Guide to the Human Genome
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Search of human proteins with 73747829

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|73747829 ligase III, DNA, ATP-dependent isoform alpha
precursor [Homo sapiens]
         (1009 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precurs...  2043   0.0  
gi|73747844 ligase III, DNA, ATP-dependent isoform beta precurso...  1885   0.0  
gi|4557719 DNA ligase I [Homo sapiens]                                175   2e-43
gi|46255052 DNA ligase IV [Homo sapiens]                              152   1e-36
gi|23199993 DNA ligase IV [Homo sapiens]                              152   1e-36
gi|148539894 DNA ligase IV [Homo sapiens]                             152   1e-36
gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo...    54   7e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa...    38   0.042
gi|93102361 palladin [Homo sapiens]                                    37   0.12 
gi|87298937 centrosomal protein 110kDa [Homo sapiens]                  37   0.12 
gi|4885375 histone cluster 1, H1c [Homo sapiens]                       34   0.79 
gi|190684675 X-ray repair cross complementing protein 1 [Homo sa...    33   1.0  
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot...    33   1.0  
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot...    33   1.0  
gi|113415504 PREDICTED: similar to ribonucleic acid binding prot...    33   1.0  
gi|169166499 PREDICTED: similar to ribonucleic acid binding prot...    33   1.0  
gi|113415498 PREDICTED: similar to ribonucleic acid binding prot...    33   1.0  
gi|88973230 PREDICTED: similar to ribonucleic acid binding prote...    33   1.0  
gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F...    33   1.0  
gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapi...    33   1.0  
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    33   1.0  
gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sap...    33   1.0  
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              33   1.8  
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    33   1.8  
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    33   1.8  
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    33   1.8  
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  33   1.8  
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    33   1.8  
gi|20070262 TNF receptor-associated factor 3 interacting protein...    32   2.3  
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    32   2.3  

>gi|73747829 ligase III, DNA, ATP-dependent isoform alpha precursor
            [Homo sapiens]
          Length = 1009

 Score = 2043 bits (5293), Expect = 0.0
 Identities = 1009/1009 (100%), Positives = 1009/1009 (100%)

Query: 1    MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQ 60
            MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQ
Sbjct: 1    MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQ 60

Query: 61   GSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIG 120
            GSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIG
Sbjct: 61   GSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIG 120

Query: 121  KVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQH 180
            KVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQH
Sbjct: 121  KVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQH 180

Query: 181  IADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAP 240
            IADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAP
Sbjct: 181  IADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAP 240

Query: 241  SSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFH 300
            SSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFH
Sbjct: 241  SSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFH 300

Query: 301  GDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQ 360
            GDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQ
Sbjct: 301  GDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQ 360

Query: 361  SKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDL 420
            SKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDL
Sbjct: 361  SKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDL 420

Query: 421  KMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTP 480
            KMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTP
Sbjct: 421  KMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTP 480

Query: 481  VQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAH 540
            VQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAH
Sbjct: 481  VQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAH 540

Query: 541  FKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYF 600
            FKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYF
Sbjct: 541  FKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYF 600

Query: 601  NDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLK 660
            NDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLK
Sbjct: 601  NDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLK 660

Query: 661  DVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGS 720
            DVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGS
Sbjct: 661  DVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGS 720

Query: 721  QKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAA 780
            QKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAA
Sbjct: 721  QKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAA 780

Query: 781  VWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTV 840
            VWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTV
Sbjct: 781  VWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTV 840

Query: 841  VAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPS 900
            VAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPS
Sbjct: 841  VAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPS 900

Query: 901  AMKVGEKLATKSSPVKVGEKRKAADETLCQTKVLLDIFTGVRLYLPPSTPDFSRLRRYFV 960
            AMKVGEKLATKSSPVKVGEKRKAADETLCQTKVLLDIFTGVRLYLPPSTPDFSRLRRYFV
Sbjct: 901  AMKVGEKLATKSSPVKVGEKRKAADETLCQTKVLLDIFTGVRLYLPPSTPDFSRLRRYFV 960

