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Search of human proteins with 71274144
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|71274144 AT hook, DNA binding motif, containing 1 [Homo
sapiens]
(1603 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens] 3300 0.0
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 80 2e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 76 2e-13
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 70 1e-11
gi|110349719 titin isoform N2-A [Homo sapiens] 69 3e-11
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 66 3e-10
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 66 3e-10
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 65 7e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 64 1e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 3e-09
gi|160707881 formin 2 [Homo sapiens] 62 6e-09
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 61 8e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 61 1e-08
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 60 2e-08
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 60 2e-08
gi|153792012 DNA polymerase zeta [Homo sapiens] 60 2e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 60 2e-08
gi|57864582 hornerin [Homo sapiens] 58 6e-08
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 57 1e-07
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 57 1e-07
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 57 1e-07
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 57 1e-07
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 57 1e-07
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 57 1e-07
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 57 1e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 57 1e-07
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 57 2e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 56 2e-07
gi|112421108 capicua homolog [Homo sapiens] 56 2e-07
gi|153792074 proline rich 12 [Homo sapiens] 56 2e-07
>gi|71274144 AT hook, DNA binding motif, containing 1 [Homo sapiens]
Length = 1603
Score = 3300 bits (8556), Expect = 0.0
Identities = 1603/1603 (100%), Positives = 1603/1603 (100%)
Query: 1 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN 60
MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN
Sbjct: 1 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN 60
Query: 61 PRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRP 120
PRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRP
Sbjct: 61 PRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRP 120
Query: 121 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP 180
VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP
Sbjct: 121 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP 180
Query: 181 EERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELA 240
EERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELA
Sbjct: 181 EERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELA 240
Query: 241 DADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPL 300
DADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPL
Sbjct: 241 DADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPL 300
Query: 301 QPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLA 360
QPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLA
Sbjct: 301 QPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLA 360
Query: 361 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPT 420
EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPT
Sbjct: 361 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPT 420
Query: 421 GLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAK 480
GLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAK
Sbjct: 421 GLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAK 480
Query: 481 IPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMP 540
IPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMP
Sbjct: 481 IPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMP 540
Query: 541 IILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPS 600
IILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPS
Sbjct: 541 IILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPS 600
Query: 601 YAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFLH 660
YAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFLH
Sbjct: 601 YAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPESVHQAPDTQSISHFLH 660
Query: 661 RVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDFFEGIGKKKKVVAVAAAGVGGPGLTEL 720
RVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDFFEGIGKKKKVVAVAAAGVGGPGLTEL
Sbjct: 661 RVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDFFEGIGKKKKVVAVAAAGVGGPGLTEL 720
Query: 721 GHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHH 780
GHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHH
Sbjct: 721 GHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHH 780
Query: 781 GHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYF 840
GHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYF
Sbjct: 781 GHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYF 840
Query: 841 RSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAV 900
RSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAV
Sbjct: 841 RSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAV 900
Query: 901 GSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTT 960
GSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTT
Sbjct: 901 GSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTT 960
Query: 961 HPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGY 1020
HPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGY
Sbjct: 961 HPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGY 1020
Query: 1021 APPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATS 1080
APPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATS
Sbjct: 1021 APPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATS 1080
Query: 1081 AASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPN 1140
AASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPN
Sbjct: 1081 AASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPN 1140
Query: 1141 VILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSS 1200
VILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSS
Sbjct: 1141 VILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSS 1200
Query: 1201 LEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGY 1260
LEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGY
Sbjct: 1201 LEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGY 1260
Query: 1261 PSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGD 1320
PSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGD
Sbjct: 1261 PSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGD 1320
Query: 1321 SSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHF 1380
SSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHF
Sbjct: 1321 SSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHF 1380
Query: 1381 PPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAA 1440
PPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAA
Sbjct: 1381 PPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAA 1440
Query: 1441 QAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACL 1500
QAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACL
Sbjct: 1441 QAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACL 1500
Query: 1501 SAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQ 1560
SAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQ
Sbjct: 1501 SAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQ 1560
Query: 1561 DTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL 1603
DTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL
