BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|71999131 opsin 3 [Homo sapiens] (402 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|71999131 opsin 3 [Homo sapiens] 820 0.0 gi|4506527 rhodopsin [Homo sapiens] 172 4e-43 gi|5730019 peropsin [Homo sapiens] 167 2e-41 gi|15150803 opsin 4 isoform 1 [Homo sapiens] 157 1e-38 gi|71999143 opsin 4 isoform 2 [Homo sapiens] 149 4e-36 gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo s... 147 2e-35 gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sa... 146 4e-35 gi|38678524 opsin 5 isoform 1 [Homo sapiens] 142 4e-34 gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [H... 139 3e-33 gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo ... 139 3e-33 gi|4557857 somatostatin receptor 1 [Homo sapiens] 109 5e-24 gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo s... 102 6e-22 gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 102 6e-22 gi|157426873 tachykinin receptor 2 [Homo sapiens] 101 1e-21 gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo s... 100 2e-21 gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 100 2e-21 gi|149944554 somatostatin receptor 4 [Homo sapiens] 100 3e-21 gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens] 99 7e-21 gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 99 7e-21 gi|167000885 galanin receptor 1 [Homo sapiens] 96 7e-20 gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo s... 93 4e-19 gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 93 4e-19 gi|4557859 somatostatin receptor 2 [Homo sapiens] 93 5e-19 gi|31083315 G protein-coupled receptor 45 [Homo sapiens] 91 2e-18 gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] 91 2e-18 gi|4557865 somatostatin receptor 5 [Homo sapiens] 89 9e-18 gi|32261309 G protein-coupled receptor 135 [Homo sapiens] 88 1e-17 gi|5921992 adenosine A2a receptor [Homo sapiens] 87 2e-17 gi|4501951 adenosine A2b receptor [Homo sapiens] 87 2e-17 gi|7669548 tachykinin receptor 3 [Homo sapiens] 87 3e-17 >gi|71999131 opsin 3 [Homo sapiens] Length = 402 Score = 820 bits (2117), Expect = 0.0 Identities = 402/402 (100%), Positives = 402/402 (100%) Query: 1 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNL 60 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNL Sbjct: 1 MYSGNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNL 60 Query: 61 LVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFS 120 LVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFS Sbjct: 61 LVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFS 120 Query: 121 GSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYI 180 GSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYI Sbjct: 121 GSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYI 180 Query: 181 LDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQT 240 LDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQT Sbjct: 181 LDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQT 240 Query: 241 IQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKS 300 IQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKS Sbjct: 241 IQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKS 300 Query: 301 NTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRP 360 NTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRP Sbjct: 301 NTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAKDLPAAGSEMQIRPIVMSQKDGDRP 360 Query: 361 KKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL 402 KKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL Sbjct: 361 KKKVTFNSSSIIFIITSDESLSVDDSDKTNGSKVDVIQVRPL 402 >gi|4506527 rhodopsin [Homo sapiens] Length = 348 Score = 172 bits (437), Expect = 4e-43 Identities = 94/297 (31%), Positives = 163/297 (54%), Gaps = 11/297 (3%) Query: 35 LFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFG 94 L P + LA + + +LG N L L + + ++LRTP + +L+N++++DL + L G Sbjct: 31 LAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGG 90 Query: 95 VTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSW- 153 T T + L +V+ GC +GF +L G +++ +L VLA ERY+ VV + NF + Sbjct: 91 FTSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYV-VVCKPMSNFRFG 149 Query: 154 ---AWRAITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKS--KDANDSSFVLFLFL 208 A + + W+ +LA A PL GW+RYI + C +D+ + + N+ SFV+++F+ Sbjct: 150 ENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFV 209 Query: 209 GCLVVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCW 268 +P+ +I CYG ++++++ Q + K EK++ +M +M+ FL+CW Sbjct: 210 VHFTIPMIIIFFCYGQLVFTVKEAAA----QQQESATTQKAEKEVTRMVIIMVIAFLICW 265 Query: 269 MPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLC 325 +PY + F + G P + FAKS +YNPVIY+ M ++FR +L +C Sbjct: 266 VPYASVAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTIC 322 >gi|5730019 peropsin [Homo sapiens] Length = 337 Score = 167 bits (422), Expect = 2e-41 Identities = 96/296 (32%), Positives = 158/296 (53%), Gaps = 13/296 (4%) Query: 35 LFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFG 