: 1258 ESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKK 1317
E +E+ P+ KR K+ L +EDE P + P + S+ + +
Sbjct: 2762 EEEERHMPKRKR-KQHYLSSEDE---------------------PDDNPDVLDSRIETAQ 2799
Query: 1318 KSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGR 1377
+ P E + +E S + E+ K+ S ++ E E S+ E+T P++
Sbjct: 2800 RQCPET-EPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDD 2858
Query: 1378 PSKTPSPSQP----KKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQE------ET 1427
K+ QP +K R + T + + D G V+ P +T
Sbjct: 2859 TIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDT--GIVTVEQSPSSSKLKVMQT 2916
Query: 1428 EEEEVSTVNVRRRSAKRE 1445
+E T N++ RS +
Sbjct: 2917 DESNKETANLQERSISND 2934
Score = 32.7 bits (73), Expect = 2.6
Identities = 33/147 (22%), Positives = 55/147 (37%), Gaps = 17/147 (11%)
Query: 1128 TNVLGAVNKPLSSAGKQSQTKSSRMET-------VSNASSSSNPSSPGRIKGRL------ 1174
T ++ P SS K QT S ET +SN + R +GR
Sbjct: 2897 TGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLT 2956
Query: 1175 --DSSEMDHSENE-DYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGM 1231
D +E E + ++S P+ KK + D+ + E ++P G T E +
Sbjct: 2957 VSDDAESSEPERKRQKSVSDPVEDKKEQESDEEE-EEEEEDEPSGATTRSTTRSEAQRSK 3015
Query: 1232 DDLTKLVQEQKPKGSQRSRKRGHTASE 1258
L+ ++ ++ +R RG E
Sbjct: 3016 TQLSPSIKRKREVSPPGARTRGQQRVE 3042
Score = 32.3 bits (72), Expect = 3.4
Identities = 32/157 (20%), Positives = 59/157 (37%), Gaps = 28/157 (17%)
Query: 1304 EEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSA 1363
E KTS++ SKK P + ++ER S + K KS + +S E S
Sbjct: 223 ETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSD 282
Query: 1364 IE-----------------------STQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAA 1400
+ +S+ QK + P +K R K+
Sbjct: 283 LPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKT 342
Query: 1401 TKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNV 1437
K+ D S++ + + V D +++ +E+EV ++ +
Sbjct: 343 EKKFDHSKK---SEDTQKVKD--EKQAKEKEVESLKL 374
>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
Length = 330
Score = 59.7 bits (143), Expect = 2e-08
Identities = 46/208 (22%), Positives = 91/208 (43%), Gaps = 7/208 (3%)
Query: 1200 KRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASES 1259
+R++SD E GRKK + + +G + K V++++ +G + + +
Sbjct: 116 EREESDGEYDEF----GRKKKKY--RGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKL 169
Query: 1260 DEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKS 1319
DE + ++ L + L+ +E++S KK R K + + S S+ +S
Sbjct: 170 DEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS 229
Query: 1320 GPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPS 1379
+ + R S +S+ + R S R+ + + SP + S+ S+P++ R R S
Sbjct: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKR-S 288
Query: 1380 KTPSPSQPKKNVRVGRSKQAATKENDSS 1407
++ S S + R RS+ + SS
Sbjct: 289 RSRSSSSGDRKKRRTRSRSPERRHRSSS 316
Score = 36.2 bits (82), Expect = 0.24
Identities = 27/122 (22%), Positives = 49/122 (40%), Gaps = 1/122 (0%)
Query: 1325 EEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSP 1384
+ EEE+ + ++S+SK R+ R+ SP SS S +S + S++ S
Sbjct: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS-RSRSRSSSSSQSRSRSS 244
Query: 1385 SQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKR 1444
S+ + R +S+ ++ SS SS + S+ R++ R
Sbjct: 245 SRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTR 304
Query: 1445 ER 1446
R
Sbjct: 305 SR 306
Score = 35.4 bits (80), Expect = 0.40
Identities = 35/170 (20%), Positives = 64/170 (37%), Gaps = 5/170 (2%)
Query: 1243 PKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTP 1302
PK ++ + G+ ++ + +R + D +E + +GK P L
Sbjct: 91 PKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVED 150
Query: 1303 KEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGN-----TEQKSKSKQHRVSRRAQQRAE 1357
KE + + K E+E++ + N E +K K +R SR + +
Sbjct: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
Query: 1358 SPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSS 1407
S SS S S+ + R R + S ++ RS+ +K SS
Sbjct: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
Score = 32.7 bits (73), Expect = 2.6
Identities = 38/175 (21%), Positives = 59/175 (33%), Gaps = 26/175 (14%)
Query: 1174 LDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDD 1233
L +D SE ED KKS++R S RS + R +P + +
Sbjct: 180 LSKYNLDASEEEDSNK------KKSNRRSRSKS-RSSHSRSSSRSSSPSSSRSRSRSRSR 232
Query: 1234 LTKLVQEQKPKGS-QRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGR 1292
+ Q + S +RSR RG + S K +SP + KR R
Sbjct: 233 SSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSY---SSSSSSPERNRKRSR 289
Query: 1293 PPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHR 1347
++S G +KK + E SG++ S+S +
Sbjct: 290 S---------------RSSSSGDRKKRRTRSRSPERRHRSSSGSSHSGSRSSSKK 329
>gi|190014588 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 59.3 bits (142), Expect = 3e-08
Identities = 57/261 (21%), Positives = 117/261 (44%), Gaps = 42/261 (16%)
Query: 1210 ELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKR 1269
E+E+ T+ EEK +D+TK V PK ++R RKR ++++Q EE
Sbjct: 109 EVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKR-----KAEKQVETEEAG 163
Query: 1270 LKEDILENEDEQNSPPKKGKRGRP-------PKPLGGGTPKEEPTM----------KTSK 1312
+ + + + SP KRGRP PKP G ++P K+ K
Sbjct: 164 VVTTATASVNLKVSP----KRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKK 219
Query: 1313 KGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQ 1372
KG ++K P+++EE +++ ++ K+ + + + + ++ + + ST + +
Sbjct: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGK--KEVESKRKNLAKTGVTSTSDSEE 277
Query: 1373 KG------RGRPSKTPSPSQPKKNVRVGR-SKQAATKENDSSEEVDVFQGSSPVDDIPQE 1425
+G + R + ++N+ G+ K+AA ++ E+++ Q + ++
Sbjct: 278 EGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQN-------KD 330
Query: 1426 ETEEEEVSTVNVRRRSAKRER 1446
E ++ EV V +R ++ R
Sbjct: 331 EGKKPEVKKVEKKRETSMDSR 351
Score = 50.4 bits (119), Expect = 1e-05
Identities = 80/375 (21%), Positives = 143/375 (38%), Gaps = 35/375 (9%)
Query: 1088 PKDPVLPARFFTQPDKNFSNTKNYLP-PEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQ 1146
P LP FF + F K+ P E K + GKP N N+ L +
Sbjct: 35 PPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKY--GKP---NKRKGFNEGLWEIDNNPK 89
Query: 1147 TKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSE---NEDYTMSSPLPGKKSDKRDD 1203
K S + + S++S+ + + + DH E NED T + + K+ +R
Sbjct: 90 VKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGR 149
Query: 1204 SDLVRSELEKPRGRKKTPVT-----EQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASE 1258
++E T T + K G T+ V+ KP+G + K+ SE
Sbjct: 150 KRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATE-VKIPKPRGRPKMVKQ-PCPSE 207
Query: 1259 SDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKK--GSK 1316
SD ++ + K + E + PKK + G+ + P++EP K KK SK
Sbjct: 208 SDIITEEDKSKKKG---QEEKQPKKQPKKDEEGQKEE----DKPRKEPDKKEGKKEVESK 260
Query: 1317 KKS-----GPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTP 1371
+K+ + EEE + Q G ++K RR + + + +A +
Sbjct: 261 RKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEE 320
Query: 1372 QKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEE-- 1429
Q + +K K V R ++ E+ + S +D++ E
Sbjct: 321 QMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEI---KNSLKIDNLDVNRCIEAL 377
Query: 1430 EEVSTVNVRRRSAKR 1444
+E++++ V + A++
Sbjct: 378 DELASLQVTMQQAQK 392
>gi|19923653 PC4 and SFRS1 interacting protein 1 isoform 2 [Homo
sapiens]
Length = 530
Score = 59.3 bits (142), Expect = 3e-08
Identities = 57/261 (21%), Positives = 117/261 (44%), Gaps = 42/261 (16%)
Query: 1210 ELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKR 1269
E+E+ T+ EEK +D+TK V PK ++R RKR ++++Q EE
Sbjct: 109 EVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKR-----KAEKQVETEEAG 163
Query: 1270 LKEDILENEDEQNSPPKKGKRGRP-------PKPLGGGTPKEEPTM----------KTSK 1312
+ + + + SP KRGRP PKP G ++P K+ K
Sbjct: 164 VVTTATASVNLKVSP----KRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKK 219
Query: 1313 KGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQ 1372
