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Search of human proteins with 71725360
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71725360 zinc finger protein 609 [Homo sapiens]
(1411 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71725360 zinc finger protein 609 [Homo sapiens] 2844 0.0
gi|153945755 zinc finger protein 608 [Homo sapiens] 1004 0.0
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 64 1e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 61 9e-09
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 60 2e-08
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 58 7e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 57 1e-07
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 57 1e-07
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 57 1e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 55 4e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 55 4e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 55 6e-07
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 53 2e-06
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 52 4e-06
gi|104526627 triadin [Homo sapiens] 52 4e-06
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 51 7e-06
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 50 1e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 49 3e-05
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 49 3e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 47 1e-04
gi|150378539 piccolo isoform 1 [Homo sapiens] 47 1e-04
gi|91982772 mucin 17 [Homo sapiens] 47 2e-04
gi|55750053 atrophin-1 [Homo sapiens] 46 3e-04
gi|55750041 atrophin-1 [Homo sapiens] 46 3e-04
gi|40288197 GATA binding protein 6 [Homo sapiens] 45 4e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 45 6e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 44 8e-04
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 44 0.001
gi|169166609 PREDICTED: similar to ribonucleic acid binding prot... 43 0.002
gi|113415994 PREDICTED: similar to ribonucleic acid binding prot... 43 0.002
>gi|71725360 zinc finger protein 609 [Homo sapiens]
Length = 1411
Score = 2844 bits (7373), Expect = 0.0
Identities = 1411/1411 (100%), Positives = 1411/1411 (100%)
Query: 1 MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIP 60
MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIP
Sbjct: 1 MSLSSGASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIP 60
Query: 61 APNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKE 120
APNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKE
Sbjct: 61 APNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKE 120
Query: 121 VQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSE 180
VQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSE
Sbjct: 121 VQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSE 180
Query: 181 KDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECR 240
KDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECR
Sbjct: 181 KDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECR 240
Query: 241 LLKKVKSEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEP 300
LLKKVKSEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEP
Sbjct: 241 LLKKVKSEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEP 300
Query: 301 ECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPT 360
ECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPT
Sbjct: 301 ECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPT 360
Query: 361 SDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHR 420
SDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHR
Sbjct: 361 SDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHR 420
Query: 421 PPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKV 480
PPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKV
Sbjct: 421 PPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKV 480
Query: 481 EPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPI 540
EPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPI
Sbjct: 481 EPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPI 540
Query: 541 LHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTD 600
LHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTD
Sbjct: 541 LHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTD 600
Query: 601 LGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIA 660
LGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIA
Sbjct: 601 LGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIA 660
Query: 661 PAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPA 720
PAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPA
Sbjct: 661 PAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPA 720
Query: 721 LTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDP 780
LTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDP
Sbjct: 721 LTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDP 780
Query: 781 HQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKT 840
HQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKT
Sbjct: 781 HQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKT 840
Query: 841 NSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYS 900
NSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYS
Sbjct: 841 NSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYS 900
Query: 901 PSYAQSSPGALNPSSQAGVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSV 960
PSYAQSSPGALNPSSQAGVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSV
Sbjct: 901 PSYAQSSPGALNPSSQAGVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSV 960
Query: 961 IQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRG 1020
IQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRG
Sbjct: 961 IQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRG 1020
Query: 1021 VDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVII 1080
VDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVII
Sbjct: 1021 VDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVII 1080
Query: 1081 PKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRM 1140
PKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRM
Sbjct: 1081 PKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRM 1140
Query: 1141 WTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESR 1200
WTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESR
Sbjct: 1141 WTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESR 1200
Query: 1201 LGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYL 1260
LGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYL
Sbjct: 1201 LGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYL 1260
Query: 1261 PSSYSFSPYGSKVSGGEDADKARASPSVTCKSSSESKALDILQQHASHYKSKSPTISDKT 1320
PSSYSFSPYGSKVSGGEDADKARASPSVTCKSSSESKALDILQQHASHYKSKSPTISDKT
Sbjct: 1261 PSSYSFSPYGSKVSGGEDADKARASPSVTCKSSSESKALDILQQHASHYKSKSPTISDKT 1320
Query: 1321 SQERDRGGCGVVGGGGSCSSVGGASGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQ 1380
SQERDRGGCGVVGGGGSCSSVGGASGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQ
Sbjct: 1321 SQERDRGGCGVVGGGGSCSSVGGASGGERSVDRPRTSPSQRLMSTHHHHHHLGYSLLPAQ 1380
Query: 1381 YNLPYAAGLSSTAIVASQQGSTPSLYPPPRR 1411
YNLPYAAGLSSTAIVASQQGSTPSLYPPPRR
Sbjct: 1381 YNLPYAAGLSSTAIVASQQGSTPSLYPPPRR 1411
>gi|153945755 zinc finger protein 608 [Homo sapiens]
Length = 1512
Score = 1004 bits (2596), Expect = 0.0
Identities = 670/1572 (42%), Positives = 897/1572 (57%), Gaps = 233/1572 (14%)
Query: 7 ASGGKGVDANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEM---------SGSKEV 57
++ GKGVD N V+TYDSGD+W+IGVGNLIIDLDADLEKD+QK EM S SK+
Sbjct: 6 STAGKGVDPNTVDTYDSGDDWEIGVGNLIIDLDADLEKDRQKFEMNNSTTTTSSSNSKDC 65
Query: 58 GIPAPN---AVATLPDNIKFVT-PVPGPQGKE----GKSKSKRSKSGKDTSKPTPGTSLF 109
G PA + A A L D +KF + PQG KSK KRSK+ KD +K P +L+
Sbjct: 66 GGPASSGAGATAALADGLKFASVQASAPQGNSHKETSKSKVKRSKTSKDANKSLPSAALY 125
Query: 110 TPSE--GAASKKEVQGRSGDGANAGGLVAAIAPKG------------SEKAAKASRSVAG 155
E ++EVQGR G+ + G S AA A G
Sbjct: 126 GIPEISSTGKRQEVQGRPGEATGMNSALGQSVSSGGSGNPNSNSTSTSTSAATAGAGSCG 185
Query: 156 SKKEKENSSSKSKK--ERSEGVGTCSEKDPGVLQ--------PVPLGGR----GGQYDGS 201
KE++ S+S + +R + G + +LQ P GG G + +G
Sbjct: 186 KSKEEKPGKSQSSRGAKRDKDAGKSRKDKHDLLQGHQNGSGSQAPSGGHLYGFGAKSNGG 245
Query: 202 A-------GVDTGAVEPLGSI---AIEPGAALNPLGTKPEPEEGENECRLLKKVKSEKME 251
G +G+V G + A + G N + K E EE E+ R +KK+K+EK++
Sbjct: 246 GASPFHCGGTGSGSVAAAGEVSKSAPDSGLMGNSMLVKKEEEEEESH-RRIKKLKTEKVD 304
Query: 252 S---------PVS---TPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATE 299
P+S TP +LP + +++I++P EQ++VRTRSVGVNTC+V + TE
Sbjct: 305 PLFTVPAPPPPISSSLTPQILPSYFSPS--SSNIAAPVEQLLVRTRSVGVNTCEVGVVTE 362
Query: 300 PECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSP 359
PECLGPCEPGTSVNLEGIVW ETE+G+LVVNVTWRNKTYVGTLLDCT+HDWAPPRFC+SP
Sbjct: 363 PECLGPCEPGTSVNLEGIVWHETEEGVLVVNVTWRNKTYVGTLLDCTKHDWAPPRFCESP 422
Query: 360 TSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEH 419
TSDLEMR GRGRGKR R + P +E A+ ++S+G N K R GAN KGRRGS N+S
Sbjct: 423 TSDLEMRGGRGRGKRARSAAAAPGSE-ASFTESRGLQN--KNRGGANGKGRRGSLNASGR 479
Query: 420 RPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTK 479
R P + +ED+KASPSS NKRKNKP +++LNSSSED+K KRVRTNS + T P K
Sbjct: 480 RTPPNCAAEDIKASPSSTNKRKNKPPMELDLNSSSEDNKPGKRVRTNSRSTPT--TPQGK 537
Query: 480 VEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEP 539
E T LD+ C SPVLIDCPHPNCNKKYKHINGL+YHQAHAH D ++K E + DSE +
Sbjct: 538 PETTFLDQGCSSPVLIDCPHPNCNKKYKHINGLRYHQAHAHLDPENKLEFEPDSE---DK 594
Query: 540 ILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDT 599
I + G N A + P+ S + +L P SP + T ++ +S +
Sbjct: 595 ISDCEEGLSNVALECSE----PSTSVSAYDQLKAPASPGAGNPPGTPKGKRELMSNGPGS 650
Query: 600 DLGALSNDGSDDGPSVMDETSN--------DAFDS--------------------LERKC 631
+GA + S + +E +N A DS +++K
Sbjct: 651 IIGAKAGKNSGKKKGLNNELNNLPVISNMTAALDSCSAADGSLAAEMPKLEAEGLIDKKN 710
Query: 632 M-EKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQ--QIYTFQTATFTAASPGSSSGL- 687
+ +KEK KK ++ K +K SK LKSARPIAPA P Q+ TATFT + G+ GL
Sbjct: 711 LGDKEKGKKATNCKTDKNLSK-LKSARPIAPAPAPTPPQLIAIPTATFTTTTTGTIPGLP 769
Query: 688 --TATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKK--KESSKELES 743
T TV QA P SP LKPIQPKPT+MGEP TVNPAL KDKKKK+K+K + KE S
Sbjct: 770 SLTTTVVQATPKSPPLKPIQPKPTIMGEPITVNPALVSLKDKKKKEKRKLKDKEGKETGS 829
Query: 744 PLTPGKVCRAEEGKSPFRESSGDGMK-----MEGLLNGSSDPHQSRLASIKAEADKIYSF 798
P K+ + E+ K ++ G +K EGL NG S+ +SR+ASIKAEADK+Y+F
Sbjct: 830 PKMDAKLGKLEDSKGASKDLPGHFLKDHLNKNEGLANGLSESQESRMASIKAEADKVYTF 889
Query: 799 TDNAPSPSIGGSSRLENTTPTQ---PLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDG 855
TDNAPSPSIG +SRLE +T P+ PLHV+TQNGAE+S+ KT+SPAYSDISDA +DG
Sbjct: 890 TDNAPSPSIGSASRLECSTLVNGQAPMAPLHVLTQNGAESSAAKTSSPAYSDISDAADDG 949
Query: 856 --EGKVDSVKSKDA---------EQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYA 904
+ + + ++SK + + +VK + T Q + SPYY ++ YYSPSY
Sbjct: 950 GSDSRSEGMRSKASSPSDIISSKDSVVKGHSSTTAQSSQLKESHSPYYHSYDPYYSPSYM 1009
Query: 905 QSSPGALN-PSSQAGVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQP---SV 960
PG + P++ +Q +K K++ E E E K K + + KK + +S+S QP SV
Sbjct: 1010 H--PGQVGAPAAGNSGSTQGMKIKKESE-EDAEKKDKAEQLDSKKVDHNSASLQPQHQSV 1066
Query: 961 IQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQ-- 1018
I QR QSLYY QYAY Y DQ L++T+ AYRQQYE+ + Q L +Q+
Sbjct: 1067 ITQRHPALAQSLYYGQYAYGL---YMDQK---SLMATSPAYRQQYEKYYEDQRLAEQKMA 1120
Query: 1019 ---RG-VDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTD-------LVKSGPGKA 1067
RG ++K+E+ LKE KEE KQK T++KAPS + L S P K
Sbjct: 1121 QTGRGDCERKSELPLKELG---KEETKQKNMPSATISKAPSTPEPNKNHSKLGPSVPNKT 1177
Query: 1068 KEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMD 1127
+E G KS ++ S+ + K K + L KEA E K+ + +Q +D
Sbjct: 1178 EETG----KSQLL-----SNHQQQLQADSFKAKQMENHQLIKEAVEMKSVMDSMKQTGVD 1228
Query: 1128 PILWYRQEAEPRMWT-YVYPAKYSDIKSEDERWKEERDRKLKEERSRS----KDSVP--- 1179
P ++Q+ + R W YVY KY D + +E +R++KLKE+ R + VP
Sbjct: 1229 PTSRFKQDPDSRTWHHYVYQPKYLDQQKSEEL---DREKKLKEDSPRKTPNKESGVPSLP 1285
Query: 1180 ------KEDGKESTSSDCKLPTSEESRLGSKEPRPSVH--------VPVSSPLTQHQSYI 1225
KE+ KE+ D + + EES+L + + + V+ V VSSP++QHQSYI
Sbjct: 1286 VSLTSIKEEPKEAKHPDSQ--SMEESKLKNDDRKTPVNWKDSRGTRVAVSSPMSQHQSYI 1343
Query: 1226 PYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARAS 1285
Y+H Y Y Q YDP+HP+YR++ V+M +YPG+YL + + YG K+SG E+ +K S
Sbjct: 1344 QYLHAYPYPQMYDPSHPAYRAVSPVLMHSYPGAYLSPGFHYPVYG-KMSGREETEKVNTS 1402
Query: 1286 PSVTCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVVGGGGSCSSVGGAS 1345
PSV K+++ESKALD+LQQHA+ Y+SKSP +K + ER+R
Sbjct: 1403 PSVNTKTTTESKALDLLQQHANQYRSKSPAPVEKATAERER------------------- 1443
Query: 1346 GGERSVDRPRTSP-SQRLMSTHHHHH-HLGYSLLPAQYNLPYAAGLSSTAIVASQ----Q 1399
E +R R SP QR + THHH H +GY L+P QY+ P+ GL+S A+VASQ Q
Sbjct: 1444 --EAERERDRHSPFGQRHLHTHHHTHVGMGYPLIPGQYD-PF-QGLTSAALVASQQVAAQ 1499
Query: 1400 GSTPSLYPPPRR 1411
S ++P RR
Sbjct: 1500 ASASGMFPGQRR 1511
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 63.5 bits (153), Expect = 1e-09
Identities = 120/549 (21%), Positives = 209/549 (38%), Gaps = 72/549 (13%)
Query: 712 GEPFTVNP----ALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDG 767
GE T +P A +P K+ K K++ +S E +SP EE KSP S +
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSP-------EKEEAKSPAEVKSPEK 549
Query: 768 MKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPS-IGGSSRLENTTPTQPLTPLH 826
K S P +A++ + A SP+ S E +P + +P+
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 827 VVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQS 886
++ AEA S E+ + + + A+ KE AK P + +S
Sbjct: 610 EEAKSPAEAK------------SPVKEEAKSPAEVKSPEKAKSPTKEEAKS---PEKAKS 654
Query: 887 KDSPYYQGFESYYSP--SYAQSSPGALNPSSQAGVESQALKTKRDEEPESIEGKVKNDIC 944
+ + E SP + A+S A +P + K+ EE +S E K K+ +
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPE-KAKSPVK 713
Query: 945 EE-KKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQ 1003
EE K PE + S V ++ + A P S + T + + A
Sbjct: 714 EEAKSPEKAKS----PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP 769
Query: 1004 QYEE--------QQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPS 1055
EE +K +S +++ +KA+ LKE A ++E +K + + +
Sbjct: 770 AKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEK 829
Query: 1056 LTDL-VKSGPGKAKEPGAD----------------PAKSVIIPKLDDSSKLPGQAPEGLK 1098
++ VK P KA+E A P K PK+++ + + P+ K
Sbjct: 830 PQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889
Query: 1099 VKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDER 1158
V+ KE +E K + E + +++A+P+ T V + D K+++
Sbjct: 890 VE------AKKEEAEDKKKVPT-PEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS 942
Query: 1159 WKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESRLGSKEP-RPSVHVPVSSP 1217
E+ E++ ++ K + K T + K E+ + SKEP +P S
Sbjct: 943 KPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAK----EDDKTLSKEPSKPKAEKAEKSS 998
Query: 1218 LTQHQSYIP 1226
T + P
Sbjct: 999 STDQKDSKP 1007
Score = 54.7 bits (130), Expect = 6e-07
Identities = 98/448 (21%), Positives = 174/448 (38%), Gaps = 44/448 (9%)
Query: 516 QAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGA-SVSQKGSLSPARSATPKVRLVEP 574
+A + +++K A+ S EE A++ S A S +++ + SP + +P+ E
Sbjct: 515 EAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKE--EA 572
Query: 575 HSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEK 634
SP+ K K K + + A + V +E + A E K K
Sbjct: 573 KSPA-----EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA----EAKSPVK 623
Query: 635 EKCKKPSSLK-PEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQ 693
E+ K P+ +K PEK S + + A+ A P++ + A SP + + A+
Sbjct: 624 EEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEA--KSPEKAKSPVKAEAKSPEKAK 681
Query: 694 AMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRA 753
+ + P + K V E + A +P K++ K +K K KE K
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVK 741
Query: 754 EEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRL 813
EE KSP + S + K + L S + ++ ADK F + A SP +
Sbjct: 742 EEAKSPEKAKSPE--KAKTLDVKSPEAKTPAKEEARSPADK---FPEKAKSP-----VKE 791
Query: 814 ENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKE 873
E +P + +PL +A + + P ++ ++ E K VK K+ + +E
Sbjct: 792 EVKSPEKAKSPLK------EDAKAPEKEIPKKEEVKSPVKE-EEKPQEVKVKEPPKKAEE 844
Query: 874 GAKKTLFPPQPQSKDSPYYQG---------FESYYSPSYAQSSPGALNPSSQAGVESQAL 924
K P + KDS + E P+ + + + + + +
Sbjct: 845 -EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903
Query: 925 KTKRDEEPESIEGKVKNDICEEKKPELS 952
T E P +E VK D ++K E++
Sbjct: 904 PTPEKEAPAKVE--VKEDAKPKEKTEVA 929
Score = 39.7 bits (91), Expect = 0.021
Identities = 57/233 (24%), Positives = 100/233 (42%), Gaps = 31/233 (13%)
Query: 1003 QQYEEQQKRQSLEQQQRGVDKKAEMGLKE------REAALKEEWKQKP----SIPPTLTK 1052
++ E++ K + ++++ G +++AE G +E EAA E+ + P + P K
Sbjct: 472 EEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAK 531
Query: 1053 APSLTDL-----VKSGPGKAKEPGADPAKSVIIPKL--DDSSKLPGQAPEGLKVKLSDAS 1105
+P + VKS P KAK P + AKS K + +K P + K K S A
Sbjct: 532 SPEKEEAKSPAEVKS-PEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAK-SPAK 589
Query: 1106 HLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDR 1165
+K +EAK+ + + + + AE + P K + KS E E+ +
Sbjct: 590 EEAKSPAEAKSPEKAKSPVKEEA----KSPAEAKS-----PVK-EEAKSPAEVKSPEKAK 639
Query: 1166 KLKEERSRSKDSVPKEDGKESTSSD-CKLPTSEESRLGSKEPRPSVHVPVSSP 1217
+E ++S + + +E+ S + K P E++ K P V SP
Sbjct: 640 SPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSP-VKAEAKSP 691
Score = 34.7 bits (78), Expect = 0.67
Identities = 53/254 (20%), Positives = 97/254 (38%), Gaps = 38/254 (14%)
Query: 1089 LPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAK 1148
+P PEGL S ++H+ ++ E E ++E + ++ Q E ++
Sbjct: 418 IPFSLPEGLPKIPSVSTHIKVKSEEKIKVVE---KSEKETVIVEEQTEETQV-------- 466
Query: 1149 YSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESRLGSKEPRP 1208
E EE +++ KEE + ++ +E+ E + K P +EE+ KE +
Sbjct: 467 -------TEEVTEEEEKEAKEEEGKEEEGGEEEEA-EGGEEETKSPPAEEAASPEKEAKS 518
Query: 1209 SVHVPVSSPL----TQHQSYIPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYLPSSY 1264
V SP + + S ++ P +S P + P+
Sbjct: 519 PVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEV 578
Query: 1265 SFSPYGSKVSGGEDA---------DKARASPSVTCKSSSESKA-----LDILQQHASHYK 1310
SP +K E+A +KA++ KS +E+K+ + S K
Sbjct: 579 K-SPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEK 637
Query: 1311 SKSPTISDKTSQER 1324
+KSPT + S E+
Sbjct: 638 AKSPTKEEAKSPEK 651
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 60.8 bits (146), Expect = 9e-09
Identities = 129/645 (20%), Positives = 233/645 (36%), Gaps = 88/645 (13%)
Query: 366 RNGRGRGK----RMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRP 421
R+GR R + R R S TP S+ S + R+ + + RRG SS R
Sbjct: 677 RSGRSRSRTPARRGRSRSRTP-----RRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERK 731
Query: 422 PASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVE 481
S TS+ S SS +K++ S + SS SK R+ S + P P K +
Sbjct: 732 NKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQ 791
Query: 482 -PTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPI 540
P R+ S P + + P S P
Sbjct: 792 TPPRRSRSGSSQPKAKSRTPPRRSRSS--------SSPPPKQKSKTPSRQSHSSSSPHPK 843
Query: 541 LHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTD 600
+ + G+ S + + +S TP+ R SP P K T + SG
Sbjct: 844 VKSGTPPRQGSITSPQAN---EQSVTPQRRSCFESSPDPELKSRTPS--RHSCSGSSPPR 898
Query: 601 LGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIP--SKSLKSARP 658
+ + + S + A S ++ PS + P S+S+
Sbjct: 899 VKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 659 IAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVN 718
+ + P+ ++ GSSS T + P I P P V +
Sbjct: 959 VESRLLPRYSHS-----------GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQT-PPG 1006
Query: 719 PALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRES--SGDGMKMEGLLNG 776
P+L+ +K ++K K + L+ +C + +P ES ++++G
Sbjct: 1007 PSLSGSKSPCPQEKSKDSLVQSCPGSLS---LCAGVKSSTPPGESYFGVSSLQLKGQSQT 1063
Query: 777 SSDPHQSRLASIK-----AEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQN 831
S D H+S +S + +E+ + S + +P GG SR +++P L + Q+
Sbjct: 1064 SPD-HRSDTSSPEVRQSHSESPSLQSKSQTSPK---GGRSR--SSSPVTELASRSPIRQD 1117
Query: 832 --------------GAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKK 877
E S +++S +Y + G+ ++++ +SK+ L +
Sbjct: 1118 RGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQ-EDA 1176
Query: 878 TLFPPQPQSKDSPY---------YQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKR 928
T PP+ + K SP+ ++ +P +S G+ S + ++ AL T
Sbjct: 1177 TASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGS---SPETKEQNSALPTSS 1233
Query: 929 DEE--------PESIEGKVKNDICEEKKPELSSSSQQPSVIQQRP 965
+E E G++ + + E K +S+ + +++RP
Sbjct: 1234 QDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERP 1278
Score = 42.7 bits (99), Expect = 0.002
Identities = 46/211 (21%), Positives = 83/211 (39%), Gaps = 9/211 (4%)
Query: 381 TPV--NETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSAN 438
TPV +++ ++ T++S+ G S G +S PPAS+ ++ A +
Sbjct: 2467 TPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQP 2526
Query: 439 KRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTK--VEPTVLDRNCPSPVLID 496
++ + S +SSS S S ++S GS++ G+ V+P V + PSP
Sbjct: 2527 AKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAP 2586
Query: 497 CPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQK 556
+ + + ++ + + S + S + S + +S S
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 557 GSLSPAR---SATPKVRLVEPHSPSPSSKFS 584
S SPA+ A PK P P P + S
Sbjct: 2647 SSPSPAKPGPQALPKP--ASPKKPPPGERRS 2675
Score = 42.4 bits (98), Expect = 0.003
Identities = 40/154 (25%), Positives = 70/154 (45%), Gaps = 25/154 (16%)
Query: 358 SPTSDLEMRNGRGRGKRMRPNSNTPVNETA---TASDSKGTSNSSKTR------------ 402
SPT + ++ + KR R + P + A T++DS +S++S++R
Sbjct: 231 SPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTA 290
Query: 403 -AGAN---SKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSK 458
AG + + GRRG ++ P +ST +SP +A K+ + P D + + K
