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Search of human proteins with 74325776
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens]
(213 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens] 429 e-121
gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens] 372 e-103
gi|24415404 MDN1, midasin homolog [Homo sapiens] 62 5e-10
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 55 3e-08
gi|210032580 SET domain containing 1B [Homo sapiens] 52 5e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 51 6e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 51 8e-07
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 49 3e-06
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 49 3e-06
gi|46409304 glutamate-rich 1 [Homo sapiens] 49 3e-06
gi|156104891 general transcription factor IIF, polypeptide 1, 74... 49 4e-06
gi|55956788 nucleolin [Homo sapiens] 48 5e-06
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 48 5e-06
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 48 5e-06
gi|16445033 ACRC protein [Homo sapiens] 47 9e-06
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 47 9e-06
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 47 1e-05
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 47 2e-05
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 47 2e-05
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 47 2e-05
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 47 2e-05
gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapi... 47 2e-05
gi|21735569 claspin [Homo sapiens] 46 2e-05
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 46 2e-05
gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 fami... 46 2e-05
gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 46 2e-05
gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32 fam... 46 2e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 46 3e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 46 3e-05
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 45 4e-05
>gi|74325776 MACRO domain containing 2 isoform 2 [Homo sapiens]
Length = 213
Score = 429 bits (1104), Expect = e-121
Identities = 213/213 (100%), Positives = 213/213 (100%)
Query: 1 MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA 60
MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA
Sbjct: 1 MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA 60
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 120
VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL
Sbjct: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 120
Query: 121 SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNS 180
SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNS
Sbjct: 121 SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNS 180
Query: 181 QVDKVNDPTESQQEDQLIAGAQDEAKEQRNGTK 213
QVDKVNDPTESQQEDQLIAGAQDEAKEQRNGTK
Sbjct: 181 QVDKVNDPTESQQEDQLIAGAQDEAKEQRNGTK 213
>gi|117968621 MACRO domain containing 2 isoform 1 [Homo sapiens]
Length = 425
Score = 372 bits (955), Expect = e-103
Identities = 190/213 (89%), Positives = 190/213 (89%), Gaps = 23/213 (10%)
Query: 1 MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA 60
MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA
Sbjct: 236 MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA 295
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 120
VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL
Sbjct: 296 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 355
Query: 121 SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNS 180
SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPD
Sbjct: 356 SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPD----- 410
Query: 181 QVDKVNDPTESQQEDQLIAGAQDEAKEQRNGTK 213
AGAQDEAKEQRNGTK
Sbjct: 411 ------------------AGAQDEAKEQRNGTK 425
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 61.6 bits (148), Expect = 5e-10
Identities = 53/220 (24%), Positives = 92/220 (41%), Gaps = 27/220 (12%)
Query: 8 DDNNEEEEDVEMKEDS----------DENGPEEKQSVEEM------EEQSQDADGVNTVT 51
D EE+E+ + K DS D NG E + E + EE ++ D T
Sbjct: 4739 DGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEET 4798
Query: 52 VPGPASEEAVEDCKDEDFAKDENITKGGEVTDHSVRD--QDHPDGQENDSTKNEIKIETE 109
PG E++ E AKD+N+ G D S +D ++ + + +D + E KI +
Sbjct: 4799 GPGMDEEDS------ELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQ 4852
Query: 110 SQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLE 169
+ E+ + V +PE + L +D +K GEDT G+ E +++
Sbjct: 4853 IDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTDNEEGEEENPLEIK 4912
Query: 170 NTP---GPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAK 206
P G + E + + + ++S QE + D+A+
Sbjct: 4913 EKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAE 4952
Score = 39.3 bits (90), Expect = 0.003
Identities = 43/191 (22%), Positives = 76/191 (39%), Gaps = 19/191 (9%)
Query: 15 EDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDEN 74
ED + +E +EN E K+ EE ++++ T + +E E ++D A
Sbjct: 4896 EDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKA---- 4951
Query: 75 ITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPE 134
+G E D DQD Q + E + E + + E + D Q E
Sbjct: 4952 --EGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEE 5009
Query: 135 VIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVND--PTESQ 192
E++E+ + E+ E R S G + +EN N+Q ++ P + Q
Sbjct: 5010 -----EEREDSDTEEQVPEALERKEHASCGQTGVENM------QNTQAMELAGAAPEKEQ 5058
Query: 193 QEDQLIAGAQD 203
+++ +GA D
Sbjct: 5059 GKEEHGSGAAD 5069
Score = 37.7 bits (86), Expect = 0.007
Identities = 49/209 (23%), Positives = 79/209 (37%), Gaps = 41/209 (19%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
DD N + ED ED+D EE+ +E E+ P A EA E + E
Sbjct: 4883 DDLNLDSEDKNGGEDTDNEEGEEENPLEIKEK-------------PEEAGHEAEERGETE 4929
Query: 68 DFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDA 127
D+N ++ + + + D +G+E T + + + EE S Q+ +
Sbjct: 4930 T---DQNESQSPQEPEEGPSEDDKAEGEEEMDT----GADDQDGDAAQHPEEHSEEQQQS 4982
Query: 128 VIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPG------KSEGSSDLENTPGPDVEMNSQ 181
V ++++KE ++ GE+ P G + SD E +E
Sbjct: 4983 V------------EEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEEQVPEALERKEH 5030
Query: 182 VDKVNDPTESQQEDQL--IAGAQDEAKEQ 208
E+ Q Q +AGA E KEQ
Sbjct: 5031 ASCGQTGVENMQNTQAMELAGAAPE-KEQ 5058
Score = 37.7 bits (86), Expect = 0.007
Identities = 35/144 (24%), Positives = 63/144 (43%), Gaps = 9/144 (6%)
Query: 9 DNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDED 68
D NE + E +E E+ E + EEM+ + D DG + P SEE + +++D
Sbjct: 4931 DQNESQSPQEPEEGPSEDDKAEGE--EEMDTGADDQDG-DAAQHPEEHSEEQQQSVEEKD 4987
Query: 69 FAKDENITKGGE--VTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQED 126
DE +GGE D + Q+ + +++D T+ ++ E + + N ++
Sbjct: 4988 KEADE---EGGENGPADQGFQPQEEEEREDSD-TEEQVPEALERKEHASCGQTGVENMQN 5043
Query: 127 AVIVEQPEVIPLTEDQEEKEGEKA 150
+E P E +E+ G A
Sbjct: 5044 TQAMELAGAAPEKEQGKEEHGSGA 5067
Score = 32.3 bits (72), Expect = 0.31
Identities = 43/192 (22%), Positives = 78/192 (40%), Gaps = 48/192 (25%)
Query: 19 MKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKG 78
MK+ SD+ G EE+ VE+ ++ Q+ D ++ D K ED A + +
Sbjct: 4686 MKDVSDQIGNEEQ--VEDTFQKGQEKD---------KEDPDSKSDIKGEDNAIEMSEDFD 4734
Query: 79 GEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPEVIPL 138
G++ D + +Q+ D +++DS E +L + D L
Sbjct: 4735 GKMHDGELEEQEEDD-EKSDS----------------EGGDLDKHMGD-----------L 4766
Query: 139 TEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLI 198
++ +K E+ G+D + E + E PG D E + V K +D L
Sbjct: 4767 NGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAK---------DDNLD 4817
Query: 199 AGAQDEAKEQRN 210
+G ++ K Q++
Sbjct: 4818 SGNSNKDKSQQD 4829
Score = 30.4 bits (67), Expect = 1.2
Identities = 32/143 (22%), Positives = 63/143 (44%), Gaps = 19/143 (13%)
Query: 54 GPASEEAVEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSS 113
GPA + + ED E+I +G + D D + Q++ + + E E + +
Sbjct: 5133 GPAQQPQAQV---EDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDT 5189
Query: 114 YMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPG 173
M+TEE QE+ + ++ P +E K G AP G E +++ T
Sbjct: 5190 LMDTEE----QEEFKAADVEQLKP----EEIKSGTTAP-------LGFDEMEVEIQ-TVK 5233
Query: 174 PDVEMNSQVDKVNDPTESQQEDQ 196
+ + + + DK + TE+++ ++
Sbjct: 5234 TEEDQDPRTDKAHKETENEKPER 5256
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 55.5 bits (132), Expect = 3e-08
Identities = 48/203 (23%), Positives = 93/203 (45%), Gaps = 27/203 (13%)
Query: 13 EEEDVEMKE----DSDENGPEEKQSVE---EMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
E+E VE+KE D+ E G E+K++V + EE+ Q D + G A +E ++
Sbjct: 94 EKEIVEVKEENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKG 153
Query: 66 DEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQE 125
+ED +D+N G E + + +D G++ + K + E + + +E +E
Sbjct: 154 EEDGKEDKN---GNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKE 210
Query: 126 DAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKV 185
+ ED +EK G+K G+D + E E+ G + E + + +
Sbjct: 211 N-------------EDGKEK-GDKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDL 256
Query: 186 NDPTESQQEDQLIAGAQDEAKEQ 208
+ E ++ED++ +D+ K++
Sbjct: 257 KEEEEGKEEDEI---KEDDGKKE 276
Score = 43.5 bits (101), Expect = 1e-04
Identities = 51/220 (23%), Positives = 90/220 (40%), Gaps = 36/220 (16%)
Query: 19 MKEDSDENGP---EEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENI 75
M+E+ D + E KQ E+ +++A PASE+ + + K+E+ ++
Sbjct: 52 MEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVKEENI--EDAT 109
Query: 76 TKGGEVTDHSVRD--QDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQP 133
KGGE + + + D +E++ +NE K E + + EE +ED E+
Sbjct: 110 EKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEE--DGKEDKNGNEKG 167
Query: 134 EVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLE---------------------NTP 172
E ED ++ E K GED GK +G + E
Sbjct: 168 EDAKEKEDGKKGEDGKGNGED-----GKEKGEDEKEEEDRKETGDGKENEDGKEKGDKKE 222
Query: 173 GPDVEMNSQVDKVNDPTESQQEDQLIAGAQ-DEAKEQRNG 211
G DV++ + D E + ++ AG + ++ KE+ G
Sbjct: 223 GKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEG 262
Score = 42.0 bits (97), Expect = 4e-04
Identities = 40/153 (26%), Positives = 69/153 (45%), Gaps = 21/153 (13%)
Query: 8 DDNNEEEEDVEMKEDSDE----NGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVED 63
+D NEE+ + KED DE +G E+K E+ E+ + DG G E+ E
Sbjct: 135 EDQNEEKGEAG-KEDKDEKGEEDGKEDKNGNEKGEDAKEKEDGKKGEDGKG-NGEDGKEK 192
Query: 64 CKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTK--NEIKIETESQSSYMETEELS 121
+DE +D T G +++ DG+E K ++K++ + + E+
