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Search of human proteins with 7657013
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657013 apoptosis antagonizing transcription factor [Homo
sapiens]
(560 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657013 apoptosis antagonizing transcription factor [Homo sap... 1120 0.0
gi|210032580 SET domain containing 1B [Homo sapiens] 57 3e-08
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 56 1e-07
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 53 6e-07
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 50 4e-06
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 49 9e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 48 3e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 48 3e-05
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 3e-05
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 3e-05
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 3e-05
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 3e-05
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 48 3e-05
gi|21735415 centromere protein B [Homo sapiens] 47 6e-05
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 47 6e-05
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 47 6e-05
gi|148746195 trichohyalin [Homo sapiens] 46 8e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 46 1e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 46 1e-04
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 46 1e-04
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 45 1e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 45 1e-04
gi|7705320 hepatoma-derived growth factor, related protein 3 [Ho... 45 2e-04
gi|115529449 upstream binding transcription factor, RNA polymera... 45 2e-04
gi|115529451 upstream binding transcription factor, RNA polymera... 45 2e-04
gi|7657671 upstream binding transcription factor, RNA polymerase... 45 2e-04
gi|45827729 scribble isoform b [Homo sapiens] 45 2e-04
gi|45827731 scribble isoform a [Homo sapiens] 45 2e-04
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 45 2e-04
gi|153791492 eukaryotic translation initiation factor 3, subunit... 44 3e-04
>gi|7657013 apoptosis antagonizing transcription factor [Homo
sapiens]
Length = 560
Score = 1120 bits (2897), Expect = 0.0
Identities = 560/560 (100%), Positives = 560/560 (100%)
Query: 1 MAGPQPLALQLEQLLNPRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLA 60
MAGPQPLALQLEQLLNPRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLA
Sbjct: 1 MAGPQPLALQLEQLLNPRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLA 60
Query: 61 SASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDED 120
SASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDED
Sbjct: 61 SASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDED 120
Query: 121 DLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGM 180
DLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGM
Sbjct: 121 DLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGM 180
Query: 181 EEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEG 240
EEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEG
Sbjct: 181 EEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEG 240
Query: 241 RIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQY 300
RIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQY
Sbjct: 241 RIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQY 300
Query: 301 PDTRYLVDGTKPNAGSEEISSEDDELVEEKKQQRRRVPAKRKLEMEDYPSFMAKRFADFT 360
PDTRYLVDGTKPNAGSEEISSEDDELVEEKKQQRRRVPAKRKLEMEDYPSFMAKRFADFT
Sbjct: 301 PDTRYLVDGTKPNAGSEEISSEDDELVEEKKQQRRRVPAKRKLEMEDYPSFMAKRFADFT 360
Query: 361 VYRNRTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVL 420
VYRNRTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVL
Sbjct: 361 VYRNRTLQKWHDKTKLASGKLGKGFGAFERSILTQIDHILMDKERLLRRTQTKRSVYRVL 420
Query: 421 GKPEPAAQPVPESLPGEPEILPQAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLD 480
GKPEPAAQPVPESLPGEPEILPQAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLD
Sbjct: 421 GKPEPAAQPVPESLPGEPEILPQAPANAHLKDLDEEIFDDDDFYHQLLRELIERKTSSLD 480
Query: 481 PNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTTMNDDAR 540
PNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTTMNDDAR
Sbjct: 481 PNDQVAMGRQWLAIQKLRSKIHKKVDRKASKGRKLRFHVLSKLLSFMAPIDHTTMNDDAR 540
Query: 541 TELYRSLFGQLHPPDEGHGD 560
TELYRSLFGQLHPPDEGHGD
Sbjct: 541 TELYRSLFGQLHPPDEGHGD 560
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 57.4 bits (137), Expect = 3e-08
Identities = 57/195 (29%), Positives = 89/195 (45%), Gaps = 11/195 (5%)
Query: 18 RPSEADPEADPEEATAARVIDRFDEG-EDGEGDFLVVGSIRKLASASLLDTDKRYCGKTT 76
RPS + E D EE+ R D D E + D VG R+ A LD+ G+
Sbjct: 982 RPSTSVDEED-EESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSG----GEED 1036
Query: 77 SRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDD--LGAAEEQECGDHR 134
+++ +E+ E T EE +EE D+DS+ E D++D L A E++ GD
Sbjct: 1037 EKESLSEEQ-ESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSD 1095
Query: 135 ESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESE 194
E + ++K S S+ +F + SS E+E+E EE ++ E+ + +E
Sbjct: 1096 EEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAE 1155
Query: 195 ED--RAGDRNSEDDG 207
E AG + E DG
Sbjct: 1156 ESMASAGPEDFEQDG 1170
Score = 34.7 bits (78), Expect = 0.24
Identities = 29/125 (23%), Positives = 48/125 (38%), Gaps = 12/125 (9%)
Query: 93 SSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQ 152
S DEE + E D D E D G + E K +
Sbjct: 986 SVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRPARPLELDSGGEEDEK------E 1039
Query: 153 SISDFEKFTKGMDDLGSSEEEEDEESG------MEEGDDAEDSQGESEEDRAGDRNSEDD 206
S+S+ ++ T+ ++ EEEED++ E DD + + E+ E GD + E+
Sbjct: 1040 SLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEET 1099
Query: 207 GVVMT 211
++T
Sbjct: 1100 VSIVT 1104
Score = 34.7 bits (78), Expect = 0.24
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 2/106 (1%)
Query: 21 EADPEADPEEATAARVIDRFDEGEDGEGDFL-VVGSIRKLASASLLDTDKRYCGKTTSRK 79
+ D + +E TA DEG+ E + + +V S + S+S + + S
Sbjct: 1070 DRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSP 1129
Query: 80 AWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAA 125
+ +ED E+ + +EE +EE +E G E++++D AA
Sbjct: 1130 SSSEDE-EEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAA 1174
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/175 (27%), Positives = 74/175 (42%), Gaps = 24/175 (13%)
Query: 41 DEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISD 100
+EGE+GEG+ + + G+ + E E+ G +EE +
Sbjct: 869 EEGEEGEGE----------GEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918
Query: 101 EEGSGD-EDSEGLGLEEYDE----DDLGAAEEQEC---GDHRESKKSRSHSAKTPGFSVQ 152
+G + E+ EG G EE E D G EE+E G+ E + + G +
Sbjct: 919 GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGE 978
Query: 153 SISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDG 207
+ E + G EEEE EE G EEG+ E+ +GE EE+ G+ E +G
Sbjct: 979 GEGEEE------EGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEG 1027
Score = 55.1 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 80/180 (44%), Gaps = 29/180 (16%)
Query: 41 DEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISD 100
+EGE+GEG+ ++ G+ + E E+ G +EE +
Sbjct: 860 EEGEEGEGE------------------EEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 901
Query: 101 ----EEGSGD---EDSEGLGLEEYDEDDLGAAEEQECGDHRESK-KSRSHSAKTPGFSVQ 152
EEG G+ E+ EG G EE +E + EE+ G+ + + + + G +
Sbjct: 902 GEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Query: 153 SISDFEKFTKGMDDLGSSEEEEDEESGM---EEGDDAEDSQGESEEDRAGDRNSEDDGVV 209
+ E+ +G + G E EE+E G EEG++ + +GE EE+ G+ E++G V
Sbjct: 962 GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021
Score = 48.9 bits (115), Expect = 1e-05
Identities = 45/188 (23%), Positives = 79/188 (42%), Gaps = 8/188 (4%)
Query: 21 EADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKA 80
E D EE T R ++ +EG + EG + G + + ++ G+ +
Sbjct: 790 EGDQGEGEEEETEGRGEEK-EEGGEVEGGEVEEGKGERE------EEEEEGEGEEEEGEG 842
