Search of human proteins with 7656948

Search of human proteins with 7656948

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7656948 voltage-dependent calcium channel gamma-4 subunit
[Homo sapiens]
         (327 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Ho...   660   0.0  
gi|24586686 voltage-dependent calcium channel gamma-8 subunit [H...   379   e-105
gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Ho...   376   e-104
gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Ho...   358   3e-99
gi|22027551 voltage-dependent calcium channel gamma-5 subunit is...   125   4e-29
gi|7656950 voltage-dependent calcium channel gamma-5 subunit iso...   116   3e-26
gi|21361975 voltage-dependent calcium channel gamma-7 subunit [H...   115   4e-26
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]       56   4e-08
gi|226437592 transmembrane protein 114 [Homo sapiens]                  56   4e-08
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo...    55   1e-07
gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]           39   0.008
gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens]           39   0.008
gi|5921465 claudin 10 isoform b [Homo sapiens]                         38   0.014
gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Ho...    38   0.014
gi|33598916 claudin 10 isoform a [Homo sapiens]                        37   0.031
gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2 ...    35   0.070
gi|50345279 claudin 18 isoform 2 [Homo sapiens]                        35   0.070
gi|7656981 claudin 15 [Homo sapiens]                                   35   0.070
gi|88758580 cyclin L2 isoform A [Homo sapiens]                         35   0.091
gi|7705961 claudin 18 isoform 1 [Homo sapiens]                         35   0.091
gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]                    33   0.26 
gi|22748835 transmembrane protein 178 [Homo sapiens]                   33   0.26 
gi|157951718 GSG1-like isoform 1 [Homo sapiens]                        33   0.35 
gi|22027554 voltage-dependent calcium channel gamma-6 subunit is...    32   0.59 
gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]       32   0.77 
gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens]             32   0.77 
gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]              32   0.77 
gi|21389571 GSG1-like isoform 2 [Homo sapiens]                         32   0.77 
gi|4502877 claudin 4 [Homo sapiens]                                    32   1.0  
gi|22027560 voltage-dependent calcium channel gamma-6 subunit is...    31   1.3  

>gi|7656948 voltage-dependent calcium channel gamma-4 subunit [Homo
           sapiens]
          Length = 327

 Score =  660 bits (1702), Expect = 0.0
 Identities = 327/327 (100%), Positives = 327/327 (100%)

Query: 1   MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
           MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD
Sbjct: 1   MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60

Query: 61  LTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLL 120
           LTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLL
Sbjct: 61  LTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLL 120

Query: 121 GGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYN 180
           GGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYN
Sbjct: 121 GGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYN 180

Query: 181 YGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRR 240
           YGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRR
Sbjct: 181 YGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRR 240

Query: 241 RRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASF 300
           RRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASF
Sbjct: 241 RRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASF 300

Query: 301 LQVHDFFQQDLKEGFHVSMLNRRTTPV 327
           LQVHDFFQQDLKEGFHVSMLNRRTTPV
Sbjct: 301 LQVHDFFQQDLKEGFHVSMLNRRTTPV 327


>gi|24586686 voltage-dependent calcium channel gamma-8 subunit [Homo
           sapiens]
          Length = 425

 Score =  379 bits (973), Expect = e-105
 Identities = 194/307 (63%), Positives = 233/307 (75%), Gaps = 21/307 (6%)

Query: 4   CDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTM--DDGPPPR------ 55
           C++G+Q+LLTT GAFAAF LM IAI TDYWLY+ A ICN TNLT   DDG P R      
Sbjct: 15  CEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGGDDGTPHRGGGGAS 74

Query: 56  --RARGDLTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPIL 113
             +  G LTHSGLWR+CC+EG+ +G C +INHFPED DYDHDS+EYLLR+VRASS+FPIL
Sbjct: 75  EKKDPGGLTHSGLWRICCLEGLKRGVCVKINHFPEDTDYDHDSAEYLLRVVRASSIFPIL 134

Query: 114 STILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDE 173
           S ILLLLGG+C+ A R+Y  K NI+L AGILFVAAGLSNIIG+IVYIS+N G+P  KRDE
Sbjct: 135 SAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRDE 194

Query: 174 DKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKA--------- 224
           +KKNHY+YGWSFYFG LSFI+AE +GVLAVNIYIE+++E   +++ + LKA         
Sbjct: 195 EKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQSRSDLLKAGGGAGGSGG 254

Query: 225 SSSSPYARMPSYRYR-RRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREP 283
           S  S   R+PSYR+R RRRSRSSSRS+E SPSRD SP G    G     ++SMYTLSR+P
Sbjct: 255 SGPSAILRLPSYRFRYRRRSRSSSRSSEPSPSRDASPGGPGGPG-FASTDISMYTLSRDP 313

Query: 284 LKVTTAA 290
            K + AA
Sbjct: 314 SKGSVAA 320


>gi|5174405 voltage-dependent calcium channel gamma-2 subunit [Homo
           sapiens]
          Length = 323

 Score =  376 bits (966), Expect = e-104
 Identities = 194/327 (59%), Positives = 251/327 (76%), Gaps = 12/327 (3%)

Query: 5   DRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHS 64
           DRG+QMLLTT GAFAAFSLM IA+GTDYWLYS   +C   +++ ++    ++    +THS
Sbjct: 5   DRGVQMLLTTVGAFAAFSLMTIAVGTDYWLYSRG-VCKTKSVSENE--TSKKNEEVMTHS 61

Query: 65  GLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLC 124
           GLWR CC+EG +KG C +I+HFPED DY+ D++EY LR VRASS+FPILS ILL +GGLC
Sbjct: 62  GLWRTCCLEGNFKGLCKQIDHFPEDADYEADTAEYFLRAVRASSIFPILSVILLFMGGLC 121

Query: 125 IGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWS 184
           I A   Y  ++NI+LSAGI FV+AGLSNIIGIIVYIS+N GDPS  + + KKN Y+YGWS
Sbjct: 122 IAASEFYKTRHNIILSAGIFFVSAGLSNIIGIIVYISANAGDPS--KSDSKKNSYSYGWS 179

Query: 185 FYFGALSFIVAETVGVLAVNIYIEKNKELRFKTK-REFLKASSSSPYARMPSYRYR-RRR 242
           FYFGALSFI+AE VGVLAV+++I+++K+LR   +  ++L+AS+     R+PSYRYR +RR
Sbjct: 180 FYFGALSFIIAEMVGVLAVHMFIDRHKQLRATARATDYLQASA---ITRIPSYRYRYQRR 236

Query: 243 SRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTT--AASYSPDQEASF 300
           SRSSSRSTE S SRD SP+G+K    +P  E+SMYTLSR+PLK  T   A+Y+ D++ SF
Sbjct: 237 SRSSSRSTEPSHSRDASPVGIKGFNTLPSTEISMYTLSRDPLKAATTPTATYNSDRDNSF 296

Query: 301 LQVHDFFQQDLKEGFHVSMLNRRTTPV 327
           LQVH+  Q++ K+  H +  NRRTTPV
Sbjct: 297 LQVHNCIQKENKDSLHSNTANRRTTPV 323


>gi|5729756 voltage-dependent calcium channel gamma-3 subunit [Homo
           sapiens]
          Length = 315

 Score =  358 bits (920), Expect = 3e-99
 Identities = 187/327 (57%), Positives = 238/327 (72%), Gaps = 12/327 (3%)

Query: 1   MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
           M  CDRG+QML+TT GAFAAFSLM IA+GTDYWLYS   +C   + +  D    R+    
Sbjct: 1   MRMCDRGIQMLITTVGAFAAFSLMTIAVGTDYWLYSRG-VCRTKSTS--DNETSRKNEEV 57

Query: 61  LTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLL 120
           +THSGLWR CC+EG ++G C +I+HFPED DY+ D++EYLLR VRASSVFPILS  LL  
Sbjct: 58  MTHSGLWRTCCLEGAFRGVCKKIDHFPEDADYEQDTAEYLLRAVRASSVFPILSVTLLFF 117

Query: 121 GGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYN 180
           GGLC+ A   +  ++N++LSAGI FV+AGLSNIIGIIVYIS+N GDP  +   D K  Y+
Sbjct: 118 GGLCVAASEFHRSRHNVILSAGIFFVSAGLSNIIGIIVYISANAGDPGQR---DSKKSYS 174

Query: 181 YGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPYARMPSYRYRR 240
           YGWSFYFGA SFI+AE VGV+AV+IYIEK+++LR K+  EFLK S+   +AR+P YRYR 
Sbjct: 175 YGWSFYFGAFSFIIAEIVGVVAVHIYIEKHQQLRAKSHSEFLKKST---FARLPPYRYRF 231