Sbjct: 193 GEDEKEEEDRKETGDG---------KENEDGKEKGDKKEGKDVKVKEDEKEREDGKEDEG 243
Query: 122 SNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGED 154
N+E+A E L E++E KE ++ +D
Sbjct: 244 GNEEEA----GKEKEDLKEEEEGKEEDEIKEDD 272
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 51.6 bits (122), Expect = 5e-07
Identities = 47/189 (24%), Positives = 77/189 (40%), Gaps = 24/189 (12%)
Query: 7 VDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKD 66
+D EE+E + E+ + EE+ EE EE D D D +D
Sbjct: 1029 LDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDD----------------SDDRD 1072
Query: 67 EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQED 126
E DE+ +++ S +D+ D +E S T S S +E SS++
Sbjct: 1073 ESENDDEDTA----LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESS 1128
Query: 127 AVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLEN---TPG-PDVEMNSQV 182
E E + E++EE+E E+ E++ G + D E PG P V+
Sbjct: 1129 PSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGME 1188
Query: 183 DKVNDPTES 191
++V+ TE+
Sbjct: 1189 EEVDIETEA 1197
Score = 48.5 bits (114), Expect = 4e-06
Identities = 40/201 (19%), Positives = 85/201 (42%), Gaps = 20/201 (9%)
Query: 12 EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDF-- 69
+ +E + D+ SV+E +E+S+ + P E A D K
Sbjct: 965 KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTP---CELAKRDPKGVGVRR 1021
Query: 70 --AKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDA 127
A+ + GGE + ++ +E + + E + E + + +E ++ ED
Sbjct: 1022 RPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDT 1081
Query: 128 VIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVND 187
L+E E+ EG+ E + K+E +S E++ + E +S+ +
Sbjct: 1082 A---------LSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSE----SS 1128
Query: 188 PTESQQEDQLIAGAQDEAKEQ 208
P+ S+ E++++A ++E +E+
Sbjct: 1129 PSSSEDEEEVVAREEEEEEEE 1149
Score = 43.1 bits (100), Expect = 2e-04
Identities = 48/219 (21%), Positives = 86/219 (39%), Gaps = 35/219 (15%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
S ++ E EE+ E ++D D++ + +S + E+ T ASE+ D
Sbjct: 1047 STEEEEEAEEEEEEEDDDDDDSDDRDESENDDED-----------TALSEASEKDEGDSD 1095
Query: 66 DEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQE 125
+E+ +T E T S + + E +S+ +E + + EE +E
Sbjct: 1096 EEETV--SIVTSKAEATSSS----ESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEE 1149
Query: 126 DAVIVEQPEVIPLTED--QEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVD 183
+ ++ E+ ED Q+ +E APG G E D+E E S +D
Sbjct: 1150 EEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEE-EVDIETEAVAPEERPSMLD 1208
Query: 184 K------VNDPTESQ---------QEDQLIAGAQDEAKE 207
+ V +P +S+ QE ++ + AKE
Sbjct: 1209 EPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKE 1247
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 51.2 bits (121), Expect = 6e-07
Identities = 50/223 (22%), Positives = 98/223 (43%), Gaps = 23/223 (10%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEE------QSQDADGVNTVTVPGPASEE 59
+++ ++EEEE+ E +E+ +E EE++ EE EE + ++ + E
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941
Query: 60 AVEDCKDEDFAKDENI---------TKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETES 110
E+ ++ED ++E + T GGEV + + P + +++ E E
Sbjct: 942 LEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEP 1001
Query: 111 QSS-YMETEELSSNQE---DAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSS 166
+ +E EE + +E D PE +P ++ + E+EGE P+ + E S+
Sbjct: 1002 EPGLLLEVEEPGTEEERGADTAPTLAPEALP-SQGEVEREGESPAAGPPPQELVEEEPSA 1060
Query: 167 DLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQR 209
+ E DKV P E+ E+++ + EA +++
Sbjct: 1061 PPTLL---EEETEDGSDKVQPPPETPAEEEMETETEAEALQEK 1100
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 50.8 bits (120), Expect = 8e-07
Identities = 50/219 (22%), Positives = 95/219 (43%), Gaps = 23/219 (10%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQ-DADGVNTVTVPGPASEEAV 61
E V+ +E E E D PE + ++E EE++Q ++DGV EA
Sbjct: 1978 EALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGV-----------EAQ 2026
Query: 62 EDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELS 121
+ E+ + E T+ E D E ++ + E +++ ++ E+E++
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD 2086
Query: 122 SNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQ 181
+ + + QPE + + E E +KA G + P G+++ S E P+ E +Q
Sbjct: 2087 AQEAEGEA--QPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPES--EGIEAPEAEGEAQ 2142
Query: 182 -----VDKVNDPTESQQEDQLIAG--AQDEAKEQRNGTK 213
V+ + E+Q E + I A++EA+ + G +
Sbjct: 2143 PESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVE 2181
Score = 48.1 bits (113), Expect = 5e-06
Identities = 53/225 (23%), Positives = 86/225 (38%), Gaps = 29/225 (12%)
Query: 13 EEEDVEMKEDSDENGPE-EKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDC--KDEDF 69
E E VE E E+ PE E +E EE +Q+A+G S+EA E+ + ED
Sbjct: 1918 ETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDV 1977
Query: 70 AKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVI 129
E + E + + + + E + E + E + +S +E + S +E +
Sbjct: 1978 EALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEV 2037
Query: 130 -----------------VEQPEVIPLTEDQE----EKEGEKAP-GEDTPRMPGKSEGSSD 167
VE PE ++ E E EGE P ED + E +
Sbjct: 2038 EGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPE 2097
Query: 168 LENTPGPDVEMNSQ----VDKVNDPTESQQEDQLIAGAQDEAKEQ 208
E P+ E +Q ++ E+Q E + I + E + Q
Sbjct: 2098 SEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQ 2142
Score = 40.4 bits (93), Expect = 0.001
Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 8/168 (4%)
Query: 12 EEEEDVEMKEDSDENGPEEK--QSVEEMEEQSQDADGVNTVTVPGPASEEA--VEDCKDE 67
++ E +E E E PE + ++ E E +++GV G A E+ +E + E
Sbjct: 2111 QKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAE 2170
Query: 68 DFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDA 127
+ A+ E +G E + Q +G E + E + E E + E EE + + +
Sbjct: 2171 EEAQPE--LEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEA-PEAEEEAQPEPEG 2227
Query: 128 VIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPD 175
V + E E + E +GEK G+SE +S+ ++P P+
Sbjct: 2228 VETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASE-SSSPVPE 2274
Score = 38.9 bits (89), Expect = 0.003
Identities = 41/206 (19%), Positives = 81/206 (39%), Gaps = 7/206 (3%)
Query: 13 EEEDVEMKEDSDENGPEEKQSVEEMEEQSQ-DADGVNTVTVPGPASEEAVEDCKDEDFAK 71
E E E PE + +E E ++Q +++ V G A E+ + E +
Sbjct: 1839 EAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWE 1898
Query: 72 DENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVE 131
+ ++G E + Q P+ + ++ + E + E ES+ + + E ++ + +
Sbjct: 1899 VQPESEGAEAPEAEKEAQ--PETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQP 1956
Query: 132 QPEVIPLTEDQEEKEGEKAPGE----DTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVND 187
+ EVI E +EE + E E + + E + E+ P+ E Q +
Sbjct: 1957 ESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA 2016
Query: 188 PTESQQEDQLIAGAQDEAKEQRNGTK 213
ES + +EA+E T+
Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQ 2042
Score = 34.3 bits (77), Expect = 0.081
Identities = 29/101 (28%), Positives = 49/101 (48%), Gaps = 12/101 (11%)
Query: 13 EEEDVEMKEDSDENGP---EEKQSVEEMEE---QSQDADGVNTVTV-PGPASEEAVEDCK 65
+EE V+++E + G EE+ +EE+EE + +GV V GP E ++
Sbjct: 1332 QEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGP--EGGLQGEA 1389
Query: 66 DEDFAKDENITKGGEVTDHSVRDQDHPDG---QENDSTKNE 103
E+ K+E + + G V + + PDG QE+D + E
Sbjct: 1390 LEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEE 1430
Score = 27.3 bits (59), Expect = 9.9
Identities = 38/191 (19%), Positives = 69/191 (36%), Gaps = 31/191 (16%)
Query: 7 VDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKD 66
VD+ + E + D D P+ ++ + Q ++ N+ T G EA ++
Sbjct: 1740 VDEGEDGEGSQRLNRDKD---PKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQE--- 1793
Query: 67 EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQED 126
E I++ GE +D+ G+ + +
Sbjct: 1794 -----GEGISERGETGGQGSGHEDNLQGEAAAGGDQD-----------------PGQSDG 1831
Query: 127 AVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVN 186
A +E PE E Q E EG +AP + + E + E+ P+ E +Q + +
Sbjct: 1832 AEGIEAPEAEG--EAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESED 1889
Query: 187 DPT-ESQQEDQ 196
T E++ E Q
Sbjct: 1890 VETPEAEWEVQ 1900
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 48.9 bits (115), Expect = 3e-06
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 20/207 (9%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKD- 66
D +E + +K D +ENG K+S +++ ++S++ G + + +E+ EDC +
Sbjct: 497 DSPKKESKKKTLKNDCEENGLA-KESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEK 555
Query: 67 --EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQ 124
ED ++ E G E +D D +G E + +N + E E S E E +
Sbjct: 556 QSEDGSEREFEENGLE------KDLDE-EGSEKELHENVLDKELEENDS--ENSEFEDDG 606
Query: 125 EDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDK 184
+ V+ E+ ED +EKE E EDT E S + E+ D + DK
Sbjct: 607 SEKVLDEEGSEREFDEDSDEKEEE----EDTYEKVFDDE-SDEKEDEEYADEKGLEAADK 661
Query: 185 VNDPTESQQEDQLIAGAQDEAKEQRNG 211
+ E +++L + D+ E +G
Sbjct: 662 KAE--EGDADEKLFEESDDKEDEDADG 686
Score = 40.8 bits (94), Expect = 9e-04
Identities = 37/194 (19%), Positives = 82/194 (42%), Gaps = 9/194 (4%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDA-------DGVNTVTVPGPASEEA 60
D N E EE+V ++S+E+ E++ + E+QS+D +G+ + +E
Sbjct: 524 DLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKEL 583
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 120
E+ D++ +EN ++ E D +G E + ++ + E E + ++
Sbjct: 584 HENVLDKEL--EENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDE 641
Query: 121 SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNS 180
S +ED ++ + + EE + ++ E++ + ++E+ E +
Sbjct: 642 SDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDD 701
Query: 181 QVDKVNDPTESQQE 194
+K+ D E E
Sbjct: 702 SNEKLFDEEEDSSE 715
Score = 34.7 bits (78), Expect = 0.062
Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 15/111 (13%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVE 62
EF D EEEED K DE+ +EK+ E +E+ +A A ++A E
Sbjct: 619 EFDEDSDEKEEEEDTYEKVFDDES--DEKEDEEYADEKGLEA-----------ADKKAEE 665
Query: 63 DCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSS 113
DE ++ + + + V D D +++DS NE + E SS
Sbjct: 666 GDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDS--NEKLFDEEEDSS 714
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 48.9 bits (115), Expect = 3e-06
Identities = 52/207 (25%), Positives = 91/207 (43%), Gaps = 20/207 (9%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKD- 66