94 +FS + +A L G++ + +N++VL ++ K++ LRTPT+ +++N++++D+ VS G Sbjct: 19 VFSQTEHNIVATYLIMAGMISIISNIIVLGIFIKYKELRTPTNAIIINLAVTDIGVSSIG 78 Query: 95 VTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRV----VHARVIN 150 + S L W + GC FG+ SI LTV+A +RY+ + V R+ Sbjct: 79 YPMSAASDLYGSWKFGYAGCQVYAGLNIFFGMASIGLLTVVAVDRYLTICLPDVGRRMTT 138 Query: 151 FSWAWRAITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGC 210 ++ I W+ L WA P++GW Y D G CT++W+ D + S+ + + Sbjct: 139 NTYIG-LILGAWINGLFWALMPIIGWASYAPDPTGATCTINWRKNDRSFVSYTMTVIAIN 197 Query: 211 LVVPLGVIAHCYGHILYSIR---MLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVC 267 +VPL V+ +CY H+ SI+ C E L +I + KM +MI FLV Sbjct: 198 FIVPLTVMFYCYYHVTLSIKHHTTSDCTESLNRDWSDQI-----DVTKMSVIMICMFLVA 252 Query: 268 WMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQL 323 W PY ++C G + P ++I++ LFAKS+T YNP IYV +KFRR++L + Sbjct: 253 WSPYSIVCLWASFGDPKKIPPPMAIIAPLFAKSSTFYNPCIYVVANKKFRRAMLAM 308 >gi|15150803 opsin 4 isoform 1 [Homo sapiens] Length = 478 Score = 157 bits (398), Expect = 1e-38 Identities = 100/328 (30%), Positives = 172/328 (52%), Gaps = 21/328 (6%) Query: 16 GGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTP 75 G A A P P + ++ GT + LL+G G+LG NL V+ + + + LRTP Sbjct: 51 GTWAAAWVPLPTVDVPDHAHYTLGT---VILLVGLTGMLG---NLTVIYTFCRSRSLRTP 104 Query: 76 THLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVL 135 ++ ++N+++SD L+S F S L W++ GC + F G+LFGI S+ TLT + Sbjct: 105 ANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALFGISSMITLTAI 164 Query: 136 AYERYIRVVHARVINFSWAWR-----AITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTV 190 A +RY+ V+ + F A + + +WLY+LAW+ P GW+ Y+ + C+ Sbjct: 165 ALDRYL-VITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAYVPEGLLTSCSW 223 Query: 191 DWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML--------RCVEDLQTIQ 242 D+ S ++ + L +PL +I +CY I +IR C + +++ Sbjct: 224 DYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTFGACKGNGESLW 283 Query: 243 VIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNT 302 + L+ E K+AK+ L+I F++ W PY + + G+ H++TP +S V + AK++ Sbjct: 284 QRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMSSVPAVIAKASA 343 Query: 303 VYNPVIYVFMIRKFRRSLLQ-LLCLRLL 329 ++NP+IY K+R ++ Q L CL +L Sbjct: 344 IHNPIIYAITHPKYRVAIAQHLPCLGVL 371 >gi|71999143 opsin 4 isoform 2 [Homo sapiens] Length = 489 Score = 149 bits (376), Expect = 4e-36 Identities = 100/339 (29%), Positives = 172/339 (50%), Gaps = 32/339 (9%) Query: 16 GGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKF------ 69 G A A P P + ++ GT + LL+G G+LG NL V+ + + Sbjct: 51 GTWAAAWVPLPTVDVPDHAHYTLGT---VILLVGLTGMLG---NLTVIYTFCRAVLRGVT 104 Query: 70 -----QRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLF 124 + LRTP ++ ++N+++SD L+S F S L W++ GC + F G+LF Sbjct: 105 VMMQSRSLRTPANMFIINLAVSDFLMSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGALF 164 Query: 125 GIVSIATLTVLAYERYIRVVHARVINFSWAWR-----AITYIWLYSLAWAGAPLLGWNRY 179 GI S+ TLT +A +RY+ V+ + F A + + +WLY+LAW+ P GW+ Y Sbjct: 165 GISSMITLTAIALDRYL-VITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAY 223 Query: 180 ILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML------- 232 + + C+ D+ S ++ + L +PL +I +CY I +IR Sbjct: 224 VPEGLLTSCSWDYMSFTPAVRAYTMLLCCFVFFLPLLIIIYCYIFIFRAIRETGRALQTF 283 Query: 233 -RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTIS 291 C + +++ + L+ E K+AK+ L+I F++ W PY + + G+ H++TP +S Sbjct: 284 GACKGNGESLWQRQRLQSECKMAKIMLLVILLFVLSWAPYSAVALVAFAGYAHVLTPYMS 343 Query: 292 IVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQ-LLCLRLL 329 V + AK++ ++NP+IY K+R ++ Q L CL +L Sbjct: 344 SVPAVIAKASAIHNPIIYAITHPKYRVAIAQHLPCLGVL 382 >gi|4502387 opsin 1 (cone pigments), short-wave-sensitive [Homo sapiens] Length = 348 Score = 147 bits (371), Expect = 2e-35 Identities = 84/287 (29%), Positives = 155/287 (54%), Gaps = 11/287 (3%) Query: 45 ALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLR 104 A +G++ L+G N +VLV ++++LR P + +LVN+S L+ +F V FV+ Sbjct: 38 AAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCN 97 Query: 105 NGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWR-AITYI-- 161 +V+ C +GF G++ G+V+ +L LA+ERYI V+ NF ++ + A+T + Sbjct: 98 GYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYI-VICKPFGNFRFSSKHALTVVLA 156 Query: 162 -WLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDA--NDSSFVLFLFLGCLVVPLGVI 218 W + + P GW+R+I + C DW + S+ FLF+ C +VPL +I Sbjct: 157 TWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLI 216 Query: 219 AHCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLV 278 Y +L +++ + Q + K E+++++M +M+ +F VC++PY + Sbjct: 217 CFSYTQLLRALKAVAA----QQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYM 272 Query: 279 VNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLC 325 VN H + + + F+KS +YNP+IY FM ++F+ +++++C Sbjct: 273 VNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVC 319 >gi|9910526 opsin 1 (cone pigments), long-wave-sensitive [Homo