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Search of human proteins with 72198189
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo
sapiens]
(239 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens] 499 e-142
gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens] 411 e-115
gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens] 178 4e-45
gi|4757842 BCL2-like 2 protein [Homo sapiens] 153 1e-37
gi|4502363 BCL2-antagonist/killer 1 [Homo sapiens] 68 8e-12
gi|239751987 PREDICTED: hypothetical protein XP_002348091 [Homo ... 68 8e-12
gi|4502381 BCL2-like 1 isoform 2 [Homo sapiens] 64 9e-11
gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens] 63 2e-10
gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens] 62 3e-10
gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens] 61 7e-10
gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens] 60 2e-09
gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens] 58 6e-09
gi|242117893 BCL2-associated X protein isoform sigma [Homo sapiens] 58 6e-09
gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo sap... 57 1e-08
gi|14210524 BCL2-related ovarian killer [Homo sapiens] 48 7e-06
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 42 6e-04
gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo sap... 40 0.002
gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo sap... 40 0.002
gi|208431824 forkhead box I3 [Homo sapiens] 39 0.004
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 37 0.015
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 37 0.015
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 37 0.015
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 37 0.020
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 37 0.020
gi|122937321 UNC homeobox [Homo sapiens] 37 0.020
gi|189217895 KH domain-containing, RNA-binding, signal transduct... 36 0.026
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 36 0.026
gi|110832843 TBP-associated factor 4 [Homo sapiens] 36 0.034
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 36 0.034
gi|163965366 nascent polypeptide-associated complex alpha subuni... 36 0.034
>gi|72198189 B-cell lymphoma protein 2 alpha isoform [Homo sapiens]
Length = 239
Score = 499 bits (1285), Expect = e-142
Identities = 239/239 (100%), Positives = 239/239 (100%)
Query: 1 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA 60
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
Sbjct: 1 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA 60
Query: 61 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH 120
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
Sbjct: 61 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH 120
Query: 121 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY 180
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
Sbjct: 121 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY 180
Query: 181 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK 239
LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
Sbjct: 181 LNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK 239
>gi|72198346 B-cell lymphoma protein 2 beta isoform [Homo sapiens]
Length = 205
Score = 411 bits (1056), Expect = e-115
Identities = 195/195 (100%), Positives = 195/195 (100%)
Query: 1 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA 60
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA
Sbjct: 1 MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPA 60
Query: 61 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH 120
ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH
Sbjct: 61 ASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLH 120