D +E + +K D +ENG K+S +++ ++S++ G + + +E+ EDC +
Sbjct: 497 DSPKKESKKKTLKNDCEENGLA-KESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEK 555
Query: 67 --EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQ 124
ED ++ E G E +D D +G E + +N + E E S E E +
Sbjct: 556 QSEDGSEREFEENGLE------KDLDE-EGSEKELHENVLDKELEENDS--ENSEFEDDG 606
Query: 125 EDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDK 184
+ V+ E+ ED +EKE E EDT E S + E+ D + DK
Sbjct: 607 SEKVLDEEGSEREFDEDSDEKEEE----EDTYEKVFDDE-SDEKEDEEYADEKGLEAADK 661
Query: 185 VNDPTESQQEDQLIAGAQDEAKEQRNG 211
+ E +++L + D+ E +G
Sbjct: 662 KAE--EGDADEKLFEESDDKEDEDADG 686
Score = 40.8 bits (94), Expect = 9e-04
Identities = 37/194 (19%), Positives = 82/194 (42%), Gaps = 9/194 (4%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDA-------DGVNTVTVPGPASEEA 60
D N E EE+V ++S+E+ E++ + E+QS+D +G+ + +E
Sbjct: 524 DLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDLDEEGSEKEL 583
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 120
E+ D++ +EN ++ E D +G E + ++ + E E + ++
Sbjct: 584 HENVLDKEL--EENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDTYEKVFDDE 641
Query: 121 SSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNS 180
S +ED ++ + + EE + ++ E++ + ++E+ E +
Sbjct: 642 SDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDD 701
Query: 181 QVDKVNDPTESQQE 194
+K+ D E E
Sbjct: 702 SNEKLFDEEEDSSE 715
Score = 34.7 bits (78), Expect = 0.062
Identities = 31/111 (27%), Positives = 48/111 (43%), Gaps = 15/111 (13%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVE 62
EF D EEEED K DE+ +EK+ E +E+ +A A ++A E
Sbjct: 619 EFDEDSDEKEEEEDTYEKVFDDES--DEKEDEEYADEKGLEA-----------ADKKAEE 665
Query: 63 DCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSS 113
DE ++ + + + V D D +++DS NE + E SS
Sbjct: 666 GDADEKLFEESDDKEDEDADGKEVEDADEKLFEDDDS--NEKLFDEEEDSS 714
>gi|46409304 glutamate-rich 1 [Homo sapiens]
Length = 443
Score = 48.9 bits (115), Expect = 3e-06
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 14/137 (10%)
Query: 7 VDDNNEE-----EEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAV 61
VD + E+ EEDV+ + D E+ +E+ DA + P PA EE V
Sbjct: 211 VDTSEEDPTLAGEEDVKDTREEDGADASEEDLTRARQEEGADASEED----PTPAGEEDV 266
Query: 62 EDCKDEDFAK--DENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEE 119
+D ++ED +E++T+ GE R++D D E D T E E S E
Sbjct: 267 KDAREEDGVDTIEEDLTRAGEEDGKDTREEDGADASEEDPTWAG---EEEGADSGEEDGA 323
Query: 120 LSSNQEDAVIVEQPEVI 136
+S ++D + E+ I
Sbjct: 324 DASEEDDTITNEKAHSI 340
Score = 34.7 bits (78), Expect = 0.062
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 107 ETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSS 166
E E E + + +++ED + + +V +D E++G A ED R + EG+
Sbjct: 198 EGEGVGEACEEDGVDTSEEDPTLAGEEDV----KDTREEDGADASEEDLTRAR-QEEGAD 252
Query: 167 DLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQD 203
E P P E + + + D ++ +ED AG +D
Sbjct: 253 ASEEDPTPAGEEDVKDAREEDGVDTIEEDLTRAGEED 289
>gi|156104891 general transcription factor IIF, polypeptide 1, 74kDa
[Homo sapiens]
Length = 517
Score = 48.5 bits (114), Expect = 4e-06
Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 18/188 (9%)
Query: 14 EEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDE 73
E+D+EM D+ + EE V + ++++ A G + +EA ED D DF E
Sbjct: 211 EDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQE 270
Query: 74 NITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQP 133
++D S Q+ P+ + + E + QS E E
Sbjct: 271 V----DYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESE-------------- 312
Query: 134 EVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQ 193
E P ED+EE+E +KAP + S SD D E +S + T ++
Sbjct: 313 EEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKR 372
Query: 194 EDQLIAGA 201
E + G+
Sbjct: 373 ERKPSGGS 380
Score = 37.7 bits (86), Expect = 0.007
Identities = 35/163 (21%), Positives = 63/163 (38%), Gaps = 23/163 (14%)
Query: 4 FFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVED 63
F DD + E ++V+ D + EE +S + +Q + GV+ +SEE+ E+
Sbjct: 258 FEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDE---QSDSSEESEEE 314
Query: 64 CKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSN 123
E+ ++E K P QE K ++ +S E ++ S
Sbjct: 315 KPPEEDKEEEEEKKA-------------PTPQEKKRRK-----DSSEESDSSEESDIDSE 356
Query: 124 QEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSS 166
A+ + + + P E + G + G P P GS+
Sbjct: 357 ASSALFMAKKKTPPKRE--RKPSGGSSRGNSRPGTPSAEGGST 397
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 48.1 bits (113), Expect = 5e-06
Identities = 44/191 (23%), Positives = 80/191 (41%), Gaps = 36/191 (18%)
Query: 20 KEDSDENGPEEKQSVEEMEE-QSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKG 78
KEDSDE ++ + EE +E + +D D + + A+ A ED DED DE+
Sbjct: 142 KEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDED---DED---- 194
Query: 79 GEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPEVIPL 138
D+D D +E+D S+ MET + V+ + + +
Sbjct: 195 ---------DEDDDDDEEDD-----------SEEEAMETTPAKGKKAAKVVPVKAKNVAE 234
Query: 139 TEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLI 198
ED+EE + ++ +D E D ++ + E + + V + ++++
Sbjct: 235 DEDEEEDDEDEDDDDD--------EDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAK 286
Query: 199 AGAQDEAKEQR 209
A EAK+Q+
Sbjct: 287 QKAAPEAKKQK 297
Score = 39.7 bits (91), Expect = 0.002
Identities = 30/149 (20%), Positives = 63/149 (42%), Gaps = 15/149 (10%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
D + EE++D E E+ DE+ E++ +E ++ A P E+ +D DE
Sbjct: 144 DSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAA-------APASEDEDDEDDEDDE 196
Query: 68 DFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDA 127
D DE D S + + + ++ ++ + + EE +++D
Sbjct: 197 DDDDDEE--------DDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDD 248
Query: 128 VIVEQPEVIPLTEDQEEKEGEKAPGEDTP 156
+ + +++EE+E E+ P ++ P
Sbjct: 249 DDEDDEDDDDEDDEEEEEEEEEEPVKEAP 277
Score = 37.0 bits (84), Expect = 0.012
Identities = 27/97 (27%), Positives = 48/97 (49%), Gaps = 7/97 (7%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPA-SEEAVEDC 64
S D+++E++ED E +D DE E++++E + + A V V A E+ ED
Sbjct: 184 SEDEDDEDDEDDE-DDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDD 242
Query: 65 KDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTK 101
+DED DE+ + D D++ + +E + K
Sbjct: 243 EDEDDDDDED-----DEDDDDEDDEEEEEEEEEEPVK 274
Score = 30.4 bits (67), Expect = 1.2
Identities = 16/54 (29%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEE 59
+V ++ +EEED E ED D++ +E E+ EE+ ++ + PG +E
Sbjct: 231 NVAEDEDEEEDDE-DEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKE 283
Score = 28.9 bits (63), Expect = 3.4
Identities = 34/163 (20%), Positives = 65/163 (39%), Gaps = 15/163 (9%)
Query: 55 PASEEAVEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETE--SQS 112
P +E ED +DE+ ++DE GE V Q S K + T+ + +
Sbjct: 19 PPPKEVEEDSEDEEMSEDEEDDSSGE---EVVIPQKKGKKAAATSAKKVVVSPTKKVAVA 75
Query: 113 SYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGK------SEGSS 166
+ + ++ ++ A + V P + PG+ PGK ++G+
Sbjct: 76 TPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAK 135
Query: 167 DLENTPGPDVEM----NSQVDKVNDPTESQQEDQLIAGAQDEA 205
+ +N D + +S+ D+ +D E + ED++ A A
Sbjct: 136 NGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAA 178
Score = 28.9 bits (63), Expect = 3.4
Identities = 38/189 (20%), Positives = 69/189 (36%), Gaps = 10/189 (5%)
Query: 12 EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADG--------VNTVTVPGPASEEAVED 63
E+ ED EM ED +++ E+ + + + + A V V PA + AV
Sbjct: 26 EDSEDEEMSEDEEDDSSGEEVVIPQKKGKKAAATSAKKVVVSPTKKVAVATPAKKAAVTP 85
Query: 64 CKDEDFA-KDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSS 122
K + +T VT + K I + + ++ S
Sbjct: 86 GKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDS 145
Query: 123 NQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQV 182
++E+ E+ E ED++E E E A + P SE D ++ D + + +
Sbjct: 146 DEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPA-SEDEDDEDDEDDEDDDDDEED 204
Query: 183 DKVNDPTES 191
D + E+
Sbjct: 205 DSEEEAMET 213
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 48.1 bits (113), Expect = 5e-06
Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 13/202 (6%)
Query: 12 EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAK 71
EEEED K D E G EK+ E EE Q+ +G G + EA E+ K E+
Sbjct: 536 EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE-EGETEAEAEGEEA-EAKEEKKVEE-KS 592
Query: 72 DENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVE 131
+E TK V D V + P+ ++ K+ ++ + +S EE + VE
Sbjct: 593 EEVATKEELVADAKV---EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 649
Query: 132 QPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTES 191
+ P+ + E++G K+P + P + + S + +P + + ++V K +
Sbjct: 650 EKGKSPVPKSPVEEKG-KSP---VSKSPVEEKAKSPVPKSPVEEAKSKAEVGK---GEQK 702
Query: 192 QQEDQLIAGAQDEAKEQRNGTK 213
++E++ + A E K ++ K
Sbjct: 703 EEEEKEVKEAPKEEKVEKKEEK 724
Score = 47.4 bits (111), Expect = 9e-06
Identities = 50/219 (22%), Positives = 93/219 (42%), Gaps = 26/219 (11%)
Query: 13 EEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA--------VEDC 64
EE V MKE+ E E+++ E EE+ T P EE E+
Sbjct: 478 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE 537
Query: 65 KDEDFAKDENITKGG-EVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSN 123
++++ AK + +GG E S +++ + E ++ + E + + E E +
Sbjct: 538 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 597
Query: 124 QEDAVI---VEQPEVI--PLTEDQEEKEGE----KAPGED-----TPRMPGKSEGSSDLE 169
+E+ V VE+PE P+ + E++G+ K+P E+ P+ P + +G S +
Sbjct: 598 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 657
Query: 170 NTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQ 208
+P VE + P E + + + +EAK +
Sbjct: 658 KSP---VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSK 693
Score = 35.0 bits (79), Expect = 0.047
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
Query: 104 IKIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSE 163
+ ++ E + + E EE +E+ V ++ V + +E+EGEK E + E
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 541
Query: 164 GS-SDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQR 209
G+ SD G + E +S +K E + + G + EAKE++
Sbjct: 542 GAKSDQAEEGGSEKEGSS--EKEEGEQEEGETEAEAEGEEAEAKEEK 586
Score = 34.3 bits (77), Expect = 0.081
Identities = 30/138 (21%), Positives = 64/138 (46%), Gaps = 3/138 (2%)
Query: 13 EEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKD 72
+EE VE KE+ ++ PE+K++ ++E++ T +V +E E+ K K+
Sbjct: 714 KEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 773
Query: 73 ENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQ 132
