Guide to the Human Genome
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Search of human proteins with 73858561

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo
sapiens]
         (333 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo sa...   657   0.0  
gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo sa...   657   0.0  
gi|73858559 proline/serine-rich coiled-coil 1 isoform c [Homo sa...   641   0.0  
gi|52630338 proline/serine-rich coiled-coil 1 isoform b [Homo sa...   422   e-118
gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]                55   9e-08
gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens]                55   1e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         54   2e-07
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    52   7e-07
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    52   7e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   51   1e-06
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   51   1e-06
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   51   1e-06
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    51   1e-06
gi|239741585 PREDICTED: hypothetical protein XP_002342243 [Homo ...    50   2e-06
gi|150170729 microtubule associated serine/threonine kinase 3 [H...    50   3e-06
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                49   6e-06
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                49   6e-06
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                49   6e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    49   8e-06
gi|18959210 WIRE protein [Homo sapiens]                                49   8e-06
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap...    47   2e-05
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap...    47   2e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               47   2e-05
gi|33356148 formin-like 1 [Homo sapiens]                               47   2e-05
gi|223633988 hypothetical protein LOC85379 [Homo sapiens]              47   2e-05
gi|239752069 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo ...    47   2e-05
gi|239746566 PREDICTED: hypothetical protein XP_002343789 [Homo ...    47   2e-05
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]          47   2e-05
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]          47   2e-05

>gi|73858561 proline/serine-rich coiled-coil 1 isoform a [Homo
           sapiens]
          Length = 333

 Score =  657 bits (1695), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60
           MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ
Sbjct: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60

Query: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120
           GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK
Sbjct: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120

Query: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180
           DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL
Sbjct: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180

Query: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAA 240
           FPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAA
Sbjct: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAA 240

Query: 241 AKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGH 300
           AKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGH
Sbjct: 241 AKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGH 300

Query: 301 KVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR 333
           KVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR
Sbjct: 301 KVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR 333


>gi|14249168 proline/serine-rich coiled-coil 1 isoform a [Homo
           sapiens]
          Length = 333

 Score =  657 bits (1695), Expect = 0.0
 Identities = 333/333 (100%), Positives = 333/333 (100%)

Query: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60
           MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ
Sbjct: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60

Query: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120
           GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK
Sbjct: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120

Query: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180
           DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL
Sbjct: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180

Query: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAA 240
           FPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAA
Sbjct: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAA 240

Query: 241 AKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGH 300
           AKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGH
Sbjct: 241 AKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGH 300

Query: 301 KVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR 333
           KVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR
Sbjct: 301 KVPVSQRLNLPVMGATRSNLQPPRKVAVPGPTR 333


>gi|73858559 proline/serine-rich coiled-coil 1 isoform c [Homo
           sapiens]
          Length = 363

 Score =  641 bits (1654), Expect = 0.0
 Identities = 333/363 (91%), Positives = 333/363 (91%), Gaps = 30/363 (8%)

Query: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60
           MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ
Sbjct: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60

Query: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120
           GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK
Sbjct: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120

Query: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180
           DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL
Sbjct: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180

Query: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAAS---------------------------- 212
           FPASKSPASSPLTRSTPPVRGRAGPSGRAAAS                            
Sbjct: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAASEETRAAKLRVSGSGEFVGLTLKFLHPSP 240

Query: 213 --PPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPG 270
             PPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPG
Sbjct: 241 PGPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPG 300

Query: 271 RGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPG 330
           RGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPG
Sbjct: 301 RGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPG 360

Query: 331 PTR 333
           PTR
Sbjct: 361 PTR 363


>gi|52630338 proline/serine-rich coiled-coil 1 isoform b [Homo
           sapiens]
          Length = 310

 Score =  422 bits (1086), Expect = e-118
 Identities = 216/229 (94%), Positives = 220/229 (96%)

Query: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60
           MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ
Sbjct: 1   MEDLEEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQ 60

Query: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120
           GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK
Sbjct: 61  GVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLK 120

Query: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180
           DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL
Sbjct: 121 DSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNL 180

Query: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSN 229
           FPASKSPASSPLTRSTPPVRGRAGPSGRAAAS  T    + A QP+ ++
Sbjct: 181 FPASKSPASSPLTRSTPPVRGRAGPSGRAAASEETRAAKLRACQPNATH 229


>gi|5031587 adenomatosis polyposis coli 2 [Homo sapiens]
          Length = 2303

 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 57/196 (29%), Positives = 78/196 (39%), Gaps = 17/196 (8%)

Query: 139  PSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPP 198
            PSP     R      K S  A  +   +  +   R + T +   +  SPAS PL R  PP
Sbjct: 1833 PSPGQQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPP 1892

Query: 199  VRGRAG--PSGRAAASPPTPIRSVLAPQPSTSNSQ-RLPRPQGAAAKSSSQLPIPSAIPR 255
            V   AG  P   A+  P TP R++LA Q  T  S  R+P  Q  A +     P+  A+P 
Sbjct: 1893 VTQAAGALPGPGASPVPKTPARTLLAKQHKTQRSPVRIPFMQRPARRGPP--PLARAVPE 1950

Query: 256  PASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNL----P 311
            P  R    + + P  RG         R GL R ++A     ES  +    ++L      P
Sbjct: 1951 PGPRGRAGTEAGPGARGG--------RLGLVRVASALSSGSESSDRSGFRRQLTFIKESP 2002

Query: 312  VMGATRSNLQPPRKVA 327
             +   RS L      A
Sbjct: 2003 GLRRRRSELSSAESAA 2018



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 72/297 (24%), Positives = 107/297 (36%), Gaps = 23/297 (7%)

Query: 12   VDETLDFGGLSPSDSREEEDITVLVTPEKP-LRRGLSHRSDPNAVAPAPQGVRLSLGP-- 68
            V   L  G  S   S     +T +   E P LRR  S  S   + A APQG     G   
Sbjct: 1975 VASALSSGSESSDRSGFRRQLTFI--KESPGLRRRRSELSSAESAASAPQGASPRRGRPA 2032

Query: 69   -----LSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRR---ETFVLK 120
                 L   + EE+     +  A   Q     R S GE    R    SP R        +
Sbjct: 2033 LPAVFLCSSRCEELRAAPRQGPAPARQRPPAARPSPGERPARRTTSESPSRLPVRAPAAR 2092

Query: 121  DSPVRDL--LPTVNSLTRST----PSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRE 174
               V+    LP ++   R       +P+S     RS+D  G  R L   +    +  +  
Sbjct: 2093 PETVKRYASLPHISVARRPDGAVPAAPASADAARRSSD--GEPRPLPRVAAPGTTWRRIR 2150

Query: 175  SPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLP 234
                     S  PA++   R + P    AGP  R  +        V AP+ ++S S  L 
Sbjct: 2151 DEDVPHILRSTLPATALPLRGSTPEDAPAGPPPRKTSDAVVQTEEVAAPKTNSSTSPSLE 2210

Query: 235  RPQGAAAKSSSQLP-IPSAIPRPA-SRMPLTSRSVPPGRGALPPDSLSTRKGLPRPS 289
              +   A +  QL  + S +  P+ ++ P+++  V  G G       ++R G P  S
Sbjct: 2211 TREPPGAPAGGQLSLLGSDVDGPSLAKAPISAPFVHEGLGVAVGGFPASRHGSPSRS 2267



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 88/361 (24%), Positives = 119/361 (32%), Gaps = 79/361 (21%)

Query: 22   SPSDSREEEDITVLVTPEKPLRR----GLSHRSDPNAVAPAPQGVRLSLGPL--SPEKLE 75
            SPS    EE +   ++   P RR    GL  R         P+  RL   P   S E+ E
Sbjct: 1619 SPSPRAAEELLQRCISSALPRRRPPVSGLRRRK--------PRATRLDERPAEGSRERGE 1670

Query: 76   E-----------------ILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFV 118
            E                 I + AN +   L Q A   RE++ E         S    +FV
Sbjct: 1671 EAAGSDRASDLDSVEWRAIQEGANSIVTWLHQAAAATREASSE---------SDSILSFV 1721

Query: 119  LKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTC 178
               S    L P  +   R            R  +++G+     + S + P+  ++   T 
Sbjct: 1722 SGLSVGSTLQPPKHRKGRQAEGEMGSA---RRPEKRGAASVKTSGSPRSPAGPEKPRGTQ 1778

Query: 179  NLFPASKSP--------ASSPLTRSTPPVRGRAGPSG--RAAASP--PTPIRSVLAPQPS 226
               P   +           SP  R+ P  +G  GP    R  A P    P      P P 
Sbjct: 1779 KTTPGVPAVLRGRTVIYVPSPAPRAQP--KGTPGPRATPRKVAPPCLAQPAAPAKVPSPG 1836

Query: 227  TSNSQRLPRPQGAAAKSSSQLPIPSAIP------RPASRMPLTS-------RSVPP---G 270
               S+ L RP   +  ++   P  SA P       P+S    TS       R  PP    
Sbjct: 1837 QQRSRSLHRPAKTSELATLSQPPRSATPPARLAKTPSSSSSQTSPASQPLPRKRPPVTQA 1896

Query: 271  RGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPG 330
             GALP    S     P P T    +    HK   S  + +P M        PP   AVP 
Sbjct: 1897 AGALPGPGAS-----PVPKTPARTLLAKQHKTQRSP-VRIPFMQRPARRGPPPLARAVPE 1950

Query: 331  P 331
            P
Sbjct: 1951 P 1951


>gi|253970412 G-2 and S-phase expressed 1 [Homo sapiens]
          Length = 739

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 87/355 (24%), Positives = 132/355 (37%), Gaps = 65/355 (18%)

Query: 5   EEDVRFIVDETLDFGGLSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRL 64
           +ED+  + DE  DF  LS S S   ED  V   P     R ++   + N   P    +  
Sbjct: 25  KEDILLLADEKFDFD-LSLSSSSANEDDEVFFGPFGHKERCIAASLELNNPVPEQPPLPT 83

Query: 65  S-----LGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPR------------- 106
           S       PL+ EK  E+  EA+ LA  +E  +      A +   PR             
Sbjct: 84  SESPFAWSPLAGEKFVEVYKEAHLLALHIESSSRNQAAQAAKPEDPRSQGVERFIQESKL 143

Query: 107 ---------RVKPSP---RRETFVLKDSPVRDLLPTVNS--LTRSTPSPSSLTPRLRSND 152
                     +K SP   +RET+ L DSP+  L P V    L  S+P+  S   + R   
Sbjct: 144 KINLFEKEKEMKKSPTSLKRETYYLSDSPL--LGPPVGEPRLLASSPALPSSGAQARLTR 201

Query: 153 RKGSVRALRATSGKRPSNMKRESPTCNL---FPASKSPASSPLTRSTPPVRGRAGPSGRA 209
             G   +  A        + RES T +        + P +  L      VRGR+ P   A
Sbjct: 202 APGPPHSAHA--------LPRESCTAHAASQAATQRKPGTKLLLPRAASVRGRSIPG--A 251

Query: 210 AASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
           A  P   I       P++ +  ++P     A K S +  +P      A  +P     +  
Sbjct: 252 AEKPKKEI-------PASPSRTKIP-----AEKESHRDVLPDKPAPGAVNVPAAGSHLGQ 299