Query: 81 WNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSR 140
E+ + G E EEG G+E+ E E +E+ G EE+ G+ E +
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902
Query: 141 SHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESE-EDRAG 199
+ G + + + +G + G EEEE E G + + E+ +GE E E+ G
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962
Query: 200 DRNSEDDG 207
+ E++G
Sbjct: 963 EGEGEEEG 970
Score = 47.0 bits (110), Expect = 5e-05
Identities = 34/119 (28%), Positives = 53/119 (44%), Gaps = 10/119 (8%)
Query: 92 GSSDEEISDEEGSGDEDSEGLGLEEY----DEDDLGAAEEQECGDHRESKKSRSHSAKTP 147
G + E + EG G+E+ EG G E +E+ G EE+E + E + +
Sbjct: 953 GEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGE 1012
Query: 148 GFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDD 206
G + + E +G + G EEEE EE G E + +GE EE+R E++
Sbjct: 1013 GEEEEE-GEVEGEVEGEEGEGEGEEEEGEEEGEE-----REKEGEGEENRRNREEEEEE 1065
Score = 46.2 bits (108), Expect = 8e-05
Identities = 46/209 (22%), Positives = 83/209 (39%), Gaps = 44/209 (21%)
Query: 34 ARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGS 93
A+ + ++G +G GD G+ + +S + + + + + ++ E PG
Sbjct: 641 AKSVGEAEDGPEGRGD----GTCEEGSSGA-----EHWQDEEREKGEKDKGRGEMERPGE 691
Query: 94 SDEEISDEEG---------------SGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKK 138
++E++++E G + +EE E++ G EE+E E +K
Sbjct: 692 GEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEK 751
Query: 139 SRSHSAKTPGFSVQSISDFE-----------KFTKGMD--DLGSSEE-------EEDEES 178
+ G V+ + E K KG + D G EE EE EE
Sbjct: 752 EGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEG 811
Query: 179 GMEEGDDAEDSQGESEEDRAGDRNSEDDG 207
G EG + E+ +GE EE+ E++G
Sbjct: 812 GEVEGGEVEEGKGEREEEEEEGEGEEEEG 840
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/116 (29%), Positives = 56/116 (48%), Gaps = 9/116 (7%)
Query: 97 EISDEEGSGD-EDSEGLGLEEY------DEDDLGAAEEQECGDHRESK-KSRSHSAKTPG 148
E +EEG G+ ED EG G EE +E+ G EE+ G+ E + + + G
Sbjct: 931 EGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEG 990
Query: 149 FSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSE 204
+ + E+ +G ++ G E EE+EE +E + E+ +GE EE+ + E
Sbjct: 991 EEEEGEEEGEEEGEGEEE-GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEE 1045
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/100 (29%), Positives = 48/100 (48%), Gaps = 11/100 (11%)
Query: 96 EEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSIS 155
EE +EEG G+E+ EG G EE + + G E +E E ++
Sbjct: 996 EEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEG-----------E 1044
Query: 156 DFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEE 195
+ EK +G ++ + EEEE+EE +E + E+ + + EE
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEE 1084
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/128 (26%), Positives = 55/128 (42%), Gaps = 13/128 (10%)
Query: 92 GSSDEEISD----EEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTP 147
G +EE D EE G+ EG G E E + E ++ + +K +
Sbjct: 736 GEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGE 795
Query: 148 GFSVQSISDFEKFTKG--------MDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAG 199
G ++ E+ +G + G EEEE+E G EE + E+ +GE EE+ G
Sbjct: 796 GEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEE-G 854
Query: 200 DRNSEDDG 207
+ E++G
Sbjct: 855 EGKGEEEG 862
Score = 39.7 bits (91), Expect = 0.007
Identities = 34/142 (23%), Positives = 58/142 (40%), Gaps = 17/142 (11%)
Query: 103 GSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTK 162
G ++ EG G +E GA Q+ + K + PG + +++ E++ K
Sbjct: 645 GEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKK 704
Query: 163 GMDDLGSSEEEED----------EESGMEEGDDAEDSQG--ESEEDRAGDRNSEDDGVVM 210
+ +E E EE G EE + E+ +G E EE++ G+ E +G
Sbjct: 705 RDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEG--- 761
Query: 211 TFSSVKVSEEVEKGRAVKNQIA 232
V+ E E+G K + A
Sbjct: 762 --EEVEGEREKEEGERKKEERA 781
Score = 38.9 bits (89), Expect = 0.013
Identities = 35/117 (29%), Positives = 53/117 (45%), Gaps = 16/117 (13%)
Query: 89 TLPGSSDEEIS-DEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSR------- 140
T+ SDEE+ EE G EDS+G G+EE + + A E+ H K+
Sbjct: 575 TIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVE----ANEENVKVHGGRKEKTEILSDDL 630
Query: 141 SHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDR 197
+ A+ +S+ + E +G D G+ EE SG E D E +GE ++ R
Sbjct: 631 TDKAEVSEGKAKSVGEAEDGPEGRGD-GTCEE---GSSGAEHWQDEEREKGEKDKGR 683
Score = 38.1 bits (87), Expect = 0.022
Identities = 30/130 (23%), Positives = 54/130 (41%), Gaps = 9/130 (6%)
Query: 87 EQTLPGSSDEEISDEEGSGDEDS------EGLGLEEYDEDDLGAAEEQECGDHRESKKSR 140
E+ G +EE + EG G+E+ +G G E +E + EE+ G+ E +
Sbjct: 914 EEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGE 973
Query: 141 SHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAE---DSQGESEEDR 197
+ G + + E+ + E EE+ E EE ++ E + +GE E
Sbjct: 974 GEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGE 1033
Query: 198 AGDRNSEDDG 207
+ E++G
Sbjct: 1034 GEEEEGEEEG 1043
Score = 29.6 bits (65), Expect = 7.7
Identities = 25/99 (25%), Positives = 44/99 (44%), Gaps = 17/99 (17%)
Query: 107 EDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDD 166
E ++ L E D+ D E +E + +E K + H ++ F Q + E F+
Sbjct: 531 ELTQDTALTENDDSD----EYEEMSEMKEGKACKQHVSQGI-FMTQPATTIEAFS----- 580
Query: 167 LGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSED 205
++E EE + AEDS+G E++ + N E+
Sbjct: 581 -------DEEVEIPEEKEGAEDSKGNGIEEQEVEANEEN 612
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 53.1 bits (126), Expect = 6e-07
Identities = 48/184 (26%), Positives = 80/184 (43%), Gaps = 27/184 (14%)
Query: 27 DPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHW 86
+ +EA AA V + ++ ++ E D + +K GK + ED
Sbjct: 114 EKKEAVAAEVKNEEEDQKEDEED---------------QNEEKGEAGKEDKDEKGEEDGK 158
Query: 87 EQTLPGSSDEEISD-EEGSGDEDSEGLGLE--EYDEDDLGAAEEQECGDHRESKKSRSHS 143
E E+ + E+G ED +G G + E ED+ + +E GD +E++ +
Sbjct: 159 EDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKG 218
Query: 144 AKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNS 203
K G V+ D ++ G +D G +E EE+G E+ D E+ +G+ E D
Sbjct: 219 DKKEGKDVKVKEDEKEREDGKEDEGGNE----EEAGKEKEDLKEEEEGKEE-----DEIK 269
Query: 204 EDDG 207
EDDG
Sbjct: 270 EDDG 273
Score = 37.4 bits (85), Expect = 0.037
Identities = 44/210 (20%), Positives = 74/210 (35%), Gaps = 21/210 (10%)
Query: 4 PQPLALQLEQLLNPRPSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASAS 63
P+ + +L +L P E P+ D +E D ++ + +
Sbjct: 16 PKRRSARLSAMLVPVTPEVKPKRTSSSRKMKTKSDMMEENIDTSAQ-----AVAETKQEA 70
Query: 64 LLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLE--EYDEDD 121
+++ D K K E+ + +E I D G E E + E +ED
Sbjct: 71 VVEEDYNENAKNGEAKITEAPASEKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQ 130
Query: 122 LGAAEEQ-----ECG--DHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGS----- 169
E+Q E G D E + K + + E KG D G+
Sbjct: 131 KEDEEDQNEEKGEAGKEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGK 190
Query: 170 --SEEEEDEESGMEEGDDAEDSQGESEEDR 197
E+E++EE E GD E+ G+ + D+
Sbjct: 191 EKGEDEKEEEDRKETGDGKENEDGKEKGDK 220
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/144 (23%), Positives = 69/144 (47%), Gaps = 14/144 (9%)
Query: 92 GSSDEEISDE---EGSGDEDSEGLGLEEYDEDDLGAAEEQECGD----HRESKKSRSHSA 144
G ++E+ E EG G+ +++G G E DE++ + E D H E + + +
Sbjct: 767 GETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826
Query: 145 KTPG--FSVQSISDFEKFTKGMDDLGSS-----EEEEDEESGMEEGDDAEDSQGESEEDR 197
+T S ++ + + KG++D G S EEEE+EE EE ++ E+ + E EE+
Sbjct: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEE 886
Query: 198 AGDRNSEDDGVVMTFSSVKVSEEV 221
+ ++ + + + + + +
Sbjct: 887 EEEEKGNEEPLSLDWPETRQKQAI 910
Score = 32.0 bits (71), Expect = 1.5
Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 14/105 (13%)
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSI------SDFEKFTKGMDDLG 168
+E +E+ L + ESK AK P +V D ++ G +D+
Sbjct: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