+ G ++ D+ ++ D N ++E + + E+ S +E+ +V
Sbjct: 774 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG-EVEGKEEVEQETKEKGSGREEEKGVVTN 832
Query: 133 PEVIPLTEDQEEKEGEKA 150
+ L+ E+K G+K+
Sbjct: 833 G--LDLSPADEKKGGDKS 848
Score = 32.0 bits (71), Expect = 0.40
Identities = 48/228 (21%), Positives = 95/228 (41%), Gaps = 34/228 (14%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEE-------MEEQSQDADGVNTVTVPGPASEEA 60
++ +EE + E + + +E +E++ VEE EE DA P +
Sbjct: 562 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 621
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQ-------DHPDGQENDSTKNEIKIETESQSS 113
VE+ K KG S ++ P ++ S ++ +E +++S
Sbjct: 622 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSP 681
Query: 114 YMET--EELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPR--------MPGKSE 163
++ EE S E V + E +++EEKE ++AP E+ +P K +
Sbjct: 682 VPKSPVEEAKSKAE----VGKGE----QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKK 733
Query: 164 GSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRNG 211
S ++ +V ++ KV+ E+++E + + Q++ KE+ G
Sbjct: 734 AESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL--QQEKEKEKAGG 779
Score = 31.2 bits (69), Expect = 0.68
Identities = 41/197 (20%), Positives = 77/197 (39%), Gaps = 26/197 (13%)
Query: 20 KEDSDENG--PEEKQSVEEMEEQ---SQDADGVNTVTVPGPASEEAVEDCKDEDFAKDEN 74
K +E G P K VEE + + + G ++ E+ + ++ K+E
Sbjct: 658 KSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 717
Query: 75 ITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPE 134
+ K E V ++ + + E+ T+S ++E E +
Sbjct: 718 VEKKEE-KPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGK---------- 766
Query: 135 VIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQE 194
PL Q+EKE EKA GE G +G+ + + D+ +N +V+ + + +E
Sbjct: 767 --PL---QQEKEKEKAGGEGGSEEEGSDKGA---KGSRKEDIAVNGEVEGKEEVEQETKE 818
Query: 195 DQLIAGAQDEAKEQRNG 211
+G ++E NG
Sbjct: 819 KG--SGREEEKGVVTNG 833
Score = 30.0 bits (66), Expect = 1.5
Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 21/159 (13%)
Query: 58 EEAVEDCK--DEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYM 115
EE +E+ K DE +E +T E S++++ +E + E E++
Sbjct: 454 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEE-------EPEAE---- 502
Query: 116 ETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGED------TPRMPGKSEGSSDLE 169
EE + ++ V PEV ++EE+EG++ E+ G SE E
Sbjct: 503 --EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 560
Query: 170 NTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQ 208
G E ++ + + E+++E ++ +++ A ++
Sbjct: 561 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 599
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 48.1 bits (113), Expect = 5e-06
Identities = 50/202 (24%), Positives = 90/202 (44%), Gaps = 13/202 (6%)
Query: 12 EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAK 71
EEEED K D E G EK+ E EE Q+ +G G + EA E+ K E+
Sbjct: 160 EEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQE-EGETEAEAEGEEA-EAKEEKKVEE-KS 216
Query: 72 DENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVE 131
+E TK V D V + P+ ++ K+ ++ + +S EE + VE
Sbjct: 217 EEVATKEELVADAKV---EKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVE 273
Query: 132 QPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTES 191
+ P+ + E++G K+P + P + + S + +P + + ++V K +
Sbjct: 274 EKGKSPVPKSPVEEKG-KSP---VSKSPVEEKAKSPVPKSPVEEAKSKAEVGK---GEQK 326
Query: 192 QQEDQLIAGAQDEAKEQRNGTK 213
++E++ + A E K ++ K
Sbjct: 327 EEEEKEVKEAPKEEKVEKKEEK 348
Score = 47.4 bits (111), Expect = 9e-06
Identities = 50/219 (22%), Positives = 93/219 (42%), Gaps = 26/219 (11%)
Query: 13 EEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA--------VEDC 64
EE V MKE+ E E+++ E EE+ T P EE E+
Sbjct: 102 EELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEE 161
Query: 65 KDEDFAKDENITKGG-EVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSN 123
++++ AK + +GG E S +++ + E ++ + E + + E E +
Sbjct: 162 EEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 221
Query: 124 QEDAVI---VEQPEVI--PLTEDQEEKEGE----KAPGED-----TPRMPGKSEGSSDLE 169
+E+ V VE+PE P+ + E++G+ K+P E+ P+ P + +G S +
Sbjct: 222 KEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVP 281
Query: 170 NTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQ 208
+P VE + P E + + + +EAK +
Sbjct: 282 KSP---VEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSK 317
Score = 35.0 bits (79), Expect = 0.047
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 3/107 (2%)
Query: 104 IKIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSE 163
+ ++ E + + E EE +E+ V ++ V + +E+EGEK E + E
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDE 165
Query: 164 GS-SDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQR 209
G+ SD G + E +S +K E + + G + EAKE++
Sbjct: 166 GAKSDQAEEGGSEKEGSS--EKEEGEQEEGETEAEAEGEEAEAKEEK 210
Score = 34.3 bits (77), Expect = 0.081
Identities = 30/138 (21%), Positives = 64/138 (46%), Gaps = 3/138 (2%)
Query: 13 EEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKD 72
+EE VE KE+ ++ PE+K++ ++E++ T +V +E E+ K K+
Sbjct: 338 KEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKE 397
Query: 73 ENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQ 132
+ G ++ D+ ++ D N ++E + + E+ S +E+ +V
Sbjct: 398 KEKAGGEGGSEEEGSDKGAKGSRKEDIAVNG-EVEGKEEVEQETKEKGSGREEEKGVVTN 456
Query: 133 PEVIPLTEDQEEKEGEKA 150
+ L+ E+K G+K+
Sbjct: 457 G--LDLSPADEKKGGDKS 472
Score = 32.0 bits (71), Expect = 0.40
Identities = 48/228 (21%), Positives = 95/228 (41%), Gaps = 34/228 (14%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEE-------MEEQSQDADGVNTVTVPGPASEEA 60
++ +EE + E + + +E +E++ VEE EE DA P +
Sbjct: 186 EEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSP 245
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQ-------DHPDGQENDSTKNEIKIETESQSS 113
VE+ K KG S ++ P ++ S ++ +E +++S
Sbjct: 246 VEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSP 305
Query: 114 YMET--EELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPR--------MPGKSE 163
++ EE S E V + E +++EEKE ++AP E+ +P K +
Sbjct: 306 VPKSPVEEAKSKAE----VGKGE----QKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKK 357
Query: 164 GSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRNG 211
S ++ +V ++ KV+ E+++E + + Q++ KE+ G
Sbjct: 358 AESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPL--QQEKEKEKAGG 403
Score = 31.2 bits (69), Expect = 0.68
Identities = 41/197 (20%), Positives = 77/197 (39%), Gaps = 26/197 (13%)
Query: 20 KEDSDENG--PEEKQSVEEMEEQ---SQDADGVNTVTVPGPASEEAVEDCKDEDFAKDEN 74
K +E G P K VEE + + + G ++ E+ + ++ K+E
Sbjct: 282 KSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK 341
Query: 75 ITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPE 134
+ K E V ++ + + E+ T+S ++E E +
Sbjct: 342 VEKKEE-KPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGK---------- 390
Query: 135 VIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQE 194
PL Q+EKE EKA GE G +G+ + + D+ +N +V+ + + +E
Sbjct: 391 --PL---QQEKEKEKAGGEGGSEEEGSDKGA---KGSRKEDIAVNGEVEGKEEVEQETKE 442
Query: 195 DQLIAGAQDEAKEQRNG 211
+G ++E NG
Sbjct: 443 KG--SGREEEKGVVTNG 457
Score = 30.0 bits (66), Expect = 1.5
Identities = 33/159 (20%), Positives = 68/159 (42%), Gaps = 21/159 (13%)
Query: 58 EEAVEDCK--DEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYM 115
EE +E+ K DE +E +T E S++++ +E + E E++
Sbjct: 78 EEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEE-------EPEAE---- 126
Query: 116 ETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGED------TPRMPGKSEGSSDLE 169
EE + ++ V PEV ++EE+EG++ E+ G SE E
Sbjct: 127 --EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSE 184
Query: 170 NTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQ 208
G E ++ + + E+++E ++ +++ A ++
Sbjct: 185 KEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 223
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 47.4 bits (111), Expect = 9e-06
Identities = 50/217 (23%), Positives = 94/217 (43%), Gaps = 23/217 (10%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDA--DGVNTVTVPGPASEEA-VEDC 64
DDN+++ E + ++SD++ + S + ++ S D+ D + VP S+++ V D
Sbjct: 170 DDNSDDSEAPD--DNSDDSDVPDDNSDDSSDDNSDDSSDDNSDDSDVPDDKSDDSDVPDD 227
Query: 65 KDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDS-TKNEIKIETESQSSYMETEELSSN 123
+D ++ + E D S D + PD +DS ++ ++E+ + E S +
Sbjct: 228 SSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPDDSSDDSEASDD 287
Query: 124 QEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQV- 182
D E + D E +K+ D P KS+ SD+ + D+E+
Sbjct: 288 SSD-----DSEASDDSSDDSEAPDDKSDDSDVPE--DKSD-DSDVPDDNSDDLEVPVPAE 339
Query: 183 DKVNDPTESQQEDQLIAGA--------QDEAKEQRNG 211
D N+ + E++L+ A D+A EQ G
Sbjct: 340 DLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLG 376
Score = 46.6 bits (109), Expect = 2e-05
Identities = 44/206 (21%), Positives = 90/206 (43%), Gaps = 14/206 (6%)
Query: 11 NEEEEDVEMKEDSDENGPE---EKQSVEE----MEEQSQDADGVNTVTVPGPASE--EAV 61
+EE++ ++ +SD+ PE K +++E + + D D N + VP S+ EA
Sbjct: 90 HEEKKAKLLEINSDDESPECCHVKPAIQEPPIVISDDDNDDDNGNDLEVPDDNSDDSEAP 149
Query: 62 EDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELS 121
+D D+ A D+N + E D + D + PD +DS + + S + ++ + +
Sbjct: 150 DDNSDDSEAPDDN-SDDSEAPDDNSDDSEAPDDNSDDSDVPDDNSDDSSDDNSDDSSDDN 208
Query: 122 SNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQ 181
S+ D V ++ + + +D + D P + SSD P + +
Sbjct: 209 SDDSD-VPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAP---DDSSDDSEAPDDSSDDSEA 264
Query: 182 VDKVNDPTESQQEDQLIAGAQDEAKE 207
D +D +E+ + + A D++ +
Sbjct: 265 PDDSSDDSEAPDDSSDDSEASDDSSD 290
Score = 45.4 bits (106), Expect = 4e-05
Identities = 53/226 (23%), Positives = 93/226 (41%), Gaps = 39/226 (17%)
Query: 6 SVDDNNEE-------EEDVEMKEDS--DENGPEEKQSVEEMEEQSQD-----ADGVNTVT 51
S DDN+++ +D ++ +DS D + P++ E + S D D +
Sbjct: 204 SSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 263
Query: 52 VPGPASE--EAVEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIE-- 107
P +S+ EA +D D+ A D++ + E +D S D + PD + +DS E K +
Sbjct: 264 APDDSSDDSEAPDDSSDDSEASDDS-SDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDS 322
Query: 108 --TESQSSYMETE----------ELSSNQED----AVIVEQPEVIPLTEDQEEKEGEKAP 151
+ S +E +++S++E+ A V Q + +Q+ E P
Sbjct: 323 DVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVEAAAAVSQHDSSDDAGEQDLGENLSKP 382
Query: 152 GEDTPRMPGKSEGSSDLENTPGPDVEMN----SQVDKVNDPTESQQ 193
D P SE E P P VE + S+ + +P +Q
Sbjct: 383 PSDPEANPEVSERKLPTEEEPAPVVEQSGKRKSKTKTIVEPPRKRQ 428
Score = 44.3 bits (103), Expect = 8e-05
Identities = 47/214 (21%), Positives = 86/214 (40%), Gaps = 21/214 (9%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKD- 66