KG ++K P+++EE +++ ++ K+ + + + + ++ + + ST + +
Sbjct: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGK--KEVESKRKNLAKTGVTSTSDSEE 277
Query: 1373 KG------RGRPSKTPSPSQPKKNVRVGR-SKQAATKENDSSEEVDVFQGSSPVDDIPQE 1425
+G + R + ++N+ G+ K+AA ++ E+++ Q + ++
Sbjct: 278 EGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEEQMETEQQN-------KD 330
Query: 1426 ETEEEEVSTVNVRRRSAKRER 1446
E ++ EV V +R ++ R
Sbjct: 331 EGKKPEVKKVEKKRETSMDSR 351
Score = 50.4 bits (119), Expect = 1e-05
Identities = 80/375 (21%), Positives = 143/375 (38%), Gaps = 35/375 (9%)
Query: 1088 PKDPVLPARFFTQPDKNFSNTKNYLP-PEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQ 1146
P LP FF + F K+ P E K + GKP N N+ L +
Sbjct: 35 PPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKY--GKP---NKRKGFNEGLWEIDNNPK 89
Query: 1147 TKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSE---NEDYTMSSPLPGKKSDKRDD 1203
K S + + S++S+ + + + DH E NED T + + K+ +R
Sbjct: 90 VKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGR 149
Query: 1204 SDLVRSELEKPRGRKKTPVT-----EQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASE 1258
++E T T + K G T+ V+ KP+G + K+ SE
Sbjct: 150 KRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATE-VKIPKPRGRPKMVKQ-PCPSE 207
Query: 1259 SDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKK--GSK 1316
SD ++ + K + E + PKK + G+ + P++EP K KK SK
Sbjct: 208 SDIITEEDKSKKKG---QEEKQPKKQPKKDEEGQKEE----DKPRKEPDKKEGKKEVESK 260
Query: 1317 KKS-----GPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTP 1371
+K+ + EEE + Q G ++K RR + + + +A +
Sbjct: 261 RKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAADRKRKQEE 320
Query: 1372 QKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEE-- 1429
Q + +K K V R ++ E+ + S +D++ E
Sbjct: 321 QMETEQQNKDEGKKPEVKKVEKKRETSMDSRLQRIHAEI---KNSLKIDNLDVNRCIEAL 377
Query: 1430 EEVSTVNVRRRSAKR 1444
+E++++ V + A++
Sbjct: 378 DELASLQVTMQQAQK 392
>gi|4557509 cylicin 2 [Homo sapiens]
Length = 348
Score = 58.2 bits (139), Expect = 6e-08
Identities = 44/212 (20%), Positives = 91/212 (42%), Gaps = 8/212 (3%)
Query: 1244 KGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPK 1303
KG ++ ++ T SES+ +Q ++ + +DI + ++E+ K K+G+ G +
Sbjct: 117 KGEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSAT 176
Query: 1304 EEPTMK-TSKKGSK--KKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPE 1360
E K +KK +K KK + E E + G TE+ SK + + E
Sbjct: 177 ESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQA 236
Query: 1361 SSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGS---- 1416
A E +K + ++ + K ++ G+ + DS + DV + S
Sbjct: 237 VKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESKKDA 296
Query: 1417 -SPVDDIPQEETEEEEVSTVNVRRRSAKRERR 1447
+ +++TE+E + +++AK++ +
Sbjct: 297 TKDAKKVAKKDTEKESADSKKDAKKNAKKDAK 328
Score = 51.2 bits (121), Expect = 7e-06
Identities = 53/234 (22%), Positives = 98/234 (41%), Gaps = 28/234 (11%)
Query: 1195 GKKS-DKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRG 1253
GKK DK D SE E +G+K + + EK G ++ ++ K KG + + K
Sbjct: 115 GKKGEDKTTQKDTTDSESELKQGKKDSKKGKDIEK-GKEEKLDAKKDSK-KGKKDAEKGK 172
Query: 1254 HTASESDEQQWPEEKRLKED----------ILENEDEQNSPPKKGKRGRPPKPLG----- 1298
+A+ES++++ +K K+D E+E E+ K K+G+ G
Sbjct: 173 DSATESEDEKGGAKKDNKKDKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAI 232
Query: 1299 ------GGTPKEEPTMKTSKKGSKKKSGPPAPEE---EEEEERQSGNTEQKSKSKQHRVS 1349
K+E K + KG + K +E ++++++ +T+ SK + S
Sbjct: 233 ELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKES 292
Query: 1350 RR-AQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATK 1402
++ A + A+ E + +K + +K + KKN + K A K
Sbjct: 293 KKDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKK 346
Score = 39.3 bits (90), Expect = 0.028
Identities = 50/235 (21%), Positives = 94/235 (40%), Gaps = 17/235 (7%)
Query: 1123 GKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHS 1182
G+ KTT ++ GK+ K +E + S KG+ D+ + S
Sbjct: 118 GEDKTTQKDTTDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSK---KGKKDAEKGKDS 174
Query: 1183 --ENEDYTMSSPLPGKKSDKRDDS----DLVRSELEKPRGRKKTPVTEQEEKLGMDDLTK 1236
E+ED + KK DK+D + SE EK K + +++ K G D +
Sbjct: 175 ATESEDEKGGAKKDNKK-DKKDSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIE 233
Query: 1237 L----VQEQKPKGSQRSRKRGHTASES--DEQQWPEEKRLKEDILENEDEQNSPPKKGKR 1290
L E+K + ++ +G + ++ D ++ + K+ K+ + + KK +
Sbjct: 234 LQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKDDVKKESK 293
Query: 1291 GRPPKPLGGGTPKE-EPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSK 1344
K K+ E SKK +KK + A ++ ++ ++ + K K K
Sbjct: 294 KDATKDAKKVAKKDTEKESADSKKDAKKNAKKDAKKDAKKNAKKDEKKDAKKKGK 348
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 57.8 bits (138), Expect = 8e-08
Identities = 57/248 (22%), Positives = 106/248 (42%), Gaps = 24/248 (9%)
Query: 1183 ENEDYTMS-SPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQ 1241
+++DY S P +K K+ ++ +V + K G+ P ++L + L +E+
Sbjct: 582 KSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEK 641
Query: 1242 KPKGSQRSRKRGHTASESDEQQWPEE------KRLKEDILENEDEQNSP-PKKGKRGRPP 1294
K K +++K E E++ P+E ++ ++ E + + +P PK K+
Sbjct: 642 KKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSSNK 701
Query: 1295 KPLGGGTPKEEPTMKTSKKGSKK----KSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSR 1350
KP + ++ K +GS+ K+ PP+P EE+E+ QK +S + +
Sbjct: 702 KPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDED----PGVQKRRSSRQVKRK 757
Query: 1351 RAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVG------RSKQAATKEN 1404
R + E S E GR PS T Q + G S ++ K+
Sbjct: 758 RYTEDLEFKISD--EEADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMSSRSVKKQK 815
Query: 1405 DSSEEVDV 1412
+S EEV++
Sbjct: 816 ESGEEVEI 823
Score = 45.4 bits (106), Expect = 4e-04
Identities = 60/281 (21%), Positives = 106/281 (37%), Gaps = 61/281 (21%)
Query: 1177 SEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSE--LEKPRGRKKTPVTEQEEKLGMDDL 1234
S H ++ + P P K SE LEKP + + DD
Sbjct: 527 SSPPHPHHQPWAQLHPSPQNTPQKVPVHQHSPSEPFLEKPVPDMTQVSGPNAQLVKSDDY 586
Query: 1235 TKLVQEQKPKGSQRSRKRGHTASESDEQQWPEE--------KRLKEDILENEDEQNSPPK 1286
+ EQ+P+ ++ +K H +E + + ++ + L + L+ E+ K
Sbjct: 587 LPSI-EQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNSLDGSQEEKKKKK 645
Query: 1287 KGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQH 1346
+ K + PK PKE P K K K P P+E +E++ ++ + KS
Sbjct: 646 RSKAKKDPKE-----PKE-PKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKS----- 694
Query: 1347 RVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDS 1406
S+++ + E+SA+ KK V G++ E
Sbjct: 695 --SKKSSNKKPDSEASAL-----------------------KKKVNKGKT------EGSE 723
Query: 1407 SEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRERR 1447
+ ++D SP P EE E+ V +RRS+++ +R
Sbjct: 724 NSDLDKTPPPSP----PPEEDEDPGVQ----KRRSSRQVKR 756
Score = 34.7 bits (78), Expect = 0.68
Identities = 32/152 (21%), Positives = 63/152 (41%), Gaps = 15/152 (9%)
Query: 1113 PPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKG 1172
P E K P +PKT A P K+++T + + ++ +S+ S +K
Sbjct: 656 PKEPKEKKEPKEPKTPK---APKIPKEPKEKKAKTATPKPKSSKKSSNKKPDSEASALKK 712
Query: 1173 RLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMD 1232
+++ + + SEN D + P P ++ +D P +K+ + + K +
Sbjct: 713 KVNKGKTEGSENSDLDKTPP-PSPPPEEDED----------PGVQKRRSSRQVKRKRYTE 761
Query: 1233 DLT-KLVQEQKPKGSQRSRKRGHTASESDEQQ 1263
DL K+ E+ R S+S++Q+
Sbjct: 762 DLEFKISDEEADDADAAGRDSPSNTSQSEQQE 793
>gi|190014586 PC4 and SFRS1 interacting protein 1 isoform 1 [Homo
sapiens]
Length = 333
Score = 57.4 bits (137), Expect = 1e-07
Identities = 53/242 (21%), Positives = 106/242 (43%), Gaps = 43/242 (17%)
Query: 1210 ELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKR 1269
E+E+ T+ EEK +D+TK V PK ++R RKR ++++Q EE
Sbjct: 109 EVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGRKR-----KAEKQVETEEAG 163
Query: 1270 LKEDILENEDEQNSPPKKGKRGRP-------PKPLGGGTPKEEPTM----------KTSK 1312
+ + + + SP KRGRP PKP G ++P K+ K
Sbjct: 164 VVTTATASVNLKVSP----KRGRPAATEVKIPKPRGRPKMVKQPCPSESDIITEEDKSKK 219