Query: 241 RRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASF 300
           RR RSSSRSTE   SRD+SP+  K    IP  ++SM+TLSR+P K+T     + D++ +F
Sbjct: 232 RR-RSSSRSTEPR-SRDLSPIS-KGFHTIPSTDISMFTLSRDPSKITMGTLLNSDRDHAF 288

Query: 301 LQVHDFFQQDLKEGFHVSMLNRRTTPV 327
           LQ H+   ++ KE  H +  NRRTTPV
Sbjct: 289 LQFHNSTPKEFKESLHNNPANRRTTPV 315


>gi|22027551 voltage-dependent calcium channel gamma-5 subunit
           isoform a [Homo sapiens]
          Length = 275

 Score =  125 bits (315), Expect = 4e-29
 Identities = 65/211 (30%), Positives = 117/211 (55%), Gaps = 10/211 (4%)

Query: 1   MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
           M  C R    LL++  A     L+ IA+ TDYWLY    +    N + +           
Sbjct: 1   MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMS------- 53

Query: 61  LTHSGLWRVCCIEGIYKGHCFRINH-FPEDNDYDHDSSEYLLRIVRASSVFPILSTILLL 119
             HSGLWRVC + G  +G CF I +  P +     +S+  +L+++R+++ FP++S   + 
Sbjct: 54  -LHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMF 112

Query: 120 LGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDK-RDEDKKNH 178
           +G +    G I   +  +   +GI F+ +GLS ++G+++YISS   +  ++ +D +   +
Sbjct: 113 IGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFN 172

Query: 179 YNYGWSFYFGALSFIVAETVGVLAVNIYIEK 209
           Y YGWSF F A+SF++ E+ GV++V +++++
Sbjct: 173 YKYGWSFAFAAISFLLTESAGVMSVYLFMKR 203


>gi|7656950 voltage-dependent calcium channel gamma-5 subunit
           isoform b [Homo sapiens]
          Length = 296

 Score =  116 bits (290), Expect = 3e-26
 Identities = 62/198 (31%), Positives = 106/198 (53%), Gaps = 10/198 (5%)

Query: 1   MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
           M  C R    LL++  A     L+ IA+ TDYWLY    +    N + +           
Sbjct: 1   MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMS------- 53

Query: 61  LTHSGLWRVCCIEGIYKGHCFRINH-FPEDNDYDHDSSEYLLRIVRASSVFPILSTILLL 119
             HSGLWRVC + G  +G CF I +  P +     +S+  +L+++R+++ FP++S   + 
Sbjct: 54  -LHSGLWRVCFLAGEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMF 112

Query: 120 LGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDK-RDEDKKNH 178
           +G +    G I   +  +   +GI F+ +GLS ++G+++YISS   +  ++ +D +   +
Sbjct: 113 IGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFN 172

Query: 179 YNYGWSFYFGALSFIVAE 196
           Y YGWSF F A+SF++ E
Sbjct: 173 YKYGWSFAFAAISFLLTE 190


>gi|21361975 voltage-dependent calcium channel gamma-7 subunit [Homo
           sapiens]
          Length = 275

 Score =  115 bits (289), Expect = 4e-26
 Identities = 67/214 (31%), Positives = 111/214 (51%), Gaps = 10/214 (4%)

Query: 1   MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGD 60
           M  C      LL++        L+ IA+ TDYWLY       GT L  +     + A   
Sbjct: 1   MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYME----EGTVLPQNQTTEVKMA--- 53

Query: 61  LTHSGLWRVCCIEGIYKGHCFRINHFPEDN-DYDHDSSEYLLRIVRASSVFPILSTILLL 119
             H+GLWRVC   G  KG C    +F E   +   +++E +L+ VR ++ FP++S  L+ 
Sbjct: 54  -LHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVF 112

Query: 120 LGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKN-H 178
              +    G I  ++  +   +GI F+ +GLS ++G+++YISS   +  ++    ++  H
Sbjct: 113 TAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFH 172

Query: 179 YNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKE 212
           Y YGWSF F A SF++ E  GV++V ++ ++  E
Sbjct: 173 YRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAE 206


