Search of human proteins with 74027265

Search of human proteins with 74027265

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
precursor [Homo sapiens]
         (513 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2 ...  1095   0.0  
gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2 p...  1095   0.0  
gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1 ...  1084   0.0  
gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo sapi...   123   5e-28
gi|239787919 low density lipoprotein receptor-related protein 11...   110   2e-24
gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]           100   4e-21
gi|5454114 tissue factor pathway inhibitor isoform a precursor [...    98   2e-20
gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo sap...    72   1e-12
gi|4502167 amyloid beta A4 protein isoform a precursor [Homo sap...    66   7e-11
gi|209915573 amyloid beta A4 protein isoform f precursor [Homo s...    66   7e-11
gi|41406055 amyloid beta A4 protein isoform b precursor [Homo sa...    63   6e-10
gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform ...    62   1e-09
gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1 ...    62   1e-09
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...    61   3e-09
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...    61   3e-09
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...    61   3e-09
gi|73760409 tissue factor pathway inhibitor isoform b precursor ...    60   6e-09
gi|145309328 papilin [Homo sapiens]                                    60   6e-09
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n...    59   1e-08
gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP...    58   2e-08
gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP...    58   2e-08
gi|28212222 WFIKKN2 protein [Homo sapiens]                             58   2e-08
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]            54   3e-07
gi|93102379 low density lipoprotein-related protein 1B precursor...    54   3e-07
gi|4507157 sortilin-related receptor containing LDLR class A rep...    52   1e-06
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa...    52   2e-06
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa...    52   2e-06
gi|61744471 low density lipoprotein receptor-related protein 8 i...    50   6e-06
gi|61744467 low density lipoprotein receptor-related protein 8 i...    50   6e-06
gi|66082554 low density lipoprotein receptor-related protein 8 i...    50   6e-06

>gi|74027265 serine peptidase inhibitor, Kunitz type 1 isoform 2
           precursor [Homo sapiens]
          Length = 513

 Score = 1095 bits (2831), Expect = 0.0
 Identities = 513/513 (100%), Positives = 513/513 (100%)

Query: 1   MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
           MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
Sbjct: 1   MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60

Query: 61  FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
           FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
Sbjct: 61  FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120

Query: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
           CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
Sbjct: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180

Query: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
           LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
Sbjct: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240

Query: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
           LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
Sbjct: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300

Query: 301 RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF 360
           RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF
Sbjct: 301 RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF 360

Query: 361 DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ 420
           DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ
Sbjct: 361 DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ 420

Query: 421 CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH 480
           CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH
Sbjct: 421 CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH 480

Query: 481 GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 513
           GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
Sbjct: 481 GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 513


>gi|4504329 serine peptidase inhibitor, Kunitz type 1 isoform 2
           precursor [Homo sapiens]
          Length = 513

 Score = 1095 bits (2831), Expect = 0.0
 Identities = 513/513 (100%), Positives = 513/513 (100%)

Query: 1   MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
           MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
Sbjct: 1   MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60

Query: 61  FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
           FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
Sbjct: 61  FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120

Query: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
           CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
Sbjct: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180

Query: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
           LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
Sbjct: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240

Query: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
           LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
Sbjct: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300

Query: 301 RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF 360
           RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF
Sbjct: 301 RGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGF 360

Query: 361 DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ 420
           DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ
Sbjct: 361 DELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQ 420

Query: 421 CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH 480
           CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH
Sbjct: 421 CLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGYCFFKNQRKDFH 480

Query: 481 GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 513
           GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
Sbjct: 481 GHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 513


>gi|32313599 serine peptidase inhibitor, Kunitz type 1 isoform 1
           precursor [Homo sapiens]
          Length = 529

 Score = 1084 bits (2804), Expect = 0.0
 Identities = 513/529 (96%), Positives = 513/529 (96%), Gaps = 16/529 (3%)

Query: 1   MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60
           MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG
Sbjct: 1   MAPARTMARARLAPAGIPAVALWLLCTLGLQGTQAGPPPAPPGLPAGADCLNSFTAGVPG 60

Query: 61  FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120
           FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN
Sbjct: 61  FVLDTNASVSNGATFLESPTVRRGWDCVRACCTTQNCNLALVELQPDRGEDAIAACFLIN 120

Query: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180
           CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV
Sbjct: 121 CLYEQNFVCKFAPREGFINYLTREVYRSYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLV 180

Query: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240
           LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV
Sbjct: 181 LKDVENTDWRLLRGDTDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTV 240

Query: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
           LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC
Sbjct: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300

Query: 301 RGV----------------QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 344
           RGV                QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC
Sbjct: 301 RGVQGGPLRGSSGAQATFPQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNC 360

Query: 345 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 404
           PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT
Sbjct: 361 PDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFT 420

Query: 405 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 464
           YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV
Sbjct: 421 YGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVV 480

Query: 465 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 513
           AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL
Sbjct: 481 AILGYCFFKNQRKDFHGHHHHPPPTPASSTVSTTEDTEHLVYNHTTRPL 529


>gi|10863909 serine protease inhibitor, Kunitz type, 2 [Homo
           sapiens]
          Length = 252

 Score =  123 bits (308), Expect = 5e-28
 Identities = 71/226 (31%), Positives = 102/226 (45%), Gaps = 38/226 (16%)

Query: 244 KQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGV 303
           +   D+CL S  VGRCR S PRW+Y+ T+  C+ FVYGGC GN NNYL +EEC+  C  V
Sbjct: 32  RSIHDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATV 91

Query: 304 QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDEL 363
                         T   T    ++    DS       P+ P   D          ++E 
Sbjct: 92  --------------TENATGDLATSRNAADS-----SVPSAPRRQDSEDHSSDMFNYEE- 131

Query: 364 QRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLE 423
                     +C     TG C+ S PRWY++     C  F YGGC GNKN++  E+ C+ 
Sbjct: 132 ----------YCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACML 181

Query: 424 SCRGISKKDVFGLRREIPIPSTGSVEMAVAVFLVICIVVVVAILGY 469
            C        F  +   P+P    V +   +F+++ I+ + A + Y
Sbjct: 182 RC--------FRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVY 219



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 35/75 (46%), Positives = 42/75 (56%), Gaps = 10/75 (13%)

Query: 226 SSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLG 285
           S DH  D  N           E+YC A+   G CR SFPRWY+D     C +F+YGGC G
Sbjct: 119 SEDHSSDMFNY----------EEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRG 168