Query: 121 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY 180
LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY
Sbjct: 121 LTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEY 180
Query: 181 LNRHLHTWIQDNGGW 195
LNRHLHTWIQDNGGW
Sbjct: 181 LNRHLHTWIQDNGGW 195
>gi|20336335 BCL2-like 1 isoform 1 [Homo sapiens]
Length = 233
Score = 178 bits (451), Expect = 4e-45
Identities = 99/199 (49%), Positives = 121/199 (60%), Gaps = 13/199 (6%)
Query: 11 NREIVMKYIHYKLSQRGYEWDA-GDVGA----APPGAAPAPGIFSSQPGHTPHPAASRDP 65
NRE+V+ ++ YKLSQ+GY W DV AP G S+ G+ A
Sbjct: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLAD--- 61
Query: 66 VARTSPLQTPAAPGAAAGPALSPVP-PVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPF 124
SP A +++ A +P V LR+AGD+F RYRR F++++SQLH+TP
Sbjct: 62 ----SPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPG 117
Query: 125 TARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRH 184
TA F VV ELFRDGVNWGRIVAFF FGG +CVESV++EM LV IA WM YLN H
Sbjct: 118 TAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIAAWMATYLNDH 177
Query: 185 LHTWIQDNGGWDAFVELYG 203
L WIQ+NGGWD FVELYG
Sbjct: 178 LEPWIQENGGWDTFVELYG 196
>gi|4757842 BCL2-like 2 protein [Homo sapiens]
Length = 193
Score = 153 bits (386), Expect = 1e-37
Identities = 74/163 (45%), Positives = 104/163 (63%), Gaps = 5/163 (3%)
Query: 82 AGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDG 141
AGP P +H +R AGD+F R+RR F+++++QLH+TP +A+ RF V +ELF+ G
Sbjct: 31 AGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGG 90
Query: 142 VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVEL 201
NWGR+VAFF FG +C ESVN+EM PLV + WM YL L WI +GGW F L
Sbjct: 91 PNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETRLADWIHSSGGWAEFTAL 150
Query: 202 YG----PSMRPLFDFSWLSLKTLLSLAL-VGACITLGAYLGHK 239
YG R L + +W S++T+L+ A+ +GA +T+GA+ K
Sbjct: 151 YGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK 193
>gi|4502363 BCL2-antagonist/killer 1 [Homo sapiens]
Length = 211
Score = 67.8 bits (164), Expect = 8e-12
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 60 AASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQL 119
AA DP T PLQ P++ G L+ + GDD +RRY +F M L
Sbjct: 53 AAPADPEMVTLPLQ-PSSTMGQVGRQLAII-----------GDDINRRYDSEFQTMLQHL 100
Query: 120 HLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTE 179
T A F + LF G+NWGR+VA FG + + ++ + + ++ +
Sbjct: 101 QPTAENAYEYFTKIATSLFESGINWGRVVALLGFGYRLALHVYQHGLTGFLGQVTRFVVD 160
Query: 180 YLNRH-LHTWIQDNGGWDAFVEL-YGPSMRPL 209
++ H + WI GGW A + L GP + L
Sbjct: 161 FMLHHCIARWIAQRGGWVAALNLGNGPILNVL 192
>gi|239751987 PREDICTED: hypothetical protein XP_002348091 [Homo
sapiens]
Length = 211
Score = 67.8 bits (164), Expect = 8e-12
Identities = 45/152 (29%), Positives = 68/152 (44%), Gaps = 14/152 (9%)
Query: 60 AASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQL 119
AA DP T PLQ P++ G L+ + GDD +RRY +F M L
Sbjct: 53 AAPADPEMVTLPLQ-PSSTMGQVGRQLAII-----------GDDINRRYDSEFQTMLQHL 100
Query: 120 HLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTE 179
T A F + LF G+NWGR+VA F + + R ++ + + ++ +
Sbjct: 101 QPTAENAYEYFTKIASSLFESGINWGRVVALLGFSYRLALHIYQRGLTGFLGQVTRFVVD 160
Query: 180 YLNRH-LHTWIQDNGGWDAFVEL-YGPSMRPL 209
++ H + WI GGW A + L GP + L
Sbjct: 161 FMLHHCIARWIAQRGGWVAALNLGNGPILNVL 192
>gi|4502381 BCL2-like 1 isoform 2 [Homo sapiens]
Length = 170
Score = 64.3 bits (155), Expect = 9e-11
Identities = 46/126 (36%), Positives = 64/126 (50%), Gaps = 13/126 (10%)
Query: 11 NREIVMKYIHYKLSQRGYEWDA-GDVGA----APPGAAPAPGIFSSQPGHTPHPAASRDP 65
NRE+V+ ++ YKLSQ+GY W DV AP G S+ G+ A
Sbjct: 5 NRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEGTESEMETPSAINGNPSWHLAD--- 61
Query: 66 VARTSPLQTPAAPGAAAGPALSPVP-PVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPF 124