Sbjct: 1561 DTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL 1603
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 80.1 bits (196), Expect = 2e-14
Identities = 149/543 (27%), Positives = 187/543 (34%), Gaps = 140/543 (25%)
Query: 22 LREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGD 81
L E P P P L T P + PP+ + + F E+P PP + T PP ++
Sbjct: 515 LEESPLSPPEESPPSPALET-PLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS 573
Query: 82 DP----------------LPPRAAR---------------------PVSQARCPTPVGDG 104
P PP A+R P +R P D
Sbjct: 574 PPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS 633
Query: 105 SSSRRCWDN--------GRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPP 156
S ++ R++ PVV + + + LS + S RLS PP
Sbjct: 634 PMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693
Query: 157 -----APPPGDLQYSFFSSPSLANSIRS-----------PEE-----RATPHAKSERPSH 195
+PPP D +SP +S+ S PEE R+ S RP
Sbjct: 694 EDSPTSPPPEDSP----ASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE 749
Query: 196 PLYEPEP-EPRDSPQPGQGHSPGATAAATGLPPEPE-------PDSTDYSELADADILSE 247
P P P EP SPQ + H L P+PE P+ S A+ LS
Sbjct: 750 PHLSPRPEEPHLSPQAEEPH----------LSPQPEEPCLCAVPEEPHLSPQAEGPHLSP 799
Query: 248 LASLTCPEAQLLEAQALEPP-SPEPEPQLLDPQPR--FLDPQALEP----------LGEA 294
PE L Q EP SP PE L PQP L PQ+ EP L
Sbjct: 800 Q-----PEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Query: 295 LELPPLQPLAD-PLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQP 353
LE PPL P + P PG P E L P L LL P + P
Sbjct: 855 LEKPPLSPRPEKPPEEPG-------QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907
Query: 354 LGHCPLAEPLRLDLCSPHG---------PPGPEGHPKYALRRTDRPKIL--CRRRKAGRG 402
L PL E L L SP G PP P P + P L + G
Sbjct: 908 LS--PLPEELPL---SPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962
Query: 403 RKADAGPEGRL----LPLPMPTGLVAALAEPPPPPP---PPPPALP-GP-GPVSVPELKP 453
K D+ PE L L P+ A +P P PP PP P P GP P+ + L P
Sbjct: 963 AKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPP 1022
Query: 454 ESS 456
+ S
Sbjct: 1023 QCS 1025
Score = 59.7 bits (143), Expect = 2e-08
Identities = 132/504 (26%), Positives = 173/504 (34%), Gaps = 103/504 (20%)
Query: 32 PPTPRPLLPT---RPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLP--P 86
PP PL P P + PP+ + + ++P PP D PP + PL P
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724
Query: 87 RAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGV--- 143
P CP G S R + ++ RP + + LS + +
Sbjct: 725 LLPLPEEPQLCPRSEGPHLSPRP--EEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782
Query: 144 ----HLD--CGGLRLSRPPAPPPGDLQYSFFS-----SPSLANSIRSP---EERATPHAK 189
HL G LS P P +L S + SP SP E +P ++
Sbjct: 783 PEEPHLSPQAEGPHLS----PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
Query: 190 ----SERPSHPLYEPEPE-PRDSPQPGQG-HSPGATAAATGLPPEPEPDSTDYSELADAD 243
S RP PE E P SP+P + PG A LP P P S L
Sbjct: 839 EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP 898
Query: 244 ILSELASLTCPEAQLLEAQALEPPS-PEPEPQLLDPQP---------RFLDPQALEPLGE 293
LSE P + L E L P P PQL+ P P P AL PLGE
Sbjct: 899 ALSEPGEP--PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE 956
Query: 294 ALELP--------PLQPLADPLGLPGLALQALDT-LPDSLESQLLDPQALDPLPKLLDVP 344
LE P P PLA P+ L+T + E+ DP+ + P+ L P
Sbjct: 957 -LEYPFGAKGDSDPESPLAAPI---------LETPISPPPEANCTDPEPVPPM-ILPPSP 1005
Query: 345 GRRLEPQQPLGHCPLAEPLRLDLCSP---------HGPPGPEGHPKYALR---------- 385
G + P P+ L EPL CSP + PP P L
Sbjct: 1006 GSPVGPASPI----LMEPLP-PQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGK 1060
Query: 386 ---RTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPG 442
+D ++ + + A PLP P G L+ P P P P G
Sbjct: 1061 VVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMG---DLSCPAPSPAPALDDFSG 1117
Query: 443 PGP-------VSVPELKPESSQTP 459
G + P +PE QTP
Sbjct: 1118 LGEDTAPLDGIDAPGSQPEPGQTP 1141
Score = 53.9 bits (128), Expect = 1e-06
Identities = 78/276 (28%), Positives = 93/276 (33%), Gaps = 38/276 (13%)
Query: 202 PEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEA 261
P P +SP SP + T PPE S EL A L E L+ P LE
Sbjct: 442 PPPEESPL-----SPPPEESPTSPPPEASRLSPPPEELP-ASPLPEALHLSRP----LEE 491
Query: 262 QALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLP 321
L PP PE P P+ P PL E PP L PL P +A P
Sbjct: 492 SPLSPP-PEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPP---EASPLSP 547
Query: 322 DSLESQLLDPQALDPLPKLLDVPGRRLEP-------QQPLGHCPLAEPLRLDLC------ 368
ES L P + LP RL P P P++ P
Sbjct: 548 PFEESPLSPPP--EELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEE 605
Query: 369 SPHGPP---GPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAA 425
SP PP P P A R + P+ + RL PLP +V+
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP----VVSR 661
Query: 426 LAEPPPPPP--PPPPALPGPGPVSVPELKPESSQTP 459
L+ PP P PPP P P L P +P
Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSP 697
Score = 52.8 bits (125), Expect = 3e-06
Identities = 82/313 (26%), Positives = 98/313 (31%), Gaps = 35/313 (11%)
Query: 176 SIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTD 235
+IRS E+ TP P P P EP QG G + P EP P +
Sbjct: 357 TIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQ-PKEPGPLQCE 415
Query: 236 YSELADADILSELASLTCP---EAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLG 292
L A + E L P E LL P SP PE P P + L P
Sbjct: 416 AKPLGKAGVQLE-PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPP---EASRLSPPP 471
Query: 293 EALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLE--P 350
E L P PL + L L L+ P ES L P P L + P E P
Sbjct: 472 EEL---PASPLPEALHL-SRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESP 527
Query: 351 QQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPE 410
P PL+ P SP P P L + P+ + E
Sbjct: 528 PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
Query: 411 GRLLPLPMPTGLVAALAEPPPPPPP---------------------PPPALPGPGPVSVP 449
+ P P + L E P PPP P P P+S P
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647
Query: 450 ELKPESSQTPVVS 462
S PVVS
Sbjct: 648 PEVSRLSPLPVVS 660
Score = 50.8 bits (120), Expect = 1e-05
Identities = 122/479 (25%), Positives = 151/479 (31%), Gaps = 108/479 (22%)
Query: 18 SPDYLREPKYYPGGPPTPRPL-LPTRPPASPPDKAFSTHA-------FSENPRPPPRRDP 69
+P Y EP++ P PPT P PT PA PP S+ F P PR P
Sbjct: 2180 APAYPLEPRF-PTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQP 2238
Query: 70 STRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMK 129
ST P K P A P S VG G +S P++ +
Sbjct: 2239 ST--PDPFLKPRCPSLDNLAVPESPG-----VGGGKASE-----------PLLSPPPFGE 2280
Query: 130 DLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAK 189
L + G S P PP F SPS + E + K
Sbjct: 2281 SRKALEVKKEELGA---------SSPSYGPPN---LGFVDSPSSGTHLGGLELKTPDVFK 2328
Query: 190 SERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELA 249
+ PL P + PG G P A L P P P D +
Sbjct: 2329 A-----PL-TPRASQVEPQSPGLGLRPQEPPPAQALAPSP-PSHPD---------IFRPG 2372
Query: 250 SLTCPEAQLLEAQALEPPSPEP----EPQLLDPQPRFLDPQALEPLGEALELPPL--QPL 303
S T P AQ +PP PE P+ L P P + P ++ PL +PL
Sbjct: 2373 SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS--PQSQSSSQSPLTPRPL 2430
Query: 304 ADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQP--------LG 355
+ P + PD PQ+ DP L P PQ P L
Sbjct: 2431 SAEAFCPSPVTPRFQS-PDPYSRPPSRPQSRDPFAPLHKPP----RPQPPEVAFKAGSLA 2485
Query: 356 HCPLAE---PLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGR 412
H L P L P GP G + P + R G G
Sbjct: 2486 HTSLGAGGFPAAL-------PAGPAGELHAKVPSGQPPNFV---RSPGTGAFVGT----- 2530
Query: 413 LLPLPMPTGLVAALAEPPPPPPPPPPALP---------GPGPVSVPELKPESSQTPVVS 462
P PM A+ EP PP P P LP GPGP KP+S+ V +
Sbjct: 2531 --PSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG---KPQSTNYTVAT 2584
Score = 50.1 bits (118), Expect = 2e-05
Identities = 129/527 (24%), Positives = 165/527 (31%), Gaps = 156/527 (29%)
Query: 32 PPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAARP 91
P PL P PP+ E+P PP + T PP ++ P A P