Query: 286 NKNNYLREEECILAC 300
           NKN+Y  EE C+L C
Sbjct: 169 NKNSYRSEEACMLRC 183


>gi|239787919 low density lipoprotein receptor-related protein 11
           [Homo sapiens]
          Length = 500

 Score =  110 bits (276), Expect = 2e-24
 Identities = 98/335 (29%), Positives = 136/335 (40%), Gaps = 89/335 (26%)

Query: 36  GPPPAPPGLPAGADCLNSFTAGVPGFVLDTNASVSNGATFLESPTVRRGW-DCVRACCTT 94
           GP    PG  +G        + +P  ++ T  S++ GA+FL +P   RGW  CV ACC+ 
Sbjct: 84  GPQEDCPGPGSGG------YSAMPDAIIRTKDSLAAGASFLRAPAAVRGWRQCVAACCSE 137

Query: 95  QNCNLALVELQPDRGED--AIAACFLINCLYEQNFVCKFAPREGFINY-LTRE----VYR 147
             C++A+VEL P R     A+  C+L NC      VCKFA   G+ +Y L+R        
Sbjct: 138 PRCSVAVVEL-PRRPAPPAAVLGCYLFNCTARGRNVCKFALHSGYSSYSLSRAPDGAALA 196

Query: 148 SYRQLRTQGFGGSGIPKAWAGIDLKVQPQEPLVLKDVENTD--------WRLLRGDTDVR 199
           + R    Q      + KA   + L + P + +VL   E+TD        W LL+GD  V 
Sbjct: 197 TARASPRQEKDAPPLSKAGQDVVLHL-PTDGVVLDGRESTDDHAIVQYEWALLQGDPSVD 255

Query: 200 VERKDPNQVELWGLKEGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRC 259
           ++      ++L  L+EGTY FQLTVT +     + NV+VTVL                  
Sbjct: 256 MKVPQSGTLKLSHLQEGTYTFQLTVTDTAGQRSSDNVSVTVLRA---------------- 299

Query: 260 RGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTC 319
                            ++  GGCL   + Y                     H  C   C
Sbjct: 300 -----------------AYSTGGCLHTCSRY---------------------HFFCDDGC 321

Query: 320 QPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACE 354
                      CID  L CD    CPD SDE  C+
Sbjct: 322 -----------CIDITLACDGVQQCPDGSDEDFCQ 345


>gi|5730091 tissue factor pathway inhibitor 2 [Homo sapiens]
          Length = 235

 Score =  100 bits (248), Expect = 4e-21
 Identities = 67/195 (34%), Positives = 85/195 (43%), Gaps = 15/195 (7%)

Query: 243 TKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRG 302
           T    + CL     G CR    R+YYD   Q C+ F+YGGC GN NN+   E C  AC  
Sbjct: 29  TGNNAEICLLPLDYGPCRALLLRYYYDRYTQSCRQFLYGGCEGNANNFYTWEACDDACWR 88

Query: 303 VQGPSMERRHPV-----CSGTCQPTQFRCSNGCCIDSFLE-CDDTPNCPDASDEAACEKY 356
           ++      R  V     C G+ +   F  S+  C   F   C          DEA C   
Sbjct: 89  IEKVPKVCRLQVSVDDQCEGSTEKYFFNLSSMTCEKFFSGGCHRNRIENRFPDEATC--- 145

Query: 357 TSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFE 416
             GF   ++I  PS    C    D GLC  ++ R+Y+NP    C  FTY GC GN NNF 
Sbjct: 146 -MGFCAPKKI--PS---FCYSPKDEGLCSANVTRYYFNPRYRTCDAFTYTGCGGNDNNFV 199

Query: 417 EEQQCLESCRGISKK 431
             + C  +C    KK
Sbjct: 200 SREDCKRACAKALKK 214


>gi|5454114 tissue factor pathway inhibitor isoform a precursor
           [Homo sapiens]
          Length = 304

 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 62/195 (31%), Positives = 86/195 (44%), Gaps = 33/195 (16%)

Query: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
           D AN  +     ++  D+C      G CRG   R++Y+   + C+ F YGGCLGN NN+ 
Sbjct: 107 DNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFE 166

Query: 292 REEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 351
             EEC   C    GP                     NG  +D++       N  + S   
Sbjct: 167 TLEECKNICE--DGP---------------------NGFQVDNY---GTQLNAVNNSLTP 200

Query: 352 ACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGN 411
              K  S F+     H PS    C+   D GLC+ +  R+YYN     C  F Y GC GN
Sbjct: 201 QSTKVPSLFE----FHGPS---WCLTPADRGLCRANENRFYYNSVIGKCRPFKYSGCGGN 253

Query: 412 KNNFEEEQQCLESCR 426
           +NNF  +Q+CL +C+
Sbjct: 254 ENNFTSKQECLRACK 268



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 21/51 (41%), Positives = 30/51 (58%)

Query: 375 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
           C    D G CK  + R+++N F+  C  F YGGC GN+N FE  ++C + C
Sbjct: 54  CAFKADDGPCKAIMKRFFFNIFTRQCEEFIYGGCEGNQNRFESLEECKKMC 104


>gi|4502067 alpha-1-microglobulin/bikunin preproprotein [Homo
           sapiens]
          Length = 352

 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 48/186 (25%), Positives = 67/186 (36%), Gaps = 69/186 (37%)

Query: 240 VLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILA 299
           V    + ED C      G C G   R++Y+ T   C++F YGGC+GN NN++ E+EC+  
Sbjct: 221 VTEVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQT 280

Query: 300 CRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSG 359
           CR V   ++    P+  G C+                                       
Sbjct: 281 CRTVAACNL----PIVRGPCRAF------------------------------------- 299

Query: 360 FDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQ 419
              +Q   F + KG CV  P                         YGGC GN N F  E+
Sbjct: 300 ---IQLWAFDAVKGKCVLFP-------------------------YGGCQGNGNKFYSEK 331

Query: 420 QCLESC 425
           +C E C
Sbjct: 332 ECREYC 337



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 22/48 (45%), Positives = 30/48 (62%)

Query: 382 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGIS 429
           G C     R++YN  S  C  F YGGC GN NNF  E++CL++CR ++
Sbjct: 238 GPCMGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVA 285



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 26/69 (37%), Positives = 31/69 (44%), Gaps = 1/69 (1%)