Query: 169 SSEE------EEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDG 207
+E EE E +G EG+ E S GE++ + G+ ++ G
Sbjct: 749 EAESTGEMPGEEGETAG--EGETEEKSGGETQPEGEGETETQGKG 791
Score = 30.0 bits (66), Expect = 5.9
Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 4/119 (3%)
Query: 21 EADPEADPEEATAARVIDRFDEGE-DGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRK 79
E PE + E T + + DE E +G+GD A + ++ G+T S++
Sbjct: 776 ETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNE---GETESQE 832
Query: 80 AWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKK 138
E+H E E+ +G E+ E E+ +E++ EE+E + E +K
Sbjct: 833 LSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEK 891
Score = 29.6 bits (65), Expect = 7.7
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 11/115 (9%)
Query: 91 PGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFS 150
PG E++++ E +G+ E E + G EE+ G E++ +T G
Sbjct: 741 PGGQ-EDVAEAESTGEMPGE-----EGETAGEGETEEKSGG---ETQPEGEGETETQGKG 791
Query: 151 VQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAE-DSQGESEEDRAGDRNSE 204
+ + E KG D+ G E E E G +G++ E +SQ S E+ +N E
Sbjct: 792 EECEDENEAEGKG-DNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDE 845
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 49.3 bits (116), Expect = 9e-06
Identities = 42/195 (21%), Positives = 78/195 (40%), Gaps = 28/195 (14%)
Query: 19 PSEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSR 78
P EA+ + + + T V D + E D +V+ ++ S+ + +
Sbjct: 2296 PGEAEVQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQPEVLSSQEMQVENEL------- 2348
Query: 79 KAWNEDHWEQTLP---GSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRE 135
ED ++ L GS + I DE E + ++E +
Sbjct: 2349 ----EDLIDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAPSN--------------L 2390
Query: 136 SKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEE 195
S+ S + + ++ D E+ T+ D GS+E+E+D + EE ++ E+ E +E
Sbjct: 2391 SQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDE 2450
Query: 196 DRAGDRNSEDDGVVM 210
GD + +DDG M
Sbjct: 2451 GEEGDEDDDDDGSEM 2465
Score = 32.7 bits (73), Expect = 0.90
Identities = 40/137 (29%), Positives = 55/137 (40%), Gaps = 15/137 (10%)
Query: 4 PQPLALQLEQLLNPRPSEADP--EADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLAS 61
P+ L+ Q Q+ N D E D + ++ R E E E D L+ + L+
Sbjct: 2334 PEVLSSQEMQVENELEDLIDELLERDGGSGNSTIIVSRSGEDESQE-DVLMDEAPSNLSQ 2392
Query: 62 ASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSS-------DEEISDEEGSGD--EDSEGL 112
AS L ++ + E E+ GS+ DEE +EE D ED EG
Sbjct: 2393 ASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEG- 2451
Query: 113 GLEEYDEDDLGAAEEQE 129
EE DEDD E E
Sbjct: 2452 --EEGDEDDDDDGSEME 2466
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 126 EEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDL------GSSEEEEDEESG 179
E E GD R+ K + +Q ISD E+ T + GS EEEE+EE
Sbjct: 229 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 288
Query: 180 MEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
EEG +E+S+ E EE+ + E+ G +S + +EEV +
Sbjct: 289 EEEGSTSEESEEEEEEE---EEEEEETGSNSEEASEQSAEEVSE 329
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 85 HWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSA 144
HW ++ P E E G G + + E+ +E DL + + R++ + S SA
Sbjct: 218 HWSRSPPRPPRERF--ELGDGRKPVKE---EKMEERDLLSDLQDISDSERKTSSAESSSA 272
Query: 145 KT-PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEE-GDDAEDSQGESEEDRAGDRN 202
++ G + + E+ +G S EEEE+EE EE G ++E++ +S E+ + +
Sbjct: 273 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 332
Query: 203 SEDD 206
SED+
Sbjct: 333 SEDE 336
Score = 37.7 bits (86), Expect = 0.028
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDH 133
KT+S ++ + + + +EE +EEGS E+SE EE +E++ EE+E G +
Sbjct: 263 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE----EEEEEEE---EEEEETGSN 315
Query: 134 RESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE 192
E +S S + +S+ E+ L E D +SG E ++AE+ GE
Sbjct: 316 SEEASEQS----AEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGE 368
Score = 37.4 bits (85), Expect = 0.037
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 55 SIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGL 114
S RK +SA ++ G + + E+ E+ S + E +EE +E+ G
Sbjct: 260 SERKTSSA---ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 316
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE 174
EE E E+E + E +++ +H P S F++ D G SEE E
Sbjct: 317 EEASEQSAEEVSEEEMSED-EERENENHLLVVPE------SRFDR------DSGESEEAE 363
Query: 175 DE-------ESGMEEGDDAEDS 189
+E S + EGD DS
Sbjct: 364 EEVGEGTPQSSALTEGDYVPDS 385
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 126 EEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDL------GSSEEEEDEESG 179
E E GD R+ K + +Q ISD E+ T + GS EEEE+EE
Sbjct: 239 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298
Query: 180 MEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
EEG +E+S+ E EE+ + E+ G +S + +EEV +
Sbjct: 299 EEEGSTSEESEEEEEEE---EEEEEETGSNSEEASEQSAEEVSE 339
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 85 HWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSA 144
HW ++ P E E G G + + E+ +E DL + + R++ + S SA
Sbjct: 228 HWSRSPPRPPRERF--ELGDGRKPVKE---EKMEERDLLSDLQDISDSERKTSSAESSSA 282
Query: 145 KT-PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEE-GDDAEDSQGESEEDRAGDRN 202
++ G + + E+ +G S EEEE+EE EE G ++E++ +S E+ + +
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
Query: 203 SEDD 206
SED+
Sbjct: 343 SEDE 346
Score = 37.7 bits (86), Expect = 0.028
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDH 133
KT+S ++ + + + +EE +EEGS E+SE EE +E++ EE+E G +
Sbjct: 273 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE----EEEEEEE---EEEEETGSN 325
Query: 134 RESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE 192
E +S S + +S+ E+ L E D +SG E ++AE+ GE
Sbjct: 326 SEEASEQS----AEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGE 378
Score = 37.4 bits (85), Expect = 0.037
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 55 SIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGL 114
S RK +SA ++ G + + E+ E+ S + E +EE +E+ G
Sbjct: 270 SERKTSSA---ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE 174
EE E E+E + E +++ +H P S F++ D G SEE E
Sbjct: 327 EEASEQSAEEVSEEEMSED-EERENENHLLVVPE------SRFDR------DSGESEEAE 373
Query: 175 DE-------ESGMEEGDDAEDS 189
+E S + EGD DS
Sbjct: 374 EEVGEGTPQSSALTEGDYVPDS 395
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 126 EEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDL------GSSEEEEDEESG 179
E E GD R+ K + +Q ISD E+ T + GS EEEE+EE
Sbjct: 230 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 289
Query: 180 MEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
EEG +E+S+ E EE+ + E+ G +S + +EEV +
Sbjct: 290 EEEGSTSEESEEEEEEE---EEEEEETGSNSEEASEQSAEEVSE 330
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 85 HWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSA 144
HW ++ P E E G G + + E+ +E DL + + R++ + S SA
Sbjct: 219 HWSRSPPRPPRERF--ELGDGRKPVKE---EKMEERDLLSDLQDISDSERKTSSAESSSA 273
Query: 145 KT-PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEE-GDDAEDSQGESEEDRAGDRN 202
++ G + + E+ +G S EEEE+EE EE G ++E++ +S E+ + +
Sbjct: 274 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 333
Query: 203 SEDD 206
SED+
Sbjct: 334 SEDE 337
Score = 37.7 bits (86), Expect = 0.028
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDH 133
KT+S ++ + + + +EE +EEGS E+SE EE +E++ EE+E G +
Sbjct: 264 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE----EEEEEEE---EEEEETGSN 316
Query: 134 RESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE 192
E +S S + +S+ E+ L E D +SG E ++AE+ GE
Sbjct: 317 SEEASEQS----AEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGE 369
Score = 37.4 bits (85), Expect = 0.037
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 55 SIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGL 114
S RK +SA ++ G + + E+ E+ S + E +EE +E+ G
Sbjct: 261 SERKTSSA---ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 317