>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 61/230 (26%), Positives = 98/230 (42%), Gaps = 32/230 (13%)

Query: 7   GLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDL----- 61
           GL       GA + F L+A AIGTD+W          T      GP  +   G +     
Sbjct: 7   GLAGAAALTGALS-FVLLAAAIGTDFWYIIDTERLERT------GPGAQDLLGSINRSQP 59

Query: 62  ----THSGLWRVCCIEGIYKGHCFRI-NHFPEDNDYDHDSSEYLLRIVRASSVFPILSTI 116
               +HSGLWR C ++      C  + N F  +N    +SS  LL +     +   LS I
Sbjct: 60  EPLSSHSGLWRTCRVQ----SPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLI 115

Query: 117 LLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRD--ED 174
           L++ GG+  G      +   ++L  GILF+   +  + GI VYI+ +     +     E+
Sbjct: 116 LMVFGGM-TGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEE 174

Query: 175 K----KNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKRE 220
           K    +   ++GWS   G +SFI     G      ++   +EL  + +++
Sbjct: 175 KALLDQVDISFGWSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220


>gi|226437592 transmembrane protein 114 [Homo sapiens]
          Length = 223

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 61/230 (26%), Positives = 98/230 (42%), Gaps = 32/230 (13%)

Query: 7   GLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDL----- 61
           GL       GA + F L+A AIGTD+W          T      GP  +   G +     
Sbjct: 7   GLAGAAALTGALS-FVLLAAAIGTDFWYIIDTERLERT------GPGAQDLLGSINRSQP 59

Query: 62  ----THSGLWRVCCIEGIYKGHCFRI-NHFPEDNDYDHDSSEYLLRIVRASSVFPILSTI 116
               +HSGLWR C ++      C  + N F  +N    +SS  LL +     +   LS I
Sbjct: 60  EPLSSHSGLWRTCRVQ----SPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLI 115

Query: 117 LLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRD--ED 174
           L++ GG+  G      +   ++L  GILF+   +  + GI VYI+ +     +     E+
Sbjct: 116 LMVFGGM-TGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEE 174

Query: 175 K----KNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKRE 220
           K    +   ++GWS   G +SFI     G      ++   +EL  + +++
Sbjct: 175 KALLDQVDISFGWSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 220


>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
           sapiens]
          Length = 217

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 61/224 (27%), Positives = 97/224 (43%), Gaps = 20/224 (8%)

Query: 7   GLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDD--GPPPRRARGDLT-H 63
           GL       GA + F L+A AIGT++W          T     D  G   R     L+ H
Sbjct: 1   GLAGAAALTGALS-FVLLAAAIGTEFWYIIDTERLERTGPGAQDLLGSINRSQPEPLSSH 59

Query: 64  SGLWRVCCIEGIYKGHCFRI-NHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGG 122
           SGLWR C ++      C  + N F  +N    +SS  LL +     +   LS IL++ GG
Sbjct: 60  SGLWRTCRVQ----SPCTPLMNPFRLENVTVSESSRQLLTMHGTFVILLPLSLILMVFGG 115

Query: 123 LCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRD--EDK----K 176
           +  G      +   ++L  GILF+   +  + GI VYI+ +     +     E+K    +
Sbjct: 116 M-TGFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALCLLEEKALLDQ 174

Query: 177 NHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKRE 220
              ++GWS   G +SFI     G      ++   +EL  + +++
Sbjct: 175 VDISFGWSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 214


>gi|123317881 germ cell associated 1 isoform 4 [Homo sapiens]
          Length = 362

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 8/121 (6%)

Query: 110 FPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSD 169
           F +L T LLL G    G          +   A +  V +GL  ++  ++Y        + 
Sbjct: 181 FLLLLTDLLLTGNPACGL--------KLSAFAAVSSVLSGLLGMVAHMMYSQVFQATVNL 232

Query: 170 KRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSP 229
             ++ + + +NYGW+FY   LSF       V   N Y     E + K  + F +  +  P
Sbjct: 233 GPEDWRPHVWNYGWAFYMAWLSFTCCMASAVTTFNTYTRMVLEFKCKHSKSFKENPNCLP 292

Query: 230 Y 230
           +
Sbjct: 293 H 293


>gi|123317861 germ cell associated 1 isoform 2 [Homo sapiens]
          Length = 326

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 29/121 (23%), Positives = 49/121 (40%), Gaps = 8/121 (6%)