Sbjct: 428 PQLEAPLNEEMPLLPPPE---------ESPLSPPPEESPTSPPPEASRLSPPPEELPASP 478
Query: 92 VSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLR 151
+ +A LS+ L+ S
Sbjct: 479 LPEA------------------------------------LHLSRPLEESP--------- 493
Query: 152 LSRPP-----APPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERP------SHPLYEP 200
LS PP +PPP +S L S SP E + P E P + PL P
Sbjct: 494 LSPPPEESPLSPPPESSPFS-----PLEESPLSPPEESPPSPALETPLSPPPEASPLSPP 548
Query: 201 EPEPRDSPQPGQ-GHSPGATAAATGLPPE-----PEPDSTDYSELADADIL----SELAS 250
E SP P + SP A+ PPE P P+ + S +A L E
Sbjct: 549 FEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPL 608
Query: 251 LTCPEAQLL----EAQALEPP---------------SPEPEPQLLDPQP---RFLDPQAL 288
PE L EA L PP SP PE L P P R P
Sbjct: 609 SPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668
Query: 289 EPLGEALELPPLQPLAD-----------PLGLPGLALQALDTLPDSLESQLLDPQALDPL 337
PL E P P + P P A DSL S L+ L PL
Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728
Query: 338 PKLLDV----PGRRLEPQQPLGH----------CPLAEPLRLD-------LCS----PHG 372
P+ + G L P+ H P AE L LC+ PH
Sbjct: 729 PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788
Query: 373 PPGPEG-------HPKYALRRTDRPKIL------CRRRKAGRGRKADAGPEGRLLPLPMP 419
P EG + +T+ P + C + + E L P P
Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848
Query: 420 TGLVAALAEPP-PPPPPPPPALPG--PGPVSVPELKP--ESSQTPVV 461
+ L L +PP P P PP PG P P +P P E S +P++
Sbjct: 849 SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895
Score = 38.1 bits (87), Expect = 0.069
Identities = 104/399 (26%), Positives = 143/399 (35%), Gaps = 52/399 (13%)
Query: 79 KGDDPLPPRA---ARPV-SQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRL 134
K D P P A PV S P G+G S D R++ + ++ KDL +L
Sbjct: 1840 KADTPGPEDGGVKASPVPSDPEKPGTPGEGMLSS---DLDRISTEELPKMES--KDLQQL 1894
Query: 135 SQDLQHSG--VHLDCG--GLRLSRPPAPPP---GDLQYSFFSSPSLANSIRSPEERATPH 187
+D+ S HL CG GL SR P P G L S S +S P +P
Sbjct: 1895 FKDVLGSEREQHLGCGTPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSY--PGLCQSPF 1952
Query: 188 AKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLP-PEPEPDSTDYSE--LADADI 244
S R + PEP DSP G G G T + P E E D Y++ L +
Sbjct: 1953 LDS-RERGGFFSPEPGEPDSPWTGSG---GTTPSTPTTPTTEGEGDGLSYNQRSLQRWEK 2008
Query: 245 LSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLA 304
EL L+ + +L A P + P + + P + + P LQ
Sbjct: 2009 DEELGQLS-TISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAAD--KAPYLQKAK 2065
Query: 305 DPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLE-PQQP--LGHCPLAE 361
D A ++ + ESQ+ + + + D P L P QP LG P A
Sbjct: 2066 D-----NRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAA 2120
Query: 362 PLRLDLCSPHGPPG----PEGH---PKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLL 414
+ + SP P G +G P ++ D P L + + +
Sbjct: 2121 APTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQ---------V 2171
Query: 415 PLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKP 453
P P GL A P P PP P P P P P
Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP 2210
Score = 37.4 bits (85), Expect = 0.12
Identities = 75/306 (24%), Positives = 105/306 (34%), Gaps = 67/306 (21%)
Query: 1297 PKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSD 1356
P+ P++P ++SP SP P SR E P S P D
Sbjct: 666 PEESPLSPPPEESPT------------SPPPEASRLSPPPEDSPTSPPPEDSPASPPPED 713
Query: 1357 GTFGQGFHCDSPSLGAPE-------LDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFK 1409
+SP L PE +G H P P + + SP +
Sbjct: 714 SLMSLPLE-ESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE-----E 767
Query: 1410 EELRPPPTKLAACE-PLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWY 1468
L P P + C P + L + G HLS P + + SP +
Sbjct: 768 PHLSPQPEEPCLCAVPEEPHLSPQAEG------PHLS----PQPEELHLSPQTEEPHLSP 817
Query: 1469 PPGSAARSP-PYEGKVGTGLLADFLGRTEAACLS--------APHLASPPATPKADKEPL 1519
P SP P E + ++E CLS +P L PP +P+ +K P
Sbjct: 818 VPEEPCLSPQPEESHLSP--------QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPE 869
Query: 1520 EMARPPG-------PPRGPAAAAAGYGCPLLS---DLTLSPVPRDSLLPLQDTAYRYPGF 1569
E + P PP G + + G P LS + LSP+P + LPL + P
Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEE--LPLSPSG--EPSL 925
Query: 1570 MPQAHP 1575
PQ P
Sbjct: 926 SPQLMP 931
Score = 37.4 bits (85), Expect = 0.12
Identities = 80/376 (21%), Positives = 121/376 (32%), Gaps = 58/376 (15%)
Query: 1 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN 60
+ + PQ S V P +P+ P + P L RP S S
Sbjct: 804 LHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPR 863
Query: 61 PRPPPRRDPSTRRPPVL----AKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRV 116
P PP P L G+ L P P P+ +G
Sbjct: 864 PEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP 923
Query: 117 NLRPVVQLID-IMKDLTRLSQDLQHSGVHLDCGGLRLSRPPA-PPPGDLQYSFFS----- 169
+L P + D + L+ + + + PPA P G+L+Y F +
Sbjct: 924 SLSPQLMPPDPLPPPLSPI---------------ITAAAPPALSPLGELEYPFGAKGDSD 968
Query: 170 --SPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPP 227
SP A + +P P A P EP P P PG P + LPP
Sbjct: 969 PESPLAAPILETPIS-PPPEANCTDP-----EPVPPMILPPSPGSPVGPASPILMEPLPP 1022
Query: 228 EPE--------PDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQ 279
+ P ++ S+ + + + S P +++ ++ +P+
Sbjct: 1023 QCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPE 1082
Query: 280 PRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPK 339
L+P A PL P+ L+ P P AL L + D LD
Sbjct: 1083 CPALEPSATSPLPS-----PMGDLSCPAPSPAPALDDFSGLGE-------DTAPLDG--- 1127
Query: 340 LLDVPGRRLEPQQPLG 355
+D PG + EP Q G
Sbjct: 1128 -IDAPGSQPEPGQTPG 1142
Score = 37.0 bits (84), Expect = 0.15
Identities = 22/68 (32%), Positives = 26/68 (38%)
Query: 35 PRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQ 94
PRP P R PA P + +P PPP +RP L LP A P +
Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340
Query: 95 ARCPTPVG 102
P P G
Sbjct: 4341 PGTPKPQG 4348
Score = 36.2 bits (82), Expect = 0.26
Identities = 79/320 (24%), Positives = 101/320 (31%), Gaps = 49/320 (15%)
Query: 179 SPEERATPHAKSERPSHPLY-EPEPEPRDSPQPGQGHSPGATAAATGLPPE--PEPDSTD 235
+P P + P++P Y P P P G PGA G P E P T
Sbjct: 2180 APAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGA-----GQPGEFHTTPPGTP 2234
Query: 236 YSELADADILSELASLTCPEAQLLEAQALEPPSP-----EPEPQLLDPQPRFLDPQALEP 290
+ + D CP L P SP + LL P P +ALE
Sbjct: 2235 RHQPSTPD---PFLKPRCPSLDNLAV----PESPGVGGGKASEPLLSPPPFGESRKALEV 2287
Query: 291 LGEALELPPLQPLADPLGL-------PGLALQALDTLPDSLESQLLDPQALDPLPKLLDV 343
E EL P P L G L L+ + L P+A P+
Sbjct: 2288 KKE--ELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQS--- 2342
Query: 344 PGRRLEPQQPLGHCPLAE--PLRLDLCSPHGPPGPEGHPKYALRRTDRPKILC-----RR 396
PG L PQ+P LA P D+ P P P R P C R
Sbjct: 2343 PGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS 2402
Query: 397 RKAGRGRKADAGPEGR------LLPLPMPTGLVAALAEPP----PPPPPPPPALPGPGPV 446
+ + A P+ + L P P+ P P P PP+ P
Sbjct: 2403 LPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDP 2462
Query: 447 SVPELKPESSQTPVVSTRKG 466
P KP Q P V+ + G
Sbjct: 2463 FAPLHKPPRPQPPEVAFKAG 2482
Score = 36.2 bits (82), Expect = 0.26
Identities = 56/213 (26%), Positives = 78/213 (36%), Gaps = 32/213 (15%)
Query: 196 PLYEPEPEPRDSPQPGQGHSPGATAAATGLPP-EPEPDSTDYSELADADILSELASLTCP 254
PL E PR P PGA + L P P P + E L +S
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPT 4332
Query: 255 EAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLAL 314
EAQL P +P+P+ L+P P + P A + LAD L GL
Sbjct: 4333 EAQL---PPTHPGTPKPQGPTLEPPPGRVSPAAAQ-------------LADTLFSKGLGP 4376
Query: 315 QALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEP---QQPLGHCPLAEPLRLDLCS-- 369
PD+L ++ P+ +P LD ++ P Q + P EP L S
Sbjct: 4377 W---DPPDNL-AETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVK 4432
Query: 370 ------PHGPPGPEGHPKYALRRTDRPKILCRR 396
P G PG H A R++ +L ++
Sbjct: 4433 REANGEPIGAPGTSNHLLLAGPRSEAGHLLLQK 4465
Score = 35.8 bits (81), Expect = 0.34