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE 174
EE E E+E + E +++ +H P S F++ D G SEE E
Sbjct: 318 EEASEQSAEEVSEEEMSED-EERENENHLLVVPE------SRFDR------DSGESEEAE 364
Query: 175 DE-------ESGMEEGDDAEDS 189
+E S + EGD DS
Sbjct: 365 EEVGEGTPQSSALTEGDYVPDS 386
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 126 EEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDL------GSSEEEEDEESG 179
E E GD R+ K + +Q ISD E+ T + GS EEEE+EE
Sbjct: 239 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 298
Query: 180 MEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
EEG +E+S+ E EE+ + E+ G +S + +EEV +
Sbjct: 299 EEEGSTSEESEEEEEEE---EEEEEETGSNSEEASEQSAEEVSE 339
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 85 HWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSA 144
HW ++ P E E G G + + E+ +E DL + + R++ + S SA
Sbjct: 228 HWSRSPPRPPRERF--ELGDGRKPVKE---EKMEERDLLSDLQDISDSERKTSSAESSSA 282
Query: 145 KT-PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEE-GDDAEDSQGESEEDRAGDRN 202
++ G + + E+ +G S EEEE+EE EE G ++E++ +S E+ + +
Sbjct: 283 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 342
Query: 203 SEDD 206
SED+
Sbjct: 343 SEDE 346
Score = 37.7 bits (86), Expect = 0.028
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDH 133
KT+S ++ + + + +EE +EEGS E+SE EE +E++ EE+E G +
Sbjct: 273 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE----EEEEEEE---EEEEETGSN 325
Query: 134 RESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE 192
E +S S + +S+ E+ L E D +SG E ++AE+ GE
Sbjct: 326 SEEASEQS----AEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGE 378
Score = 37.4 bits (85), Expect = 0.037
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 55 SIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGL 114
S RK +SA ++ G + + E+ E+ S + E +EE +E+ G
Sbjct: 270 SERKTSSA---ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE 174
EE E E+E + E +++ +H P S F++ D G SEE E
Sbjct: 327 EEASEQSAEEVSEEEMSED-EERENENHLLVVPE------SRFDR------DSGESEEAE 373
Query: 175 DE-------ESGMEEGDDAEDS 189
+E S + EGD DS
Sbjct: 374 EEVGEGTPQSSALTEGDYVPDS 395
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 126 EEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDL------GSSEEEEDEESG 179
E E GD R+ K + +Q ISD E+ T + GS EEEE+EE
Sbjct: 207 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 266
Query: 180 MEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
EEG +E+S+ E EE+ + E+ G +S + +EEV +
Sbjct: 267 EEEGSTSEESEEEEEEE---EEEEEETGSNSEEASEQSAEEVSE 307
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 85 HWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSA 144
HW ++ P E E G G + + E+ +E DL + + R++ + S SA
Sbjct: 196 HWSRSPPRPPRERF--ELGDGRKPVKE---EKMEERDLLSDLQDISDSERKTSSAESSSA 250
Query: 145 KT-PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEE-GDDAEDSQGESEEDRAGDRN 202
++ G + + E+ +G S EEEE+EE EE G ++E++ +S E+ + +
Sbjct: 251 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 310
Query: 203 SEDD 206
SED+
Sbjct: 311 SEDE 314
Score = 37.7 bits (86), Expect = 0.028
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDH 133
KT+S ++ + + + +EE +EEGS E+SE EE +E++ EE+E G +
Sbjct: 241 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE----EEEEEEE---EEEEETGSN 293
Query: 134 RESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE 192
E +S S + +S+ E+ L E D +SG E ++AE+ GE
Sbjct: 294 SEEASEQS----AEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGE 346
Score = 37.4 bits (85), Expect = 0.037
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 55 SIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGL 114
S RK +SA ++ G + + E+ E+ S + E +EE +E+ G
Sbjct: 238 SERKTSSA---ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 294
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE 174
EE E E+E + E +++ +H P S F++ D G SEE E
Sbjct: 295 EEASEQSAEEVSEEEMSED-EERENENHLLVVPE------SRFDR------DSGESEEAE 341
Query: 175 DE-------ESGMEEGDDAEDS 189
+E S + EGD DS
Sbjct: 342 EEVGEGTPQSSALTEGDYVPDS 363
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 126 EEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDL------GSSEEEEDEESG 179
E E GD R+ K + +Q ISD E+ T + GS EEEE+EE
Sbjct: 196 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 255
Query: 180 MEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
EEG +E+S+ E EE+ + E+ G +S + +EEV +
Sbjct: 256 EEEGSTSEESEEEEEEE---EEEEEETGSNSEEASEQSAEEVSE 296
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 85 HWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSA 144
HW ++ P E E G G + + E+ +E DL + + R++ + S SA
Sbjct: 185 HWSRSPPRPPRERF--ELGDGRKPVKE---EKMEERDLLSDLQDISDSERKTSSAESSSA 239
Query: 145 KT-PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEE-GDDAEDSQGESEEDRAGDRN 202
++ G + + E+ +G S EEEE+EE EE G ++E++ +S E+ + +
Sbjct: 240 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 299
Query: 203 SEDD 206
SED+
Sbjct: 300 SEDE 303
Score = 37.7 bits (86), Expect = 0.028
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDH 133
KT+S ++ + + + +EE +EEGS E+SE EE +E++ EE+E G +
Sbjct: 230 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE----EEEEEEE---EEEEETGSN 282
Query: 134 RESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE 192
E +S S + +S+ E+ L E D +SG E ++AE+ GE
Sbjct: 283 SEEASEQS----AEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGE 335
Score = 37.4 bits (85), Expect = 0.037
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 55 SIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGL 114
S RK +SA ++ G + + E+ E+ S + E +EE +E+ G
Sbjct: 227 SERKTSSA---ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 283
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE 174
EE E E+E + E +++ +H P S F++ D G SEE E
Sbjct: 284 EEASEQSAEEVSEEEMSED-EERENENHLLVVPE------SRFDR------DSGESEEAE 330
Query: 175 DE-------ESGMEEGDDAEDS 189
+E S + EGD DS
Sbjct: 331 EEVGEGTPQSSALTEGDYVPDS 352
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 47.8 bits (112), Expect = 3e-05
Identities = 34/104 (32%), Positives = 50/104 (48%), Gaps = 9/104 (8%)
Query: 126 EEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDL------GSSEEEEDEESG 179
E E GD R+ K + +Q ISD E+ T + GS EEEE+EE
Sbjct: 241 ERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEE 300
Query: 180 MEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
EEG +E+S+ E EE+ + E+ G +S + +EEV +
Sbjct: 301 EEEGSTSEESEEEEEEE---EEEEEETGSNSEEASEQSAEEVSE 341
Score = 40.8 bits (94), Expect = 0.003
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 85 HWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSA 144
HW ++ P E E G G + + E+ +E DL + + R++ + S SA
Sbjct: 230 HWSRSPPRPPRERF--ELGDGRKPVKE---EKMEERDLLSDLQDISDSERKTSSAESSSA 284
Query: 145 KT-PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEE-GDDAEDSQGESEEDRAGDRN 202
++ G + + E+ +G S EEEE+EE EE G ++E++ +S E+ + +
Sbjct: 285 ESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEM 344
Query: 203 SEDD 206
SED+
Sbjct: 345 SEDE 348
Score = 37.7 bits (86), Expect = 0.028
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 13/119 (10%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDH 133
KT+S ++ + + + +EE +EEGS E+SE EE +E++ EE+E G +
Sbjct: 275 KTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESE----EEEEEEE---EEEEETGSN 327
Query: 134 RESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE 192
E +S S + +S+ E+ L E D +SG E ++AE+ GE
Sbjct: 328 SEEASEQS----AEEVSEEEMSEDEERENENHLLVVPESRFDRDSG--ESEEAEEEVGE 380
Score = 37.4 bits (85), Expect = 0.037
Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 23/142 (16%)
Query: 55 SIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGL 114
S RK +SA ++ G + + E+ E+ S + E +EE +E+ G
Sbjct: 272 SERKTSSA---ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 328
Query: 115 EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE 174
EE E E+E + E +++ +H P S F++ D G SEE E
Sbjct: 329 EEASEQSAEEVSEEEMSED-EERENENHLLVVPE------SRFDR------DSGESEEAE 375
Query: 175 DE-------ESGMEEGDDAEDS 189