Query: 961  AFDGDLVQEFDMTSATHVLGSRDKNPAAQQVSPEWIWACIRKRRLVAPC 1009
            AFDGDLVQEFDMTSATHVLGSRDKNPAAQQVSPEWIWACIRKRRLVAPC
Sbjct: 961  AFDGDLVQEFDMTSATHVLGSRDKNPAAQQVSPEWIWACIRKRRLVAPC 1009


>gi|73747844 ligase III, DNA, ATP-dependent isoform beta precursor
           [Homo sapiens]
          Length = 949

 Score = 1885 bits (4883), Expect = 0.0
 Identities = 932/932 (100%), Positives = 932/932 (100%)

Query: 1   MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQ 60
           MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQ
Sbjct: 1   MSLAFKIFFPQTLRALSRKELCLFRKHHWRDVRQFSQWSETDLLHGHPLFLRRKPVLSFQ 60

Query: 61  GSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIG 120
           GSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIG
Sbjct: 61  GSHLRSRATYLVFLPGLHVGLCSGPCEMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIG 120

Query: 121 KVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQH 180
           KVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQH
Sbjct: 121 KVVPNPFSESGGDMKEWYHIKCMFEKLERARATTKKIEDLTELEGWEELEDNEKEQITQH 180

Query: 181 IADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAP 240
           IADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAP
Sbjct: 181 IADLSSKAAGTPKKKAVVQAKLTTTGQVTSPVKGASFVTSTNPRKFSGFSAKPNNSGEAP 240

Query: 241 SSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFH 300
           SSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFH
Sbjct: 241 SSPTPKRSLSSSKCDPRHKDCLLREFRKLCAMVADNPSYNTKTQIIQDFLRKGSAGDGFH 300

Query: 301 GDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQ 360
           GDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQ
Sbjct: 301 GDVYLTVKLLLPGVIKTVYNLNDKQIVKLFSRIFNCNPDDMARDLEQGDVSETIRVFFEQ 360

Query: 361 SKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDL 420
           SKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDL
Sbjct: 361 SKSFPPAAKSLLTIQEVDEFLLRLSKLTKEDEQQQALQDIASRCTANDLKCIIRLIKHDL 420

Query: 421 KMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTP 480
           KMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTP
Sbjct: 421 KMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLMTP 480

Query: 481 VQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAH 540
           VQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAH
Sbjct: 481 VQPMLAEACKSVEYAMKKCPNGMFSEIKYDGERVQVHKNGDHFSYFSRSLKPVLPHKVAH 540

Query: 541 FKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYF 600
           FKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYF
Sbjct: 541 FKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKKAAFQDANVCLFVFDCIYF 600

Query: 601 NDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLK 660
           NDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLK
Sbjct: 601 NDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRVIQEGLEGLVLK 660

Query: 661 DVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGS 720
           DVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGS
Sbjct: 661 DVKGTYEPGKRHWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKGGMMSIFLMGCYDPGS 720

Query: 721 QKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAA 780
           QKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAA
Sbjct: 721 QKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNKIYYPDFIVPDPKKAA 780

Query: 781 VWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTV 840
           VWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTV
Sbjct: 781 VWEITGAEFSKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTV 840

Query: 841 VAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPS 900
           VAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPS
Sbjct: 841 VAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPS 900

Query: 901 AMKVGEKLATKSSPVKVGEKRKAADETLCQTK 932
           AMKVGEKLATKSSPVKVGEKRKAADETLCQTK
Sbjct: 901 AMKVGEKLATKSSPVKVGEKRKAADETLCQTK 932


>gi|4557719 DNA ligase I [Homo sapiens]
          Length = 919

 Score =  175 bits (443), Expect = 2e-43
 Identities = 124/373 (33%), Positives = 188/373 (50%), Gaps = 35/373 (9%)

Query: 480 PVQPMLAEACKSVEYAMKKCPNGMFS-EIKYDGERVQVHK-NGDHFSYFSRSLKPVLPHK 537
           P++PMLA   + +   +K+     F+ E KYDG+R Q+H   G     FSR+ +      
Sbjct: 539 PLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQED----N 594

Query: 538 VAHFKDYIPQA----FPGGHSMILDSEVLLIDNKTGKPLPFGTLGVHKK----AAFQDAN 589
              + D I +      P   S ILD+E +  D +  +  PF  L   K+    A+     
Sbjct: 595 TGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQ 654