Sbjct: 291 LAGRSPSPASGRRGEGDAPFSEPGTTSTQR--PSSPETATKQPSSPYEDKD---KDKKEK 345
Query: 459 GSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSP 492
+ R + S+TGP P P + +R+ SP
Sbjct: 346 SATRPSPSPERSSTGPEPPAPT-PLLAERHGGSP 378
Score = 37.0 bits (84), Expect = 0.13
Identities = 34/146 (23%), Positives = 60/146 (41%), Gaps = 17/146 (11%)
Query: 1066 KAKEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAE 1125
+AK+P +P K + + SS+ P + K K D S+ +S + + ++ +
Sbjct: 159 EAKQPAPEPPKPYSLVRESSSSRSP-TPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217
Query: 1126 MDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKE 1185
+R E+E + + P S KS+D+ K +RSRS PK
Sbjct: 218 ------HRSESESKKRKHRSPTPKSKRKSKDK----------KRKRSRSTTPAPKSRRAH 261
Query: 1186 STSSDCKLPTSEESRLGSKEPRPSVH 1211
++S +S+ SR S+ H
Sbjct: 262 RSTSADSASSSDTSRSRSRSAAAKTH 287
Score = 36.6 bits (83), Expect = 0.18
Identities = 78/392 (19%), Positives = 133/392 (33%), Gaps = 55/392 (14%)
Query: 130 NAGGLVAAIAPKGSEKAAKASRSVAGSK--------KEKENSSSKSKKERSEGVG-TCSE 180
++G + ++P EKA +S S +E SSS S E +G+ T S
Sbjct: 1378 SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSR 1437
Query: 181 KDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECR 240
+ P G R G S +G+ + I P + + PEP +
Sbjct: 1438 RSRSGSSP---GLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP-------K 1487
Query: 241 LLKKVKSEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEP 300
L + + SP S P +NN +P R RS ++ D
Sbjct: 1488 ALPQTPRPRSRSPSS-----------PELNNKCLTP-----QRERSGSESSVDQKTVART 1531
Query: 301 ECLGPCEPGTSVNL---------EGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWA 351
G+S L E + D R ++ G+ +
Sbjct: 1532 PLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRL 1591
Query: 352 PPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDS---KGTSNSSKTRAGANSK 408
PR S +S E+++ R + S++ A A + + S SS G + +
Sbjct: 1592 SPRRSRSGSSP-EVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650
Query: 409 GRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSM 468
G +++S EH P + + ++SP K + P SS + +++ R +
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP----RRRSSRSSPELTRKARLSRR 1706
Query: 469 GSATGPLPGTKVEPTVLDRNCPSPVLIDCPHP 500
+ P T+ R PS + P P
Sbjct: 1707 SRSASSSPETRSRTPPRHRRSPS---VSSPEP 1735
Score = 34.7 bits (78), Expect = 0.67
Identities = 76/425 (17%), Positives = 146/425 (34%), Gaps = 37/425 (8%)
Query: 388 TASDSKGTSNSSKTRAGANSKGRRGSQ----------NSSEHRPPASSTSEDVKASPSSA 437
TA++ +S + + A AN G R + ++ PAS TS + + S A
Sbjct: 2319 TAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGA 2378
Query: 438 NKRKNK-PLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLID 496
N + PLS E S R R+ + SA + + PSP
Sbjct: 2379 NLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPS-------QSRMTSERAPSPSSRM 2431
Query: 497 CPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQK 556
P+ + + + A +D A G + + + + ++
Sbjct: 2432 GQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHN 2491
Query: 557 GSLSPARSATPKVRLVEPHSPS----PSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDG 612
G LS P + EP + + PS+ + + +++ S + + S+ S
Sbjct: 2492 GMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS 2551
Query: 613 PSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAP---------AI 663
S +S+ + + K+ S P P ++++ RP P +
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPS--PTPAPKEAVREGRPPEPTPAKRKRRSSS 2609
Query: 664 PPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTP 723
+ +++ +++S SSS +++ + + +S P KP P +P P
Sbjct: 2610 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPP 2669
Query: 724 AKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPF----RESSGDGMKMEGLLNGSSD 779
+++ + +K S L+ V R P + SS + G S
Sbjct: 2670 PGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRS 2729
Query: 780 PHQSR 784
P R
Sbjct: 2730 PSHKR 2734
Score = 33.5 bits (75), Expect = 1.5
Identities = 60/239 (25%), Positives = 84/239 (35%), Gaps = 51/239 (21%)
Query: 722 TPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPH 781
TP +K KDKK+K S +P + + R +S D SSD
Sbjct: 233 TPKSKRKSKDKKRKRSRSTTPAP----------KSRRAHRSTSADSA-------SSSDTS 275
Query: 782 QSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTN 841
+SR S A+ + +PSP+ G R E P + E ++ + +
Sbjct: 276 RSRSRSAAAKTHTT-ALAGRSPSPASG--RRGEGDAPFSEPGTTSTQRPSSPETATKQPS 332
Query: 842 SPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSP 901
SP Y D + K KS E + PP P + + G SP
Sbjct: 333 SP-YED--------KDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGG-----SP 378
Query: 902 SYAQSSPGALNPSSQAGVE--SQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQP 958
P A P SQ V S+A T+ P+S EK P+ SSS P
Sbjct: 379 -----QPLATTPLSQEPVNPPSEASPTRDRSPPKS----------PEKLPQSSSSESSP 422
Score = 32.7 bits (73), Expect = 2.5
Identities = 67/344 (19%), Positives = 113/344 (32%), Gaps = 86/344 (25%)
Query: 373 KRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNS-------SEHRPPASS 425
K+ P P + +S S+ + K + +GRR +S S + S
Sbjct: 161 KQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRS 220
Query: 426 TSEDVKA---SPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGP-------- 474
SE K SP+ +KRK+K S++ K + R+ S SA+
Sbjct: 221 ESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR 280
Query: 475 LPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSE 534
K T L PSP S +GD+
Sbjct: 281 SAAAKTHTTALAGRSPSPA-------------------------------SGRRGEGDAP 309
Query: 535 YGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLS 594
+ S+ G+ S R ++P E + PSS + K KK+ S
Sbjct: 310 F------------------SEPGTTSTQRPSSP-----ETATKQPSSPYEDKDKDKKEKS 346
Query: 595 GEGDTDLGALSNDGSD-DGPS-VMDETSNDAFDSLERKCMEKEKCKKPSSL--------- 643
+ S+ G + P+ ++ E + L + +E PS
Sbjct: 347 ATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPP 406
Query: 644 -KPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSG 686
PEK+P S + P P+ P ++ +++ + P + G
Sbjct: 407 KSPEKLPQSSSSESSP--PSPQPTKVSRHASSSPESPKPAPAPG 448
Score = 30.8 bits (68), Expect = 9.6
Identities = 29/147 (19%), Positives = 47/147 (31%), Gaps = 12/147 (8%)
Query: 56 EVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGA 115
+VG P + A P + + P + S S S S +S + +S + S+
Sbjct: 2505 DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 116 ASKKEVQGRSG------------DGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENS 163
S VQ + G K +++ +S S + S +S
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 164 SSKSKKERSEGVGTCSEKDPGVLQPVP 190
SS S S + S P P
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSP 2651
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 59.7 bits (143), Expect = 2e-08
Identities = 247/1295 (19%), Positives = 420/1295 (32%), Gaps = 177/1295 (13%)
Query: 14 DANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKL---EMSGSKEVGIPAPNAVATLPD 70
D++ +T S DE D+ V K +K+ + + G P A P
Sbjct: 197 DSSSEDTSSSSDETDVEV------------KASEKILQVRAASAPAKGTPGKGATPAPPG 244
Query: 71 NIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGAN 130
V GK + S+ D+ + TP ++ + +V S
Sbjct: 245 KAGAVASQT-KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE 303
Query: 131 AGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQPVP 190
+ AA AP G A A A + K +E+S S S++ SE K G V
Sbjct: 304 SPRKGAAPAPPGKTGPAVAK---AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
Query: 191 LGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVKSEKM 250
+ G G A + ++ EE +++ L + + ++
Sbjct: 361 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
Query: 251 ESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGT 310
+ +P V P + + P V V AT +G E +
Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGP------------VPPGKVGPATPSAQVGKWEEDS 468
Query: 311 SVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDC---TRHDWAPPRFCDSPTSDLEMRN 367
+ E ++ DG + V + +G +L + PP+ ++
Sbjct: 469 ESSSEES--SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 526
Query: 368 GRGRGKRMRPNSNTPVNETA----TASDSKGTSNSSKTRAGANSKGRRGSQNSSEHR--- 420
+ +S++ +E A TA+ +K +T+A S + R
Sbjct: 527 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 586
Query: 421 --PPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGT 478
P + T+ S + +P D +S DS+ K ++G A G
Sbjct: 587 QAPRKAGTATSPAGSSPAVAGGTQRPAEDSS-SSEESDSEEEKTGLAVTVGQAKSVGKGL 645
Query: 479 KVEPTVLD-----RNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDS 533
+V+ + +PVL P + +A D +S E
Sbjct: 646 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV----------KAEKQEDSESSEEESDSE 695
Query: 534 EYGEEPI--------LHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPS------- 578
E P A + S KG++S + SPS
Sbjct: 696 EAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVR 755
Query: 579 --PSSKFSTKGLCKKKLSGEG-DTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKE 635
+S +G G+ T A + D G S + S + ++L + +
Sbjct: 756 NPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGK 815
Query: 636 KCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSG-LTATVAQA 694
+ ++L P K + + P P Q + +++ S G A V A
Sbjct: 816 THQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSA 875
Query: 695 MPNSPQLKPIQPKPTVMG---EPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVC 751
P L + P + G P A TP K + + + SS+ + + P C
Sbjct: 876 QVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQC 935
Query: 752 ----------------------RAEEGKSPFRESS--GDGMKMEGLLNGSSDPHQSRL-- 785
+ G S +ESS DG K EG S + + L
Sbjct: 936 LTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPL 995
Query: 786 --ASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLT-PLHVVTQNGAEASSVKTNS 842
A++K A K + P SS +++ T P T P Q K
Sbjct: 996 TQAALKVLAQK--ASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKL 1053
Query: 843 PAYSDISDAGE---DGEGKVDSVKSKDAEQLVKEGAKK--TLFPPQPQS-----KDSPYY 892
P + A E D E DS + + +GAK TL P P +++
Sbjct: 1054 PEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAE 1113
Query: 893 QGFESYYSPSYAQSSPGALNPS-SQAGVESQALKTKRDEEP---ESIEGKVKNDICEEKK 948
+ +PS + S G + P + A ++ K D P ++ K D +E K
Sbjct: 1114 SSEDDVVAPSQSLLS-GYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAK 1172
Query: 949 PELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLST----------- 997
P+ ++ P + S Q + P G + T L +
Sbjct: 1173 PQQAAGMLSP----KTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPW 1228
Query: 998 --NTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPS 1055
N A Q + + LEQ++ KK KE E K+K S + P
Sbjct: 1229 PLNEAQVQASVVKVLTELLEQER----KKVVDTTKESSRKGWESRKRKLSGDQPAARTPR 1284
Query: 1056 LTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAK 1115
K G G+ E P K+ S+ G+A S + E K
Sbjct: 1285 SKKKKKLGAGEGGEASVSPEKT--------STTSKGKAKR---------DKASGDVKEKK 1327
Query: 1116 TGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSK 1175
G Q D +E + M T V S+ KS+ E+ K ++ +K KE++ +
Sbjct: 1328 GKGSLGSQGAKDE---PEEELQKGMGT-VEGGDQSNPKSKKEKKKSDKRKKDKEKKEK-- 1381
Query: 1176 DSVPKEDGKESTSSDCKLPTSEESRLGSKEPRPSV 1210
K+ K++++ D + P+ ++ + K +V
Sbjct: 1382 ----KKKAKKASTKDSESPSQKKKKKKKKTAEQTV 1412
Score = 36.6 bits (83), Expect = 0.18
Identities = 77/393 (19%), Positives = 136/393 (34%), Gaps = 50/393 (12%)
Query: 571 LVEPHSPSPSSKFSTKGLCKKKLSGEGDTD-LGALSNDGSDDGPSVMDETSNDAFDSLER 629
L+ SP S++ S + EG GA + G D +S D S +
Sbjct: 151 LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQA-DSSSEDTSSSSDE 209
Query: 630 KCMEKEKCKKPSSLKPEKIPSKSL--KSARPIAPAIPPQQIYTFQTATFTAASPGSSSGL 687
+E + +K ++ P+K K A P PP + + T S
Sbjct: 210 TDVEVKASEKILQVRAASAPAKGTPGKGATPA----PPGKAGAVASQTKAGKPEEDSESS 265
Query: 688 TATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTP 747
+ + + +P K + + G+ V A PAK+ +K +P P
Sbjct: 266 SEESSDSEEETPAAKALL-QAKASGKTSQVGAASAPAKESPRKGA----------APAPP 314
Query: 748 GK----VCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAP 803
GK V +A+ GK RE E SD + A K +
Sbjct: 315 GKTGPAVAKAQAGK---REEDSQSSSEE------SDSEEEAPAQAKP----------SGK 355
Query: 804 SPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVK 863
+P + +S +P + P + G A+ V+ D + E+ + +++
Sbjct: 356 APQVRAASAPAKESPRKGAAPAPP-RKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALA 413
Query: 864 SKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQA 923
+ +A Q VK K P P +G + G PS+Q G +
Sbjct: 414 AMNAAQ-VKPLGKSPQVKPASTMGMGPLGKG-----AGPVPPGKVGPATPSAQVGKWEED 467
Query: 924 LKTKRDEEPESIEGKVKNDICEEKKPELSSSSQ 956
++ +E +S +G+V + ++ L + Q
Sbjct: 468 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ 500
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 57.8 bits (138), Expect = 7e-08
Identities = 117/560 (20%), Positives = 190/560 (33%), Gaps = 82/560 (14%)
Query: 789 KAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVV------TQNGAEASSVKTNS 842
+A+ D S TD+AP + S + +P PL+P+H TQ ++ NS
Sbjct: 180 RADGDHCASVTDSAPEREL--SPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNS 237
Query: 843 PAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPS 902
Y + D +D+ + +T PP SK Q +Y P
Sbjct: 238 KGYCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPM 297
Query: 903 YAQSSPGALNPS---------------SQAGVESQALKTKRDEEPESIEGKVKNDI--CE 945
Q + +P + V ++A TK +S+E N++ E
Sbjct: 298 DGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVE 357
Query: 946 EKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQY 1005
E E++ S P P+ S + P+ D + +S+ T ++QY
Sbjct: 358 EILKEMTHSWPPPLTAIHTPSTAEPSKF--------PFPTKDSQH----VSSVTQNQKQY 405
Query: 1006 EEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPG 1065
+ K S QQ + ++ L + E + E Q P PP+ + P S P
Sbjct: 406 DTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSE---QTPEKPPSSSAPP-------SAPQ 455
Query: 1066 KAKEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAE 1125
EP A S S++ S+++ S +S++++ + E
Sbjct: 456 SLPEPVASAHSS--------SAE-------------SESTSDSDSSSDSESESSSSDSEE 494
Query: 1126 MDPILWYRQEAEP---RMWTY-VYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKE 1181
+P+ E EP W + K S + E + + E S DS +
Sbjct: 495 NEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEPPRRHPESKGSSDSATSQ 554
Query: 1182 DGKESTSSDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNH 1241
+ ES K +S+ R + P P SP Q P Q P
Sbjct: 555 EHSESKDPPPK-SSSKAPRAPPEAPHPGKRSCQKSPAQQEP---PQRQTVGTKQPKKPVK 610
Query: 1242 PSYRSMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASPSVTCKSSSESKALDI 1301
S R+ +Q G P PYGS+ +D K + +S+E K
Sbjct: 611 ASARAGSRTSLQ---GEREP---GLLPYGSRDQTSKDKPKVKTKGRPRAAASNEPKPAVP 664
Query: 1302 LQQHASHYKSKSPTISDKTS 1321
+KS P S S
Sbjct: 665 PSSEKKKHKSSLPAPSKALS 684
Score = 43.5 bits (101), Expect = 0.001
Identities = 126/607 (20%), Positives = 209/607 (34%), Gaps = 91/607 (14%)
Query: 329 VNVTWRNKTY-VGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETA 387
V T+ N+ + V +L H W PP S E K + S+ N+
Sbjct: 345 VEQTYSNEVHCVEEILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQ 404
Query: 388 TASDSKGTSNSSKTRAGAN------SKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRK 441
+ SK SNS + + S + +PP+SS S
Sbjct: 405 YDTSSKTHSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASA 464
Query: 442 NKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPL--PGTKVEPTVLDR------------ 487
+ ++ E S S+ S S+ ++S PL P + EP ++
Sbjct: 465 HSSSAESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQ 524
Query: 488 -NCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLG 546
P P + + K + Q H+ + D P++ + H
Sbjct: 525 PAAPPEGPRSTEPPRRHPESKGSSDSATSQEHSESKDPP-PKSSSKAPRAPPEAPHPGKR 583
Query: 547 SCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDL--GAL 604
SC QK SPA+ P+ + V P K S + + L GE + L
Sbjct: 584 SC------QK---SPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGS 634
Query: 605 SNDGSDDGPSVMDETSNDAFDSLERKCM---EKEKCKKPSSLKPEKIPSKSLKSARPIAP 661
+ S D P V + A S E K EK K SSL PSK+L P
Sbjct: 635 RDQTSKDKPKVKTKGRPRAAASNEPKPAVPPSSEKKKHKSSL---PAPSKALSGPEPAKD 691
Query: 662 AIPPQQIYTFQTATFTAAS--PGSSSG------LTATVAQ----------AMPNSPQLKP 703
+ + F T + P S SG A V Q + ++ L P
Sbjct: 692 NVEDRTPEHFALVPLTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSP 751
Query: 704 IQ--PKPTVMGEPFTVN-------PALTPAKDKKKKDKKK---KESSKELESPLTPGKVC 751
++ P P + T++ P ++ +K +DK+ K+ S E S + K+
Sbjct: 752 LRDTPPPQSLMVKITLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLA 811
Query: 752 RAEEGKSPFRESSGDGMKMEGLL----NGSSDPHQSRLASIKAEADKIYSFTDNAPSPSI 807
+ +G++ R+ +++E + + SS H+ + + S + P P +
Sbjct: 812 KKRKGEAE-RDCDNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPV 870
Query: 808 GGSSRLENTTPTQPLTPLHVVTQNGAE---------ASSVKTNSPAYSDISDAGEDGEGK 858
SS+ +P P ++ A+ ASS K+N S +G+G
Sbjct: 871 SSSSQ-------KPAKPALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGS 923
Query: 859 VDSVKSK 865
S + K
Sbjct: 924 RSSSEHK 930
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 57.4 bits (137), Expect = 1e-07
Identities = 111/625 (17%), Positives = 209/625 (33%), Gaps = 36/625 (5%)
Query: 358 SPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSN----------SSKTRAGANS 407
S SD NG G + + ++ SDS G N S K ++ ++
Sbjct: 492 SYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSD 551
Query: 408 KGRRGSQNSSEHRPPA------SSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSK 461
S NSS+ + S++S D +S S ++ + SD +S S DS S
Sbjct: 552 SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611
Query: 462 RVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHT 521
++S S+ +K E D + S D N + + + + +
Sbjct: 612 D-SSDSSDSSDSKSDSSKSESDSSDSDSKS----DSSDSNSSDSSDNSDSSDSSNSSNSS 666
Query: 522 D-----DDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHS 576
D D S + DS + +D + + +S S S S + ++ S
Sbjct: 667 DSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDS 726
Query: 577 PSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEK 636
S +S S+ S D+ + S+D SD S S+D+ DS +
Sbjct: 727 DSSNSSDSSD---SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 637 CKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMP 696
SS + S + + + + ++ + +S S S ++ + +
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Query: 697 NSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEG 756
+S + + + + + D S E + + +
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDS 903
Query: 757 KSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENT 816
S +S D + SSD +S +S + + + +D++ S SS N+
Sbjct: 904 DSSDSSNSSDSSDS----SNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNS 959
Query: 817 TPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGE--DGEGKVDSVKSKDAEQLVKEG 874
+ + + + + SS ++S SD SD+ + D DS S D+
Sbjct: 960 SDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 875 AKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKRDEEPES 934
S S +S S + SS + N S + + + + +S
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS-NSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 935 IEGKVKNDICEEKKPELSSSSQQPS 959
+ +D + SS S S
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSS 1103
Score = 48.5 bits (114), Expect = 4e-05
Identities = 57/269 (21%), Positives = 104/269 (38%), Gaps = 2/269 (0%)
Query: 358 SPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSS 417
S +SD + R ++++ ++++ +S+S +S+SS + +NS S NSS
Sbjct: 842 SDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS 901
Query: 418 EHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPG 477
+ SS S D S +S++ ++ SD +S S +S S +S S +
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSD 961
Query: 478 TKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGE 537
+ D N S D + + + + +++ D S DS
Sbjct: 962 SSNSSDSSDSN--SSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSS 1019
Query: 538 EPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEG 597
+ +D + + +S S S S S + S S S S+ S
Sbjct: 1020 DSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1079
Query: 598 DTDLGALSNDGSDDGPSVMDETSNDAFDS 626
D+ + S+D S+ S S+D+ DS
Sbjct: 1080 DSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108
Score = 47.8 bits (112), Expect = 8e-05
Identities = 105/605 (17%), Positives = 208/605 (34%), Gaps = 13/605 (2%)
Query: 357 DSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNS 416
DS +SD + + NS+ ++++ +SDS +S+SS +++ +SK S +S
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDS-SDSSDSSDSSDSSDSSDSKSD-SSKSESDSSDS 636
Query: 417 SEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLP 476
+ S S D + S++ + SD +S S DS S +NS S+
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD-SSNSSDSSDSSDS 695
Query: 477 GTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYG 536
E + + S N N + +++ D S +S
Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755
Query: 537 EEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGE 596
+ ++ + +S S S S S + S S +S S+ S
Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Query: 597 GDTDL--GALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLK 654
D+D + S++ SD S S+D+ DS + + + SS + S
Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSN-RSDSSNSSDSSDSSDSS 874
Query: 655 SARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEP 714
++ + + + ++ ++ S S S ++ + + +S + +
Sbjct: 875 NSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSN 934
Query: 715 FTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLL 774
+ + + + D S+ S + + + S
Sbjct: 935 SSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDS 994
Query: 775 NGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAE 834
+ SSD S +S +++ + +D++ S SS +++ + + + +
Sbjct: 995 SDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSS-----DSSDSS 1049
Query: 835 ASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQG 894
SS +NS SD SD+ + + DS S D+ + S S
Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108
Query: 895 FESYYSPSYAQSSPGALNPSSQAGVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSS 954
+S S + SS + + S +S D +S E +D + SS
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSS-DSSESSDSSDSSDSSDSSDSSD 1167
Query: 955 SQQPS 959
S S
Sbjct: 1168 SSDSS 1172
Score = 47.4 bits (111), Expect = 1e-04
Identities = 107/583 (18%), Positives = 200/583 (34%), Gaps = 25/583 (4%)
Query: 357 DSPTSDLEMRNGRGRGKRMRPNSN--TPVNETATASDSKGTSNSSKTRAGANSKGRRGSQ 414
DS +SD + NS+ + + ++ +SDS +SNSS + ++S S