+E S + EGD DS
Sbjct: 376 EEVGEGTPQSSALTEGDYVPDS 397
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 46.6 bits (109), Expect = 6e-05
Identities = 41/143 (28%), Positives = 65/143 (45%), Gaps = 22/143 (15%)
Query: 75 TTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDE----DDLGAAEEQEC 130
TTS K+ E+ E+ +EE +EEG G+E+ E G EE +E ++LG EE E
Sbjct: 398 TTSLKSEGEEEEEE------EEEEEEEEGEGEEEEEE-GEEEEEEGGEGEELGEEEEVEE 450
Query: 131 GDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSS-------EEEEDEESGMEEG 183
+S + ++ +++ E + +G+ + G S EE + EG
Sbjct: 451 EGDVDSDEEEEEDEESSSEGLEA----EDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEG 506
Query: 184 DDAEDSQGESEEDRAGDRNSEDD 206
+ DS E E+D D EDD
Sbjct: 507 GEDSDSDSEEEDDEEEDDEDEDD 529
Score = 46.6 bits (109), Expect = 6e-05
Identities = 33/116 (28%), Positives = 54/116 (46%), Gaps = 7/116 (6%)
Query: 83 EDHWEQTLPGSSDEEISDEEG---SGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKS 139
E+ E+ G EE+ +EE GD DS+ EE +ED+ ++E E D +
Sbjct: 427 EEGEEEEEEGGEGEELGEEEEVEEEGDVDSD----EEEEEDEESSSEGLEAEDWAQGVVE 482
Query: 140 RSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEE 195
S G ++ F +G +D S EEED+E +E +D +D + + +E
Sbjct: 483 AGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 46.6 bits (109), Expect = 6e-05
Identities = 51/210 (24%), Positives = 95/210 (45%), Gaps = 30/210 (14%)
Query: 91 PGSSDEEISD-EEGSGDEDSEGLGL-EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPG 148
P +S E +++ ++GSG E+ L +E L E + GD ++K ++ + K+P
Sbjct: 394 PQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPE 453
Query: 149 FSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSE-DDG 207
VQ + ++EE ++ E M+EG E+++G E+D+ D+ E +
Sbjct: 454 DKVQ--------------IAANEETQEREEQMKEG---EETEGSEEDDKENDKTEEMPND 496
Query: 208 VVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKG 267
V+ S++ +EE E G N WD L L K + + + ++
Sbjct: 497 SVLENKSLQENEEEEIG----NLELAWDML-----DLAKIIFKRQETKEAQLYAAQAHLK 547
Query: 268 GPEFSSALKNSHKALKALLRSLVGLQEELL 297
E S +N +A++ +S + LQE+ L
Sbjct: 548 LGEVSVESENYVQAVEE-FQSCLNLQEQYL 576
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 46.6 bits (109), Expect = 6e-05
Identities = 51/210 (24%), Positives = 95/210 (45%), Gaps = 30/210 (14%)
Query: 91 PGSSDEEISD-EEGSGDEDSEGLGL-EEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPG 148
P +S E +++ ++GSG E+ L +E L E + GD ++K ++ + K+P
Sbjct: 396 PQTSIERLTETKDGSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPE 455
Query: 149 FSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSE-DDG 207
VQ + ++EE ++ E M+EG E+++G E+D+ D+ E +
Sbjct: 456 DKVQ--------------IAANEETQEREEQMKEG---EETEGSEEDDKENDKTEEMPND 498
Query: 208 VVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKG 267
V+ S++ +EE E G N WD L L K + + + ++
Sbjct: 499 SVLENKSLQENEEEEIG----NLELAWDML-----DLAKIIFKRQETKEAQLYAAQAHLK 549
Query: 268 GPEFSSALKNSHKALKALLRSLVGLQEELL 297
E S +N +A++ +S + LQE+ L
Sbjct: 550 LGEVSVESENYVQAVEE-FQSCLNLQEQYL 578
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 46.2 bits (108), Expect = 8e-05
Identities = 77/379 (20%), Positives = 157/379 (41%), Gaps = 54/379 (14%)
Query: 114 LEEYDEDDLGAAE----EQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGS 169
L E E L A E EQ E K+ R + +Q + + E+ +
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRE----R 845
Query: 170 SEEEEDEESGMEEGDDAEDSQGES---------EEDRAGDRNSEDDGVVMTFSSVKVSEE 220
+++ ++EE G++E + SQ + EE+R R++ ++ + E+
Sbjct: 846 AQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT-------LYAKPALQEQ 898
Query: 221 VEKGRAV----KNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSALK 276
+ K + + + ++ ++ R + ++ QL Q + L +++ +
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEE-QLLREEREKRRRQERE 957
Query: 277 NSHKALKALLRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSEDDELVEEKKQQRRR 336
++ K L + +E+LL + P+ R + K EE+ E+++L+ E++++RRR
Sbjct: 958 RQYRKDKKLQQK----EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 337 VPAKRKLEMEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKGFGAFERSILTQI 396
+R+ +D + + L++ +K +L + E L Q
Sbjct: 1014 QEWERQYRKKD----------ELQQEEEQLLREEREKRRLQERERQYR----EEEELQQE 1059
Query: 397 DHILMDKERLLRRTQTKRSVYRVLGKPEPAAQPVPESLPGEPEILPQAPANAHLKDLDEE 456
+ L+ +ER RR Q YR K E Q + L EPE + ++ +EE
Sbjct: 1060 EEQLLGEERETRRRQELERQYR---KEEELQQEEEQLLREEPEKRRRQERERQCRE-EEE 1115
Query: 457 IFDDDDFYHQLLRELIERK 475
+ +++ QLLRE E++
Sbjct: 1116 LQQEEE---QLLREEREKR 1131
Score = 35.4 bits (80), Expect = 0.14
Identities = 52/265 (19%), Positives = 106/265 (40%), Gaps = 26/265 (9%)
Query: 87 EQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKT 146
EQ L +EE+ EE E + +E+ L EEQ + RE ++ +
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQ-ERQYREEEQLQQEEEQLLREEREKRRRQERER-- 958
Query: 147 PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESE----EDRAGDRN 202
Q D + K LG E+ + ++ + E+ Q E E E+R R
Sbjct: 959 -----QYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 203 SEDDGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPL 262
E + ++ EE L ++ + R++ ++ + Q + L
Sbjct: 1014 QEWERQYRKKDELQQEEEQ----------LLREEREKRRLQERERQYREEEELQQEEEQL 1063
Query: 263 FKDKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSE 322
++ L+ ++ + L + +E+LL + P+ R + + EE+ E
Sbjct: 1064 LGEERETRRRQELERQYRKEEELQQE----EEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 323 DDELVEEKKQQRRRVPAKRKLEMED 347
+++L+ E++++RRR +R+ E+
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEE 1144
Score = 31.6 bits (70), Expect = 2.0
Identities = 64/335 (19%), Positives = 132/335 (39%), Gaps = 59/335 (17%)
Query: 118 DEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEE----E 173
+E++L EEQ + RE ++ + ++E+ + D+L EE E
Sbjct: 992 EEEELQQEEEQLLREEREKRRRQ---------------EWERQYRKKDELQQEEEQLLRE 1036
Query: 174 EDEESGMEEGD----DAEDSQGESE----EDRAGDRNSEDDGVVMTFSSVKVSEEVEKGR 225
E E+ ++E + + E+ Q E E E+R R E + ++ EE
Sbjct: 1037 EREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEE----- 1091
Query: 226 AVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSALKNSHKALKAL 285
Q+ + R + ++ +L Q + L +++ L+ ++ + +
Sbjct: 1092 ----QLLREEPEKRRRQERERQCREEEELQQEEE-QLLREEREKRRRQELERQYREEEEV 1146
Query: 286 LRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSEDDELVEEKKQQRRRVPAKRKLEM 345
+ +E+LL + P+ R + + EE+ E+++L+ E++++RR+ ++ E
Sbjct: 1147 QQE----EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREE 1202
Query: 346 EDYPSFMAKRFADFTVYRNRTLQKW----------HDKTKLASGKLGKGFGAFERSIL-- 393
E+ KR + R+ KW D G+ + F E S L
Sbjct: 1203 EELQ--RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRD 1260
Query: 394 ----TQIDHILMDKERLLRRTQTKRSVYRVLGKPE 424
+ H+L +++ R + +R R PE
Sbjct: 1261 RQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Score = 30.8 bits (68), Expect = 3.4
Identities = 62/334 (18%), Positives = 116/334 (34%), Gaps = 66/334 (19%)
Query: 87 EQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKT 146
EQ L ++++ +E E L + + EEQ+ +K R
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 147 PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDA--EDSQGESEEDRAGDRNSE 204
+ + E++ K +++ E E+++ +E D E+ Q E + R+ E
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQE 1792
Query: 205 DDGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFK 264
D + E E+ R + + L Q +G+ + ++ L +
Sbjct: 1793 SD---------RKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE----------- 1832
Query: 265 DKGGPEFSSALKNSHKALKALLRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSEDD 324
QE+ L Q D +Y + + A E+ E+
Sbjct: 1833 ----------------------------QEQRLRQERDRQYRAE--EQFATQEKSRREEQ 1862
Query: 325 ELVEEKKQQRRRVPAKRKLEMEDYPSFMAKRFADFTVYRNRTLQKWHDKTKLASGKLGKG 384
EL +E++Q+RR+ +RKL E + R + ++ H + + GKG
Sbjct: 1863 ELWQEEEQKRRQ-ERERKLREEH-------------IRRQQKEEQRHRQVGEIKSQEGKG 1908
Query: 385 FGAFERSILTQIDHILMDKERLLRRTQTKRSVYR 418
G Q + + L Q +RS YR
Sbjct: 1909 HGRLLEPGTHQFASVPVRSSPLYEYIQEQRSQYR 1942
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/259 (22%), Positives = 103/259 (39%), Gaps = 53/259 (20%)