Query: 241 LSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
           L T +T   C      G CR     W +D  +  C  F YGGC GN N +  E+EC   C
Sbjct: 278 LQTCRTVAACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYC 337

Query: 301 RGVQGPSME 309
            GV G   E
Sbjct: 338 -GVPGDGDE 345


>gi|4502167 amyloid beta A4 protein isoform a precursor [Homo
           sapiens]
          Length = 770

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 6/117 (5%)

Query: 233 TANVTVTVLSTKQTEDY----CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKN 288
           T+  T T  +T+  E+     C    + G CR    RWY+D TE  C  F YGGC GN+N
Sbjct: 270 TSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRN 329

Query: 289 NYLREEECILACRGVQGPSMER--RHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPN 343
           N+  EE C+  C      S+ +  + P+     +      S    +D +LE     N
Sbjct: 330 NFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDEN 386



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 6/79 (7%)

Query: 375 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVF 434
           C +  +TG C+  I RWY++     CA F YGGC GN+NNF+ E+ C+  C     + + 
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLL 350

Query: 435 GLRRE------IPIPSTGS 447
              +E      + +P+T +
Sbjct: 351 KTTQEPLARDPVKLPTTAA 369


>gi|209915573 amyloid beta A4 protein isoform f precursor [Homo
           sapiens]
          Length = 714

 Score = 66.2 bits (160), Expect = 7e-11
 Identities = 36/117 (30%), Positives = 52/117 (44%), Gaps = 6/117 (5%)

Query: 233 TANVTVTVLSTKQTEDY----CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKN 288
           T+  T T  +T+  E+     C    + G CR    RWY+D TE  C  F YGGC GN+N
Sbjct: 214 TSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRN 273

Query: 289 NYLREEECILACRGVQGPSMER--RHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPN 343
           N+  EE C+  C      S+ +  + P+     +      S    +D +LE     N
Sbjct: 274 NFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDEN 330



 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 26/79 (32%), Positives = 42/79 (53%), Gaps = 6/79 (7%)

Query: 375 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVF 434
           C +  +TG C+  I RWY++     CA F YGGC GN+NNF+ E+ C+  C     + + 
Sbjct: 235 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLL 294

Query: 435 GLRRE------IPIPSTGS 447
              +E      + +P+T +
Sbjct: 295 KTTQEPLARDPVKLPTTAA 313


>gi|41406055 amyloid beta A4 protein isoform b precursor [Homo
           sapiens]
          Length = 751

 Score = 63.2 bits (152), Expect = 6e-10
 Identities = 29/72 (40%), Positives = 38/72 (52%), Gaps = 4/72 (5%)

Query: 233 TANVTVTVLSTKQTEDY----CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKN 288
           T+  T T  +T+  E+     C    + G CR    RWY+D TE  C  F YGGC GN+N
Sbjct: 270 TSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRN 329

Query: 289 NYLREEECILAC 300
           N+  EE C+  C
Sbjct: 330 NFDTEEYCMAVC 341



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 23/51 (45%), Positives = 32/51 (62%)

Query: 375 CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
           C +  +TG C+  I RWY++     CA F YGGC GN+NNF+ E+ C+  C
Sbjct: 291 CSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVC 341


>gi|214010181 amyloid beta (A4) precursor-like protein 2 isoform 2
           [Homo sapiens]
          Length = 751

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 25/57 (43%), Positives = 33/57 (57%)

Query: 372 KGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 428
           K  C     TG C+  +PRWY++     C RF YGGC GN+NNFE E  C+  C+ +
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 6/118 (5%)

Query: 196 TDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPED--TANVTVTVLSTKQ-TEDY--- 249
           T+  V+  D ++ E   + E    +  T    D+ E+  T   +   +S K+ T D    
Sbjct: 250 TEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309

Query: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307
           C      G CR   PRWY+D ++  C  F+YGGC GN+NN+  E+ C+  C+ +  P+
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPT 367


>gi|4502147 amyloid beta (A4) precursor-like protein 2 isoform 1
           [Homo sapiens]
          Length = 763

 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 25/57 (43%), Positives = 33/57 (57%)

Query: 372 KGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGI 428
           K  C     TG C+  +PRWY++     C RF YGGC GN+NNFE E  C+  C+ +
Sbjct: 307 KAVCSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAM 363



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 36/118 (30%), Positives = 58/118 (49%), Gaps = 6/118 (5%)

Query: 196 TDVRVERKDPNQVELWGLKEGTYLFQLTVTSSDHPED--TANVTVTVLSTKQ-TEDY--- 249
           T+  V+  D ++ E   + E    +  T    D+ E+  T   +   +S K+ T D    
Sbjct: 250 TEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAV 309

Query: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPS 307
           C      G CR   PRWY+D ++  C  F+YGGC GN+NN+  E+ C+  C+ +  P+
Sbjct: 310 CSQEAMTGPCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPT 367


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 23/52 (44%), Positives = 35/52 (67%)

Query: 380  DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKK 431
            D G C++ I +WYY+P ++ CARF YGGC GN+N F  +++C + C  +  K
Sbjct: 2911 DEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2962



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 1/72 (1%)

Query: 233  TANVTVTVLSTKQTE-DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
            T N+ V+      TE D C      G CR    +WYYDP  + C  F YGGC GN+N + 
Sbjct: 2888 TINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFG 2947

Query: 292  REEECILACRGV 303
             ++EC   C  V
Sbjct: 2948 SQKECEKVCAPV 2959


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 23/52 (44%), Positives = 35/52 (67%)

Query: 380  DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKK 431
            D G C++ I +WYY+P ++ CARF YGGC GN+N F  +++C + C  +  K
Sbjct: 3117 DEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 3168



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 1/72 (1%)

Query: 233  TANVTVTVLSTKQTE-DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
            T N+ V+      TE D C      G CR    +WYYDP  + C  F YGGC GN+N + 
Sbjct: 3094 TINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFG 3153

Query: 292  REEECILACRGV 303
             ++EC   C  V
Sbjct: 3154 SQKECEKVCAPV 3165


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 23/52 (44%), Positives = 35/52 (67%)

Query: 380  DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKK 431
            D G C++ I +WYY+P ++ CARF YGGC GN+N F  +++C + C  +  K
Sbjct: 2510 DEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAK 2561



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 28/72 (38%), Positives = 36/72 (50%), Gaps = 1/72 (1%)