Query: 1313 KGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQ 1372
KG ++K P+++EE +++ ++ K+ + + + + ++ + + ST + +
Sbjct: 220 KGQEEKQPKKQPKKDEEGQKEEDKPRKEPDKKEGK--KEVESKRKNLAKTGVTSTSDSEE 277
Query: 1373 KGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEV 1432
+G + +K + GR+ Q A + N + +G + ++ +EE++
Sbjct: 278 EG--------DDQEGEKKRKGGRNFQTAHRRN-------MLKGQHEKEAADRKRKQEEQM 322
Query: 1433 ST 1434
T
Sbjct: 323 ET 324
Score = 47.8 bits (112), Expect = 8e-05
Identities = 68/292 (23%), Positives = 113/292 (38%), Gaps = 30/292 (10%)
Query: 1088 PKDPVLPARFFTQPDKNFSNTKNYLP-PEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQ 1146
P LP FF + F K+ P E K + GKP N N+ L +
Sbjct: 35 PPTNKLPIFFFGTHETAFLGPKDIFPYSENKEKY--GKP---NKRKGFNEGLWEIDNNPK 89
Query: 1147 TKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSE---NEDYTMSSPLPGKKSDKRDD 1203
K S + + S++S+ + + + DH E NED T + + K+ +R
Sbjct: 90 VKFSSQQAATKQSNASSDVEVEEKETSVSKEDTDHEEKASNEDVTKAVDITTPKAARRGR 149
Query: 1204 SDLVRSELEKPRGRKKTPVT-----EQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASE 1258
++E T T + K G T+ V+ KP+G + K+ SE
Sbjct: 150 KRKAEKQVETEEAGVVTTATASVNLKVSPKRGRPAATE-VKIPKPRGRPKMVKQ-PCPSE 207
Query: 1259 SDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKK--GSK 1316
SD ++ + K + E + PKK + G+ + P++EP K KK SK
Sbjct: 208 SDIITEEDKSKKKG---QEEKQPKKQPKKDEEGQKEE----DKPRKEPDKKEGKKEVESK 260
Query: 1317 KKS-----GPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSA 1363
+K+ + EEE + Q G ++K RR + + + +A
Sbjct: 261 RKNLAKTGVTSTSDSEEEGDDQEGEKKRKGGRNFQTAHRRNMLKGQHEKEAA 312
>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
Length = 320
Score = 57.4 bits (137), Expect = 1e-07
Identities = 42/193 (21%), Positives = 83/193 (43%), Gaps = 6/193 (3%)
Query: 1200 KRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASES 1259
+R++SD E GRKK + + +G + K V++++ +G + + +
Sbjct: 116 EREESDGEYDEF----GRKKKKY--RGKAVGPASILKEVEDKESEGEEEDEDEDLSKYKL 169
Query: 1260 DEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKS 1319
DE + ++ L + L+ +E++S KK R K + + S S+ +S
Sbjct: 170 DEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRSRS 229
Query: 1320 GPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPS 1379
+ + R S +S+ + R S R+ + + SP + S+ S+P++ R R
Sbjct: 230 RSRSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSR 289
Query: 1380 KTPSPSQPKKNVR 1392
S S +K R
Sbjct: 290 SRSSSSGDRKKRR 302
Score = 36.2 bits (82), Expect = 0.24
Identities = 27/122 (22%), Positives = 49/122 (40%), Gaps = 1/122 (0%)
Query: 1325 EEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSP 1384
+ EEE+ + ++S+SK R+ R+ SP SS S +S + S++ S
Sbjct: 186 DASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSSSPSSSRSRS-RSRSRSSSSSQSRSRSS 244
Query: 1385 SQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKR 1444
S+ + R +S+ ++ SS SS + S+ R++ R
Sbjct: 245 SRERSRSRGSKSRSSSRSHRGSSSPRKRSYSSSSSSPERNRKRSRSRSSSSGDRKKRRTR 304
Query: 1445 ER 1446
R
Sbjct: 305 SR 306
Score = 35.4 bits (80), Expect = 0.40
Identities = 35/170 (20%), Positives = 64/170 (37%), Gaps = 5/170 (2%)
Query: 1243 PKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTP 1302
PK ++ + G+ ++ + +R + D +E + +GK P L
Sbjct: 91 PKYAKLEERTGYGGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVED 150
Query: 1303 KEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGN-----TEQKSKSKQHRVSRRAQQRAE 1357
KE + + K E+E++ + N E +K K +R SR + +
Sbjct: 151 KESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSH 210
Query: 1358 SPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSS 1407
S SS S S+ + R R + S ++ RS+ +K SS
Sbjct: 211 SRSSSRSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 57.0 bits (136), Expect = 1e-07
Identities = 73/360 (20%), Positives = 141/360 (39%), Gaps = 25/360 (6%)
Query: 1080 STTYSLESPKDPVLPARFFTQPDKNFSNTKNYLP-PEMKSFFTPGKPKTTNVLGAVNKPL 1138
ST Y++ + + F QP + +P P +K + + L KPL
Sbjct: 493 STQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPL 552
Query: 1139 SSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKS 1198
S + ++K E P + K + + +E + +P K+
Sbjct: 553 PSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEE 612
Query: 1199 DKRDDSDLVRSELE--KPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTA 1256
+++ + KP+ K+ V ++E K+ +D K +++KPK + ++K T
Sbjct: 613 PSPVKAEVAEKQATDVKPKAAKEKTV-KKETKVKPED--KKEEKEKPK-KEVAKKEDKTP 668
Query: 1257 SESDEQQWPEE--KRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKG 1314
+ +E+ EE K +K++I ++E+ P K+ K+ PPK + KEE KK
Sbjct: 669 IKKEEKPKKEEVKKEVKKEI--KKEEKKEPKKEVKKETPPKEVKKEVKKEE------KKE 720
Query: 1315 SKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKG 1374
KK EE+E +++ + +K +S + A P+ E +
Sbjct: 721 VKK--------EEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVA 772
Query: 1375 RGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVST 1434
G+P + KK + + AA ++ V G + + + E E +S+
Sbjct: 773 AGKPKEKGKIKVIKKEGKAAEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSLMSS 832
Score = 48.5 bits (114), Expect = 5e-05
Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 19/228 (8%)
Query: 1224 EQEEKLGMDDLTKLVQEQKPKGSQRSRKRG--HTASESDEQQWPEE--------KRLKED 1273
E EK G+DD+ K E + G + S + G +E++E + PEE K
Sbjct: 913 EPVEKQGVDDIEKF--EDEGAGFEESSETGDYEEKAETEEAEEPEEDGEEHVCVSASKHS 970
Query: 1274 ILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQ 1333
E+E+ + R + G EE + +KG ++S A EE++ E+ +
Sbjct: 971 PTEDEESAKAEADAYIREKRESVASGDDRAEEDMDEAIEKGEAEQSEEEADEEDKAEDAR 1030
Query: 1334 SGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQK--GRGRPSKTPSPSQPKKNV 1391
E + + V + AE+ + +TP K G P + P+ S + +
Sbjct: 1031 EEEYEPEKMEAEDYVMAVVDKAAEAGGAEEQYGFLTTPTKQLGAQSPGREPASSIHDETL 1090
Query: 1392 RVGRSKQA-ATKENDSSEEVDVFQGSS----PVDDIPQEETEEEEVST 1434
G +A A+ E + ++ + F +S +I E T +E+ST
Sbjct: 1091 PGGSESEATASDEENREDQPEEFTATSGYTQSTIEISSEPTPMDEMST 1138
Score = 43.9 bits (102), Expect = 0.001
Identities = 54/287 (18%), Positives = 107/287 (37%), Gaps = 30/287 (10%)
Query: 1174 LDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDD 1233
LD + + +D T P P K K R L+ + +E K +
Sbjct: 508 LDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPLPSKSVRKESKEETPE 567
Query: 1234 LTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRP 1293
+TK+ +KP + K ++K +K + + E+ P K+
Sbjct: 568 VTKVNHVEKPPKVESKEK----------VMVKKDKPIKTETKPSVTEKEVPSKE-----E 612
Query: 1294 PKPLGGGTPKEEPT---MKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSR 1350
P P+ +++ T K +K+ + KK PE+++EE+ + K + K
Sbjct: 613 PSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE 672
Query: 1351 RAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEV 1410
++ E + E + ++ + K P + KK V+ K+ +E + +E+
Sbjct: 673 EKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEI 732
Query: 1411 -----DVFQGSSPVDDI-------PQEETEEEEVSTVNVRRRSAKRE 1445
D + S+P+ + P+ +EE V +V K +
Sbjct: 733 KKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEK 779
Score = 31.6 bits (70), Expect = 5.8
Identities = 30/118 (25%), Positives = 51/118 (43%), Gaps = 21/118 (17%)
Query: 1268 KRLKEDILEN--------EDEQNSPPKKGK-RGRP----PKPLG--GGTPKEEPTMKTSK 1312
K LK+D+ E + + +SP KK + +P PKP G + K K
Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK 2292
Query: 1313 KGSKKKSGPPAPEEE------EEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAI 1364
K S +K+ P E EE+++++ N S SK + + ++ +SSA+
Sbjct: 2293 KESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKSSAV 2350
>gi|48255931 hepatoma-derived growth factor-related protein 2 isoform
1 [Homo sapiens]
Length = 671
Score = 56.6 bits (135), Expect = 2e-07
Identities = 70/328 (21%), Positives = 129/328 (39%), Gaps = 41/328 (12%)
Query: 1135 NKPLSSAGKQSQTKSSRMETVSNASSSSN-----PSSPGRIKGRLDSSEMDHSENEDYTM 1189
+K ++G + +T + +M A +S+ SP + SSE + + ++D+T
Sbjct: 147 DKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFT- 205
Query: 1190 SSPLPGKKSDKRDDSDLVRSELEKPRG---RKKTPVTEQEEKLGMDDLTKLVQEQKPKGS 1246
P KK+ VR+ P G +KK P + D K +P