Query: 590 VCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEMKRVTKALDLADMITRV 649
           VCL+ FD IY N  SL+  PL  RR+ L +N VE     +F+          +A+ + + 
Sbjct: 655 VCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQS 714

Query: 650 IQEGLEGLVLK--DVKGTYEPGKR--HWLKVKKDYLNEGAMADTADLVVLGAFYGQGSKG 705
           +++  EGL++K  DV  TYE  KR  +WLK+KKDYL+   + DT DLVV+GA+ G+G + 
Sbjct: 715 VKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLD--GVGDTLDLVVIGAYLGRGKRA 772

Query: 706 GMMSIFLMGCYDPGSQKWCTVTKCAGGHDDATLARLQNELDMVKISKDPSKIPSWLKVNK 765
           G    FL+  YD  S++   + K   G  D  L      L  + +   PS  P +++++ 
Sbjct: 773 GRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVL---PSPRP-YVRIDG 828

Query: 766 IYYPDFIVPDPKKAAVWEITGAEFSKSEAHTA--------DGISIRFPRCTRIRDDKDWK 817
              PD  + DP  +AVWE+  A+ S S  + A         GIS+RFPR  R+R+DK  +
Sbjct: 829 AVIPDHWL-DP--SAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPE 885

Query: 818 SATNLPQLKELYQ 830
            AT   Q+  LY+
Sbjct: 886 QATTSAQVACLYR 898


>gi|46255052 DNA ligase IV [Homo sapiens]
          Length = 911

 Score =  152 bits (385), Expect = 1e-36
 Identities = 149/569 (26%), Positives = 260/569 (45%), Gaps = 63/569 (11%)

Query: 300 HGDV----YLTVKLLLPGVIKT--VYNLNDKQIVKLFSRIFNCNPD--DMARDLE----- 346
           H DV    Y  ++L+LP + +    Y + +  + KL+  + N   D  D  + L      
Sbjct: 57  HKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPT 116

Query: 347 --QGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSK---LTKEDEQQQALQDIA 401
              GD  +   + +   K      K  LTIQ+V++ L  ++      ++D  +++L  + 
Sbjct: 117 GTHGDAGDFAMIAYFVLKP-RCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLI 175

Query: 402 SRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEV 461
           ++ +A + K +IR+I  DLK+    + +      +A E    + +L+ V  R LH+    
Sbjct: 176 TQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVC-RQLHDPSVG 234

Query: 462 EKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFS-EIKYDGERVQVHKNG 520
             +        +  +L +  +PMLA A   +E+  K   +  F  E K DGER+Q+HK+G
Sbjct: 235 LSD--------ISITLFSAFKPMLA-AIADIEHIEKDMKHQSFYIETKLDGERMQMHKDG 285

Query: 521 DHFSYFSRSLKPVLPHKVAH-----FKDYIPQAFPGGHSM-ILDSEVLLIDNKTGKPLPF 574
           D + YFSR+         A         +I  AF     + ILD E++  +  T   +  
Sbjct: 286 DVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQK 345

Query: 575 GT-LGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEM 633
           GT   + +     D   C  VFD +  N+  L    L +R + L      IP RI   + 
Sbjct: 346 GTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQK 405

Query: 634 KRVTKALDLADMITRVIQEGLEGLVLKDVKGTYEPGKR--HWLKVKKDYLNEGAMADTAD 691
            +     ++ D +   I +  EG+++K     Y+P KR   WLK+K +Y++   + D  D
Sbjct: 406 TQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVS--GLMDELD 463

Query: 692 LVVLGAFYGQGSKGGMMSIFLMGCYD---PGSQK--WCTVTKCAGGHDDATLARLQN-EL 745
           ++++G ++G+GS+GGMMS FL    +   PG +   + T+++   G    T+  L +  L
Sbjct: 464 ILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSG---CTMKELYDLGL 520

Query: 746 DMVKISK------DPSKIPSWLKVNKIYYPDFIVPDPKKAAVWEITGAEFSKSEAHTADG 799
            + K  K       PS I    +  ++Y       +P  + + +I  AE   S+ +   G
Sbjct: 521 KLAKYWKPFHRKAPPSSILCGTEKPEVYI------EPCNSVIVQIKAAEIVPSDMYKT-G 573

