Guide to the Human Genome
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Name: MCL1 Sequence: fasta or formatted (350aa) NCBI GI: 11386165
Description:

myeloid cell leukemia sequence 1 isoform 1

Referenced in:

BCL2 Pathways, Caspases, and Programmed Cell Death

Other entries for this name:
alt prot [271aa] myeloid cell leukemia sequence 1 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.6         37           2
 C cysteine            0.6          2           1
 D aspartate           4.6         16           2
 E glutamate           8.9         31           4
 F phenylalanine       3.1         11           2
 G glycine            11.7         41           3
 H histidine           1.1          4           1
 I isoleucine          4.6         16           2
 K lysine              3.7         13           1
 L leucine            10.0         35           2
 M methionine          1.7          6           1
 N asparagine          2.6          9           2
 P proline             6.6         23           3
 Q glutamine           1.7          6           1
 R arginine            8.0         28           2
 S serine              6.0         21           1
 T threonine           5.7         20           1
 V valine              6.6         23           1
 W tryptophan          0.9          3           1
 Y tyrosine            1.4          5           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   myeloid cell leukemia sequence 1 isoform 1 
MCL1                  0.645   myeloid cell leukemia sequence 1 isoform 2 
BAX                   0.049   BCL2-associated X protein isoform alpha 
BCL2                  0.048   B-cell lymphoma protein 2 alpha isoform 
BCL2L1                0.045   BCL2-like 1 isoform 1 
BCL2A1                0.043   BCL2-related protein A1 isoform 1 
BAK1                  0.040   BCL2-antagonist/killer 1 
LOC100289713          0.037   PREDICTED: hypothetical protein XP_002348091 
BAX                   0.037   BCL2-associated X protein isoform beta 
BAX                   0.037   BCL2-associated X protein isoform sigma 
BCL2A1                0.037   BCL2-related protein A1 isoform 2 
BCL2                  0.036   B-cell lymphoma protein 2 beta isoform 
BAX                   0.034   BCL2-associated X protein isoform delta 
BOK                   0.030   BCL2-related ovarian killer 
SLC16A2               0.027   solute carrier family 16, member 2 
SHANK3                0.025   SH3 and multiple ankyrin repeat domains 3 
BCL2L2                0.025   BCL2-like 2 protein 
KIAA1522              0.024   hypothetical protein LOC57648 
MAP7D1                0.021   MAP7 domain containing 1 
ELN                   0.021   elastin isoform e precursor 
ELN                   0.021   elastin isoform d precursor 
ELN                   0.021   elastin isoform c precursor 
ELN                   0.021   elastin isoform a precursor 
BCL9                  0.019   B-cell CLL/lymphoma 9 
NOM1                  0.018   nucleolar protein with MIF4G domain 1 
LOC100293375          0.018   PREDICTED: hypothetical protein 
SPEG                  0.018   SPEG complex locus 
BCL2L10               0.018   BCL2-like 10 (apoptosis facilitator) 
PCNXL3                0.018   pecanex-like 3 
MEX3D                 0.018   ring finger and KH domain containing 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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