Query: 97 EISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQ--ECGDHRESKKSRSHSAKTPGFSVQSI 154
E+ +EEG +E+ G EE +E+D GA +Q E G +E
Sbjct: 519 EVKEEEGEKEEEE---GQEEEEEEDEGAKSDQAEEGGSEKE------------------- 556
Query: 155 SDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSS 214
GSSE+EE E+ E +AE + E++E++ + SE+ V T
Sbjct: 557 -------------GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE---VATKEE 600
Query: 215 VKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSA 274
+ +VEK K+ + +G+ + K+ + P+ + P S
Sbjct: 601 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 660
Query: 275 LKNSHKALKALLRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSED---------DE 325
++ K+ S ++E+ P + +K G E E+ +E
Sbjct: 661 VEEKGKSPV----SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE 716
Query: 326 LVEEKKQQRRRVPAKRKLE 344
VE+K+++ + VP K+K E
Sbjct: 717 KVEKKEEKPKDVPEKKKAE 735
Score = 36.6 bits (83), Expect = 0.063
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 28/156 (17%)
Query: 96 EEISDEEGSGDEDSEGLGLEE------------YDEDDLGAAEEQECGDHRESKKSRSHS 143
EEI +E DE SE +EE E+ AAEE+E + E+++ +
Sbjct: 454 EEIIEETKVEDEKSE---MEEALTAITEELAVSMKEEKKEAAEEKE--EEPEAEEEEVAA 508
Query: 144 AKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESE--------E 195
K+P V++ + K +G + +EEE+EE + D AE+ E E E
Sbjct: 509 KKSP---VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 565
Query: 196 DRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQI 231
G+ +E +G K EE + A K ++
Sbjct: 566 QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEEL 601
Score = 32.3 bits (72), Expect = 1.2
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 11/172 (6%)
Query: 73 GKTTSRKAWNEDHWEQTLPGSSDEEISD--EEGSGDE-DSEGLGLEEYDEDDLGAAEEQE 129
GK+ K+ E+ + +P S EE E G G++ + E ++E +++ +E++
Sbjct: 665 GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 724
Query: 130 CGDHRESKKSRSHSAKTPGFSVQSISD-----FEKFTKGMDDLGSSEEEEDE---ESGME 181
D E KK+ S + V +I+ EK TK E+E+++ E G E
Sbjct: 725 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE 784
Query: 182 EGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIAL 233
E + ++G +ED A + E V + K S E+ V N + L
Sbjct: 785 EEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDL 836
Score = 30.4 bits (67), Expect = 4.5
Identities = 27/115 (23%), Positives = 49/115 (42%), Gaps = 10/115 (8%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDE------DSEGLGLEEYDEDDLGAAEE 127
K T+ + E+ ++ G +EE DE D+ + EG +E E + G E
Sbjct: 514 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573
Query: 128 QECGDHRESKKSRSHSAKTPGFSVQS--ISD--FEKFTKGMDDLGSSEEEEDEES 178
+ G+ E+K+ + K+ + + ++D EK K + S EE +S
Sbjct: 574 EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 628
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/259 (22%), Positives = 103/259 (39%), Gaps = 53/259 (20%)
Query: 97 EISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQ--ECGDHRESKKSRSHSAKTPGFSVQSI 154
E+ +EEG +E+ G EE +E+D GA +Q E G +E
Sbjct: 143 EVKEEEGEKEEEE---GQEEEEEEDEGAKSDQAEEGGSEKE------------------- 180
Query: 155 SDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSS 214
GSSE+EE E+ E +AE + E++E++ + SE+ V T
Sbjct: 181 -------------GSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE---VATKEE 224
Query: 215 VKVSEEVEKGRAVKNQIALWDQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKGGPEFSSA 274
+ +VEK K+ + +G+ + K+ + P+ + P S
Sbjct: 225 LVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSP 284
Query: 275 LKNSHKALKALLRSLVGLQEELLFQYPDTRYLVDGTKPNAGSEEISSED---------DE 325
++ K+ S ++E+ P + +K G E E+ +E
Sbjct: 285 VEEKGKSPV----SKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEE 340
Query: 326 LVEEKKQQRRRVPAKRKLE 344
VE+K+++ + VP K+K E
Sbjct: 341 KVEKKEEKPKDVPEKKKAE 359
Score = 36.6 bits (83), Expect = 0.063
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 28/156 (17%)
Query: 96 EEISDEEGSGDEDSEGLGLEE------------YDEDDLGAAEEQECGDHRESKKSRSHS 143
EEI +E DE SE +EE E+ AAEE+E + E+++ +
Sbjct: 78 EEIIEETKVEDEKSE---MEEALTAITEELAVSMKEEKKEAAEEKE--EEPEAEEEEVAA 132
Query: 144 AKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESE--------E 195
K+P V++ + K +G + +EEE+EE + D AE+ E E E
Sbjct: 133 KKSP---VKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGE 189
Query: 196 DRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQI 231
G+ +E +G K EE + A K ++
Sbjct: 190 QEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEEL 225
Score = 32.3 bits (72), Expect = 1.2
Identities = 43/172 (25%), Positives = 75/172 (43%), Gaps = 11/172 (6%)
Query: 73 GKTTSRKAWNEDHWEQTLPGSSDEEISD--EEGSGDE-DSEGLGLEEYDEDDLGAAEEQE 129
GK+ K+ E+ + +P S EE E G G++ + E ++E +++ +E++
Sbjct: 289 GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEK 348
Query: 130 CGDHRESKKSRSHSAKTPGFSVQSISD-----FEKFTKGMDDLGSSEEEEDE---ESGME 181
D E KK+ S + V +I+ EK TK E+E+++ E G E
Sbjct: 349 PKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSE 408
Query: 182 EGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIAL 233
E + ++G +ED A + E V + K S E+ V N + L
Sbjct: 409 EEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDL 460
Score = 30.4 bits (67), Expect = 4.5
Identities = 27/115 (23%), Positives = 49/115 (42%), Gaps = 10/115 (8%)
Query: 74 KTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDE------DSEGLGLEEYDEDDLGAAEE 127
K T+ + E+ ++ G +EE DE D+ + EG +E E + G E
Sbjct: 138 KATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197
Query: 128 QECGDHRESKKSRSHSAKTPGFSVQS--ISD--FEKFTKGMDDLGSSEEEEDEES 178
+ G+ E+K+ + K+ + + ++D EK K + S EE +S
Sbjct: 198 EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKS 252
>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member B [Homo sapiens]
Length = 251
Score = 45.8 bits (107), Expect = 1e-04
Identities = 26/106 (24%), Positives = 53/106 (50%), Gaps = 5/106 (4%)
Query: 100 DEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEK 159
+++ + D D+E G++E +ED+ G EE E D + ++ V+ D ++
Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDE--DDEDGEEEEFDEEDDEDEDVEGDEDDDE 208
Query: 160 FTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSED 205
++ ++ G EE+EDE+ E+ ++ E +GE + D +D
Sbjct: 209 VSEEEEEFGLDEEDEDED---EDEEEEEGGKGEKRKRETDDEGEDD 251
Score = 35.4 bits (80), Expect = 0.14
Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 3/105 (2%)
Query: 121 DLGAAEEQECGDHRESK-KSRSHSAKTPGFSV--QSISDFEKFTKGMDDLGSSEEEEDEE 177
DL E D+RES K G+ Q D + G+D+ EE EDEE
Sbjct: 119 DLFNCEVTNLNDYRESVFKLLPQLTYLDGYDREDQEAPDSDAEVDGVDEEEEDEEGEDEE 178
Query: 178 SGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVE 222
+E + E+ E +ED + + +DD V + EE E
Sbjct: 179 DEDDEDGEEEEFDEEDDEDEDVEGDEDDDEVSEEEEEFGLDEEDE 223
Score = 33.1 bits (74), Expect = 0.69
Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 82 NEDHWEQTLPGSSDEEISDEEGSGDEDS-----EGLGLEEYDEDDLGAAEEQECGDHRES 136
+ED E+ DE+ D EG D+D E GL+E DED+ EE+E G +
Sbjct: 182 DEDGEEEEFDEEDDED-EDVEGDEDDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKR 240
Query: 137 KK 138
K+
Sbjct: 241 KR 242
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/222 (24%), Positives = 87/222 (39%), Gaps = 39/222 (17%)
Query: 39 RFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEI 98
+F++ EDG G+F S +S + C + S + + +E + EE
Sbjct: 430 KFEKTEDG-GEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEG 488
Query: 99 SDEEGSGDE-------------DSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAK 145
+ GS ++ D E GL + EDDL E+E G +ES++ S
Sbjct: 489 NPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES 548
Query: 146 TPGFSVQSISD-----FEK--FTKGMDDLGS-----------------SEEEEDEESGME 181
S + D FE+ K +D+ GS SE E E+ G E
Sbjct: 549 DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSE 608
Query: 182 EGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
+ D E S+ E +ED + ++ E+D F +E E+
Sbjct: 609 KVLDEEGSEREFDED-SDEKEEEEDTYEKVFDDESDEKEDEE 649
Score = 38.5 bits (88), Expect = 0.016
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 12/200 (6%)
Query: 20 SEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRK 79