Query: 233  TANVTVTVLSTKQTE-DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
            T N+ V+      TE D C      G CR    +WYYDP  + C  F YGGC GN+N + 
Sbjct: 2487 TINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFG 2546

Query: 292  REEECILACRGV 303
             ++EC   C  V
Sbjct: 2547 SQKECEKVCAPV 2558


>gi|73760409 tissue factor pathway inhibitor isoform b precursor
           [Homo sapiens]
          Length = 251

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 2/76 (2%)

Query: 232 DTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYL 291
           D AN  +     ++  D+C      G CRG   R++Y+   + C+ F YGGCLGN NN+ 
Sbjct: 107 DNANRIIKTTLQQEKPDFCFLEEDPGICRGYITRYFYNNQTKQCERFKYGGCLGNMNNFE 166

Query: 292 REEECILACRGVQGPS 307
             EEC   C    GP+
Sbjct: 167 TLEECKNICE--DGPN 180



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 47/206 (22%), Positives = 70/206 (33%), Gaps = 58/206 (28%)

Query: 222 LTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYG 281
           L   S +  E T      +   K    +C      G C+    R++++   + C+ F+YG
Sbjct: 26  LNADSEEDEEHTIITDTELPPLKLMHSFCAFKADDGPCKAIMKRFFFNIFTRQCEEFIYG 85

Query: 282 GCLGNKNNYLREEECILACRGVQG--PSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECD 339
           G                 C G Q    S+E                C   C  D+     
Sbjct: 86  G-----------------CEGNQNRFESLEE---------------CKKMCTRDNANRII 113

Query: 340 DTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEH 399
            T    +  D    E+                        D G+C+  I R++YN  ++ 
Sbjct: 114 KTTLQQEKPDFCFLEE------------------------DPGICRGYITRYFYNNQTKQ 149

Query: 400 CARFTYGGCYGNKNNFEEEQQCLESC 425
           C RF YGGC GN NNFE  ++C   C
Sbjct: 150 CERFKYGGCLGNMNNFETLEECKNIC 175


>gi|145309328 papilin [Homo sapiens]
          Length = 1251

 Score = 59.7 bits (143), Expect = 6e-09
 Identities = 27/60 (45%), Positives = 34/60 (56%), Gaps = 4/60 (6%)

Query: 382 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISKKDVFGLRREIP 441
           G C +   RWY+      C RF YGGC+GN NNF  EQ+C+ SC+G     + G RR  P
Sbjct: 734 GSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQG----SLHGPRRPQP 789



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 3/69 (4%)

Query: 250 CLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRG-VQGPSM 308
           CL  +  G C     RWY+  +   C  F YGGC GN NN+  E+EC+ +C+G + GP  
Sbjct: 727 CLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQGSLHGP-- 784

Query: 309 ERRHPVCSG 317
            R  P  SG
Sbjct: 785 RRPQPGASG 793


>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
           netrin domain containing 1 precursor [Homo sapiens]
          Length = 548

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 27/53 (50%), Positives = 29/53 (54%)

Query: 248 DYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC 300
           D C+     G CRG  PRW Y P  Q C  FVYGGC GN NN+   E C  AC
Sbjct: 357 DACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGNGNNFHSRESCEDAC 409



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 3/76 (3%)

Query: 353 CEKYTSGFDELQRIHFPSDKGH---CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCY 409
           C+    GF+  +       +G    CV     G C+   PRW Y+P  + C  F YGGC 
Sbjct: 334 CDGAARGFETYEACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCE 393

Query: 410 GNKNNFEEEQQCLESC 425
           GN NNF   + C ++C
Sbjct: 394 GNGNNFHSRESCEDAC 409



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 31/110 (28%), Positives = 39/110 (35%), Gaps = 28/110 (25%)

Query: 266 WYYDPTEQICKSFVYGGCLGNKNNYLREEECILAC-RG---------VQGPS-------- 307
           W+YDP    C +F   GC G    +   E C  AC RG         VQGP         
Sbjct: 317 WHYDPQRGGCMTFPARGCDGAARGFETYEACQQACARGPGDACVLPAVQGPCRGWEPRWA 376

Query: 308 ----MERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 353
               +++ HP   G C+       NG    S   C+D    P      AC
Sbjct: 377 YSPLLQQCHPFVYGGCE------GNGNNFHSRESCEDACPVPRTPPCRAC 420



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 4/52 (7%)

Query: 378 LPD----TGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
           LPD    TG     +  W+Y+P    C  F   GC G    FE  + C ++C
Sbjct: 300 LPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCDGAARGFETYEACQQAC 351


>gi|31563528 serine peptidase inhibitor-like, with Kunitz and WAP
           domains 1 isoform 2 [Homo sapiens]
          Length = 117

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGP 306
           +D C    + G C   F  W+YD  +  C  FVYGGC GN NN+  +  C+  C+  + P
Sbjct: 58  QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 117



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 19/47 (40%), Positives = 27/47 (57%)

Query: 380 DTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCR 426
           +TG C      W+Y+     C+ F YGGC GN NNF+ +  CL +C+
Sbjct: 66  ETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCK 112


>gi|10732863 serine peptidase inhibitor-like, with Kunitz and WAP
           domains 1 isoform 1 precursor [Homo sapiens]
          Length = 133

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 22/60 (36%), Positives = 31/60 (51%)

Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGP 306
           +D C    + G C   F  W+YD  +  C  FVYGGC GN NN+  +  C+  C+  + P
Sbjct: 74  QDVCEMPKETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQSKANCLNTCKNKRFP 133



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 36/129 (27%), Positives = 51/129 (39%), Gaps = 24/129 (18%)

Query: 303 VQGPSME-----RRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYT 357
           VQGP +      RR P     C+   F+  + C  D   +C D   C   S    C    
Sbjct: 19  VQGPGLTDWLFPRRCPKIREECE---FQERDVCTKDR--QCQDNKKCCVFSCGKKCLDLK 73

Query: 358 SGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEE 417
               E+ +              +TG C      W+Y+     C+ F YGGC GN NNF+ 
Sbjct: 74  QDVCEMPK--------------ETGPCLAYFLHWWYDKKDNTCSMFVYGGCQGNNNNFQS 119

Query: 418 EQQCLESCR 426
           +  CL +C+
Sbjct: 120 KANCLNTCK 128


>gi|28212222 WFIKKN2 protein [Homo sapiens]
          Length = 576

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 24/44 (54%), Positives = 26/44 (59%)