Query: 270 GRGALP-PDSLSTRKGLPRPSTAGHRVRESGHKVPV----SQRLNLPVMGATRSN 319
           G+ A+P P+ L  +K L +   +   +       PV    S     P +G  +S+
Sbjct: 300 GKRAIPVPNKLGLKKTLLKAPGSTSNLARKSSSGPVWSGASSACTSPAVGKAKSS 354


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 81/319 (25%), Positives = 119/319 (37%), Gaps = 31/319 (9%)

Query: 22  SPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEA 81
           +P  S       V V+P +   +   H+      +P+P     +  P   E  E   D+ 
Sbjct: 416 TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP-----APKPRKVELSESEEDKG 470

Query: 82  NRLAA-----QLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTR 136
            ++AA     Q  Q   Q+++S+ +  G        R +   +K+  V           R
Sbjct: 471 GKMAAADSVQQRRQYRRQNQQSSSDS-GSSSSSEDERPKRSHVKNGEV-------GRRRR 522

Query: 137 STPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRST 196
            +PS S+ +P  R   ++ S R  R  S   P   +R SP+    P  +   + P  R T
Sbjct: 523 HSPSRSA-SPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581

Query: 197 P-PVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPR 255
           P P   R  PS R   SPP   R   +P P    +   P P+  A+      P P    R
Sbjct: 582 PSPPPRRRSPSPR-RYSPPIQRRYSPSPPPKRRTASPPPPPKRRAS------PSPPPKRR 634

Query: 256 PASRMPLTSRSVPPGRGALPPDSLSTRKG-LPRPSTAGHRVRESGHKVPVSQRLNLPVMG 314
            +   P   RS P  +   P  S   RKG  P  ST   R  +   +   S R   P   
Sbjct: 635 VSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP--- 691

Query: 315 ATRSNLQPPRKVAVPGPTR 333
            T S+  P R+ A   P R
Sbjct: 692 QTSSSPPPVRRGASSSPQR 710



 Score = 49.3 bits (116), Expect = 5e-06
 Identities = 53/184 (28%), Positives = 72/184 (39%), Gaps = 37/184 (20%)

Query: 106 RRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSG 165
           RR  PSP  +  V    P +          RS+P     +P L S  RKGS  +      
Sbjct: 623 RRASPSPPPKRRVSHSPPPKQ---------RSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673

Query: 166 KRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP 225
           + P   KR SP+    P  ++P +S    S PPVR       R A+S P   +S   P P
Sbjct: 674 RSPQPNKRHSPS----PRPRAPQTSS---SPPPVR-------RGASSSPQRRQS---PSP 716

Query: 226 STSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGL 285
           ST   +R+           S+ P P  I + AS  P + R V   R        + +K  
Sbjct: 717 STRPIRRV-----------SRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPP 765

Query: 286 PRPS 289
             PS
Sbjct: 766 APPS 769



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 65/280 (23%), Positives = 110/280 (39%), Gaps = 40/280 (14%)

Query: 44  RGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRESAGEGL 103
           R   HR+   + +PAP+           EK  E+ + +     ++++ ++Q+  S  + L
Sbjct: 199 RSPRHRTKSRSPSPAPE---------KKEKTPELPEPS----VKVKEPSVQEATSTSDIL 245

Query: 104 G-------PRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRS---TPSPSSLTPRLRSNDR 153
                   P   +PSP + +   K+           S +RS   + SPS   PR R   R
Sbjct: 246 KVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305

Query: 154 KGSVRALRATSGKRPSNMKRESPTCNLFPASKSPAS-SPLTRSTPPVRGRAGPSGRAAA- 211
             S    R  S +R  + +R +P   + P  +   S SP+ R        +G S  +++ 
Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS 365

Query: 212 ---SPP--------TPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRM 260
              SPP        +P R      PS S  +R  RP   A         P+  P+ ++R 
Sbjct: 366 RSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPT--PQQSNRT 423

Query: 261 PLTSRSVPPGR--GALPPDSLSTRKGLPRPSTAGHRVRES 298
             +  SV PGR  G +     + ++  P P+    +V  S
Sbjct: 424 RKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS 463



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 53/239 (22%), Positives = 88/239 (36%), Gaps = 27/239 (11%)

Query: 22  SPSDSREEEDITVLVTPEKPLRRGLSHRSDP---NAVAPAPQGVRLSLGPLSPEKLEEIL 78
           SPS  R    I    +P  P +R  +    P    A    P   R+S  P   ++   + 
Sbjct: 590 SPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVT 649

Query: 79  DEANRLAAQLEQCALQDRESAGEGLGP---RRVKPSPRRETFVLKDSPVRDLLPTVNSLT 135
              +   +   +       S  E   P   +R  PSPR        SP     P V    
Sbjct: 650 KRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSP-----PPVRRGA 704

Query: 136 RSTP----SPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLF----PASKSP 187
            S+P    SPS  T  +R   R    + ++  +   P +++R S + ++     PA+K P
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764

Query: 188 ASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQ 246
            + P      PV+ ++  +     SP  P++   +P PS S  +   +  G   K   +
Sbjct: 765 PAPP-----SPVQSQSPSTNW---SPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKK 815



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 48/196 (24%), Positives = 72/196 (36%), Gaps = 23/196 (11%)

Query: 150 SNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRA 209
           S +++   R+ R    + PS  +R SP       S S +    T+S  P    +    + 
Sbjct: 162 SREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSP----SPAPEKK 217

Query: 210 AASPPTPIRSVLAPQPS----TSNS--------QRLPRPQGAAAKSSSQLPIPSAIPRPA 257
             +P  P  SV   +PS    TS S        + +P P+  + + +S+        RP 
Sbjct: 218 EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277

Query: 258 SRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATR 317
           SR    SRS    R   P  +   R+   R  +   R R S  + P  +R   P     R
Sbjct: 278 SRSRSKSRSRTRSRS--PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP-----R 330

Query: 318 SNLQPPRKVAVPGPTR 333
               PPR      P R
Sbjct: 331 RMPPPPRHRRSRSPVR 346


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 67/226 (29%), Positives = 85/226 (37%), Gaps = 41/226 (18%)

Query: 104 GPRRVKPSPRRETF------VLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSV 157
           GPR+  P P    F       L    +R   P  +S   S   P   TP    +D+    
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQS-PLSSSSPFSNRPPLPPTPSRALDDKPPPP 267

Query: 158 RALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPI 217
                  G RPS  +   P              P   + PPV     PS  + A PP P 
Sbjct: 268 PP---PVGNRPSIHREAVPP------------PPPQNNKPPVPSTPRPSASSQAPPPPPP 312

Query: 218 RSVLAP---QPSTSNSQRLPR-PQGAAAKSSSQLPIPS-----AIPRPASRMPLTSRSVP 268
            S   P    PS+S +   PR PQ   + SSS  P+PS      +P P S  P      P
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372

Query: 269 PGR-GALPPD-----SLSTRKGLPR----PSTAGHRVRESGHKVPV 304
           PGR G LPP      + ST + LP     PS +G     SG + P+
Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 55/186 (29%), Positives = 71/186 (38%), Gaps = 29/186 (15%)

Query: 109 KPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSG--K 166
           +PS  RE   +   P ++  P V S  R + S S   P      R G      ++SG  +
Sbjct: 274 RPSIHREA--VPPPPPQNNKPPVPSTPRPSAS-SQAPPPPPPPSRPGPPPLPPSSSGNDE 330

Query: 167 RPSNMKRESPTCNLFPASKSPASS------PLTRSTPPVRGRAGPSGRAAASPPTPIRSV 220
            P   +R     +  P   SP  S      P  R  PPVR    P GR+   PP P  S 
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD---PPGRSGPLPPPPPVS- 386

Query: 221 LAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAI--PRPASRMPLTSRSVPPGRGALPPDS 278
                + S S+ LP        ++ QLP  S +  PR   R PL       G    PP S
Sbjct: 387 ----RNGSTSRALP--------ATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434

Query: 279 LSTRKG 284
            S R G
Sbjct: 435 TSIRNG 440



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 46/177 (25%), Positives = 69/177 (38%), Gaps = 35/177 (19%)

Query: 160 LRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRS 219
           LR+T+ +   +     P   L P  +S ++ P +  + P R    PS    + PP P R+
Sbjct: 111 LRSTANRDNDSGGSRPPL--LPPGGRSTSAKPFSPPSGPGRFPV-PSPGHRSGPPEPQRN 167

Query: 220 VLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSL 279
            + P          PRP   +   S   P+PS  PRP        +S P  RG+ PP   
Sbjct: 168 RMPP----------PRPDVGSKPDSIPPPVPST-PRPI-------QSSPHNRGS-PPVPG 208

Query: 280 STRKGLPRP-----------STAGHRVRES--GHKVPVSQRLNLPVMGATRSNLQPP 323
             R+  P P           +  G  +R+S      P S R  LP   +   + +PP
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 47/189 (24%), Positives = 66/189 (34%), Gaps = 55/189 (29%)

Query: 182 PASKSPA-SSPLTRSTPPV-------------------RGRAGPSGRAAASP-----PTP 216
           P++  P  SSP  R +PPV                   RG A   G    SP     P  
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS 247

Query: 217 IRSVLAPQPSTSNSQRLPRPQGAAAK--------------SSSQLPIPSAIPRPASRMPL 262
            R  L P PS +   + P P                     +++ P+PS  PRP++    
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST-PRPSASSQA 306

Query: 263 TSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP 322
                PP R   PP        LP PS++G+       + P   + NL +  +T     P
Sbjct: 307 PPPPPPPSRPGPPP--------LP-PSSSGN------DETPRLPQRNLSLSSSTPPLPSP 351

Query: 323 PRKVAVPGP 331
            R   +P P
Sbjct: 352 GRSGPLPPP 360


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 67/226 (29%), Positives = 85/226 (37%), Gaps = 41/226 (18%)

Query: 104 GPRRVKPSPRRETF------VLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSV 157
           GPR+  P P    F       L    +R   P  +S   S   P   TP    +D+    
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQS-PLSSSSPFSNRPPLPPTPSRALDDKPPPP 267

Query: 158 RALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPI 217
                  G RPS  +   P              P   + PPV     PS  + A PP P 
Sbjct: 268 PP---PVGNRPSIHREAVPP------------PPPQNNKPPVPSTPRPSASSQAPPPPPP 312

Query: 218 RSVLAP---QPSTSNSQRLPR-PQGAAAKSSSQLPIPS-----AIPRPASRMPLTSRSVP 268
            S   P    PS+S +   PR PQ   + SSS  P+PS      +P P S  P      P
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP 372

Query: 269 PGR-GALPPD-----SLSTRKGLPR----PSTAGHRVRESGHKVPV 304
           PGR G LPP      + ST + LP     PS +G     SG + P+
Sbjct: 373 PGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPL 418



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 55/186 (29%), Positives = 71/186 (38%), Gaps = 29/186 (15%)

Query: 109 KPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSG--K 166
           +PS  RE   +   P ++  P V S  R + S S   P      R G      ++SG  +
Sbjct: 274 RPSIHREA--VPPPPPQNNKPPVPSTPRPSAS-SQAPPPPPPPSRPGPPPLPPSSSGNDE 330