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 415 NSSEHRPPA-SSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATG 473
+SS+ + SS S D S +S++ + SD +S S DS S ++S S+
Sbjct: 769 DSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS--DSDSSNSSDS 826
Query: 474 PLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDS 533
+ + + S D + + + N + + D S DS
Sbjct: 827 SNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS----SDSSDSSDSSNSSDSSDS 882
Query: 534 EYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKL 593
E +D + +S S S + ++ S S S S+
Sbjct: 883 SDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS----SNSSDSSESSNSSDNSNSSDS 938
Query: 594 SGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSL 653
S D+ + S++ SD S S+D+ DS + S S S
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSS 998
Query: 654 KSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGE 713
S+ + + ++ + +S S+S ++ + + +S +
Sbjct: 999 DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSS 1058
Query: 714 PFTVNPALTPAKDK--KKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKME 771
+ + + + D ESS +S + ++ S S D
Sbjct: 1059 DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS 1118
Query: 772 GLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQN 831
N SSD S +S +++ +D++ S SS +++ + +
Sbjct: 1119 DSSN-SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSS--------DSS 1169
Query: 832 GAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPY 891
+ SS +NS SD SD+ + + DS S D+ S S
Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 892 YQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKRDEEPES 934
ES S + SS + + S +S + ++E +S
Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDS 1271
Score = 37.7 bits (86), Expect = 0.079
Identities = 145/853 (16%), Positives = 252/853 (29%), Gaps = 44/853 (5%)
Query: 522 DDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPH------ 575
+DD+ E+D +S + ++D NG KG+ +T + +
Sbjct: 474 NDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNG 533
Query: 576 SPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPS---------VMDETSNDAFDS 626
+ S KG S D+ + S+D SD S D S+D+ DS
Sbjct: 534 NDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDS 593
Query: 627 LERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSG 686
S S S S + + ++ + + S SS
Sbjct: 594 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDN 653
Query: 687 LTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLT 746
++ + NS + N + + + +SS +S +
Sbjct: 654 SDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Query: 747 PGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPS 806
+S D + SSD S +S +++ + +D++ S
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSN-SSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSD 772
Query: 807 IGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGE-DGEGKVDSVKSK 865
SS N++ + + + + + SS +NS SD SD+ + D DS S
Sbjct: 773 SSDSSDSSNSSDSNDSS--NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830
Query: 866 DAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALK 925
D+ + + DS +S S + SS + + S +S
Sbjct: 831 DSSD-SSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESS 889
Query: 926 TKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGY 985
D S +D + SS S S + N S +
Sbjct: 890 NSSDSSDSS--NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDS 947
Query: 986 SDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPS 1045
SD S + +++ + D + + S
Sbjct: 948 SDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSS 1007
Query: 1046 IPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDAS 1105
+ + + +D S +D + S DSS + SD+S
Sbjct: 1008 DSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSS 1067
Query: 1106 HLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDR 1165
S ++S++ ++ ++ + S S+ + D
Sbjct: 1068 D-SSDSSDSSDSSDSSESSDSS------------------DSSNSSDSSDSSDSSDSSDS 1108
Query: 1166 KLKEERSRSKDSVPKEDGKEST-SSDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSY 1224
+ S S DS D +S+ SSD ++ S E S SS +
Sbjct: 1109 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDS 1168
Query: 1225 IPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARA 1284
S S D + S S + + S S S + +D + +
Sbjct: 1169 SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1228
Query: 1285 SPSVTCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVVGGGGSCSSVGGA 1344
S S SS+S D S S S SD TS D G G+ +
Sbjct: 1229 SDSNESSDSSDSS--DSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSD 1286
Query: 1345 SGGERSVDRPRTS 1357
S E S TS
Sbjct: 1287 SDSEGSDSNHSTS 1299
Score = 31.2 bits (69), Expect = 7.4
Identities = 20/74 (27%), Positives = 37/74 (50%), Gaps = 5/74 (6%)
Query: 384 NETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNK 443
++++ +SDS +S+S+++ ++S S NSS+ SS S D S S +N +
Sbjct: 1217 SDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSD-----SSDSSDSSDSTSDSNDESDS 1271
Query: 444 PLSDMELNSSSEDS 457
N++ DS
Sbjct: 1272 QSKSGNGNNNGSDS 1285
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 57.4 bits (137), Expect = 1e-07
Identities = 250/1297 (19%), Positives = 434/1297 (33%), Gaps = 195/1297 (15%)
Query: 14 DANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEV----GIPAPNAVATLP 69
D++ +T S DE D+ + ++ Q K +KE PAP V +
Sbjct: 197 DSSSEDTSSSSDETDV-------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
Query: 70 DNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGA 129
+K P + K+ + +S+ S+ G ++ + P T S+ AS+K +Q R+
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG---TRSQVKASEKILQVRAASAP 306
Query: 130 NAG--GLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQ 187
G G A AP G + A AS++ AG +E SSS+ + E L
Sbjct: 307 AKGTPGKGATPAPPG-KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAK-----ALL 360
Query: 188 PVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVKS 247
G+ Q G+A G+ PG P K + + E + + +
Sbjct: 361 QAKASGKTSQV-GAASAPAKESPRKGAAPAPPGKT-GPAVAKAQAGKREEDSQSSSEESD 418
Query: 248 EKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCE 307
+ E+P S Q+ + + A P GP
Sbjct: 419 SEEEAPAQAKP---------------SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
Query: 308 PGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDC-TRHDWAPPRFCDSPTSDLEMR 366
V ++ ED + ++ + + + P+ P S + M
Sbjct: 464 AQVQVG------KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV--KPASTMGMG 515
Query: 367 N-GRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGR----------RGSQN 415
G+G G + P P +A + S SS + +S G + N
Sbjct: 516 PLGKGAGP-VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGN 574
Query: 416 SSEHRPPAS-STSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGP 474
+ +P +S + KA P + + KP+ + E + S DS S+ + P
Sbjct: 575 ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKP 634
Query: 475 ---LPGTKVEPTVLDRNCPS---PVLIDCPHPNCNKKYKHINGLKYHQAHA--HTDDDSK 526
+P TK P + + PV + P G A +DS
Sbjct: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
Query: 527 PEADGDSEYGEEPILHADLGSCNG---------ASVSQKGSLSPARSAT------PKVRL 571
+ DSE E+ L +G ASV KGSL + P V
Sbjct: 695 SSEESDSEE-EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
Query: 572 VEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLER-- 629
V+ S + ++ + + + ++ + +
Sbjct: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV 813
Query: 630 KCMEKEKCKKPSSLKPE-KIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLT 688
+ K + PS +KP + P S AR PA P TA P SG +
Sbjct: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLAR--GPASVPSVGKAVATAAQAQTGPEEDSGSS 871
Query: 689 ATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPG 748
+ + + L ++P G+ + AL PAK+ +K K S G
Sbjct: 872 EEESDSEEEAETLAQVKPS----GKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 927
Query: 749 KVCRAEEGKSPFRESSGDGMKMEGLLNGSS--------DPHQSRL------ASIKAEADK 794
K ++ S ES DG + + DP++S A +A +
Sbjct: 928 K---QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
Query: 795 IYSFTDNAPSPSIGGSSRLENTTP-TQPLTP---LHVVTQNGA------EASSVKTNSPA 844
+ + + S S E+ P TQ LTP +VVT A +AS +S
Sbjct: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
Query: 845 YSDISDAGEDGEG---KVDSV------KSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGF 895
S G+ EG +VDS S + + +G K P P+ + Q
Sbjct: 1045 ESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ-----QAT 1099
Query: 896 ESYYSPSYAQSSPGALNPSSQAGVESQALKTKRD--EEPESIEGKVKNDICEEKKPELSS 953
++ S ++ S + + S + G Q K+ P E V+ E + ++ +
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVA 1159
Query: 954 SSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQS 1013
SQ P + + +Q + P S S + L + + +Q + Q+
Sbjct: 1160 PSQSLLSGYMTPGLTPAN---SQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAG 1216
Query: 1014 LEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGAD 1073
+ + G K+A G +++ ++ P TL ++T + P E
Sbjct: 1217 MLSPKTG-GKEAASGTTPQKSRKPKKGAGNPQAS-TLALQSNITQCLLGQPWPLNEAQVQ 1274
Query: 1074 PAKSVIIPKL---------DDSSKLPGQAPEGLKVKLSD---ASHLSKEASEAKTGAECG 1121
+ ++ +L D + + + E K KLS A+ + + K GA G
Sbjct: 1275 ASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEG 1334
Query: 1122 RQAEMDPILWY----------------------------------RQEAEPRMWTYV--- 1144
+A + P +E + M T
Sbjct: 1335 GEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGD 1394
Query: 1145 --YPAKYSDIKSEDERWK--EERDRKLKEERSRSKDS 1177
P + K D+R K E++++K K +++ +KDS
Sbjct: 1395 QSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1431
Score = 49.3 bits (116), Expect = 3e-05
Identities = 161/809 (19%), Positives = 280/809 (34%), Gaps = 137/809 (16%)
Query: 372 GKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVK 431
GK R ++ N T + + S + A G +SS +SS DV+
Sbjct: 154 GKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVE 213
Query: 432 ASPSSANKRKNKPLSDMELNSSSEDSKGSKRV-RTNSMGSATGPLPGTKVEPTVLDRNCP 490
PS KP + S+++S K +G T + G + P
Sbjct: 214 GKPSV------KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPA------- 260
Query: 491 SPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGD-SEYGEEPILHADLGSCN 549
K+ K KPE + + SE G E A G+ +
Sbjct: 261 -------------KRAK------------------KPEEESESSEEGSESEEEAPAGTRS 289
Query: 550 GASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGS 609
S+K A SA K + +P+P K + + +G+ + D + S + S
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGKGATPAPPGK--AGAVASQTKAGKPEEDSESSSEESS 347
Query: 610 DDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARP--IAPAIPPQQ 667
D +E + A L+ K K +S ++ P K A P PA+ Q
Sbjct: 348 DS-----EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 668 IYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLK----PIQPKP---TVMGEPFTVNPA 720
+ + +++ S A+ +PQ++ P + P P PA
Sbjct: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 721 LTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEE----GKSP-FRESSGDGMKMEGLLN 775
+ K+++ + SS+E +S A + GKSP + +S GM G
Sbjct: 463 AAQVQ-VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 521
Query: 776 GSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEA 835
G P + A+ A+ K + +++ S S S + PT N +A
Sbjct: 522 GPVPPGKVGPATPSAQVGK---WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578
Query: 836 SSVKTNSPAYSDISDAG------------EDGEGKVDSVKSKDAEQ----LVKEGAKKTL 879
T+SPA AG ++ E +S S D+E+ + AK L
Sbjct: 579 K--PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
Query: 880 FPPQPQ-----------SKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKR 928
PQ + +K +P G ++ A +SP +P+ G + A +
Sbjct: 637 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA-TSPAGSSPAVAGGTQRPAEDSSS 695
Query: 929 DEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQ 988
EE +S EE+K L+ + Q + + + + A VP G Q
Sbjct: 696 SEESDS----------EEEKTGLAVTVGQAKSVGKGLQV--------KAASVPVKGSLGQ 737
Query: 989 SYHTHL-------LSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWK 1041
L ++ A +Q+ E + +S ++ + + +K+ +A
Sbjct: 738 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797
Query: 1042 QKPSIPPTLTK----APSLTDLVKSGPGKAKEPGADPAKSVI-------IPKLDDSSKLP 1090
+ PS T++ + + P K K P +P S + +P + +
Sbjct: 798 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857
Query: 1091 GQAPEGLKVKLSDASHLSKEASEAKTGAE 1119
QA G + + S EA+T A+
Sbjct: 858 AQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Score = 48.5 bits (114), Expect = 4e-05
Identities = 179/987 (18%), Positives = 345/987 (34%), Gaps = 191/987 (19%)
Query: 15 ANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKF 74
++P+ T +S +E + + +A+ K +L + S +G P++ + + K
Sbjct: 79 SDPISTSESSEEEE--------EAEAETAKATPRLASTNSSVLGADLPSS---MKEKAKA 127
Query: 75 VTPVPGPQGKE------GKSKSK--RSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSG 126
T G G GK+ + KS + +++P+ T+L + +E S +
Sbjct: 128 ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 127 DGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVL 186
G + G +A +S + S E + S K + S K+
Sbjct: 188 PGMVSAG-----------QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 187 QPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVK 246
+ P G+ G G AL P +PEE E ++
Sbjct: 237 KAAPAPGKVGDVTPQV----------------KGGALPPAKRAKKPEE---ESESSEEGS 277
Query: 247 SEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPC 306
+ E+P T + + + V S+P + + + A+A++ + P
Sbjct: 278 ESEEEAPAGTRSQVKASEKILQVRA-ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPE 336
Query: 307 EPGTSVNLEGI-VWQETEDGMLVVNVTWRNKT-YVGTLLDCTRHDW------APP----- 353
E S + E +ET ++ KT VG + APP
Sbjct: 337 EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP 396
Query: 354 ---------RFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATA----SDSKGTSNSSK 400
R DS +S E + + +P+ P A+A S KG + +
Sbjct: 397 AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 401 TRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGS 460
+ G + + + + R + + D +A ++ N + KPL S K +
Sbjct: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREAL-AAMNAAQVKPLG------KSPQVKPA 509
Query: 461 KRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAH 520
+ +G GP+P KV P PS + K+ +
Sbjct: 510 STMGMGPLGKGAGPVPPGKVGPAT-----PSAQVG-----------------KWEEDSES 547
Query: 521 TDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPS 580
+ ++S +DG+ P LG+ A + + P + A P V+ P +
Sbjct: 548 SSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 607
Query: 581 SKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLE----RKCMEKEK 636
S+ S + S+D +D + T+ A +L+ + C +K
Sbjct: 608 SESSEE------------------SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
Query: 637 CKKPSSLKPEKI----PSKSLKSARPI--APAIP--PQQIYTFQTATFTAASPGSSSGLT 688
+ + P ++ P K+ + P +PA+ Q+ +++ + S +GL
Sbjct: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 709
Query: 689 ATVAQAMPNSPQLKPIQPKPTVMGE---------PFTVNPALTPAKDKKKKD-KKKKESS 738
TV QA L+ V G P P +T K +K++D + +E S
Sbjct: 710 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 739 KELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSF 798
E+ +P +V K+ +++ ++P +R S K
Sbjct: 770 DSEEAAASPAQV------KTSVKKT-----------QAKANPAAARAPSAKG-------- 804
Query: 799 TDNAPSPSIGGSSRLENTTPTQPLTPLH------VVTQNGAEASSV--KTNSPAYSDISD 850
T +AP + +++ + +P++ P+ V+ + A SV + A +
Sbjct: 805 TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP 864
Query: 851 AGEDGEGKVDSVKSKDAEQLVK---EGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSS 907
+ G + +S ++AE L + G + +K+SP A +
Sbjct: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP---------RKGAAPTP 915
Query: 908 PGALNPS-SQAGVESQALKTKRDEEPE 933
PG PS +QAG + + + + + +
Sbjct: 916 PGKTGPSAAQAGKQDDSGSSSEESDSD 942
Score = 34.3 bits (77), Expect = 0.87
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 11/105 (10%)
Query: 79 PGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAI 138
P K K+KR K+ D + SL S+GA + E + + G G G
Sbjct: 1341 PEKTSTTSKGKAKRDKASGDVKEKKGKGSL--GSQGAKDEPEEELQKGMGTVEG------ 1392
Query: 139 APKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDP 183
G + K+ + S K K++ K KK++++ T + P
Sbjct: 1393 ---GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1434
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 57.0 bits (136), Expect = 1e-07
Identities = 250/1298 (19%), Positives = 434/1298 (33%), Gaps = 196/1298 (15%)
Query: 14 DANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEV----GIPAPNAVATLP 69
D++ +T S DE D+ + ++ Q K +KE PAP V +
Sbjct: 197 DSSSEDTSSSSDETDV-------EGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVT 249
Query: 70 DNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGA 129
+K P + K+ + +S+ S+ G ++ + P T S+ AS+K +Q R+
Sbjct: 250 PQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAG---TRSQVKASEKILQVRAASAP 306
Query: 130 NAG--GLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQ 187
G G A AP G + A AS++ AG +E SSS+ + E L
Sbjct: 307 AKGTPGKGATPAPPG-KAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAK-----ALL 360
Query: 188 PVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVKS 247
G+ Q G+A G+ PG P K + + E + + +
Sbjct: 361 QAKASGKTSQV-GAASAPAKESPRKGAAPAPPGKT-GPAVAKAQAGKREEDSQSSSEESD 418
Query: 248 EKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCE 307
+ E+P S Q+ + + A P GP
Sbjct: 419 SEEEAPAQAKP---------------SGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAA 463
Query: 308 PGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDC-TRHDWAPPRFCDSPTSDLEMR 366
V ++ ED + ++ + + + P+ P S + M
Sbjct: 464 AQVQVG------KQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQV--KPASTMGMG 515
Query: 367 N-GRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGR----------RGSQN 415
G+G G + P P +A + S SS + +S G + N
Sbjct: 516 PLGKGAGP-VPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGN 574
Query: 416 SSEHRPPAS-STSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGP 474
+ +P +S + KA P + + KP+ + E + S DS S+ + P
Sbjct: 575 ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKP 634
Query: 475 ---LPGTKVEPTVLDRNCPS---PVLIDCPHPNCNKKYKHINGLKYHQAHA--HTDDDSK 526
+P TK P + + PV + P G A +DS
Sbjct: 635 ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
Query: 527 PEADGDSEYGEEPILHADLGSCNG---------ASVSQKGSLSPARSAT------PKVRL 571
+ DSE E+ L +G ASV KGSL + P V
Sbjct: 695 SSEESDSEE-EKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQ 753
Query: 572 VEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLER-- 629
V+ S + ++ + + + ++ + +
Sbjct: 754 VKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVV 813
Query: 630 KCMEKEKCKKPSSLKPE-KIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLT 688
+ K + PS +KP + P S AR PA P TA P SG +
Sbjct: 814 TAAAQAKQRSPSKVKPPVRNPQNSTVLAR--GPASVPSVGKAVATAAQAQTGPEEDSGSS 871
Query: 689 ATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPG 748
+ + + L ++P G+ + AL PAK+ +K K S G
Sbjct: 872 EEESDSEEEAETLAQVKPS----GKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 927
Query: 749 KVCRAEEGKSPFRESSGDGMKMEGLLNGSS--------DPHQSRL------ASIKAEADK 794
K ++ S ES DG + + DP++S A +A +
Sbjct: 928 K---QDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTP 984
Query: 795 IYSFTDNAPSPSIGGSSRLENTTP-TQPLTP---LHVVTQNGA------EASSVKTNSPA 844
+ + + S S E+ P TQ LTP +VVT A +AS +S
Sbjct: 985 RKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSK 1044
Query: 845 YSDISDAGEDGEG---KVDSV------KSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGF 895
S G+ EG +VDS S + + +G K P P+ + Q
Sbjct: 1045 ESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQ-----QAT 1099
Query: 896 ESYYSPSYAQSSPGALNPSSQAGVESQALKTKRD---EEPESIEGKVKNDICEEKKPELS 952
++ S ++ S + + S + G Q K+ P E V+ E + ++
Sbjct: 1100 KAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVV 1159
Query: 953 SSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQ 1012
+ SQ P + + +Q + P S S + L + + +Q + Q+
Sbjct: 1160 APSQSLLSGYMTPGLTPAN---SQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAA 1216
Query: 1013 SLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGA 1072
+ + G K+A G +++ ++ P TL ++T + P E
Sbjct: 1217 GMLSPKTG-GKEAASGTTPQKSRKPKKGAGNPQAS-TLALQSNITQCLLGQPWPLNEAQV 1274
Query: 1073 DPAKSVIIPKL---------DDSSKLPGQAPEGLKVKLSD---ASHLSKEASEAKTGAEC 1120
+ ++ +L D + + + E K KLS A+ + + K GA
Sbjct: 1275 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1334
Query: 1121 GRQAEMDPILWY----------------------------------RQEAEPRMWTYV-- 1144
G +A + P +E + M T
Sbjct: 1335 GGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1394
Query: 1145 ---YPAKYSDIKSEDERWK--EERDRKLKEERSRSKDS 1177
P + K D+R K E++++K K +++ +KDS
Sbjct: 1395 DQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1432
Score = 49.3 bits (116), Expect = 3e-05
Identities = 161/809 (19%), Positives = 280/809 (34%), Gaps = 137/809 (16%)
Query: 372 GKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVK 431
GK R ++ N T + + S + A G +SS +SS DV+
Sbjct: 154 GKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVE 213
Query: 432 ASPSSANKRKNKPLSDMELNSSSEDSKGSKRV-RTNSMGSATGPLPGTKVEPTVLDRNCP 490
PS KP + S+++S K +G T + G + P
Sbjct: 214 GKPSV------KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPA------- 260
Query: 491 SPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGD-SEYGEEPILHADLGSCN 549
K+ K KPE + + SE G E A G+ +
Sbjct: 261 -------------KRAK------------------KPEEESESSEEGSESEEEAPAGTRS 289
Query: 550 GASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGS 609
S+K A SA K + +P+P K + + +G+ + D + S + S
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGKGATPAPPGK--AGAVASQTKAGKPEEDSESSSEESS 347
Query: 610 DDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARP--IAPAIPPQQ 667
D +E + A L+ K K +S ++ P K A P PA+ Q
Sbjct: 348 DS-----EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 668 IYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLK----PIQPKP---TVMGEPFTVNPA 720
+ + +++ S A+ +PQ++ P + P P PA
Sbjct: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 721 LTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEE----GKSP-FRESSGDGMKMEGLLN 775
+ K+++ + SS+E +S A + GKSP + +S GM G
Sbjct: 463 AAQVQ-VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 521
Query: 776 GSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEA 835
G P + A+ A+ K + +++ S S S + PT N +A