Identities = 40/129 (31%), Positives = 48/129 (37%), Gaps = 21/129 (16%)
Query: 1475 RSPPY-EGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMA-RPPGPPRGPA 1532
++PPY E T L LG P L P + L RP GPPR PA
Sbjct: 4239 QTPPYQEPGTQTSPLQGLLG-------CQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPA 4291
Query: 1533 AAAAGYGCPLLSDLTLSPVP-------RDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGF 1585
A P+L + +P P R S LP + +P HPG PK
Sbjct: 4292 PPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGT---PKP-- 4346
Query: 1586 LGPMAEPHP 1594
GP EP P
Sbjct: 4347 QGPTLEPPP 4355
Score = 34.3 bits (77), Expect = 1.00
Identities = 33/131 (25%), Positives = 47/131 (35%), Gaps = 18/131 (13%)
Query: 194 SHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTC 253
S+ + PE R +P +G + G GL + D+ + DA +
Sbjct: 4814 SYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQL 4873
Query: 254 PEAQLL--EAQALEPPSPE----------------PEPQLLDPQPRFLDPQALEPLGEAL 295
LL E+ A EPP+ P P+ P P L P P E L
Sbjct: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPL 4933
Query: 296 ELPPLQPLADP 306
P +PLA+P
Sbjct: 4934 VELPTEPLAEP 4944
Score = 33.9 bits (76), Expect = 1.3
Identities = 70/291 (24%), Positives = 97/291 (33%), Gaps = 57/291 (19%)
Query: 197 LYEPEPEPRDSPQ--------PGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSEL 248
L +P+P+P+ S PGQ + G + S SE + L
Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQ 4136
Query: 249 ASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLG 308
S++ + Q L P +P L P PQ +P G L+ G
Sbjct: 4137 PSVSLGDQPGSMTQNLLGPQ---QPMLERPMQNNTGPQPPKP-GPVLQ--------SGQG 4184
Query: 309 LPGLAL---------QALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCP- 358
LPG+ + Q L + + + L PQ L LL R+L+ Q + P
Sbjct: 4185 LPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALL--MQRQLQQSQAVRQTPP 4242
Query: 359 ------LAEPLRLDL-CSPH--GPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGP 409
PL+ L C P G PGP+ P L G G + P
Sbjct: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQEL---------------GAGPRPQGPP 4287
Query: 410 EGRLLPLPMPTGLVAALAEPPPPP-PPPPPALPGPGPVSVPELKPESSQTP 459
P + TG V P PPP P P P P +L E+ P
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPP 4338
Score = 33.1 bits (74), Expect = 2.2
Identities = 23/70 (32%), Positives = 29/70 (41%), Gaps = 8/70 (11%)
Query: 25 PKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPP---RRDPSTRRPPVLAK-- 79
P P PP+P P PP P + T +E P P P P + RP A+
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVE-LPTEPLAEPPVPSPLPLASSPESARPKPRARPP 4968
Query: 80 --GDDPLPPR 87
G+D PPR
Sbjct: 4969 EEGEDSRPPR 4978
Score = 32.3 bits (72), Expect = 3.8
Identities = 25/57 (43%), Positives = 27/57 (47%), Gaps = 6/57 (10%)
Query: 29 PGGPPT-PRPLLPTRPPASPPDKAFSTHAFS-ENPRPPPRRDP----STRRPPVLAK 79
P PPT P LPT P A PP + A S E+ RP PR P RPP L K
Sbjct: 4925 PASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKK 4981
Score = 31.6 bits (70), Expect = 6.5
Identities = 36/135 (26%), Positives = 47/135 (34%), Gaps = 43/135 (31%)
Query: 947 LVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGN 1006
L+PPP SP + PP + PT P + S
Sbjct: 440 LLPPPE---ESPLSPPPEES----------------PTSP--------PPEASRLSPPPE 472
Query: 1007 SLPASP--------SSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPF--------SGSA 1050
LPASP + +PPP P PP ++S FS E +P S +
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPAL 532
Query: 1051 PTPLRCDSRASTVSP 1065
TPL AS +SP
Sbjct: 533 ETPLSPPPEASPLSP 547
Score = 31.6 bits (70), Expect = 6.5
Identities = 13/27 (48%), Positives = 15/27 (55%)
Query: 423 VAALAEPPPPPPPPPPALPGPGPVSVP 449
V L+ PPP P PPP+ P P S P
Sbjct: 4903 VRQLSAPPPEEPSPPPSPLAPSPASPP 4929
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 76.3 bits (186), Expect = 2e-13
Identities = 119/467 (25%), Positives = 155/467 (33%), Gaps = 67/467 (14%)
Query: 25 PKYYPGGPP--TPRPLLPTRPPASPPDKAF-STHAFSENPRPPPRRDPSTRRPPVLAKGD 81
P P PP TP PL P P A P + S A + PP P + PP L
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
Query: 82 DPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHS 141
P + S P+P+ SS + G L+ + + T+ S
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLAL-SSLQATTSLGSPTLQATHSFLTMSPRQTQAS------ 440
Query: 142 GVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIR---SPEE--------RATPHAKS 190
L S PP PP S +SP L S+ SP +A S
Sbjct: 441 ---LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497
Query: 191 ERPSHPLYE---PEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSE 247
P PL P E + S P +P A+ L P +
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPH 557
Query: 248 LASLTCPEAQLLEA--QALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLAD 305
L + CP L+A L P PE + P P+ A PL + L PPL PLA
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL-QGLPSPPLSPLAT 616
Query: 306 P--LGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQP------LGHC 357
P P LAL L P S L P A PQ P L
Sbjct: 617 PPPQAPPXLALPPLQAPPSPPASPPLSPLATP-------------SPQAPNALAVHLLQA 663
Query: 358 PLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLP 417
P + P + +P PP A + P L A P ++ P P
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL-------------AAPPLQVPPSP 710
Query: 418 MPTGLVAALAEPPPPPPPP---PPALPGPGPVSVPELKPESSQTPVV 461
+ ++ A PPP PPP PP P P + P + P ++ P V
Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Score = 68.9 bits (167), Expect = 4e-11
Identities = 124/485 (25%), Positives = 155/485 (31%), Gaps = 102/485 (21%)
Query: 16 CSSPDYLREPKYYPGGPPTPRPLLPTRPP-------ASPPDKAFSTHAFSENPRPPPRRD 68
C +P L+ P PP P PP ASPP + + S PPP+
Sbjct: 563 CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP 622
Query: 69 PSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIM 128
P PP+ A P P A+ P+S P+P + +
Sbjct: 623 PXLALPPLQA----PPSPPASPPLSPLATPSPQAPNALA--------------------- 657
Query: 129 KDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHA 188
VHL L P +PPP + FS P A+ SP A
Sbjct: 658 --------------VHL------LQAPFSPPPSPPVQAPFSPP--ASPPVSPSATPPSQA 695
Query: 189 KSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSEL 248
+ PL P P P SP AT PP P + +S
Sbjct: 696 PPSLAAPPLQVPPSPPASPPM-----SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 249 ASLTCPEAQLLEAQALE-PPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPL-ADP 306
A+ LL A L+ PPSP P L P P P AL PPLQ L + P
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSP---PASLPMSPLAKPPPQAPP---ALATPPLQALPSPP 804
Query: 307 LGLPG---------LALQALDTLPDS----LESQLLDPQALDPLPKLLDVPGRRLEPQQP 353
PG L + L T P L + LL P L P R P P
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---PPTP 861
Query: 354 LGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRG-RKADAGPEGR 412
++ P +P PP P P L D R D+GPEG
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921
Query: 413 LLPLPMPTGLVAAL-----AEPPPPP---------PPPPPALPGPGPV----SVPELKPE 454
P P +AA + P PP P P P GPG ++ E +
Sbjct: 922 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 981
Query: 455 SSQTP 459
S TP
Sbjct: 982 ESATP 986
Score = 67.4 bits (163), Expect = 1e-10
Identities = 123/471 (26%), Positives = 151/471 (32%), Gaps = 81/471 (17%)
Query: 31 GPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAAR 90
G P P P RPP P K+ S+ + P P+ RR P G L A+R
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP----SPAARRRPSAGGG---LQRPASR 240
Query: 91 PVSQARCP--TPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCG 148
+S + P +P G S+R R P SQ
Sbjct: 241 SLSSSATPLSSPARSGPSAR---GTPRAPAHP--------------SQPKPK-------- 275
Query: 149 GLRLSRPP---------APPPGDLQYSFFSSPS----LANSIRSPEERATPHAKSERPSH 195
GL+ RPP AP G L S ++PS A + P+ ATP + PS
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335
Query: 196 PLYEP----EPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASL 251
PL P P P P SP AT + P P L + SL
Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395