Query: 167 RPSNMKRESPTCNLFPASKSPASS------PLTRSTPPVRGRAGPSGRAAASPPTPIRSV 220
            P   +R     +  P   SP  S      P  R  PPVR    P GR+   PP P  S 
Sbjct: 331 TPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRD---PPGRSGPLPPPPPVS- 386

Query: 221 LAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAI--PRPASRMPLTSRSVPPGRGALPPDS 278
                + S S+ LP        ++ QLP  S +  PR   R PL       G    PP S
Sbjct: 387 ----RNGSTSRALP--------ATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434

Query: 279 LSTRKG 284
            S R G
Sbjct: 435 TSIRNG 440



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 46/177 (25%), Positives = 69/177 (38%), Gaps = 35/177 (19%)

Query: 160 LRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRS 219
           LR+T+ +   +     P   L P  +S ++ P +  + P R    PS    + PP P R+
Sbjct: 111 LRSTANRDNDSGGSRPPL--LPPGGRSTSAKPFSPPSGPGRFPV-PSPGHRSGPPEPQRN 167

Query: 220 VLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSL 279
            + P          PRP   +   S   P+PS  PRP        +S P  RG+ PP   
Sbjct: 168 RMPP----------PRPDVGSKPDSIPPPVPST-PRPI-------QSSPHNRGS-PPVPG 208

Query: 280 STRKGLPRP-----------STAGHRVRES--GHKVPVSQRLNLPVMGATRSNLQPP 323
             R+  P P           +  G  +R+S      P S R  LP   +   + +PP
Sbjct: 209 GPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265



 Score = 31.2 bits (69), Expect = 1.3
 Identities = 47/189 (24%), Positives = 66/189 (34%), Gaps = 55/189 (29%)

Query: 182 PASKSPA-SSPLTRSTPPV-------------------RGRAGPSGRAAASP-----PTP 216
           P++  P  SSP  R +PPV                   RG A   G    SP     P  
Sbjct: 188 PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFS 247

Query: 217 IRSVLAPQPSTSNSQRLPRPQGAAAK--------------SSSQLPIPSAIPRPASRMPL 262
            R  L P PS +   + P P                     +++ P+PS  PRP++    
Sbjct: 248 NRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPST-PRPSASSQA 306

Query: 263 TSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP 322
                PP R   PP        LP PS++G+       + P   + NL +  +T     P
Sbjct: 307 PPPPPPPSRPGPPP--------LP-PSSSGN------DETPRLPQRNLSLSSSTPPLPSP 351

Query: 323 PRKVAVPGP 331
            R   +P P
Sbjct: 352 GRSGPLPPP 360


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/302 (20%), Positives = 105/302 (34%), Gaps = 29/302 (9%)

Query: 35  LVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQ 94
           + TP+    +     + P      P   R SL P S    E  L        + ++    
Sbjct: 99  VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 158

Query: 95  DRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRK 154
           +++++ +G    + K +  +ET  ++ +  +DL PT   L + TP   + T         
Sbjct: 159 NKQTSTDG----KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT----KGPAL 210

Query: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSP---LTRSTPPVRGRAGPSGRAAA 211
            + +    T+ K P++   + PT     ++ +    P    T+S P       P+     
Sbjct: 211 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 270

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGR 271
           +P TP      P P+T+       P     KS+   P   A   P    P T +   P  
Sbjct: 271 APTTP----KEPAPTTTK-----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP-- 319

Query: 272 GALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPG 330
              P +   T    P P+T     +E     P       P   A  +  +P P     P 
Sbjct: 320 -TTPKEPTPTTPKEPAPTT-----KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373

Query: 331 PT 332
           PT
Sbjct: 374 PT 375



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 54/266 (20%), Positives = 95/266 (35%), Gaps = 27/266 (10%)

Query: 37  TPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDR 96
           TP++P        +      PAP   +    P +P+KL     E  +LA    +   +  
Sbjct: 454 TPKEPAPTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPTTPE--KLAPTTPE---KPA 507

Query: 97  ESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGS 156
            +  E L P     +P   T    + P           T   P+P++      +  ++ +
Sbjct: 508 PTTPEELAPT----TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563

Query: 157 VRALRATS-----GKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAA 211
               + T+     G  P+ +K  +PT    PA K  A +     T     +  P+     
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAA-------AKSSSQLPIPSAIPRPASRMPLTS 264
           +P TP      P P+T        P+G A       A ++ + P P  +    ++ P ++
Sbjct: 624 APTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 679

Query: 265 RSVPPGRGALPPDSLSTRKGLPRPST 290
            S  P     P ++  T    P P+T
Sbjct: 680 TSDKPA-PTTPKETAPTTPKEPAPTT 704



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 43/177 (24%), Positives = 64/177 (36%), Gaps = 14/177 (7%)

Query: 168 PSNMKRESPTCNLFPASKSPASSPLT---RSTPPVRGRAGPSGRAAASPPTPIR-SVLAP 223
           P+  K+ +PT    PA  +P  +  T   + TP    +  P+     +P TP   +   P
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519

Query: 224 QPSTSNSQRLPRPQG--AAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGA--LPPDSL 279
           +  T  +   P P    AAA ++ + P P+    PA   P       P   A   P  + 
Sbjct: 520 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579

Query: 280 STRKGLPRPST----AGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPGPT 332
            T    P P+T    A   +  +  K P S   + P    T      P     P PT
Sbjct: 580 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP--APTTPKGTAPTTPKEPAPT 634



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 47/228 (20%), Positives = 75/228 (32%), Gaps = 22/228 (9%)

Query: 110 PSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPS 169
           P     T   + +P     P   +     P+ +   P         + +    T+ K P+
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 318

Query: 170 --NMKRESPTCNLFPA--SKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP 225
               K  +PT    PA  +K PA +      P    +  P+     +P TP      P P
Sbjct: 319 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAP 374

Query: 226 STSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGL 285
           +T+       P+  A  ++   P  +  P P      T++S P      P +   T    
Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT-----TTKSAP----TTPKEPSPTTTKE 425

Query: 286 PRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPGPT 332
           P P+T     +E     P       P   A  +  +P P     P PT
Sbjct: 426 PAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 469



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 46/203 (22%), Positives = 70/203 (34%), Gaps = 35/203 (17%)

Query: 135 TRSTPSPSSLTPRLRSNDRKGSVRALRATS--GKRPSNMKRESPTCNLFPASKSP-ASSP 191
           T   P+P  L P         +      T+  G  P+  K  +PT    PA  +P  ++P
Sbjct: 590 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649

Query: 192 LTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP-----STSNSQRLPRPQGAAAKSSSQ 246
            T   P           A  +P  P    LAP       ST++ +  P      A ++ +
Sbjct: 650 TTLKEP-----------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 698

Query: 247 LPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQ 306
            P P+   +PA   P T  + PP         +ST      P+T         HK P   
Sbjct: 699 EPAPTTPKKPA---PTTPETPPP-----TTSEVSTPTTTKEPTTI--------HKSPDES 742

Query: 307 RLNLPVMGATRSNLQPPRKVAVP 329
              L      ++    P++  VP
Sbjct: 743 TPELSAEPTPKALENSPKEPGVP 765



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/176 (23%), Positives = 62/176 (35%), Gaps = 14/176 (7%)

Query: 129 PTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPA 188
           PT      +TP   + T   +         A        P+  K  SPT    PA  +  
Sbjct: 335 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 394

Query: 189 SSPLTRSTP-PVRGRAGPSGRAAASPPTPIRSVLA----PQPSTSNSQRLPRPQGAA--- 240
           S+P T   P P   ++ P+     SP T           P P+T        P+  A   
Sbjct: 395 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 454

Query: 241 ----AKSSSQLPIPSAIPRPASRMPL-TSRSVPPGRGALPPDSLS-TRKGLPRPST 290
               A ++++ P P+    PA   P  T+ + P       P+ L+ T    P P+T
Sbjct: 455 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/302 (20%), Positives = 105/302 (34%), Gaps = 29/302 (9%)

Query: 35  LVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQ 94
           + TP+    +     + P      P   R SL P S    E  L        + ++    
Sbjct: 140 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 199

Query: 95  DRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRK 154
           +++++ +G    + K +  +ET  ++ +  +DL PT   L + TP   + T         
Sbjct: 200 NKQTSTDG----KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT----KGPAL 251

Query: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSP---LTRSTPPVRGRAGPSGRAAA 211
            + +    T+ K P++   + PT     ++ +    P    T+S P       P+     
Sbjct: 252 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 311

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGR 271
           +P TP      P P+T+       P     KS+   P   A   P    P T +   P  
Sbjct: 312 APTTP----KEPAPTTTK-----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP-- 360

Query: 272 GALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPG 330
              P +   T    P P+T     +E     P       P   A  +  +P P     P 
Sbjct: 361 -TTPKEPTPTTPKEPAPTT-----KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414

Query: 331 PT 332
           PT
Sbjct: 415 PT 416



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 54/266 (20%), Positives = 95/266 (35%), Gaps = 27/266 (10%)

Query: 37  TPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDR 96
           TP++P        +      PAP   +    P +P+KL     E  +LA    +   +  
Sbjct: 495 TPKEPAPTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPTTPE--KLAPTTPE---KPA 548

Query: 97  ESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGS 156
            +  E L P     +P   T    + P           T   P+P++      +  ++ +
Sbjct: 549 PTTPEELAPT----TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604

Query: 157 VRALRATS-----GKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAA 211
               + T+     G  P+ +K  +PT    PA K  A +     T     +  P+     
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAA-------AKSSSQLPIPSAIPRPASRMPLTS 264
           +P TP      P P+T        P+G A       A ++ + P P  +    ++ P ++
Sbjct: 665 APTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 720

Query: 265 RSVPPGRGALPPDSLSTRKGLPRPST 290
            S  P     P ++  T    P P+T
Sbjct: 721 TSDKPA-PTTPKETAPTTPKEPAPTT 745



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 43/177 (24%), Positives = 64/177 (36%), Gaps = 14/177 (7%)

Query: 168 PSNMKRESPTCNLFPASKSPASSPLT---RSTPPVRGRAGPSGRAAASPPTPIR-SVLAP 223
           P+  K+ +PT    PA  +P  +  T   + TP    +  P+     +P TP   +   P
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560

Query: 224 QPSTSNSQRLPRPQG--AAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGA--LPPDSL 279
           +  T  +   P P    AAA ++ + P P+    PA   P       P   A   P  + 
Sbjct: 561 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620

Query: 280 STRKGLPRPST----AGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPGPT 332
            T    P P+T    A   +  +  K P S   + P    T      P     P PT
Sbjct: 621 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP--APTTPKGTAPTTPKEPAPT 675



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 47/228 (20%), Positives = 75/228 (32%), Gaps = 22/228 (9%)

Query: 110 PSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPS 169
           P     T   + +P     P   +     P+ +   P         + +    T+ K P+
Sbjct: 300 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 359

Query: 170 --NMKRESPTCNLFPA--SKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP 225
               K  +PT    PA  +K PA +      P    +  P+     +P TP      P P
Sbjct: 360 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAP 415

Query: 226 STSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGL 285
           +T+       P+  A  ++   P  +  P P      T++S P      P +   T    
Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT-----TTKSAP----TTPKEPSPTTTKE 466

Query: 286 PRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPGPT 332
           P P+T     +E     P       P   A  +  +P P     P PT
Sbjct: 467 PAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 510