Query: 110 FPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSD 169
           F +L T LLL G    G          +   A +  V +GL  ++  ++Y        + 
Sbjct: 145 FLLLLTDLLLTGNPACGL--------KLSAFAAVSSVLSGLLGMVAHMMYSQVFQATVNL 196

Query: 170 KRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSP 229
             ++ + + +NYGW+FY   LSF       V   N Y     E + K  + F +  +  P
Sbjct: 197 GPEDWRPHVWNYGWAFYMAWLSFTCCMASAVTTFNTYTRMVLEFKCKHSKSFKENPNCLP 256

Query: 230 Y 230
           +
Sbjct: 257 H 257


>gi|5921465 claudin 10 isoform b [Homo sapiens]
          Length = 228

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 47/214 (21%), Positives = 81/214 (37%), Gaps = 20/214 (9%)

Query: 17  AFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIY 76
           + + + L++  + TDYW  S+    +GT +T                + LW+ C  +   
Sbjct: 14  SISGWVLVSSTLPTDYWKVSTI---DGTVITTAT-----------YWANLWKACVTDSTG 59

Query: 77  KGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNN 136
             +C     FP     D         ++ A S+     +I  L G  C   G     K  
Sbjct: 60  VSNC---KDFPSMLALDGYIQACRGLMIAAVSL-GFFGSIFALFGMKCTKVGGSDKAKAK 115

Query: 137 IVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAE 196
           I   AGI+F+ +GL ++ G  +Y +  T +  D    ++K  Y  G + + G     +  
Sbjct: 116 IACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQK--YELGAALFIGWAGASLCI 173

Query: 197 TVGVLAVNIYIEKNKELRFKTKREFLKASSSSPY 230
             GV+      + NK  R+         SS + Y
Sbjct: 174 IGGVIFCFSISDNNKTPRYTYNGATSVMSSRTKY 207


>gi|4502539 voltage-dependent calcium channel gamma-1 subunit [Homo
           sapiens]
          Length = 222

 Score = 37.7 bits (86), Expect = 0.014
 Identities = 48/205 (23%), Positives = 79/205 (38%), Gaps = 38/205 (18%)

Query: 8   LQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLW 67
           L++ +T     A   L   A+ TD+W   S H+    N T +             H GLW
Sbjct: 7   LKVRVTLFCILAGIVLAMTAVVTDHWAVLSPHM-EHHNTTCE-----------AAHFGLW 54

Query: 68  RVC-----------CIEGIYKG--HCFRINHF-PEDNDYDHDSSEYLLRIVRASSVFPIL 113
           R+C           C      G  +C    HF P ++    + +      + A+++  I 
Sbjct: 55  RICTKRIPMDDSKTCGPITLPGEKNCSYFRHFNPGESSEIFEFTTQKEYSISAAAI-AIF 113

Query: 114 STILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDE 173
           S   ++LG LC+       +K + +L    +F A       G+ + +S      S KR  
Sbjct: 114 SLGFIILGSLCVLLS--LGKKRDYLLRPASMFYA-----FAGLCILVSVEVMRQSVKRMI 166

Query: 174 DKKN----HYNYGWSFYFGALSFIV 194
           D ++     Y Y WSF     +FI+
Sbjct: 167 DSEDTVWIEYYYSWSFACACAAFIL 191


>gi|33598916 claudin 10 isoform a [Homo sapiens]
          Length = 226

 Score = 36.6 bits (83), Expect = 0.031
 Identities = 41/168 (24%), Positives = 63/168 (37%), Gaps = 6/168 (3%)

Query: 63  HSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGG 122
           + GLW  C    +   HC    HF       +  +   L I   S  F    +I  L G 
Sbjct: 44  YQGLWMNCAGNALGSFHCRP--HFTIFKVAGYIQACRGLMIAAVSLGF--FGSIFALFGM 99

Query: 123 LCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYG 182
            C   G     K  I   AGI+F+ +GL ++ G  +Y +  T +  D    ++K  Y  G
Sbjct: 100 KCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQK--YELG 157

Query: 183 WSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPY 230
            + + G     +    GV+      + NK  R+         SS + Y
Sbjct: 158 AALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMSSRTKY 205


>gi|239916002 lens intrinsic membrane protein 2, 19kDa isoform 2
           [Homo sapiens]
          Length = 173