Query: 800 ISIRFPRCTRIRDDKDWKSATNLPQLKEL 828
            ++RFPR  +IRDDK+W     L  L++L
Sbjct: 574 CTLRFPRIEKIRDDKEWHECMTLDDLEQL 602


>gi|23199993 DNA ligase IV [Homo sapiens]
          Length = 911

 Score =  152 bits (385), Expect = 1e-36
 Identities = 149/569 (26%), Positives = 260/569 (45%), Gaps = 63/569 (11%)

Query: 300 HGDV----YLTVKLLLPGVIKT--VYNLNDKQIVKLFSRIFNCNPD--DMARDLE----- 346
           H DV    Y  ++L+LP + +    Y + +  + KL+  + N   D  D  + L      
Sbjct: 57  HKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPT 116

Query: 347 --QGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSK---LTKEDEQQQALQDIA 401
              GD  +   + +   K      K  LTIQ+V++ L  ++      ++D  +++L  + 
Sbjct: 117 GTHGDAGDFAMIAYFVLKP-RCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLI 175

Query: 402 SRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEV 461
           ++ +A + K +IR+I  DLK+    + +      +A E    + +L+ V  R LH+    
Sbjct: 176 TQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVC-RQLHDPSVG 234

Query: 462 EKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFS-EIKYDGERVQVHKNG 520
             +        +  +L +  +PMLA A   +E+  K   +  F  E K DGER+Q+HK+G
Sbjct: 235 LSD--------ISITLFSAFKPMLA-AIADIEHIEKDMKHQSFYIETKLDGERMQMHKDG 285

Query: 521 DHFSYFSRSLKPVLPHKVAH-----FKDYIPQAFPGGHSM-ILDSEVLLIDNKTGKPLPF 574
           D + YFSR+         A         +I  AF     + ILD E++  +  T   +  
Sbjct: 286 DVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQK 345

Query: 575 GT-LGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEM 633
           GT   + +     D   C  VFD +  N+  L    L +R + L      IP RI   + 
Sbjct: 346 GTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQK 405

Query: 634 KRVTKALDLADMITRVIQEGLEGLVLKDVKGTYEPGKR--HWLKVKKDYLNEGAMADTAD 691
            +     ++ D +   I +  EG+++K     Y+P KR   WLK+K +Y++   + D  D
Sbjct: 406 TQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVS--GLMDELD 463

Query: 692 LVVLGAFYGQGSKGGMMSIFLMGCYD---PGSQK--WCTVTKCAGGHDDATLARLQN-EL 745
           ++++G ++G+GS+GGMMS FL    +   PG +   + T+++   G    T+  L +  L
Sbjct: 464 ILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSG---CTMKELYDLGL 520

Query: 746 DMVKISK------DPSKIPSWLKVNKIYYPDFIVPDPKKAAVWEITGAEFSKSEAHTADG 799
            + K  K       PS I    +  ++Y       +P  + + +I  AE   S+ +   G
Sbjct: 521 KLAKYWKPFHRKAPPSSILCGTEKPEVYI------EPCNSVIVQIKAAEIVPSDMYKT-G 573

Query: 800 ISIRFPRCTRIRDDKDWKSATNLPQLKEL 828
            ++RFPR  +IRDDK+W     L  L++L
Sbjct: 574 CTLRFPRIEKIRDDKEWHECMTLDDLEQL 602


>gi|148539894 DNA ligase IV [Homo sapiens]
          Length = 911

 Score =  152 bits (385), Expect = 1e-36
 Identities = 149/569 (26%), Positives = 260/569 (45%), Gaps = 63/569 (11%)

Query: 300 HGDV----YLTVKLLLPGVIKT--VYNLNDKQIVKLFSRIFNCNPD--DMARDLE----- 346
           H DV    Y  ++L+LP + +    Y + +  + KL+  + N   D  D  + L      
Sbjct: 57  HKDVTDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPT 116

Query: 347 --QGDVSETIRVFFEQSKSFPPAAKSLLTIQEVDEFLLRLSK---LTKEDEQQQALQDIA 401
              GD  +   + +   K      K  LTIQ+V++ L  ++      ++D  +++L  + 
Sbjct: 117 GTHGDAGDFAMIAYFVLKP-RCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLI 175