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 46/203 (22%), Positives = 70/203 (34%), Gaps = 35/203 (17%)

Query: 135 TRSTPSPSSLTPRLRSNDRKGSVRALRATS--GKRPSNMKRESPTCNLFPASKSP-ASSP 191
           T   P+P  L P         +      T+  G  P+  K  +PT    PA  +P  ++P
Sbjct: 631 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690

Query: 192 LTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP-----STSNSQRLPRPQGAAAKSSSQ 246
            T   P           A  +P  P    LAP       ST++ +  P      A ++ +
Sbjct: 691 TTLKEP-----------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 739

Query: 247 LPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQ 306
            P P+   +PA   P T  + PP         +ST      P+T         HK P   
Sbjct: 740 EPAPTTPKKPA---PTTPETPPP-----TTSEVSTPTTTKEPTTI--------HKSPDES 783

Query: 307 RLNLPVMGATRSNLQPPRKVAVP 329
              L      ++    P++  VP
Sbjct: 784 TPELSAEPTPKALENSPKEPGVP 806



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/176 (23%), Positives = 62/176 (35%), Gaps = 14/176 (7%)

Query: 129 PTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPA 188
           PT      +TP   + T   +         A        P+  K  SPT    PA  +  
Sbjct: 376 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 435

Query: 189 SSPLTRSTP-PVRGRAGPSGRAAASPPTPIRSVLA----PQPSTSNSQRLPRPQGAA--- 240
           S+P T   P P   ++ P+     SP T           P P+T        P+  A   
Sbjct: 436 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 495

Query: 241 ----AKSSSQLPIPSAIPRPASRMPL-TSRSVPPGRGALPPDSLS-TRKGLPRPST 290
               A ++++ P P+    PA   P  T+ + P       P+ L+ T    P P+T
Sbjct: 496 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/302 (20%), Positives = 105/302 (34%), Gaps = 29/302 (9%)

Query: 35  LVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQ 94
           + TP+    +     + P      P   R SL P S    E  L        + ++    
Sbjct: 192 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 251

Query: 95  DRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRK 154
           +++++ +G    + K +  +ET  ++ +  +DL PT   L + TP   + T         
Sbjct: 252 NKQTSTDG----KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT----KGPAL 303

Query: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSP---LTRSTPPVRGRAGPSGRAAA 211
            + +    T+ K P++   + PT     ++ +    P    T+S P       P+     
Sbjct: 304 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 363

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGR 271
           +P TP      P P+T+       P     KS+   P   A   P    P T +   P  
Sbjct: 364 APTTP----KEPAPTTTK-----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP-- 412

Query: 272 GALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPG 330
              P +   T    P P+T     +E     P       P   A  +  +P P     P 
Sbjct: 413 -TTPKEPTPTTPKEPAPTT-----KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466

Query: 331 PT 332
           PT
Sbjct: 467 PT 468



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 54/266 (20%), Positives = 95/266 (35%), Gaps = 27/266 (10%)

Query: 37  TPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDR 96
           TP++P        +      PAP   +    P +P+KL     E  +LA    +   +  
Sbjct: 547 TPKEPAPTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPTTPE--KLAPTTPE---KPA 600

Query: 97  ESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGS 156
            +  E L P     +P   T    + P           T   P+P++      +  ++ +
Sbjct: 601 PTTPEELAPT----TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656

Query: 157 VRALRATS-----GKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAA 211
               + T+     G  P+ +K  +PT    PA K  A +     T     +  P+     
Sbjct: 657 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAA-------AKSSSQLPIPSAIPRPASRMPLTS 264
           +P TP      P P+T        P+G A       A ++ + P P  +    ++ P ++
Sbjct: 717 APTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 772

Query: 265 RSVPPGRGALPPDSLSTRKGLPRPST 290
            S  P     P ++  T    P P+T
Sbjct: 773 TSDKPA-PTTPKETAPTTPKEPAPTT 797



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 43/177 (24%), Positives = 64/177 (36%), Gaps = 14/177 (7%)

Query: 168 PSNMKRESPTCNLFPASKSPASSPLT---RSTPPVRGRAGPSGRAAASPPTPIR-SVLAP 223
           P+  K+ +PT    PA  +P  +  T   + TP    +  P+     +P TP   +   P
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612

Query: 224 QPSTSNSQRLPRPQG--AAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGA--LPPDSL 279
           +  T  +   P P    AAA ++ + P P+    PA   P       P   A   P  + 
Sbjct: 613 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672

Query: 280 STRKGLPRPST----AGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPGPT 332
            T    P P+T    A   +  +  K P S   + P    T      P     P PT
Sbjct: 673 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP--APTTPKGTAPTTPKEPAPT 727



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 47/228 (20%), Positives = 75/228 (32%), Gaps = 22/228 (9%)

Query: 110 PSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPS 169
           P     T   + +P     P   +     P+ +   P         + +    T+ K P+
Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411

Query: 170 --NMKRESPTCNLFPA--SKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP 225
               K  +PT    PA  +K PA +      P    +  P+     +P TP      P P
Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAP 467

Query: 226 STSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGL 285
           +T+       P+  A  ++   P  +  P P      T++S P      P +   T    
Sbjct: 468 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT-----TTKSAP----TTPKEPSPTTTKE 518

Query: 286 PRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPGPT 332
           P P+T     +E     P       P   A  +  +P P     P PT
Sbjct: 519 PAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 562



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 46/203 (22%), Positives = 70/203 (34%), Gaps = 35/203 (17%)

Query: 135 TRSTPSPSSLTPRLRSNDRKGSVRALRATS--GKRPSNMKRESPTCNLFPASKSP-ASSP 191
           T   P+P  L P         +      T+  G  P+  K  +PT    PA  +P  ++P
Sbjct: 683 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 742

Query: 192 LTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP-----STSNSQRLPRPQGAAAKSSSQ 246
            T   P           A  +P  P    LAP       ST++ +  P      A ++ +
Sbjct: 743 TTLKEP-----------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 791

Query: 247 LPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQ 306
            P P+   +PA   P T  + PP         +ST      P+T         HK P   
Sbjct: 792 EPAPTTPKKPA---PTTPETPPP-----TTSEVSTPTTTKEPTTI--------HKSPDES 835

Query: 307 RLNLPVMGATRSNLQPPRKVAVP 329
              L      ++    P++  VP
Sbjct: 836 TPELSAEPTPKALENSPKEPGVP 858



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/176 (23%), Positives = 62/176 (35%), Gaps = 14/176 (7%)

Query: 129 PTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPA 188
           PT      +TP   + T   +         A        P+  K  SPT    PA  +  
Sbjct: 428 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 487

Query: 189 SSPLTRSTP-PVRGRAGPSGRAAASPPTPIRSVLA----PQPSTSNSQRLPRPQGAA--- 240
           S+P T   P P   ++ P+     SP T           P P+T        P+  A   
Sbjct: 488 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547

Query: 241 ----AKSSSQLPIPSAIPRPASRMPL-TSRSVPPGRGALPPDSLS-TRKGLPRPST 290
               A ++++ P P+    PA   P  T+ + P       P+ L+ T    P P+T
Sbjct: 548 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/302 (20%), Positives = 105/302 (34%), Gaps = 29/302 (9%)

Query: 35  LVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQ 94
           + TP+    +     + P      P   R SL P S    E  L        + ++    
Sbjct: 233 VTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTT 292

Query: 95  DRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRK 154
           +++++ +G    + K +  +ET  ++ +  +DL PT   L + TP   + T         
Sbjct: 293 NKQTSTDG----KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT----KGPAL 344

Query: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSP---LTRSTPPVRGRAGPSGRAAA 211
            + +    T+ K P++   + PT     ++ +    P    T+S P       P+     
Sbjct: 345 TTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP 404

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGR 271
           +P TP      P P+T+       P     KS+   P   A   P    P T +   P  
Sbjct: 405 APTTP----KEPAPTTTK-----EPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP-- 453

Query: 272 GALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPG 330
              P +   T    P P+T     +E     P       P   A  +  +P P     P 
Sbjct: 454 -TTPKEPTPTTPKEPAPTT-----KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507

Query: 331 PT 332
           PT
Sbjct: 508 PT 509



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 54/266 (20%), Positives = 95/266 (35%), Gaps = 27/266 (10%)

Query: 37  TPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDR 96
           TP++P        +      PAP   +    P +P+KL     E  +LA    +   +  
Sbjct: 588 TPKEPAPTTTKKPAPTTPKEPAPTTPK-ETAPTTPKKLTPTTPE--KLAPTTPE---KPA 641

Query: 97  ESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGS 156
            +  E L P     +P   T    + P           T   P+P++      +  ++ +
Sbjct: 642 PTTPEELAPT----TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697

Query: 157 VRALRATS-----GKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAA 211
               + T+     G  P+ +K  +PT    PA K  A +     T     +  P+     
Sbjct: 698 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757

Query: 212 SPPTPIRSVLAPQPSTSNSQRLPRPQGAA-------AKSSSQLPIPSAIPRPASRMPLTS 264
           +P TP      P P+T        P+G A       A ++ + P P  +    ++ P ++
Sbjct: 758 APTTP----KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST 813

Query: 265 RSVPPGRGALPPDSLSTRKGLPRPST 290
            S  P     P ++  T    P P+T
Sbjct: 814 TSDKPA-PTTPKETAPTTPKEPAPTT 838



 Score = 35.4 bits (80), Expect = 0.072
 Identities = 43/177 (24%), Positives = 64/177 (36%), Gaps = 14/177 (7%)

Query: 168 PSNMKRESPTCNLFPASKSPASSPLT---RSTPPVRGRAGPSGRAAASPPTPIR-SVLAP 223
           P+  K+ +PT    PA  +P  +  T   + TP    +  P+     +P TP   +   P
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653

Query: 224 QPSTSNSQRLPRPQG--AAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGA--LPPDSL 279
           +  T  +   P P    AAA ++ + P P+    PA   P       P   A   P  + 
Sbjct: 654 EEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713

Query: 280 STRKGLPRPST----AGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPGPT 332
            T    P P+T    A   +  +  K P S   + P    T      P     P PT
Sbjct: 714 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP--APTTPKGTAPTTPKEPAPT 768



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 47/228 (20%), Positives = 75/228 (32%), Gaps = 22/228 (9%)

Query: 110 PSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPS 169
           P     T   + +P     P   +     P+ +   P         + +    T+ K P+
Sbjct: 393 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452

Query: 170 --NMKRESPTCNLFPA--SKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP 225
               K  +PT    PA  +K PA +      P    +  P+     +P TP      P P
Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP----KEPAP 508

Query: 226 STSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGL 285
           +T+       P+  A  ++   P  +  P P      T++S P      P +   T    
Sbjct: 509 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT-----TTKSAP----TTPKEPSPTTTKE 559

Query: 286 PRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQP-PRKVAVPGPT 332
           P P+T     +E     P       P   A  +  +P P     P PT
Sbjct: 560 PAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPT 603



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 46/203 (22%), Positives = 70/203 (34%), Gaps = 35/203 (17%)

Query: 135 TRSTPSPSSLTPRLRSNDRKGSVRALRATS--GKRPSNMKRESPTCNLFPASKSP-ASSP 191
           T   P+P  L P         +      T+  G  P+  K  +PT    PA  +P  ++P
Sbjct: 724 TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 783