Sbjct: 206 ----PEKKA-------AVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAK----PEPVAM 250
Query: 1247 QRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEE- 1305
RS ++S S + +K + E+ P +G++ +P +P + +
Sbjct: 251 ARSASSSSSSSSSSDSDVSVKKPPRG---RKPAEKPLPKPRGRKPKPERPPSSSSSDSDS 307
Query: 1306 ------PTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESP 1359
K + +++ E+EEE R+ E++ K ++ + R + S
Sbjct: 308 DEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSG 367
Query: 1360 ESSA------IESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVF 1413
SS E + +KGRGR + S S+P+ + +K++A K SS E
Sbjct: 368 GSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELE-REAKKSAKKPQSSSTEPARK 426
Query: 1414 QGSSPVDDIPQEETEEEEVSTVNVRRRS 1441
G P+E+ + + V R+RS
Sbjct: 427 PGQKEKRVRPEEKQQAKPVKVERTRKRS 454
Score = 51.2 bits (121), Expect = 7e-06
Identities = 66/270 (24%), Positives = 108/270 (40%), Gaps = 50/270 (18%)
Query: 1120 FTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEM 1179
FTP K V PL K+ +S ++ ++ S + P + SS
Sbjct: 204 FTPEKKAA--VRAPRRGPLGGRKKKKAPSASDSDSKAD-SDGAKPEPVAMARSASSSSSS 260
Query: 1180 DHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQ 1239
S + D ++ P G+K ++ L KPRGRK P D ++ +
Sbjct: 261 SSSSDSDVSVKKPPRGRKPAEKP--------LPKPRGRKPKPERPPSSSSSDSDSDEVDR 312
Query: 1240 EQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGG 1299
+ K +R+R A EQ+ E +RL+E + ++E+ ++ RG + GG
Sbjct: 313 ISEWKRRDEARRRELEARRRREQE-EELRRLRE---QEKEEKERRRERADRGEAERGSGG 368
Query: 1300 GTPKE-----EPTMKTSKKGSKKKSGPPA-----PEEEEEEER-------QSGNTE---- 1338
+ E EP K +KG + GPP+ PE E E E QS +TE
Sbjct: 369 SSGDELREDDEPVKKRGRKGRGR--GPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARK 426
Query: 1339 -----------QKSKSKQHRVSRRAQQRAE 1357
+K ++K +V R ++R+E
Sbjct: 427 PGQKEKRVRPEEKQQAKPVKV-ERTRKRSE 455
Score = 38.1 bits (87), Expect = 0.062
Identities = 54/244 (22%), Positives = 90/244 (36%), Gaps = 37/244 (15%)
Query: 1132 GAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSS---------------------PGRI 1170
GA +P++ A S + SS + S+ S P P
Sbjct: 242 GAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSS 301
Query: 1171 KGRLDSSEMDHS---ENEDYTMSSPLPGKKSDKRDDSDLVR-----SELEKPRGRKKTPV 1222
DS E+D + D L ++ +R+ + +R + EK R R++
Sbjct: 302 SSDSDSDEVDRISEWKRRDEARRRELEARR--RREQEEELRRLREQEKEEKERRRERADR 359
Query: 1223 TEQEEKLGMDDLTKLVQEQKP--KGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDE 1280
E E G +L ++ +P K ++ R RG +S E + E+ K+ + +
Sbjct: 360 GEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSS 419
Query: 1281 QNSPPKKG----KRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGN 1336
P +K KR RP + K E T K S+ S + E EE+ Q +
Sbjct: 420 STEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLH 479
Query: 1337 TEQK 1340
+E K
Sbjct: 480 SEIK 483
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 56.6 bits (135), Expect = 2e-07
Identities = 67/343 (19%), Positives = 127/343 (37%), Gaps = 49/343 (14%)
Query: 1139 SSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKS 1198
S +G S + + SNAS S + G+ + E+ ++ED S
Sbjct: 21 SDSGSDSDSDQENAASGSNASGSESDQDERGDSGQPSNKELFGDDSEDEGASHHSGSDNH 80
Query: 1199 DKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQE--QKPKGSQRSRKRGHTA 1256
+R D+ RSE + + ++ ++ G + E + GS S G
Sbjct: 81 SERSDN---RSEASERSDHEDNDPSDVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEK 137
Query: 1257 SESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKE------------ 1304
+ SD+++W E K D ++E QNS ++ +G L E
Sbjct: 138 AHSDDEKWGRED--KSDQSDDEKIQNSDDEERAQGSDEDKLQNSDDDEKMQNTDDEERPQ 195
Query: 1305 ----EPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPE 1360
E + ++ + P + ++E++ S + EQ S + ++ +R ++ +
Sbjct: 196 LSDDERQQLSEEEKANSDDERPVASDNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASD 255
Query: 1361 -----SSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKE--NDSSEEVDVF 1413
S E + RG S+ +KN S+ + E D+S +D+F
Sbjct: 256 EEHRHSDDEEEQDHKSESARGSDSEDEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLF 315
Query: 1414 QGS-----------------SPVDD--IPQEETEEEEVSTVNV 1437
G+ PVD+ +PQ++ EEE + +
Sbjct: 316 GGADDISSGSDGEDKPPTPGQPVDENGLPQDQQEEEPIPETRI 358
>gi|14249158 hepatoma-derived growth factor-related protein 2 isoform
2 [Homo sapiens]
Length = 670
Score = 56.6 bits (135), Expect = 2e-07
Identities = 70/328 (21%), Positives = 129/328 (39%), Gaps = 41/328 (12%)
Query: 1135 NKPLSSAGKQSQTKSSRMETVSNASSSSN-----PSSPGRIKGRLDSSEMDHSENEDYTM 1189
+K ++G + +T + +M A +S+ SP + SSE + + ++D+T
Sbjct: 147 DKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSDQDFT- 205
Query: 1190 SSPLPGKKSDKRDDSDLVRSELEKPRG---RKKTPVTEQEEKLGMDDLTKLVQEQKPKGS 1246
P KK+ VR+ P G +KK P + D K +P
Sbjct: 206 ----PEKKA-------AVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAK----PEPVAM 250
Query: 1247 QRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEE- 1305
RS ++S S + +K + E+ P +G++ +P +P + +
Sbjct: 251 ARSASSSSSSSSSSDSDVSVKKPPRG---RKPAEKPLPKPRGRKPKPERPPSSSSSDSDS 307
Query: 1306 ------PTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESP 1359
K + +++ E+EEE R+ E++ K ++ + R + S
Sbjct: 308 DEVDRISEWKRRDEARRRELEARRRREQEEELRRLREQEKEEKERRRERADRGEAERGSG 367
Query: 1360 ESSA------IESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVF 1413
SS E + +KGRGR + S S+P+ + +K++A K SS E
Sbjct: 368 GSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELE-REAKKSAKKPQSSSTEPARK 426
Query: 1414 QGSSPVDDIPQEETEEEEVSTVNVRRRS 1441
G P+E+ + + V R+RS
Sbjct: 427 PGQKEKRVRPEEKQQAKPVKVERTRKRS 454
Score = 51.2 bits (121), Expect = 7e-06
Identities = 66/270 (24%), Positives = 108/270 (40%), Gaps = 50/270 (18%)
Query: 1120 FTPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEM 1179
FTP K V PL K+ +S ++ ++ S + P + SS
Sbjct: 204 FTPEKKAA--VRAPRRGPLGGRKKKKAPSASDSDSKAD-SDGAKPEPVAMARSASSSSSS 260
Query: 1180 DHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQ 1239
S + D ++ P G+K ++ L KPRGRK P D ++ +
Sbjct: 261 SSSSDSDVSVKKPPRGRKPAEKP--------LPKPRGRKPKPERPPSSSSSDSDSDEVDR 312
Query: 1240 EQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGG 1299
+ K +R+R A EQ+ E +RL+E + ++E+ ++ RG + GG
Sbjct: 313 ISEWKRRDEARRRELEARRRREQE-EELRRLRE---QEKEEKERRRERADRGEAERGSGG 368
Query: 1300 GTPKE-----EPTMKTSKKGSKKKSGPPA-----PEEEEEEER-------QSGNTE---- 1338
+ E EP K +KG + GPP+ PE E E E QS +TE
Sbjct: 369 SSGDELREDDEPVKKRGRKGRGR--GPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARK 426
Query: 1339 -----------QKSKSKQHRVSRRAQQRAE 1357
+K ++K +V R ++R+E
Sbjct: 427 PGQKEKRVRPEEKQQAKPVKV-ERTRKRSE 455
Score = 38.1 bits (87), Expect = 0.062
Identities = 54/244 (22%), Positives = 90/244 (36%), Gaps = 37/244 (15%)
Query: 1132 GAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSS---------------------PGRI 1170
GA +P++ A S + SS + S+ S P P
Sbjct: 242 GAKPEPVAMARSASSSSSSSSSSDSDVSVKKPPRGRKPAEKPLPKPRGRKPKPERPPSSS 301
Query: 1171 KGRLDSSEMDHS---ENEDYTMSSPLPGKKSDKRDDSDLVR-----SELEKPRGRKKTPV 1222
DS E+D + D L ++ +R+ + +R + EK R R++
Sbjct: 302 SSDSDSDEVDRISEWKRRDEARRRELEARR--RREQEEELRRLREQEKEEKERRRERADR 359
Query: 1223 TEQEEKLGMDDLTKLVQEQKP--KGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDE 1280
E E G +L ++ +P K ++ R RG +S E + E+ K+ + +
Sbjct: 360 GEAERGSGGSSGDELREDDEPVKKRGRKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSS 419
Query: 1281 QNSPPKKG----KRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGN 1336
P +K KR RP + K E T K S+ S + E EE+ Q +
Sbjct: 420 STEPARKPGQKEKRVRPEEKQQAKPVKVERTRKRSEGFSMDRKVEKKKEPSVEEKLQKLH 479
Query: 1337 TEQK 1340
+E K
Sbjct: 480 SEIK 483
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 55.5 bits (132), Expect = 4e-07
Identities = 75/327 (22%), Positives = 115/327 (35%), Gaps = 42/327 (12%)
Query: 1138 LSSAGKQSQTKSSRMETVSNASS----------SSNPSSP-GRIKGRLDSSEMDHSENED 1186
LS G+ SQ++S N S S NPS R S E DH +
Sbjct: 323 LSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSS 382
Query: 1187 YTMSS--PLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPK 1244
S G + +RD S + R R ++P + D ++ K +
Sbjct: 383 PRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKAR-------DRSRSRSPNKAR 435