Query: 402 SRCTANDLKCIIRLIKHDLKMNSGAKHVLDALDPNAYEAFKASRNLQDVVERVLHNAQEV 461
           ++ +A + K +IR+I  DLK+    + +      +A E    + +L+ V  R LH+    
Sbjct: 176 TQSSALEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVC-RQLHDPSVG 234

Query: 462 EKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFS-EIKYDGERVQVHKNG 520
             +        +  +L +  +PMLA A   +E+  K   +  F  E K DGER+Q+HK+G
Sbjct: 235 LSD--------ISITLFSAFKPMLA-AIADIEHIEKDMKHQSFYIETKLDGERMQMHKDG 285

Query: 521 DHFSYFSRSLKPVLPHKVAH-----FKDYIPQAFPGGHSM-ILDSEVLLIDNKTGKPLPF 574
           D + YFSR+         A         +I  AF     + ILD E++  +  T   +  
Sbjct: 286 DVYKYFSRNGYNYTDQFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQK 345

Query: 575 GT-LGVHKKAAFQDANVCLFVFDCIYFNDVSLMDRPLCERRKFLHDNMVEIPNRIMFSEM 633
           GT   + +     D   C  VFD +  N+  L    L +R + L      IP RI   + 
Sbjct: 346 GTKFDIKRMVEDSDLQTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQK 405

Query: 634 KRVTKALDLADMITRVIQEGLEGLVLKDVKGTYEPGKR--HWLKVKKDYLNEGAMADTAD 691
            +     ++ D +   I +  EG+++K     Y+P KR   WLK+K +Y++   + D  D
Sbjct: 406 TQAHTKNEVIDALNEAIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVS--GLMDELD 463

Query: 692 LVVLGAFYGQGSKGGMMSIFLMGCYD---PGSQK--WCTVTKCAGGHDDATLARLQN-EL 745
           ++++G ++G+GS+GGMMS FL    +   PG +   + T+++   G    T+  L +  L
Sbjct: 464 ILIVGGYWGKGSRGGMMSHFLCAVAEKPPPGEKPSVFHTLSRVGSG---CTMKELYDLGL 520

Query: 746 DMVKISK------DPSKIPSWLKVNKIYYPDFIVPDPKKAAVWEITGAEFSKSEAHTADG 799
            + K  K       PS I    +  ++Y       +P  + + +I  AE   S+ +   G
Sbjct: 521 KLAKYWKPFHRKAPPSSILCGTEKPEVYI------EPCNSVIVQIKAAEIVPSDMYKT-G 573

Query: 800 ISIRFPRCTRIRDDKDWKSATNLPQLKEL 828
            ++RFPR  +IRDDK+W     L  L++L
Sbjct: 574 CTLRFPRIEKIRDDKEWHECMTLDDLEQL 602


>gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo
           sapiens]
          Length = 1014

 Score = 53.9 bits (128), Expect = 7e-07
 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 3/111 (2%)

Query: 87  EMAEQRFCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEK 146
           E +++ + V+YAK G A CKKC E I K   R+  +V +P  +  G +  WYH  C ++ 
Sbjct: 3   ESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFD--GKVPHWYHFSCFWKV 60

Query: 147 LERARATTKKIEDLTELEGWEELEDNEKEQITQHIADLSSKAAGTPKKKAV 197
               R    +++  +EL  W++ +  +K      +        G+  +K +
Sbjct: 61  GHSIRHPDVEVDGFSELR-WDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTL 110



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 2/95 (2%)

Query: 93  FCVDYAKRGTAGCKKCKEKIVKGVCRIGKVVPNPFSESGGDMKEWYHIKCMFEKLERARA 152
           F  +YAK   + CK C EKI KG  R+ K + +P     G +  WYH  C  +   R   
Sbjct: 113 FAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVK--NREEL 170

Query: 153 TTKKIEDLTELEGWEELEDNEKEQITQHIADLSSK 187
             +     ++L+G+  L   +KE + + +  + S+
Sbjct: 171 GFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSE 205


>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
           sapiens]
          Length = 699

 Score = 38.1 bits (87), Expect = 0.042
 Identities = 41/133 (30%), Positives = 59/133 (44%), Gaps = 33/133 (24%)