Query: 192 LTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQP-----STSNSQRLPRPQGAAAKSSSQ 246
            T   P           A  +P  P    LAP       ST++ +  P      A ++ +
Sbjct: 784 TTLKEP-----------APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPK 832

Query: 247 LPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQ 306
            P P+   +PA   P T  + PP         +ST      P+T         HK P   
Sbjct: 833 EPAPTTPKKPA---PTTPETPPP-----TTSEVSTPTTTKEPTTI--------HKSPDES 876

Query: 307 RLNLPVMGATRSNLQPPRKVAVP 329
              L      ++    P++  VP
Sbjct: 877 TPELSAEPTPKALENSPKEPGVP 899



 Score = 34.3 bits (77), Expect = 0.16
 Identities = 41/176 (23%), Positives = 62/176 (35%), Gaps = 14/176 (7%)

Query: 129 PTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPA 188
           PT      +TP   + T   +         A        P+  K  SPT    PA  +  
Sbjct: 469 PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTK 528

Query: 189 SSPLTRSTP-PVRGRAGPSGRAAASPPTPIRSVLA----PQPSTSNSQRLPRPQGAA--- 240
           S+P T   P P   ++ P+     SP T           P P+T        P+  A   
Sbjct: 529 SAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588

Query: 241 ----AKSSSQLPIPSAIPRPASRMPL-TSRSVPPGRGALPPDSLS-TRKGLPRPST 290
               A ++++ P P+    PA   P  T+ + P       P+ L+ T    P P+T
Sbjct: 589 PKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644


>gi|239741585 PREDICTED: hypothetical protein XP_002342243 [Homo
           sapiens]
          Length = 439

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 83/311 (26%), Positives = 113/311 (36%), Gaps = 51/311 (16%)

Query: 43  RRGLSHRSDPNAVAPAPQG------VRLSLGPL-SPEKLEEILDEANRLAAQLEQCALQD 95
           R GL+H   P  +AP P         R    P+ SPE       E   ++A   +CA+  
Sbjct: 54  REGLAH--PPQGLAPPPTAGNRPHPTRKCTFPVPSPELGAGREGEVAGVSACGRRCAVLG 111

Query: 96  RESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKG 155
             +A  G    R  P  R    V  D      L T     RS+P+  S++  L    R+G
Sbjct: 112 VRAAARGQLNSRTAPRDRHRG-VGPDPGRETALGTATLSLRSSPTAGSVSTGLVGKQREG 170

Query: 156 SVRALRAT----SGKR---------PSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGR 202
                RA      G R         P+ + R +P     P S SP      RS PP R +
Sbjct: 171 GNGPWRAPVFRLPGARLRLSSQLPSPTTLPRAAPLTPYRPGSPSPRGHSRLRSRPPTRAQ 230

Query: 203 AGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLP-IPSAIPRPASRMP 261
                R  A+P       L+P P+        RP+G   +S   L   P   P    R+P
Sbjct: 231 L----RVGANP-------LSPVPARLRGCHSVRPEGGGVRSCRTLGCCPPTSPHQPPRLP 279

Query: 262 LTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQ 321
           +T     P   ALP  SL +     RP+ AG   R S       Q      +   + +  
Sbjct: 280 VTP---VPQSVALP--SLQS----ARPAAAGAAPRLS------PQAARCTALSTEKPDRP 324

Query: 322 -PPRKVAVPGP 331
            PPR+   P P
Sbjct: 325 GPPRRPPAPTP 335


>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
            sapiens]
          Length = 1309

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 70/267 (26%), Positives = 107/267 (40%), Gaps = 44/267 (16%)

Query: 66   LGPLSPEKLEEILDEANRLAAQ---LEQCALQ---DRESAGEGLGPRRVKPSPRRETFVL 119
            LG +  + +E +L   N+++ +   LE  +++    R++  +G   RR K S RRET   
Sbjct: 1012 LGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMARRSKRSRRRETQDR 1071

Query: 120  KDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCN 179
            + S  + +    + L  S    S L   L S++                      SPT +
Sbjct: 1072 RKSLFKKISKQTSVLHTSRSFSSGLHHSLSSSESLPG------------------SPTHS 1113

Query: 180  LFPASKSPASSPL------TRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRL 233
            L P+  +P  SP       T ++PP    A PS  + ASP     +  +     +     
Sbjct: 1114 LSPSPTTPCRSPAPDVPADTTASPP---SASPSSSSPASPAAAGHTRPSSLHGLAAKLGP 1170

Query: 234  PRPQGAAAKSSSQL-PIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPR----- 287
            PRP+    KS+S + P P A P P S  P  S S  PG    P  S   R+G        
Sbjct: 1171 PRPKTGRRKSTSSIPPSPLACP-PISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGT 1229

Query: 288  ----PSTAGHRVRESGHKVPVSQRLNL 310
                   AG R R    ++ V +RL+L
Sbjct: 1230 GERLDGEAGRRTRGPEAELVVMRRLHL 1256



 Score = 29.3 bits (64), Expect = 5.1
 Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 1/92 (1%)

Query: 239  AAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRES 298
            ++++S    P  S  P P +     +  VP    A PP +  +      P+ AGH    S
Sbjct: 1101 SSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSS 1160

Query: 299  GHKVPVSQRLNLPVMGATRSNLQ-PPRKVAVP 329
             H +        P  G  +S    PP  +A P
Sbjct: 1161 LHGLAAKLGPPRPKTGRRKSTSSIPPSPLACP 1192


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 51/175 (29%), Positives = 70/175 (40%), Gaps = 21/175 (12%)

Query: 128 LPTVNSLTRSTPSPSSLTPRLRSN-DRKGSVRALRATSGKRPSNMKRESPTCNLF----P 182
           LP V  L ++  + SS     R N +   SV  L   +   P +     PT +      P
Sbjct: 126 LPNVTFLPQNATTISS-----RENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPP 180

Query: 183 ASKSPASSPLTRSTPPVRGRAGPSGRA----AASPPTPIRSVLAP-----QPSTSNSQRL 233
           +S +P  +     TP    +A PS  A     A+PPTP  +  AP      P T+ +   
Sbjct: 181 SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPT 240

Query: 234 PRPQGAAAKSSSQLPIPSAIPRPASRMPL--TSRSVPPGRGALPPDSLSTRKGLP 286
           P     A  SSS  P  +A+P   S   L  +S S PP   A PP   +T    P
Sbjct: 241 PSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 6/145 (4%)

Query: 123 PVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLF- 181
           P     P   S T   P  SS  P   +             S   P       PT +   
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT 245

Query: 182 PASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAA 241
           PA  S ++ P T + PP          +A++PP    +   P  +T      P PQ   A
Sbjct: 246 PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTA 305

Query: 242 KSSSQLPIPSAIPRPASRMPLTSRS 266
                 PI +    P +  P TS +
Sbjct: 306 -----APITTPNSSPTTLAPDTSET 325



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 5/103 (4%)

Query: 135 TRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTR 194
           T + P+PS+ TP   S+       A+  T    PS    +  + +  P + +   +P + 
Sbjct: 235 TAAPPTPSATTPAPLSSSAPPETTAVPPT----PSATTLDPSSASAPPETTAAPPTP-SA 289

Query: 195 STPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQ 237
           +TP       P    AA   TP  S     P TS +   P  Q
Sbjct: 290 TTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQ 332


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 51/175 (29%), Positives = 70/175 (40%), Gaps = 21/175 (12%)

Query: 128 LPTVNSLTRSTPSPSSLTPRLRSN-DRKGSVRALRATSGKRPSNMKRESPTCNLF----P 182
           LP V  L ++  + SS     R N +   SV  L   +   P +     PT +      P
Sbjct: 126 LPNVTFLPQNATTISS-----RENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPP 180

Query: 183 ASKSPASSPLTRSTPPVRGRAGPSGRA----AASPPTPIRSVLAP-----QPSTSNSQRL 233
           +S +P  +     TP    +A PS  A     A+PPTP  +  AP      P T+ +   
Sbjct: 181 SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPT 240

Query: 234 PRPQGAAAKSSSQLPIPSAIPRPASRMPL--TSRSVPPGRGALPPDSLSTRKGLP 286
           P     A  SSS  P  +A+P   S   L  +S S PP   A PP   +T    P
Sbjct: 241 PSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 6/145 (4%)

Query: 123 PVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLF- 181
           P     P   S T   P  SS  P   +             S   P       PT +   
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT 245

Query: 182 PASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAA 241
           PA  S ++ P T + PP          +A++PP    +   P  +T      P PQ   A
Sbjct: 246 PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTA 305

Query: 242 KSSSQLPIPSAIPRPASRMPLTSRS 266
                 PI +    P +  P TS +
Sbjct: 306 -----APITTPNSSPTTLAPDTSET 325



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 5/103 (4%)

Query: 135 TRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTR 194
           T + P+PS+ TP   S+       A+  T    PS    +  + +  P + +   +P + 
Sbjct: 235 TAAPPTPSATTPAPLSSSAPPETTAVPPT----PSATTLDPSSASAPPETTAAPPTP-SA 289

Query: 195 STPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQ 237
           +TP       P    AA   TP  S     P TS +   P  Q
Sbjct: 290 TTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQ 332


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 51/175 (29%), Positives = 70/175 (40%), Gaps = 21/175 (12%)

Query: 128 LPTVNSLTRSTPSPSSLTPRLRSN-DRKGSVRALRATSGKRPSNMKRESPTCNLF----P 182
           LP V  L ++  + SS     R N +   SV  L   +   P +     PT +      P
Sbjct: 126 LPNVTFLPQNATTISS-----RENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPP 180

Query: 183 ASKSPASSPLTRSTPPVRGRAGPSGRA----AASPPTPIRSVLAP-----QPSTSNSQRL 233
           +S +P  +     TP    +A PS  A     A+PPTP  +  AP      P T+ +   
Sbjct: 181 SSSAPPETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPT 240

Query: 234 PRPQGAAAKSSSQLPIPSAIPRPASRMPL--TSRSVPPGRGALPPDSLSTRKGLP 286
           P     A  SSS  P  +A+P   S   L  +S S PP   A PP   +T    P
Sbjct: 241 PSATTPAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPP 295



 Score = 35.0 bits (79), Expect = 0.093
 Identities = 34/145 (23%), Positives = 47/145 (32%), Gaps = 6/145 (4%)

Query: 123 PVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLF- 181
           P     P   S T   P  SS  P   +             S   P       PT +   
Sbjct: 186 PETTAAPPTPSATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATT 245

Query: 182 PASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAA 241
           PA  S ++ P T + PP          +A++PP    +   P  +T      P PQ   A
Sbjct: 246 PAPLSSSAPPETTAVPPTPSATTLDPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTA 305

Query: 242 KSSSQLPIPSAIPRPASRMPLTSRS 266
                 PI +    P +  P TS +
Sbjct: 306 -----APITTPNSSPTTLAPDTSET 325



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 26/103 (25%), Positives = 40/103 (38%), Gaps = 5/103 (4%)

Query: 135 TRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTR 194
           T + P+PS+ TP   S+       A+  T    PS    +  + +  P + +   +P + 
Sbjct: 235 TAAPPTPSATTPAPLSSSAPPETTAVPPT----PSATTLDPSSASAPPETTAAPPTP-SA 289