Query: 382 GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
           G CK   PRW YN  +  C  F YGGC GN NNFE  + C ESC
Sbjct: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESC 436



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 28/77 (36%), Positives = 37/77 (48%), Gaps = 7/77 (9%)

Query: 257 GRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPSMERRHPVCS 316
           G C+   PRW Y+     C+SFVYGGC GN NN+   E C  +C   +G    R      
Sbjct: 393 GPCKAYAPRWAYNSQTGQCQSFVYGGCEGNGNNFESREACEESCPFPRGNQRCR------ 446

Query: 317 GTCQPTQFRCSNGCCID 333
             C+P Q   ++ C  D
Sbjct: 447 -ACKPRQKLVTSFCRSD 462



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 2/58 (3%)

Query: 368 FPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
           FP+    C+  PD+  C E   RW+++  + +C  FT+G C+ N N+FE  + C+ +C
Sbjct: 323 FPA--AECLKPPDSEDCGEEQTRWHFDAQANNCLTFTFGHCHRNLNHFETYEACMLAC 378



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 12/100 (12%)

Query: 221 QLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVY 280
           Q   TS   P  TA      L    +ED          C     RW++D     C +F +
Sbjct: 309 QAAATSESSPNGTAFPAAECLKPPDSED----------CGEEQTRWHFDAQANNCLTFTF 358

Query: 281 GGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQ 320
           G C  N N++   E C+LAC  + GP      P   G C+
Sbjct: 359 GHCHRNLNHFETYEACMLAC--MSGPLAACSLPALQGPCK 396


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 21/51 (41%), Positives = 30/51 (58%)

Query: 375  CVDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESC 425
            C++    G C E + RWYY+     CARF + GC G+ N F  E++C E+C
Sbjct: 1072 CLEALKPGNCGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETC 1122



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 2/91 (2%)

Query: 215  EGTYLFQLTVTSSDHPEDTANVTVTVLSTKQTEDYCLASNKVGRCRGSFPRWYYDPTEQI 274
            E T+   L  T+S     T    ++       +  CL + K G C     RWYYD     
Sbjct: 1037 EPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNS 1096

Query: 275  CKSFVYGGCLGNKNNYLREEECILACRGVQG 305
            C  F + GC G+ N +  E+EC   C  +QG
Sbjct: 1097 CARFWFSGCNGSGNRFNSEKECQETC--IQG 1125


>gi|93102379 low density lipoprotein-related protein 1B precursor
            [Homo sapiens]
          Length = 4599

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 31/87 (35%), Positives = 41/87 (47%), Gaps = 5/87 (5%)

Query: 283  CLGNKNNYLREEECI---LACRGVQGPSMERRHPVC-SGTCQPTQFRC-SNGCCIDSFLE 337
            CL  +    + ++CI   L C G      E     C   +C P  F+C +   CI     
Sbjct: 3396 CLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDCPENSCSPDYFQCKTTKHCISKLWV 3455

Query: 338  CDDTPNCPDASDEAACEKYTSGFDELQ 364
            CD+ P+C DASDEA C+K T G  E Q
Sbjct: 3456 CDEDPDCADASDEANCDKKTCGPHEFQ 3482



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 18/40 (45%), Positives = 23/40 (57%)

Query: 315  CSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACE 354
            C  +C   QFRCSNG CI +  +CD   +C    DE +CE
Sbjct: 3549 CETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCE 3588



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 33/136 (24%), Positives = 53/136 (38%), Gaps = 16/136 (11%)

Query: 300  CRGVQ--GPSMERRHPVCSGT-------CQPTQFRCSNGCCIDSFLECDDTPNCPDASDE 350
            C G+   G + +  H  C G        C+  +F CSN  CI   L+CD   +C D SDE
Sbjct: 3736 CNGIDECGDNSDEDH--CGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDE 3793

Query: 351  AACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESIPRWYYNPFSEHCAR----FTYG 406
              C    + +     ++   D  +C  +  +  C+   P +  N  +  C        +G
Sbjct: 3794 QGCRIAPTEYTCEDNVNPCGDDAYCNQIKTSVFCR-CKPGFQRNMKNRQCEDLNECLVFG 3852

Query: 407  GCYGNKNNFEEEQQCL 422
             C     N E   +C+
Sbjct: 3853 TCSHQCINVEGSYKCV 3868



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 38/126 (30%), Positives = 53/126 (42%), Gaps = 35/126 (27%)

Query: 271  TEQICKSFVYGGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGC 330
            T+ +CKS   G C+ +K +   +++C        G   +     C  +C   QFRCS+G 
Sbjct: 971  TQFVCKS---GRCISSKWHCDSDDDC--------GDGSDEVG--CVHSCFDNQFRCSSGR 1017

Query: 331  CIDSFLECDDTPNCPDASDEAA--CEKYTSGFDELQRIHFPS----------DKGHCVDL 378
            CI     CD   +C D SDEA   C K        + IH P+            G+CV  
Sbjct: 1018 CIPGHWACDGDNDCGDFSDEAQINCTK--------EEIHSPAGCNGNEFQCHPDGNCV-- 1067

Query: 379  PDTGLC 384
            PD   C
Sbjct: 1068 PDLWRC 1073



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 21/53 (39%), Positives = 29/53 (54%), Gaps = 1/53 (1%)

Query: 299  ACRGVQGPSMERRHPVCSGTCQP-TQFRCSNGCCIDSFLECDDTPNCPDASDE 350
            +CRG +    + R    + +C   ++F C NG CID  L CD  P+C D SDE
Sbjct: 2490 SCRGDRILLEDNRCVTKNSSCNAYSEFECGNGECIDYQLTCDGIPHCKDKSDE 2542



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 17/40 (42%), Positives = 21/40 (52%)

Query: 318  TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYT 357
            TC P +F+C N  CI     CD   +C D SDE  C+  T
Sbjct: 3475 TCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENCKPQT 3514



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 16/36 (44%), Positives = 21/36 (58%)

Query: 318  TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 353
            TC   +FRC++G CI     C+   +C DASDE  C
Sbjct: 2590 TCATVEFRCADGTCIPRSARCNQNIDCADASDEKNC 2625



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/85 (34%), Positives = 36/85 (42%), Gaps = 9/85 (10%)