SE + + D E + +R E E D GS ++L L DK +
Sbjct: 544 SEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVL---DKELEENDSENS 600
Query: 80 AWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKS 139
+ +D E+ L E DE+ E+ E + +D++ ++E+E ++ + K
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDE----SDEKEDEEYADEKGL 656
Query: 140 RSHSAKTP-GFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRA 198
+ K G + + + FE+ D+ +E ED + + E DD+ + + EED +
Sbjct: 657 EAADKKAEEGDADEKL--FEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSS 714
Query: 199 GD--RNSEDDGVVMTFSSVK 216
+S++ G + F SV+
Sbjct: 715 EKLFDDSDERGTLGGFGSVE 734
Score = 37.0 bits (84), Expect = 0.048
Identities = 50/207 (24%), Positives = 79/207 (38%), Gaps = 30/207 (14%)
Query: 7 LALQLEQLLNPRPSE-ADPEADPEEATAARVIDRF---DEGEDG-EGDFLVVGSIRKLAS 61
LA + E LN E P + EE + + D + EDG E +F G + L
Sbjct: 517 LAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDE 576
Query: 62 ASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDD 121
++K ++ D E++ DEEGS E E +E +ED
Sbjct: 577 EG---SEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDT 633
Query: 122 LGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEED-EESGM 180
E+ D + K+ ++ + KG++ EE D +E
Sbjct: 634 Y----EKVFDDESDEKEDEEYADE----------------KGLEAADKKAEEGDADEKLF 673
Query: 181 EEGDDAEDSQGESEE-DRAGDRNSEDD 206
EE DD ED + +E + A ++ EDD
Sbjct: 674 EESDDKEDEDADGKEVEDADEKLFEDD 700
Score = 32.3 bits (72), Expect = 1.2
Identities = 43/202 (21%), Positives = 75/202 (37%), Gaps = 35/202 (17%)
Query: 54 GSIRKL----------ASASLLDTDKR-YC----------GKTTSRKAWN--EDHWEQTL 90
G IRKL AS S D ++ YC G+ + +AW+ D+ +
Sbjct: 299 GQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEET 358
Query: 91 PGSSDEEISDEEGSGDEDSEGLGLEEYDE----DDLGAAEEQECGDHRESKKSRSHSAKT 146
+E + E + GL D + G + + +H + K + T
Sbjct: 359 SREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETAT 418
Query: 147 PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDD 206
G + + D +KF K +E+ + E G E + E S + E+ ++ SE+
Sbjct: 419 -GMAFEEPIDEKKFEK-------TEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEG 470
Query: 207 GVVMTFSSVKVSEEVEKGRAVK 228
F +E E+G V+
Sbjct: 471 CPKRGFEGSCSQKESEEGNPVR 492
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/222 (24%), Positives = 87/222 (39%), Gaps = 39/222 (17%)
Query: 39 RFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEI 98
+F++ EDG G+F S +S + C + S + + +E + EE
Sbjct: 430 KFEKTEDG-GEFEEGASENNAKESSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEG 488
Query: 99 SDEEGSGDE-------------DSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAK 145
+ GS ++ D E GL + EDDL E+E G +ES++ S
Sbjct: 489 NPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKES 548
Query: 146 TPGFSVQSISD-----FEK--FTKGMDDLGS-----------------SEEEEDEESGME 181
S + D FE+ K +D+ GS SE E E+ G E
Sbjct: 549 DEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSE 608
Query: 182 EGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEK 223
+ D E S+ E +ED + ++ E+D F +E E+
Sbjct: 609 KVLDEEGSEREFDED-SDEKEEEEDTYEKVFDDESDEKEDEE 649
Score = 38.5 bits (88), Expect = 0.016
Identities = 45/200 (22%), Positives = 85/200 (42%), Gaps = 12/200 (6%)
Query: 20 SEADPEADPEEATAARVIDRFDEGEDGEGDFLVVGSIRKLASASLLDTDKRYCGKTTSRK 79
SE + + D E + +R E E D GS ++L L DK +
Sbjct: 544 SEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKELHENVL---DKELEENDSENS 600
Query: 80 AWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKS 139
+ +D E+ L E DE+ E+ E + +D++ ++E+E ++ + K
Sbjct: 601 EFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDE----SDEKEDEEYADEKGL 656
Query: 140 RSHSAKTP-GFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRA 198
+ K G + + + FE+ D+ +E ED + + E DD+ + + EED +
Sbjct: 657 EAADKKAEEGDADEKL--FEESDDKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSS 714
Query: 199 GD--RNSEDDGVVMTFSSVK 216
+S++ G + F SV+
Sbjct: 715 EKLFDDSDERGTLGGFGSVE 734
Score = 37.0 bits (84), Expect = 0.048
Identities = 50/207 (24%), Positives = 79/207 (38%), Gaps = 30/207 (14%)
Query: 7 LALQLEQLLNPRPSE-ADPEADPEEATAARVIDRF---DEGEDG-EGDFLVVGSIRKLAS 61
LA + E LN E P + EE + + D + EDG E +F G + L
Sbjct: 517 LAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDE 576
Query: 62 ASLLDTDKRYCGKTTSRKAWNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDD 121
++K ++ D E++ DEEGS E E +E +ED
Sbjct: 577 EG---SEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDT 633
Query: 122 LGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEED-EESGM 180
E+ D + K+ ++ + KG++ EE D +E
Sbjct: 634 Y----EKVFDDESDEKEDEEYADE----------------KGLEAADKKAEEGDADEKLF 673
Query: 181 EEGDDAEDSQGESEE-DRAGDRNSEDD 206
EE DD ED + +E + A ++ EDD
Sbjct: 674 EESDDKEDEDADGKEVEDADEKLFEDD 700
Score = 32.3 bits (72), Expect = 1.2
Identities = 43/202 (21%), Positives = 75/202 (37%), Gaps = 35/202 (17%)
Query: 54 GSIRKL----------ASASLLDTDKR-YC----------GKTTSRKAWN--EDHWEQTL 90
G IRKL AS S D ++ YC G+ + +AW+ D+ +
Sbjct: 299 GQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDGRWFGGRQITAQAWDGTTDYQVEET 358
Query: 91 PGSSDEEISDEEGSGDEDSEGLGLEEYDE----DDLGAAEEQECGDHRESKKSRSHSAKT 146
+E + E + GL D + G + + +H + K + T
Sbjct: 359 SREREERLRGWEAFLNAPEANRGLRRSDSVSASERAGPSRARHFSEHPSTSKMNAQETAT 418
Query: 147 PGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDD 206
G + + D +KF K +E+ + E G E + E S + E+ ++ SE+
Sbjct: 419 -GMAFEEPIDEKKFEK-------TEDGGEFEEGASENNAKESSPEKEAEEGCPEKESEEG 470
Query: 207 GVVMTFSSVKVSEEVEKGRAVK 228
F +E E+G V+
Sbjct: 471 CPKRGFEGSCSQKESEEGNPVR 492
>gi|7705320 hepatoma-derived growth factor, related protein 3 [Homo
sapiens]
Length = 203
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 32/139 (23%)
Query: 73 GKTTSRKAWNEDHWE-QTLPG--------SSDEEISDEEGSGDEDSEGLGLEEYD---ED 120
GK+ RK +NE WE + PG + S+ EG G ++ EE D ED
Sbjct: 73 GKSNKRKGFNEGLWEIENNPGVKFTGYQAIQQQSSSETEGEGGNTADASSEEEGDRVEED 132
Query: 121 DLGAAEEQECGDHRE----SKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDE 176
G + ++ G R+ SKKS S K+PG D+ +EE+
Sbjct: 133 GKGKRKNEKAGSKRKKSYTSKKSSKQSRKSPG----------------DEDDKDCKEEEN 176
Query: 177 ESGMEEGDDAEDSQGESEE 195
+S E GD D++ + +
Sbjct: 177 KSSSEGGDAGNDTRNTTSD 195
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 112 LGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTK-GMDDLGSS 170
L ++ D A +E + K R + K+ ++QS S+ E+ + DD
Sbjct: 595 LWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDED 654
Query: 171 EEEEDEESGMEEGDDAEDSQGESEEDRA--GDRNSEDD 206
EEEED+E+G + +D DS S ED + GD N EDD
Sbjct: 655 EEEEDDENG-DSSEDGGDSSESSSEDESEDGDENEEDD 691
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 30/120 (25%)
Query: 89 TLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPG 148
TL S+ E DEE DED + E +EDD ++ GD ES
Sbjct: 633 TLQSKSESEEDDEEDEDDEDED-----EEEEDDENGDSSEDGGDSSESSSEDES------ 681
Query: 149 FSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE---SEEDRAGDRNSED 205
+D +EE++++E E+ D+ ED++ E S +GD + D
Sbjct: 682 ----------------EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 31.2 bits (69), Expect = 2.6
Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 170 SEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEE 220
SE EED+E +E D+ ED E EED +SED G SS SE+
Sbjct: 638 SESEEDDEE--DEDDEDED---EEEEDDENGDSSEDGGDSSESSSEDESED 683
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 83 EDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSH 142
E+ ++ S D S E S DE +G EE DED+ ++ E D E +S
Sbjct: 656 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE----DDDEDDDEDEDNESEGS 711
Query: 143 SAKTPGFSVQSISD 156
S+ + S SD
Sbjct: 712 SSSSSSSGDSSDSD 725
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 112 LGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTK-GMDDLGSS 170
L ++ D A +E + K R + K+ ++QS S+ E+ + DD
Sbjct: 595 LWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDED 654
Query: 171 EEEEDEESGMEEGDDAEDSQGESEEDRA--GDRNSEDD 206
EEEED+E+G + +D DS S ED + GD N EDD
Sbjct: 655 EEEEDDENG-DSSEDGGDSSESSSEDESEDGDENEEDD 691