Query: 195 STPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQ 237
           +TP       P    AA   TP  S     P TS +   P  Q
Sbjct: 290 TTPAPPSSPAPQETTAAPITTPNSSPTTLAPDTSETSAAPTHQ 332


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 51/195 (26%), Positives = 76/195 (38%), Gaps = 27/195 (13%)

Query: 105  PRRVKP-SPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRAT 163
            P  V P SP+  T   K++P     P+V +L      P++  P+           AL  T
Sbjct: 867  PSAVTPLSPKGVTLPPKETPT----PSVVNLPFPKEGPATPAPK--------QAPALSMT 914

Query: 164  SGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRA--------AASPPT 215
            S        R +P     PAS SP  +P   +  P   + GP+  +        AA+PP+
Sbjct: 915  SSS--PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972

Query: 216  PIRSVLAPQPS---TSNSQRLPRPQGAAAKSSSQ-LPIPSAIPRPASRMPLTSRSVPPGR 271
            P      P P    T  +   P P+G  A  S +  P P A+  P+ +    +   P G 
Sbjct: 973  PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGA 1032

Query: 272  GALPPDSLSTRKGLP 286
               P  +  + KG P
Sbjct: 1033 STPPAATPPSPKGSP 1047



 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 50/182 (27%), Positives = 75/182 (41%), Gaps = 20/182 (10%)

Query: 120  KDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMK-----RE 174
            KDSP     PT  S  +  P+PS++TP       KG     + T      N+        
Sbjct: 847  KDSPATTHSPTPPS-PKGAPTPSAVTPL----SPKGVTLPPKETPTPSVVNLPFPKEGPA 901

Query: 175  SPTCNLFPASKSPASSPL-TRSTPPVRG-RAGPSGRAAASPPTPIRSVLAPQPSTSNSQR 232
            +P     PA    +SSP   R+TP  +G  A PS + A +PP          P+T + + 
Sbjct: 902  TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961

Query: 233  LPRPQGA---AAKSSSQLPIPSAIPRPASRMPLTSR---SVPPGRGALPPDSLS--TRKG 284
             P P  A   + K     P P   P P +  P + +   + P  +GA  P +++  + KG
Sbjct: 962  APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021

Query: 285  LP 286
             P
Sbjct: 1022 SP 1023



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 53/200 (26%), Positives = 76/200 (38%), Gaps = 21/200 (10%)

Query: 100  GEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRA 159
            G    P    PSP+        +P+    PT  + T  +P     TP L     KG+   
Sbjct: 1031 GASTPPAATPPSPKGSPAA---TPLPKGAPTTPAATLPSPKGGPATPSL-----KGAPTP 1082

Query: 160  LRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRS 219
              AT           SP     P + +P S     +TPP +G   P+   AA+PP+P   
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG--APT-TPAATPPSPKGG 1139

Query: 220  VLAPQPS---TSNSQRLPRPQGAAAKSSSQ-LPIPSAIPRPASRMPLTS---RSVPPGRG 272
            +  P P    T+ +   P P+G  A    +  P   A   P+ +  L +   +  P    
Sbjct: 1140 LATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199

Query: 273  ALPPDSLSTRKGLPRPSTAG 292
            A PP   S + GL  PS  G
Sbjct: 1200 ATPP---SPKGGLATPSPKG 1216



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 49/174 (28%), Positives = 64/174 (36%), Gaps = 35/174 (20%)

Query: 136  RSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASK-SPASSPLTR 194
            +  P+P ++TP       KGS  A     G         +P     P+ K SPA++PL +
Sbjct: 1006 KGAPTPPAVTPP----SPKGSPAATPFPKGA-------STPPAATPPSPKGSPAATPLPK 1054

Query: 195  STP---------PVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSS 245
              P         P  G A PS + A +PP       A  PS       P P+GA    ++
Sbjct: 1055 GAPTTPAATLPSPKGGPATPSLKGAPTPPA------ATPPSPKGGPATPSPKGAPMPPAA 1108

Query: 246  QLPIPS---AIPRPASRMPLTSRSVPP----GRGALPPDSLSTRKGLPRPSTAG 292
              P P    A P P    P T  + PP    G    PP    T      PS  G
Sbjct: 1109 TPPSPKGGLATP-PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 69/276 (25%), Positives = 99/276 (35%), Gaps = 53/276 (19%)

Query: 38   PEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDRE 97
            P  P  +G    + P A  P+P+G     GP +P      +  A        +  L    
Sbjct: 1071 PATPSLKGAP--TPPAATPPSPKG-----GPATPSPKGAPMPPA--ATPPSPKGGLATPP 1121

Query: 98   SAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSV 157
              G    P    PSP+        +P     PT  + T  +P     TP       KG+ 
Sbjct: 1122 HKGAPTTPAATPPSPKGGLA----TPPPKGAPTTPAATPPSPKGGLATP-----PPKGAP 1172

Query: 158  RALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAA-----AS 212
                AT       +   SP      A  +PA++P +    P  G A PS + A     A+
Sbjct: 1173 TTPAATPPSPKGGLATPSPK----GAPTTPAATPPS----PKGGLATPSPKGAPTTPAAT 1224

Query: 213  PPTPIRSVLAPQPS---TSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSR---S 266
            PP+P   +  P P    T+ +   P P+G  A      P P   P P +  P + +   +
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPA-----TPPPKGAPTPPAATPPSLKGGLA 1279

Query: 267  VPPGRGA------LPPD-----SLSTRKGLPRPSTA 291
             PP +GA       PP      + S  KG P P  A
Sbjct: 1280 TPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 43/163 (26%), Positives = 65/163 (39%), Gaps = 42/163 (25%)

Query: 182 PASKSPASSPLTRSTPPVRGRAGPSGRAA--ASPPTPIRSVLAPQ-----------PSTS 228
           P+    + SP T+  P  +G AGP       +SP +P+ +   P+           P+T+
Sbjct: 794 PSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATT 853

Query: 229 NSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRP 288
           +S   P P+GA        P PSA+       PL+ + V      LPP      K  P P
Sbjct: 854 HSPTPPSPKGA--------PTPSAV------TPLSPKGV-----TLPP------KETPTP 888

Query: 289 STAGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVAVPGP 331
           S       + G   P  ++   P +  T S+  P +  A P P
Sbjct: 889 SVVNLPFPKEGPATPAPKQ--APALSMTSSS--PKKARATPAP 927



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 63/264 (23%), Positives = 106/264 (40%), Gaps = 42/264 (15%)

Query: 105  PRRVKPSPRR--ETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRA 162
            P    PSP +   T   K +P    + T +SL  S  SP+S+T ++ +   + S + L A
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPV-TPSSLKDSPTSPASVTCKMGATVPQAS-KGLPA 1674

Query: 163  TSGKRPSNMKR-------ESPTCNLFPASKSPASSPLTRSTPPV-------RGRAGPSGR 208
              G  P+ +K        ES      P  K P +   + ++PP+        G  GP   
Sbjct: 1675 KKG--PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732

Query: 209  AAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSA-----IPRPASRMPLT 263
             A +P  P++   +      ++   P+   A  +S +  P+ +A     +P+P S   ++
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPES-ASVS 1791

Query: 264  SRSVPPGRGALPPDSLST--RKGLPRPSTAGHRVRESGHK--VPVSQRLNLPVM------ 313
            +   PP    L P  + T   K    PS+ G  V ES  K   P  +   LP++      
Sbjct: 1792 AAPSPPVSLPLAPSPVPTLPPKQQFLPSSPG-LVLESPSKPLAPADEDELLPLIPPEPIS 1850

Query: 314  -----GATRSNLQPPRKVAVPGPT 332
                  +   N+  P+   +P PT
Sbjct: 1851 GGVPFQSVLVNMPTPKSAGIPVPT 1874



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 55/218 (25%), Positives = 75/218 (34%), Gaps = 29/218 (13%)

Query: 137  STPSPSSL--TPRLRSNDRKGSVRALRATSGKRPSNMKRESPTCNLF-PASKSPASSPLT 193
            +TPSP     TP       KG +                 SP   L  P+ K   ++P  
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246

Query: 194  RSTPPVRGRAGPSGRAAASPPTPIRSVL-----------APQPSTSNSQRLPRPQGAAAK 242
                P  G A P  + A +PP      L           AP P+       P P+G  A 
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP---PSPKGGPAT 1303

Query: 243  SSSQ-LPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLS--TRKGLP-----RPSTAGHR 294
            S  +  P P A   P+   P  S   PP +GA  P +++  + KG P      PS+ G  
Sbjct: 1304 SPPKGAPTPPAATPPS---PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP 1360

Query: 295  VRESGHKVPVSQRLNLPVMGA-TRSNLQPPRKVAVPGP 331
               S  + P          G    +   P R  A+P P
Sbjct: 1361 TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 58/243 (23%), Positives = 88/243 (36%), Gaps = 32/243 (13%)

Query: 105  PRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATS 164
            P    PSP+    +   +P     PT  S ++  P+P + TP       KG   A+   S
Sbjct: 1336 PAVTPPSPKGTPTLPATTPSSKGGPTTPS-SKEGPTPPAATP-----SHKGGP-AMTPPS 1388

Query: 165  GKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPP--TPIRSVLA 222
             KR   +   SP  +    +  P S     +TP  R  A    +   +PP  TP+    A
Sbjct: 1389 PKRGPAIP--SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKA 1446

Query: 223  PQ-------PSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALP 275
            P        P+T +S+  P        S  + P P  +   +S     +   P G   LP
Sbjct: 1447 PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506

Query: 276  PDSLSTRKGLPRPSTAGHRVRESGHKVPVSQRLNL-----PVMGATRSNLQPPRKVAVPG 330
                S+ K +P           S  + P++    L     P   A +  L PP  + VP 
Sbjct: 1507 AVIPSSPKEVP--------ATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP-AMTVPS 1557

Query: 331  PTR 333
            P +
Sbjct: 1558 PKK 1560



 Score = 36.6 bits (83), Expect = 0.032
 Identities = 42/168 (25%), Positives = 64/168 (38%), Gaps = 29/168 (17%)

Query: 129  PTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRES---------PTCN 179
            PT+ ++  S+P     TP  R +    +   L   S K P+ +  +          P+  
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLL---SKKTPATLAPKEALIPPAMTVPSPK 1559

Query: 180  LFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGA 239
              PA  +P  +P T           PS + A+SPP    S     PS    + L  P   
Sbjct: 1560 KTPAIPTPKEAPAT-----------PSSKEASSPPAVTPSTYKGAPS---PKELLIPPAV 1605

Query: 240  AAKSSSQLPIPSAIPRPA-SRMPLTSRSVPPGRGALPPDSLSTRKGLP 286
             + S  + P P A+  P+  + P T    P G    PP + S+ K  P
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPAT--PAPKGTPTSPPVTPSSLKDSP 1651


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 48.5 bits (114), Expect = 8e-06
 Identities = 45/165 (27%), Positives = 60/165 (36%), Gaps = 17/165 (10%)

Query: 129 PTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKRE----SPTCNLFPAS 184
           P   S T    S S+  P             L   S K P+  + +    +P   L P  
Sbjct: 162 PNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGR 221