Query: 1245 GSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKE 1304
RSR + A + + P + R + SP K R R P KE
Sbjct: 436 DCSRSRSP-YKARDRSRSRSPNKAR-------DHSRSRSPNKARDRSRSRSP-----SKE 482
Query: 1305 EPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSR-----RAQQRAESP 1359
S+ GS K +ERQ + SK + HR SR R ++++ SP
Sbjct: 483 RDH---SQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSP 539
Query: 1360 ESSAIESTQSTPQKGRG-RPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSP 1418
S +P + R R S++PS + ++ R ++ + SSEE D + SP
Sbjct: 540 NKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSP 599
Query: 1419 VDDIPQEETEEEEVSTVNVRRRSAKRE 1445
+ R R+ +E
Sbjct: 600 NKQSGYSRPRASSKEKAHSRSRTPSKE 626
Score = 50.1 bits (118), Expect = 2e-05
Identities = 69/350 (19%), Positives = 135/350 (38%), Gaps = 45/350 (12%)
Query: 1122 PGKPKTTNVLGAVNKPLSSAGKQ---------SQTK-SSRMETVSNASSSSNPSSPGRIK 1171
P K K+ N + ++ + S G+ S T+ SSR+++ + AS+ S P S
Sbjct: 226 PSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQS----- 280
Query: 1172 GRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGM 1231
HS++ S K++ R S + + R R + + Q +G
Sbjct: 281 ---------HSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQ---MGR 328
Query: 1232 DDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRG 1291
++ + K + R+ +RG + + S + D + S + + G
Sbjct: 329 HSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESG 388
Query: 1292 RPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEER-QSGNTEQKSKSKQHRVSR 1350
R G + + + S ++ +S +P + + R +S N + +
Sbjct: 389 RSQS--GSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA 446
Query: 1351 RAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVG--------RSKQAATK 1402
R + R+ SP + S +P K R R S++ SPS+ + + ++G R ++ +K
Sbjct: 447 RDRSRSRSPNKARDHSRSRSPNKARDR-SRSRSPSKERDHSQLGSPSKERDHRRSRSPSK 505
Query: 1403 E------NDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRER 1446
E SS+E D + SP + + ++ + RS ER
Sbjct: 506 ERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEER 555
Score = 50.1 bits (118), Expect = 2e-05
Identities = 61/284 (21%), Positives = 113/284 (39%), Gaps = 31/284 (10%)
Query: 1121 TPGKPKTTNVLGAVNKPLSSAGKQSQTKS---SRMETVSNASSSSNPSSP----GRIKGR 1173
+P K + + + NK + +S K+ SR + + A S SP R + R
Sbjct: 394 SPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR 453
Query: 1174 LDSSEMDHSENEDYTMSSPLPGKKSD--KRDDSDLVRSELEKPRGRKKTPVTEQEEKLGM 1231
+ DHS + + +S +RD S L E+ R ++P E++ +
Sbjct: 454 SPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSR 513
Query: 1232 DDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRG 1291
+K ++ + + R+R + S + E+ + + E E E Q+ P K +
Sbjct: 514 SS-SKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSE---EREHRQSRSPSKERDR 569
Query: 1292 RPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSR- 1350
R + +P +E + S+ S+++ +QSG + ++ SK+ SR
Sbjct: 570 RRWR-----SPSKERERRQSRSSSEERDH----SRSRSPNKQSGYSRPRASSKEKAHSRS 620
Query: 1351 --------RAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQ 1386
+Q R S ES +ST + P++T S SQ
Sbjct: 621 RTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQ 664
Score = 49.7 bits (117), Expect = 2e-05
Identities = 70/353 (19%), Positives = 130/353 (36%), Gaps = 25/353 (7%)
Query: 1106 SNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGKQSQTKS---SRMETVSNASSSS 1162
S K+Y P EM S + K+ N ++P S + +S +S S+ T S S S
Sbjct: 252 SREKSYSPTEMSS-----RVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHS 306
Query: 1163 NPSSPGRIKGRLDSSEMD----HSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRK 1218
+ R + R + HS++ ++ ++ +R S K R
Sbjct: 307 WKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHS 366
Query: 1219 KTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENE 1278
+ + +E + + GS +++R H+ S S + + R + +
Sbjct: 367 HSRSSSKERDHRGSSSPRKESGRSQSGSP-NKQRDHSRSRSPNKA-RDRSRSRSPYKARD 424
Query: 1279 DEQNSPPKKGK---RGRPPKPLGGGTPKEEPTMKT--SKKGSKKKSGPPAPEEEEEEERQ 1333
++ P K + R R P + P S+ S K+ + +ER
Sbjct: 425 RSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERD 484
Query: 1334 SGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRV 1393
SK + HR SR + S E +S S+ ++ R S++PS + ++ R
Sbjct: 485 HSQLGSPSKERDHRRSR-----SPSKERQCRQSRSSSKERDHRR-SRSPSKERQRRQSRS 538
Query: 1394 GRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRSAKRER 1446
++ ++ SEE + Q SP + + + RS+ ER
Sbjct: 539 PNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEER 591
Score = 45.8 bits (107), Expect = 3e-04
Identities = 65/300 (21%), Positives = 114/300 (38%), Gaps = 32/300 (10%)
Query: 1139 SSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKS 1198
S S ++SS E SSS S GR + + + DHS + + +S
Sbjct: 360 SKERSHSHSRSSSKERDHRGSSSPRKES-GRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
Query: 1199 D--KRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTA 1256
RD S + R ++P ++ K + + ++R R +
Sbjct: 419 PYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP-NKARDHSRSRSPNKARDRSRSR 477
Query: 1257 SESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLG-------GGTPKEEPTMK 1309
S S E+ + +L E + ++ P K ++ R + +P +E +
Sbjct: 478 SPSKER---DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRR 534
Query: 1310 TSKKGSKKKSGPPA---PEEEEEEERQSGNTEQ-----KSKSKQHRVSRRAQQRAESPES 1361
S+ +K++ + EE E + +S + E+ +S SK+ R Q R+ S E
Sbjct: 535 QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKER---ERRQSRSSSEER 591
Query: 1362 SAIESTQSTPQKGRGRP---SKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSP 1418
S Q G RP SK + S+ + + G Q+ T SS+E D Q + P
Sbjct: 592 DHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRT----SSKESDPSQSTVP 647
Score = 44.7 bits (104), Expect = 7e-04
Identities = 59/281 (20%), Positives = 97/281 (34%), Gaps = 29/281 (10%)
Query: 1121 TPGKPKTTNVLGAVNKPLSSAGKQSQTKS---SRMETVSNASSSSNPSSPG----RIKGR 1173
+P K + + + NK + +S K+ SR + + A S SP R + R
Sbjct: 418 SPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSR 477
Query: 1174 LDSSEMDHSE-----NEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEK 1228
S E DHS+ E S P K+ R S E+ R ++P E++ +
Sbjct: 478 SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRS---SSKERDHRRSRSPSKERQRR 534
Query: 1229 LGMDDLTKL--VQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPK 1286
+ Q + P + R+ + E D ++W + +E + +S +
Sbjct: 535 QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERE---RRQSRSSSEER 591
Query: 1287 KGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQH 1346
R R P G + SK+K+ + +E T K
Sbjct: 592 DHSRSRSPNKQSG--------YSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQ 643
Query: 1347 RVSRRAQQRAESPESSAIESTQSTPQKGRGR-PSKTPSPSQ 1386
R+ SP ++ S TP K PS PS Q
Sbjct: 644 STVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQ 684
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 55.1 bits (131), Expect = 5e-07
Identities = 65/315 (20%), Positives = 124/315 (39%), Gaps = 49/315 (15%)
Query: 1180 DHSENEDYTMSSPLPGKKSDKRDDSDLVRSELE-KPRGRKKTPVTEQEEKLGMDD---LT 1235
+++E E + G+K K+ D ELE K KKT + E G DD
Sbjct: 85 ENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFN 144
Query: 1236 KLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQN------SPPKKGK 1289
KL ++ K K + ++K + + D + +E+ E+ DE + KK +
Sbjct: 145 KLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQ 204
Query: 1290 RGRPPKPLGGGTPKEEPTMK----TSKKGSKKKSGPPAPEEE--------EEEERQSGNT 1337
+ +P + G ++ + K KK KK+ +EE E+EE ++G
Sbjct: 205 KNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK 264
Query: 1338 EQKSKSKQHR----------------VSRRAQQRAESPESSAIESTQSTPQKGRGRPSKT 1381
+Q + + R V ++++AE+P +A E +K + + K
Sbjct: 265 DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETP--TAAEDDNEGDKKKKDKKKKK 322
Query: 1382 PSPSQPKKNVRVGRSKQ---------AATKENDSSEEVDVFQGSSPVDDIPQEETEEEEV 1432
+ +K + G SK A KE + ++ + + ++++ + EEE +
Sbjct: 323 GEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERL 382
Query: 1433 STVNVRRRSAKRERR 1447
R+ K + R
Sbjct: 383 EQEKRERKKQKEKER 397
Score = 49.7 bits (117), Expect = 2e-05