Query: 252 TCPEAQ----------LLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQ 301
T P Q L +L P+ + L PR P A P
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455
Query: 302 PLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHC---P 358
PL PL LP A L T S L P + PL L + PQ PL P
Sbjct: 456 PLQAPLSLP--ASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASH--SPQAPLSSLIMPP 511
Query: 359 LAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPM 418
L L S PP P + P L + P PL
Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571
Query: 419 PTGLVAALAEPPP--------PPPPPPPALPGPGPVSVPE--LKPESSQTP 459
P + L PPP PPP PPAL P +P L P ++ P
Sbjct: 572 PP---SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Score = 52.0 bits (123), Expect = 5e-06
Identities = 106/433 (24%), Positives = 145/433 (33%), Gaps = 76/433 (17%)
Query: 702 KKVVAVAAAGVGGPGLTELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGF 761
+K +A A G+GG + P R G R SR + E+ P
Sbjct: 55 RKPLAERAGGIGGATI-----PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT 109
Query: 762 GEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGA 821
G G P P GQ G + T AR A+ + A G+ T
Sbjct: 110 SPGPVSSPGRASGTTRPG---PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166
Query: 822 PS-GQTELSQERQNLFTGYFRSLLDSDDS--------------SDLLDFALSASRPESRK 866
P+ G + R++ G L S S + + + P +R+
Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
Query: 867 ASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQP------VLSARQT 920
G A + AT S A++ P A G+ A A PS QP L Q
Sbjct: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQV 285
Query: 921 FPPGRAASYGLTPAASDCRAAE----TFPKLVPPP-SAMARSPTTHPPAN---TYLPQYG 972
PP + A+ L P +S A T + VPPP +A P T PP+ T LP
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP--- 342
Query: 973 GYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGP---- 1028
AP P S PA+P S PP P
Sbjct: 343 --------LAPPSPSAPPSLQTLP----------SPPATPPSQAPPSMTTPPMQAPPSLQ 384
Query: 1029 CLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGG----------YMVPKGTTASA 1078
+PP + +S P + P+PL S +T S G M P+ T AS
Sbjct: 385 TIPPIQVPHSLTS---PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
Query: 1079 TSAASAASSSSSS 1091
TS + AS+ S
Sbjct: 442 TSPSRPASTPPDS 454
Score = 50.1 bits (118), Expect = 2e-05
Identities = 162/756 (21%), Positives = 231/756 (30%), Gaps = 89/756 (11%)
Query: 867 ASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRA 926
A+G P + G AT P +A P + + S P + PP +
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN 108
Query: 927 ASYGLTPAASDCRAAETFPK--------LVPPPSAMARSPTTHPPANTYLPQYGGYGAGQ 978
S G P +S RA+ T + +AR T P + L GA +
Sbjct: 109 TSPG--PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA----GARR 162
Query: 979 SVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFF 1038
PT A S A G+ LP SA PPT GP S AS
Sbjct: 163 DTSGPTPGTPSPAMARR---SRAAGTEVGLPRPAPSARPR----PPTEGPRKSVSSASEH 215
Query: 1039 SSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTA-SATSAASAASSSSSSFQPSPE 1097
S++E +P + P+ R ++ S P + A S SA + + QP P+
Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275
Query: 1098 NCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQT 1157
+ P R+ A+ A P ++ P+ + P T
Sbjct: 276 GLQALRPPQVTPPRKD------AAPAL----GPLSSSPLATPSPSGTKARPVPPPDNAAT 325
Query: 1158 AVSETFSESSSDSTQF----NQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASS 1213
+ T S +T P + S ++ Q+ S M +
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385
Query: 1214 APGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPSKRST------G 1267
P S+ S P S L + + + G P+ ++T
Sbjct: 386 IPPIQVPHSLTSPSLQAP------------PSPLALSSLQATTSLGSPTLQATHSFLTMS 433
Query: 1268 PRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLP 1327
PRQ + + A +A P P +P Q S + S ++ PL
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQA---PLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 1328 SQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPP 1387
+ S + P + M P SL P L+ + P LA PP
Sbjct: 491 ALS---SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE--NLPSLAPPP 545
Query: 1388 TVFDAGLQKAYSPTCSPTLGFKE-----ELRPPPTKLAACEPLKHGLQGASLGHAAAAQA 1442
LQ A +P +P L L+ PP+ L P A A A
Sbjct: 546 ------LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 1443 HLSCRDL------PLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTE 1496
+ L PL P +P P S SPP A
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP--NALA 657
Query: 1497 AACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSL 1556
L AP SPP +P + P PP P+A P L+ L P
Sbjct: 658 VHLLQAPF--SPPPSPPVQ---APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712
Query: 1557 LPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEP 1592
P + P PQA P L P P A P
Sbjct: 713 SPPMSPSATPP---PQAPPPLAAPPLQVPPSPPASP 745
Score = 48.5 bits (114), Expect = 5e-05
Identities = 69/270 (25%), Positives = 93/270 (34%), Gaps = 42/270 (15%)
Query: 25 PKYYPGGPPTPR-PLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLA----- 78
P P P PR P L PP P ++ S +PPP+ P+ PP+ A
Sbjct: 745 PPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
Query: 79 ---KGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQL---------ID 126
G P P A+ P+S P P V P++Q+ +
Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPP-----------VLAAPLLQVPPSPPASPTLQ 853
Query: 127 IMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLA----NSIRSPEE 182
+ D SG L L L+ P PPP S S P LA ++ +PEE
Sbjct: 854 APRRPPTPGPDTSVSGPRLT---LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 910
Query: 183 RATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLP--PEPEPDSTDYSELA 240
+ E + P+ E P A G P P P P +T
Sbjct: 911 LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG---PG 967
Query: 241 DADILSELASLTCPEAQLLEAQALEP-PSP 269
AD L + PE+ AL+P PSP
Sbjct: 968 SADGLCTIYETEGPESATPAPGALDPGPSP 997
Score = 44.7 bits (104), Expect = 7e-04
Identities = 86/349 (24%), Positives = 110/349 (31%), Gaps = 40/349 (11%)
Query: 1253 ASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDL 1312
A S S R+ R P GRG A AK G + PL Q +
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 1313 GLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGA 1372
+ + P +S A G R D GP P TPS + +G
Sbjct: 137 SAEETVARGKATEAPKRS-ALSAGARR--DTSGP---TPGTPSPA-MARRSRAAGTEVGL 189
Query: 1373 PELDGKHFPPLAHPPTVFDAGLQKAYSPTC--SPTLGFKEELRPPPTKLAACEPLKHGLQ 1430
P P PPT G +K+ S S T R P P L
Sbjct: 190 PRPAPSARP---RPPT---EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 1431 GASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLAD 1490
++ ++ A++ S R P H P KG PP +PP
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV---TPP------------ 288
Query: 1491 FLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSP 1550
R +AA P +SP ATP PP P A PL + L L+P
Sbjct: 289 ---RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAP 345
Query: 1551 VPRDSLLPLQDTAYRYPGFMP-QAHPGLGGGPKSG-----FLGPMAEPH 1593
P S P T P P QA P + P + P+ PH
Sbjct: 346 -PSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH 393
Score = 43.5 bits (101), Expect = 0.002
Identities = 73/309 (23%), Positives = 93/309 (30%), Gaps = 57/309 (18%)
Query: 1297 PKPQPVNPLFQDSPD----LGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPS 1352
P P++PL SP L + S P P F P + P + PS
Sbjct: 637 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP---VSPSATPPS 693
Query: 1353 TPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEEL 1412
+P + PP PP + LQ SP SP +
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753
Query: 1413 RPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGS 1472
P L A PL+ + + A +S PL +P +P T PP
Sbjct: 754 PPRVPPLLAAPPLQ-------VPPSPPASLPMS----PLAKPPPQAPPALAT----PPLQ 798
Query: 1473 AARSPPYEGKVGTGLLADFLGRT----EAACLSAPHLASPPATPKADKEPLEMARPPGPP 1528
A SPP A F G+ A+ +P PP P PL + PP PP
Sbjct: 799 ALPSPP----------ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPP 847