Query: 790 SKSEAHTADGISIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEKADFTVVAGDEGSST 849
           S  E  T   ++   P+ T        K+A +LP  K+  Q S++ +           S 
Sbjct: 432 SSEEEKTKKMVATTKPKATA-------KAALSLPA-KQAPQGSRDSSS---------DSD 474

Query: 850 TGGSSEENKGPSGSAVSRK--------APSKPSASTKKAEGKLSNSNSKDGNMQTAKPSA 901
           +  S EE +  S SAV +K        APSKP AS KK + + SNS+S D + +  +   
Sbjct: 475 SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKP-ASAKKGKAESSNSSSSDDSSEEEE--- 530

Query: 902 MKVGEKLATKSSP 914
               EKL  K SP
Sbjct: 531 ----EKLKGKGSP 539



 Score = 37.7 bits (86), Expect = 0.055
 Identities = 27/83 (32%), Positives = 40/83 (48%), Gaps = 6/83 (7%)

Query: 840 VVAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGK--LSNSNSKDGNMQTA 897
           V + ++ S  +  SSEE K P   AV  KA +KP  + K AE     S+S+S + +   +
Sbjct: 319 VESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPS 378

Query: 898 KPSAMKVGEK----LATKSSPVK 916
           KP+           + TKS  VK
Sbjct: 379 KPAGTTKNSSNKPAVTTKSPAVK 401


>gi|93102361 palladin [Homo sapiens]
          Length = 1106

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 7/97 (7%)

Query: 452 ERVLHNAQE--VEKEPGQRRALSVQASLMTPVQPMLAEACKSVEYAMKKCPNGMFSEIKY 509
           E +L+N Q     +E   RR L   ++ +  +Q    E     EY +  C   + SEI+Y
Sbjct: 692 EDLLNNGQPRLTYEERMARRLLGADSATVFNIQEPEEETANQ-EYKVSSCEQRLISEIEY 750

Query: 510 DGERVQVHKNGDHFSY----FSRSLKPVLPHKVAHFK 542
             ER  V ++GD   Y        + P    K+ H+K
Sbjct: 751 RLERSPVDESGDEVQYGDVPVENGMAPFFEMKLKHYK 787


>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
          Length = 2325

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 31/106 (29%), Positives = 48/106 (45%), Gaps = 14/106 (13%)

Query: 377 VDEFLLRLSKLTKE----DEQQQALQDIASRCTANDLKCIIRLIKHDLKMNSGAKHVLDA 432
           +DE L R++K T+E    +EQ    Q  A+     DL+ +I          SG +  L  
Sbjct: 578 LDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVI----------SGLQEYLGT 627

Query: 433 LDPNAYEAFKASRNLQDVVERVLHNAQEVEKEPGQRRALSVQASLM 478
           +   A +A    R L+D  E +L    EVE+E  Q   +++ A  M
Sbjct: 628 IKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENM 673


>gi|4885375 histone cluster 1, H1c [Homo sapiens]
          Length = 213

 Score = 33.9 bits (76), Expect = 0.79
 Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 10/90 (11%)

Query: 845 EGSSTTGGSSEENKGPSGSAVSR------KAPSKPSASTKK----AEGKLSNSNSKDGNM 894
           +G+  +G      K  SG A  +        P KP  + KK    A G     ++K    
Sbjct: 97  KGTGASGSFKLNKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPK 156

Query: 895 QTAKPSAMKVGEKLATKSSPVKVGEKRKAA 924
           +  KP+A  V +K+A      KV + +KAA
Sbjct: 157 KAKKPAAATVTKKVAKSPKKAKVAKPKKAA 186


>gi|190684675 X-ray repair cross complementing protein 1 [Homo
            sapiens]
          Length = 633

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 23/85 (27%), Positives = 42/85 (49%), Gaps = 13/85 (15%)

Query: 934  LLDIFTGVRLYLPPSTPDFSR--LRRYFVAFDGDLVQEFDMTSATHVLGSRDKNPAAQQ- 990
            L D F G   +L    P   R  L RY  AF+G+L +++       V+ +++ +P+ ++ 
Sbjct: 539  LPDFFQGKHFFLYGEFPGDERRKLIRYVTAFNGEL-EDYMSDRVQFVITAQEWDPSFEEA 597