Query: 305 GPSMERRHPVCSG-TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAA------CEKYT 357
           G + +  +  C+  TCQ  QF C NG CI     CD   +C D +DE A      CE  T
Sbjct: 912 GSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASCEFPTCEPLT 971

Query: 358 SGFDELQRIHFPSDKGHCVDLPDTG 382
               +  R    S K HC    D G
Sbjct: 972 QFVCKSGRC--ISSKWHCDSDDDCG 994



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 21/59 (35%), Positives = 26/59 (44%), Gaps = 6/59 (10%)

Query: 318  TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCV 376
            TC    F C+NG C+ S   CD   +C D SDE  CE   S      +  F    G C+
Sbjct: 3514 TCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNCETSCS------KDQFRCSNGQCI 3566



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 8/77 (10%)

Query: 312  HPVCSG---TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHF 368
            +P C     +C  + F C NG CI S   CD+  +C D SDE  C       +E      
Sbjct: 2881 NPKCKSAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDERNCH-----INECLSKKV 2935

Query: 369  PSDKGHCVDLPDTGLCK 385
                  C DLP +  CK
Sbjct: 2936 SGCSQDCQDLPVSYKCK 2952



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

Query: 319  CQPTQFRCSNG-CCIDSFLECDDTPNCPDASDEAACE-KYTSGFDELQRIHFPSDKGHCV 376
            C   +F C++G C +++  +CD   +CPD SDEA    K  S         F    G C+
Sbjct: 2845 CGTEEFSCADGRCLLNTQWQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFMCKNGRCI 2904

Query: 377  DLPDTGLC 384
              P  GLC
Sbjct: 2905 --PSGGLC 2910



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 19/124 (15%)

Query: 282  GCLGNKNNYLREEECI---LACRGVQGPSMERRHPVCSGTCQ----PTQFRC-SNGCCID 333
            GC GN+     +  C+     C G +          C+GT +     T+F C S G CI+
Sbjct: 1052 GCNGNEFQCHPDGNCVPDLWRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCWSTGRCIN 1111

Query: 334  SFLECDDTPNCPDASDEAACEKYTSGFDE----------LQRIHFPSDKGHCVDLPDTG- 382
                CD   +C D SDE  C+ +  G  +          LQ     + K  C D  D G 
Sbjct: 1112 KAWVCDGDIDCEDQSDEDDCDSFLCGPPKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGY 1171

Query: 383  LCKE 386
            LC E
Sbjct: 1172 LCDE 1175



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 15/36 (41%), Positives = 19/36 (52%)

Query: 315  CSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDE 350
            C   C  +QFRC    CI  + +CD   +C D SDE
Sbjct: 3313 CLSNCTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE 3348



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 15/38 (39%), Positives = 20/38 (52%)

Query: 319  CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKY 356
            CQP +F+C  G C      CD   +C D SDE  C+ +
Sbjct: 3357 CQPGRFQCGTGLCALPAFICDGENDCGDNSDELNCDTH 3394



 Score = 37.0 bits (84), Expect = 0.043
 Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 1/42 (2%)

Query: 315  CSGTCQPTQFRCSNGC-CIDSFLECDDTPNCPDASDEAACEK 355
            C   C+  QFRC N   CI     CD   +C D SDE  CE+
Sbjct: 3628 CVTECKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENCER 3669



 Score = 36.6 bits (83), Expect = 0.056
 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 7/64 (10%)

Query: 316  SGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFP-SDKGH 374
            S TC   ++ C++  CI + L+C+   +C D SDE  C        E +   F   +K H
Sbjct: 3591 SPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDC------VTECKEDQFRCKNKAH 3644

Query: 375  CVDL 378
            C+ +
Sbjct: 3645 CIPI 3648



 Score = 36.2 bits (82), Expect = 0.073
 Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 5/66 (7%)

Query: 319 CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVDL 378
           C+  +FRC N  CI +  +CD   +C D SDE +   +     + Q   F      C+  
Sbjct: 845 CKAGEFRCKNRHCIQARWKCDGDDDCLDGSDEDSVNCFNHSCPDDQ---FKCQNNRCI-- 899

Query: 379 PDTGLC 384
           P   LC
Sbjct: 900 PKRWLC 905



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 18/61 (29%), Positives = 24/61 (39%), Gaps = 4/61 (6%)

Query: 316  SGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHC 375
            + TC    F C N  CI     CD   +C D SDE+       G+ +     F    G C
Sbjct: 2802 NNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDESP----QCGYRQCGTEEFSCADGRC 2857

Query: 376  V 376
            +
Sbjct: 2858 L 2858



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 14/34 (41%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 319 CQPTQFRCSNGC-CIDSFLECDDTPNCPDASDEA 351
           C P +F C +   C+     CD  P+CPD SDE+
Sbjct: 32  CDPGEFLCHDHVTCVSQSWLCDGDPDCPDDSDES 65



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 2/40 (5%)

Query: 319  CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA--ACEKY 356
            C+  +F C+N  C   F  CD   +C D SDEA   C K+
Sbjct: 3674 CRADEFLCNNSLCKLHFWVCDGEDDCGDNSDEAPDMCVKF 3713



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 21/69 (30%), Positives = 27/69 (39%), Gaps = 9/69 (13%)

Query: 318 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA--ACEKYTSGFDELQRIHFPSDKGHC 375
           +C   QF+C N  CI     CD   +C    DE+   C   T   D+     F    G C
Sbjct: 885 SCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDESNQTCTARTCQVDQ-----FSCGNGRC 939

Query: 376 VDLPDTGLC 384
           +  P   LC
Sbjct: 940 I--PRAWLC 946



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 20/59 (33%), Positives = 24/59 (40%), Gaps = 3/59 (5%)

Query: 296  CIL---ACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 351
            CIL    C G +     R    C  +C   QF CS   CI     CD   +C D  DE+
Sbjct: 2694 CILNTWICDGQKDCEDGRDEFHCDSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDES 2752



 Score = 33.1 bits (74), Expect = 0.62
 Identities = 14/40 (35%), Positives = 19/40 (47%)

Query: 319  CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTS 358
            C+   F C +G CI +   CD   +C D  DE  C+   S
Sbjct: 2682 CEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHCDSSCS 2721



 Score = 32.3 bits (72), Expect = 1.1
 Identities = 15/48 (31%), Positives = 20/48 (41%), Gaps = 2/48 (4%)