SP A +++ A +P V LR+AGD+F RYRR F++++SQLH+TP
Sbjct: 62 ----SPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPG 117
Query: 125 TARGRF 130
TA F
Sbjct: 118 TAYQSF 123
>gi|20631958 BCL2-associated X protein isoform alpha [Homo sapiens]
Length = 192
Score = 63.2 bits (152), Expect = 2e-10
Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 14/133 (10%)
Query: 79 GAAAGPALSPVPPVVHLT-----LRQAGD--DFSRRYRRDFAEMSSQLHLTPFTARGRFA 131
G A AL PVP L++ GD D + +R A + + + R F
Sbjct: 40 GEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTD------SPREVFF 93
Query: 132 TVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQ 190
V ++F DG NWGR+VA F F + ++++ ++ L+ I W ++L L WIQ
Sbjct: 94 RVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQ 153
Query: 191 DNGGWDAFVELYG 203
D GGWD + +G
Sbjct: 154 DQGGWDGLLSYFG 166
>gi|4757840 BCL2-related protein A1 isoform 1 [Homo sapiens]
Length = 175
Score = 62.4 bits (150), Expect = 3e-10
Identities = 32/85 (37%), Positives = 53/85 (62%), Gaps = 5/85 (5%)
Query: 125 TARGRFATVVEELFRDGV-NWGRIVAFFEFGGVMCVESVNREMSPLVD---NIALWMTEY 180
TAR F V+E+ F DG+ NWGRIV F F G++ + + ++++P VD I+ ++ E+
Sbjct: 66 TARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEF 125
Query: 181 LNRHLHTWIQDNGGWD-AFVELYGP 204
+ + WI+ NGGW+ FV+ + P
Sbjct: 126 IMNNTGEWIRQNGGWENGFVKKFEP 150
>gi|20631964 BCL2-associated X protein isoform delta [Homo sapiens]
Length = 143
Score = 61.2 bits (147), Expect = 7e-10
Identities = 27/75 (36%), Positives = 42/75 (56%), Gaps = 1/75 (1%)
Query: 130 FATVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTW 188
F V ++F DG NWGR+VA F F + ++++ ++ L+ I W ++L L W
Sbjct: 43 FFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGW 102
Query: 189 IQDNGGWDAFVELYG 203
IQD GGWD + +G
Sbjct: 103 IQDQGGWDGLLSYFG 117
>gi|168480072 BCL2-related protein A1 isoform 2 [Homo sapiens]
Length = 163
Score = 59.7 bits (143), Expect = 2e-09
Identities = 29/75 (38%), Positives = 47/75 (62%), Gaps = 4/75 (5%)
Query: 125 TARGRFATVVEELFRDGV-NWGRIVAFFEFGGVMCVESVNREMSPLVD---NIALWMTEY 180
TAR F V+E+ F DG+ NWGRIV F F G++ + + ++++P VD I+ ++ E+
Sbjct: 66 TARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEF 125
Query: 181 LNRHLHTWIQDNGGW 195
+ + WI+ NGGW
Sbjct: 126 IMNNTGEWIRQNGGW 140
>gi|4757838 BCL2-associated X protein isoform beta [Homo sapiens]
Length = 218
Score = 58.2 bits (139), Expect = 6e-09
Identities = 42/139 (30%), Positives = 64/139 (46%), Gaps = 14/139 (10%)
Query: 79 GAAAGPALSPVPPVVHLT-----LRQAGD--DFSRRYRRDFAEMSSQLHLTPFTARGRFA 131
G A AL PVP L++ GD D + +R A + + + R F
Sbjct: 40 GEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTD------SPREVFF 93
Query: 132 TVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQ 190
V ++F DG NWGR+VA F F + ++++ ++ L+ I W ++L L WIQ
Sbjct: 94 RVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQ 153
Query: 191 DNGGWDAFVELYGPSMRPL 209
D GGW ++ P R L
Sbjct: 154 DQGGWVRLLKPPHPHHRAL 172
>gi|242117893 BCL2-associated X protein isoform sigma [Homo sapiens]
Length = 179
Score = 58.2 bits (139), Expect = 6e-09
Identities = 40/133 (30%), Positives = 62/133 (46%), Gaps = 14/133 (10%)
Query: 79 GAAAGPALSPVPPVVHLT-----LRQAGD--DFSRRYRRDFAEMSSQLHLTPFTARGRFA 131
G A AL PVP L++ GD D + +R A + + + R F
Sbjct: 40 GEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTD------SPREVFF 93
Query: 132 TVVEELFRDG-VNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQ 190
V ++F DG NWGR+VA F F + ++++ ++ L+ I W ++L L WIQ
Sbjct: 94 RVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQ 153
Query: 191 DNGGWDAFVELYG 203
D GGW + + G
Sbjct: 154 DQGGWTVTIFVAG 166
>gi|11386165 myeloid cell leukemia sequence 1 isoform 1 [Homo
sapiens]
Length = 350