Query: 185 KSPASSPLTRSTP-PVRGRAGPSGRAAASPPTPIRSVLA-----PQPSTSNSQRLP---- 234
           + P + P  +  P PV  R GPSG++ A PP P R           P+  ++  LP    
Sbjct: 222 EGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHN 281

Query: 235 ---RPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPPGRGALPP 276
              R      +  +  P  SA P   S  P      PP RGA PP
Sbjct: 282 SLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPP 326



 Score = 37.7 bits (86), Expect = 0.014
 Identities = 61/239 (25%), Positives = 81/239 (33%), Gaps = 26/239 (10%)

Query: 35  LVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQ 94
           L  P      G+ H S  +A  P P G R +  P +P  +      A      L     Q
Sbjct: 159 LSRPNTTSSTGMKHSS--SAPPPPPPGRRANAPP-TPLPMHSSKAPAYNREKPLPPTPGQ 215

Query: 95  DRESAGEGL-GPRRVKPSPRRETFVLKDSPVRDLL-PTVNSLTRSTPSPSSLTPRLRSND 152
                 EG   P  VKP P         SPV     P+  SL  + P P    P    N 
Sbjct: 216 RLHPGREGPPAPPPVKPPP---------SPVNIRTGPSGQSL--APPPPPYRQPPGVPNG 264

Query: 153 RKGSVRALRATSGKRPSNMKRESP--TCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAA 210
                        +R +++ R++P     L P   + AS  L  + PP   R  PS  AA
Sbjct: 265 PSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAA 324

Query: 211 ASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
             PP P+          + ++  P P        S+ P     P P SR P      PP
Sbjct: 325 PPPPPPV--------IRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRTPAGPPPPPP 375



 Score = 30.4 bits (67), Expect = 2.3
 Identities = 48/185 (25%), Positives = 70/185 (37%), Gaps = 27/185 (14%)

Query: 162 ATSGKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPI--RS 219
           A SG+   +      +    P  + P+   L+R  P      G    ++A PP P   R+
Sbjct: 129 AASGRPQDDTDSSRASLPELPRMQRPSLPDLSR--PNTTSSTGMKHSSSAPPPPPPGRRA 186

Query: 220 VLAPQPSTSNSQRLP---RPQGAAAKSSSQL-------PIPSAIPRPASRMPLTSRSVPP 269
              P P   +S + P   R +        +L       P P  +  P S  P+  R+ P 
Sbjct: 187 NAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPS--PVNIRTGPS 244

Query: 270 GRG-ALPPDSLSTRKGLPR-PSTAGHRVRESGHKVPVSQRLNLPVMGATRSNLQPPRKVA 327
           G+  A PP       G+P  PS+      ES  ++P  QR N       R    P R +A
Sbjct: 245 GQSLAPPPPPYRQPPGVPNGPSSP---TNESAPELP--QRHN----SLHRKTPGPVRGLA 295

Query: 328 VPGPT 332
            P PT
Sbjct: 296 PPPPT 300


>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
           sapiens]
          Length = 1038

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 42/133 (31%), Positives = 57/133 (42%), Gaps = 16/133 (12%)

Query: 165 GKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQ 224
           GK PS+ +    T  +F A +      L    P       PS      P  P R  + P+
Sbjct: 695 GKPPSSAQ----TAEIFQALQQECMRQL--QAPAGSPAPSPSPGGDDKPQVPPRVPIPPR 748

Query: 225 PSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLT-------SRSVPPGRGALPPD 277
           P+  + Q  P P G   + +SQ P P++ PR   R PL+       S  VPPG   LPP 
Sbjct: 749 PTRPHVQLSPAPPGE--EETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPP- 805

Query: 278 SLSTRKGLPRPST 290
            LS+  G   P+T
Sbjct: 806 RLSSSPGKTMPTT 818


>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
           sapiens]
          Length = 1086

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 42/133 (31%), Positives = 57/133 (42%), Gaps = 16/133 (12%)

Query: 165 GKRPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQ 224
           GK PS+ +    T  +F A +      L    P       PS      P  P R  + P+
Sbjct: 773 GKPPSSAQ----TAEIFQALQQECMRQL--QAPAGSPAPSPSPGGDDKPQVPPRVPIPPR 826

Query: 225 PSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLT-------SRSVPPGRGALPPD 277
           P+  + Q  P P G   + +SQ P P++ PR   R PL+       S  VPPG   LPP 
Sbjct: 827 PTRPHVQLSPAPPGE--EETSQWPGPASPPRVPPREPLSPQGSRTPSPLVPPGSSPLPP- 883

Query: 278 SLSTRKGLPRPST 290
            LS+  G   P+T
Sbjct: 884 RLSSSPGKTMPTT 896


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 76/289 (26%), Positives = 111/289 (38%), Gaps = 60/289 (20%)

Query: 89  EQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDL-LPTVNSLTRSTPSPSSLTPR 147
           +QC   D   +   LGP   + S R  TF        DL L  + +LT +TP+  SL   
Sbjct: 234 KQCGQADTYQSP--LGPLFSQDSGRPFTFQ------SDLALLGLENLTTATPALGSLPA- 284

Query: 148 LRSNDRKGSVRALRATSGKRPS------NMKRESPTCNLFPASKSPASSPLTRSTPPVRG 201
                 +G+V     T  +R S      +M    P       +K  AS+ L    P   G
Sbjct: 285 --GRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVG 342

Query: 202 RAGPSGRAAASPP------TPIRSVLAPQPSTSNSQ----RLPRPQGAAAKSS------- 244
            +  + R AA+ P      T I   L  +PS  ++     + P P    A SS       
Sbjct: 343 GSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALP 402

Query: 245 -------SQLPIPSAIPRPAS----RMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGH 293
                  +  P+P+ + RPA     R P   R  PP    LPP + S++K +P  +    
Sbjct: 403 TQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEA 462

Query: 294 RV----------RESGHKVPVSQRLN---LPVMGATRSNLQPPRKVAVP 329
           ++          R S HK P    L+    P  G+TRS  +PP  +  P
Sbjct: 463 KITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRST-RPPATMVPP 510



 Score = 36.2 bits (82), Expect = 0.042
 Identities = 70/323 (21%), Positives = 106/323 (32%), Gaps = 44/323 (13%)

Query: 37  TPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDEANRLAAQLEQCALQDR 96
           TP KP R   ++     AV    Q       PL P KL      +N L   L        
Sbjct: 296 TPTKPQRTSPTNPHQHMAVGGPAQT------PLLPAKLSA----SNALDPMLPASV---- 341

Query: 97  ESAGEGLGPRRVKPSPRRE---TFVLKDSPVRDLLPTVNSLTRSTPSPSSLT-PRLRSND 152
              G    PR     P ++   T + K  P +   P+ + +   +P P+  T P   +  
Sbjct: 342 --GGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKS 399

Query: 153 RKGSVRALRATSGKRPSNMKRES---------------PTCNLFPASKSPASSP---LTR 194
              + + +  TS   P+ + R +               P+    P + S +  P   L R
Sbjct: 400 ALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLAR 459

Query: 195 STPPVRGRAGPSGRAAAS-----PPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPI 249
           +   +   A     A  S     P T + S  AP P ++ S R P         +S    
Sbjct: 460 TEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRT 519

Query: 250 PSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLP-RPSTAGHRVRESGHKVPVSQRL 308
             A+P P S    + + +            S RK +P RP  A   V  S      S R 
Sbjct: 520 APAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQ 579

Query: 309 NLPVMGATRSNLQPPRKVAVPGP 331
             P    T + +  P +     P
Sbjct: 580 PQPSQQTTPALVLAPAQFLSSSP 602


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 59/254 (23%), Positives = 96/254 (37%), Gaps = 40/254 (15%)

Query: 70  SPEKLEEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLP 129
           S  K+ E+  + ++   +LE   L++R S    +G  R  P P +       +P R    
Sbjct: 422 SMAKIAELEKQLSQARKELE--TLRERFSESTAMGASRRPPEPEKAP---PAAPTR---- 472

Query: 130 TVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGKRPSNMKR---ESPTCNLFPASKS 186
                      PS+L  ++   + KG +R LR         +      +P+    P    
Sbjct: 473 -----------PSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGV 521

Query: 187 PASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQ 246
           P  SP    +P +   A P+  AA  PP P+  + +PQ +  ++     P   + +    
Sbjct: 522 PTGSP----SPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPA 577

Query: 247 LPIPSAIPRPASRMPL---TSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESG---- 299
            P+P  +P P    P    T   VPP     PP       G P P   G R  E G    
Sbjct: 578 PPLPGDLPPPPPPPPPPPGTDGPVPP-----PPPPPPPPPGGP-PDALGRRDSELGPGVK 631

Query: 300 HKVPVSQRLNLPVM 313
            K P+  +  +P++
Sbjct: 632 AKKPIQTKFRMPLL 645


>gi|223633988 hypothetical protein LOC85379 [Homo sapiens]
          Length = 1806

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 76/274 (27%), Positives = 105/274 (38%), Gaps = 63/274 (22%)

Query: 21  LSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDE 80
           L+P    +E+D+    +P   LR        P++  P+P G       LS E   + LD 
Sbjct: 66  LAPKPFSKEQDVK---SPVPSLR--------PSSTGPSPSG------GLSEEPAAKDLD- 107

Query: 81  ANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPS 140
            NR+   + Q         G G GPR   P   +  F+   S    L  T  S       
Sbjct: 108 -NRMPGLVGQ-------EVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKS------- 152

Query: 141 PSSLTPRLRSNDRKGSVRALRATSGKRPS-NMKRESPTCNLFPASKSPASSPLTRST-PP 198
                P L     +G+  A    SG RP    K   PT    PA   P S+PL++ T PP
Sbjct: 153 ----GPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQK--PAGTLPRSAPLSQDTKPP 206

Query: 199 V----RGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIP 254
           V     G+  P  +A++   T  R ++ P+P      RL R   +A  + S  P      
Sbjct: 207 VPQEEAGQDHPPSKASSVEDT-ARPLVEPRP------RLKRRPVSAIFTESIQP-----Q 254

Query: 255 RPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRP 288
           +P      T   VPP     PP+    RK  PRP
Sbjct: 255 KPGPGAAATVGKVPP----TPPEKTWVRK--PRP 282



 Score = 32.3 bits (72), Expect = 0.61
 Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 17/185 (9%)

Query: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTR---STPPVRGRAG--PSGRA 209
           GS+  L A  G      K E+ T   F  +   + +P  R   +  P+R  A   P  R 
Sbjct: 8   GSITPLTAVPGLGEMG-KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRL 66

Query: 210 AASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
           A  P +  + V +P PS   S   P P G  ++  +   + + +P       L  + V  
Sbjct: 67  APKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMP------GLVGQEVGS 120

Query: 270 GRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP-----VSQRLNLPVMGATRSNLQPPR 324
           G G      L  +    RPS++   + E+    P     VS+      +G + S  +   
Sbjct: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180

Query: 325 KVAVP 329
           K A+P
Sbjct: 181 KPALP 185


>gi|239752069 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 216

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 48/173 (27%), Positives = 74/173 (42%), Gaps = 24/173 (13%)

Query: 122 SPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGK--------RPSNMKR 173
           S  R  LP+V +    T S  ++    RS+ + GS+  LR             RP + + 
Sbjct: 39  SASRPALPSVGAAP--TSSARAVQAASRSSAKPGSIATLRGAPSALLCEWDPPRPCSARA 96