Query: 305  GPSMERRHPVCSG-TCQPTQFRCSNG-CCIDSFLECDDTPNCPDASDE 350
            G  ++    +C   TC    F C     C+     CD   +CPD SDE
Sbjct: 2746 GDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDE 2793



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 13/100 (13%)

Query: 295  ECI---LACRGV---QGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDAS 348
            ECI   L C G+   +  S E+     + +C+     C N  CI     CD   +C D S
Sbjct: 2522 ECIDYQLTCDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNS 2581

Query: 349  DEAACEKYTSGFDELQRIHFPSDKGHCVDLPDTGLCKESI 388
            DE  C+  T        + F    G C+  P +  C ++I
Sbjct: 2582 DELDCKVSTCA-----TVEFRCADGTCI--PRSARCNQNI 2614


>gi|4507157 sortilin-related receptor containing LDLR class A repeats
            preproprotein [Homo sapiens]
          Length = 2214

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 33/113 (29%), Positives = 45/113 (39%), Gaps = 10/113 (8%)

Query: 272  EQICKSFVYGGCLGNKNNYLREEEC--ILACRGVQGPSMERRHPVCSG------TCQPTQ 323
            E +C  F+   C   +        C  I+ CR   G   +     CS        C    
Sbjct: 1272 EPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCR--DGSDEDAAFAGCSQDPEFHKVCDEFG 1329

Query: 324  FRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCV 376
            F+C NG CI    +CD   +C D SDEA CE  T   +  +   F  + GHC+
Sbjct: 1330 FQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGHCI 1382



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 35/107 (32%), Positives = 43/107 (40%), Gaps = 16/107 (14%)

Query: 318  TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDE--AACEKYTSGFDELQRIHFPSDKGHC 375
            TC+ + F+C NG CI     CD   +C D SDE    CEK  +GF        PS K HC
Sbjct: 1198 TCEASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSK-HC 1256

Query: 376  VDLPDTGLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCL 422
              L D   C +     +  P   H   F            +  QQCL
Sbjct: 1257 DGLRD---CSDGSDEQHCEPLCTHFMDFV----------CKNRQQCL 1290



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 3/61 (4%)

Query: 318  TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCVD 377
            TC   Q+RCSNG CI+S   CD   +C D SDE  C       D   R     + G C+ 
Sbjct: 1077 TCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRC---QESGTCIP 1133

Query: 378  L 378
            L
Sbjct: 1134 L 1134



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 3/58 (5%)

Query: 319  CQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSDKGHCV 376
            C+  ++ CS+G CI S   CD   +C D SDEA C   T+ +   +  +F    GHC+
Sbjct: 1158 CRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANC---TAIYHTCEASNFQCRNGHCI 1212



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 17/36 (47%), Positives = 21/36 (58%)

Query: 318  TCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 353
            TC P  +RCS+G C+     CD   +C D SDE AC
Sbjct: 1418 TCLPNYYRCSSGTCVMDTWVCDGYRDCADGSDEEAC 1453



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 19/42 (45%), Positives = 24/42 (57%), Gaps = 1/42 (2%)

Query: 322  TQFRCS-NGCCIDSFLECDDTPNCPDASDEAACEKYTSGFDE 362
            TQFRC  +G CI    +CD   +C D SDE+ CE +    DE
Sbjct: 1121 TQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDE 1162



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 16/31 (51%), Positives = 19/31 (61%)

Query: 323  QFRCSNGCCIDSFLECDDTPNCPDASDEAAC 353
            QFRC NG CI +  +CD   +C D SDE  C
Sbjct: 1373 QFRCENGHCIPNRWKCDRENDCGDWSDEKDC 1403



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 2/55 (3%)

Query: 318  TCQPTQFRCSNG-CCIDSFLECDDTPNCPDASDEAACEKYTSGFDELQRIHFPSD 371
            TC   +F+C +G  CI     CD   +C D SDE AC    + + ++Q + + +D
Sbjct: 1513 TCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVY-KVQNLQWTAD 1566



 Score = 33.1 bits (74), Expect = 0.62
 Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 1/47 (2%)

Query: 313  PVCSGTCQPTQFRCSNG-CCIDSFLECDDTPNCPDASDEAACEKYTS 358
            P   G C   +F C     CI ++  CD   +C D  DEA C  +++
Sbjct: 1465 PTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDGRDEANCPTHST 1511


>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
           sapiens]
          Length = 241

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 16/113 (14%)

Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGP 306
           ++ C+   + G C     RW++D     C  F Y GC GN NN+L E+ C  AC  +   
Sbjct: 92  QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLI--- 148

Query: 307 SMERRHPVCSGTCQPTQF----RCSNGCCIDSFLECDDTPNCPDASDEAACEK 355
                  V  G C    F     C   C  D  ++C  T  C ++     C +
Sbjct: 149 -------VKDGQCPLFPFTERKECPPSCHSD--IDCPQTDKCCESRCGFVCAR 192



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 18/111 (16%)

Query: 329 GCCIDSFLECDDTPNCPDASD-EAACEKYTSGFDELQRIHFPSDKGHCVD-------LPD 380
           G C    L C  T   PD+ + +  C++Y       Q+  F + +  C+D       LP 
Sbjct: 49  GLCPKERLTC--TTELPDSCNTDFDCKEY-------QKCCFFACQKKCMDPFQEPCMLPV 99

Query: 381 T-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISK 430
             G C     RW+++  +  C  F Y GC GN NNF  E  C  +C  I K
Sbjct: 100 RHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150


>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
           sapiens]
          Length = 241

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 16/113 (14%)

Query: 247 EDYCLASNKVGRCRGSFPRWYYDPTEQICKSFVYGGCLGNKNNYLREEECILACRGVQGP 306
           ++ C+   + G C     RW++D     C  F Y GC GN NN+L E+ C  AC  +   
Sbjct: 92  QEPCMLPVRHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLI--- 148

Query: 307 SMERRHPVCSGTCQPTQF----RCSNGCCIDSFLECDDTPNCPDASDEAACEK 355
                  V  G C    F     C   C  D  ++C  T  C ++     C +
Sbjct: 149 -------VKDGQCPLFPFTERKECPPSCHSD--IDCPQTDKCCESRCGFVCAR 192



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 34/111 (30%), Positives = 48/111 (43%), Gaps = 18/111 (16%)