Sbjct: 522 GPVPPGKVGPATPSAQVGK---WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578
Query: 836 SSVKTNSPAYSDISDAG------------EDGEGKVDSVKSKDAEQ----LVKEGAKKTL 879
T+SPA AG ++ E +S S D+E+ + AK L
Sbjct: 579 K--PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
Query: 880 FPPQPQ-----------SKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKR 928
PQ + +K +P G ++ A +SP +P+ G + A +
Sbjct: 637 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA-TSPAGSSPAVAGGTQRPAEDSSS 695
Query: 929 DEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQ 988
EE +S EE+K L+ + Q + + + + A VP G Q
Sbjct: 696 SEESDS----------EEEKTGLAVTVGQAKSVGKGLQV--------KAASVPVKGSLGQ 737
Query: 989 SYHTHL-------LSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWK 1041
L ++ A +Q+ E + +S ++ + + +K+ +A
Sbjct: 738 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797
Query: 1042 QKPSIPPTLTK----APSLTDLVKSGPGKAKEPGADPAKSVI-------IPKLDDSSKLP 1090
+ PS T++ + + P K K P +P S + +P + +
Sbjct: 798 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857
Query: 1091 GQAPEGLKVKLSDASHLSKEASEAKTGAE 1119
QA G + + S EA+T A+
Sbjct: 858 AQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Score = 48.5 bits (114), Expect = 4e-05
Identities = 179/987 (18%), Positives = 345/987 (34%), Gaps = 191/987 (19%)
Query: 15 ANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKF 74
++P+ T +S +E + + +A+ K +L + S +G P++ + + K
Sbjct: 79 SDPISTSESSEEEE--------EAEAETAKATPRLASTNSSVLGADLPSS---MKEKAKA 127
Query: 75 VTPVPGPQGKE------GKSKSK--RSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSG 126
T G G GK+ + KS + +++P+ T+L + +E S +
Sbjct: 128 ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 127 DGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVL 186
G + G +A +S + S E + S K + S K+
Sbjct: 188 PGMVSAG-----------QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 187 QPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVK 246
+ P G+ G G AL P +PEE E ++
Sbjct: 237 KAAPAPGKVGDVTPQV----------------KGGALPPAKRAKKPEE---ESESSEEGS 277
Query: 247 SEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPC 306
+ E+P T + + + V S+P + + + A+A++ + P
Sbjct: 278 ESEEEAPAGTRSQVKASEKILQVRA-ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPE 336
Query: 307 EPGTSVNLEGI-VWQETEDGMLVVNVTWRNKT-YVGTLLDCTRHDW------APP----- 353
E S + E +ET ++ KT VG + APP
Sbjct: 337 EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP 396
Query: 354 ---------RFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATA----SDSKGTSNSSK 400
R DS +S E + + +P+ P A+A S KG + +
Sbjct: 397 AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 401 TRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGS 460
+ G + + + + R + + D +A ++ N + KPL S K +
Sbjct: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREAL-AAMNAAQVKPLG------KSPQVKPA 509
Query: 461 KRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAH 520
+ +G GP+P KV P PS + K+ +
Sbjct: 510 STMGMGPLGKGAGPVPPGKVGPAT-----PSAQVG-----------------KWEEDSES 547
Query: 521 TDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPS 580
+ ++S +DG+ P LG+ A + + P + A P V+ P +
Sbjct: 548 SSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 607
Query: 581 SKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLE----RKCMEKEK 636
S+ S + S+D +D + T+ A +L+ + C +K
Sbjct: 608 SESSEE------------------SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
Query: 637 CKKPSSLKPEKI----PSKSLKSARPI--APAIP--PQQIYTFQTATFTAASPGSSSGLT 688
+ + P ++ P K+ + P +PA+ Q+ +++ + S +GL
Sbjct: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 709
Query: 689 ATVAQAMPNSPQLKPIQPKPTVMGE---------PFTVNPALTPAKDKKKKD-KKKKESS 738
TV QA L+ V G P P +T K +K++D + +E S
Sbjct: 710 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 739 KELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSF 798
E+ +P +V K+ +++ ++P +R S K
Sbjct: 770 DSEEAAASPAQV------KTSVKKT-----------QAKANPAAARAPSAKG-------- 804
Query: 799 TDNAPSPSIGGSSRLENTTPTQPLTPLH------VVTQNGAEASSV--KTNSPAYSDISD 850
T +AP + +++ + +P++ P+ V+ + A SV + A +
Sbjct: 805 TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP 864
Query: 851 AGEDGEGKVDSVKSKDAEQLVK---EGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSS 907
+ G + +S ++AE L + G + +K+SP A +
Sbjct: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP---------RKGAAPTP 915
Query: 908 PGALNPS-SQAGVESQALKTKRDEEPE 933
PG PS +QAG + + + + + +
Sbjct: 916 PGKTGPSAAQAGKQDDSGSSSEESDSD 942
Score = 34.3 bits (77), Expect = 0.87
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 11/105 (10%)
Query: 79 PGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAI 138
P K K+KR K+ D + SL S+GA + E + + G G G
Sbjct: 1342 PEKTSTTSKGKAKRDKASGDVKEKKGKGSL--GSQGAKDEPEEELQKGMGTVEG------ 1393
Query: 139 APKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDP 183
G + K+ + S K K++ K KK++++ T + P
Sbjct: 1394 ---GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1435
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 55.5 bits (132), Expect = 4e-07
Identities = 177/849 (20%), Positives = 302/849 (35%), Gaps = 113/849 (13%)
Query: 378 NSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSA 437
+S+T +NE T + T KT+AG + KG+R ++S+ S + D K S+
Sbjct: 711 SSDTDINEIHT---NHKTLYDLKTQAGKDDKGKRKRKSST------SGSDFDTKKGKSAK 761
Query: 438 NKRKNKPLSDMELNSSSEDSKGSKRVRTNS-MGSATGP---LPGTKVEPTVLDRNCPSPV 493
+ +K + SS+ DS+ K +++ S +G+A +P TK + D
Sbjct: 762 SSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKG 821
Query: 494 LIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASV 553
+ + H N + + + T ++ D D+ E L L AS
Sbjct: 822 MDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIME---LRDRLPKKQQASA 878
Query: 554 SQKG--SLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDD 611
S G LS + + + + SK CKK G D L D S
Sbjct: 879 STDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS-- 936
Query: 612 GPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTF 671
DETS D D + K +EK KKPS K + I +Q Y
Sbjct: 937 -----DETSED--DKKQSKKGTEEK-KKPSDFKKK---------------VIKMEQQY-- 971
Query: 672 QTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKD 731
SS G + +P ++ PK + T + K + K
Sbjct: 972 ---------ESSSDG-----TEKLPEREEICHF-PKGIKQIKNGTTDGEKKSKKIRDKTS 1016
Query: 732 KKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAE 791
KKK E S E G C + E K + G K LL SS Q +S +
Sbjct: 1017 KKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS---D 1073
Query: 792 ADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDA 851
+K YS ++ + S R+E + L+ + + +SS SD ++
Sbjct: 1074 TEK-YSMKEDGCNSSDKRLKRIE-LRERRNLSSKRNTKEIQSGSSS--------SDAEES 1123
Query: 852 GEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGAL 911
ED + K SK +VKE + +L + + SS +
Sbjct: 1124 SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQ-------------ADITSSSSSDI 1170
Query: 912 NPSSQAGV-ESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQ 970
Q + E + + K E++ C+ E S S +V + +
Sbjct: 1171 EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPE 1230
Query: 971 SLYYNQYAYVPPYGYSDQSYHTHLLS-TNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGL 1029
+ + + +L S + + + EE +KR + ++ D++A+ +
Sbjct: 1231 NRIAKKMLL--------EEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1282
Query: 1030 KEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKL 1089
+ EE K KP L + +SG K +P K K + K+
Sbjct: 1283 NSESDSDSEESK-KPRYRHRLLRHKLTVSDGESGEEKKTKP-----KEHKEVKGRNRRKV 1336
Query: 1090 PGQAPEGLKVKLSDAS-HLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAK 1148
+ E + S S +S+ E + ++AE++ ++ + R V
Sbjct: 1337 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDS 1396
Query: 1149 YSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTS----------SDCKLPTSEE 1198
S+ KS E +EE++ + +EE ++ + D +S D KL T +
Sbjct: 1397 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQ 1456
Query: 1199 SRLGSKEPR 1207
+ L +E R
Sbjct: 1457 NALKEEEER 1465
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 55.5 bits (132), Expect = 4e-07
Identities = 177/849 (20%), Positives = 302/849 (35%), Gaps = 113/849 (13%)
Query: 378 NSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSA 437
+S+T +NE T + T KT+AG + KG+R ++S+ S + D K S+
Sbjct: 749 SSDTDINEIHT---NHKTLYDLKTQAGKDDKGKRKRKSST------SGSDFDTKKGKSAK 799
Query: 438 NKRKNKPLSDMELNSSSEDSKGSKRVRTNS-MGSATGP---LPGTKVEPTVLDRNCPSPV 493
+ +K + SS+ DS+ K +++ S +G+A +P TK + D
Sbjct: 800 SSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKG 859
Query: 494 LIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASV 553
+ + H N + + + T ++ D D+ E L L AS
Sbjct: 860 MDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIME---LRDRLPKKQQASA 916
Query: 554 SQKG--SLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDD 611
S G LS + + + + SK CKK G D L D S
Sbjct: 917 STDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQS-- 974
Query: 612 GPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTF 671
DETS D D + K +EK KKPS K + I +Q Y
Sbjct: 975 -----DETSED--DKKQSKKGTEEK-KKPSDFKKK---------------VIKMEQQY-- 1009
Query: 672 QTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKD 731
SS G + +P ++ PK + T + K + K
Sbjct: 1010 ---------ESSSDG-----TEKLPEREEICHF-PKGIKQIKNGTTDGEKKSKKIRDKTS 1054
Query: 732 KKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAE 791
KKK E S E G C + E K + G K LL SS Q +S +
Sbjct: 1055 KKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSS---D 1111
Query: 792 ADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDA 851
+K YS ++ + S R+E + L+ + + +SS SD ++
Sbjct: 1112 TEK-YSMKEDGCNSSDKRLKRIE-LRERRNLSSKRNTKEIQSGSSS--------SDAEES 1161
Query: 852 GEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGAL 911
ED + K SK +VKE + +L + + SS +
Sbjct: 1162 SEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQ-------------ADITSSSSSDI 1208
Query: 912 NPSSQAGV-ESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQ 970
Q + E + + K E++ C+ E S S +V + +
Sbjct: 1209 EDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDDDDNDPE 1268
Query: 971 SLYYNQYAYVPPYGYSDQSYHTHLLS-TNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGL 1029
+ + + +L S + + + EE +KR + ++ D++A+ +
Sbjct: 1269 NRIAKKMLL--------EEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1320
Query: 1030 KEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKL 1089
+ EE K KP L + +SG K +P K K + K+
Sbjct: 1321 NSESDSDSEESK-KPRYRHRLLRHKLTVSDGESGEEKKTKP-----KEHKEVKGRNRRKV 1374
Query: 1090 PGQAPEGLKVKLSDAS-HLSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAK 1148
+ E + S S +S+ E + ++AE++ ++ + R V
Sbjct: 1375 SSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDS 1434
Query: 1149 YSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTS----------SDCKLPTSEE 1198
S+ KS E +EE++ + +EE ++ + D +S D KL T +
Sbjct: 1435 SSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQ 1494
Query: 1199 SRLGSKEPR 1207
+ L +E R
Sbjct: 1495 NALKEEEER 1503
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 54.7 bits (130), Expect = 6e-07
Identities = 100/470 (21%), Positives = 163/470 (34%), Gaps = 55/470 (11%)
Query: 38 LDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGK 97
LD + + D +E IP + + LP + K P P +K + K+ K
Sbjct: 2251 LDLEDDGDLITVEFDDGDTGRIPLSH-IRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSK 2309
Query: 98 DTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSK 157
DT + G + + GA K +GR A A G AA +G+ S +A +
Sbjct: 2310 DTGEGKDGGTAGSEEPGA--KARGRGRK-PSAKAKGDRAATLEEGNPTDEVPSTPLA-LE 2365
Query: 158 KEKENSSSKSKKERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAI 217
S KS E + + P QP P + + A P + ++
Sbjct: 2366 PSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPA---FTSCPAPEPFAELPAPATSL 2422
Query: 218 EPGAALNPLGTKPEPEEGE--------------NECRLLKKVKSEKMESPVSTPAVLPIH 263
P + T+P+P++ E LL K+ E + SP S A +
Sbjct: 2423 APAPLITMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALL 2482
Query: 264 LLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETE 323
L P + +L + P G EP W +
Sbjct: 2483 LREDPGAGGWQEPKSLL--------------SLGSYPPAAGSSEPKAP-------WPKAT 2521
Query: 324 DGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLE-MRNGRGRGKRMRPNSNTP 382
DG L G L T D P+ D ++ + +S++
Sbjct: 2522 DGDLAQEP--------GPGL--TFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSS 2571
Query: 383 VNETATASDSKGTSNSSKTR-AGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRK 441
+ +++ S+++G K G + GR S SS PASS+S +S SS++
Sbjct: 2572 SSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSS 2631
Query: 442 NKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPS 491
+ S +SSS S S ++S S++ + T D +C S
Sbjct: 2632 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSS 2681
Score = 35.4 bits (80), Expect = 0.39
Identities = 114/571 (19%), Positives = 177/571 (30%), Gaps = 105/571 (18%)
Query: 156 SKKEKENSSSKSKKERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGS- 214
S K + +SK E +G GT ++PG GRG + A D A G+
Sbjct: 2299 SAKRRSRKTSKDTGEGKDG-GTAGSEEPGA----KARGRGRKPSAKAKGDRAATLEEGNP 2353
Query: 215 --------IAIEPGAALNPLGTKPEPEEGENECRLLKKVKSEKMESP---VSTPAVLPIH 263
+A+EP + + PEP + + + + +P S PA P
Sbjct: 2354 TDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFA 2413
Query: 264 LLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETE 323
L + +P ++ + A E GP PG E
Sbjct: 2414 ELPAPATSLAPAP----LITMPATRPKPKKARAAEESGAKGPRRPG-------------E 2456
Query: 324 DGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPV 383
+ L+V + H+ L +R G G P S +
Sbjct: 2457 EAELLVKLD---------------HEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSL 2501
Query: 384 NETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNK 443
A+ SS+ +A + + P T ED +P S +K + +
Sbjct: 2502 GSYPPAA------GSSEPKA----PWPKATDGDLAQEPGPGLTFED-SGNPKSPDKAQAE 2550
Query: 444 PLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCN 503
E SSS S GS ++S S + G + D C
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGS-ETEGEEEGDKNGDGGC-------------- 2595
Query: 504 KKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPAR 563
G A + + P + S + S + +S S S S +
Sbjct: 2596 -------GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 564 SATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDA 623
S++ S S SS S+ S D D S+ SDD + A
Sbjct: 2649 SSS---------SSSSSSSSSSSSSSSSSSSSTTDED----SSCSSDDEAAPAPTAGPSA 2695
Query: 624 FDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGS 683
+L K ++ +PS+ P K K+ P A PPQ Q A G+
Sbjct: 2696 QAALPTKATKQAGKARPSAHSPGK------KTPAPQPQAPPPQPTQPLQ----PKAQAGA 2745
Query: 684 SSGLTATVAQAMPNSPQLKPIQPKPTVMGEP 714
S +P + +L Q P+V P
Sbjct: 2746 KSRPKKREGVHLPTTKELAKRQRLPSVENRP 2776
Score = 35.0 bits (79), Expect = 0.51
Identities = 29/131 (22%), Positives = 51/131 (38%), Gaps = 12/131 (9%)
Query: 110 TPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKK 169
+P+ ++S S +++ ++ + S ++ +S S + S +SSS S
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2670
Query: 170 ERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSI---AIEPG---AAL 223
++ +CS D P P G Q A + T A + G A PG A
Sbjct: 2671 STTDEDSSCSSDDEAA--PAPTAGPSAQ----AALPTKATKQAGKARPSAHSPGKKTPAP 2724
Query: 224 NPLGTKPEPEE 234
P P+P +
Sbjct: 2725 QPQAPPPQPTQ 2735
Score = 34.7 bits (78), Expect = 0.67
Identities = 82/366 (22%), Positives = 113/366 (30%), Gaps = 63/366 (17%)
Query: 1019 RGVDKKAEMGLKEREAALKEEWKQKPSIPPT-LTKAPSLTDLVKSGPG-----KAKEPGA 1072
RG +K K AA EE +P T L PS T K P +AK P A
Sbjct: 2330 RGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKA 2389
Query: 1073 DPAKS---------VIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQ 1123
PA P + ++LP A L + +A+ E G +
Sbjct: 2390 RPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAK 2449
Query: 1124 AEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDG 1183
P +EAE +K + E + +K KE +D P G
Sbjct: 2450 GPRRP----GEEAELL------------VKLDHEGVTSPKSKKAKEALLLRED--PGAGG 2491
Query: 1184 KESTSSDCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYSQSYDPNHPS 1243
+ S L S GS EP+ L Q G ++ S +P P
Sbjct: 2492 WQEPKSLLSLG-SYPPAAGSSEPKAPWPKATDGDLAQEPG-----PGLTFEDSGNPKSPD 2545
Query: 1244 YRSMPAVMMQNYPGSYLPSS------YSFSPYGSKVSGGEDADK---------------- 1281
+ S SS S S GS+ G E+ DK
Sbjct: 2546 KAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAA 2605
Query: 1282 --ARASPSVTCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVVGGGGSCS 1339
ASP+ + SSS S + +S S S + S +S S S
Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
Query: 1340 SVGGAS 1345
S +S
Sbjct: 2666 SSSSSS 2671
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 52.8 bits (125), Expect = 2e-06
Identities = 134/666 (20%), Positives = 220/666 (33%), Gaps = 135/666 (20%)
Query: 339 VGTLLDCTRHDWAPPRF-----CDS-------PTSDLEMRN-GRGRGKRMRPNSNTPVNE 385
V +L H W PP C + PT + + N G G KR P+ +
Sbjct: 316 VDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPS------K 369
Query: 386 TATASDSKGT-SNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKP 444
T+ SK + K + +S G + + P S++ S + N R
Sbjct: 370 TSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSR---- 425
Query: 445 LSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNK 504
D +S SE S GS +S + P P P P
Sbjct: 426 -DDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPE--------------PEPPPTN 470
Query: 505 KYKHINGLKYHQAH----AHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLS 560
K++ N L H A + D + P + G + G E G S +
Sbjct: 471 KWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGRE----------QGTGNSYTDTSG 520
Query: 561 PARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETS 620
P +++ +P SK KG + S G P+ D T+
Sbjct: 521 PKETSSA--------TPGRDSKTIQKG---------------SESGRGRQKSPAQSDSTT 557
Query: 621 NDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAAS 680
+R+ + K++ KK E+ P LK +T A+S
Sbjct: 558 -------QRRTVGKKQPKKAEKAAAEE-PRGGLKIES--------------ETPVDLASS 595
Query: 681 PGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAK------DKKKKDKKK 734
SS AT PN + P+PT + + + D D +
Sbjct: 596 MPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDE 655
Query: 735 KES-------SKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLAS 787
ES K ES TP K EE S FR+ M+ + LL+ S+P
Sbjct: 656 SESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLI 715
Query: 788 IKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSD 847
+K + + + +R+ P + P +N E + + A
Sbjct: 716 VKIDLNLL---------------TRIPG-KPYKETEPPKGEKKNVPEKHTREAQKQASEK 759
Query: 848 ISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSS 907
+S+ G+ D ++ ++++ E P + S E PS A
Sbjct: 760 VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPV 819
Query: 908 PGALNPSSQAG------VESQALKTKRDEEPE-SIEGKVKNDICEEKKPELSSSSQQPSV 960
P + +P ++ G +S +LK+ + E S K + ++KK E +SS V
Sbjct: 820 P-SKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV 878
Query: 961 IQQRPN 966
++ P+
Sbjct: 879 KEKAPS 884
Score = 42.4 bits (98), Expect = 0.003
Identities = 161/846 (19%), Positives = 289/846 (34%), Gaps = 88/846 (10%)
Query: 76 TPV-PGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGL 134
TPV P P + + +S +SG + + + G+S T S G +E SG + G
Sbjct: 109 TPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKG- 167
Query: 135 VAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKK-----ERSEGVGTCSEKDPGVL--Q 187
GSE + S S + +SS S+ E + S +DP
Sbjct: 168 -----QHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDS 222
Query: 188 PVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKP--EPEEGENECRLLKKV 245
P + GQ+ + + S+ +P A + P+ + EP+
Sbjct: 223 PSRVPFSSGQH-STQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHG 281
Query: 246 KSEKMESPVS----TPAVLPIHLLVPVVNNDISSPCEQIMVRTRS--VGVNTCDVALATE 299
S P S T +P L + D+S E + T S + TE
Sbjct: 282 NSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTE 341
Query: 300 PECLG-PCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDCTRHDWAPPRFCD- 357
P P + N G Q+ + N L + D + CD
Sbjct: 342 PSKFPFPTKESQQSNF-GTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDK 400
Query: 358 -----SPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRG 412
+P S+ E + G NS + + + S G+ + S++ + ++S+
Sbjct: 401 TMPRSTPGSNSEPSHHNSEG---ADNSRDDSSSHSGSESSSGSDSESES-SSSDSEANEP 456
Query: 413 SQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELN---SSSEDSKGSKRVRTNSMG 469
SQ++S P + + + N K P S ++ N S +G ++ NS
Sbjct: 457 SQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYT 516
Query: 470 SATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEA 529
+GP + P + + +G ++ A +D ++
Sbjct: 517 DTSGPKETSSATP---------------GRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
Query: 530 DGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSS--KFSTKG 587
G + + A+ +G L S TP V+ S PSS K +TKG
Sbjct: 562 VGKKQPKKAE---------KAAAEEPRGGLK-IESETP----VDLASSMPSSRHKAATKG 607
Query: 588 LCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEK 647
K + E + + S + S + ++ E P S + K
Sbjct: 608 SRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPK 667
Query: 648 IPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPK 707
P + P+ P+ ++ F+ F SP L + +++ P + I
Sbjct: 668 YPE---SNRTPVKPSSVEEEDSFFRQRMF---SPMEEKELLSPLSEPDDRYPLIVKIDLN 721
Query: 708 --PTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSG 765
+ G+P+ P +KK +K +++ S K R + + R S
Sbjct: 722 LLTRIPGKPY--KETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASES 779
Query: 766 DGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPL 825
K E + P +R +S ++ A + D PSP+ S+ T+ +
Sbjct: 780 KKPKTEDKNSAGHKPSSNRESSKQSAAKE----KDLLPSPAGPVPSK---DPKTEHGSRK 832
Query: 826 HVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGA--KKTLFPPQ 883
++Q+ + SS +N ++ + K K+ + + VKE A + PP
Sbjct: 833 RTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPS 892
Query: 884 PQSKDS 889
+ DS
Sbjct: 893 APTLDS 898
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 52.0 bits (123), Expect = 4e-06
Identities = 241/1265 (19%), Positives = 400/1265 (31%), Gaps = 170/1265 (13%)
Query: 14 DANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKL---EMSGSKEVGIPAPNAVATLPD 70
D++ +T S DE D+ V K +K+ + + G P A P