sapiens] Length = 364 Score = 146 bits (368), Expect = 4e-35 Identities = 91/276 (32%), Positives = 146/276 (52%), Gaps = 15/276 (5%) Query: 56 VGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCV 115 V N LVL KF++LR P + +LVN++++DL ++ T + V+ + +V CV Sbjct: 68 VFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISIVNQVSGYFVLGHPMCV 127 Query: 116 WDGFSGSLFGIVSIATLTVLAYERYIRVV----HARVINFSWAWRAITYIWLYSLAWAGA 171 +G++ SL GI + +L ++++ER++ V + R + A I + W++S W Sbjct: 128 LEGYTVSLCGITGLWSLAIISWERWLVVCKPFGNVR-FDAKLAIVGIAFSWIWSAVWTAP 186 Query: 172 PLLGWNRYILDVHGL----GCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILY 227 P+ GW+RY HGL G V S S+++ L + C ++PL +I CY + Sbjct: 187 PIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWL 244 Query: 228 SIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVT 287 +IR + Q + K EK++ +M +MIF + VCW PY G+ Sbjct: 245 AIRAVA----KQQKESESTQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAANPGYAFH 300 Query: 288 PTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQL 323 P ++ + FAKS T+YNPVIYVFM R+FR +LQL Sbjct: 301 PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQL 336 >gi|38678524 opsin 5 isoform 1 [Homo sapiens] Length = 354 Score = 142 bits (359), Expect = 4e-34 Identities = 79/271 (29%), Positives = 136/271 (50%), Gaps = 5/271 (1%) Query: 51 IGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWD 110 IG+L N VL + + ++ P ++ +N+++ DL +S+ G FT +SC + WV+ Sbjct: 43 IGILSTFGNGYVLYMSSRRKKKLRPAEIMTINLAVCDLGISVVGKPFTIISCFCHRWVFG 102 Query: 111 TVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARV---INFSWAWRAITYIWLYSLA 167 +GC W G++G FG S+ T+T ++ +RY+++ + + A+ + IW Y+ Sbjct: 103 WIGCRWYGWAGFFFGCGSLITMTAVSLDRYLKICYLSYGVWLKRKHAYICLAAIWAYASF 162 Query: 168 WAGAPLLGWNRYILDVHGLGCTVDWKSKDAN--DSSFVLFLFLGCLVVPLGVIAHCYGHI 225 W PL+G Y+ + G CT+DW A+ F+L + CL++P VI Y I Sbjct: 163 WTTMPLVGLGDYVPEPFGTSCTLDWWLAQASVGGQVFILNILFFCLLLPTAVIVFSYVKI 222 Query: 226 LYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHL 285 + ++ ++ E KL K+ L+ FL+ W+PY V+ G Sbjct: 223 IAKVKSSSKEVAHFDSRIHSSHVLEMKLTKVAMLICAGFLIAWIPYAVVSVWSAFGRPDS 282 Query: 286 VTPTISIVSYLFAKSNTVYNPVIYVFMIRKF 316 + +S+V L AKS +YNP+IY + KF Sbjct: 283 IPIQLSVVPTLLAKSAAMYNPIIYQVIDYKF 313 >gi|114687592 opsin 1 (cone pigments), medium-wave-sensitive 2 [Homo sapiens] Length = 364 Score = 139 bits (351), Expect = 3e-33 Identities = 88/279 (31%), Positives = 144/279 (51%), Gaps = 15/279 (5%) Query: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV 112 + V N LVL KF++LR P + +LVN++++DL ++ T + V+ + +V Sbjct: 65 IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHP 124 Query: 113 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVV----HARVINFSWAWRAITYIWLYSLAW 168 CV +G++ SL GI + +L ++++ER++ V + R + A I + W+++ W Sbjct: 125 MCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVR-FDAKLAIVGIAFSWIWAAVW 183 Query: 169 AGAPLLGWNRYILDVHGL----GCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGH 224 P+ GW+RY HGL G V S S+++ L + C + PL +I CY Sbjct: 184 TAPPIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQ 241 Query: 225 ILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGH 284 + +IR + Q + K EK++ +M +M+ F CW PY G+ Sbjct: 242 VWLAIRAVA----KQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGY 297 Query: 285 LVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQL 323 P ++ + FAKS T+YNPVIYVFM R+FR +LQL Sbjct: 298 PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQL 336 >gi|4503965 opsin 1 (cone pigments), medium-wave-sensitive [Homo sapiens] Length = 364 Score = 139 bits (351), Expect = 3e-33 Identities = 88/279 (31%), Positives = 144/279 (51%), Gaps = 15/279 (5%) Query: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV 112 + V N LVL KF++LR P + +LVN++++DL ++ T + V+ + +V Sbjct: 65 IASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADLAETVIASTISVVNQVYGYFVLGHP 124 Query: 113 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVV----HARVINFSWAWRAITYIWLYSLAW 168 CV +G++ SL GI + +L ++++ER++ V + R + A I + W+++ W Sbjct: 125 MCVLEGYTVSLCGITGLWSLAIISWERWMVVCKPFGNVR-FDAKLAIVGIAFSWIWAAVW 183 Query: 169 AGAPLLGWNRYILDVHGL----GCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGH 224 P+ GW+RY HGL G V S S+++ L + C + PL +I CY Sbjct: 184 TAPPIFGWSRYW--PHGLKTSCGPDVFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQ 241 Query: 225 ILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGH 284 + +IR + Q + K EK++ +M +M+ F CW PY G+ Sbjct: 242 VWLAIRAVA----KQQKESESTQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAANPGY 297 Query: 285 LVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQL 323 P ++ + FAKS T+YNPVIYVFM R+FR +LQL Sbjct: 298 PFHPLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQL 336 >gi|4557857 somatostatin receptor 1 [Homo sapiens] Length = 391 Score = 109 bits (272), Expect = 5e-24 Identities = 86/334 (25%), Positives = 159/334 (47%), Gaps = 32/334 (9%) Query: 8 GGHGYWDGGGAA-GAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLY 66 GG G GAA G E P + + G+ ++ + + L+G+ N +V+ + Sbjct: 24 GGGSRGPGAGAADGMEEPGRNASQNGTLSEGQGSAILISFIYSVVCLVGLCGNSMVIYVI 83 Query: 67 YKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGI 126 ++ +++T T++ ++N++++D L+ L V F S L W + + C ++ Sbjct: 84 LRYAKMKTATNIYILNLAIADELLML-SVPFLVTSTLLRHWPFGALLCRLVLSVDAVNMF 142 Query: 127 VSIATLTVLAYERYIRVVH------------ARVINFSWAWRAITYIWLYSLAWAGAPLL 174 SI LTVL+ +RY+ VVH A+V+N +W+ SL P++ Sbjct: 143 TSIYCLTVLSVDRYVAVVHPIKAARYRRPTVAKVVNLG--------VWVLSLLVI-LPIV 193 Query: 175 GWNRYILDVHGLGCTVDWKSKDAND--SSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML 232 ++R + G + A FVL+ FL ++P+G I CY I+ +RM+ Sbjct: 194 VFSRTAANSDGTVACNMLMPEPAQRWLVGFVLYTFLMGFLLPVGAICLCYVLIIAKMRMV 253 Query: 233 RCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISI 292 Q + + E+K+ M +++ F++CWMP+ V+ +VN T+S Sbjct: 254 ALKAGWQQRK-----RSERKITLMVMMVVMVFVICWMPFYVV--QLVNVFAEQDDATVSQ 306 Query: 293 VSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCL 326 +S + +N+ NP++Y F+ F+RS ++LCL Sbjct: 307 LSVILGYANSCANPILYGFLSDNFKRSFQRILCL 340 >gi|61744454 retinal G-protein coupled receptor isoform 2 [Homo sapiens] Length = 291 Score = 102 bits (254), Expect = 6e-22 Identities = 75/290 (25%), Positives = 123/290 (42%), Gaps = 39/290 (13%) Query: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV 112 L G+ N L + + K LRTP HLL+++++L+D +SL + S LR W + + Sbjct: 28 LSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRR-WPYGSD 86 Query: 113 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAP 172 GC GF G + + SI + +A+ RY + ++ A + ++WL S WA P Sbjct: 87 GCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALP 146 Query: 173 LLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRML 232 LLGW Y + G CT+D+ D N +SF+ + +PL + Y + Sbjct: 147 LLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLM------- 199 Query: 233 RCVEDLQTIQVIKILKYEKKLAKMCFLMI------FTFLVCWMPYIVICFLVVNGHGHLV 286 E+KL K L + T L+ W PY ++ V + Sbjct: 200 -----------------EQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADVTSI 242 Query: 287 TPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAK 336 +P + +V L AK N + Y +++C + +C P K Sbjct: 243 SPKLQMVPALIAKMVPTINAINYALG--------NEMVCRGIWQCLSPQK 284 >gi|223633971 G protein-coupled receptor 83 [Homo sapiens] Length = 423 Score = 102 bits (254), Expect = 6e-22 Identities = 78/289 (26%), Positives = 136/289 (47%), Gaps = 20/289 (6%) Query: 59 NLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDG 118 N+LV + +K QR+ + T L +VN++++D++++L FT V + + W++ C Sbjct: 89 NVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRFVNSTWIFGKGMCHVSR 148 Query: 119 FSGSLFGIVSIATLTVLAYERYIRVVH---------ARVINFSWAWRAITYIWLYSLAWA 169 F+ VS TLT +A +R+ ++H VI + W T+ +SL A Sbjct: 149 FAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVIWTMATF---FSLPHA 205 Query: 170 GAPLLGWNRYILDVHGLGCTVDW-KSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYS 228 L +Y D+ C D+ + D L F+ ++PL +I+ Y + Sbjct: 206 ICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYILPLLIISVAYARVAKK 265 Query: 229 IRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICF-LVVNGHGHLVT 287 + + + D+ T Q + + +KK KM L++ F +CW P + C+ L+++ Sbjct: 266 LWLCNMIGDVTTEQYFALRRKKKKTIKMLMLVVVLFALCWFP--LNCYVLLLSSKVIRTN 323 Query: 288 PTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAK 336 + + FA S+T YNP IY ++ FR L LL + CQRP K Sbjct: 324 NALYFAFHWFAMSSTCYNPFIYCWLNENFRIELKALLSM----CQRPPK 368 >gi|157426873 tachykinin receptor 2 [Homo sapiens] Length = 398 Score = 101 bits (252), Expect = 1e-21 Identities = 74/273 (27%), Positives = 127/273 (46%), Gaps = 10/273 (3%) Query: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV 112 L+ V N +V+ + +R+RT T+ +VN++L+DL ++ F F FV N W + Sbjct: 45 LVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIWYFGRA 104 Query: 113 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFS--WAWRAITYIWLYSLAWAG 170 C + VSI ++T +A +RY+ +VH S I IWL +LA A Sbjct: 105 FCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVALALA- 163 Query: 171 APLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLV--VPLGVIAHCYGHILYS 228 +P ++ +D C V W + + L + L+ +PL V+ Y I + Sbjct: 164 SPQCFYSTVTMDQGATKCVVAWPEDSGGKTLLLYHLVVIALIYFLPLAVMFVAYSVIGLT 223 Query: 229 IRMLRCVEDLQTIQV-IKILKYEKKLAKMCFLMIFTFLVCWMP---YIVICFLVVNGHGH 284 + R V Q ++ L+ KK K L++ TF +CW+P Y ++ + + H Sbjct: 224 L-WRRAVPGHQAHGANLRHLQAMKKFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCH 282 Query: 285 LVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFR 317 + + + A S+T+YNP+IY + +FR Sbjct: 283 KFIQQVYLALFWLAMSSTMYNPIIYCCLNHRFR 315 >gi|21361329 retinal G-protein coupled receptor isoform 1 [Homo sapiens] Length = 295 Score = 100 bits (250), Expect = 2e-21 Identities = 75/293 (25%), Positives = 123/293 (41%), Gaps = 41/293 (13%) Query: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLR---NGWVW 109 L G+ N L + + K LRTP HLL+++++L+D +SL + S LR W + Sbjct: 28 LSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRVSHRRWPY 87 