 Score = 35.4 bits (80), Expect = 0.070
 Identities = 41/193 (21%), Positives = 72/193 (37%), Gaps = 46/193 (23%)

Query: 17  AFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLWRVCCIEGIY 76
           A+    L+ +A+ TD+W+                     R  G   H GLWR C     Y
Sbjct: 12  AWVGTILLVVAMATDHWMQY-------------------RLSGSFAHQGLWRYCLGNKCY 52

Query: 77  KGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLG---GLCIGAGRIYSR 133
                             DS  Y      A+  F ILS +  + G   G+   A +    
Sbjct: 53  ---------------LQTDSIAYW----NATRAFMILSALCAISGIIMGIMAFAHQPTFS 93

Query: 134 KNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFI 193
           + +   SAGI+F ++ L  ++ + +Y +  T     +R  D    + + WS+  G ++ +
Sbjct: 94  RISRPFSAGIMFFSSTLFVVLALAIY-TGVTVSFLGRRFGD----WRFSWSYILGWVAVL 148

Query: 194 VAETVGVLAVNIY 206
           +    G+  +  Y
Sbjct: 149 MTFFAGIFYMCAY 161


>gi|50345279 claudin 18 isoform 2 [Homo sapiens]
          Length = 261

 Score = 35.4 bits (80), Expect = 0.070
 Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 19/105 (18%)

Query: 63  HSGLWRVCCIEGIYKGHC---FRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLL 119
           + GLWR C  E      C   F +   P            +L+ VRA  +  I+   + L
Sbjct: 46  YQGLWRSCVRESSGFTECRGYFTLLGLPA-----------MLQAVRALMIVGIVLGAIGL 94

Query: 120 LGGL----CIGAGRIY-SRKNNIVLSAGILFVAAGLSNIIGIIVY 159
           L  +    CI  G +  S K N+ L++GI+F+ +GL  I G+ V+
Sbjct: 95  LVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVF 139


>gi|7656981 claudin 15 [Homo sapiens]
          Length = 228

 Score = 35.4 bits (80), Expect = 0.070
 Identities = 44/189 (23%), Positives = 71/189 (37%), Gaps = 32/189 (16%)

Query: 8   LQMLLTTAGAFAA---FSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHS 64
           + M + T G F A     ++ + +   YW  S+ H   G  +T +               
Sbjct: 1   MSMAVETFGFFMATVGLLMLGVTLPNSYWRVSTVH---GNVITTNT-----------IFE 46

Query: 65  GLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGL- 123
            LW  C  + +   +C+        + Y        ++  RA  +  IL   L LL G+ 
Sbjct: 47  NLWFSCATDSLGVYNCWEFPSMLALSGY--------IQACRALMITAILLGFLGLLLGIA 98

Query: 124 ---CIGAGRI-YSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHY 179
              C   G +  SRK  +  +AG L + AG+  ++ I  Y  + T D  D      K  Y
Sbjct: 99  GLRCTNIGGLELSRKAKLAATAGALHILAGICGMVAISWYAFNITRDFFDPLYPGTK--Y 156

Query: 180 NYGWSFYFG 188
             G + Y G
Sbjct: 157 ELGPALYLG 165


>gi|88758580 cyclin L2 isoform A [Homo sapiens]
          Length = 520

 Score = 35.0 bits (79), Expect = 0.091
 Identities = 22/59 (37%), Positives = 26/59 (44%)

Query: 223 KASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSR 281
           KA + SP   +P  R  R RSRS  +S   SPSR  SP   K       G     + SR
Sbjct: 364 KAKADSPVNGLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSGSTSGGSKSQSRSR 422


>gi|7705961 claudin 18 isoform 1 [Homo sapiens]
          Length = 261

 Score = 35.0 bits (79), Expect = 0.091
 Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 19/105 (18%)

Query: 63  HSGLWRVCCIEGIYKGHC---FRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLL 119
           + GLWR C  +      C   F I   P            +L+ VRA  +  I+   + L
Sbjct: 46  YEGLWRSCVRQSSGFTECRPYFTILGLPA-----------MLQAVRALMIVGIVLGAIGL 94

Query: 120 LGGL----CIGAGRIY-SRKNNIVLSAGILFVAAGLSNIIGIIVY 159
           L  +    CI  G +  S K N+ L++GI+F+ +GL  I G+ V+
Sbjct: 95  LVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVF 139