Query: 991  ---------VSPEWIWACIRKRRLV 1006
                     V P WI++C  K++L+
Sbjct: 598  LMDNPSLAFVRPRWIYSCNEKQKLL 622


>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 6 [Homo sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 2 [Homo sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|113415504 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|169166499 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|113415498 PREDICTED: similar to ribonucleic acid binding protein
           S1 [Homo sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|88973230 PREDICTED: similar to ribonucleic acid binding protein
           S1 isoform 3 [Homo sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRHSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|53832007 calcium channel, voltage-dependent, L type, alpha 1F
            subunit [Homo sapiens]
          Length = 1977

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 19/63 (30%), Positives = 29/63 (46%)

Query: 521  DHFSYFSRSLKPVLPHKVAHFKDYIPQAFPGGHSMILDSEVLLIDNKTGKPLPFGTLGVH 580
            D+F Y +R    + PH +  FK    +  PG    I   +V+ +  +   PL FG L  H
Sbjct: 1442 DNFDYLTRDWSILGPHHLDEFKRIWSEYDPGAKGRIKHLDVVALLRRIQPPLGFGKLCPH 1501

Query: 581  KKA 583
            + A
Sbjct: 1502 RVA 1504


>gi|6857826 RNA-binding protein S1, serine-rich domain [Homo
           sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
            sapiens]
          Length = 1710

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 31/132 (23%), Positives = 55/132 (41%), Gaps = 11/132 (8%)

Query: 812  DDKDWKSATNLPQLKELYQ---LSKEKADFTVVAGDEGSSTTGGSSEENKGPSGSAVSRK 868
            DD D K      Q +  Y    LS++ A    ++G   S      +++NK      V  +
Sbjct: 1291 DDPDKKPQAKQLQTRADYLIKLLSRDLAKKEALSGAGSSKRRKARAKKNKAMKSIKVKEE 1350

Query: 869  APSK----PSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVGEKLATKSSPVKVGEKRKAA 924
              S     PS  + + + KLS S S DG  ++ K S       +     PV + E+ +  
Sbjct: 1351 IKSDSSPLPSEKSDEDDDKLSESKS-DGRERSKKSSVSDAPVHITASGEPVPISEESEEL 1409

Query: 925  DE---TLCQTKV 933
            D+   ++C+ ++
Sbjct: 1410 DQKTFSICKERM 1421


>gi|18379334 RNA-binding protein S1, serine-rich domain [Homo
           sapiens]
          Length = 305

 Score = 33.5 bits (75), Expect = 1.0
 Identities = 44/143 (30%), Positives = 59/143 (41%), Gaps = 11/143 (7%)

Query: 801 SIRFPRCTRIRDDKDWKSATNLPQLKELYQLSKEK---ADFTVV--AGDEGSSTTGG--S 853
           S R P  T+ +D  D KS       K   + S EK    D T    +   GSS+T    S
Sbjct: 22  STRAPSPTKRKDRSDEKSKDRSKD-KGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSS 80

Query: 854 SEENKGPSGSAVSRKAPSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVG--EKLATK 911
           S  + G S S  S    S  SAS++      S S+S   +  +  PS  +     +  +K
Sbjct: 81  STSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK 140

Query: 912 SSPVKVGEK-RKAADETLCQTKV 933
           S P K  EK RK    +   TKV
Sbjct: 141 SKPPKRDEKERKRRSPSPKPTKV 163


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 29/118 (24%), Positives = 50/118 (42%), Gaps = 6/118 (5%)

Query: 816 WKSATNLPQLKELYQLSKEKADFTVVAGDEGSSTTGGSSEENKGPSGSAVSRK----APS 871
           WK      +L + + L KE+A     A    +   GGSS  +   SG     +    A +
Sbjct: 250 WKEGCLQSELIQ-FHLKKERAAAAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASA 308

Query: 872 KPSASTKKAEGKLSNSNSKDGNMQ-TAKPSAMKVGEKLATKSSPVKVGEKRKAADETL 928
            P A+  +   + +  ++  G MQ  A PS+    ++L  +    +  EK +  +ETL
Sbjct: 309 SPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETL 366


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
           sapiens]
          Length = 1751