Sbjct: 197 DSSSEDTSSSSDETDVEV------------KASEKILQVRAASAPAKGTPGKGATPAPPG 244
Query: 71 NIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGAN 130
V GK + S+ D+ + TP ++ + +V S
Sbjct: 245 KAGAVASQT-KAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKE 303
Query: 131 AGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQPVP 190
+ AA AP G A A A + K +E+S S S++ SE K G V
Sbjct: 304 SPRKGAAPAPPGKTGPAVAK---AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVR 360
Query: 191 LGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVKSEKM 250
+ G G A + ++ EE +++ L + + ++
Sbjct: 361 AASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQV 420
Query: 251 ESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGT 310
+ +P V P + + P V V AT +G E +
Sbjct: 421 KPLGKSPQVKPASTMGMGPLGKGAGP------------VPPGKVGPATPSAQVGKWEEDS 468
Query: 311 SVNLEGIVWQETEDGMLVVNVTWRNKTYVGTLLDC---TRHDWAPPRFCDSPTSDLEMRN 367
+ E ++ DG + V + +G +L + PP+ ++
Sbjct: 469 ESSSEES--SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK 526
Query: 368 GRGRGKRMRPNSNTPVNETA----TASDSKGTSNSSKTRAGANSKGRRGSQNSSEHR--- 420
+ +S++ +E A TA+ +K +T+A S + R
Sbjct: 527 PMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGT 586
Query: 421 --PPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGT 478
P + T+ S + +P D +S DS+ K ++G A G
Sbjct: 587 QAPRKAGTATSPAGSSPAVAGGTQRPAEDSS-SSEESDSEEEKTGLAVTVGQAKSVGKGL 645
Query: 479 KVEPTVLD-----RNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDS 533
+V+ + +PVL P + +A D +S E
Sbjct: 646 QVKAASVPVKGSLGQGTAPVLPGKTGPTVTQV----------KAEKQEDSESSEEESDSE 695
Query: 534 EYGEEPI--------LHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSP------ 579
E P A + S KG++S + SPS
Sbjct: 696 EAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVR 755
Query: 580 ---SSKFSTKGLCKKKLSGEG-DTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKE 635
+S +G G+ T A + D G S + S + ++L + +
Sbjct: 756 NPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGK 815
Query: 636 KCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSG-LTATVAQA 694
+ ++L P K + + P P Q + +++ S G A V A
Sbjct: 816 THQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSA 875
Query: 695 MPNSPQLKPIQPKPTVMGE---PFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVC 751
P L + P + G P A TP K + + + SS+ + + P C
Sbjct: 876 QVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQC 935
Query: 752 ----------------------RAEEGKSPFRESS--GDGMKMEGLLNGSSDPHQSRLAS 787
+ G S +ESS DG K EG S + + L
Sbjct: 936 LTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPL 995
Query: 788 IKAEADKIYSFTDNAPSP--SIGGSSRLENTTPTQPLT-PLHVVTQNGAEASSVKTNSPA 844
+A + A P SS +++ T P T P Q K P
Sbjct: 996 TQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPE 1055
Query: 845 YSDISDAGE---DGEGKVDSVKSKDAEQLVKEGAKK--TLFPPQPQSKDSPYYQGFESYY 899
+ A E D E DS + + +GAK TL P +++ ES
Sbjct: 1056 VQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSE 1115
Query: 900 SPSYAQSSP---GALNPS-SQAGVESQALKTKRDEEPE---SIEGKVKNDICEEKKPELS 952
A S G + P + A ++ K D P ++ K D +E KP+ +
Sbjct: 1116 DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA 1175
Query: 953 SSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNT------------- 999
+ P + S Q + P G + T L +N
Sbjct: 1176 AGMLSPKTGGKEA----ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNE 1231
Query: 1000 AYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDL 1059
A Q + + LEQ++ KK KE E K+K S + P
Sbjct: 1232 AQVQASVVKVLTELLEQER----KKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKK 1287
Query: 1060 VKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAE 1119
K G G+ E P K+ S+ G+A S + E K
Sbjct: 1288 KKLGAGEGGEASVSPEKT--------STTSKGKAKR---------DKASGDVKEKKGKGS 1330
Query: 1120 CGRQAEMDPILWYRQEAEPRMWTYV-----YPAKYSDIKSEDERWK--EERDRKLKEERS 1172
G Q D +E + M T P + K D+R K E++++K K +++
Sbjct: 1331 LGSQGAKDEP---EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKA 1387
Query: 1173 RSKDS 1177
+KDS
Sbjct: 1388 STKDS 1392
Score = 36.6 bits (83), Expect = 0.18
Identities = 77/393 (19%), Positives = 136/393 (34%), Gaps = 50/393 (12%)
Query: 571 LVEPHSPSPSSKFSTKGLCKKKLSGEGDTD-LGALSNDGSDDGPSVMDETSNDAFDSLER 629
L+ SP S++ S + EG GA + G D +S D S +
Sbjct: 151 LLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQA-DSSSEDTSSSSDE 209
Query: 630 KCMEKEKCKKPSSLKPEKIPSKSL--KSARPIAPAIPPQQIYTFQTATFTAASPGSSSGL 687
+E + +K ++ P+K K A P PP + + T S
Sbjct: 210 TDVEVKASEKILQVRAASAPAKGTPGKGATPA----PPGKAGAVASQTKAGKPEEDSESS 265
Query: 688 TATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTP 747
+ + + +P K + + G+ V A PAK+ +K +P P
Sbjct: 266 SEESSDSEEETPAAKALL-QAKASGKTSQVGAASAPAKESPRKGA----------APAPP 314
Query: 748 GK----VCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAP 803
GK V +A+ GK RE E SD + A K +
Sbjct: 315 GKTGPAVAKAQAGK---REEDSQSSSEE------SDSEEEAPAQAKP----------SGK 355
Query: 804 SPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVK 863
+P + +S +P + P + G A+ V+ D + E+ + +++
Sbjct: 356 APQVRAASAPAKESPRKGAAPAPP-RKTGPAAAQVQVGKQE-EDSRSSSEESDSDREALA 413
Query: 864 SKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQA 923
+ +A Q VK K P P +G + G PS+Q G +
Sbjct: 414 AMNAAQ-VKPLGKSPQVKPASTMGMGPLGKG-----AGPVPPGKVGPATPSAQVGKWEED 467
Query: 924 LKTKRDEEPESIEGKVKNDICEEKKPELSSSSQ 956
++ +E +S +G+V + ++ L + Q
Sbjct: 468 SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQ 500
Score = 34.3 bits (77), Expect = 0.87
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 11/105 (10%)
Query: 79 PGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAI 138
P K K+KR K+ D + SL S+GA + E + + G G G
Sbjct: 1302 PEKTSTTSKGKAKRDKASGDVKEKKGKGSL--GSQGAKDEPEEELQKGMGTVEG------ 1353
Query: 139 APKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDP 183
G + K+ + S K K++ K KK++++ T + P
Sbjct: 1354 ---GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1395
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 52.0 bits (123), Expect = 4e-06
Identities = 113/555 (20%), Positives = 207/555 (37%), Gaps = 69/555 (12%)
Query: 724 AKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGD-------GMKMEGLLNG 776
A K+K +KK+K +K L K E K+ G K++ +
Sbjct: 184 ATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKT 243
Query: 777 SSDPHQS----RLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNG 832
S P + + A K E Y+F + G + + P P
Sbjct: 244 PSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTE------ 297
Query: 833 AEASSVKTNSPAYSDISDAGEDGEGKVDS-VKSKDAEQLVKEGAKKTLFPPQPQSKDSPY 891
+AS SPA + + E KV S K K+ E + K+ K+T + +
Sbjct: 298 -QASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKA- 355
Query: 892 YQGFESYYSPSYAQSSPGALNPSSQAGVESQ-----ALKTKRDEEPESIEGKVKND---- 942
+++ G + ++QA + + KTK+ E E +GK +
Sbjct: 356 ------------SETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKH 403
Query: 943 ICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYR 1002
+ K P+ S ++ + + + P G ++ +T T +
Sbjct: 404 VEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVP-GKKEEK------TTKTVEQ 456
Query: 1003 QQYEEQQKRQSL----EQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTD 1058
+ +E+ + S ++ +G ++K LKE+E K++ K + K P L
Sbjct: 457 EIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQG 516
Query: 1059 LVKSGPGKAKEPGADPA--KSVIIPKLD---DSSKLPGQAPEGLKVKLSDASHLSKEASE 1113
+ P + A PA + V I K D + PE +K A + K A
Sbjct: 517 KKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTIEKTAKP 576
Query: 1114 AKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRK-LKEER- 1171
T R+ E I + + P+ + V + + ++ KE+ D K L+EE+
Sbjct: 577 KPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESKEKADMKHLREEKV 636
Query: 1172 SRSKDS-----VPKEDGKESTSSDCK-LPTSEESRLGSKEPRPSVHVPVSSPLTQHQS-Y 1224
S K+S V K + S D + +P S++++ G+++ P+ SP++ Q Y
Sbjct: 637 STRKESLQLHNVTKAEKPARVSKDVEDVPASKKAKEGTEDVSPTKQ---KSPISFFQCVY 693
Query: 1225 IPYMHGYSYSQSYDP 1239
+ +GY + + P
Sbjct: 694 LDGYNGYGFQFPFTP 708
Score = 31.2 bits (69), Expect = 7.4
Identities = 51/250 (20%), Positives = 92/250 (36%), Gaps = 26/250 (10%)
Query: 531 GDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCK 590
GD + G+ P + L + S+ SPA + + +K K K
Sbjct: 280 GDLKPGQSPAIPPPLPT---EQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIK 336
Query: 591 KKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPS 650
KK E D+ + + + + A + K + +K KKP+ ++ K
Sbjct: 337 KKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPK-GK 395
Query: 651 KSLKSARPIAPAIPPQQIYTFQT-----------------ATFTAASPGSSSGLTA-TVA 692
K K + + PA P++ ++ + + A PG T TV
Sbjct: 396 KQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVE 455
Query: 693 QAMPNSPQLKP---IQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGK 749
Q + K ++ K + G+ V +L + + KKD+K ++ KE++ P P
Sbjct: 456 QEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVK-PKPPQL 514
Query: 750 VCRAEEGKSP 759
+ EE P
Sbjct: 515 QGKKEEKPEP 524
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 51.2 bits (121), Expect = 7e-06
Identities = 177/872 (20%), Positives = 302/872 (34%), Gaps = 126/872 (14%)
Query: 377 PNSNTPVNETATASDSKGTSNS-SKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPS 435
P TP + + + KGT NS SKT+ N + RG HR + +K S
Sbjct: 132 PVDTTPKHPSQSTVCQKGTPNSASKTKDKVNKRNERGETRL--HRAAIRGDARRIKELIS 189
Query: 436 SANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLI 495
K + + ++G V + + G +V LD + P L
Sbjct: 190 EGADVNVKDFAGWTALHEA-CNRGYYDVAKQLLAA------GAEVNTKGLDDDTP---LH 239
Query: 496 DCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQ 555
D + N YK + L + + + GE P+ A+ + + +
Sbjct: 240 DAAN---NGHYKVVKLLLRYGGNPQQSNRK----------GETPLKVANSPTMVNLLLGK 286
Query: 556 KGSLSPARSATPKVRLVEPHSPSPSSKFS--------TKGLCKKKLSGEGDTDLGALSND 607
S S+T + S +PSS KGL K + E + ++
Sbjct: 287 GTYTSSEESSTESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDE 346
Query: 608 GSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQ 667
D D L +K KE K S + K+ KS IAP +
Sbjct: 347 YEFDEDDEQDRVPPVDDKHLLKKDYRKET-KSNSFISIPKMEVKSYTKNNTIAPKKASHR 405
Query: 668 IYTFQTATFTAA-SPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKD 726
I + + A+ + G+ L + +P S +P K K+
Sbjct: 406 ILSDTSDEEDASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQ-------------KEKN 452
Query: 727 KKKKDKKKKESSKELESPLTPGKVC--RAEEGKSPFRESSGDGMKMEGLLNGS----SDP 780
K KK +KK+ +E+ K C +E S E D + G L GS DP
Sbjct: 453 KVKKKRKKETKGREVRFGKRSDKFCSSESESESSESGEDDRDSLGSSGCLKGSPLVLKDP 512
Query: 781 HQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKT 840
S +S+ +A S S GSS + P+ T H T++ +
Sbjct: 513 --SLFSSL------------SASSTSSHGSSAAQKQNPSH--TDQH--TKHWRTDNWKTI 554
Query: 841 NSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYS 900
+SPA+S++S + ++ S + EG+ P + ++ S
Sbjct: 555 SSPAWSEVSSLSDSTRTRLTSESDYSS-----EGSSVESLKPVRKRQEHRKRASLSEKKS 609
Query: 901 PSYAQSSPGALNPSSQAGVESQALKTKRDEEP-------------------ESIEGKVKN 941
P + S+ GA+ + G + KTK + E + K K+
Sbjct: 610 P-FLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKS 668
Query: 942 DICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAY 1001
D + +LS+ ++ + R + + + + D+ + TN
Sbjct: 669 DKAILLENDLSTENKLKVLKHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDI 728
Query: 1002 RQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVK 1061
+ + E++ R + +++R + +K+ +E+ KEE K+K P +K DL +
Sbjct: 729 SRSFREEKDRSNKAEKERSLKEKSPK--EEKLRLYKEERKKKSKDRP--SKLEKKNDLKE 784
Query: 1062 SGPGKAKE----PGADPAKSVIIPKLDDS-----SKLPGQAPEGLKVKLSD------ASH 1106
K KE + K + + D + +K E K LSD S
Sbjct: 785 DKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSD 844
Query: 1107 LSKEASEAKTGAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDIKS--EDERWKEERD 1164
LS + + K G + P+ YR + + D K D R +E+RD
Sbjct: 845 LSDSSFDFK-----GEDSWDSPVTDYRDMKSDSVAKLILETVKEDSKERRRDSRAREKRD 899
Query: 1165 RKLKEERSRSKDSVPK--EDGKESTSSDCKLP 1194
+ R + +D + K E KE T +P
Sbjct: 900 YREPFFRKKDRDYLDKNSEKRKEQTEKHKSVP 931
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 50.4 bits (119), Expect = 1e-05
Identities = 227/1193 (19%), Positives = 378/1193 (31%), Gaps = 154/1193 (12%)
Query: 83 GKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKG 142
GK + S+ D+ + TP ++ + +V S + AA AP G
Sbjct: 333 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 392
Query: 143 SEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSA 202
A A A + K +E+S S S++ SE K G V +
Sbjct: 393 KTGPAVAK---AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRK 449
Query: 203 GVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVKSEKMESPVSTPAVLPI 262
G G A + ++ EE +++ L + + +++ +P V P
Sbjct: 450 GAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPA 509
Query: 263 HLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQET 322
+ + P V V AT +G E + + E ++
Sbjct: 510 STMGMGPLGKGAGP------------VPPGKVGPATPSAQVGKWEEDSESSSEES--SDS 555
Query: 323 EDGMLVVNVTWRNKTYVGTLLDC---TRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNS 379
DG + V + +G +L + PP+ ++ + +S
Sbjct: 556 SDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESS 615
Query: 380 NTPVNETA----TASDSKGTSNSSKTRAGANSKGRRGSQNSSEHR-----PPASSTSEDV 430
++ +E A TA+ +K +T+A S + R P + T+
Sbjct: 616 DSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 675
Query: 431 KASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLD---- 486
S + +P D +S DS+ K ++G A G +V+ +
Sbjct: 676 AGSSPAVAGGTQRPAEDSS-SSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGS 734
Query: 487 -RNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPI----- 540
+PVL P + +A D +S E E P
Sbjct: 735 LGQGTAPVLPGKTGPTVTQV----------KAEKQEDSESSEEESDSEEAAASPAQVKTS 784
Query: 541 ---LHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSP---------SSKFSTKGL 588
A + S KG++S + SPS +S +G
Sbjct: 785 VKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGP 844
Query: 589 CKKKLSGEG-DTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEK 647
G+ T A + D G S + S + ++L + + + ++L P K
Sbjct: 845 ASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAK 904
Query: 648 IPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSG-LTATVAQAMPNSPQLKPIQP 706
+ + P P Q + +++ S G A V A P L + P
Sbjct: 905 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
Query: 707 KPTVMGE---PFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVC------------ 751
+ G P A TP K + + + SS+ + + P C
Sbjct: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 1024
Query: 752 ----------RAEEGKSPFRESS--GDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFT 799
+ G S +ESS DG K EG S + + L +A +
Sbjct: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKA 1084
Query: 800 DNAPSP--SIGGSSRLENTTPTQPLT-PLHVVTQNGAEASSVKTNSPAYSDISDAGE--- 853
A P SS +++ T P T P Q K P + A E
Sbjct: 1085 SEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSD 1144
Query: 854 DGEGKVDSVKSKDAEQLVKEGAKK--TLFPPQPQSKDSPYYQGFESYYSPSYAQSSP--- 908
D E DS + + +GAK TL P +++ ES A S
Sbjct: 1145 DSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLS 1204
Query: 909 GALNPS-SQAGVESQALKTKRDEEPE---SIEGKVKNDICEEKKPELSSSSQQPSVIQQR 964
G + P + A ++ K D P ++ K D +E KP+ ++ P +
Sbjct: 1205 GYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKE 1264
Query: 965 PNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNT-------------AYRQQYEEQQKR 1011
S Q + P G + T L +N A Q +
Sbjct: 1265 A----ASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLT 1320
Query: 1012 QSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPG 1071
+ LEQ++ KK KE E K+K S + P K G G+ E
Sbjct: 1321 ELLEQER----KKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEAS 1376
Query: 1072 ADPAKSVIIPKLDDSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILW 1131
P K+ S+ G+A S + E K G Q D
Sbjct: 1377 VSPEKT--------STTSKGKAKR---------DKASGDVKEKKGKGSLGSQGAKDEP-- 1417
Query: 1132 YRQEAEPRMWTYV-----YPAKYSDIKSEDERWK--EERDRKLKEERSRSKDS 1177
+E + M T P + K D+R K E++++K K +++ +KDS
Sbjct: 1418 -EEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDS 1469
Score = 49.3 bits (116), Expect = 3e-05
Identities = 161/809 (19%), Positives = 280/809 (34%), Gaps = 137/809 (16%)
Query: 372 GKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVK 431
GK R ++ N T + + S + A G +SS +SS DV+
Sbjct: 154 GKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVE 213
Query: 432 ASPSSANKRKNKPLSDMELNSSSEDSKGSKRV-RTNSMGSATGPLPGTKVEPTVLDRNCP 490
PS KP + S+++S K +G T + G + P
Sbjct: 214 GKPSV------KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPA------- 260
Query: 491 SPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGD-SEYGEEPILHADLGSCN 549
K+ K KPE + + SE G E A G+ +
Sbjct: 261 -------------KRAK------------------KPEEESESSEEGSESEEEAPAGTRS 289
Query: 550 GASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGS 609
S+K A SA K + +P+P K + + +G+ + D + S + S
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGKGATPAPPGK--AGAVASQTKAGKPEEDSESSSEESS 347
Query: 610 DDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARP--IAPAIPPQQ 667
D +E + A L+ K K +S ++ P K A P PA+ Q
Sbjct: 348 DS-----EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 668 IYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLK----PIQPKP---TVMGEPFTVNPA 720
+ + +++ S A+ +PQ++ P + P P PA
Sbjct: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 721 LTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEE----GKSP-FRESSGDGMKMEGLLN 775
+ K+++ + SS+E +S A + GKSP + +S GM G
Sbjct: 463 AAQVQ-VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 521
Query: 776 GSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEA 835
G P + A+ A+ K + +++ S S S + PT N +A
Sbjct: 522 GPVPPGKVGPATPSAQVGK---WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578
Query: 836 SSVKTNSPAYSDISDAG------------EDGEGKVDSVKSKDAEQ----LVKEGAKKTL 879
T+SPA AG ++ E +S S D+E+ + AK L
Sbjct: 579 K--PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
Query: 880 FPPQPQ-----------SKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKR 928
PQ + +K +P G ++ A +SP +P+ G + A +
Sbjct: 637 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA-TSPAGSSPAVAGGTQRPAEDSSS 695
Query: 929 DEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQ 988
EE +S EE+K L+ + Q + + + + A VP G Q
Sbjct: 696 SEESDS----------EEEKTGLAVTVGQAKSVGKGLQV--------KAASVPVKGSLGQ 737
Query: 989 SYHTHL-------LSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWK 1041
L ++ A +Q+ E + +S ++ + + +K+ +A
Sbjct: 738 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797
Query: 1042 QKPSIPPTLTK----APSLTDLVKSGPGKAKEPGADPAKSVI-------IPKLDDSSKLP 1090
+ PS T++ + + P K K P +P S + +P + +
Sbjct: 798 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857
Query: 1091 GQAPEGLKVKLSDASHLSKEASEAKTGAE 1119
QA G + + S EA+T A+
Sbjct: 858 AQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Score = 34.3 bits (77), Expect = 0.87
Identities = 26/105 (24%), Positives = 43/105 (40%), Gaps = 11/105 (10%)
Query: 79 PGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAI 138
P K K+KR K+ D + SL S+GA + E + + G G G
Sbjct: 1379 PEKTSTTSKGKAKRDKASGDVKEKKGKGSL--GSQGAKDEPEEELQKGMGTVEG------ 1430
Query: 139 APKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDP 183
G + K+ + S K K++ K KK++++ T + P
Sbjct: 1431 ---GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP 1472
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 49.3 bits (116), Expect = 3e-05
Identities = 99/462 (21%), Positives = 165/462 (35%), Gaps = 51/462 (11%)
Query: 394 GTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSAN-KRKNKPLSDMELNS 452
G + S+ T + N R + E PPA +TS +SP A+ + PL L
Sbjct: 78 GPTRSAGT-SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 453 SSEDS----KGSKRVRTNSMGS-----ATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCN 503
S+E++ K ++ + +++ + +GP PGT P + R+ + + P P +
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPAPS 195
Query: 504 KKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPAR 563
+ T+ K + EP A G + + S S +
Sbjct: 196 AR-----------PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 564 SATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDA 623
SATP L P PS++ + + S L AL P + DA
Sbjct: 245 SATP---LSSPARSGPSARGTPRAPAHP--SQPKPKGLQALR-------PPQVTPPRKDA 292
Query: 624 FDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGS 683
+L PS K +P +A P+ +PP AT +P S
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPD-NAATPLPATLPPSP----PLATPLPLAPPS 347
Query: 684 SSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELES 743
S + Q +P+ P P Q P++ P P+L + S + S
Sbjct: 348 PSAPPS--LQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPS 405
Query: 744 PLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAP 803
PL + SP +++ + M +S SR AS ++ + +
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPA 465
Query: 804 SPSIGGSSRLENTTPTQPLT--PLHVVTQNGAEASSVKTNSP 843
SP + S + + PLT PL + SS+ ++SP
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQAL-------SSLASHSP 500
Score = 31.2 bits (69), Expect = 7.4
Identities = 32/136 (23%), Positives = 50/136 (36%), Gaps = 14/136 (10%)
Query: 103 TPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKEN 162
TP + GA +K + R AGG+ A P+ + +A + S+
Sbjct: 40 TPAALRVLGAAGAVGRKPLAER------AGGIGGATIPESAPRAGPTRSAGTSSRNPASR 93
Query: 163 SSSKSKKER-------SEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTG-AVEPLGS 214
+ + ER S G + + G +P PLG +G + V G A E
Sbjct: 94 PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 153
Query: 215 IAIEPGAALNPLGTKP 230
A+ GA + G P
Sbjct: 154 SALSAGARRDTSGPTP 169
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 49.3 bits (116), Expect = 3e-05
Identities = 161/809 (19%), Positives = 280/809 (34%), Gaps = 137/809 (16%)
Query: 372 GKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVK 431
GK R ++ N T + + S + A G +SS +SS DV+
Sbjct: 154 GKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVE 213
Query: 432 ASPSSANKRKNKPLSDMELNSSSEDSKGSKRV-RTNSMGSATGPLPGTKVEPTVLDRNCP 490
PS KP + S+++S K +G T + G + P
Sbjct: 214 GKPSV------KPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPA------- 260
Query: 491 SPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGD-SEYGEEPILHADLGSCN 549