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 30/120 (25%)
Query: 89 TLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPG 148
TL S+ E DEE DED + E +EDD ++ GD ES
Sbjct: 633 TLQSKSESEEDDEEDEDDEDED-----EEEEDDENGDSSEDGGDSSESSSEDES------ 681
Query: 149 FSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE---SEEDRAGDRNSED 205
+D +EE++++E E+ D+ ED++ E S +GD + D
Sbjct: 682 ----------------EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 725
Score = 31.2 bits (69), Expect = 2.6
Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 170 SEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEE 220
SE EED+E +E D+ ED E EED +SED G SS SE+
Sbjct: 638 SESEEDDEE--DEDDEDED---EEEEDDENGDSSEDGGDSSESSSEDESED 683
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 83 EDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSH 142
E+ ++ S D S E S DE +G EE DED+ ++ E D E +S
Sbjct: 656 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE----DDDEDDDEDEDNESEGS 711
Query: 143 SAKTPGFSVQSISD 156
S+ + S SD
Sbjct: 712 SSSSSSSGDSSDSD 725
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 45.1 bits (105), Expect = 2e-04
Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 4/98 (4%)
Query: 112 LGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSISDFEKFTK-GMDDLGSS 170
L ++ D A +E + K R + K+ ++QS S+ E+ + DD
Sbjct: 632 LWVKSLSPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQSKSESEEDDEEDEDDEDED 691
Query: 171 EEEEDEESGMEEGDDAEDSQGESEEDRA--GDRNSEDD 206
EEEED+E+G + +D DS S ED + GD N EDD
Sbjct: 692 EEEEDDENG-DSSEDGGDSSESSSEDESEDGDENEEDD 728
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/120 (25%), Positives = 48/120 (40%), Gaps = 30/120 (25%)
Query: 89 TLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPG 148
TL S+ E DEE DED + E +EDD ++ GD ES
Sbjct: 670 TLQSKSESEEDDEEDEDDEDED-----EEEEDDENGDSSEDGGDSSESSSEDES------ 718
Query: 149 FSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGE---SEEDRAGDRNSED 205
+D +EE++++E E+ D+ ED++ E S +GD + D
Sbjct: 719 ----------------EDGDENEEDDEDEDDDEDDDEDEDNESEGSSSSSSSSGDSSDSD 762
Score = 31.2 bits (69), Expect = 2.6
Identities = 22/51 (43%), Positives = 27/51 (52%), Gaps = 5/51 (9%)
Query: 170 SEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEE 220
SE EED+E +E D+ ED E EED +SED G SS SE+
Sbjct: 675 SESEEDDEE--DEDDEDED---EEEEDDENGDSSEDGGDSSESSSEDESED 720
Score = 30.0 bits (66), Expect = 5.9
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 83 EDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSH 142
E+ ++ S D S E S DE +G EE DED+ ++ E D E +S
Sbjct: 693 EEEDDENGDSSEDGGDSSESSSEDESEDGDENEEDDEDE----DDDEDDDEDEDNESEGS 748
Query: 143 SAKTPGFSVQSISD 156
S+ + S SD
Sbjct: 749 SSSSSSSGDSSDSD 762
>gi|45827729 scribble isoform b [Homo sapiens]
Length = 1630
Score = 44.7 bits (104), Expect = 2e-04
Identities = 61/245 (24%), Positives = 94/245 (38%), Gaps = 50/245 (20%)
Query: 81 WNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSR 140
W+ P + EE +EEGS E EE +E++ AEE+E E K+
Sbjct: 645 WHNGPHAPWAPRAQKEEEEEEEGSPQE-------EEEEEEEENRAEEEEASTEEEDKEGA 697
Query: 141 SHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE------------------DEESGMEE 182
SA SV+ +S F++ + + EEEE + S +
Sbjct: 698 VVSAP----SVKGVS-FDQANNLLIEPARIEEEELTLTILRQTGGLGISIAGGKGSTPYK 752
Query: 183 GDD--------AEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIALW 234
GDD +E+ R GD+ E +GV + + + E +G Q+ +W
Sbjct: 753 GDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVW 812
Query: 235 DQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKGG-------PEFSSALKNSHKALKALLR 287
E ++ + A+ T P+ D P + GG PE L+ H A L R
Sbjct: 813 ---RERMVEPENAVTITPLRPEDDYSPRERRGGGLRLPLLPPESPGPLRQRHVA--CLAR 867
Query: 288 SLVGL 292
S GL
Sbjct: 868 SERGL 872
>gi|45827731 scribble isoform a [Homo sapiens]
Length = 1655
Score = 44.7 bits (104), Expect = 2e-04
Identities = 61/245 (24%), Positives = 94/245 (38%), Gaps = 50/245 (20%)
Query: 81 WNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSR 140
W+ P + EE +EEGS E EE +E++ AEE+E E K+
Sbjct: 645 WHNGPHAPWAPRAQKEEEEEEEGSPQE-------EEEEEEEENRAEEEEASTEEEDKEGA 697
Query: 141 SHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEE------------------DEESGMEE 182
SA SV+ +S F++ + + EEEE + S +
Sbjct: 698 VVSAP----SVKGVS-FDQANNLLIEPARIEEEELTLTILRQTGGLGISIAGGKGSTPYK 752
Query: 183 GDD--------AEDSQGESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVKNQIALW 234
GDD +E+ R GD+ E +GV + + + E +G Q+ +W
Sbjct: 753 GDDEGIFISRVSEEGPAARAGVRVGDKLLEVNGVALQGAEHHEAVEALRGAGTAVQMRVW 812
Query: 235 DQLLEGRIKLQKALLTTNQLPQPDVFPLFKDKGG-------PEFSSALKNSHKALKALLR 287
E ++ + A+ T P+ D P + GG PE L+ H A L R
Sbjct: 813 ---RERMVEPENAVTITPLRPEDDYSPRERRGGGLRLPLLPPESPGPLRQRHVA--CLAR 867
Query: 288 SLVGL 292
S GL
Sbjct: 868 SERGL 872
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 44.7 bits (104), Expect = 2e-04
Identities = 38/153 (24%), Positives = 63/153 (41%), Gaps = 43/153 (28%)
Query: 93 SSDEEISDEEGSGD----EDSEGLGLEEYDEDDLGAA---EEQECGDHRESKKSRSHSAK 145
SS +E D +G+ D E+ EG EEY ED+ EE E GD E +
Sbjct: 85 SSVDECDDSDGTEDMDEKEEDEG---EEYSEDNDEPGDEDEEDEEGDREEEE-------- 133
Query: 146 TPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDRAGDRNSED 205
E EE++E E+G+D ED + E EE+ + E+
Sbjct: 134 -------------------------EIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEEN 168
Query: 206 DGVVMTFSSVKVSEEVEKGRAVKNQIALWDQLL 238
+ M + ++ ++ EK ++ +D+L+
Sbjct: 169 EDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELV 201
Score = 40.0 bits (92), Expect = 0.006
Identities = 40/136 (29%), Positives = 65/136 (47%), Gaps = 19/136 (13%)
Query: 81 WNEDHWEQTLPGSSDEEISDEEGSGDEDSEGLGLEEYDED------DLGAAEEQECGDHR 134
++ED+ E PG DEE DEEG +E+ E +EE DED D+ EE+E +
Sbjct: 110 YSEDNDE---PGDEDEE--DEEGDREEEEE---IEEEDEDDDEDGEDVEDEEEEEEEEEE 161
Query: 135 ESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAED----SQ 190
E ++ + + + + + D EK D+ + +E +S + G AED ++
Sbjct: 162 EEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEY-DNYDELVAKSLLNLGKIAEDAAYRAR 220
Query: 191 GESEEDRAGDRNSEDD 206
ESE + + EDD
Sbjct: 221 TESEMNSNTSNSLEDD 236
Score = 35.0 bits (79), Expect = 0.18
Identities = 20/72 (27%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 135 ESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESE 194
+ K+ + + K F+V++ S D +E+E++E G E +D ++ E E
Sbjct: 64 QDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDE-GEEYSEDNDEPGDEDE 122
Query: 195 EDRAGDRNSEDD 206
ED GDR E++
Sbjct: 123 EDEEGDREEEEE 134
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 44.3 bits (103), Expect = 3e-04
Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 19/103 (18%)
Query: 96 EEISDEEGS-GDEDSEGLGLEEYDEDDLGAAEEQECGDHRESKKSRSHSAKTPGFSVQSI 154
E+ +DE+ +EDSEG E+ DED + AA + KKS + S ++
Sbjct: 164 EQSADEDAEKNEEDSEGSSDEDEDEDGVSAATFLK-------KKSEAPSGES-------- 208
Query: 155 SDFEKFTKGMDDLGSSEEEEDEESGMEEGDDAEDSQGESEEDR 197
KF K MDD E+ +++ + G + DS E EE +
Sbjct: 209 ---RKFLKKMDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGK 248
Score = 31.6 bits (70), Expect = 2.0
Identities = 26/98 (26%), Positives = 44/98 (44%), Gaps = 11/98 (11%)
Query: 132 DHRESKKSRSHSAKTPGFSVQSISDFEKFTKGMDDLGSSEEEEDEESGMEEGD-DAEDSQ 190
D KK ++AK Q I K+ + + +S ++ E+S E+ + + EDS+
Sbjct: 123 DKEGKKKMNKNNAKALSTLRQKI---RKYNRDFESHITSYKQNPEQSADEDAEKNEEDSE 179
Query: 191 GESEEDRAGDRNSEDDGVVMTFSSVKVSEEVEKGRAVK 228
G S+ED ED+ V + +K E G + K
Sbjct: 180 GSSDED-------EDEDGVSAATFLKKKSEAPSGESRK 210
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,765,809
Number of Sequences: 37866
Number of extensions: 1213515
Number of successful extensions: 13879
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 346
Number of HSP's that attempted gapping in prelim test: 7428
Number of HSP's gapped (non-prelim): 3382
length of query: 560
length of database: 18,247,518
effective HSP length: 107
effective length of query: 453
effective length of database: 14,195,856
effective search space: 6430722768
effective search space used: 6430722768
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.