Query: 329 GCCIDSFLECDDTPNCPDASD-EAACEKYTSGFDELQRIHFPSDKGHCVD-------LPD 380
           G C    L C  T   PD+ + +  C++Y       Q+  F + +  C+D       LP 
Sbjct: 49  GLCPKERLTC--TTELPDSCNTDFDCKEY-------QKCCFFACQKKCMDPFQEPCMLPV 99

Query: 381 T-GLCKESIPRWYYNPFSEHCARFTYGGCYGNKNNFEEEQQCLESCRGISK 430
             G C     RW+++  +  C  F Y GC GN NNF  E  C  +C  I K
Sbjct: 100 RHGNCNHEAQRWHFDFKNYRCTPFKYRGCEGNANNFLNEDACRTACMLIVK 150


>gi|61744471 low density lipoprotein receptor-related protein 8
           isoform 1 precursor [Homo sapiens]
          Length = 963

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 14/75 (18%)

Query: 302 GVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFD 361
           G QGP+ +         C+  QF+C N  CI S   CD+  +C D SDE  C K T    
Sbjct: 39  GGQGPAKD---------CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADS 89

Query: 362 ELQRIHFPSDKGHCV 376
           +     F  D GHC+
Sbjct: 90  D-----FTCDNGHCI 99



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 16/37 (43%), Positives = 24/37 (64%)

Query: 317 GTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 353
           GTC+  +F+C +G C+ +   C+   +CPD SDEA C
Sbjct: 297 GTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 333



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 318 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASD--EAACEKYTSGFDEL 363
           TC  + F C NG CI    +CD    CPD SD  EA C K     ++L
Sbjct: 85  TCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKL 132



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 15/39 (38%), Positives = 21/39 (53%)

Query: 315 CSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 353
           C+  C P +F+C N  C+ +   CD   +C D SDE  C
Sbjct: 163 CATLCAPHEFQCGNRSCLAAVFVCDGDDDCGDGSDERGC 201



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 31/111 (27%), Positives = 42/111 (37%), Gaps = 12/111 (10%)

Query: 292 REEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEA 351
           R +E    C G  GP        C+     +QF C +G C+     CD   +C D SDEA
Sbjct: 237 RSDEAAELC-GRPGPGATSAPAACATA---SQFACRSGECVHLGWRCDGDRDCKDKSDEA 292

Query: 352 ACEKYTSGFDELQ--------RIHFPSDKGHCVDLPDTGLCKESIPRWYYN 394
            C   T   DE Q         I   + +  C D  D   C + +    +N
Sbjct: 293 DCPLGTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGCLQGLNECLHN 343



 Score = 34.3 bits (77), Expect = 0.28
 Identities = 17/37 (45%), Positives = 19/37 (51%), Gaps = 3/37 (8%)

Query: 319 CQPTQFRCSN---GCCIDSFLECDDTPNCPDASDEAA 352
           C P +FRC     G CI     CD   +C D SDEAA
Sbjct: 206 CGPREFRCGGDGGGACIPERWVCDRQFDCEDRSDEAA 242



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 281 GGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDD 340
           G C+  +     EEEC       +    ++  P    +C PT  +C     + +   CD 
Sbjct: 96  GHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKC-----VPASWRCDG 150

Query: 341 TPNCPDASDEAAC 353
             +C   +DEA C
Sbjct: 151 EKDCEGGADEAGC 163


>gi|61744467 low density lipoprotein receptor-related protein 8
           isoform 3 precursor [Homo sapiens]
          Length = 700

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 14/75 (18%)

Query: 302 GVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFD 361
           G QGP+ +         C+  QF+C N  CI S   CD+  +C D SDE  C K T    
Sbjct: 39  GGQGPAKD---------CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADS 89

Query: 362 ELQRIHFPSDKGHCV 376
           +     F  D GHC+
Sbjct: 90  D-----FTCDNGHCI 99



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 16/37 (43%), Positives = 24/37 (64%)

Query: 317 GTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAAC 353
           GTC+  +F+C +G C+ +   C+   +CPD SDEA C
Sbjct: 168 GTCRGDEFQCGDGTCVLAIKHCNQEQDCPDGSDEAGC 204



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 318 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASD--EAACEKYTSGFDEL 363
           TC  + F C NG CI    +CD    CPD SD  EA C K     ++L
Sbjct: 85  TCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKL 132



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 281 GGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDD 340
           G C+  +     EEEC       +    ++  P    +C PT  +C     + +   CD 
Sbjct: 96  GHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKC-----VPASWRCDG 150

Query: 341 TPNCPDASDEAAC 353
             +C   +DEA C
Sbjct: 151 EKDCEGGADEAGC 163


>gi|66082554 low density lipoprotein receptor-related protein 8
           isoform 2 precursor [Homo sapiens]
          Length = 793

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 27/75 (36%), Positives = 35/75 (46%), Gaps = 14/75 (18%)

Query: 302 GVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDDTPNCPDASDEAACEKYTSGFD 361
           G QGP+ +         C+  QF+C N  CI S   CD+  +C D SDE  C K T    
Sbjct: 39  GGQGPAKD---------CEKDQFQCRNERCIPSVWRCDEDDDCLDHSDEDDCPKKTCADS 89

Query: 362 ELQRIHFPSDKGHCV 376
           +     F  D GHC+
Sbjct: 90  D-----FTCDNGHCI 99



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 2/48 (4%)

Query: 318 TCQPTQFRCSNGCCIDSFLECDDTPNCPDASD--EAACEKYTSGFDEL 363
           TC  + F C NG CI    +CD    CPD SD  EA C K     ++L
Sbjct: 85  TCADSDFTCDNGHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKL 132



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 18/73 (24%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 281 GGCLGNKNNYLREEECILACRGVQGPSMERRHPVCSGTCQPTQFRCSNGCCIDSFLECDD 340
           G C+  +     EEEC       +    ++  P    +C PT  +C     + +   CD 
Sbjct: 96  GHCIHERWKCDGEEECPDGSDESEATCTKQVCPAEKLSCGPTSHKC-----VPASWRCDG 150

Query: 341 TPNCPDASDEAAC 353
             +C   +DEA C
Sbjct: 151 EKDCEGGADEAGC 163


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,069,525
Number of Sequences: 37866
Number of extensions: 1262556
Number of successful extensions: 5182
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 4726
Number of HSP's gapped (non-prelim): 429
length of query: 513
length of database: 18,247,518
effective HSP length: 107
effective length of query: 406
effective length of database: 14,195,856
effective search space: 5763517536
effective search space used: 5763517536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.