K+ K KPE + + SE G E A G+ +
Sbjct: 261 -------------KRAK------------------KPEEESESSEEGSESEEEAPAGTRS 289
Query: 550 GASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGS 609
S+K A SA K + +P+P K + + +G+ + D + S + S
Sbjct: 290 QVKASEKILQVRAASAPAKGTPGKGATPAPPGK--AGAVASQTKAGKPEEDSESSSEESS 347
Query: 610 DDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARP--IAPAIPPQQ 667
D +E + A L+ K K +S ++ P K A P PA+ Q
Sbjct: 348 DS-----EEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQ 402
Query: 668 IYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLK----PIQPKP---TVMGEPFTVNPA 720
+ + +++ S A+ +PQ++ P + P P PA
Sbjct: 403 AGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPA 462
Query: 721 LTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEE----GKSP-FRESSGDGMKMEGLLN 775
+ K+++ + SS+E +S A + GKSP + +S GM G
Sbjct: 463 AAQVQ-VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 521
Query: 776 GSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEA 835
G P + A+ A+ K + +++ S S S + PT N +A
Sbjct: 522 GPVPPGKVGPATPSAQVGK---WEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQA 578
Query: 836 SSVKTNSPAYSDISDAG------------EDGEGKVDSVKSKDAEQ----LVKEGAKKTL 879
T+SPA AG ++ E +S S D+E+ + AK L
Sbjct: 579 K--PTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPAL 636
Query: 880 FPPQPQ-----------SKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKR 928
PQ + +K +P G ++ A +SP +P+ G + A +
Sbjct: 637 KIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTA-TSPAGSSPAVAGGTQRPAEDSSS 695
Query: 929 DEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQ 988
EE +S EE+K L+ + Q + + + + A VP G Q
Sbjct: 696 SEESDS----------EEEKTGLAVTVGQAKSVGKGLQV--------KAASVPVKGSLGQ 737
Query: 989 SYHTHL-------LSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWK 1041
L ++ A +Q+ E + +S ++ + + +K+ +A
Sbjct: 738 GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797
Query: 1042 QKPSIPPTLTK----APSLTDLVKSGPGKAKEPGADPAKSVI-------IPKLDDSSKLP 1090
+ PS T++ + + P K K P +P S + +P + +
Sbjct: 798 RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857
Query: 1091 GQAPEGLKVKLSDASHLSKEASEAKTGAE 1119
QA G + + S EA+T A+
Sbjct: 858 AQAQTGPEEDSGSSEEESDSEEEAETLAQ 886
Score = 48.5 bits (114), Expect = 4e-05
Identities = 179/987 (18%), Positives = 345/987 (34%), Gaps = 191/987 (19%)
Query: 15 ANPVETYDSGDEWDIGVGNLIIDLDADLEKDQQKLEMSGSKEVGIPAPNAVATLPDNIKF 74
++P+ T +S +E + + +A+ K +L + S +G P++ + + K
Sbjct: 79 SDPISTSESSEEEE--------EAEAETAKATPRLASTNSSVLGADLPSS---MKEKAKA 127
Query: 75 VTPVPGPQGKE------GKSKSK--RSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSG 126
T G G GK+ + KS + +++P+ T+L + +E S +
Sbjct: 128 ETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAK 187
Query: 127 DGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEGVGTCSEKDPGVL 186
G + G +A +S + S E + S K + S K+
Sbjct: 188 PGMVSAG-----------QADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPAR 236
Query: 187 QPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKPEPEEGENECRLLKKVK 246
+ P G+ G G AL P +PEE E ++
Sbjct: 237 KAAPAPGKVGDVTPQV----------------KGGALPPAKRAKKPEE---ESESSEEGS 277
Query: 247 SEKMESPVSTPAVLPIHLLVPVVNNDISSPCEQIMVRTRSVGVNTCDVALATEPECLGPC 306
+ E+P T + + + V S+P + + + A+A++ + P
Sbjct: 278 ESEEEAPAGTRSQVKASEKILQVRA-ASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPE 336
Query: 307 EPGTSVNLEGI-VWQETEDGMLVVNVTWRNKT-YVGTLLDCTRHDW------APP----- 353
E S + E +ET ++ KT VG + APP
Sbjct: 337 EDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGP 396
Query: 354 ---------RFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATA----SDSKGTSNSSK 400
R DS +S E + + +P+ P A+A S KG + +
Sbjct: 397 AVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPP 456
Query: 401 TRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGS 460
+ G + + + + R + + D +A ++ N + KPL S K +
Sbjct: 457 RKTGPAAAQVQVGKQEEDSRSSSEESDSDREAL-AAMNAAQVKPLG------KSPQVKPA 509
Query: 461 KRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAH 520
+ +G GP+P KV P PS + K+ +
Sbjct: 510 STMGMGPLGKGAGPVPPGKVGPAT-----PSAQVG-----------------KWEEDSES 547
Query: 521 TDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPS 580
+ ++S +DG+ P LG+ A + + P + A P V+ P +
Sbjct: 548 SSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDN 607
Query: 581 SKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLE----RKCMEKEK 636
S+ S + S+D +D + T+ A +L+ + C +K
Sbjct: 608 SESSEE------------------SSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN 649
Query: 637 CKKPSSLKPEKI----PSKSLKSARPI--APAIP--PQQIYTFQTATFTAASPGSSSGLT 688
+ + P ++ P K+ + P +PA+ Q+ +++ + S +GL
Sbjct: 650 TTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLA 709
Query: 689 ATVAQAMPNSPQLKPIQPKPTVMGE---------PFTVNPALTPAKDKKKKD-KKKKESS 738
TV QA L+ V G P P +T K +K++D + +E S
Sbjct: 710 VTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEES 769
Query: 739 KELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSF 798
E+ +P +V K+ +++ ++P +R S K
Sbjct: 770 DSEEAAASPAQV------KTSVKKT-----------QAKANPAAARAPSAKG-------- 804
Query: 799 TDNAPSPSIGGSSRLENTTPTQPLTPLH------VVTQNGAEASSV--KTNSPAYSDISD 850
T +AP + +++ + +P++ P+ V+ + A SV + A +
Sbjct: 805 TISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGP 864
Query: 851 AGEDGEGKVDSVKSKDAEQLVK---EGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSS 907
+ G + +S ++AE L + G + +K+SP A +
Sbjct: 865 EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESP---------RKGAAPTP 915
Query: 908 PGALNPS-SQAGVESQALKTKRDEEPE 933
PG PS +QAG + + + + + +
Sbjct: 916 PGKTGPSAAQAGKQDDSGSSSEESDSD 942
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 47.4 bits (111), Expect = 1e-04
Identities = 170/895 (18%), Positives = 297/895 (33%), Gaps = 160/895 (17%)
Query: 376 RPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPP-ASSTSEDVKAS- 433
+P +P + A D K GS ++ +PP A S S+
Sbjct: 678 QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737
Query: 434 PSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPV 493
PS +++ P++D + + K + + ++S + +P +KV+ ++ P P+
Sbjct: 738 PSVPSEQDKAPVAD-DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PL 795
Query: 494 LIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASV 553
D P+ Q+ T + P DS+ P + + S G S
Sbjct: 796 KTDSAKPS--------------QSFPPTGEKVSPF---DSKAIPRPASDSKIISHPGPSS 838
Query: 554 SQKGS--LSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDD 611
KG + P + + SP P +K KG +
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG-------------------SPTPP 879
Query: 612 GPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQ----Q 667
GP T+ + ++ +E+ ++ S + S+ A P P + +
Sbjct: 880 GPR---PTAGQTVPTPQQSPKPQEQSRRFS------LNLGSITDAPKSQPTTPQETVTGK 930
Query: 668 IYTFQTATFTAASPG-SSSGLTATVAQAMPNSPQLK---PIQPKPTVMGEPFTVNPAL-T 722
++ F + F+ AS S++G +Q+ P +P + P QP PT G P + A
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP-PTSQGPPKSTGQAPPA 989
Query: 723 PAKDKKKKDKKKKESSKELES------------------PLTPGKVCRAEEGK------- 757
PAK K + K ++++LE P+ K AE K
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 758 --SPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSF----------------- 798
SP ES+ K E + P+ + K + + F
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Query: 799 -TDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEG 857
T A S +G ++ +P+ V T E+SS KT P + E
Sbjct: 1110 QTQRAISGQLGDIRKMPPAPSGPKASPMPVPT----ESSSQKTAVPPQVKLVKKQEQ--- 1162
Query: 858 KVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQA 917
VK+ +AE+++ E K+TL K P + + AL
Sbjct: 1163 ---EVKT-EAEKVILEKVKETL----SMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL 1214
Query: 918 GVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQY 977
E + + E E I + K + EEKKP P P L +Q
Sbjct: 1215 PEEKKLIP-----EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQV 1269
Query: 978 AYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALK 1037
L A + E +Q + +E G+ L + +
Sbjct: 1270 QIA-----------EEKLEGRVAPKTVQEGKQPQTKME----GLPSGTPQSLPKEDDKTT 1314
Query: 1038 EEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPEGL 1097
+ K++P PP K + PGK K D K D SS ++P+GL
Sbjct: 1315 KTIKEQPQ-PPCTAKPDQVE------PGKEKTEKED-------DKSDTSSSQQPKSPQGL 1360
Query: 1098 KVKLSDASHLSKEASEAKT-----GAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDI 1152
+ +S E + + + + D + P + S +
Sbjct: 1361 SDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSIL 1420
Query: 1153 KSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESRLGSKEPR 1207
+++ +E+ K + S + ++ +S S ++ SEE S+E R
Sbjct: 1421 EAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEER 1475
Score = 47.0 bits (110), Expect = 1e-04
Identities = 154/735 (20%), Positives = 256/735 (34%), Gaps = 94/735 (12%)
Query: 632 MEKEKCKKPSSLKPEKIPSKSLKS-ARPIAPAIPPQQIYTFQTATFTAAS--PGSSS--- 685
+ K ++P ++KP P + K A+P+ PA PP Q QT + +S PG +
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ----QTGSEKPSSEQPGPKALAQ 393
Query: 686 --GLTATVAQAM-PNSPQLKPI-QPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKEL 741
G+ T AQ P P + + PKP +P +PA P K ++ K
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ-QPGLQSPAKAPG--PTKTPVQQPGPGKIP 450
Query: 742 ESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDN 801
PGK + G + K G + P + S K + + S
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS---T 507
Query: 802 APSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSP----AYSDISDAGEDGEG 857
P P G ++ +P QP + Q G+ S + SP A + G G
Sbjct: 508 KPPPQQPGPAK---PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 858 K--VDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGAL---- 911
K S A+Q +G KT+ P ++ + ++ + + Q++ +L
Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624
Query: 912 -NPSSQAGVE--------SQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQ 962
NP E +AL P S + K+K SS Q
Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684
Query: 963 QRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVD 1022
++ Q L PP + H S + +Q E + ++ V
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHG---SPSAKAKQPPEADSLSKPAPPKEPSVP 741
Query: 1023 KKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKE--PGA---DPAKS 1077
+ +++ ++ KQ + PT TDLV S K P + A+
Sbjct: 742 SE-----QDKAPVADDKPKQPKMVKPT-------TDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 1078 VIIPKLDDSSKLPGQA--PEGLKVKLSDASHLSKEASEAK------TGAECGRQAEMDPI 1129
P L S P Q+ P G KV D+ + + AS++K +E Q ++DP+
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 1130 LWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSS 1189
+++ EP K + + D K + S + G+ +
Sbjct: 850 ---QKKEEP--------------KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 1190 DCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYS-QSYDPNHPSYRSMP 1248
E+SR S P S P T ++ + G+ S S N S P
Sbjct: 893 QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP 952
Query: 1249 AVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASP----SVTCKSSSESKALDILQQ 1304
Q+ PG+ P + +P S G +A P S+ K +++ A + L+
Sbjct: 953 GPHSQSGPGA--PMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010
Query: 1305 HASHYKSKSPTISDK 1319
A + T ++K
Sbjct: 1011 KAEQAPTVKRTETEK 1025
Score = 32.3 bits (72), Expect = 3.3
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 13/125 (10%)
Query: 640 PSSLKPEKIPSKSLKSARPIAPAIPP-QQIYTFQTATFTAASPGSSSGLTATVAQAMPNS 698
P+S KP +P K L A P+ A P + T +T ++ + + T +P
Sbjct: 2430 PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK 2489
Query: 699 PQL---------KPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGK 749
P +P KP + +P V P L P +K D K + L S +T
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKP--VIPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNL 2546
Query: 750 VCRAE 754
V A+
Sbjct: 2547 VTSAD 2551
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 47.4 bits (111), Expect = 1e-04
Identities = 170/895 (18%), Positives = 297/895 (33%), Gaps = 160/895 (17%)
Query: 376 RPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPP-ASSTSEDVKAS- 433
+P +P + A D K GS ++ +PP A S S+
Sbjct: 678 QPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE 737
Query: 434 PSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPV 493
PS +++ P++D + + K + + ++S + +P +KV+ ++ P P+
Sbjct: 738 PSVPSEQDKAPVAD-DKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP-PL 795
Query: 494 LIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASV 553
D P+ Q+ T + P DS+ P + + S G S
Sbjct: 796 KTDSAKPS--------------QSFPPTGEKVSPF---DSKAIPRPASDSKIISHPGPSS 838
Query: 554 SQKGS--LSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDD 611
KG + P + + SP P +K KG +
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKG-------------------SPTPP 879
Query: 612 GPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQ----Q 667
GP T+ + ++ +E+ ++ S + S+ A P P + +
Sbjct: 880 GPR---PTAGQTVPTPQQSPKPQEQSRRFS------LNLGSITDAPKSQPTTPQETVTGK 930
Query: 668 IYTFQTATFTAASPG-SSSGLTATVAQAMPNSPQLK---PIQPKPTVMGEPFTVNPAL-T 722
++ F + F+ AS S++G +Q+ P +P + P QP PT G P + A
Sbjct: 931 LFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQP-PTSQGPPKSTGQAPPA 989
Query: 723 PAKDKKKKDKKKKESSKELES------------------PLTPGKVCRAEEGK------- 757
PAK K + K ++++LE P+ K AE K
Sbjct: 990 PAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049
Query: 758 --SPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSF----------------- 798
SP ES+ K E + P+ + K + + F
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNC 1109
Query: 799 -TDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEG 857
T A S +G ++ +P+ V T E+SS KT P + E
Sbjct: 1110 QTQRAISGQLGDIRKMPPAPSGPKASPMPVPT----ESSSQKTAVPPQVKLVKKQEQ--- 1162
Query: 858 KVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQA 917
VK+ +AE+++ E K+TL K P + + AL
Sbjct: 1163 ---EVKT-EAEKVILEKVKETL----SMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL 1214
Query: 918 GVESQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQY 977
E + + E E I + K + EEKKP P P L +Q
Sbjct: 1215 PEEKKLIP-----EEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQV 1269
Query: 978 AYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALK 1037
L A + E +Q + +E G+ L + +
Sbjct: 1270 QIA-----------EEKLEGRVAPKTVQEGKQPQTKME----GLPSGTPQSLPKEDDKTT 1314
Query: 1038 EEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPEGL 1097
+ K++P PP K + PGK K D K D SS ++P+GL
Sbjct: 1315 KTIKEQPQ-PPCTAKPDQVE------PGKEKTEKED-------DKSDTSSSQQPKSPQGL 1360
Query: 1098 KVKLSDASHLSKEASEAKT-----GAECGRQAEMDPILWYRQEAEPRMWTYVYPAKYSDI 1152
+ +S E + + + + D + P + S +
Sbjct: 1361 SDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSIL 1420
Query: 1153 KSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSSDCKLPTSEESRLGSKEPR 1207
+++ +E+ K + S + ++ +S S ++ SEE S+E R
Sbjct: 1421 EAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEER 1475
Score = 47.0 bits (110), Expect = 1e-04
Identities = 154/735 (20%), Positives = 256/735 (34%), Gaps = 94/735 (12%)
Query: 632 MEKEKCKKPSSLKPEKIPSKSLKS-ARPIAPAIPPQQIYTFQTATFTAAS--PGSSS--- 685
+ K ++P ++KP P + K A+P+ PA PP Q QT + +S PG +
Sbjct: 338 LTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ----QTGSEKPSSEQPGPKALAQ 393
Query: 686 --GLTATVAQAM-PNSPQLKPI-QPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKEL 741
G+ T AQ P P + + PKP +P +PA P K ++ K
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ-QPGLQSPAKAPG--PTKTPVQQPGPGKIP 450
Query: 742 ESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDN 801
PGK + G + K G + P + S K + + S
Sbjct: 451 AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS---T 507
Query: 802 APSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSP----AYSDISDAGEDGEG 857
P P G ++ +P QP + Q G+ S + SP A + G G
Sbjct: 508 KPPPQQPGPAK---PSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSG 564
Query: 858 K--VDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGAL---- 911
K S A+Q +G KT+ P ++ + ++ + + Q++ +L
Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624
Query: 912 -NPSSQAGVE--------SQALKTKRDEEPESIEGKVKNDICEEKKPELSSSSQQPSVIQ 962
NP E +AL P S + K+K SS Q
Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSP 684
Query: 963 QRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVD 1022
++ Q L PP + H S + +Q E + ++ V
Sbjct: 685 KKDAAPKQDLSKAPEPKKPPPLVKQPTLHG---SPSAKAKQPPEADSLSKPAPPKEPSVP 741
Query: 1023 KKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKE--PGA---DPAKS 1077
+ +++ ++ KQ + PT TDLV S K P + A+
Sbjct: 742 SE-----QDKAPVADDKPKQPKMVKPT-------TDLVSSSSATTKPDIPSSKVQSQAEE 789
Query: 1078 VIIPKLDDSSKLPGQA--PEGLKVKLSDASHLSKEASEAK------TGAECGRQAEMDPI 1129
P L S P Q+ P G KV D+ + + AS++K +E Q ++DP+
Sbjct: 790 KTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPV 849
Query: 1130 LWYRQEAEPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSS 1189
+++ EP K + + D K + S + G+ +
Sbjct: 850 ---QKKEEP--------------KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTP 892
Query: 1190 DCKLPTSEESRLGSKEPRPSVHVPVSSPLTQHQSYIPYMHGYSYS-QSYDPNHPSYRSMP 1248
E+SR S P S P T ++ + G+ S S N S P
Sbjct: 893 QQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQP 952
Query: 1249 AVMMQNYPGSYLPSSYSFSPYGSKVSGGEDADKARASP----SVTCKSSSESKALDILQQ 1304
Q+ PG+ P + +P S G +A P S+ K +++ A + L+
Sbjct: 953 GPHSQSGPGA--PMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEP 1010
Query: 1305 HASHYKSKSPTISDK 1319
A + T ++K
Sbjct: 1011 KAEQAPTVKRTETEK 1025
Score = 32.3 bits (72), Expect = 3.3
Identities = 32/125 (25%), Positives = 49/125 (39%), Gaps = 13/125 (10%)
Query: 640 PSSLKPEKIPSKSLKSARPIAPAIPP-QQIYTFQTATFTAASPGSSSGLTATVAQAMPNS 698
P+S KP +P K L A P+ A P + T +T ++ + + T +P
Sbjct: 2430 PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK 2489
Query: 699 PQL---------KPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGK 749
P +P KP + +P V P L P +K D K + L S +T
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKP--VIPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNL 2546
Query: 750 VCRAE 754
V A+
Sbjct: 2547 VTSAD 2551
>gi|91982772 mucin 17 [Homo sapiens]
Length = 4493
Score = 46.6 bits (109), Expect = 2e-04
Identities = 114/544 (20%), Positives = 197/544 (36%), Gaps = 74/544 (13%)
Query: 335 NKTYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKG 394
+KT V T + + +PP PT+++ G+R P ++ PV T AS
Sbjct: 1187 SKTQVATSTEAS----SPP-----PTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEAS 1237
Query: 395 TSNSS----KTRAGANSKGRRGSQNSSEHRPPASSTSED---VKASPSSANKRKNKPLSD 447
T ++S T +++ + P S+TSE + + P S + S
Sbjct: 1238 TLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEAS- 1296
Query: 448 MELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYK 507
L ++ D+KG V +N + S+ P GT + PT +P L P
Sbjct: 1297 -TLLTTPVDTKGPV-VTSNEVSSSPTPAEGTSM-PTSTYSEGRTP-LTSIPVNTTLVASS 1352
Query: 508 HINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSL---SPARS 564
I+ L T + EA C+ + S+ S+ +P+
Sbjct: 1353 AISILSTTPVDNSTPVTTSTEA------------------CSSPTTSEGTSMPNSNPSEG 1394
Query: 565 ATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAF 624
TP + +P SS+ ST S G T A S+ + +G S+ T ++
Sbjct: 1395 TTPLTSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGK 1454
Query: 625 DSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSS 684
L+ P S P S S P+ P T+T ++SP +
Sbjct: 1455 TPLK---------SIPVSNTPVANSEASTLSTTPVDSNSP------VVTSTAVSSSPTPA 1499
Query: 685 SGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESP 744
G + ++ S L I T + + + TPA + SS +
Sbjct: 1500 EGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTAD 1559
Query: 745 LTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPS 804
T + EG +P + + +L SS+ + I ++ ++ + T+ + S
Sbjct: 1560 GTSMQTSTYSEGSTPL-----TSLPVSTMLVVSSEANTLSTTPIDSKT-QVTASTEASSS 1613
Query: 805 PSIGGSSRLENT----TPTQPLTPLHVVTQNGAEASSVKT-----NSPAY--SDISDAGE 853
+ GSS +T +P P+ EAS++ T NSP +++S +
Sbjct: 1614 TTAEGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPT 1673
Query: 854 DGEG 857
EG
Sbjct: 1674 PAEG 1677
Score = 42.7 bits (99), Expect = 0.002
Identities = 150/801 (18%), Positives = 267/801 (33%), Gaps = 124/801 (15%)
Query: 379 SNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSAN 438
S TPV+ + S GTS+S T G++ + S+ P + + S A+
Sbjct: 2654 STTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERST---PLTNILVSTTLLANSEAS 2710
Query: 439 KRKNKPL-------SDMELNSSSEDSKG-SKRVRTNSMGSATGPLPGTKVEPTVLDRNCP 490
P+ + E +SS ++G S R+ T S GS PL V + +
Sbjct: 2711 TLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGST--PLTSILVSTLPVASSEA 2768
Query: 491 SPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNG 550
S V + T D+ +E P
Sbjct: 2769 STV-------------------------STTAVDTSIPVTTSTEASSSPTT--------- 2794
Query: 551 ASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSD 610
A V+ + +P+ ++TP + H+P SS+ T S T A S+ +
Sbjct: 2795 AEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTA 2854
Query: 611 DGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYT 670
+G V T+++ L P S P S S P+ +IP
Sbjct: 2855 EGIVVPISTASEGSTLL---------TSIPVSTTPVASSEASTLSTTPVDTSIP------ 2899
Query: 671 FQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKDKKKK 730
T+T ++SP ++ G + ++ S L I + + TP +
Sbjct: 2900 VTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPV 2959
Query: 731 DKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKA 790
+ SS + T + E ++P S M + + S L+ A
Sbjct: 2960 TTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPV-------ASSEASTLSRTPA 3012
Query: 791 E-ADKIYSFTDNAPSPSIGGSSRLENTTPTQ---PLTPLHVVTQNGA--EASSVKT---- 840
+ + + + T+ + SP+ + + +TP++ PLT + V T A EAS++ T
Sbjct: 3013 DTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVD 3072
Query: 841 -NSPAY--SDISDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFP----------PQPQSK 887
NSP +++S + EG + + G + P P
Sbjct: 3073 SNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDT 3132
Query: 888 DSPYYQGFESYYSPSYAQ------SSPG-ALNPSSQAGVESQALKTKRDEEPESIEGKVK 940
+P E++ SP+ ++ S+P P + V + + + D +
Sbjct: 3133 STPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTS 3192
Query: 941 NDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTA 1000