Score = 57.4 bits (137), Expect = 1e-08
Identities = 37/112 (33%), Positives = 56/112 (50%), Gaps = 9/112 (8%)
Query: 96 TLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGV-NWGRIVAFFEFG 154
TLR+ GD R + F M +L + + V+ +F DGV NWGRIV FG
Sbjct: 212 TLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFG 271
Query: 155 GVMC--VESVNRE--MSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELY 202
+ ++++N+E + PL ++I T+ L R W+ GWD FVE +
Sbjct: 272 AFVAKHLKTINQESCIEPLAESI----TDVLVRTKRDWLVKQRGWDGFVEFF 319
>gi|14210524 BCL2-related ovarian killer [Homo sapiens]
Length = 212
Score = 48.1 bits (113), Expect = 7e-06
Identities = 36/182 (19%), Positives = 67/182 (36%), Gaps = 50/182 (27%)
Query: 17 KYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPA 76
+Y+H +L + G W +AP AAP PG +
Sbjct: 37 EYVHARLLRAGLSW------SAPERAAPVPGRLAE------------------------- 65
Query: 77 APGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFT---ARGRFATV 133
V L + GD+ + ++ QLH++ + F V
Sbjct: 66 ----------------VCAVLLRLGDELEMIRPSVYRNVARQLHISLQSEPVVTDAFLAV 109
Query: 134 VEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNG 193
+F G+ WG++V+ + + V+ V + +V + + E++ + L TW++ G
Sbjct: 110 AGHIFSAGITWGKVVSLYAVAAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLATWLRRRG 169
Query: 194 GW 195
GW
Sbjct: 170 GW 171
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 41.6 bits (96), Expect = 6e-04
Identities = 24/52 (46%), Positives = 27/52 (51%), Gaps = 6/52 (11%)
Query: 35 VGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSP----LQTPAAPGAAA 82
VGA PPGAAPAP F P H P A DP T P ++TP PG +
Sbjct: 39 VGAWPPGAAPAP--FQYTPDHVVGPGADIDPTQITFPGCICVKTPCLPGTCS 88
>gi|56549666 tyrosine kinase, non-receptor, 2 isoform 1 [Homo
sapiens]
Length = 1038
Score = 39.7 bits (91), Expect = 0.002
Identities = 28/91 (30%), Positives = 36/91 (39%), Gaps = 6/91 (6%)
Query: 39 PPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPV------PPV 92
PPG++P P SS PG T S + + Q APG AGP + P+
Sbjct: 797 PPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSS 856
Query: 93 VHLTLRQAGDDFSRRYRRDFAEMSSQLHLTP 123
H L + RY+R E S TP
Sbjct: 857 THYYLLPERPSYLERYQRFLREAQSPEEPTP 887
>gi|58331191 tyrosine kinase, non-receptor, 2 isoform 2 [Homo
sapiens]
Length = 1086
Score = 39.7 bits (91), Expect = 0.002
Identities = 28/91 (30%), Positives = 36/91 (39%), Gaps = 6/91 (6%)
Query: 39 PPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPV------PPV 92
PPG++P P SS PG T S + + Q APG AGP + P+
Sbjct: 875 PPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPGPRAGPCILPIVRDGKKVSS 934
Query: 93 VHLTLRQAGDDFSRRYRRDFAEMSSQLHLTP 123
H L + RY+R E S TP
Sbjct: 935 THYYLLPERPSYLERYQRFLREAQSPEEPTP 965
>gi|208431824 forkhead box I3 [Homo sapiens]
Length = 420
Score = 38.9 bits (89), Expect = 0.004
Identities = 24/55 (43%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 37 AAPPGAAPAPGIFSSQPG-HTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVP 90
AAPP AA P ++ + PG P AA+ A P PGAAAGP L P P
Sbjct: 43 AAPPAAAANPYLWLNGPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPP 97
Score = 29.6 bits (65), Expect = 2.4
Identities = 22/72 (30%), Positives = 26/72 (36%), Gaps = 14/72 (19%)
Query: 28 YEWDAGD-VGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQ------------- 73
Y W G VG P AA A + P P P A+ P + P
Sbjct: 53 YLWLNGPGVGGPPSAAAAAAAAYLGAPPPPPPPGAAAGPFLQPPPAAGTFGCSQRPFAQP 112
Query: 74 TPAAPGAAAGPA 85
PAAP + A PA
Sbjct: 113 APAAPASPAAPA 124
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 37.0 bits (84), Expect = 0.015
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 8/85 (9%)
Query: 37 AAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPA-APGAAAGPALSPVPPVVHL 95