Query: 110 DTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWA 169 + GC GF G + + SI + +A+ RY + ++ A + ++WL S WA Sbjct: 88 GSDGCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWA 147 Query: 170 GAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSI 229 PLLGW Y + G CT+D+ D N +SF+ + +PL + Y + Sbjct: 148 ALPLLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSYSLM---- 203 Query: 230 RMLRCVEDLQTIQVIKILKYEKKLAKMCFLMI------FTFLVCWMPYIVICFLVVNGHG 283 E+KL K L + T L+ W PY ++ V Sbjct: 204 --------------------EQKLGKSGHLQVNTTLPARTLLLGWGPYAILYLYAVIADV 243 Query: 284 HLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLLRCQRPAK 336 ++P + +V L AK N + Y +++C + +C P K Sbjct: 244 TSISPKLQMVPALIAKMVPTINAINYALG--------NEMVCRGIWQCLSPQK 288 >gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] Length = 384 Score = 100 bits (249), Expect = 2e-21 Identities = 86/295 (29%), Positives = 147/295 (49%), Gaps = 24/295 (8%) Query: 44 LALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCL 103 LAL G++ +LGV NL ++++ K + +R T++L+VN+S SDLLV++ + FTFV L Sbjct: 43 LALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVYTL 102 Query: 104 RNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHAR--VINFSWAWRAITYI 161 + WV+ C + F + VSI +L ++A ER+ +++ R N A+ I I Sbjct: 103 MDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIAVI 162 Query: 162 WLYSLAWAGAPLLGWNRYILDVHGLGCTVD-WKSK---------DANDSSFVLFLFLGCL 211 W+ ++A + P L + + + D T+D +K K D++ S+ L + Sbjct: 163 WVLAVA-SSLPFLIY-QVMTDEPFQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLVLQY 220 Query: 212 VVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKILKYE-KKLAKMCFLMIFTFLVCWMP 270 PL I CY I IR+ R + ++ K E K++ M ++ F VCW+P Sbjct: 221 FGPLCFIFICYFKIY--IRLKRRNNMMDKMRDNKYRSSETKRINIMLLSIVVAFAVCWLP 278 Query: 271 YIVICFLVVNGHGHLVTPT-----ISIVSYLFAKSNTVYNPVIYVFMIRKFRRSL 320 + F V H + T + ++ +L A +T NP+ Y F+ + F+R L Sbjct: 279 LTI--FNTVFDWNHQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLNKNFQRDL 331 >gi|149944554 somatostatin receptor 4 [Homo sapiens] Length = 388 Score = 100 bits (248), Expect = 3e-21 Identities = 85/337 (25%), Positives = 150/337 (44%), Gaps = 31/337 (9%) Query: 4 GNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVL 63 G G + A+ A A P + G + + + L+G+ N LV+ Sbjct: 11 GEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAGMVA-IQCIYALVCLVGLVGNALVI 69 Query: 64 VLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSL 123 + ++ +++T T++ L+N++++D L L V F S W + +V C L Sbjct: 70 FVILRYAKMKTATNIYLLNLAVADELFML-SVPFVASSAALRHWPFGSVLCRAVLSVDGL 128 Query: 124 FGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITY------------IWLYSL-AWAG 170 S+ LTVL+ +RY+ VVH RA TY +WL SL Sbjct: 129 NMFTSVFCLTVLSVDRYVAVVHPL--------RAATYRRPSVAKLINLGVWLASLLVTLP 180 Query: 171 APLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIR 230 + R + C + W A + FV++ FL ++P+ I CY I+ +R Sbjct: 181 IAIFADTRPARGGQAVACNLQWPHP-AWSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMR 239 Query: 231 MLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTI 290 + Q + + EKK+ ++ +++ F++CWMP+ V+ L N + T+ Sbjct: 240 AVALRAGWQQRR-----RSEKKITRLVLMVVVVFVLCWMPFYVVQLL--NLFVTSLDATV 292 Query: 291 SIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLR 327 + VS + + +N+ NP++Y F+ FRR ++LCLR Sbjct: 293 NHVSLILSYANSCANPILYGFLSDNFRRFFQRVLCLR 329 >gi|4501953 adenosine A3 receptor isoform 2 [Homo sapiens] Length = 318 Score = 99.0 bits (245), Expect = 7e-21 Identities = 83/295 (28%), Positives = 132/295 (44%), Gaps = 40/295 (13%) Query: 51 IGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLF----------GVTFTFV 100 IGL + N+LV+ + L+T T +V+++L+D+ V + G+T F Sbjct: 22 IGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFY 81 Query: 101 SCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVV----HARVINFSWAWR 156 SCL + C+ +F SI +L +A +RY+RV + RV W Sbjct: 82 SCL-------FMTCLL-----LIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWL 129 Query: 157 AITYIWLYSLAWAGAPLLGWN-----RYILDVHGLGCT-VDWKSKDANDSSFVLFLFLGC 210 A+ WL S P+ GWN Y +V L C V D V F FL Sbjct: 130 ALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDY----MVYFSFLTW 185 Query: 211 LVVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMP 270 + +PL V+ Y I Y IR + + + E K AK FL++F F + W+P Sbjct: 186 IFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLP 245 Query: 271 YIVI-CFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLL 324 +I C + NG V + + L + +N++ NP++Y + I+KF+ + L +L Sbjct: 246 LSIINCIIYFNGE---VPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLIL 297 >gi|157738685 G protein-coupled receptor 103 [Homo sapiens] Length = 431 Score = 99.0 bits (245), Expect = 7e-21 Identities = 72/308 (23%), Positives = 150/308 (48%), Gaps = 29/308 (9%) Query: 43 RLALLLGSIGL--LGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFV 100 +LAL+L + + L + N LV + + + +RT T++ + +++LSDLL++ F + T + Sbjct: 45 KLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTML 104 Query: 101 SCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSW----AWR 156 + + W+ C F S + I T+T +A ER+ +VH + + + A+ Sbjct: 105 QNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFT 164 Query: 157 AITYIWLYSLAWAGAPLLGWN--------RYILDVHGLGCTVDWKSKDANDSSFVLFLFL 208 + +WL ++ G+P+ W+ ++ + + C +W S + + F+ + Sbjct: 165 MLGVVWLVAVI-VGSPM--WHVQQLEIKYDFLYEKEHICCLEEWTS-PVHQKIYTTFILV 220 Query: 209 GCLVVPLGVIAHCYGHILYSIRMLRCVED---LQTI---QVIKILKYEKKLAKMCFLMIF 262 ++PL V+ Y I Y + + + V D L+TI ++ KI + +K+ M ++ Sbjct: 221 ILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVA 280 Query: 263 TFLVCWMPYIVICFLV-----VNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFR 317 F VCW P+ V+ ++ + + I + + SN++ NP++Y FM F+ Sbjct: 281 LFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFK 340 Query: 318 RSLLQLLC 325 +++L +C Sbjct: 341 KNVLSAVC 348 >gi|167000885 galanin receptor 1 [Homo sapiens] Length = 349 Score = 95.5 bits (236), Expect = 7e-20 Identities = 90/332 (27%), Positives = 156/332 (46%), Gaps = 32/332 (9%) Query: 4 GNRSGGHGYWDGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLL-GSIGLLGV-GNNLL 61 GN S G+ W E PAP P PLF G + L++ G I LGV GN+L+ Sbjct: 6 GNLSEGNASWP-------EPPAP----EPGPLFGIGVENFVTLVVFGLIFALGVLGNSLV 54 Query: 62 VLVLYY-KFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFS 120 + VL K + R+ T+L ++N+S++DL LF + F WV C + + Sbjct: 55 ITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYF 114 Query: 121 GSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWR----AITYIWLYSLAWAGAPLLGW 176 ++ +VSI TL ++ +RY+ +VH+R + R + IW S+A A + + Sbjct: 115 FTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASP--VAY 172 Query: 177 NRYILDVHGLGCTVDWKS--KDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRC 234 ++ + T W+ + ++V+ F+ ++PL +I CY +L + Sbjct: 173 HQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLH---- 228 Query: 235 VEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPT---IS 291 + L+ + K +KK A+ +++ F + W+P+ +I G L TP Sbjct: 229 -KKLKNMSK-KSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPL-TPASFLFR 285 Query: 292 IVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQL 323 I ++ A SN+ NP+IY F+ FR++ Q+ Sbjct: 286 ITAHCLAYSNSSVNPIIYAFLSENFRKAYKQV 317 >gi|61744452 retinal G-protein coupled receptor isoform 3 [Homo sapiens] Length = 253 Score = 93.2 bits (230), Expect = 4e-19 Identities = 53/170 (31%), Positives = 85/170 (50%), Gaps = 1/170 (0%) Query: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV 112 L G+ N L + + K LRTP HLL+++++L+D +SL + S LR W + + Sbjct: 28 LSGLSLNTLTIFSFCKTPELRTPCHLLVLSLALADSGISLNALVAATSSLLRR-WPYGSD 86 Query: 113 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITYIWLYSLAWAGAP 172 GC GF G + + SI + +A+ RY + ++ A + ++WL S WA P Sbjct: 87 GCQAHGFQGFVTALASICSSAAIAWGRYHHYCTRSQLAWNSAVSLVLFVWLSSAFWAALP 146 Query: 173 LLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCY 222 LLGW Y + G CT+D+ D N +SF+ + +PL + Y Sbjct: 147 LLGWGHYDYEPLGTCCTLDYSKGDRNFTSFLFTMSFFNFAMPLFITITSY 196 >gi|39725940 opioid receptor, kappa 1 [Homo sapiens] Length = 380 Score = 93.2 bits (230), Expect = 4e-19 Identities = 77/316 (24%), Positives = 152/316 (48%), Gaps = 24/316 (7%) Query: 14 DGGGAAGAEGPAPAGTLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLR 73 D G+AG+E L PA + SP + + + ++G+ N LV+ + ++ +++ Sbjct: 37 DSNGSAGSED----AQLEPAHI-SPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMK 91 Query: 74 TPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLT 133 T T++ + N++L+D LV+ + F L N W + V C SI TLT Sbjct: 92 TATNIYIFNLALADALVTTT-MPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLT 150 Query: 134 VLAYERYIRVVH-ARVINFSWAWRAITY---IWLYSLAWA-GAPLLGWNRYILDVHGLGC 188 +++ +RYI V H + ++F +A IWL S + A +LG + DV + C Sbjct: 151 MMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIEC 210 Query: 189 TVDWKSKDAN--DSSFVLFLFLGCLVVPLGVIAHCYGHILYSIRMLRCVEDLQTIQVIKI 246 ++ + D + D + +F+ V+P+ +I CY ++ ++ +R + + Sbjct: 211 SLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKD---- 266 Query: 247 LKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLF----AKSNT 302 + +++ ++ +++ F+VCW P + F++V G T ++ SY F +N+ Sbjct: 267 -RNLRRITRLVLVVVAVFVVCWTP--IHIFILVEALGSTSHSTAALSSYYFCIALGYTNS 323 Query: 303 VYNPVIYVFMIRKFRR 318 NP++Y F+ F+R Sbjct: 324 SLNPILYAFLDENFKR 339 >gi|4557859 somatostatin receptor 2 [Homo sapiens] Length = 369 Score = 92.8 bits (229), Expect = 5e-19 Identities = 68/292 (23%), Positives = 137/292 (46%), Gaps = 35/292 (11%) Query: 53 LLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTV 112 ++G+ N LV+ + ++ +++T T++ ++N++++D L L G+ F + W + Sbjct: 55 IIGLCGNTLVIYVILRYAKMKTITNIYILNLAIADELFML-GLPFLAMQVALVHWPFGKA 113 Query: 113 GCVWDGFSGSLFGIVSIATLTVLAYERYIRVVH------------ARVINFSWAWRAITY 160 C + SI LTV++ +RY+ VVH A++I + W Sbjct: 114 ICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMA-VWGVSLL 172 Query: 161 IWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKD-ANDSSFVLFLFLGCLVVPLGVIA 219 + L + +AG W R CT++W + A + F+++ F+ +VPL +I Sbjct: 