Identities = 67/297 (22%), Positives = 118/297 (39%), Gaps = 32/297 (10%)
Query: 1144 QSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDD 1203
QS+ K S+ + S G I + +E + +D KK K+
Sbjct: 266 QSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKK---KKDKKKKK 322
Query: 1204 SDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQ 1263
+ E EK +G K V +E L KL +E++ ++ R+ +E
Sbjct: 323 GEKEEKEKEKKKGPSKATVKAMQEALA-----KLKEEEE----RQKREEEERIKRLEEL- 372
Query: 1264 WPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKK---KSG 1320
E KR +E+ LE E + K+ +R K G K + + + + K G
Sbjct: 373 --EAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQG 430
Query: 1321 PPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPE-SSAIESTQSTPQKGRGRPS 1379
P ++ +++ ++K K + Q+ ES E S ++E + +G P
Sbjct: 431 VEVPSKDSLPKKRPIYEDKKRK--------KIPQQLESKEVSESMELCAAVEVMEQGVPE 482
Query: 1380 K--TPSPSQPKKNVRV---GRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEE 1431
K TP P +P++ G A ++ +E+V+ + V + P+EE EEEE
Sbjct: 483 KEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEE 539
Score = 43.9 bits (102), Expect = 0.001
Identities = 53/269 (19%), Positives = 110/269 (40%), Gaps = 25/269 (9%)
Query: 1182 SENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQ 1241
S NED S + K + + R + ++ + + + ++E + G D +K + Q
Sbjct: 214 SGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQ 273
Query: 1242 KP--KGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGG 1299
+ + + +S+ T ++ E ED +NE ++ KK K+G +
Sbjct: 274 RKFEEETVKSKVTVDTGVIPASEEKAETPTAAED--DNEGDKKKKDKKKKKGEKEE---- 327
Query: 1300 GTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESP 1359
KE+ K K + K + +EEEERQ + ++ R+ R + A+
Sbjct: 328 ---KEKEKKKGPSKATVKAMQEALAKLKEEEERQ-------KREEEERIKRLEELEAKRK 377
Query: 1360 ESSAIESTQSTPQKGRGRPSKTPSPSQPK---KNVRVGRSKQAATKENDSSEEVDVFQGS 1416
E +E + +K + + K + K K+ R R++ AT + ++ V+V
Sbjct: 378 EEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEV---- 433
Query: 1417 SPVDDIPQEETEEEEVSTVNVRRRSAKRE 1445
D +P++ E+ + ++ +E
Sbjct: 434 PSKDSLPKKRPIYEDKKRKKIPQQLESKE 462
Score = 40.4 bits (93), Expect = 0.012
Identities = 59/277 (21%), Positives = 108/277 (38%), Gaps = 34/277 (12%)
Query: 1169 RIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEK 1228
RIK RL+ E E E L +K +++ + R E K G+ T +++E +
Sbjct: 365 RIK-RLEELEAKRKEEER------LEQEKRERKKQKEKERKERLKKEGKLLTK-SQREAR 416
Query: 1229 LGMDDLTKLVQEQ-------------KPKGSQRSRKRGHTASESDEQQWPEEKRLKEDIL 1275
+ KL+Q Q +P + RK+ ES E E +++
Sbjct: 417 ARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVM 476
Query: 1276 EN---EDEQNSPPKKGKRGRPPKPLG------GGTPKEEPTMKTSKKGSKKKSGPPAPEE 1326
E E E+ PP + + + G + +E ++ +K + K P EE
Sbjct: 477 EQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEE 536
Query: 1327 EEEEERQSGNTEQKSKSKQHRVSRRAQQRAE--SPESSAIESTQSTPQKGRGRPSKTPSP 1384
EEEEE + +E++ + + + E S E + ++ P K S+ S
Sbjct: 537 EEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSD 596
Query: 1385 SQPKKNVRV-GRSKQAATKEN-DSSEEVDVFQGSSPV 1419
K R ++K+ K + S+ V+ + +P+
Sbjct: 597 DDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPI 633
Score = 32.0 bits (71), Expect = 4.4
Identities = 33/164 (20%), Positives = 67/164 (40%), Gaps = 33/164 (20%)
Query: 1298 GGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAE 1357
G G KE+ K+ KG KKK E+++ E + +S AQ
Sbjct: 28 GAGAAKEQEPQKS--KGKKKK-----------EKKKQDFDEDDILKELEELSLEAQGIKA 74
Query: 1358 SPESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSE----EVDVF 1413
E+ A++ T++ ++ + K K++ S++ K++ S + +V+++
Sbjct: 75 DRETVAVKPTENNEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMY 134
Query: 1414 QGSSPVDDIPQ----------------EETEEEEVSTVNVRRRS 1441
GS DD + + +EE+E ++ ++ RS
Sbjct: 135 SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERS 178
>gi|33620745 pre-mRNA cleavage complex II protein Pcf11 [Homo sapiens]
Length = 1555
Score = 55.1 bits (131), Expect = 5e-07
Identities = 68/297 (22%), Positives = 131/297 (44%), Gaps = 38/297 (12%)
Query: 1144 QSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMS---SPLPGKKSDK 1200
QS TK+S+ T+ + +S+ + ++ E+D +++ + S SPL K S
Sbjct: 324 QSDTKTSK--TIPSEKLNSSKQEKSKSGEKITKKELDQLDSKSKSKSKSPSPLKNKLSHT 381
Query: 1201 RD----DSDLVR-SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHT 1255
+D +S+ +R S++ K R K + ++ + G DD K +K K +++ K H
Sbjct: 382 KDLKNQESESMRLSDMNKRDPRLKKHLQDKTD--GKDDDVK----EKRKTAEKKDKDEHM 435
Query: 1256 ASESDEQQWPEEKRL-----KEDILENEDEQN------SPPKKGKRGRPPKP----LGGG 1300
S K + K+D + E E+ S +K R R PK +
Sbjct: 436 KSSEHRLAGSRNKIINGIVQKQDTITEESEKQGTKPGRSSTRKRSRSRSPKSRSPIIHSP 495
Query: 1301 TPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPE 1360
++ + K ++ S P A + + +QS E S++ R ++R+ ++
Sbjct: 496 KRRDRRSPKRRQRSMSPTSTPKAGKIRQSGAKQSHMEEFTPPSREDRNAKRSTKQDIRDP 555
Query: 1361 SSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATK------ENDSSEEVD 1411
++ + PQ+ + S T S ++PK+NV +S ++A + EN S ++VD
Sbjct: 556 RRMKKTEEERPQETTNQHS-TKSGTEPKENVENWQSSKSAKRWKSGWEENKSLQQVD 611
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 55.1 bits (131), Expect = 5e-07
Identities = 78/375 (20%), Positives = 141/375 (37%), Gaps = 73/375 (19%)
Query: 1122 PGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDH 1181
PG+P + +G SS G+ S +A S N PG G
Sbjct: 608 PGEPNKSKEVGGEKIVRSSGGRMDAPASG------SACSGLNKQEPGGSHG--------- 652
Query: 1182 SENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQ-- 1239
SE ED S P ++S K +K + KK+ +++ K ++ + +
Sbjct: 653 SETEDTGRSLPSKKERSGKSHRH-------KKKKKHKKSSKHKRKHKADTEEKSSKAESG 705
Query: 1240 EQKPKGSQRSRKRGHTASESDEQQWPEEK----------RLKEDILENEDEQNSPPKKGK 1289
E+ K +R RK+ +++ +D ++ P+ + R + ++ ++ P ++G
Sbjct: 706 EKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDDSQRRSLPAEEGS 765
Query: 1290 RGRPPKPLGGGTPKEE----------PTMKTSKKGSKK---------------------- 1317
G+ + GG + ++ P+ + G+K+
Sbjct: 766 SGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDASS 825
Query: 1318 -----KSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQ 1372
KS EEEEEE+ S ++ +S+S + S R+ +R+ S S A S QS
Sbjct: 826 HRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDA-SSDQSCYS 884
Query: 1373 KGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDV-FQGSSPVDDIPQEETEEEE 1431
+ R + S + RS + + SS+ + SS DD ++
Sbjct: 885 RQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRS 944
Query: 1432 VSTVNVRRRSAKRER 1446
S + R RS R R
Sbjct: 945 RSRSHTRERSRSRGR 959
Score = 52.0 bits (123), Expect = 4e-06
Identities = 86/371 (23%), Positives = 138/371 (37%), Gaps = 47/371 (12%)
Query: 1084 SLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVLGAVNKPLSSAGK 1143
S E PK P P FF K+ S + P FT +P + PL K
Sbjct: 526 SQEGPKHPTGP--FFPVLSKDESTALQW--PSELLIFTKAEPSISYSCN----PLYFDFK 577
Query: 1144 QSQTKSSRM---ETVSNASSSSNPSSPGRIKGRLDSSEMDHSE----NEDYTMSSPLPGK 1196
S+ K +R E + SSS G G + S+ E + M +P G
Sbjct: 578 LSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASGS 637
Query: 1197 KS---DKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRG 1253
+K++ SE E GR + ++E+ G K ++ K K S+ RK
Sbjct: 638 ACSGLNKQEPGGSHGSETEDT-GRS---LPSKKERSGKSHRHKKKKKHK-KSSKHKRKHK 692
Query: 1254 HTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKK 1313
E + EK K + + ++S P +RG P+P G G+P + ++
Sbjct: 693 ADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQD 752
Query: 1314 GSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQK 1373
S+++S P EE SG ++ + + + E P SS +
Sbjct: 753 DSQRRSLP-------AEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSC------QRRA 799
Query: 1374 GRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEEVS 1433
G R S++ SQP + +++D + + Q SP +EE E+
Sbjct: 800 GTKRSSRSSHRSQP----------SSGDEDSDDASSHRLHQ-KSPSQYSEEEEEEDSGSE 848
Query: 1434 TVNVRRRSAKR 1444
R RS +R
Sbjct: 849 HSRSRSRSGRR 859
Score = 43.9 bits (102), Expect = 0.001
Identities = 59/274 (21%), Positives = 98/274 (35%), Gaps = 49/274 (17%)
Query: 1140 SAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSD 1199
S + S +SSR S++ +SS+ S R + D S D+S+ S K+S