AAP A A + + P P PA + PVA +P PA AP A PA P
Sbjct: 155 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAP----- 209
Query: 96 TLRQAGDDFSRRYRRDFAEMSSQLH 120
+++ + + + +R ++ QLH
Sbjct: 210 --QESAEQGANQGQRGQEPLADQLH 232
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 37.0 bits (84), Expect = 0.015
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 8/85 (9%)
Query: 37 AAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPA-APGAAAGPALSPVPPVVHL 95
AAP A A + + P P PA + PVA +P PA AP A PA P
Sbjct: 155 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAP----- 209
Query: 96 TLRQAGDDFSRRYRRDFAEMSSQLH 120
+++ + + + +R ++ QLH
Sbjct: 210 --QESAEQGANQGQRGQEPLADQLH 232
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 37.0 bits (84), Expect = 0.015
Identities = 25/85 (29%), Positives = 38/85 (44%), Gaps = 8/85 (9%)
Query: 37 AAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPA-APGAAAGPALSPVPPVVHL 95
AAP A A + + P P PA + PVA +P PA AP A PA P
Sbjct: 166 AAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPAPDAAP----- 220
Query: 96 TLRQAGDDFSRRYRRDFAEMSSQLH 120
+++ + + + +R ++ QLH
Sbjct: 221 --QESAEQGANQGQRGQEPLADQLH 243
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 36.6 bits (83), Expect = 0.020
Identities = 39/127 (30%), Positives = 52/127 (40%), Gaps = 15/127 (11%)
Query: 33 GDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVA-RTSPLQTPAAP-GAAAGPA----- 85
G + APP A P + P P A R P A T L +PA P A+ G A
Sbjct: 1994 GSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPASLGRAELHPV 2053
Query: 86 -LSPVPPVVHLTLRQAGDDFSRR--YRRDFAEMSSQLHLTPFTARGRFATVVEELFR--- 139
L P L+ G SR R F+ ++S+L TP T G F T +L++
Sbjct: 2054 ELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQAS 2113
Query: 140 --DGVNW 144
D + W
Sbjct: 2114 PPDALRW 2120
Score = 32.3 bits (72), Expect = 0.37
Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 2/51 (3%)
Query: 38 APPGAAPA--PGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPAL 86
APP A P P + P P P + A+ P Q+ PG AA P L
Sbjct: 519 APPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTL 569
Score = 30.8 bits (68), Expect = 1.1
Identities = 23/73 (31%), Positives = 27/73 (36%), Gaps = 5/73 (6%)
Query: 23 LSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGH----TPHPAASRDPVARTSPLQTPAAP 78
L Q E D G PP P P +S PG P P SR P+ P P P
Sbjct: 810 LRQAADEDDKGMRSETPP-VPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPP 868
Query: 79 GAAAGPALSPVPP 91
G+ + PP
Sbjct: 869 GSDEVAKIQTPPP 881
Score = 30.4 bits (67), Expect = 1.4
Identities = 20/60 (33%), Positives = 25/60 (41%), Gaps = 4/60 (6%)
Query: 32 AGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPP 91
A VG+ G P ++ P P +SR R P + P AP AGP P PP
Sbjct: 903 ARGVGSGGQGPPPPRRESRTETRWGPRPGSSR----RGIPPEEPGAPPRRAGPIKKPPPP 958
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 36.6 bits (83), Expect = 0.020
Identities = 20/52 (38%), Positives = 21/52 (40%)
Query: 39 PPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVP 90
P G+ PAP S H P PA S PV P PG A P P P
Sbjct: 682 PVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPP 733
Score = 30.4 bits (67), Expect = 1.4
Identities = 18/45 (40%), Positives = 20/45 (44%), Gaps = 1/45 (2%)
Query: 42 AAPAPGIFSSQPGHTPHPA-ASRDPVARTSPLQTPAAPGAAAGPA 85
AAPAP +QPG PA A +PV P P A PA
Sbjct: 94 AAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAAAVETAPA 138
Score = 30.0 bits (66), Expect = 1.8
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 1/51 (1%)
Query: 51 SQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAG 101
SQ G + P A P+A +SP T A P A PA S +P T QAG
Sbjct: 1369 SQAGPSNPPGAPPAPLAPSSPPVT-ALPQDGAAPATSTMPEPASGTASQAG 1418
Score = 29.3 bits (64), Expect = 3.2
Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 6/53 (11%)
Query: 39 PPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPP 91
PP + P P + PG P P+A+ +PL AP L PVPP
Sbjct: 711 PPPSTPMP----TGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVV--PLQPVPP 757
Score = 28.9 bits (63), Expect = 4.1
Identities = 17/46 (36%), Positives = 18/46 (39%), Gaps = 1/46 (2%)
Query: 39 PPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGP 84
PPGA PAP + S P T P P T P A GP
Sbjct: 1376 PPGAPPAP-LAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGP 1420
Score = 28.1 bits (61), Expect = 7.0
Identities = 25/78 (32%), Positives = 32/78 (41%), Gaps = 17/78 (21%)
Query: 36 GAAPPGAA---PAPGIFSSQP--------GHTPH---PAASRDPVARTSPLQTPAA---P 78
G PP A P P + + QP H P PA+ A+ PLQ P A P
Sbjct: 728 GQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQP 787
Query: 79 GAAAGPALSPVPPVVHLT 96
A P + P+P V +T
Sbjct: 788 LAQVPPQMPPIPVVPPIT 805
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 36.6 bits (83), Expect = 0.020
Identities = 23/55 (41%), Positives = 29/55 (52%), Gaps = 11/55 (20%)
Query: 31 DAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPA 85
DAG G APP AP+P +PG P P+ + +P P PGAAAGP+
Sbjct: 478 DAGTAGPAPPPPAPSP-----RPGPRP-PSPAEEPATCGVP-----EPGAAAGPS 521
>gi|189217895 KH domain-containing, RNA-binding, signal
transduction-associated protein 2 [Homo sapiens]
Length = 349
Score = 36.2 bits (82), Expect = 0.026
Identities = 24/71 (33%), Positives = 28/71 (39%), Gaps = 2/71 (2%)
Query: 33 GDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPV 92
G GA PP P G+ + + A PVAR P TP A GA P PP
Sbjct: 205 GRGGAIPPPPPPGRGVLTPRGSTVTRGALPVPPVARGVP--TPRARGAPTVPGYRAPPPP 262
Query: 93 VHLTLRQAGDD 103
H + G D
Sbjct: 263 AHEAYEEYGYD 273
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 36.2 bits (82), Expect = 0.026
Identities = 22/47 (46%), Positives = 28/47 (59%), Gaps = 2/47 (4%)
Query: 47 GIFSSQPGHTPHPAASRDPVARTSPLQTPA-APGAAAGPALSPVPPV 92
G SS PG PAAS+ PV + LQ+P+ G AGPA P+PP+
Sbjct: 467 GSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPA-CPLPPL 512
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 35.8 bits (81), Expect = 0.034
Identities = 18/49 (36%), Positives = 22/49 (44%)
Query: 37 AAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPA 85
AAPP PAP + PGH P + V + Q + GAA PA
Sbjct: 268 AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA 316
Score = 29.3 bits (64), Expect = 3.2
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 9/61 (14%)
Query: 35 VGAAPPGAAPAPGIFSSQPGHTPHPAA--SRDPVARTSPLQTPAAPGAAAGP--ALSPVP 90
VGAA P A AP P P PAA + P +P PG AGP A VP
Sbjct: 244 VGAAAPPAPAAPS-----PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298
Query: 91 P 91
P
Sbjct: 299 P 299
Score = 29.3 bits (64), Expect = 3.2
Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 8/67 (11%)
Query: 32 AGDVGAAPPGAAPAPGIFSSQPGHTPHPA-ASRDPVARTSPLQT-------PAAPGAAAG 83
+G G AAPAPG+ + P A + +A + P T P GA
Sbjct: 326 SGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPS 385
Query: 84 PALSPVP 90
PA P P
Sbjct: 386 PAAVPPP 392
Score = 28.1 bits (61), Expect = 7.0
Identities = 27/90 (30%), Positives = 32/90 (35%), Gaps = 30/90 (33%)
Query: 32 AGDVGAAP-------PGAAPAPGIFS-SQPG----HTPHPAASRDPVARTSPLQ------ 73
AG GA P PGAAP P ++PG P P + R P+ P
Sbjct: 68 AGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLR 127
Query: 74 ------------TPAAPGAAAGPALSPVPP 91
PAA AAGP +P P
Sbjct: 128 PPPEGSAGSCAPVPAAAAVAAGPEPAPAGP 157
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 35.8 bits (81), Expect = 0.034
Identities = 21/53 (39%), Positives = 28/53 (52%), Gaps = 2/53 (3%)
Query: 38 APPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVP 90
APP AP P + + PG P A+S+ PV +P TP A+A P +P P