173 VILPIMIYAGLRSNQWGRS-------SCTINWPGESGAWYTGFIIYTFILGFLVPLTIIC 225 Query: 220 HCYGHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVV 279 CY I+ ++ + K K EKK+ +M +++ F+ CW+P+ + V Sbjct: 226 LCYLFIIIKVKSSGI-----RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYI---FNV 277 Query: 280 NGHGHLVTPTISIVS-----YLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCL 326 + ++PT ++ + +N+ NP++Y F+ F++S +LCL Sbjct: 278 SSVSMAISPTPALKGMFDFVVVLTYANSCANPILYAFLSDNFKKSFQNVLCL 329 >gi|31083315 G protein-coupled receptor 45 [Homo sapiens] Length = 372 Score = 90.9 bits (224), Expect = 2e-18 Identities = 82/325 (25%), Positives = 145/325 (44%), Gaps = 41/325 (12%) Query: 29 TLSPAPLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDL 88 T PAPL + + LL+ +G LG N +V ++ Y+ +R+ +LLL ++ SD+ Sbjct: 27 TQLPAPLRI--SLAIVMLLMTVVGFLG---NTVVCIIVYQRPAMRSAINLLLATLAFSDI 81 Query: 89 LVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHAR- 147 ++SL + FT V+ + W + C F + +A L +++ +R++ +V + Sbjct: 82 MLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQD 141 Query: 148 VINFSWAWRAITYIWLYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLF 207 +N A I W+ S AG L GW + C + + A D ++V+ L Sbjct: 142 KLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPA-DRAYVVTLV 200 Query: 208 LGCLVVPLGVIAHCYGHILYSIRM---------------------LRCVEDLQTIQVIKI 246 + P GV+ Y IL ++R LR ++ Q + V Sbjct: 201 VAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSV--D 258 Query: 247 LKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVV------NGHGHLVTPTISI-VSYLFAK 299 L ++ K ++ F +CW+P+ V L V G T T + +SYL Sbjct: 259 LSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYL--- 315 Query: 300 SNTVYNPVIYVFMIRKFRRSLLQLL 324 +V+NP++Y + I+KFR + ++LL Sbjct: 316 -KSVFNPIVYCWRIKKFREACIELL 339 >gi|24476016 G protein-coupled receptor 161 isoform 2 [Homo sapiens] Length = 529 Score = 90.5 bits (223), Expect = 2e-18 Identities = 77/299 (25%), Positives = 129/299 (43%), Gaps = 43/299 (14%) Query: 59 NLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDG 118 NL+++V YK L T ++ + +++LS+ L+S+ + F S +R W++ G VW Sbjct: 45 NLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIF---GVVWCN 101 Query: 119 FSGSLFGIVSIA---TLTVLAYERYIRVVHARV----INFSWAWRAITYIWLYSLAWAGA 171 FS L+ ++S A TL V+A +RY V++ V I + A A+ YIWL+SL Sbjct: 102 FSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLP 161 Query: 172 PLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHIL----Y 227 PL GW+ D C W + + F + C + P V+ CYG I Sbjct: 162 PLFGWSSVEFDEFKWMCVAAWH----REPGYTAFWQIWCALFPFLVMLVCYGFIFRVARV 217 Query: 228 SIRMLRC------VEDLQ-------------------TIQVIKILKYEKKLAKMCFLMIF 262 R + C ED Q Q + + K +++ Sbjct: 218 KARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVYSANQCKALITILVVLG 277 Query: 263 TFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLL 321 F+V W PY+V+ V+P++ + + ++ V +P+IY + R+ LL Sbjct: 278 AFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIYGLWNKTVRKELL 336 >gi|4557865 somatostatin receptor 5 [Homo sapiens] Length = 364 Score = 88.6 bits (218), Expect = 9e-18 Identities = 90/331 (27%), Positives = 148/331 (44%), Gaps = 36/331 (10%) Query: 13 WDGGGAAGAEGPAPAGTL-SPAPLFSPGTYERLA-LLLGSIGLLGVGNNLLVLVLYYKFQ 70 W+ A G TL PAP S G L +L + G+G N LV+ + +F Sbjct: 12 WNASSPGAASGGGDNRTLVGPAP--SAGARAVLVPVLYLLVCAAGLGGNTLVIYVVLRFA 69 Query: 71 RLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIA 130 +++T T++ ++N++++D+L L G+ F + W + V C + S+ Sbjct: 70 KMKTVTNIYILNLAVADVLYML-GLPFLATQNAASFWPFGPVLCRLVMTLDGVNQFTSVF 128 Query: 131 TLTVLAYERYIRVVH----ARVINFSWAWRAITYIWLYSLAWAGAPLLGWNRYILDV-HG 185 LTV++ +RY+ VVH AR A A W+ SL + PLL DV G Sbjct: 129 CLTVMSVDRYLAVVHPLSSARWRRPRVAKLASAAAWVLSLCMS-LPLL----VFADVQEG 183 Query: 186 LGCTVDW-KSKDANDSSFVLFLFLGCLVVPLGVIAHCYGHILYSIR----MLRCVEDLQT 240 C W + + F+++ + PL VI CY I+ +R + CV Sbjct: 184 GTCNASWPEPVGLWGAVFIIYTAVLGFFAPLLVICLCYLLIVVKVRAAGVRVGCVR---- 239 Query: 241 IQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGHLVTPTISIVSYLF--- 297 + E+K+ +M +++ F CW+P+ + +VN L S Y F Sbjct: 240 ------RRSERKVTRMVLVVVLVFAGCWLPFFTV--NIVNLAVALPQEPASAGLYFFVVI 291 Query: 298 -AKSNTVYNPVIYVFMIRKFRRSLLQLLCLR 327 + +N+ NPV+Y F+ FR+S ++LCLR Sbjct: 292 LSYANSCANPVLYGFLSDNFRQSFQKVLCLR 322 >gi|32261309 G protein-coupled receptor 135 [Homo sapiens] Length = 494 Score = 88.2 bits (217), Expect = 1e-17 Identities = 94/326 (28%), Positives = 142/326 (43%), Gaps = 31/326 (9%) Query: 9 GHGYWDGGGAAGAEGPAPAGTLSP--APLFSPGT-YERLALLLGSIGLLGVGNNLLVLVL 65 G G G GAA G A L P APL S G AL+L I LL N V+ + Sbjct: 68 GGGGLGGSGAAREAGAAVRRPLGPEAAPLLSHGAAVAAQALVLLLIFLLSSLGNCAVMGV 127 Query: 66 YYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLR--NGWVWDTVGCVWDGFS--- 120 K ++LRT T+ ++++SLSDLL +L + F+ G W GF Sbjct: 128 IVKHRQLRTVTNAFILSLSLSDLLTALLCLPAAFLDLFTPPGGSAPAAAAGPWRGFCAAS 187 Query: 121 ---GSLFGIVSIATLTVLAYERYIRVVH--ARVINFSWAWRAITYIWL----YSLAWAGA 171 S FGIVS ++ +++ +RY +V I A + + WL +SL W Sbjct: 188 RFFSSCFGIVSTLSVALISLDRYCAIVRPPREKIGRRRALQLLAGAWLTALGFSLPW--- 