Sbjct: 856 SGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYSDR------SRRHSKRSH 909
Query: 1200 KRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGS----QRSRKRGHT 1255
DDSD S+ R + + DD + + + + +RSR RG +
Sbjct: 910 DSDDSDYASSKHRSKRHKYSS---------SDDDYSLSCSQSRSRSRSHTRERSRSRGRS 960
Query: 1256 ASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGS 1315
S S + + + + ++ + + R P + + GS
Sbjct: 961 RSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSP---------------SQRSGS 1005
Query: 1316 KKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQK-- 1373
+K+S E EER SG + R R++SP + +K
Sbjct: 1006 RKRSWG----HESPEERHSGRRD---------FIRSKIYRSQSPHYFRSGRGEGPGKKDD 1052
Query: 1374 GRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSS 1407
GRG SK P N+ GR + D +
Sbjct: 1053 GRGDDSKATGPPSQNSNIGTGRGSEGDCSPEDKN 1086
Score = 38.9 bits (89), Expect = 0.036
Identities = 43/242 (17%), Positives = 83/242 (34%), Gaps = 13/242 (5%)
Query: 1149 SSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVR 1208
SS + SSS + KG L S + S + S +DSD
Sbjct: 765 SSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDAS 824
Query: 1209 SELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASE---SDEQQWP 1265
S + + E+EE G + + + S RS +R +++S SD+ +
Sbjct: 825 SHRLHQKSPSQYSEEEEEEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYS 884
Query: 1266 EEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPK----------EEPTMKTSKKGS 1315
++ +D + +++ K + ++ ++ S+ S
Sbjct: 885 RQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRS 944
Query: 1316 KKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGR 1375
+ +S R S + +SK + + + QR+ S ST+S Q+
Sbjct: 945 RSRSHTRERSRSRGRSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSG 1004
Query: 1376 GR 1377
R
Sbjct: 1005 SR 1006
Score = 32.0 bits (71), Expect = 4.4
Identities = 66/330 (20%), Positives = 121/330 (36%), Gaps = 52/330 (15%)
Query: 1139 SSAGKQSQTKSSR--METVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGK 1196
S G + KSS ++ V ++ SSN LD + D + +++S L
Sbjct: 328 SEDGTKPDEKSSDQGLQKVGDSDGSSN----------LDGKKEDEDPQDGGSLASTLSKL 377
Query: 1197 KSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTA 1256
K KR++ + +P P + K L + ++ G + + A
Sbjct: 378 KRMKREEG----AGATEPEYYHYIPPAHCKVKPNFPFLLFMRASEQMDGDNTTHPKN--A 431
Query: 1257 SESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSK 1316
ES + P+ K ++ Q + + PK T EP+ SK +K
Sbjct: 432 PESKKGSSPKPK----SCIKAAASQGAEKTVSEVSEQPKE----TSMTEPSEPGSKAEAK 483
Query: 1317 KKSGPPAPEEEEEEERQSGNTEQKSKSKQHR-------VSRRAQQRAESP---------- 1359
K G ++ E Q + Q +S + + +Q+ + P
Sbjct: 484 KALGGDVSDQSLESHSQKVSETQMCESNSSKETSLATPAGKESQEGPKHPTGPFFPVLSK 543
Query: 1360 -ESSAIESTQSTPQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSP 1418
ES+A++ + PS + S + + ++ R+K A TK + +++ GSS
Sbjct: 544 DESTALQWPSELLIFTKAEPSISYSCNPLYFDFKLSRNKDARTKGTEKPKDI----GSSS 599
Query: 1419 VDDI----PQEETEEEEVSTVNVRRRSAKR 1444
D + P E + +EV + R S R
Sbjct: 600 KDHLQGLDPGEPNKSKEVGGEKIVRSSGGR 629
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 54.7 bits (130), Expect = 6e-07
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 40/262 (15%)
Query: 1124 KPKTTN-VLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSP-------GRIKGRLD 1175
KP T N VL + S+G ++ +KS + TV + ++P + IK L
Sbjct: 1189 KPVTENLVLSSHTGFCQSSGDEALSKSVPV-TVDDDDDDNDPENRIAKKMLLEEIKANLS 1247
Query: 1176 SSEMDHSENEDYTMSSPLPGKKSDKR-----------DDSDLVRSELEKPRGRKKT---P 1221
S E D S +++ GK++++ +SD E +KPR R +
Sbjct: 1248 SDE-DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHK 1306
Query: 1222 VTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQ 1281
+T + + G + TK + ++ KG R + + +SD Q E + E++ E+EDEQ
Sbjct: 1307 LTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQ----ESGVSEEVSESEDEQ 1362
Query: 1282 NSPPKKGKRGRPPKPLGGGTPKEE------------PTMKTSKKGSKKKSGPPAPEEEEE 1329
+ K+ + K++ S++ ++K EEEEE
Sbjct: 1363 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE 1422
Query: 1330 EERQSGNTEQKSKSKQHRVSRR 1351
EE + N + KS K + R+
Sbjct: 1423 EEEEDENDDSKSPGKGRKKIRK 1444
Score = 44.3 bits (103), Expect = 9e-04
Identities = 93/459 (20%), Positives = 161/459 (35%), Gaps = 48/459 (10%)
Query: 1012 EQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDV 1071
E+L + +E F I KN K + + K + D A+ + CD
Sbjct: 979 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1038
Query: 1072 AMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVL 1131
+ + SK+ Y E + +L + D + S+T+ Y E + + K +
Sbjct: 1039 SEDK-KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELR 1097
Query: 1132 GAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSS 1191
N LSS + +S + + SS N R + + + + S+
Sbjct: 1098 ERRN--LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1155
Query: 1192 P------LPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKG 1245
SD DD E + K PVTE L + T Q +
Sbjct: 1156 KRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK-PVTEN---LVLSSHTGFCQSSGDEA 1211
Query: 1246 SQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPP---KPLGGGTP 1302
+S T + D+ PE + K+ +LE S + G P K G
Sbjct: 1212 LSKSVPV--TVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQN 1269
Query: 1303 KEEPTMKTSKKGSKKKSGPPAPEEEEEEERQ------------SGNTEQKSKSKQHRVSR 1350
+E P + +K +S + E ++ R E+K+K K+H+ +
Sbjct: 1270 EENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVK 1329
Query: 1351 RAQQRAESPESSAIESTQST-----------PQKGRGRPSKTP-------SPSQPKKNVR 1392
+R S E S Q + Q+ R R +K S Q KK R
Sbjct: 1330 GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1389
Query: 1393 VGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEE 1431
+ + ++++ +SEE + + ++ +EE EE+E
Sbjct: 1390 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1428
Score = 41.6 bits (96), Expect = 0.006
Identities = 58/317 (18%), Positives = 118/317 (37%), Gaps = 48/317 (15%)
Query: 1140 SAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSD 1199
++ S + ++ SS P L S + D +S +P D
Sbjct: 1163 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1222
Query: 1200 KRDDSD--------LVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRK 1251
DD+D ++ E++ + ++ E + G K +E +++
Sbjct: 1223 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1282
Query: 1252 RGHTASESDEQQWPEEK-RLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKT 1310
+ S+S+E + P + RL L D ++ KK K PKE +K
Sbjct: 1283 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK------------PKEHKEVK- 1329
Query: 1311 SKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQST 1370
+ + + + E+ + ++SG +E+ S+S+ + + R S + + +E Q +
Sbjct: 1330 ----GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ-----RPRTRSAKKAELEENQRS 1380
Query: 1371 PQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEE 1430
++ + R + ++V + K N EE ++ +EE EEE
Sbjct: 1381 YKQKKKR-----------RRIKVQEDSSSENKSNSEEEE------EEKEEEEEEEEEEEE 1423
Query: 1431 EVSTVNVRRRSAKRERR 1447
E N +S + R+
Sbjct: 1424 EEEDENDDSKSPGKGRK 1440
Score = 38.9 bits (89), Expect = 0.036
Identities = 45/230 (19%), Positives = 94/230 (40%), Gaps = 17/230 (7%)
Query: 1122 PGKPKTTNVLGAVNKPLSSAGKQSQTKSSRME---TVSNASSS----SNPSSPGRIKGRL 1174
PG + N + + + S K+ + + + TVS+ S + P +KGR
Sbjct: 1273 PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR- 1331
Query: 1175 DSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDL 1234
+ ++ ++ED ++ + +D R+ R KK + E +
Sbjct: 1332 NRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT-----RSAKKAELEENQRSYKQKKK 1386
Query: 1235 TKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPP 1294
+ ++ Q+ S+ E +E++ EE+ +E+ E+E++ + P KG++ +
Sbjct: 1387 RRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE--EDENDDSKSPGKGRK-KIR 1443
Query: 1295 KPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSK 1344
K L + E T K+ +++ E E E+ R+ E S +K
Sbjct: 1444 KILKDDKLRTE-TQNALKEEEERRKRIAEREREREKLREVIEIEDASPTK 1492
Score = 34.3 bits (77), Expect = 0.89
Identities = 67/357 (18%), Positives = 133/357 (37%), Gaps = 64/357 (17%)
Query: 1121 TPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMD 1180