Sbjct: 1603 APP-LAPLP-VLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTP 1653
Score = 34.7 bits (78), Expect = 0.075
Identities = 25/68 (36%), Positives = 35/68 (51%), Gaps = 8/68 (11%)
Query: 34 DVGAAPPGAAPAPGIFSSQPGHTPH----PAASRDPVARTSPLQTPAAPGAAAGPALSPV 89
+V A+ PGAAP + S P H P PA+S P+ +SPL +P + + P S +
Sbjct: 1384 EVSASAPGAAP---LTISSPLHVPSSLPGPASSPMPIPNSSPLASPVS-STVSVPLSSSL 1439
Query: 90 PPVVHLTL 97
P V TL
Sbjct: 1440 PISVPTTL 1447
Score = 27.7 bits (60), Expect = 9.2
Identities = 15/48 (31%), Positives = 21/48 (43%)
Query: 37 AAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGP 84
A PPG++ + PG+T PAA+ T+ T A P P
Sbjct: 1119 APPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAP 1166
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 35.8 bits (81), Expect = 0.034
Identities = 20/57 (35%), Positives = 29/57 (50%), Gaps = 2/57 (3%)
Query: 38 APPGAAPAPGIFSSQPGHTP-HPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVV 93
AP GA P + S P P P++ RDP+A T+ L + P A P + +PP +
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP-ATLAPKEALIPPAM 1553
Score = 34.7 bits (78), Expect = 0.075
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 4/60 (6%)
Query: 36 GAAPPGAAPAP----GIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPP 91
GA P AA P G + P P P A P + SP TP GA+ PA +P P
Sbjct: 984 GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043
Score = 32.3 bits (72), Expect = 0.37
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 29 EWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSP 88
+W A PP +P G + P P P A+ P + P TP+ GA PA++P
Sbjct: 960 KWAPTPPAATPP--SPKGGPATPSPKGAPTPPAATPPSPKGGP-ATPSPKGAPTPPAVTP 1016
Query: 89 VPP 91
P
Sbjct: 1017 PSP 1019
Score = 31.6 bits (70), Expect = 0.64
Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 4/64 (6%)
Query: 33 GDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAG---PALSPV 89
G + P AP P + + P PA S A T P TP +P + G P +P
Sbjct: 1276 GGLATPPHKGAPNPAVVTP-PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPT 1334
Query: 90 PPVV 93
PP V
Sbjct: 1335 PPAV 1338
Score = 31.2 bits (69), Expect = 0.83
Identities = 20/53 (37%), Positives = 26/53 (49%), Gaps = 3/53 (5%)
Query: 39 PPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPP 91
PP +P G +S P P P A+ P + SP TP GA PA++P P
Sbjct: 1294 PP--SPKGGPATSPPKGAPTPPAATPPSPKGSP-GTPPPKGAPTPPAVTPPSP 1343
Score = 30.8 bits (68), Expect = 1.1
Identities = 20/68 (29%), Positives = 26/68 (38%), Gaps = 9/68 (13%)
Query: 33 GDVGAAPPGAAPAP-GIFSSQPGHTPHPAASRD--------PVARTSPLQTPAAPGAAAG 83
G G PP AP P + P TP A+ P ++ P A P G
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
Query: 84 PALSPVPP 91
PA++P P
Sbjct: 1382 PAMTPPSP 1389
Score = 30.0 bits (66), Expect = 1.8
Identities = 16/56 (28%), Positives = 22/56 (39%)
Query: 36 GAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPP 91
G A P + P + + P P A + +SP + PA P P L V P
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP 1510
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.137 0.442
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,736,099
Number of Sequences: 37866
Number of extensions: 575219
Number of successful extensions: 5866
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 118
Number of HSP's successfully gapped in prelim test: 395
Number of HSP's that attempted gapping in prelim test: 4793
Number of HSP's gapped (non-prelim): 1437
length of query: 239
length of database: 18,247,518
effective HSP length: 99
effective length of query: 140
effective length of database: 14,498,784
effective search space: 2029829760
effective search space used: 2029829760
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.