Query: 1529 RGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYP----GFMPQAHPGLGGGPKSG 1584
P A PR P DT+ P P P P S
Sbjct: 848 ASPTLQA----------------PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 891
Query: 1585 FLGPMAEPH 1593
GP H
Sbjct: 892 LSGPDLAGH 900
Score = 41.2 bits (95), Expect = 0.008
Identities = 161/693 (23%), Positives = 224/693 (32%), Gaps = 115/693 (16%)
Query: 934 AASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGA-GQSVFAPTKPFTGQDC 992
AA+ AA L P P R P PA L G GA G+ A G
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAA--LRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 993 ANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPT 1052
A +G + A SS + A P G PP+K ++P
Sbjct: 70 IPES----APRAGPTRSAGTSSRNPASRPPASGRGERAPPAK-------------NTSPG 112
Query: 1053 PLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQFAGASQWPFRQ 1112
P+ RAS + G + KG SA + ++ + P+ AGA +
Sbjct: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA-----PKRSALSAGARRDTSGP 167
Query: 1113 GYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQ 1172
G A S+ P+ P+K ++ SE + S + +
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK--SVSSASEHSTTEPSPAAR 225
Query: 1173 FNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPG 1232
+P GGG +R S + SS + LSS + AP + + +P
Sbjct: 226 -RRPSAGGGLQRPASRSLSSSA-TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
Query: 1233 RGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQPRGGRG-------------GGA 1279
+ + D A LG P S+S A+ PS P P
Sbjct: 284 QVTPPRKDAAPA--LG-PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340
Query: 1280 CSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERD 1339
A + +P P P P Q P + S+ +P +
Sbjct: 341 LPLAPPSPSAPPSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPI--------QV 391
Query: 1340 PCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGL----Q 1395
P P P +P + Q + SLG+P L H L P A L +
Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQA----TTSLGSPTLQATH-SFLTMSPRQTQASLTSPSR 446
Query: 1396 KAYSPTCSPTLGFKEELRPPP---TKLA-ACEPLK-----HGLQGASLGHAAAAQAHLSC 1446
A +P SP L L P T L+ A PL H LQ S + + QA LS
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSS 506
Query: 1447 RDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACLSAPHLA 1506
+P P S + PP S +PP E LA +T +A L+ PHL
Sbjct: 507 LIMP---PLETQSSLAPPSLQTPPASLT-TPPLENLPS---LAPPPLQTASAPLTTPHLE 559
Query: 1507 SPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRY 1566
+PP P + PP P LT P S +
Sbjct: 560 TPPCPA-----PCPLQAPPSP------------------LTTPPPETPSSIATPP----- 591
Query: 1567 PGFMPQAHPGLGGGPKSGF----LGPMAEPHPE 1595
PQA P L P G L P+A P P+
Sbjct: 592 ----PQAPPALASPPLQGLPSPPLSPLATPPPQ 620
Score = 39.3 bits (90), Expect = 0.031
Identities = 69/238 (28%), Positives = 85/238 (35%), Gaps = 43/238 (18%)
Query: 1368 PSLGAPELDGKHFPPLAH--------PPTVFDAGLQKAYSPTCSPTLGFKEELRP-PPTK 1418
P+L +P L G PPL+ PP + LQ SP SP L P P
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655
Query: 1419 LAACEPLKHGLQGA-SLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSP 1477
LA H LQ S + QA S P P PS + PP SP
Sbjct: 656 LAV-----HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710
Query: 1478 PYEGKVGTGLLADFLGRTEAACLSAPHLASPP-ATPKADKEPLEM--ARPPGPPRGPAAA 1534
P A+ +P PP A P PL++ + P PP P+A
Sbjct: 711 P------------------ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752
Query: 1535 AAGYGCPLLS--DLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMA 1590
PLL+ L + P P S LP+ A + P PQA P L P P A
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPAS-LPMSPLA-KPP---PQAPPALATPPLQALPSPPA 805
Score = 36.2 bits (82), Expect = 0.26
Identities = 67/251 (26%), Positives = 85/251 (33%), Gaps = 24/251 (9%)
Query: 864 SRKASGTYAGPPTSA---LPAQRGLATF--PSRGAKASPVAVG-----SSGAGADPS--- 910
SR AS PP A LPA L T P+ +SP+ + SS A P
Sbjct: 445 SRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL 504
Query: 911 ---FQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANT- 966
P L + + P S PA+ E P L PPP A +P T P T
Sbjct: 505 SSLIMPPLETQSSLAP---PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561
Query: 967 YLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTG 1026
P A S P T A + + L PS S PPP
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621
Query: 1027 GP--CLPPSKASFFSSSEGAPFSGSA-PTPLRCDSRASTVSPGGYMVPKGTTASATSAAS 1083
P LPP +A S P S A P+P ++ A + + P A +
Sbjct: 622 PPXLALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680
Query: 1084 AASSSSSSFQP 1094
A+ S S P
Sbjct: 681 ASPPVSPSATP 691
Score = 34.3 bits (77), Expect = 1.00
Identities = 72/322 (22%), Positives = 95/322 (29%), Gaps = 62/322 (19%)
Query: 172 SLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEP 231
S S R+P R + ER P + PG SPG + T P P
Sbjct: 82 SAGTSSRNPASRPPASGRGERAP---------PAKNTSPGPVSSPGRASGTT----RPGP 128
Query: 232 DSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPL 291
++ + ++ + P+ L A A S P P P A +
Sbjct: 129 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAGTEV 187
Query: 292 GEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQ 351
G P +P G P S + +P P P Q
Sbjct: 188 GLPRPAPSARPRPPTEG------------PRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 352 QPLGHC------PLAEPLRLDLCSPHGPPGPEGHPKY----ALRRTDRPKILCRRRKAG- 400
+P PL+ P R S G P HP L+ P++ R+ A
Sbjct: 236 RPASRSLSSSATPLSSPARSGP-SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 401 ---------------RGRKADA--GPEGRLLPLPM------PTGLVAALAEPPPPPPPPP 437
G KA P+ PLP P LA P P PP
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Query: 438 PALPGPGPVSVPELKPESSQTP 459
LP P P + P P S TP
Sbjct: 355 QTLPSP-PATPPSQAPPSMTTP 375
Score = 32.7 bits (73), Expect = 2.9
Identities = 52/241 (21%), Positives = 75/241 (31%), Gaps = 57/241 (23%)
Query: 404 KADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGP----GPVSVPELKPESSQT- 458
KA AG R P GL+ PP P PPPP P G KP + +
Sbjct: 7 KAKAGAAART-PAARAPGLLTP--RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 459 -------PVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGK---- 507
P + R G R A P + GR + ++ +S G+
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 508 -------ELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPG- 559
+ GLR+SAE T + + K PK L G
Sbjct: 124 TRPGPLGQKGLRISAEET-----------------------VARGKATEAPKRSALSAGA 160
Query: 560 -------KPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEY 612
P P+ A + A + +P R + P+ S ++ + S E
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
Query: 613 S 613
S
Sbjct: 221 S 221
Score = 32.7 bits (73), Expect = 2.9
Identities = 66/255 (25%), Positives = 83/255 (32%), Gaps = 49/255 (19%)
Query: 860 SRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAG-------ADPSFQ 912
S P S A+ PP ALP + + P SP+A S A F
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPLQAPPS-PPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 913 PVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPAN---TYLP 969
P S P AS ++P+A+ A P L PP + SP PP + T P
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAP--PSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 970 QYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPC 1029
Q A + P P PASP + SA PPP P
Sbjct: 725 QAPPPLAAPPLQVPPSP----------------------PASPPMSPSA--TPPPRVPPL 760
Query: 1030 L-------PPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAA 1082
L PPS + S A AP L + SP P A +
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSP-----PASFPGQAPFSP 815
Query: 1083 SAASSSSSSFQPSPE 1097
SA+ S P P+
Sbjct: 816 SASLPMSPLATPPPQ 830
Score = 31.2 bits (69), Expect = 8.4
Identities = 65/259 (25%), Positives = 88/259 (33%), Gaps = 27/259 (10%)
Query: 859 ASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAG---ADPSFQPVL 915
AS P S A+ PP A P + + P SP+A A A P Q +
Sbjct: 743 ASPPMSPSATPPPRVPPLLAAPPLQ-VPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801
