Guide to the Human Genome
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Name: LIG4 Sequence: fasta or formatted (911aa) NCBI GI: 46255052
Description:

DNA ligase IV

Referenced in:

DNases, Recombination, and DNA Repair
Replication Proteins

Other entries for this name:
alt mRNA [911aa] DNA ligase IV
alt mRNA [911aa] DNA ligase IV
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.8         53           2
 C cysteine            2.2         20           1
 D aspartate           6.5         59           2
 E glutamate           6.8         62           2
 F phenylalanine       4.3         39           1
 G glycine             5.5         50           2
 H histidine           3.1         28           1
 I isoleucine          7.4         67           2
 K lysine              9.1         83           2
 L leucine             8.9         81           2
 M methionine          3.1         28           2
 N asparagine          3.6         33           2
 P proline             4.4         40           3
 Q glutamine           3.6         33           2
 R arginine            4.7         43           2
 S serine              6.7         61           2
 T threonine           4.8         44           2
 V valine              5.0         46           2
 W tryptophan          1.1         10           1
 Y tyrosine            3.4         31           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   DNA ligase IV 
LIG4                  1.000   DNA ligase IV 
LIG4                  1.000   DNA ligase IV 
LIG3                  0.070   ligase III, DNA, ATP-dependent isoform beta precurso...
LIG3                  0.070   ligase III, DNA, ATP-dependent isoform alpha precurs...
LIG1                  0.054   DNA ligase I 
SMC1B                 0.004   SMC1 structural maintenance of chromosomes 1-like 2 ...
LOC100128069          0.004   PREDICTED: similar to alpha actin 
DYRK1A                0.004   dual-specificity tyrosine-(Y)-phosphorylation regula...
LOC653192             0.004   PREDICTED: Tripartite motif-containing protein 43-li...
TRIM43                0.004   tripartite motif-containing 43 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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