Query: 174 ESPTCNLFPASKSPASS--PLTRS-TPPVRGRAGPSGRAAASPPTPI----RSVLAPQPS 226
            +   +  P ++S A S  PL R  T P RG    S  +    PTP+    R + AP  +
Sbjct: 97  ATAAVSRGPRARSSACSRLPLPRKLTEPERGGGAQSQASQLIRPTPLGTRERPLAAPPGN 156

Query: 227 TSNSQR----LPRPQGAAAKSSSQLPIPSAIPRPASRMPLTS---RSVPPGRG 272
            + S+R     P P GA A  ++  P   + PRP + +   +    S+ PG G
Sbjct: 157 CARSRREGPSRPAPTGARALGAACTPRAPSAPRPTAHLGFVNSGRESLGPGEG 209



 Score = 32.0 bits (71), Expect = 0.79
 Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 13/147 (8%)

Query: 184 SKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKS 243
           S S  + P   + P    RA  +   +++ P  I ++     +       PRP  A A +
Sbjct: 39  SASRPALPSVGAAPTSSARAVQAASRSSAKPGSIATLRGAPSALLCEWDPPRPCSARAAT 98

Query: 244 SSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP 303
           ++    P A     SR+PL  +   P RG     + S    L RP+  G R R       
Sbjct: 99  AAVSRGPRARSSACSRLPLPRKLTEPERGG---GAQSQASQLIRPTPLGTRERP------ 149

Query: 304 VSQRLNLPVMGATRSNLQPPRKVAVPG 330
               L  P     RS  + P + A  G
Sbjct: 150 ----LAAPPGNCARSRREGPSRPAPTG 172


>gi|239747180 PREDICTED: hypothetical protein XP_002343933 [Homo
           sapiens]
          Length = 1595

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 76/274 (27%), Positives = 105/274 (38%), Gaps = 63/274 (22%)

Query: 21  LSPSDSREEEDITVLVTPEKPLRRGLSHRSDPNAVAPAPQGVRLSLGPLSPEKLEEILDE 80
           L+P    +E+D+    +P   LR        P++  P+P G       LS E   + LD 
Sbjct: 66  LAPKPFSKEQDVK---SPVPSLR--------PSSTGPSPSG------GLSEEPAAKDLD- 107

Query: 81  ANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSLTRSTPS 140
            NR+   + Q         G G GPR   P   +  F+   S    L  T  S       
Sbjct: 108 -NRMPGLVGQ-------EVGSGEGPRTSSPLFNKAVFLRPSSSTMILFETTKS------- 152

Query: 141 PSSLTPRLRSNDRKGSVRALRATSGKRPS-NMKRESPTCNLFPASKSPASSPLTRST-PP 198
                P L     +G+  A    SG RP    K   PT    PA   P S+PL++ T PP
Sbjct: 153 ----GPALGKAVSEGAEEAKLGVSGSRPEVAAKPALPTQK--PAGTLPRSAPLSQDTKPP 206

Query: 199 V----RGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIP 254
           V     G+  P  +A++   T  R ++ P+P      RL R   +A  + S  P      
Sbjct: 207 VPQEEAGQDHPPSKASSVEDT-ARPLVEPRP------RLKRRPVSAIFTESIQP-----Q 254

Query: 255 RPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRP 288
           +P      T   VPP     PP+    RK  PRP
Sbjct: 255 KPGPGAAATVGKVPP----TPPEKTWVRK--PRP 282



 Score = 32.3 bits (72), Expect = 0.61
 Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 17/185 (9%)

Query: 155 GSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSPLTR---STPPVRGRAG--PSGRA 209
           GS+  L A  G      K E+ T   F  +   + +P  R   +  P+R  A   P  R 
Sbjct: 8   GSITPLTAVPGLGEMG-KEETLTRTYFLQAGEASGAPPARILEAKSPLRSPARLLPLPRL 66

Query: 210 AASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPSAIPRPASRMPLTSRSVPP 269
           A  P +  + V +P PS   S   P P G  ++  +   + + +P       L  + V  
Sbjct: 67  APKPFSKEQDVKSPVPSLRPSSTGPSPSGGLSEEPAAKDLDNRMP------GLVGQEVGS 120

Query: 270 GRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP-----VSQRLNLPVMGATRSNLQPPR 324
           G G      L  +    RPS++   + E+    P     VS+      +G + S  +   
Sbjct: 121 GEGPRTSSPLFNKAVFLRPSSSTMILFETTKSGPALGKAVSEGAEEAKLGVSGSRPEVAA 180

Query: 325 KVAVP 329
           K A+P
Sbjct: 181 KPALP 185


>gi|239746566 PREDICTED: hypothetical protein XP_002343789 [Homo
           sapiens]
          Length = 216

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 48/173 (27%), Positives = 74/173 (42%), Gaps = 24/173 (13%)

Query: 122 SPVRDLLPTVNSLTRSTPSPSSLTPRLRSNDRKGSVRALRATSGK--------RPSNMKR 173
           S  R  LP+V +    T S  ++    RS+ + GS+  LR             RP + + 
Sbjct: 39  SASRPALPSVGAAP--TSSARAVQAASRSSAKPGSIATLRGAPSALLCEWDPPRPCSARA 96

Query: 174 ESPTCNLFPASKSPASS--PLTRS-TPPVRGRAGPSGRAAASPPTPI----RSVLAPQPS 226
            +   +  P ++S A S  PL R  T P RG    S  +    PTP+    R + AP  +
Sbjct: 97  ATAAVSRGPRARSSACSRLPLPRKLTEPERGGGAQSQASQLIRPTPLGTRERPLAAPPGN 156

Query: 227 TSNSQR----LPRPQGAAAKSSSQLPIPSAIPRPASRMPLTS---RSVPPGRG 272
            + S+R     P P GA A  ++  P   + PRP + +   +    S+ PG G
Sbjct: 157 CARSRREGPSRPAPTGARALGAACTPRAPSAPRPTAHLGFVNSGRESLGPGEG 209



 Score = 32.0 bits (71), Expect = 0.79
 Identities = 36/147 (24%), Positives = 54/147 (36%), Gaps = 13/147 (8%)

Query: 184 SKSPASSPLTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKS 243
           S S  + P   + P    RA  +   +++ P  I ++     +       PRP  A A +
Sbjct: 39  SASRPALPSVGAAPTSSARAVQAASRSSAKPGSIATLRGAPSALLCEWDPPRPCSARAAT 98

Query: 244 SSQLPIPSAIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP 303
           ++    P A     SR+PL  +   P RG     + S    L RP+  G R R       
Sbjct: 99  AAVSRGPRARSSACSRLPLPRKLTEPERGG---GAQSQASQLIRPTPLGTRERP------ 149

Query: 304 VSQRLNLPVMGATRSNLQPPRKVAVPG 330
               L  P     RS  + P + A  G
Sbjct: 150 ----LAAPPGNCARSRREGPSRPAPTG 172


>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
          Length = 1062

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 66/232 (28%), Positives = 90/232 (38%), Gaps = 44/232 (18%)

Query: 75  EEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSL 134
           EE      R  +  E  +L  RE     L P+RV+  PR          VR      +S 
Sbjct: 324 EEKHSAVQRQGSGRESPSLASREGKYIPL-PQRVREGPR--------GGVR-----CSSS 369

Query: 135 TRSTPSPSSLTPR---LRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSP 191
               P  SSL PR      N   G     R  +G  PS M          P ++ P    
Sbjct: 370 RGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG-PSRMS---------PKAQRPLRGA 419

Query: 192 LTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPS 251
            T S+P  R    PSG  +  PP  +  +  P+   S +   P P  A   S  + PI S
Sbjct: 420 KTLSSPSNR----PSGETSVPPPPAVGRMYPPRSPKSAA---PAPISA---SCPEPPIGS 469

Query: 252 AIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP 303
           A+P  ++ +P+TS    PG G++ P S       P+ S A   V+E   K P
Sbjct: 470 AVPTSSASIPVTSSVSDPGVGSISPAS-------PKISLAPTDVKELSTKEP 514



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 9/115 (7%)

Query: 167 RPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAA--SPPTPIRSVLAPQ 224
           +P  +++ S      P  ++ A  P   ++PP  G  GP   +AA   PP      L P 
Sbjct: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62

Query: 225 PSTSNSQRLPRPQGAAAKSSSQLPIPSA-IPRPASRMPLTSRSVPPGRGALPPDS 278
            +  +  R    +GA    + Q P P     RP +    ++R    G+G  PP S
Sbjct: 63  AAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG--PPQS 111


>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
          Length = 1044

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 66/232 (28%), Positives = 90/232 (38%), Gaps = 44/232 (18%)

Query: 75  EEILDEANRLAAQLEQCALQDRESAGEGLGPRRVKPSPRRETFVLKDSPVRDLLPTVNSL 134
           EE      R  +  E  +L  RE     L P+RV+  PR          VR      +S 
Sbjct: 324 EEKHSAVQRQGSGRESPSLASREGKYIPL-PQRVREGPR--------GGVR-----CSSS 369

Query: 135 TRSTPSPSSLTPR---LRSNDRKGSVRALRATSGKRPSNMKRESPTCNLFPASKSPASSP 191
               P  SSL PR      N   G     R  +G  PS M          P ++ P    
Sbjct: 370 RGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG-PSRMS---------PKAQRPLRGA 419

Query: 192 LTRSTPPVRGRAGPSGRAAASPPTPIRSVLAPQPSTSNSQRLPRPQGAAAKSSSQLPIPS 251
            T S+P  R    PSG  +  PP  +  +  P+   S +   P P  A   S  + PI S
Sbjct: 420 KTLSSPSNR----PSGETSVPPPPAVGRMYPPRSPKSAA---PAPISA---SCPEPPIGS 469

Query: 252 AIPRPASRMPLTSRSVPPGRGALPPDSLSTRKGLPRPSTAGHRVRESGHKVP 303
           A+P  ++ +P+TS    PG G++ P S       P+ S A   V+E   K P
Sbjct: 470 AVPTSSASIPVTSSVSDPGVGSISPAS-------PKISLAPTDVKELSTKEP 514



 Score = 29.6 bits (65), Expect = 3.9
 Identities = 30/115 (26%), Positives = 47/115 (40%), Gaps = 9/115 (7%)

Query: 167 RPSNMKRESPTCNLFPASKSPASSPLTRSTPPVRGRAGPSGRAAA--SPPTPIRSVLAPQ 224
           +P  +++ S      P  ++ A  P   ++PP  G  GP   +AA   PP      L P 
Sbjct: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62

Query: 225 PSTSNSQRLPRPQGAAAKSSSQLPIPSA-IPRPASRMPLTSRSVPPGRGALPPDS 278
            +  +  R    +GA    + Q P P     RP +    ++R    G+G  PP S
Sbjct: 63  AAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG--PPQS 111


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.129    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,703,321
Number of Sequences: 37866
Number of extensions: 1078587
Number of successful extensions: 9522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 1237
Number of HSP's that attempted gapping in prelim test: 6299
Number of HSP's gapped (non-prelim): 3382
length of query: 333
length of database: 18,247,518
effective HSP length: 103
effective length of query: 230
effective length of database: 14,347,320
effective search space: 3299883600
effective search space used: 3299883600
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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