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 823 PQLKELYQLSKEKADFTVVAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEG 882
           PQ+  ++ L +E  D    +GD GS   G + E  +  +G+A+  + P+ P  +T    G
Sbjct: 644 PQVSPMHCLDEEGDDSDGASGDSGSG-LGDARELLREETGAALKPRLPAPPPVTTPPLAG 702

Query: 883 KLSNSNSKDGNMQ 895
             S  +S+   ++
Sbjct: 703 GSSTEDSRSEEVE 715


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 823 PQLKELYQLSKEKADFTVVAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEG 882
           PQ+  ++ L +E  D    +GD GS   G + E  +  +G+A+  + P+ P  +T    G
Sbjct: 229 PQVSPMHCLDEEGDDSDGASGDSGSG-LGDARELLREETGAALKPRLPAPPPVTTPPLAG 287

Query: 883 KLSNSNSKDGNMQ 895
             S  +S+   ++
Sbjct: 288 GSSTEDSRSEEVE 300


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 823 PQLKELYQLSKEKADFTVVAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEG 882
           PQ+  ++ L +E  D    +GD GS   G + E  +  +G+A+  + P+ P  +T    G
Sbjct: 409 PQVSPMHCLDEEGDDSDGASGDSGSG-LGDARELLREETGAALKPRLPAPPPVTTPPLAG 467

Query: 883 KLSNSNSKDGNMQ 895
             S  +S+   ++
Sbjct: 468 GSSTEDSRSEEVE 480


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 24/77 (31%), Positives = 36/77 (46%), Gaps = 4/77 (5%)

Query: 843  GDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTK-KAEGK---LSNSNSKDGNMQTAK 898
            G  GSS +  SS+    P  S +++   S  S+STK K +GK   L N +    N+  + 
Sbjct: 1136 GSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQGKPSSLMNPSLSKPNISPSH 1195

Query: 899  PSAMKVGEKLATKSSPV 915
                   +KLA+   PV
Sbjct: 1196 SRPPGGSDKLASPMKPV 1212


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 32.7 bits (73), Expect = 1.8
 Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 1/77 (1%)

Query: 825 LKELYQLSKEKADFTVVAGDEGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKL 884
           LK+ +  S E  D  V    E ++T   + + +  PS    +RKA S+ S S K  E K 
Sbjct: 454 LKDAFARSMELIDVAVEKAGESANTKDSADDNHLSPSRWKWARKALSETS-SNKSFENKY 512

Query: 885 SNSNSKDGNMQTAKPSA 901
              + KD + Q    S+
Sbjct: 513 QEVSQKDSHEQLNNTSS 529


>gi|20070262 TNF receptor-associated factor 3 interacting protein 1
           isoform 1 [Homo sapiens]
          Length = 691

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 20/72 (27%), Positives = 32/72 (44%)

Query: 870 PSKPSASTKKAEGKLSNSNSKDGNMQTAKPSAMKVGEKLATKSSPVKVGEKRKAADETLC 929
           P K SAS+ +   KLS+   KD   +T    + +  + L TK+S  +     +   E   
Sbjct: 302 PEKKSASSGEMSKKLSDGTFKDSKAETETEISTRASKSLTTKTSKRRSKNSVEGRKEDNI 361

Query: 930 QTKVLLDIFTGV 941
             K L  I +G+
Sbjct: 362 SAKSLDSIVSGI 373


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 32.3 bits (72), Expect = 2.3
 Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 6/103 (5%)

Query: 832  SKEKADFTVVAGD------EGSSTTGGSSEENKGPSGSAVSRKAPSKPSASTKKAEGKLS 885
            SK KA     +GD      +GS  + G+ +E +      +        S    K E K S
Sbjct: 1310 SKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKS 1369

Query: 886  NSNSKDGNMQTAKPSAMKVGEKLATKSSPVKVGEKRKAADETL 928
            +   KD   +  K  A K   K +   S  K  +K+K A++T+
Sbjct: 1370 DKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,571,158
Number of Sequences: 37866
Number of extensions: 1830230
Number of successful extensions: 7252
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 44
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 6979
Number of HSP's gapped (non-prelim): 316
length of query: 1009
length of database: 18,247,518
effective HSP length: 112
effective length of query: 897
effective length of database: 14,006,526
effective search space: 12563853822
effective search space used: 12563853822
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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