>gi|231569235 claudin 10 isoform a_i1 [Homo sapiens]
          Length = 207

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 29/116 (25%), Positives = 47/116 (40%), Gaps = 2/116 (1%)

Query: 115 TILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDED 174
           +I  L G  C   G     K  I   AGI+F+ +GL ++ G  +Y +  T +  D    +
Sbjct: 73  SIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVE 132

Query: 175 KKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSSPY 230
           +K  Y  G + + G     +    GV+      + NK  R+         SS + Y
Sbjct: 133 QK--YELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMSSRTKY 186


>gi|22748835 transmembrane protein 178 [Homo sapiens]
          Length = 297

 Score = 33.5 bits (75), Expect = 0.26
 Identities = 48/188 (25%), Positives = 79/188 (42%), Gaps = 32/188 (17%)

Query: 62  THSGLWRVCCIEG--------IYKG---HC----------FRINHFPEDNDYDHDSSE-Y 99
           T+SGLWR C   G        I KG    C           R+ + P +        E +
Sbjct: 110 TYSGLWRKCYFLGIDRDIDTLILKGIAQRCTAIKYHFSQPIRLRNIPFNLTKTIQQDEWH 169

Query: 100 LLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLS-AGILFVAAGLSNIIGIIV 158
           LL + R ++ F  ++  +LL G  CI A   +  + ++    AG+LF+  G+   I +  
Sbjct: 170 LLHLRRITAGFLGMAVAVLLCG--CIVATVSFFWEESLTQHVAGLLFLMTGIFCTISLCT 227

Query: 159 YISSNTGD----PSDKRDEDKKNHYNYGWSFY--FGALSFIVAETVGVLAVNIYIEKNKE 212
           Y +S + D    P           + Y WS +  + +L FIVA   G+     +I + K 
Sbjct: 228 YAASISYDLNRLPKLIYSLPADVEHGYSWSIFCAWCSLGFIVA-AGGLCIAYPFISRTKI 286

Query: 213 LRFKTKRE 220
            + K+ R+
Sbjct: 287 AQLKSGRD 294


>gi|157951718 GSG1-like isoform 1 [Homo sapiens]
          Length = 331

 Score = 33.1 bits (74), Expect = 0.35
 Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 5/108 (4%)

Query: 116 ILLLLGGLCIGAGRIYSRKN-----NIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDK 170
           ILLL+ G  +    ++   N      +   A +  V +GL  ++  ++Y        S  
Sbjct: 146 ILLLVVGFSLMCLELFHSSNVIDGLKLNAFAAVFTVLSGLLGMVAHMMYTQVFQVTVSLG 205

Query: 171 RDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTK 218
            ++ + + ++YGWSF     SF       V  +N Y +   E R K K
Sbjct: 206 PEDWRPHSWDYGWSFCLAWGSFTCCMAASVTTLNSYTKTVIEFRHKRK 253


>gi|22027554 voltage-dependent calcium channel gamma-6 subunit
           isoform a [Homo sapiens]
          Length = 260

 Score = 32.3 bits (72), Expect = 0.59
 Identities = 41/202 (20%), Positives = 76/202 (37%), Gaps = 39/202 (19%)

Query: 8   LQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLW 67
           L +LL   GA    +L  +++GT++W+  + +  NG+            A  +  H GLW
Sbjct: 41  LALLLAAVGA----TLAVLSVGTEFWVELNTYKANGS------------AVCEAAHLGLW 84

Query: 68  RVCC-----------------IEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVF 110
           + C                   E   + +C     F    +           +  A++V 
Sbjct: 85  KACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVI 144

Query: 111 PILSTILLLLGGLCIGAGRIYSRKNNIVLSAG-ILFVAAGLSNIIGIIVY---ISSNTGD 166
            +L   ++ LG LCI    + S+    +L  G + F  +GL  ++ + V+   + +    
Sbjct: 145 AVLGLAVMALGCLCI--IMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVRALLQR 202

Query: 167 PSDKRDEDKKNHYNYGWSFYFG 188
            S +     +  Y Y WS   G
Sbjct: 203 VSPEPPPAPRLTYEYSWSLGCG 224


>gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]
          Length = 122

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 11/114 (9%)