+ + S++++ S+ P+ M L + P T + +NT
Sbjct: 3193 TPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTP 3252
Query: 1001 YRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIP-PTLTKAPSLTDL 1059
E + E G + E S+P T T A S T
Sbjct: 3253 LTTSTEASSSPPTAE------------GTSMPTSTPSEGSTPLTSMPVSTTTVASSETST 3300
Query: 1060 VKSGPGKAKEPGADPAKSVIIPKLDDSSKLP------GQAP------EGLKVKLSDASHL 1107
+ + P P +++ P + D + +P G P V S+AS L
Sbjct: 3301 LSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360
Query: 1108 SKEASEAKTGAECGRQAEMDP 1128
S + T +A + P
Sbjct: 3361 STTPVDTSTPVTTSTEASLSP 3381
Score = 40.0 bits (92), Expect = 0.016
Identities = 161/840 (19%), Positives = 274/840 (32%), Gaps = 105/840 (12%)
Query: 76 TPVPGPQGKEGKSK-------SKRSKSGKDTSKPTPG----TSLFTPSEGAA-------S 117
T P EG S S ++ + + + P G T+L SEG S
Sbjct: 2012 TSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDS 2071
Query: 118 KKEV----QGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSE 173
K +V + S A + + +GS S + ++ S + + +
Sbjct: 2072 KTQVTNSTEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNS 2131
Query: 174 GVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNPLGTKP--- 230
V T +E P+P G Q + T S + +A++ L T P
Sbjct: 2132 PVITSTEVSSS---PIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDT 2188
Query: 231 -EPEEGENECRLLKKVKSEKMESPVSTPAV-------LPIHLLVPVVNNDISSPCEQIMV 282
P E R SE P STP+ +P+ + PVV ++ S+ +
Sbjct: 2189 STPVTNSTEARS-SPTTSEGTSMPTSTPSEGSTPFTSMPVSTM-PVVTSEAST------L 2240
Query: 283 RTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNKTYVGTL 342
V +T V +TE GTS+ + T + V+ T + V TL
Sbjct: 2241 SATPVDTST-PVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTL 2299
Query: 343 LDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNE---TATASDSKGTSNSS 399
P +S G NTP+ + T S TS S
Sbjct: 2300 STTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS 2359
Query: 400 KTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKG 459
T A ++ SQ S S T+ D + P+S + PL+ + +++ S
Sbjct: 2360 TTPADTSTPVTTYSQAGS------SPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVVSSE 2413
Query: 460 SKRVRTNSMGSATGPLPGTKV-------EPTVLDRNCPSP---VLIDCPHPNCNKKYKHI 509
+ T + ++T T+ E T + + PS L P
Sbjct: 2414 ASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEA 2473
Query: 510 NGLKYHQAHAHTDDDSKPEADGDSEYGEE---PILHADLGSCNGASV-----------SQ 555
L T + EA E+ PI A GS S+ +
Sbjct: 2474 GTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAS 2533
Query: 556 KGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSV 615
S +P S +P V E S + S++ ++ EG T L ++ S
Sbjct: 2534 TLSTTPVDSNSPVVTSTEISSSATSAEGTSM---PTSTYSEGSTPLRSMPVSTKPLASSE 2590
Query: 616 MDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKS-----------LKSARPIAPA-- 662
S D+ E P++ K +P + L S P+A +
Sbjct: 2591 ASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEA 2650
Query: 663 -----IPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTV 717
P T+T T++SP ++ G + + S L I T++
Sbjct: 2651 STLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTNILVSTTLLANSEAS 2710
Query: 718 NPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGS 777
+ TP + SS + T ++ +G +P + + L S
Sbjct: 2711 TLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPL-----TSILVSTLPVAS 2765
Query: 778 SDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASS 837
S+ ++ + + T+ + SP+ + + +TP++ TPL + N +S
Sbjct: 2766 SEASTVSTTAVDTSI-PVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVAS 2824
Score = 39.7 bits (91), Expect = 0.021
Identities = 92/480 (19%), Positives = 172/480 (35%), Gaps = 61/480 (12%)
Query: 377 PNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSS 436
P +N PV+ S T+ S T A +N+ S+ SS SST+ + + P+S
Sbjct: 571 PLTNMPVSTRLVVSSEASTT--STTPADSNTFVTTSSEASS------SSTTAEGTSMPTS 622
Query: 437 ANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKV---EPTVLDRNCPSPV 493
+ ++ M ++++ S + + T + S T T+ T + P+
Sbjct: 623 TYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTST 682
Query: 494 LIDCPHPNCNKKYKHINGLKYHQAHAHTDD----DSKPEADGDSEYGEEPILHADLGSCN 549
+ P + +N + A T D+ +E P + +
Sbjct: 683 YTEGSTPLTSMP---VNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPT------TAD 733
Query: 550 GASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGS 609
GAS+ +P+ +TP + + SS+ ST S T A + +
Sbjct: 734 GASMPTS---TPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTT 790
Query: 610 DDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPI---APAIPPQ 666
+G S+ T ++ L P S+ P P S S P+ +P
Sbjct: 791 TEGTSMPISTPSEGSPLLT---------SIPVSITPVTSPEASTLSTTPVDSNSPVTTST 841
Query: 667 QIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTPAKD 726
++ + T + P S+ T +MP S L T+ P + +T + +
Sbjct: 842 EVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTE 901
Query: 727 KKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLA 786
+ + +S TPG EG +P + S ++ A
Sbjct: 902 ARSSPTTSEGTSMPTS---TPG------EGSTPLTSMPDSTTPVV------SSEARTLSA 946
Query: 787 SIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPL------HVVTQNGAEASSVKT 840
+ + + + T+ SP+ + + +TP++ TPL H + N +EAS++ T
Sbjct: 947 TPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVAN-SEASTLST 1005
Score = 38.5 bits (88), Expect = 0.046
Identities = 107/592 (18%), Positives = 195/592 (32%), Gaps = 80/592 (13%)
Query: 377 PNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSS 436
P S TPV ++ AS+ T SKT+ +++ + + P S+ SE ++P +
Sbjct: 458 PVSTTPV-ASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEG--STPLT 514
Query: 437 ANKRKNKPLSDMELNS-SSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLI 495
+ P++ E ++ S+ S V T+S S++ P PT +P L
Sbjct: 515 SMSVSTMPVASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTP-LT 573
Query: 496 DCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQ 555
+ P + A ++T + EA S E + S G +++
Sbjct: 574 NMPVSTRLVVSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITS 633
Query: 556 KG--------------SLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDL 601
S +P S TP E S S +++ ++ EG T L
Sbjct: 634 MSVSTTLVASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSM---PTSTYTEGSTPL 690
Query: 602 GALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKS--------- 652
++ + + S S D+ E P++ +P+ +
Sbjct: 691 TSMPVNTTLVASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLT 750
Query: 653 --------LKSARPIAPAIPPQQIYT-FQTATFTAASPGSSSGLTATVAQAMPNSPQLKP 703
L S+ + P T T+T + SP ++ G + ++ SP L
Sbjct: 751 SMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTS 810
Query: 704 IQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRE- 762
I T + P + TP + SS + T EG++P
Sbjct: 811 IPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSM 870
Query: 763 ----------------------SSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTD 800
S+ E + ++ S S E +
Sbjct: 871 PVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMP 930
Query: 801 NAPSPSIGGSSRLENTTPTQPLTPLHVVTQ-----NGAEASSVKTNSPAYSDISDAGEDG 855
++ +P + +R + TP TP+ T+ AE +S+ T++P+
Sbjct: 931 DSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTPS----------- 979
Query: 856 EGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSS 907
EG + + LV TL P ++P E+ P A+ +
Sbjct: 980 EGTTPLTSTPVSHTLVANSEASTL-STTPVDSNTPLTTSTEASSPPPTAEGT 1030
Score = 38.5 bits (88), Expect = 0.046
Identities = 167/867 (19%), Positives = 289/867 (33%), Gaps = 87/867 (10%)
Query: 59 IPAPNAVATLPD-NIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTP--GTSLFTP--SE 113
IP + T P+ + TPV +K S + +S PTP GTS+ T SE
Sbjct: 1283 IPVSTTLVTSPEASTLLTTPVD--------TKGPVVTSNEVSSSPTPAEGTSMPTSTYSE 1334
Query: 114 GAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSE 173
G + + A++ + + P + S S E +S + SE
Sbjct: 1335 GRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNP-SE 1393
Query: 174 GVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTG-----AVEPLGSIAIEPGAALNPLGT 228
G + + P+ + VDT + E S G ++ P T
Sbjct: 1394 GTTPLTSIP---VSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISI-PTST 1449
Query: 229 KPEPEEGENECRLLKKVKSEKMESPVSTPAVLPIHLLVPVVNNDISS----PCE--QIMV 282
P EG+ + + + S ST + P+ PVV + S P E I +
Sbjct: 1450 ---PSEGKTPLKSIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAI 1506
Query: 283 RTRSVGVNTCDVALATEPECLGPCEPGTSVNLEGIVWQETEDGMLVVNVTWRNK------ 336
T S G AL + P T+V I T + VT ++
Sbjct: 1507 STPSEG----STALTSIPVST------TTVASSEINSLSTTPAVTSTPVTTYSQASSSPT 1556
Query: 337 TYVGTLLDCTRHDWAPPRFCDSPTSDLEMRNGRGRGKRMRP-NSNTPVNETATASDSKGT 395
T GT + + + P S + + + P +S T V + AS S
Sbjct: 1557 TADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPIDSKTQVTASTEASSSTTA 1616
Query: 396 SNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSE 455
SS T + + + P AS + + +P +N + ++ E++SS
Sbjct: 1617 EGSSMTISTPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSN---SPVITSTEVSSSPT 1673
Query: 456 DSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYH 515
++G+ + T++ PL V T + + S L P N
Sbjct: 1674 PAEGTS-MPTSTYTEGRTPLTSITVRTTPVASSAIS-TLSTTPVDNSTPVTTSTEARSSP 1731
Query: 516 QAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPH 575
T + ++G + P+ + S +++S +P ++TP E
Sbjct: 1732 TTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSA----TPIDTSTPVTTSTEAT 1787
Query: 576 SPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKE 635
S SP++ T EG T L + + S S DS
Sbjct: 1788 S-SPTTAEGTS--IPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTA 1844
Query: 636 KCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAM 695
P+ + I + + +IP + T T ++ + + T +
Sbjct: 1845 VSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQV 1904
Query: 696 PNSPQLKPIQPKPTVMGEPFTVNPALT--PAKDKKKKDKKKKESSKELESPLTPGKVCRA 753
+SP PT P P LT P + S L TP V
Sbjct: 1905 SSSPTTADGSSMPT--STPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTP--VTTY 1960
Query: 754 EEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLAS---IKAEADKIYSF-----------T 799
+ S + G M GS+ L++ + +EA + + T
Sbjct: 1961 SQASSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTST 2020
Query: 800 DNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKV 859
+ + SP+ G + ++ +TP++ TPL G S+ S + +S D + +V
Sbjct: 2021 EGSSSPTTAGGTSIQTSTPSERTTPL-----AGMPVSTTLVVSSEGNTLSTTPVDSKTQV 2075
Query: 860 DSVKSKDAEQLVKEGAKKTLFPPQPQS 886
+ ++ + EG+ T+ P S
Sbjct: 2076 TN-STEASSSATAEGSSMTISAPSEGS 2101
Score = 36.2 bits (82), Expect = 0.23
Identities = 105/506 (20%), Positives = 180/506 (35%), Gaps = 72/506 (14%)
Query: 377 PNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSS 436
P + PV+ T AS TS S T A ++ SQ SS SST+ D + P+S
Sbjct: 1043 PLTRMPVSTTMVASSE--TSTLSTTPADTSTPVTTYSQASS------SSTTADGTSMPTS 1094
Query: 437 ANKRKNKPLSDMELNS----SSEDSKGSKRVRTNSMGSATGPLPG---TKVEPTVLDRNC 489
+ PL+ + +++ SSE S S S+ T T E T + +
Sbjct: 1095 TYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSP 1154
Query: 490 PSP---VLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLG 546
PS L P N L + T DSK + +E P
Sbjct: 1155 PSEGTTPLASMPVSTTLVVSSEANTL------STTPVDSKTQVATSTEASSPPPT----- 1203
Query: 547 SCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSN 606
A V+ + +P +TP + H+P SS+ ST S T S+
Sbjct: 1204 ----AEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSS 1259
Query: 607 DGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKP--SSLKPEKIPSKS-LKSARPIAPAI 663
+ +G S+ T+++ L + P S+L + +K + ++ ++ +
Sbjct: 1260 PTTAEGTSLPTSTTSEGSTLLTSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSP 1319
Query: 664 PPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTVNPALTP 723
P + + T+T+ S G + + V + S + + P P T +
Sbjct: 1320 TPAEGTSMPTSTY---SEGRTPLTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACS 1376
Query: 724 AKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQS 783
+ + + E +PLT V S+ + E ++ S
Sbjct: 1377 SPTTSEGTSMPNSNPSEGTTPLTSIPV------------STTPVVSSEASTLSATPVDTS 1424
Query: 784 RLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQN-----GAEASSV 838
+ AEA SP+ + +TP++ TPL + + +EAS++
Sbjct: 1425 TPGTTSAEA---------TSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTL 1475
Query: 839 KT-----NSPAYSD--ISDAGEDGEG 857
T NSP + +S + EG
Sbjct: 1476 STTPVDSNSPVVTSTAVSSSPTPAEG 1501
Score = 36.2 bits (82), Expect = 0.23
Identities = 88/489 (17%), Positives = 168/489 (34%), Gaps = 42/489 (8%)
Query: 379 SNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSAN 438
S TPV+ + ++S +S T G + S+ S+ ST V + S+ +
Sbjct: 2182 STTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLS 2241
Query: 439 KRK---NKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLI 495
+ P++ +SS + + T+++ T PL V T++ N L
Sbjct: 2242 ATPVDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLV-ANSEVSTLS 2300
Query: 496 DCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQ 555
P + T + ++G++ P+ + S +++S
Sbjct: 2301 TTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLST 2360
Query: 556 KGSLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSV 615
+PA ++TP + S SP++ T EG T L ++ S
Sbjct: 2361 ----TPADTSTPVTTYSQAGS-SPTTADDTS--MPTSTYSEGSTPLTSVPVSTMPVVSSE 2413
Query: 616 MDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIP-SKSLKSARPIA-------PAI---- 663
S D+ E P++ + IP S + P+A P +
Sbjct: 2414 ASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEA 2473
Query: 664 ------PPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFTV 717
P T+T ++SP ++ + ++ A S L I T + P
Sbjct: 2474 GTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEAS 2533
Query: 718 NPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGS 777
+ TP + SS + T EG +P R M
Sbjct: 2534 TLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLR-------SMPVSTKPL 2586
Query: 778 SDPHQSRLASIKAEAD-KIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQN----- 831
+ S L++ + + + T+ + SP+ + + +TP++ T L + +
Sbjct: 2587 ASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVA 2646
Query: 832 GAEASSVKT 840
+EAS++ T
Sbjct: 2647 SSEASTLST 2655
Score = 32.7 bits (73), Expect = 2.5
Identities = 91/491 (18%), Positives = 177/491 (36%), Gaps = 43/491 (8%)
Query: 374 RMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEHRPP-ASSTSEDVKA 432
R +++TPV + AS S T+ + S+G + P A + +
Sbjct: 3009 RTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLST 3068
Query: 433 SPSSANKRKNKPLSDMELNSSSEDSKG-SKRVRTNSMGSA--TG-PLPGTKVEPTVLDRN 488
+P +N + ++ E++SS ++G S + T S GS TG P+ T V + +
Sbjct: 3069 TPVDSN---SPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTL 3125
Query: 489 CPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSC 548
+PV P + H + ++ S P + G P+ + + +
Sbjct: 3126 STTPVDTSTPVTTSTEA---------HSSPTTSEGTSMPTSTPSE--GSTPLTYMPVSTM 3174
Query: 549 NGASVSQKGSLS--PARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSN 606
S S+ +LS P ++TP E S + + S EG T L ++
Sbjct: 3175 LVVS-SEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIP----TSTPSEGMTPLTSVPV 3229
Query: 607 DGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQ 666
+ S S DS E P + + +P+ + ++P
Sbjct: 3230 SNTPVASSEASILSTTPVDSNTPLTTSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVS 3289
Query: 667 QIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVM---GEPFTVNPALTP 723
+ T T ++ + + T +SP + PT G N + +
Sbjct: 3290 TTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFST 3349
Query: 724 AKDKKKKDKKKKESSKELESPLTPGKVCRAE----EGKSPFRESSGDGMKMEGLLNGSSD 779
+ + + +P+T EG S S +G + S+
Sbjct: 3350 TPVVSSEASTLSTTPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409
Query: 780 PHQSR----LASIKAEADKIYSF-TDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQN--- 831
P S L++ +++ + + T+ + SP+I + L +T ++ TPL ++ +
Sbjct: 3410 PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTP 3469
Query: 832 --GAEASSVKT 840
+EAS++ T
Sbjct: 3470 VASSEASTLST 3480
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 45.8 bits (107), Expect = 3e-04
Identities = 163/816 (19%), Positives = 268/816 (32%), Gaps = 145/816 (17%)
Query: 421 PPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKV 480
PP +S N K P ++ SS + G+ + + G LP
Sbjct: 231 PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290
Query: 481 E---PTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGE 537
P V P P L + + + GL H P A G G
Sbjct: 291 PANFPHVTPNLPPPPALRPLNNASASPP-----GLGAQPLPGHLPS---PHAMGQGMGGL 342
Query: 538 EPILHADLGSCNGASVSQKG-SLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGE 596
P G G +++ SL PA S+ P + P+S S SS
Sbjct: 343 PP------GPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS-------------- 382
Query: 597 GDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSA 656
A S+ S S ++ A S P S P S S +
Sbjct: 383 -----AAASSSSSSSSSSASPFPASQALPSY------------PHSFPPPTSLSVSNQPP 425
Query: 657 RPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFT 716
+ P++P Q +++ P G + A P P P G T
Sbjct: 426 KYTQPSLPSQAVWS------QGPPPPPPYGRLLANSNAHPG--------PFPPSTGAQST 471
Query: 717 VNPALTPAKDKKKKDKKKKESSKELES----------PLTPGKVCRAEEGKS-----PFR 761
+P ++ ++ +++++ ++ + P PG EG S P+
Sbjct: 472 AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYA 531
Query: 762 ESSGDGMKMEGLLNGSSD---PHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTP 818
S G + G + PH S S + N+ S + GS + +P
Sbjct: 532 MSPSLG-SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP 590
Query: 819 TQ-------PLTPLHVVTQNGAEASSV---KTNSPA-YSDISDAGEDGEGKVDSVKSKDA 867
+Q P P+ VT + A S+V +SPA Y S G GK S A
Sbjct: 591 SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK--RAPSPGA 648
Query: 868 EQLVKEGAKKTLFPPQPQSKDSPYYQGFE-----SYYSPSYAQSSPGALNPSSQAGVESQ 922
+ K PP ++ P Y+G + P PG L P+ +G+ S
Sbjct: 649 YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708
Query: 923 ALKTKRDEE-PESIEGKVKNDICEEKK------PELSSSSQQPSVIQQRPNMYMQSLYYN 975
P ++K + EE + P S S P V+ P+ QS +N
Sbjct: 709 PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV-PSHASQSARFN 767
Query: 976 QYAYVPPYGYSDQS----YHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKE 1031
++ G++ + Y L + A ++ ++ R+ EQ+ R ++ +E
Sbjct: 768 KHL---DRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERERERE 824
Query: 1032 REAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPG 1091
+E ++E + + S+ L + G + P P P + S +
Sbjct: 825 KEREREKERELERSVK-----------LAQEGRAPVECPSLGPVPHR--PPFEPGSAVAT 871
Query: 1092 QAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDP------ILWYRQEAEPRMWTYVY 1145
P +L + +T +E R M P +P + Y
Sbjct: 872 VPP-----------YLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNV 920
Query: 1146 PAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKE 1181
PA YS + ER +E R+R L++ + P E
Sbjct: 921 PALYSSDPAAREREREARERDLRDRLKPGFEVKPSE 956
Score = 38.9 bits (89), Expect = 0.035
Identities = 106/524 (20%), Positives = 170/524 (32%), Gaps = 91/524 (17%)
Query: 525 SKPEADGDSEYGEEPILHADLGSCNGASVSQKG---SLSPARSA---TPKVRLVEPHSPS 578
S +DG +E + A + + V+++G +S + S PK E P
Sbjct: 39 STSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPR 98
Query: 579 PSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCK 638
P S L + L+ +G +D + D PS+
Sbjct: 99 PQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIY---------------------- 136
Query: 639 KPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNS 698
P S++ + S L S P P PP + P
Sbjct: 137 SPGSVENDSDSSSGL-SQGPARPYHPP------------------------PLFPPSPQP 171
Query: 699 PQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESP---------LTPGK 749
P P QP+ + F +P++TP + +S+ ++P L PG
Sbjct: 172 PDSTPRQPEAS-----FEPHPSVTPTGYHAPME---PPTSRMFQAPPGAPPPHPQLYPGG 223
Query: 750 VCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGG 809
G + G + G G P + S+ + T +P GG
Sbjct: 224 TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGG 283
Query: 810 S-------SRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSV 862
+ + + TP P P N + + P + G+G
Sbjct: 284 NLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP 343
Query: 863 KSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAG--VE 920
+ + PP S +P + S S S A +S + + SS A
Sbjct: 344 PGPEKGPTLAPSPHS--LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 921 SQALKTKRDEEPESIEGKVKNDICEEKKPELSSS---SQQPSVIQQRPNMYMQSLYYNQY 977
SQAL + P V N + +P L S SQ P P L N
Sbjct: 402 SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP-----PPPPYGRLLANSN 456
Query: 978 AYVPPYGYSD--QSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQR 1019
A+ P+ S QS +ST+ + QQ ++QQ++Q +QQQ+
Sbjct: 457 AHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQ 500
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 45.8 bits (107), Expect = 3e-04
Identities = 163/816 (19%), Positives = 268/816 (32%), Gaps = 145/816 (17%)
Query: 421 PPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTKV 480
PP +S N K P ++ SS + G+ + + G LP
Sbjct: 231 PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290
Query: 481 E---PTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGE 537
P V P P L + + + GL H P A G G
Sbjct: 291 PANFPHVTPNLPPPPALRPLNNASASPP-----GLGAQPLPGHLPS---PHAMGQGMGGL 342
Query: 538 EPILHADLGSCNGASVSQKG-SLSPARSATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGE 596
P G G +++ SL PA S+ P + P+S S SS
Sbjct: 343 PP------GPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSS-------------- 382
Query: 597 GDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPSSLKPEKIPSKSLKSA 656
A S+ S S ++ A S P S P S S +
Sbjct: 383 -----AAASSSSSSSSSSASPFPASQALPSY------------PHSFPPPTSLSVSNQPP 425
Query: 657 RPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEPFT 716
+ P++P Q +++ P G + A P P P G T
Sbjct: 426 KYTQPSLPSQAVWS------QGPPPPPPYGRLLANSNAHPG--------PFPPSTGAQST 471
Query: 717 VNPALTPAKDKKKKDKKKKESSKELES----------PLTPGKVCRAEEGKS-----PFR 761
+P ++ ++ +++++ ++ + P PG EG S P+
Sbjct: 472 AHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYA 531
Query: 762 ESSGDGMKMEGLLNGSSD---PHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLENTTP 818
S G + G + PH S S + N+ S + GS + +P
Sbjct: 532 MSPSLG-SLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSP 590
Query: 819 TQ-------PLTPLHVVTQNGAEASSV---KTNSPA-YSDISDAGEDGEGKVDSVKSKDA 867
+Q P P+ VT + A S+V +SPA Y S G GK S A
Sbjct: 591 SQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK--RAPSPGA 648