244 Query: 172 PLLGWNRYILDVHGL-GCTVDWKSKDAN-DSSFVLFLFLGCLVVPLGVIAHCYGHILYSI 229 LLG R + GC A ++F + L + C ++P ++ C+ HI ++ Sbjct: 245 ELLGAPRELAAAQSFHGCLYRTSPDPAQLGAAFSVGLVVACYLLPFLLMCFCHYHICKTV 304 Query: 230 RMLRC-VEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVVNGHGH---- 284 R+ V + T + E + A +MI + CW PY CFLV+ Sbjct: 305 RLSDVRVRPVNTYARVLRFFSEVRTATTVLIMIVFVICCWGPY---CFLVLLAAARQAQT 361 Query: 285 LVTPT-ISIVSYLFAKSNTVYNPVIY 309 + P+ +S+V+ +N NPVIY Sbjct: 362 MQAPSLLSVVAVWLTWANGAINPVIY 387 >gi|5921992 adenosine A2a receptor [Homo sapiens] Length = 412 Score = 87.4 bits (215), Expect = 2e-17 Identities = 84/330 (25%), Positives = 150/330 (45%), Gaps = 24/330 (7%) Query: 34 PLFSPGTYERLALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLF 93 P+ Y + L + + +LG N+LV + L+ T+ +V+++ +D+ V + Sbjct: 2 PIMGSSVYITVELAIAVLAILG---NVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVL 58 Query: 94 GVTFTFVSCLRNGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRV-VHARVINFS 152 + F + G+ GC++ + SI +L +A +RYI + + R Sbjct: 59 AIPFAIT--ISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLV 116 Query: 153 WAWRA---ITYIWLYSLAWAGAPLLGWNRYILDV----HGLGC---TVDWKSKDANDSSF 202 RA I W+ S A P+LGWN H GC V +D ++ Sbjct: 117 TGTRAKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNY 176 Query: 203 -VLFLFLGCLVVPLGVIAHCYGHI-LYSIRMLRCVED--LQTIQVIKILKYEKKLAKMCF 258 V F F C++VPL ++ Y I L + R L+ +E L + L+ E AK Sbjct: 177 MVYFNFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLA 236 Query: 259 LMIFTFLVCWMP-YIVICFLVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFR 317 +++ F +CW+P +I+ CF + ++ + + +N+V NP IY + IR+FR Sbjct: 237 IIVGLFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFR 296 Query: 318 RSLLQLLCLRLLRCQRPAKDLPAAGSEMQI 347 ++ +++ +LR Q P K AAG+ ++ Sbjct: 297 QTFRKIIRSHVLRQQEPFK---AAGTSARV 323 >gi|4501951 adenosine A2b receptor [Homo sapiens] Length = 332 Score = 87.4 bits (215), Expect = 2e-17 Identities = 80/307 (26%), Positives = 132/307 (42%), Gaps = 28/307 (9%) Query: 51 IGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLRNGWVWD 110 I L V N+LV L+TPT+ LV+++ +D+ V LF + F L G+ D Sbjct: 17 IAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISL--GFCTD 74 Query: 111 TVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVV----HARVINFSWAWRAITYIWLYSL 166 GC++ + SI +L +A +RY+ + + ++ + A I +W+ + Sbjct: 75 FYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAF 134 Query: 167 AWAGAPLLGWNRYILDVHGLGCTVDWKSKDAND--------------SSFVLFLFLGCLV 212 P LGWN D CT W S V F F GC++ Sbjct: 135 GIGLTPFLGWNS--KDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVL 192 Query: 213 VPLGVIAHCYGHI-LYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMP- 270 PL ++ Y I L + R L+ E + + L+ E AK +++ F +CW+P Sbjct: 193 PPLLIMLVIYIKIFLVACRQLQRTELMDHSRT--TLQREIHAAKSLAMIVGIFALCWLPV 250 Query: 271 YIVICF-LVVNGHGHLVTPTISIVSYLFAKSNTVYNPVIYVFMIRKFRRSLLQLLCLRLL 329 + V C L G ++ L + +N+V NP++Y + R FR + +++ R L Sbjct: 251 HAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIIS-RYL 309 Query: 330 RCQRPAK 336 CQ K Sbjct: 310 LCQADVK 316 >gi|7669548 tachykinin receptor 3 [Homo sapiens] Length = 465 Score = 87.0 bits (214), Expect = 3e-17 Identities = 69/282 (24%), Positives = 126/282 (44%), Gaps = 15/282 (5%) Query: 45 ALLLGSIGLLGVGNNLLVLVLYYKFQRLRTPTHLLLVNISLSDLLVSLFGVTFTFVSCLR 104 +L G + + V NL+V+ + +R+RT T+ LVN++ SD ++ F F+ L Sbjct: 89 SLAYGVVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALH 148 Query: 105 NGWVWDTVGCVWDGFSGSLFGIVSIATLTVLAYERYIRVVHARVINFSWAWRAITY--IW 162 + W + C + F SI ++T +A +RY+ ++ S I IW Sbjct: 149 SEWYFGANYCRFQNFFPITAVFASIYSMTAIAVDRYMAIIDPLKPRLSATATKIVIGSIW 208 Query: 163 LYSLAWAGAPLLGWNRYILDVHGLGCTVDWKSKDANDSSFVLFLFLGCLVVPLGVIAHCY 222 + + A L ++ L C V W ++ + + + PL ++ Y Sbjct: 209 ILAFLLAFPQCLYSKTKVMPGRTL-CFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITY 267 Query: 223 ---GHILYSIRMLRCVEDLQTIQVIKILKYEKKLAKMCFLMIFTFLVCWMPYIVICFLVV 279 G L+ + D Q LK ++K+ KM +++ TF +CW+PY I F++ Sbjct: 268 TIVGITLWGGEIPGDTCDKYHEQ----LKAKRKVVKMMIIVVMTFAICWLPY-HIYFILT 322 Query: 280 NGHGHL----VTPTISIVSYLFAKSNTVYNPVIYVFMIRKFR 317 + L + + S+ A S+T+YNP+IY + ++FR Sbjct: 323 AIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFR 364 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.328 0.143 0.458 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,419,825 Number of Sequences: 37866 Number of extensions: 697533 Number of successful extensions: 5429 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 295 Number of HSP's successfully gapped in prelim test: 352 Number of HSP's that attempted gapping in prelim test: 4281 Number of HSP's gapped (non-prelim): 843 length of query: 402 length of database: 18,247,518 effective HSP length: 105 effective length of query: 297 effective length of database: 14,271,588 effective search space: 4238661636 effective search space used: 4238661636 T: 11 A: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.