T P T+N N+ + K S + + S+ S+ NP P ++ S +D
Sbjct: 630 TETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK-PNKLPKSKQSETVD 688
Query: 1181 HSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQE 1240
+ + D ++ + SD +++ + KT + + + + G DD K ++
Sbjct: 689 QNSDSDEMLAILKEVSRMSHSSSSD---TDINEIHTNHKT-LYDLKTQAGKDDKGKRKRK 744
Query: 1241 QKPKGSQRSRKRGHTA-------------SESDEQQWPEEKRLK---------------- 1271
GS K+G +A SES EK +K
Sbjct: 745 SSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIP 804
Query: 1272 --EDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEE 1329
+D +EDE++S KKG + K +KTS++GS + + E +
Sbjct: 805 NTKDFDSSEDEKHS--KKGMDNQGHK-----------NLKTSQEGS-------SDDAERK 844
Query: 1330 EERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKK 1389
+ER++ ++ + + K + + R P+ ++ K G+ S K
Sbjct: 845 QERETFSSAEGTVDKDTTI---MELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKV 901
Query: 1390 NVRVGRSKQAATK-----ENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRS 1441
+SK TK ++ S+ + F D+ +++ ++ + T ++ S
Sbjct: 902 AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPS 958
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 54.7 bits (130), Expect = 6e-07
Identities = 62/262 (23%), Positives = 109/262 (41%), Gaps = 40/262 (15%)
Query: 1124 KPKTTN-VLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSP-------GRIKGRLD 1175
KP T N VL + S+G ++ +KS + TV + ++P + IK L
Sbjct: 1227 KPVTENLVLSSHTGFCQSSGDEALSKSVPV-TVDDDDDDNDPENRIAKKMLLEEIKANLS 1285
Query: 1176 SSEMDHSENEDYTMSSPLPGKKSDKR-----------DDSDLVRSELEKPRGRKKT---P 1221
S E D S +++ GK++++ +SD E +KPR R +
Sbjct: 1286 SDE-DGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHK 1344
Query: 1222 VTEQEEKLGMDDLTKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQ 1281
+T + + G + TK + ++ KG R + + +SD Q E + E++ E+EDEQ
Sbjct: 1345 LTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQ----ESGVSEEVSESEDEQ 1400
Query: 1282 NSPPKKGKRGRPPKPLGGGTPKEE------------PTMKTSKKGSKKKSGPPAPEEEEE 1329
+ K+ + K++ S++ ++K EEEEE
Sbjct: 1401 RPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEE 1460
Query: 1330 EERQSGNTEQKSKSKQHRVSRR 1351
EE + N + KS K + R+
Sbjct: 1461 EEEEDENDDSKSPGKGRKKIRK 1482
Score = 44.3 bits (103), Expect = 9e-04
Identities = 93/459 (20%), Positives = 161/459 (35%), Gaps = 48/459 (10%)
Query: 1012 EQLKDVKECLWFVLEILMAKNENNSHAFIRKMVENIKQTKDAQGPDDAKMNEKLYTVCDV 1071
E+L + +E F I KN K + + K + D A+ + CD
Sbjct: 1017 EKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDS 1076
Query: 1072 AMNIIMSKSTTYSLESPKDPVLPARFFTQPDKNFSNTKNYLPPEMKSFFTPGKPKTTNVL 1131
+ + SK+ Y E + +L + D + S+T+ Y E + + K +
Sbjct: 1077 SEDK-KSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELR 1135
Query: 1132 GAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSS 1191
N LSS + +S + + SS N R + + + + S+
Sbjct: 1136 ERRN--LSSKRNTKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTST 1193
Query: 1192 P------LPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKG 1245
SD DD E + K PVTE L + T Q +
Sbjct: 1194 KRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIK-PVTEN---LVLSSHTGFCQSSGDEA 1249
Query: 1246 SQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPP---KPLGGGTP 1302
+S T + D+ PE + K+ +LE S + G P K G
Sbjct: 1250 LSKSVPV--TVDDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQN 1307
Query: 1303 KEEPTMKTSKKGSKKKSGPPAPEEEEEEERQ------------SGNTEQKSKSKQHRVSR 1350
+E P + +K +S + E ++ R E+K+K K+H+ +
Sbjct: 1308 EENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVK 1367
Query: 1351 RAQQRAESPESSAIESTQST-----------PQKGRGRPSKTP-------SPSQPKKNVR 1392
+R S E S Q + Q+ R R +K S Q KK R
Sbjct: 1368 GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRR 1427
Query: 1393 VGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEEE 1431
+ + ++++ +SEE + + ++ +EE EE+E
Sbjct: 1428 IKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDE 1466
Score = 41.6 bits (96), Expect = 0.006
Identities = 58/317 (18%), Positives = 118/317 (37%), Gaps = 48/317 (15%)
Query: 1140 SAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMDHSENEDYTMSSPLPGKKSD 1199
++ S + ++ SS P L S + D +S +P D
Sbjct: 1201 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1260
Query: 1200 KRDDSD--------LVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQEQKPKGSQRSRK 1251
DD+D ++ E++ + ++ E + G K +E +++
Sbjct: 1261 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1320
Query: 1252 RGHTASESDEQQWPEEK-RLKEDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKT 1310
+ S+S+E + P + RL L D ++ KK K PKE +K
Sbjct: 1321 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTK------------PKEHKEVK- 1367
Query: 1311 SKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQST 1370
+ + + + E+ + ++SG +E+ S+S+ + + R S + + +E Q +
Sbjct: 1368 ----GRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQ-----RPRTRSAKKAELEENQRS 1418
Query: 1371 PQKGRGRPSKTPSPSQPKKNVRVGRSKQAATKENDSSEEVDVFQGSSPVDDIPQEETEEE 1430
++ + R + ++V + K N EE ++ +EE EEE
Sbjct: 1419 YKQKKKR-----------RRIKVQEDSSSENKSNSEEEE------EEKEEEEEEEEEEEE 1461
Query: 1431 EVSTVNVRRRSAKRERR 1447
E N +S + R+
Sbjct: 1462 EEEDENDDSKSPGKGRK 1478
Score = 38.9 bits (89), Expect = 0.036
Identities = 45/230 (19%), Positives = 94/230 (40%), Gaps = 17/230 (7%)
Query: 1122 PGKPKTTNVLGAVNKPLSSAGKQSQTKSSRME---TVSNASSS----SNPSSPGRIKGRL 1174
PG + N + + + S K+ + + + TVS+ S + P +KGR
Sbjct: 1311 PGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGR- 1369
Query: 1175 DSSEMDHSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDL 1234
+ ++ ++ED ++ + +D R+ R KK + E +
Sbjct: 1370 NRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRT-----RSAKKAELEENQRSYKQKKK 1424
Query: 1235 TKLVQEQKPKGSQRSRKRGHTASESDEQQWPEEKRLKEDILENEDEQNSPPKKGKRGRPP 1294
+ ++ Q+ S+ E +E++ EE+ +E+ E+E++ + P KG++ +
Sbjct: 1425 RRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEE--EDENDDSKSPGKGRK-KIR 1481
Query: 1295 KPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEEEERQSGNTEQKSKSK 1344
K L + E T K+ +++ E E E+ R+ E S +K
Sbjct: 1482 KILKDDKLRTE-TQNALKEEEERRKRIAEREREREKLREVIEIEDASPTK 1530
Score = 34.3 bits (77), Expect = 0.89
Identities = 67/357 (18%), Positives = 133/357 (37%), Gaps = 64/357 (17%)
Query: 1121 TPGKPKTTNVLGAVNKPLSSAGKQSQTKSSRMETVSNASSSSNPSSPGRIKGRLDSSEMD 1180
T P T+N N+ + K S + + S+ S+ NP P ++ S +D
Sbjct: 668 TETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPK-PNKLPKSKQSETVD 726
Query: 1181 HSENEDYTMSSPLPGKKSDKRDDSDLVRSELEKPRGRKKTPVTEQEEKLGMDDLTKLVQE 1240
+ + D ++ + SD +++ + KT + + + + G DD K ++
Sbjct: 727 QNSDSDEMLAILKEVSRMSHSSSSD---TDINEIHTNHKT-LYDLKTQAGKDDKGKRKRK 782
Query: 1241 QKPKGSQRSRKRGHTA-------------SESDEQQWPEEKRLK---------------- 1271
GS K+G +A SES EK +K
Sbjct: 783 SSTSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIP 842
Query: 1272 --EDILENEDEQNSPPKKGKRGRPPKPLGGGTPKEEPTMKTSKKGSKKKSGPPAPEEEEE 1329
+D +EDE++S KKG + K +KTS++GS + + E +
Sbjct: 843 NTKDFDSSEDEKHS--KKGMDNQGHK-----------NLKTSQEGS-------SDDAERK 882
Query: 1330 EERQSGNTEQKSKSKQHRVSRRAQQRAESPESSAIESTQSTPQKGRGRPSKTPSPSQPKK 1389
+ER++ ++ + + K + + R P+ ++ K G+ S K
Sbjct: 883 QERETFSSAEGTVDKDTTI---MELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKV 939
Query: 1390 NVRVGRSKQAATK-----ENDSSEEVDVFQGSSPVDDIPQEETEEEEVSTVNVRRRS 1441
+SK TK ++ S+ + F D+ +++ ++ + T ++ S
Sbjct: 940 AETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSEDDKKQSKKGTEEKKKPS 996
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,190,324
Number of Sequences: 37866
Number of extensions: 2718207
Number of successful extensions: 25871
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 221
Number of HSP's successfully gapped in prelim test: 1164
Number of HSP's that attempted gapping in prelim test: 16263
Number of HSP's gapped (non-prelim): 6132
length of query: 1447
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1332
effective length of database: 13,892,928
effective search space: 18505380096
effective search space used: 18505380096
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.