DDN+++ E + D E + E ++ S D+D VP S+++ +D D
Sbjct: 150 DDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSD------VPDDNSDDSSDDNSDD 203
Query: 67 --EDFAKDENI----TKGGEVTDHSVRDQDHPDGQENDS----TKNEIKIETESQSSYME 116
+D + D ++ + +V D S D D PD +DS ++ + S E
Sbjct: 204 SSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSE 263
Query: 117 TEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDV 176
+ SS+ +A + + ++ E +D+ KS+ SD+ D
Sbjct: 264 APDDSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSD-DSDVPEDKSDDS 322
Query: 177 EM---NSQVDKVNDPTESQQEDQLIAGAQDEAKE 207
++ NS +V P E + IA ++E E
Sbjct: 323 DVPDDNSDDLEVPVPAEDLCNEGQIASDEEELVE 356
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 47.4 bits (111), Expect = 9e-06
Identities = 45/210 (21%), Positives = 82/210 (39%), Gaps = 20/210 (9%)
Query: 9 DNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCK--D 66
+ EEEE+ E +E+ +E G EE E +D DG + P ED D
Sbjct: 1351 EEEEEEEEEEEEEEEEEEGEEE----EGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLD 1406
Query: 67 EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIET-----ESQSSYMETEELS 121
+ ++E + DH D+D + + K E+ E+ E+Q ++++
Sbjct: 1407 DHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFLDLNVQP 1466
Query: 122 SNQEDAVIVEQPEVIPLTEDQEEKE----GEKAPGEDTPRMPGKSEGSSDLENTPGPDVE 177
+ V+++ + + + E KE E P D PG+ D +N+ D E
Sbjct: 1467 GHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTE 1526
Query: 178 MNSQVDKVNDPTESQQEDQLIAGAQDEAKE 207
K +P + + + + Q +E
Sbjct: 1527 F-----KEGNPATMEIDSETVQAVQSLTQE 1551
Score = 37.4 bits (85), Expect = 0.010
Identities = 41/170 (24%), Positives = 75/170 (44%), Gaps = 11/170 (6%)
Query: 28 PEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKGGEVTDHSVR 87
P+E+ +VEE +E S+ + + + EE V++ + ++EN E T V
Sbjct: 1283 PDEQVTVEEQKETSEGKTSPSPIRI-----EEEVKETGEALLPQEEN---RREETCAPVS 1334
Query: 88 DQDHP-DGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKE 146
P + E+D K E + E E + E EE +E VE+ ++++EE E
Sbjct: 1335 PNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPE 1394
Query: 147 GEKAPGEDTPRMPG-KSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQED 195
ED+ R+ + E D E + D + + + D + E ++E+
Sbjct: 1395 -ISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEE 1443
Score = 36.6 bits (83), Expect = 0.016
Identities = 28/144 (19%), Positives = 63/144 (43%), Gaps = 22/144 (15%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
S + + EEEE+ + +E+ +E EE + EE EE+ ++ + + + + P ++V +
Sbjct: 1065 SKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQS-SPPRLTKPQSVAIKR 1123
Query: 66 DEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQE 125
F + G++ + + ET S+++ + E ++ E
Sbjct: 1124 KRPFVLKKK------------------RGRKRRRINSSVTTETISETTEVLNEPFDNSDE 1165
Query: 126 DAVIVEQPEVIPLTEDQEEKEGEK 149
+ P++ P E + E++G K
Sbjct: 1166 ER---PMPQLEPTCEIEVEEDGRK 1186
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 47.0 bits (110), Expect = 1e-05
Identities = 46/214 (21%), Positives = 84/214 (39%), Gaps = 18/214 (8%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
D EEE++ E KE+ + E ++ EE E + ++ G G + E ++E
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEE---KGEEEGDQGEGEEEE 800
Query: 68 DFAKDENITKGGEVTDHSVRD---------------QDHPDGQENDSTKNEIKIETESQS 112
+ E +GGEV V + ++ +G+E + E + E + +
Sbjct: 801 TEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEE 860
Query: 113 SYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTP 172
E E +E E+ E E++ E EGE+ GE G+ EG +
Sbjct: 861 EGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGK 920
Query: 173 GPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAK 206
G + + + + E + ED G ++E +
Sbjct: 921 GEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGE 954
Score = 45.4 bits (106), Expect = 4e-05
Identities = 46/217 (21%), Positives = 86/217 (39%), Gaps = 17/217 (7%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
++ EEE+ E +E+ E EE+ E EE+ ++ +G EE E +E
Sbjct: 838 EEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE 897
Query: 68 DFAKDENITKG-GEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQED 126
+ + E +G GE + + +G+E + E + E E + E EE E
Sbjct: 898 EEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEG 957
Query: 127 AVIVEQPEVIPL------------TEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGP 174
+ E E++ E EGE+ GE+ G+ E + E
Sbjct: 958 EEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Query: 175 DVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRNG 211
+ E+ +V+ E ++E+ G ++ + ++ G
Sbjct: 1018 EGEVEGEVEGEEGEGEGEEEE----GEEEGEEREKEG 1050
Score = 43.1 bits (100), Expect = 2e-04
Identities = 44/202 (21%), Positives = 85/202 (42%), Gaps = 20/202 (9%)
Query: 13 EEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKD 72
++ D E +E + +K+ +EMEE ++ G EE D ++E+ +
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHG---------EGEEEEGDREEEEEKEG 753
Query: 73 ENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETES---QSSYMETEELSSNQEDAVI 129
E +G R+++ + ++ + E K E E + ETE +E+
Sbjct: 754 EGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGE 813
Query: 130 VEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPT 189
VE EV ++EE+E E+ GE+ EG + E G + E + ++ +
Sbjct: 814 VEGGEVEEGKGEREEEE-EEGEGEE-------EEGEGEEEEGEGEEEEGEGKGEEEGEEG 865
Query: 190 ESQQEDQLIAGAQDEAKEQRNG 211
E ++E + G +E + + G
Sbjct: 866 EGEEEGEEGEGEGEEEEGEGEG 887
Score = 42.7 bits (99), Expect = 2e-04
Identities = 40/205 (19%), Positives = 89/205 (43%), Gaps = 22/205 (10%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
D+ E+ E + + + + G EK+ E+ E + +D + +E E +
Sbjct: 671 DEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGE-----------EQEQKEREQGH 719
Query: 68 DFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDA 127
+++ + +GGE ++H +G+E + + E + + E EE+ +E
Sbjct: 720 QKERNQEMEEGGE--------EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKE 771
Query: 128 VIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVND 187
+ E E++ E+EG++ GE+ G+ E + G +VE + ++ +
Sbjct: 772 EGERKKEERAGKEEKGEEEGDQGEGEE-EETEGRGEEKEEGGEVEGGEVE-EGKGEREEE 829
Query: 188 PTESQQEDQLIAGAQDEAK-EQRNG 211
E + E++ G ++E + E+ G
Sbjct: 830 EEEGEGEEEEGEGEEEEGEGEEEEG 854
Score = 42.7 bits (99), Expect = 2e-04
Identities = 44/171 (25%), Positives = 80/171 (46%), Gaps = 16/171 (9%)
Query: 8 DDNNEEEEDVEMKEDSDE-NGPEEKQSVEEMEEQSQDADGVNT---VTVPGPASEEAVED 63
+ +++E + EM+E +E +G E++ + EE+ ++ +G V G +E E
Sbjct: 716 EQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGER 775
Query: 64 CKDEDFAKDENITKGGEVTDHSVRDQDHPDGQ-ENDSTKNEIK---IETESQSSYMETEE 119
K+E K+E KG E D +++ +G+ E E++ +E E + E EE
Sbjct: 776 KKEERAGKEE---KGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVE-EGKGEREEEEE 831
Query: 120 LSSNQEDAVIVEQPEVIPLTEDQE---EKEGEKAPGEDTPRMPGKSEGSSD 167
+E+ E+ E E+ E E+EGE+ GE+ G+ EG +
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGE-EGEGEGEEE 881
Score = 41.6 bits (96), Expect = 5e-04
Identities = 46/211 (21%), Positives = 81/211 (38%), Gaps = 12/211 (5%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEE---MEEQSQDADGVNTVTVPGPASEEAVEDC 64
DD++E EE EMKE G KQ V + M + + + + V P +E ED
Sbjct: 542 DDSDEYEEMSEMKE-----GKACKQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDS 596
Query: 65 KDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQ 124
K + E V H R + +D ++ ++ S E E+ +
Sbjct: 597 KGNGIEEQEVEANEENVKVHGGRKEKTEI--LSDDLTDKAEVSEGKAKSVGEAEDGPEGR 654
Query: 125 EDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGS-SDLENTPGPDVEMNSQVD 183
D E +D+E ++GEK G PG+ E ++ E D E Q +
Sbjct: 655 GDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKE 714
Query: 184 KVNDPTESQQEDQLIAGAQDEAK-EQRNGTK 213
+ + + ++ G ++ + E+ G +
Sbjct: 715 REQGHQKERNQEMEEGGEEEHGEGEEEEGDR 745
Score = 41.2 bits (95), Expect = 7e-04
Identities = 38/158 (24%), Positives = 67/158 (42%), Gaps = 6/158 (3%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
D E EE+ E +E G E + E E + + +G EE E+ ++E
Sbjct: 943 DGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Query: 68 DFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDA 127
++E +G E + V + + E + + E + E E + E EE N+E
Sbjct: 1003 GEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNRE-- 1060
Query: 128 VIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGS 165
E+ E ++ E+E E+ GE+ ++ K +GS
Sbjct: 1061 ---EEEEEEGKYQETGEEENERQDGEEYKKV-SKIKGS 1094
Score = 40.4 bits (93), Expect = 0.001
Identities = 46/206 (22%), Positives = 83/206 (40%), Gaps = 23/206 (11%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
+ EEEE E+ E EE++ + EE+ ++ +G G E E E
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEG------EGEEEEGEGEGEDGE 945
Query: 68 DFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDA 127
++E GE + ++ +G+ + + E E + E EE +E+
Sbjct: 946 GEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEE--EGEEEG 1003
Query: 128 VIVEQPEVIPLTEDQEEKEGE---KAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDK 184
E+ E E +EE+EGE + GE+ G+ EG + G + E + ++
Sbjct: 1004 EGEEEGE----GEGEEEEEGEVEGEVEGEE-----GEGEGEEEEGEEEGEEREKEGEGEE 1054
Query: 185 VNDPTESQQEDQLIAGAQDEAKEQRN 210
E ++E++ G E E+ N
Sbjct: 1055 NRRNREEEEEEE---GKYQETGEEEN 1077
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 46.6 bits (109), Expect = 2e-05
Identities = 44/218 (20%), Positives = 80/218 (36%), Gaps = 26/218 (11%)
Query: 7 VDDNNEEEEDVEMKEDSDENG---------PEEKQSVEEMEEQSQDADGVNTVTVPGPAS 57
+DDNN EE +K DS EN P + E+ ++ + V GP+S
Sbjct: 282 LDDNNTMEE---VKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 338
Query: 58 EEAVE--------DCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETE 109
E + E + ++ E+ + T V DQ+ D E DS+ ++E
Sbjct: 339 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 398
Query: 110 SQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLE 169
S+ ++E S E P ED+ E + E S+ +
Sbjct: 399 SREEQADSESSESLNFSEESPESP------EDENSSSQEGLQSHSSSAESQSEESHSEED 452
Query: 170 NTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKE 207
++ D + + + S +ED + + E+++
Sbjct: 453 DSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 490
Score = 38.9 bits (89), Expect = 0.003
Identities = 50/236 (21%), Positives = 97/236 (41%), Gaps = 28/236 (11%)
Query: 2 NEFFSVDDNN----EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPAS 57
++ F DD+ + +E + SDE+ + Q+ EE Q QD+ T +
Sbjct: 111 DDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDN 170
Query: 58 EEAVEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQEND----------STKNEIKIE 107
E+ V+ + + E+ ++ V S + H DG E D S ++E +
Sbjct: 171 EDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSE-RGN 229