Query: 916 SARQTFPPGRA-----ASYGLTPAASDCRAAETF---PKLVPPPSAMARSPTTHPPANTY 967
S +FP G+A AS ++P A+ A P L PPS A SPT P
Sbjct: 802 SPPASFP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPP 859
Query: 968 LPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSA-----GYAP 1022
P +G + P + S + SG L SSA S GY
Sbjct: 860 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL---SGPDLAGHSSSATSTPEELRGYDS 916
Query: 1023 PPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGT-----TAS 1077
P GG P + ++ A +S PL P G+ T
Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 976
Query: 1078 ATSAASAASSSSSSFQPSP 1096
T +A+ + + P P
Sbjct: 977 ETEGPESATPAPGALDPGP 995
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 70.5 bits (171), Expect = 1e-11
Identities = 120/469 (25%), Positives = 170/469 (36%), Gaps = 44/469 (9%)
Query: 6 QGLVVTSSAVC--SSPDYLREPKYYPGGPPTPRPLLPTRP-PASPPDKAFSTHAFSENPR 62
QG+ + SAV ++PD L +P P+L +P P +PP A ST P
Sbjct: 584 QGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPP--AVST------PL 635
Query: 63 PPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVV 122
P + P ++PP P P AA P + P+P G SS + + P
Sbjct: 636 PLGLQQPQAQQPP-----QAPTPQAAAPPQATTPQPSP-GLASSPEKIVLGQPPSATPTA 689
Query: 123 QL----IDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIR 178
L + + R Q L G HL + P PP D + + +
Sbjct: 690 ILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP-PPAQDPAPATPVAKGAGLGPQ 748
Query: 179 SPEERATPHAKSERP-SHPLYEPEPE-----PRDSPQPGQGH--SPGATAAATGLPPEPE 230
+P+ +A+P + P + PL P P P +P H SP T + P P+
Sbjct: 749 APDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQ 808
Query: 231 PDSTDYSELADADILSELASLTCPEAQLLEAQ-ALEPPSPEPEPQLLDPQPRFLDPQALE 289
S SE A T P +++ Q + PP+ P P P L PQ+
Sbjct: 809 SVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQP 868
Query: 290 PLGEALELPPLQPLADPLGLPGLALQALDTLPDSLES--QLLDPQALDPLPKLLDVPGRR 347
P G P L P + + + + LP S QL P + P P
Sbjct: 869 PEGPLPPAPHLPPSSTSSAVAS-SSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLH 927
Query: 348 L--EPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDR-PKILCRRRKAGRGRK 404
L EP P P P + + P P+ PK L R + P + + KAG G
Sbjct: 928 LVPEPAAP----PPPPPRTFQMVTTPFPALPQ--PKALLERFHQVPSGIILQNKAG-GAP 980
Query: 405 ADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKP 453
A L PL P V + P P P P P P++ L P
Sbjct: 981 AAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPP 1029
Score = 53.1 bits (126), Expect = 2e-06
Identities = 84/326 (25%), Positives = 119/326 (36%), Gaps = 64/326 (19%)
Query: 155 PPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGH 214
P APP S L ++ P+ + P A + + + P P+P PG
Sbjct: 625 PQAPPA--------VSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQP----SPGLAS 672
Query: 215 SPGATAAATGLPPEPEP------DSTDY---SELADADILSELASLTCPEAQLLEAQALE 265
SP G PP P DS E + + +E L+ P + ++ A
Sbjct: 673 SP--EKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP--- 727
Query: 266 PPSPEPEPQLLDPQPRFLDPQALEPLGEALELP-PLQPLADPLGLPGLALQALDTLPDSL 324
PP+ +P P + L PQA P +A P P P A PL PG + + +LP
Sbjct: 728 PPAQDPAPATPVAKGAGLGPQA--PDSQASPAPAPQIPAAAPLKGPGPS--SSPSLPH-- 781
Query: 325 ESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYAL 384
++ L D L P P P R Q + P PL H P P+ P
Sbjct: 782 QAPLGDSPHL-PSPHPTRPPSRPPSRPQSVSRPPSEPPL-------HPCPPPQAPPTL-- 831
Query: 385 RRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPG 444
P I + + G +P P A A PP PP P + P G
Sbjct: 832 -----PGIFVIQNQLG---------------VPPPASNPAPTAPGPPQPPLRPQSQPPEG 871
Query: 445 PV-SVPELKPESSQTPVVSTRKGKCR 469
P+ P L P S+ + V S+ + R
Sbjct: 872 PLPPAPHLPPSSTSSAVASSSETSSR 897
Score = 37.7 bits (86), Expect = 0.090
Identities = 56/257 (21%), Positives = 85/257 (33%), Gaps = 56/257 (21%)
Query: 417 PMPTGLVAALAEPPPPPPPPPP------ALPGPGPVSVPELKP--ESSQTPVVSTRKGKC 468
P P +AEPPP PPPPPP P + PE KP + P + RK
Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRK--- 1389
Query: 469 RGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPL-LKMKNNG 527
TY+ ++ + EG G P PL K+
Sbjct: 1390 -----------------------TYR-ENVGGPGAPEGTPAGRARGGSPAPLPAKVDEAT 1425
Query: 528 RNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMPEVKKR 587
++ E + + +G PP EPA AA+ P +
Sbjct: 1426 SGLIRELAAVEDELYQRMLKGPPP-----------EPAASAAQG--TGDPDWEAPGLPPA 1472
Query: 588 RRRKQKLAS-PQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPP------RCWTP 640
+RRK + Q S+++D+ + + + + Q GR P TP
Sbjct: 1473 KRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTP 1532
Query: 641 SEPESVHQAPDTQSISH 657
+ P +H+ SH
Sbjct: 1533 ASPPPLHRPEAYPPSSH 1549
Score = 35.0 bits (79), Expect = 0.58
Identities = 47/175 (26%), Positives = 60/175 (34%), Gaps = 18/175 (10%)
Query: 1436 HAAAAQAH-LSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADF-LG 1493
H+ A AH LS + +GQP A P S P G T +L L
Sbjct: 533 HSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQS---QPAPAGPAATTVLQGVTLP 589
Query: 1494 RTEAACLSAPHLASPPATPKA---DKEPLEMARPP--GPPRGPAAAAAGYGCPLLSDLTL 1548
+ A L+ P PATP A + P+ +P PP G P
Sbjct: 590 PSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQ 649
Query: 1549 SPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL 1603
+P P+ + P T PQ PGL P+ LG P T SL
Sbjct: 650 APTPQAAAPPQATT--------PQPSPGLASSPEKIVLGQPPSATPTAILTQDSL 696
Score = 34.3 bits (77), Expect = 1.00
Identities = 67/266 (25%), Positives = 90/266 (33%), Gaps = 61/266 (22%)
Query: 872 AGPPTSALPAQR-GLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASYG 930
A PP + P GLA+ P + P + + S Q L ++ P A
Sbjct: 656 AAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPH 715
Query: 931 LTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQ 990
L+ AS +A PP A +P T P A GAG AP +
Sbjct: 716 LSVPASVIVSA--------PPPAQDPAPAT-PVAK---------GAGLGPQAPDSQASPA 757
Query: 991 DCANSKDCSFAYGSGNSLPASPSSAHSAGY-------APPPTGGPCLPPSKASFFSSSEG 1043
+ G G S +SPS H A +P PT P PPS+ S
Sbjct: 758 PAPQIPAAAPLKGPGPS--SSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPS 815
Query: 1044 -----------------------------APFSGSAPT---PLRCDSRASTVSPGGYMVP 1071
P S APT P + R + P G + P
Sbjct: 816 EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPP 875
Query: 1072 -KGTTASATSAASAASSSSSSFQPSP 1096
S+TS+A A+SS +SS P+P
Sbjct: 876 APHLPPSSTSSAVASSSETSSRLPAP 901
Score = 31.6 bits (70), Expect = 6.5
Identities = 49/192 (25%), Positives = 71/192 (36%), Gaps = 19/192 (9%)
Query: 926 AASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTK 985
A GL P A D +A+ P P A A P ++ LP G + +P
Sbjct: 740 AKGAGLGPQAPDSQAS---PAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSP-H 795
Query: 986 PFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAP 1045
P S+ S S P S H PPP P LP P
Sbjct: 796 PTRPPSRPPSRPQSV------SRPPSEPPLHPC---PPPQAPPTLPGIFVIQNQLGVPPP 846
Query: 1046 FSGSAPT---PLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQ---PSPENC 1099
S APT P + R + P G + P ++++++ ASSS +S + P+P +
Sbjct: 847 ASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906
Query: 1100 RQFAGASQWPFR 1111
+ SQ P +
Sbjct: 907 QLQFPPSQGPHK 918
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 69.3 bits (168), Expect = 3e-11
Identities = 125/529 (23%), Positives = 190/529 (35%), Gaps = 83/529 (15%)
Query: 5 PQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASP----PDKAFSTHAFSEN 60
P+ VT V +P + K P PP + PT+ P P P+K +
Sbjct: 10599 PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKP 10658
Query: 61 PRPPPR-----RDPSTRRPP--VLAKGDDPLPPRAA----RPVSQARCPTPVGDGSSSRR 109
PPP + + PP V+ + + PP+ +PV + + P V
Sbjct: 10659 ESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPEL-- 10716
Query: 110 CWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFS 169
P V++ ++ K++ + V L + +P APP +
Sbjct: 10717 ----------PPVKVPEVPKEV------VPEKKVPL----VVPKKPEAPPAKVPEVPKEV 10756
Query: 170 SPSLANSIRSPEERATPHAK-SERPSHPLYE-----PEPEPRDSPQPGQGHSPGATAAAT 223
P + P++ P AK E P P+ E P PE +SP P P A