Query: 113 LSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRD 172
           LS IL++ GG+  G      +   ++L  GILF+   +  + GI VYI+ +     +   
Sbjct: 11  LSLILMVFGGMT-GFLSFLLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAAFREALC 69

Query: 173 --EDK----KNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKRE 220
             E+K    +   ++GWS   G +SFI     G      ++   +EL  + +++
Sbjct: 70  LLEEKALLDQVDISFGWSLALGWISFIAELLTGA----AFLAAARELSLRRRQD 119


>gi|34304336 ring finger protein 8 isoform 2 [Homo sapiens]
          Length = 448

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 27/86 (31%), Positives = 33/86 (38%), Gaps = 8/86 (9%)

Query: 207 IEKNKELRFKTKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDVSPMGLKIT 266
           IEKNKELR  TKR+F     + P A  PS        +S          + V   G    
Sbjct: 144 IEKNKELR--TKRKFSLDELAGPGAEGPS------NLKSKINKVSCESGQPVKSQGKGEV 195

Query: 267 GAIPMGELSMYTLSREPLKVTTAASY 292
            + P   L     + EP K T A  Y
Sbjct: 196 ASTPSDNLDPKLTALEPSKTTGAPIY 221


>gi|4504867 ring finger protein 8 isoform 1 [Homo sapiens]
          Length = 485

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 27/86 (31%), Positives = 33/86 (38%), Gaps = 8/86 (9%)

Query: 207 IEKNKELRFKTKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDVSPMGLKIT 266
           IEKNKELR  TKR+F     + P A  PS        +S          + V   G    
Sbjct: 144 IEKNKELR--TKRKFSLDELAGPGAEGPS------NLKSKINKVSCESGQPVKSQGKGEV 195

Query: 267 GAIPMGELSMYTLSREPLKVTTAASY 292
            + P   L     + EP K T A  Y
Sbjct: 196 ASTPSDNLDPKLTALEPSKTTGAPIY 221


>gi|21389571 GSG1-like isoform 2 [Homo sapiens]
          Length = 176

 Score = 32.0 bits (71), Expect = 0.77
 Identities = 20/78 (25%), Positives = 34/78 (43%)

Query: 141 AGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGV 200
           A +  V +GL  ++  ++Y        S   ++ + + ++YGWSF     SF       V
Sbjct: 21  AAVFTVLSGLLGMVAHMMYTQVFQVTVSLGPEDWRPHSWDYGWSFCLAWGSFTCCMAASV 80

Query: 201 LAVNIYIEKNKELRFKTK 218
             +N Y +   E R K K
Sbjct: 81  TTLNSYTKTVIEFRHKRK 98


>gi|4502877 claudin 4 [Homo sapiens]
          Length = 209

 Score = 31.6 bits (70), Expect = 1.0
 Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 10/95 (10%)

Query: 65  GLWRVCCIEGIYKGHCFRINHF---PEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLG 121
           GLW  C ++   +  C   +     P+D        +    +V  S +   L  +L ++G
Sbjct: 49  GLWMNCVVQSTGQMQCKVYDSLLALPQD-------LQAARALVIISIIVAALGVLLSVVG 101

Query: 122 GLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGI 156
           G C       S K   ++ AG++F+ AGL  I+ +
Sbjct: 102 GKCTNCLEDESAKAKTMIVAGVVFLLAGLMVIVPV 136


>gi|22027560 voltage-dependent calcium channel gamma-6 subunit
          isoform c [Homo sapiens]
          Length = 189

 Score = 31.2 bits (69), Expect = 1.3
 Identities = 17/63 (26%), Positives = 30/63 (47%), Gaps = 16/63 (25%)

Query: 8  LQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPPPRRARGDLTHSGLW 67
          L +LL   GA    +L  +++GT++W+  + +  NG+            A  +  H GLW
Sbjct: 41 LALLLAAVGA----TLAVLSVGTEFWVELNTYKANGS------------AVCEAAHLGLW 84

Query: 68 RVC 70
          + C
Sbjct: 85 KAC 87


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,135,709
Number of Sequences: 37866
Number of extensions: 539206
Number of successful extensions: 1994
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 1860
Number of HSP's gapped (non-prelim): 133
length of query: 327
length of database: 18,247,518
effective HSP length: 103
effective length of query: 224
effective length of database: 14,347,320
effective search space: 3213799680
effective search space used: 3213799680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.