Query: 868 EQLVKEGAKKTLFPPQPQSKDSPYYQGFE-----SYYSPSYAQSSPGALNPSSQAGVESQ 922
+ K PP ++ P Y+G + P PG L P+ +G+ S
Sbjct: 649 YKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSL 708
Query: 923 ALKTKRDEE-PESIEGKVKNDICEEKK------PELSSSSQQPSVIQQRPNMYMQSLYYN 975
P ++K + EE + P S S P V+ P+ QS +N
Sbjct: 709 PPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV-PSHASQSARFN 767
Query: 976 QYAYVPPYGYSDQS----YHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKE 1031
++ G++ + Y L + A ++ ++ R+ EQ+ R ++ +E
Sbjct: 768 KHL---DRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERERERE 824
Query: 1032 REAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPG 1091
+E ++E + + S+ L + G + P P P + S +
Sbjct: 825 KEREREKERELERSVK-----------LAQEGRAPVECPSLGPVPHR--PPFEPGSAVAT 871
Query: 1092 QAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDP------ILWYRQEAEPRMWTYVY 1145
P +L + +T +E R M P +P + Y
Sbjct: 872 VPP-----------YLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNV 920
Query: 1146 PAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKE 1181
PA YS + ER +E R+R L++ + P E
Sbjct: 921 PALYSSDPAAREREREARERDLRDRLKPGFEVKPSE 956
Score = 38.9 bits (89), Expect = 0.035
Identities = 106/524 (20%), Positives = 170/524 (32%), Gaps = 91/524 (17%)
Query: 525 SKPEADGDSEYGEEPILHADLGSCNGASVSQKG---SLSPARSA---TPKVRLVEPHSPS 578
S +DG +E + A + + V+++G +S + S PK E P
Sbjct: 39 STSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPR 98
Query: 579 PSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCK 638
P S L + L+ +G +D + D PS+
Sbjct: 99 PQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIY---------------------- 136
Query: 639 KPSSLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNS 698
P S++ + S L S P P PP + P
Sbjct: 137 SPGSVENDSDSSSGL-SQGPARPYHPP------------------------PLFPPSPQP 171
Query: 699 PQLKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESP---------LTPGK 749
P P QP+ + F +P++TP + +S+ ++P L PG
Sbjct: 172 PDSTPRQPEAS-----FEPHPSVTPTGYHAPME---PPTSRMFQAPPGAPPPHPQLYPGG 223
Query: 750 VCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGG 809
G + G + G G P + S+ + T +P GG
Sbjct: 224 TGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGG 283
Query: 810 S-------SRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSV 862
+ + + TP P P N + + P + G+G
Sbjct: 284 NLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP 343
Query: 863 KSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAG--VE 920
+ + PP S +P + S S S A +S + + SS A
Sbjct: 344 PGPEKGPTLAPSPHS--LPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPA 401
Query: 921 SQALKTKRDEEPESIEGKVKNDICEEKKPELSSS---SQQPSVIQQRPNMYMQSLYYNQY 977
SQAL + P V N + +P L S SQ P P L N
Sbjct: 402 SQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPP-----PPPPYGRLLANSN 456
Query: 978 AYVPPYGYSD--QSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQR 1019
A+ P+ S QS +ST+ + QQ ++QQ++Q +QQQ+
Sbjct: 457 AHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQ 500
>gi|40288197 GATA binding protein 6 [Homo sapiens]
Length = 595
Score = 45.4 bits (106), Expect = 4e-04
Identities = 56/214 (26%), Positives = 77/214 (35%), Gaps = 41/214 (19%)
Query: 1213 PVSSPLTQHQSYIPYMHGYSYSQSYDPNHPSYRSMPAVMMQNYPGSYLPSSYSFSPYGSK 1272
PV P T+ S +P G Y + P+ + A +P +S PYGS
Sbjct: 186 PVYVPTTRVGSMLP---GLPYHLQGSGSGPANHAGGAGAHPGWP----QASADSPPYGS- 237
Query: 1273 VSGGEDADKARASPSVTCKSSSESKALDILQQHASHYKSKSPTISDKTSQERDRGGCGVV 1332
GG A A P +++ H S SP+ R+ GG
Sbjct: 238 --GGGAAGGGAAGPGGAGSAAA----------HVSARFPYSPSPPMANGAAREPGGYAAA 285
Query: 1333 GGGGSCSSVGGASG----GERSVDRPRTSPSQRLMSTHHHHHH------------LGYSL 1376
G GG+ GG S G R S ++ L T+HHHHH +G L
Sbjct: 286 GSGGAGGVSGGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHHHHPSPYSPYVGAPL 345
Query: 1377 LPAQYNLPYAAGLSSTAIVASQQGSTPSLYPPPR 1410
PA + AG T ++ S Q + P PR
Sbjct: 346 TPA-----WPAGPFETPVLHSLQSRAGAPLPVPR 374
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 44.7 bits (104), Expect = 6e-04
Identities = 78/344 (22%), Positives = 122/344 (35%), Gaps = 41/344 (11%)
Query: 395 TSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSAN-KRKNKPLSDMELNSS 453
T S RAG R + E PPA +TS +SP A+ + PL L S
Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128
Query: 454 SEDS----KGSKRVRTNSMGS-----ATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNK 504
+E++ K ++ + +++ + +GP PGT P + R+ + + P P +
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPAPSA 187
Query: 505 KYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARS 564
+ T+ K + EP A G + + S S + S
Sbjct: 188 R-----------PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 236
Query: 565 ATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAF 624
ATP L P PS++ + + S L AL P + DA
Sbjct: 237 ATP---LSSPARSGPSARGTPRAPAHP--SQPKPKGLQALR-------PPQVTPPRKDAA 284
Query: 625 DSLERKCMEKEKCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQIYT-FQTATFTAASPGS 683
+L + PS P + P PA PP Q T + T A
Sbjct: 285 PALGP--LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342
Query: 684 SSGLTATVAQAMPNSP---QLKPIQPKPTVMGEPFTVNPALTPA 724
S + +A P +P L P+Q P+ P ++P TP+
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPS 385
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 44.3 bits (103), Expect = 8e-04
Identities = 83/350 (23%), Positives = 126/350 (36%), Gaps = 59/350 (16%)
Query: 394 GTSNSSKTRAGANSKGRRGSQNSSEHRPPASSTSEDVKASPSSAN-KRKNKPLSDMELNS 452
G + S+ T + N R + E PPA +TS +SP A+ + PL L
Sbjct: 78 GPTRSAGT-SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 453 SSEDS----KGSKRVRTNSMGS-----ATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCN 503
S+E++ K ++ + +++ + +GP PGT P + R+ + + P P +
Sbjct: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPAPS 195
Query: 504 KKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPAR 563
+ T+ K + EP A G + + S S +
Sbjct: 196 AR-----------PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
Query: 564 SATPKVRLVEPHSPSPSSKFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDA 623
SATP L P PS++ + + S L AL P + DA
Sbjct: 245 SATP---LSSPARSGPSARGTPRAPAHP--SQPKPKGLQALR-------PPQVTPPRKDA 292
Query: 624 FDSLERKCMEKEKCKKPSSLKPEKIPSKSL---KSARPIAPAIPPQQIYTFQTATFTAAS 680
+L P S P PS S A P PA P T Q AT +
Sbjct: 293 APAL-----------GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA 341
Query: 681 PGSSSGLTATVAQAMPNSPQLKPIQPKPTVMGEP-------FTVNPALTP 723
P S S + Q +P+ P P Q T +G P F +P L+P
Sbjct: 342 PPSPSAPPS--LQTLPSPPATPPSQ-ATTSLGSPTLQATHSFLPSPPLSP 388
Score = 31.2 bits (69), Expect = 7.4
Identities = 32/136 (23%), Positives = 50/136 (36%), Gaps = 14/136 (10%)
Query: 103 TPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKEN 162
TP + GA +K + R AGG+ A P+ + +A + S+
Sbjct: 40 TPAALRVLGAAGAVGRKPLAER------AGGIGGATIPESAPRAGPTRSAGTSSRNPASR 93
Query: 163 SSSKSKKER-------SEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTG-AVEPLGS 214
+ + ER S G + + G +P PLG +G + V G A E
Sbjct: 94 PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 153
Query: 215 IAIEPGAALNPLGTKP 230
A+ GA + G P
Sbjct: 154 SALSAGARRDTSGPTP 169
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 43.5 bits (101), Expect = 0.001
Identities = 109/560 (19%), Positives = 187/560 (33%), Gaps = 81/560 (14%)
Query: 522 DDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHSPSPSS 581
DDD + + + G +P A A S S S + PK + +P +
Sbjct: 135 DDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQ--KPKITPVTV 192
Query: 582 KFSTKGLCKKKLSGEGDTDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKEKCKKPS 641
K TK K + + A S+ S S D++ + K +
Sbjct: 193 KAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEE----------------KAA 236
Query: 642 SLKPEKIPSKSLKSARPIAPAIPPQQIYTFQTATFTAASPGSSSGLTATVAQAMPNSPQL 701
+ + +P K + + P+ A P + +++S SSS Q
Sbjct: 237 ATPKKTVPKKQVVAKAPVKAATTPTRK--------SSSSEDSSSD---------EEEEQK 279
Query: 702 KPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPGKVCRAEEGKSPFR 761
KP++ KP P++ P + KK + + + E + P+ + E S
Sbjct: 280 KPMKNKPG----PYSSVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEE 335
Query: 762 ESSGDGMKMEGLLNGSSDPHQSRLASIKAEADKIYSFTDNAPSPSIGGSSRLEN----TT 817
E + P + S +D S D APS G + N TT
Sbjct: 336 EKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTT 395
Query: 818 PTQPLTPLHVVTQ---NGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEG 874
+ + P Q G + + K +S + + S + E+ + K A K
Sbjct: 396 KSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEE-----EKTKKMVATTKPKAT 450
Query: 875 AKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALNPSSQAGVESQALKTKRDEEPES 934
AK L P Q+ QG S S + SS +S++ V+ + K P
Sbjct: 451 AKAALSLPAKQAP-----QGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSK 505
Query: 935 IEGKVKNDICEEKKPELSSSSQQPSVIQQRPNMYMQSLYYNQYAYVPPYGYSDQSYHTHL 994
K K +SSS S ++ + + P + ++ T
Sbjct: 506 PASAKKG-----KAESSNSSSSDDSSEEEEEKLKGKG---------SPRPQAPKANGTSA 551
Query: 995 LSTNTAYR----QQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAALKEEWKQKPSIPPTL 1050
L+ ++ EE++K+ ++ + G KK + +EA + K K P T
Sbjct: 552 LTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTF 611
Query: 1051 TKAPSLTDLVKSGPGKAKEP 1070
K K G +A P
Sbjct: 612 PKR-------KKGEKRASSP 624
Score = 43.1 bits (100), Expect = 0.002
Identities = 112/523 (21%), Positives = 177/523 (33%), Gaps = 103/523 (19%)
Query: 725 KDKKKKDKKKKESSKELESP-----------------LTPGKVCRAEEGKSPFRESSGDG 767
K KKK E S E E L PGK S ESS D
Sbjct: 77 KAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDD 136
Query: 768 ----MKMEGLLNGSSDPHQSRLASIK----AEADKIYSFTDNAPS---PSIGGSS-RLEN 815
K + + G ++ A K +++D S D P P I + + +
Sbjct: 137 DEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQT 196
Query: 816 TTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDSVKSKDAEQLVKEGA 875
P +P + NG ASS ++S + S SD E+ + K+ +Q+V +
Sbjct: 197 KAPPKPARAAPKIA-NGKAASSSSSSSSSSS--SDDSEEEKAAATPKKTVPKKQVVAKAP 253
Query: 876 KKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSPGALN---------PSSQAGVESQALKT 926
K P +S S E ++ PG + P G +
Sbjct: 254 VKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLGTQPPKKAV 313
Query: 927 KRDEEPESIEGKVKNDIC---EEKKPE----LSSSSQQPSVIQQRPNMYMQSL----YYN 975
++ + ES E EEKKP +S ++ +P ++ S +
Sbjct: 314 EKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSED 373
Query: 976 QYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKAEMGLKEREAA 1035
A P G + S + ++T + + +Q + Q+ + +KA+ E E++
Sbjct: 374 DEAPSKPAGTTKNSSNKPAVTTKSPAVKP--AAAPKQPVGGGQKLLTRKADSSSSEEESS 431
Query: 1036 LKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVIIPKLDDSSKLPGQAPE 1095
EE K K + T KA AK + PAK QAP+
Sbjct: 432 SSEEEKTKKMVATTKPKAT------------AKAALSLPAK---------------QAPQ 464
Query: 1096 GLKVKLSDASHLSKEASEAKTGAE---------CGRQAEMDPILWYRQEAEPRMWTYVYP 1146
G + SD+ S E E KT G A P + +AE
Sbjct: 465 GSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAE--------- 515
Query: 1147 AKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKESTSS 1189
S S + EE + KLK + S + PK +G + ++
Sbjct: 516 ---SSNSSSSDDSSEEEEEKLKGKGS-PRPQAPKANGTSALTA 554
Score = 42.4 bits (98), Expect = 0.003
Identities = 106/556 (19%), Positives = 193/556 (34%), Gaps = 66/556 (11%)
Query: 351 APPRFCDSPTSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGR 410
APP+ S SD + + K +P + T + K + K AN K
Sbjct: 159 APPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKI---ANGKAA 215
Query: 411 RGSQNSSEHRPPASSTSEDVKASPSSANKRKNKPLSDM-------------ELNSSSEDS 457
S +SS +SS+S+D + ++A +K P + +SSSEDS
Sbjct: 216 SSSSSSS-----SSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDS 270
Query: 458 KG-SKRVRTNSMGSATGPLPGTKVEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQ 516
+ + M + GP + P P P P + + Q
Sbjct: 271 SSDEEEEQKKPMKNKPGPY-----------SSVPPP---SAPPPKKSLGTQPPKKAVEKQ 316
Query: 517 AHAHTDDDSKPEADGDSEYGEEPILHADLGSCNGASVSQKGSLSPARSATPKVRLVEPHS 576
+ +DS E+D SE ++P A + K + + ++ + +
Sbjct: 317 QPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEA 376
Query: 577 PSPSSKFSTKGLCKKKLSGEGD-TDLGALSNDGSDDGPSVMDETSNDAFDSLERKCMEKE 635
PS + + K ++ + A G ++ ++ + E E+E
Sbjct: 377 PSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEE 436
Query: 636 KCKKPSSLKPEKIPSKSLKSARPIAPAIPPQQI-YTFQTATFTAASPGSSSGLTATVAQA 694
K KK + K +K+ A ++P +Q + ++ + S S T A
Sbjct: 437 KTKKMVATTKPKATAKA-------ALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSA 489
Query: 695 MPNSPQ-----LKPIQPKPTVMGEPFTVNPALTPAKDKKKKDKKKKESSKELESPLTPG- 748
+ PQ P +P G+ + N + + +++++K K + S ++P G
Sbjct: 490 VKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGT 549
Query: 749 KVCRAEEGKSPFRESSGDGMKMEGLL----NGSSDPHQSRLASIKAE---ADKIYSFTDN 801
A+ GK+ + K + + +GS + A+ +AE A KI T N
Sbjct: 550 SALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPN 609
Query: 802 APSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDISDAGEDGEGKVDS 861
G R +P V + E S ++ + AG+ GE
Sbjct: 610 TFPKRKKGEKRAS--------SPFRRVREEEIEVDSRVADNSFDAKRGAAGDWGERANQV 661
Query: 862 VKSKDAEQLVKEGAKK 877
+K + E KK
Sbjct: 662 LKFTKGKSFRHEKTKK 677
Score = 38.5 bits (88), Expect = 0.046
Identities = 111/513 (21%), Positives = 171/513 (33%), Gaps = 80/513 (15%)
Query: 729 KKDKKKKESSKELESPLTPGKVCRAEEGKSPFRESSGDGMKMEGLLNGSSDPHQSRLASI 788
KK KKK SS +S EE + P + + K GL G + S +S
Sbjct: 76 KKAKKKASSSDSEDSSE------EEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSS 129
Query: 789 KAEADKIYSFTDNAPSPSIGGSSRLENTTPTQPLTPLHVVTQNGAEASSVKTNSPAYSDI 848
+ +D ++ Q P+ + A+A+ P +
Sbjct: 130 EESSD--------------------DDDEEDQKKQPVQKGVKPQAKAAKAP---PKKAKS 166
Query: 849 SDAGEDGEGKVDSVKSKDAEQLVKEGAKKTLFPPQPQSKDSPYYQGFESYYSPSYAQSSP 908
SD+ D + + K++ + +T PP+P G + S S + SS
Sbjct: 167 SDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSS- 225
Query: 909 GALNPSSQAGVESQALKTKRDEEPES---IEGKVKNDICEEKKPELSSSSQQPSVIQQRP 965
SS E +A T + P+ + VK +K S S +Q+
Sbjct: 226 -----SSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKK 280
Query: 966 NMYMQSLYYNQYAYVPPYGYSDQSYHTHLLSTNTAYRQQYEEQQKRQSLEQQQRGVDKKA 1025
M + Y+ VPP L T ++ E+QQ +S E D +
Sbjct: 281 PMKNKP---GPYSSVPPPSAPPPKKS---LGTQPP-KKAVEKQQPVESSEDSSDESDSSS 333
Query: 1026 EMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPA----KSVIIP 1081
E K A+ + KP PP A S +D S + E + PA S P
Sbjct: 334 EEEKKPPTKAVVSKATTKP--PPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKP 391
Query: 1082 KLDDSSKL--PGQAPE---GLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEA 1136
+ S P AP+ G KL S + E + +E + +M + A
Sbjct: 392 AVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATA 451
Query: 1137 EPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGK------------ 1184
+ + PAK + S D + +EE SK +V K+ K
Sbjct: 452 KAAL---SLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPAS 508
Query: 1185 ---------ESTSSDCKLPTSEESRLGSKEPRP 1208
S+SSD EE G PRP
Sbjct: 509 AKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRP 541
Score = 36.2 bits (82), Expect = 0.23
Identities = 52/222 (23%), Positives = 83/222 (37%), Gaps = 18/222 (8%)
Query: 55 KEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGT-----SLF 109
K+V AP AT P + +E + K ++K G +S P P SL
Sbjct: 246 KQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG 305
Query: 110 T-PSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKA--AKASRSVAGSKKEKENSSSK 166
T P + A K++ S D ++ + K KA +KA+ +KK E+SS
Sbjct: 306 TQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDS 365
Query: 167 SKKERSEGVGTCSEKDPGVLQPVPLG-GRGGQYDGSAGVDTGAVEPLGSIAIEPGAALNP 225
S + SE S+ P G + + + AV+P + G
Sbjct: 366 SDSDSSEDDEAPSK---------PAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKL 416
Query: 226 LGTKPEPEEGENECRLLKKVKSEKMESPVSTPAVLPIHLLVP 267
L K + E E ++ K++KM + A L +P
Sbjct: 417 LTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP 458
Score = 33.1 bits (74), Expect = 1.9
Identities = 23/89 (25%), Positives = 36/89 (40%), Gaps = 3/89 (3%)
Query: 88 SKSKRSKSGKDTSKPTPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAA 147
+KS K +P G + +S E + S + +VA PK + KAA
Sbjct: 395 TKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAA 454
Query: 148 ---KASRSVAGSKKEKENSSSKSKKERSE 173
A ++ GS+ +S S S +E E
Sbjct: 455 LSLPAKQAPQGSRDSSSDSDSSSSEEEEE 483
Score = 31.2 bits (69), Expect = 7.4
Identities = 53/247 (21%), Positives = 89/247 (36%), Gaps = 32/247 (12%)
Query: 43 EKDQQKLEMSGSKEVGIPAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKP 102
E D+ + +G+ + P AV T +K P G K ++++ S +
Sbjct: 372 EDDEAPSKPAGTTKNSSNKP-AVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEES 430
Query: 103 TPGTSLFTPSEGAASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKEN 162
+ T A +K + ++ A L A AP+GS ++ S S + ++E++
Sbjct: 431 SSSEEEKTKKMVATTKPKATAKA-----ALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKT 485
Query: 163 SSSKSKKERSEGVGTCSEKDPGVLQPVPLGGRGGQYDGSAGVDTGAVEP---LGSIAIEP 219
S S KK+ + G + P + G+ + S+ D+ E G + P
Sbjct: 486 SKSAVKKKPQKVAGGAAPSKPASAKK----GKAESSNSSSSDDSSEEEEEKLKGKGSPRP 541
Query: 220 GA----------ALNPLGTKPEPEEGENECRL---------LKKVKSEKMESPVSTPAVL 260
A A N K EE E + + LKK K + TP
Sbjct: 542 QAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAK 601
Query: 261 PIHLLVP 267
I L P
Sbjct: 602 KIKLQTP 608
>gi|169166609 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 6 [Homo sapiens]
Length = 305
Score = 43.1 bits (100), Expect = 0.002
Identities = 47/209 (22%), Positives = 90/209 (43%), Gaps = 12/209 (5%)
Query: 360 TSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEH 419
+S+ + + R +R + ++ ++++ S G+S S+ + +G++S +S+
Sbjct: 52 SSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSS-------SSASS 104
Query: 420 RPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTK 479
R +SSTS +S SS + ++ D S S+ SK KR + P P TK
Sbjct: 105 RSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK-SKPPKRDEKERKRRSPSPKP-TK 162
Query: 480 VEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEP 539
V L RN +++ + K K I+ + + H H + + E+
Sbjct: 163 VHIGRLTRNVTKDHIMEI--FSTYGKIKMID-MPVERMHPHLSKGYACVEFENPDEAEKA 219
Query: 540 ILHADLGSCNGASVSQKGSLSPARSATPK 568
+ H D G +G ++ L+P TP+
Sbjct: 220 LKHMDGGQIDGQEITATVVLAPWPRPTPR 248
Score = 35.4 bits (80), Expect = 0.39
Identities = 27/117 (23%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 58 GIPAPNAVATLPDNIKFVTPVPGP------QGKEGKSKSKRSKSGKDTSKPTPGTSLFTP 111
G+ + + +N K T P P ++ K +SK + K++S+ G
Sbjct: 5 GVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRK 64
Query: 112 SEGAAS-KKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKS 167
A+S + RS +++G + + GS ++ +SRS + S +SSS S
Sbjct: 65 RRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
Score = 33.5 bits (75), Expect = 1.5
Identities = 44/169 (26%), Positives = 61/169 (36%), Gaps = 26/169 (15%)
Query: 1020 GVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVI 1079
GV KK+ +G+KE +K S T+APS T K+K+ D +
Sbjct: 5 GVKKKSLLGVKENN--------KKSS-----TRAPSPTKRKDRSDEKSKDRSKDKGATKE 51
Query: 1080 IPKLD---DSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEA 1136
+ D D ++ A G S +S S S TG+ G + A
Sbjct: 52 SSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSS---------SA 102
Query: 1137 EPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKE 1185
R + ++ S S R R RSRSK PK D KE
Sbjct: 103 SSRSGSSS-TSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKE 150
>gi|113415994 PREDICTED: similar to ribonucleic acid binding protein
S1 isoform 2 [Homo sapiens]
Length = 305
Score = 43.1 bits (100), Expect = 0.002
Identities = 47/209 (22%), Positives = 90/209 (43%), Gaps = 12/209 (5%)
Query: 360 TSDLEMRNGRGRGKRMRPNSNTPVNETATASDSKGTSNSSKTRAGANSKGRRGSQNSSEH 419
+S+ + + R +R + ++ ++++ S G+S S+ + +G++S +S+
Sbjct: 52 SSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSS-------SSASS 104
Query: 420 RPPASSTSEDVKASPSSANKRKNKPLSDMELNSSSEDSKGSKRVRTNSMGSATGPLPGTK 479
R +SSTS +S SS + ++ D S S+ SK KR + P P TK
Sbjct: 105 RSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSK-SKPPKRDEKERKRRSPSPKP-TK 162
Query: 480 VEPTVLDRNCPSPVLIDCPHPNCNKKYKHINGLKYHQAHAHTDDDSKPEADGDSEYGEEP 539
V L RN +++ + K K I+ + + H H + + E+
Sbjct: 163 VHIGRLTRNVTKDHIMEI--FSTYGKIKMID-MPVERMHPHLSKGYACVEFENPDEAEKA 219
Query: 540 ILHADLGSCNGASVSQKGSLSPARSATPK 568
+ H D G +G ++ L+P TP+
Sbjct: 220 LKHMDGGQIDGQEITATVVLAPWPRPTPR 248
Score = 35.4 bits (80), Expect = 0.39
Identities = 27/117 (23%), Positives = 50/117 (42%), Gaps = 7/117 (5%)
Query: 58 GIPAPNAVATLPDNIKFVTPVPGP------QGKEGKSKSKRSKSGKDTSKPTPGTSLFTP 111
G+ + + +N K T P P ++ K +SK + K++S+ G
Sbjct: 5 GVKKKSLLGVKENNKKSSTRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRK 64
Query: 112 SEGAAS-KKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKS 167
A+S + RS +++G + + GS ++ +SRS + S +SSS S
Sbjct: 65 RRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSS 121
Score = 33.5 bits (75), Expect = 1.5
Identities = 44/169 (26%), Positives = 61/169 (36%), Gaps = 26/169 (15%)
Query: 1020 GVDKKAEMGLKEREAALKEEWKQKPSIPPTLTKAPSLTDLVKSGPGKAKEPGADPAKSVI 1079
GV KK+ +G+KE +K S T+APS T K+K+ D +
Sbjct: 5 GVKKKSLLGVKENN--------KKSS-----TRAPSPTKRKDRSDEKSKDRSKDKGATKE 51
Query: 1080 IPKLD---DSSKLPGQAPEGLKVKLSDASHLSKEASEAKTGAECGRQAEMDPILWYRQEA 1136
+ D D ++ A G S +S S S TG+ G + A
Sbjct: 52 SSEKDRGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSS---------SA 102
Query: 1137 EPRMWTYVYPAKYSDIKSEDERWKEERDRKLKEERSRSKDSVPKEDGKE 1185
R + ++ S S R R RSRSK PK D KE
Sbjct: 103 SSRSGSSS-TSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKE 150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.125 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64,771,188
Number of Sequences: 37866
Number of extensions: 3554715
Number of successful extensions: 19756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 717
Number of HSP's that attempted gapping in prelim test: 15933
Number of HSP's gapped (non-prelim): 4213
length of query: 1411
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1296
effective length of database: 13,892,928
effective search space: 18005234688
effective search space used: 18005234688
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.