Query: 108 TESQSSYMETEELSSNQEDA--------VIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMP 159
+ S+ M+++E N E A ++E P + + +E +++ +D M
Sbjct: 230 SRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTME 289
Query: 160 GKSEGSSDLENTPGPDVEM---NSQVDKVNDPTE--SQQEDQLIAGAQDEAKEQRN 210
S++ N+ + +S+ D D E SQ+E Q + G E+ ++ N
Sbjct: 290 EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEAN 345
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 46.6 bits (109), Expect = 2e-05
Identities = 44/218 (20%), Positives = 80/218 (36%), Gaps = 26/218 (11%)
Query: 7 VDDNNEEEEDVEMKEDSDENG---------PEEKQSVEEMEEQSQDADGVNTVTVPGPAS 57
+DDNN EE +K DS EN P + E+ ++ + V GP+S
Sbjct: 266 LDDNNTMEE---VKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSS 322
Query: 58 EEAVE--------DCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETE 109
E + E + ++ E+ + T V DQ+ D E DS+ ++E
Sbjct: 323 ESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSE 382
Query: 110 SQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLE 169
S+ ++E S E P ED+ E + E S+ +
Sbjct: 383 SREEQADSESSESLNFSEESPESP------EDENSSSQEGLQSHSSSAESQSEESHSEED 436
Query: 170 NTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKE 207
++ D + + + S +ED + + E+++
Sbjct: 437 DSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIEIESRK 474
Score = 38.9 bits (89), Expect = 0.003
Identities = 50/236 (21%), Positives = 97/236 (41%), Gaps = 28/236 (11%)
Query: 2 NEFFSVDDNN----EEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPAS 57
++ F DD+ + +E + SDE+ + Q+ EE Q QD+ T +
Sbjct: 95 DDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDN 154
Query: 58 EEAVEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQEND----------STKNEIKIE 107
E+ V+ + + E+ ++ V S + H DG E D S ++E +
Sbjct: 155 EDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSE-RGN 213
Query: 108 TESQSSYMETEELSSNQEDA--------VIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMP 159
+ S+ M+++E N E A ++E P + + +E +++ +D M
Sbjct: 214 SRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTME 273
Query: 160 GKSEGSSDLENTPGPDVEM---NSQVDKVNDPTE--SQQEDQLIAGAQDEAKEQRN 210
S++ N+ + +S+ D D E SQ+E Q + G E+ ++ N
Sbjct: 274 EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEAN 329
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 46.6 bits (109), Expect = 2e-05
Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 18/135 (13%)
Query: 11 NEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFA 70
+EEEE+ E +E+ + + EE + EE EE+ ++ G N+ ASE++ E+ +E+ +
Sbjct: 278 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS----EEASEQSAEEVSEEEMS 333
Query: 71 KDENITKGGE--VTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAV 128
+DE V S D+D + +E + E T + S+ E
Sbjct: 334 EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE------------GTPQSSALTEGDY 381
Query: 129 IVEQPEVIPLTEDQE 143
+ + P ++P+ QE
Sbjct: 382 VPDSPALLPIELKQE 396
Score = 42.4 bits (98), Expect = 3e-04
Identities = 29/140 (20%), Positives = 59/140 (42%), Gaps = 12/140 (8%)
Query: 1 MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA 60
+++ + D+ + E +G EE++ EE EE+ G SEE+
Sbjct: 251 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE------------GSTSEES 298
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 120
E+ ++E+ ++E + E ++ S + + E++ +NE + +S +
Sbjct: 299 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 358
Query: 121 SSNQEDAVIVEQPEVIPLTE 140
S E+ V P+ LTE
Sbjct: 359 SEEAEEEVGEGTPQSSALTE 378
Score = 42.0 bits (97), Expect = 4e-04
Identities = 36/185 (19%), Positives = 83/185 (44%), Gaps = 17/185 (9%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVE 62
E F + D + ++ +M+E + + Q + + E ++ A+ + + G EE E
Sbjct: 229 ERFELGDGRKPVKEEKMEE---RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 285
Query: 63 DCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSS 122
+ ++E+ G ++ S +++ + +E ++ N + +S E EE+S
Sbjct: 286 EEEEEE----------GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-EEMSE 334
Query: 123 NQE---DAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMN 179
++E + ++ PE + E +E E+ GE TP+ +EG ++ +E+
Sbjct: 335 DEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELK 394
Query: 180 SQVDK 184
++ K
Sbjct: 395 QELPK 399
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 46.6 bits (109), Expect = 2e-05
Identities = 34/135 (25%), Positives = 63/135 (46%), Gaps = 18/135 (13%)
Query: 11 NEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFA 70
+EEEE+ E +E+ + + EE + EE EE+ ++ G N+ ASE++ E+ +E+ +
Sbjct: 288 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS----EEASEQSAEEVSEEEMS 343
Query: 71 KDENITKGGE--VTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAV 128
+DE V S D+D + +E + E T + S+ E
Sbjct: 344 EDEERENENHLLVVPESRFDRDSGESEEAEEEVGE------------GTPQSSALTEGDY 391
Query: 129 IVEQPEVIPLTEDQE 143
+ + P ++P+ QE
Sbjct: 392 VPDSPALLPIELKQE 406
Score = 42.4 bits (98), Expect = 3e-04
Identities = 29/140 (20%), Positives = 59/140 (42%), Gaps = 12/140 (8%)
Query: 1 MNEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA 60
+++ + D+ + E +G EE++ EE EE+ G SEE+
Sbjct: 261 LSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE------------GSTSEES 308
Query: 61 VEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEEL 120
E+ ++E+ ++E + E ++ S + + E++ +NE + +S +
Sbjct: 309 EEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGE 368
Query: 121 SSNQEDAVIVEQPEVIPLTE 140
S E+ V P+ LTE
Sbjct: 369 SEEAEEEVGEGTPQSSALTE 388
Score = 42.0 bits (97), Expect = 4e-04
Identities = 36/185 (19%), Positives = 83/185 (44%), Gaps = 17/185 (9%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVE 62
E F + D + ++ +M+E + + Q + + E ++ A+ + + G EE E
Sbjct: 239 ERFELGDGRKPVKEEKMEE---RDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEE 295
Query: 63 DCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSS 122
+ ++E+ G ++ S +++ + +E ++ N + +S E EE+S
Sbjct: 296 EEEEEE----------GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSE-EEMSE 344
Query: 123 NQE---DAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMN 179
++E + ++ PE + E +E E+ GE TP+ +EG ++ +E+
Sbjct: 345 DEERENENHLLVVPESRFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELK 404
Query: 180 SQVDK 184
++ K
Sbjct: 405 QELPK 409
>gi|218505787 protocadherin 15 isoform CD2-1 precursor [Homo sapiens]
Length = 1790
Score = 46.6 bits (109), Expect = 2e-05
Identities = 43/197 (21%), Positives = 84/197 (42%), Gaps = 26/197 (13%)
Query: 24 DENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKGGEVTD 83
D G E ++ +EE +D D + A+E VE ++ +D
Sbjct: 1569 DLEGEEWQRRLEE-----EDKDYLKLTLDQEEATESTVESEEESS-------------SD 1610
Query: 84 HSVRDQDHPDGQENDSTKNEIKIET---ESQSSYMETEELSSNQEDAVIVEQPEVI---- 136
++ ++ + E+++T+ E + ET E +SS E+EE S + + + V+
Sbjct: 1611 YTEYSEEESEFSESETTEEESESETPSEEEESSTPESEESESTESEGEKARKNIVLARRR 1670
Query: 137 PLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGP-DVEMNSQVDKVNDPTESQQED 195
P+ E+ +E +G K ++ + P E E GP VE ++ + + P E E
Sbjct: 1671 PMVEEVKEVKGRKEEPQEEQKEPKMEEEEHSEEEESGPAPVEESTDPEAQDIPEEGSAES 1730
Query: 196 QLIAGAQDEAKEQRNGT 212
+ G + +E +G+
Sbjct: 1731 ASVEGGVESEEESESGS 1747
Score = 38.1 bits (87), Expect = 0.006
Identities = 47/214 (21%), Positives = 87/214 (40%), Gaps = 20/214 (9%)
Query: 15 EDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDED-----F 69
E E E+ +E + K+ E+ E S++ + V T+ P PA+E K F
Sbjct: 1497 EAEEEYEEEEEEPKKIKKPKVEIREPSEEEEVVVTIEKP-PAAEPTYTTWKRARIFPMIF 1555
Query: 70 AKDENITKG-------GEVTDHSVRDQDHP----DGQENDSTKNEIKIETESQSSYME-T 117
K + GE + ++D + ++T++ ++ E ES S Y E +
Sbjct: 1556 KKVRGLADKRGIVDLEGEEWQRRLEEEDKDYLKLTLDQEEATESTVESEEESSSDYTEYS 1615
Query: 118 EELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVE 177
EE S E E+ E +E++E E E T K+ + L E
Sbjct: 1616 EEESEFSESETTEEESESETPSEEEESSTPESEESESTESEGEKARKNIVLARRRPMVEE 1675
Query: 178 MNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRNG 211
+ + +P E Q+E ++ ++ ++E+ +G
Sbjct: 1676 VKEVKGRKEEPQEEQKEPKM--EEEEHSEEEESG 1707
Score = 32.0 bits (71), Expect = 0.40
Identities = 35/169 (20%), Positives = 65/169 (38%), Gaps = 19/169 (11%)
Query: 2 NEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAV 61
+EF + EE E E+ + + PE ++S E E + + A + P EE
Sbjct: 1619 SEFSESETTEEESESETPSEEEESSTPESEES-ESTESEGEKARKNIVLARRRPMVEEVK 1677
Query: 62 EDCKDEDFAKDENITKGGEVTDHSVRD---------------QDHPDGQENDSTKNEIKI 106
E ++ ++E E +HS + QD P+ +S E +
Sbjct: 1678 EVKGRKEEPQEEQKEPKMEEEEHSEEEESGPAPVEESTDPEAQDIPEEGSAESASVEGGV 1737
Query: 107 ETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDT 155
E+E +S + S +Q Q +P + + +K+PG ++
Sbjct: 1738 ESEEESESGSSSSSSESQSGGPWGYQ---VPAYDRSKNANQKKSPGANS 1783
Score = 29.3 bits (64), Expect = 2.6
Identities = 37/158 (23%), Positives = 56/158 (35%), Gaps = 15/158 (9%)
Query: 11 NEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFA 70
+EEE + E S+E + E E +S+ P+ EE E E
Sbjct: 1603 SEEESSSDYTEYSEEESEFSESETTEEESESET-----------PSEEE--ESSTPESEE 1649
Query: 71 KDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSS-YMETEELSSNQEDAVI 129
+ ++G + + V + P +E K + E Q ME EE S +E
Sbjct: 1650 SESTESEGEKARKNIVLARRRPMVEEVKEVKGRKEEPQEEQKEPKMEEEEHSEEEESGPA 1709
Query: 130 VEQPEVIPLTED-QEEKEGEKAPGEDTPRMPGKSEGSS 166
+ P +D EE E A E +SE S
Sbjct: 1710 PVEESTDPEAQDIPEEGSAESASVEGGVESEEESESGS 1747
Score = 28.9 bits (63), Expect = 3.4
Identities = 33/176 (18%), Positives = 70/176 (39%), Gaps = 8/176 (4%)
Query: 5 FSVDDNNEEEEDVEMKEDSDENGPEEKQS--VEEMEEQSQDADGVNT-VTVPGPASEEAV 61
+S +++ E + +E E EE++S E E +S +++G + V
Sbjct: 1614 YSEEESEFSESETTEEESESETPSEEEESSTPESEESESTESEGEKARKNIVLARRRPMV 1673
Query: 62 EDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELS 121
E+ K+ K+E E + + +++H + +E+ E + E+Q E S
Sbjct: 1674 EEVKEVKGRKEE---PQEEQKEPKMEEEEHSEEEESGPAPVEESTDPEAQDIPEEGSAES 1730
Query: 122 SNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVE 177
++ E V E+ + E + G P +++ + +PG + E
Sbjct: 1731 ASVEGGVESEEESESGSSSSSSESQSGGPWGYQVPAYDRSK--NANQKKSPGANSE 1784
>gi|21735569 claspin [Homo sapiens]
Length = 1339
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 10/123 (8%)
Query: 12 EEEEDVEMKEDSDENGPE-------EKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDC 64
EEEE+ EM ++S+E+G E E++ EE E++ ++ + N T S E +E
Sbjct: 631 EEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLSSEEIETK 690
Query: 65 KDEDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQ 124
+++ K+ N G +V P +DST K ++ S+ Y TEE S
Sbjct: 691 DEKEMDKENN--DGSSEIGKAVGFLSVPKSLSSDSTLLLFK-DSSSKMGYFPTEEKSETD 747
Query: 125 EDA 127
E++
Sbjct: 748 ENS 750
Score = 29.3 bits (64), Expect = 2.6
Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 8/112 (7%)
Query: 102 NEIKIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDT------ 155
NE E E + T+E + E+ V E+ E E+++E+E E+ ++T
Sbjct: 624 NEDGFEEEEEEEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEEEEEGNQETAEFLLS 683
Query: 156 -PRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAK 206
+ K E D EN G E+ V ++ P + L+ +K
Sbjct: 684 SEEIETKDEKEMDKENNDGSS-EIGKAVGFLSVPKSLSSDSTLLLFKDSSSK 734
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 46.2 bits (108), Expect = 2e-05
Identities = 35/192 (18%), Positives = 66/192 (34%), Gaps = 3/192 (1%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
S N+ + D + SD N + S + S D+D ++ + D
Sbjct: 555 SDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSS 614
Query: 66 DEDFAKDENITKGGEVTDHSVRD--QDHPDGQENDSTKNEIKIETESQSSYMETEELSSN 123
D + D +D S D D D +DS+ N ++ + S+ ++ + SS+
Sbjct: 615 DSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD-SSD 673
Query: 124 QEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVD 183
D+ + D + + + S SSD N+ D + ++ D
Sbjct: 674 SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD 733
Query: 184 KVNDPTESQQED 195
+ S D
Sbjct: 734 SSDSSNSSDSSD 745
Score = 43.9 bits (102), Expect = 1e-04
Identities = 32/189 (16%), Positives = 74/189 (39%), Gaps = 9/189 (4%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDE 67
+D+N++ + + K DS ++ + + + + S + + +S+ D D
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Query: 68 DFAKDENITKGGEVTDHSVRDQDHPDGQE-NDSTKNEIKIETESQSSYMETEELSSNQED 126
D + N + + +D S D D + +DS + K E++S S +++ SN D
Sbjct: 594 DSSDSSNSSDSSDSSDSS----DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSD 649
Query: 127 AVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVN 186
+ + + D+ S+ S+ +++ D +S+ +
Sbjct: 650 S----SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSS 705
Query: 187 DPTESQQED 195
D ++S D
Sbjct: 706 DSSDSDSSD 714
Score = 37.4 bits (85), Expect = 0.010
Identities = 32/209 (15%), Positives = 72/209 (34%), Gaps = 13/209 (6%)
Query: 9 DNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDED 68
D++ + + + SD + + S +D N+ + D D D
Sbjct: 760 DSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSD 819
Query: 69 FAKDENITKGGEVTDHSVRDQ-----DHPDGQENDSTKNEIKIETESQSSYMETEELSSN 123
+ + + + +D S D DG ++DS+ + ++ + S ++ + S++
Sbjct: 820 SSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN---RSDSSNSSDSSDSSDSSNS 876
Query: 124 QEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVD 183
+ + + E ++ + + D+ S SSD N+ NS D
Sbjct: 877 SDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS----SNSSDSSDSSNSSDSSESSNSS-D 931
Query: 184 KVNDPTESQQEDQLIAGAQDEAKEQRNGT 212
N S D + + + N +
Sbjct: 932 NSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Score = 36.6 bits (83), Expect = 0.016
Identities = 33/144 (22%), Positives = 51/144 (35%), Gaps = 3/144 (2%)
Query: 71 KDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQEDAVIV 130
K+ENIT G S+ D + N + + + E+++ QED V
Sbjct: 127 KEENITANGIQGQVSIIDNAGATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQV 186
Query: 131 EQPEVIPLTEDQ---EEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVND 187
ED+ E E TP++ K G+ + E TPG + +
Sbjct: 187 AGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSP 246
Query: 188 PTESQQEDQLIAGAQDEAKEQRNG 211
ED+ DE +E NG
Sbjct: 247 SGNGADEDEDEGSGDDEDEEAGNG 270
Score = 34.7 bits (78), Expect = 0.062
Identities = 33/217 (15%), Positives = 68/217 (31%), Gaps = 28/217 (12%)
Query: 2 NEFFSVDDNN-----------------------EEEEDVEMKEDSDENGPEEKQSVEEME 38
N S D ++ + E + SD + + S +
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 39 EQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDENITKGGEVTDHSVRDQDHPDGQEND 98
S D+D N+ ++ D D + D + + + S D D ++
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 99 STKNEIKIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRM 158
++ + S SS SSN D+ + ++ + + D+
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDS-----SDSSDSSDSDSSNSSDSSNSSDSSDS 835
Query: 159 PGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQED 195
S+ S +++ G D + +++ D N S D
Sbjct: 836 SNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872
Score = 33.5 bits (75), Expect = 0.14
Identities = 41/215 (19%), Positives = 74/215 (34%), Gaps = 27/215 (12%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGV-------NTVTVPGPA-SEE 59
D + +E + SD G E+ S + + D++G N + G S+
Sbjct: 490 DASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDS 549
Query: 60 AVEDCKDEDFAKDENITKGGEVTD-HSVRDQDHPDGQENDSTKNEIKIETESQSSYMETE 118
+ D D + D + + + +D +S D D D +DS+ ++ S SS
Sbjct: 550 SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD-----SSDSSNSSDS 604
Query: 119 ELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEM 178
SS+ D + D + K+ + S+ SD ++ D
Sbjct: 605 SDSSDSSD------------SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD 652
Query: 179 NS-QVDKVNDPTESQQEDQLIAGAQDEAKEQRNGT 212
NS D N S D + + + N +
Sbjct: 653 NSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687
Score = 31.2 bits (69), Expect = 0.68
Identities = 31/188 (16%), Positives = 63/188 (33%), Gaps = 5/188 (2%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
S N+ + D DS E+ S + S +D ++ + D
Sbjct: 906 SDSSNSSDSSDSSNSSDSSESSNSSDNS--NSSDSSNSSDSSDSSDSSNSSDSSNSSDSS 963
Query: 66 DEDFAKDENITKGGEVTD--HSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSN 123
+ + D N + + ++ S D D ++ + N S SS SSN
Sbjct: 964 NSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSN 1023
Query: 124 QEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVD 183
D+ + D + + + D+ S+ S +++ D +S
Sbjct: 1024 SSDSSNSSDSSDSSDSSDSSD-SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1082
Query: 184 KVNDPTES 191
+ +D ++S
Sbjct: 1083 ESSDSSDS 1090
Score = 30.8 bits (68), Expect = 0.89
Identities = 26/188 (13%), Positives = 60/188 (31%), Gaps = 2/188 (1%)
Query: 6 SVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
S ++ D DS ++ + S +D ++ + D
Sbjct: 792 SDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS 851
Query: 66 DEDFAKDENITKGGEVTD--HSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSN 123
D D + + + + +D S D D +++ + N S SS ++ + S++
Sbjct: 852 DSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNS 911
Query: 124 QEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVD 183
+ + + + + + S SSD N+ +S
Sbjct: 912 SDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDS 971
Query: 184 KVNDPTES 191
+D ++S
Sbjct: 972 NSSDSSDS 979
>gi|13569879 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member E isoform 1 [Homo sapiens]
Length = 268
Score = 46.2 bits (108), Expect = 2e-05
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 10/127 (7%)
Query: 26 NGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDE----NITKGGEV 81
N + ++S+ E+ +Q DG + P SEE ++ DED ++E +G E
Sbjct: 127 NLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEE 186
Query: 82 TDHSVRDQDHPDGQENDSTKNEI-KIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTE 140
+ ++D + ++ D +E+ + E E SY+ EE+ ++D VE+ E E
Sbjct: 187 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE-----E 241
Query: 141 DQEEKEG 147
++EE+EG
Sbjct: 242 EEEEEEG 248
Score = 38.1 bits (87), Expect = 0.006
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 15/105 (14%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA------- 60
+D +E++E+ E E G EE++ EE E++ +D D + G EE
Sbjct: 164 EDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMK 223
Query: 61 --VEDCKDED-----FAKDENITKGGEVTDHSVRDQDHPDGQEND 98
++D +D+D ++E +GG + RD + DG+E D
Sbjct: 224 EEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE-DDGEEED 267
Score = 35.0 bits (79), Expect = 0.047
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEE------MEEQSQDADGVNTVTVPGPA 56
E + ++ EEEED + ED DE G E + EE M+E+ QD + + G
Sbjct: 182 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 241
Query: 57 SEEAVE 62
EE E
Sbjct: 242 EEEEEE 247
Score = 28.9 bits (63), Expect = 3.4
Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 141 DQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAG 200
DQE+ E + ED G + + EN GP + ++ + E + ED+ AG
Sbjct: 149 DQEDNEAPDSEEEDDE--DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAG 206
Query: 201 AQDEAKEQRNG 211
++ E+ G
Sbjct: 207 SELGEGEEEVG 217
Score = 27.3 bits (59), Expect = 9.9
Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 11/110 (10%)
Query: 107 ETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSS 166
+ ++++ E E+ ED E+ E P +EE+E E+ ED + E S
Sbjct: 150 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE--DEDEAGS 207
Query: 167 DL---ENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRNGTK 213
+L E G M ++ + + +D + ++E +E+ G +
Sbjct: 208 ELGEGEEEVGLSYLMKEEIQ------DEEDDDDYVEEGEEEEEEEEGGLR 251
>gi|210147569 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 2 [Homo sapiens]
Length = 227
Score = 46.2 bits (108), Expect = 2e-05
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 10/127 (7%)
Query: 26 NGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDE----NITKGGEV 81
N + ++S+ E+ +Q DG + P SEE ++ DED ++E +G E
Sbjct: 86 NLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEE 145
Query: 82 TDHSVRDQDHPDGQENDSTKNEI-KIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTE 140
+ ++D + ++ D +E+ + E E SY+ EE+ ++D VE+ E E
Sbjct: 146 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE-----E 200
Query: 141 DQEEKEG 147
++EE+EG
Sbjct: 201 EEEEEEG 207
Score = 38.1 bits (87), Expect = 0.006
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 15/105 (14%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA------- 60
+D +E++E+ E E G EE++ EE E++ +D D + G EE
Sbjct: 123 EDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMK 182
Query: 61 --VEDCKDED-----FAKDENITKGGEVTDHSVRDQDHPDGQEND 98
++D +D+D ++E +GG + RD + DG+E D
Sbjct: 183 EEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE-DDGEEED 226
Score = 35.0 bits (79), Expect = 0.047
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEE------MEEQSQDADGVNTVTVPGPA 56
E + ++ EEEED + ED DE G E + EE M+E+ QD + + G
Sbjct: 141 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 200
Query: 57 SEEAVE 62
EE E
Sbjct: 201 EEEEEE 206
Score = 28.9 bits (63), Expect = 3.4
Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 141 DQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAG 200
DQE+ E + ED G + + EN GP + ++ + E + ED+ AG
Sbjct: 108 DQEDNEAPDSEEEDDE--DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAG 165
Query: 201 AQDEAKEQRNG 211
++ E+ G
Sbjct: 166 SELGEGEEEVG 176
Score = 27.3 bits (59), Expect = 9.9
Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 11/110 (10%)
Query: 107 ETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSS 166
+ ++++ E E+ ED E+ E P +EE+E E+ ED + E S
Sbjct: 109 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE--DEDEAGS 166
Query: 167 DL---ENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRNGTK 213
+L E G M ++ + + +D + ++E +E+ G +
Sbjct: 167 ELGEGEEEVGLSYLMKEEIQ------DEEDDDDYVEEGEEEEEEEEGGLR 210
>gi|210147571 acidic (leucine-rich) nuclear phosphoprotein 32
family, member E isoform 3 [Homo sapiens]
Length = 220
Score = 46.2 bits (108), Expect = 2e-05
Identities = 34/127 (26%), Positives = 63/127 (49%), Gaps = 10/127 (7%)
Query: 26 NGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKDEDFAKDE----NITKGGEV 81
N + ++S+ E+ +Q DG + P SEE ++ DED ++E +G E
Sbjct: 79 NLEDYRESIFELLQQITYLDGFDQEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEE 138
Query: 82 TDHSVRDQDHPDGQENDSTKNEI-KIETESQSSYMETEELSSNQEDAVIVEQPEVIPLTE 140
+ ++D + ++ D +E+ + E E SY+ EE+ ++D VE+ E E
Sbjct: 139 EEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGE-----E 193
Query: 141 DQEEKEG 147
++EE+EG
Sbjct: 194 EEEEEEG 200
Score = 38.1 bits (87), Expect = 0.006
Identities = 28/105 (26%), Positives = 49/105 (46%), Gaps = 15/105 (14%)
Query: 8 DDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEA------- 60
+D +E++E+ E E G EE++ EE E++ +D D + G EE
Sbjct: 116 EDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMK 175
Query: 61 --VEDCKDED-----FAKDENITKGGEVTDHSVRDQDHPDGQEND 98
++D +D+D ++E +GG + RD + DG+E D
Sbjct: 176 EEIQDEEDDDDYVEEGEEEEEEEEGGLRGEKRKRDAE-DDGEEED 219
Score = 35.0 bits (79), Expect = 0.047
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 3 EFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEE------MEEQSQDADGVNTVTVPGPA 56
E + ++ EEEED + ED DE G E + EE M+E+ QD + + G
Sbjct: 134 EGYEEEEEEEEEEDEDEDEDEDEAGSELGEGEEEVGLSYLMKEEIQDEEDDDDYVEEGEE 193
Query: 57 SEEAVE 62
EE E
Sbjct: 194 EEEEEE 199
Score = 28.9 bits (63), Expect = 3.4
Identities = 18/71 (25%), Positives = 31/71 (43%), Gaps = 2/71 (2%)
Query: 141 DQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAG 200
DQE+ E + ED G + + EN GP + ++ + E + ED+ AG
Sbjct: 101 DQEDNEAPDSEEEDDE--DGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDEDEDEAG 158
Query: 201 AQDEAKEQRNG 211
++ E+ G
Sbjct: 159 SELGEGEEEVG 169
Score = 27.3 bits (59), Expect = 9.9
Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 11/110 (10%)
Query: 107 ETESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSS 166
+ ++++ E E+ ED E+ E P +EE+E E+ ED + E S
Sbjct: 102 QEDNEAPDSEEEDDEDGDEDDEEEEENEAGPPEGYEEEEEEEEEEDEDEDE--DEDEAGS 159
Query: 167 DL---ENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQRNGTK 213
+L E G M ++ + + +D + ++E +E+ G +
Sbjct: 160 ELGEGEEEVGLSYLMKEEIQ------DEEDDDDYVEEGEEEEEEEEGGLR 203
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/204 (22%), Positives = 91/204 (44%), Gaps = 26/204 (12%)
Query: 7 VDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKD 66
+ ++ EE +D K+DS ++ P K + +E+S+ D + T P + EE+ E
Sbjct: 1468 IKESQEERKDT-FKKDSQQDIPSSK----DHKEKSEFVDDITTRREPYDSVEESSESENS 1522
Query: 67 EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQED 126
+ + G +D ++ G+E D + +I IE + E+ S +++D
Sbjct: 1523 PVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI-IEMSAD------EDASGSEDD 1575
Query: 127 AVIVEQPEVIPLTEDQEEKEGEKAPGEDTP----RMPGKSEGSSDLENTPGPDVEMNSQV 182
I Q + I + + ++KE K G+ T R+ KS S+ ++ G + +
Sbjct: 1576 EFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKS--STSIDEDAGRRHSWHDED 1633
Query: 183 DKVND--------PTESQQEDQLI 198
D+ D T+SQ+ ++L+
Sbjct: 1634 DEAFDESPELKYRETKSQESEELV 1657
Score = 38.9 bits (89), Expect = 0.003
Identities = 55/223 (24%), Positives = 83/223 (37%), Gaps = 43/223 (19%)
Query: 13 EEED------VEMKEDSDENGPEEKQSVE-EMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
EEED +EM D D +G E+ + + +++E S + G A
Sbjct: 1551 EEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITA----- 1605
Query: 66 DEDFAKDENITKGGEVT---DHSVRDQDHPDGQENDSTKNEIKI-ETESQSSY------- 114
K +T+ + D R H + E E+K ET+SQ S
Sbjct: 1606 ----GKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGG 1661
Query: 115 -----METEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLE 169
+T EL+S D E + EE E E D+P + EGSS L
Sbjct: 1662 GGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLH 1721
Query: 170 N---TPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQR 209
TPG S +D+ +D + S + + E+K+QR
Sbjct: 1722 ASSFTPGTSPTSVSSLDEDSDSSPSHK--------KGESKQQR 1756
Score = 38.1 bits (87), Expect = 0.006
Identities = 46/221 (20%), Positives = 93/221 (42%), Gaps = 32/221 (14%)
Query: 14 EEDVEMKED-SDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPA-----SEEAVEDCKDE 67
+E E ++D SD + ++ +S + + + +DG+++ P+ ++ ++ K +
Sbjct: 1336 KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD 1395
Query: 68 DFAKDEN----------------------ITKGGEVTDHSVRDQDHPDGQENDSTKNEIK 105
F+++ + T E ++ + + Q D K +
Sbjct: 1396 SFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSL 1455
Query: 106 IET-ESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKS-E 163
ET E S E +E ++D + + IP ++D +EK E T R P S E
Sbjct: 1456 SETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS-EFVDDITTRREPYDSVE 1514
Query: 164 GSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDE 204
SS+ EN+P P + + V + E +QED +G +++
Sbjct: 1515 ESSESENSPVPQRKRRTSVGS-SSSDEYKQEDSQGSGEEED 1554
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 45.8 bits (107), Expect = 3e-05
Identities = 46/204 (22%), Positives = 91/204 (44%), Gaps = 26/204 (12%)
Query: 7 VDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCKD 66
+ ++ EE +D K+DS ++ P K + +E+S+ D + T P + EE+ E
Sbjct: 1468 IKESQEERKDT-FKKDSQQDIPSSK----DHKEKSEFVDDITTRREPYDSVEESSESENS 1522
Query: 67 EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQED 126
+ + G +D ++ G+E D + +I IE + E+ S +++D
Sbjct: 1523 PVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQI-IEMSAD------EDASGSEDD 1575
Query: 127 AVIVEQPEVIPLTEDQEEKEGEKAPGEDTP----RMPGKSEGSSDLENTPGPDVEMNSQV 182
I Q + I + + ++KE K G+ T R+ KS S+ ++ G + +
Sbjct: 1576 EFIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKS--STSIDEDAGRRHSWHDED 1633
Query: 183 DKVND--------PTESQQEDQLI 198
D+ D T+SQ+ ++L+
Sbjct: 1634 DEAFDESPELKYRETKSQESEELV 1657
Score = 38.9 bits (89), Expect = 0.003
Identities = 55/223 (24%), Positives = 83/223 (37%), Gaps = 43/223 (19%)
Query: 13 EEED------VEMKEDSDENGPEEKQSVE-EMEEQSQDADGVNTVTVPGPASEEAVEDCK 65
EEED +EM D D +G E+ + + +++E S + G A
Sbjct: 1551 EEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKGKGKITA----- 1605
Query: 66 DEDFAKDENITKGGEVT---DHSVRDQDHPDGQENDSTKNEIKI-ETESQSSY------- 114
K +T+ + D R H + E E+K ET+SQ S
Sbjct: 1606 ----GKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQESEELVVTGG 1661
Query: 115 -----METEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLE 169
+T EL+S D E + EE E E D+P + EGSS L
Sbjct: 1662 GGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSRGEGSSSLH 1721
Query: 170 N---TPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDEAKEQR 209
TPG S +D+ +D + S + + E+K+QR
Sbjct: 1722 ASSFTPGTSPTSVSSLDEDSDSSPSHK--------KGESKQQR 1756
Score = 38.1 bits (87), Expect = 0.006
Identities = 46/221 (20%), Positives = 93/221 (42%), Gaps = 32/221 (14%)
Query: 14 EEDVEMKED-SDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPA-----SEEAVEDCKDE 67
+E E ++D SD + ++ +S + + + +DG+++ P+ ++ ++ K +
Sbjct: 1336 KEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD 1395
Query: 68 DFAKDEN----------------------ITKGGEVTDHSVRDQDHPDGQENDSTKNEIK 105
F+++ + T E ++ + + Q D K +
Sbjct: 1396 SFSQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSL 1455
Query: 106 IET-ESQSSYMETEELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKS-E 163
ET E S E +E ++D + + IP ++D +EK E T R P S E
Sbjct: 1456 SETLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKS-EFVDDITTRREPYDSVE 1514
Query: 164 GSSDLENTPGPDVEMNSQVDKVNDPTESQQEDQLIAGAQDE 204
SS+ EN+P P + + V + E +QED +G +++
Sbjct: 1515 ESSESENSPVPQRKRRTSVGS-SSSDEYKQEDSQGSGEEED 1554
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 45.4 bits (106), Expect = 4e-05
Identities = 49/214 (22%), Positives = 90/214 (42%), Gaps = 39/214 (18%)
Query: 2 NEFFSVDDNNEEEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAV 61
++FF + + E++E +E+ ++ EE++ ++ E+ D D S ++
Sbjct: 202 DKFFKLSEMEAYLENIEKEEERKDDNDEEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSS 261
Query: 62 EDCKDEDF----AKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMET 117
+ K +DF DE+IT +V D + +E+D E E
Sbjct: 262 RNLKYKDFFDPVESDEDIT--------NVHDDELDSNKEDDEIAEE------------EA 301
Query: 118 EELSSNQEDAVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVE 177
EELS ++ D +D +E E K E R+ ++ E+T +V+
Sbjct: 302 EELSISETDE-----------DDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVK 350
Query: 178 MNSQVDKVNDPTESQQE--DQLIAGAQDEAKEQR 209
NS D+V E +QE ++ IA + E E++
Sbjct: 351 KNS--DEVKSSFEKRQEKMNEKIASLEKELLEKK 382
Score = 43.5 bits (101), Expect = 1e-04
Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 14/202 (6%)
Query: 13 EEEDVEMKEDSDENGPEEKQSVEEMEEQSQDADGVNTVTVPGPASEEAVEDCK------D 66
E E+ E +ED E ++K+ +E++EE+ G + + A + D + D
Sbjct: 109 ESEEQEREEDGSEIEADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSD 168
Query: 67 EDFAKDENITKGGEVTDHSVRDQDHPDGQENDSTKNEIKIETESQSSYMETEELSSNQED 126
ED D +I+K + + + Q P + K E E+ +E EE + D
Sbjct: 169 EDSDLDFDISKLEQQSKVQNKGQGKPREKSIVDDKFFKLSEMEAYLENIEKEEERKDDND 228
Query: 127 AVIVEQPEVIPLTEDQEEKEGEKAPGEDTPRMPGKSEGSSDLENTPGPDVEMNSQVDKV- 185
E+ E I ED + E E GKS + ++ P VE + + V
Sbjct: 229 ----EEEEDIDFFEDIDSDEDEGGLFGSKKLKSGKSSRNLKYKDFFDP-VESDEDITNVH 283
Query: 186 NDPTESQQEDQLIAGAQDEAKE 207
+D +S +ED I A++EA+E
Sbjct: 284 DDELDSNKEDDEI--AEEEAEE 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.295 0.120 0.313
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,893,187
Number of Sequences: 37866
Number of extensions: 528836
Number of successful extensions: 6896
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 310
Number of HSP's successfully gapped in prelim test: 470
Number of HSP's that attempted gapping in prelim test: 2978
Number of HSP's gapped (non-prelim): 2534
length of query: 213
length of database: 18,247,518
effective HSP length: 98
effective length of query: 115
effective length of database: 14,536,650
effective search space: 1671714750
effective search space used: 1671714750
T: 11
A: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 44 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.