Sbjct: 10757 VPE--KKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEE 10814
Query: 224 GLPPE---PEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSP-EPEPQLLDPQ 279
+ PE P P + + + E PE ++ + E P P EPEP+ + +
Sbjct: 10815 EIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEK 10874
Query: 280 PRFLDPQALEPLGEALELPPLQPLADPL-------GLPGLALQALDTLPDSLE-SQLLDP 331
P+ L P+ P PP P D +P + +P+ +E + L P
Sbjct: 10875 PK-LKPRPPPP-------PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVP 10926
Query: 332 QALDPLPKLLDVPGRRLEPQQ-----------PLGHCPLAEPLRLDLCSPHGPPGPEGHP 380
+ KLL P R+ EP++ P P EP +L+ P PE P
Sbjct: 10927 GGEKKVRKLL--PERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKK--PAVPEPPP 10982
Query: 381 KYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPAL 440
+ + P + R RK K LP P P A + PPP P
Sbjct: 10983 PKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT 11042
Query: 441 PGPGPVSVPEL-KPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRR 488
P PV+VP + K ++ P K K G + V K P+ RR
Sbjct: 11043 PIAAPVTVPVVGKKAEAKAPKEEAAKPK--GPIKGVPKKTPSPIEAERR 11089
Score = 43.5 bits (101), Expect = 0.002
Identities = 90/453 (19%), Positives = 154/453 (33%), Gaps = 95/453 (20%)
Query: 154 RPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQG 213
+P APP G P ++ I P++ T + P P PE +
Sbjct: 10435 KPKAPPKG---------PEISEKIIPPKKPPTKVVPRKEP--PAKVPEVPKKI------- 10476
Query: 214 HSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPE- 272
+P EP T E+ P+ + E + PP+ +PE
Sbjct: 10477 ----VVEEKVRVPEEPRVPPTKVPEVLP------------PKEVVPEKKVPVPPAKKPEA 10520
Query: 273 -PQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDP 331
P + P+ + P+ P+ PP +P P +P + A+ P+ + + P
Sbjct: 10521 PPPKVPEAPKEVVPEKKVPVP-----PPKKPEVPPTKVPEVPKAAV---PEKKVPEAIPP 10572
Query: 332 QALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPK 391
+ P P++ + P + + P++ + P +P + P P K + +P+
Sbjct: 10573 KPESPPPEVPEAP-KEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPE 10631
Query: 392 ILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPEL 451
+ K P+ + +P + PP P PPP P V++ E
Sbjct: 10632 V--------PPTKVPEVPKVAVPEKKVPEAI------PPKPESPPPEVFEEPEEVALEEP 10677
Query: 452 KPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGL 511
E + P + V K PV E K +
Sbjct: 10678 PAEVVEEPEPAAPP--------QVTVPPKKPVP--------------------EKKAPAV 10709
Query: 512 RVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKE--PAVVAA 569
P +K+ + VV P ++P+++ +K PP + P PKE P A
Sbjct: 10710 VAKKPELPPVKVPEVPKEVV---PEKKVPLVVPKKPEAPPAKV---PEVPKEVVPEKKVA 10763
Query: 570 EAATVAAATMAMPEVKKRRRRKQKLASPQPSYA 602
+PEV K+ ++K A P P A
Sbjct: 10764 VPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERA 10796
Score = 42.4 bits (98), Expect = 0.004
Identities = 60/294 (20%), Positives = 101/294 (34%), Gaps = 52/294 (17%)
Query: 29 PGGPPTPRPLLPTRP------PASPPDKAFSTHAFSENPRPPPRRDPSTRRPP------- 75
P P P+ ++P + P +PP K E P+ PR P PP
Sbjct: 10837 PAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEK 10896
Query: 76 -----VLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKD 130
+ K P P+ V P G+ + + +P + ++K
Sbjct: 10897 IFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPER-----KPEPKEEVVLKS 10951
Query: 131 LTRLSQDLQHSGVH---LDCGGLRLSRPPAP-PPGDLQYSFFSSPSLANSIRS-PEERAT 185
+ R + + V L+ ++ +P P PP P++ R PE
Sbjct: 10952 VLRKRPEEEEPKVEPKKLE----KVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKV 11007
Query: 186 PHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADIL 245
P K P+ PL PEP+P+ + T PP EP+ T + ++
Sbjct: 11008 PEIK---PAIPLPAPEPKPKPEAE-----------VKTIKPPPVEPEPTPIAAPVTVPVV 11053
Query: 246 SELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPP 299
+ A P+ + + + P+ P ++ + R L P G E PP
Sbjct: 11054 GKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRP------GSGGEKPP 11101
Score = 38.5 bits (88), Expect = 0.053
Identities = 73/360 (20%), Positives = 134/360 (37%), Gaps = 50/360 (13%)
Query: 255 EAQLLEAQALEPPSPEPEPQLLDPQ--PRFLDPQALEPLGEALELPPLQPLADPLGLPGL 312
E ++ E P PE +++ P+ P + P+ EP + E+P + + + +P
Sbjct: 10429 EVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRK-EPPAKVPEVPKKIVVEEKVRVP-- 10485
Query: 313 ALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHG 372
+P + ++L P+ + P K+ P ++ P A P ++ P
Sbjct: 10486 ---EEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKK----------PEAPPPKV----PEA 10528
Query: 373 PPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPP 432
P K + +P++ K P+ + +P + PP
Sbjct: 10529 PKEVVPEKKVPVPPPKKPEV--------PPTKVPEVPKAAVPEKKVPEAI-------PPK 10573
Query: 433 PPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTT 492
P PPP +P VPE K ++ K + VV K+PV ++ +
Sbjct: 10574 PESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP 10633
Query: 493 YKVSSLSSSLSVEGKELGLRVSAEP-TPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPP 551
++V K++ + +P +P ++ V + PP E +++ P
Sbjct: 10634 PTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAE---VVEEPEPAAP 10690
Query: 552 KNLLLGPGKP----KEPAVVAAEAATVAAATMAMPEVKKR--RRRKQKLASPQPSYAADA 605
+ + P KP K PAVVA + + +PEV K +K L P+ A A
Sbjct: 10691 PQVTVPPKKPVPEKKAPAVVAKKP---ELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPA 10747
Score = 32.7 bits (73), Expect = 2.9
Identities = 46/196 (23%), Positives = 73/196 (37%), Gaps = 28/196 (14%)
Query: 415 PLPMPTGLVAALAEPP--PPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVR 472
P+P+P + + P P P P P P P P P+ + P
Sbjct: 9302 PVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVP------------- 9348
Query: 473 RMVVKMAKIPVSLGRRNKT-TYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVV 531
+ V KIPV + ++ + KV + + E K + + E +P + + V
Sbjct: 9349 KKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEK-ITIVTQREESPPPAVPEIPKKKV 9407
Query: 532 VVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMP---EVKKRR 588
P P+ K + PP + P PK+P A V A A P EV K+
Sbjct: 9408 ---PEERKPVPRKEEEVPPPPKV---PALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKT 9461
Query: 589 --RRKQKLASPQPSYA 602
K+ +A + S+A
Sbjct: 9462 VVEEKRFVAEEKLSFA 9477
Score = 31.2 bits (69), Expect = 8.4
Identities = 65/274 (23%), Positives = 100/274 (36%), Gaps = 25/274 (9%)
Query: 331 PQALDPLP-KLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDR 389
P +P+P K P + L+ P P+ P +L P P PE PK R
Sbjct: 9797 PVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKL---KPPPPKVPE-EPKKVFEEKIR 9852
Query: 390 PKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVP 449
I R ++ A +PM V A + P P P PV VP
Sbjct: 9853 ISITKREKEQVTEPAAK---------VPMKPKRVVAEEKVPVPRKEVAP------PVRVP 9897
Query: 450 ELKPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKEL 509
E+ P+ + V+ + V +V+ + + T +V + E
Sbjct: 9898 EV-PKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRK 9956
Query: 510 GLRVSAEPTPLLKMKNNGRNVVVVFP--PGE-MPIILKRKRGRPPKNLLLGPGKP-KEPA 565
+ +P P+ K K V P P E +P+++ +K PP + P KP E
Sbjct: 9957 PVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEK 10016
Query: 566 VVAAEAATVAAATMAMPEVKKRRRRKQKLASPQP 599
V V A +PEV K+ ++K+ P P
Sbjct: 10017 VPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAP 10050
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 65.9 bits (159), Expect = 3e-10
Identities = 129/515 (25%), Positives = 166/515 (32%), Gaps = 101/515 (19%)
Query: 31 GPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAAR 90
G P P P RPP P K+ S+ + P P+ RR P G L A+R
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP----SPAARRRPSAGGG---LQRPASR 231
Query: 91 PVSQARCP--TPVGDGSSSR----------RCWDNGRVNLRPVVQLIDIMKDLTRLSQDL 138
+S + P +P G S+R + G LRP Q+ KD L
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP-QVTPPRKDAAPALGPL 290
Query: 139 QHSGVHLDCGGL-----------RLSRPPAPPPGDLQ-----------YSFFSSPSLANS 176
S + L PPA PP +SF SP L+
Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS-P 349
Query: 177 IRSPEERATPHAKS---ERPSHPLYEPEPEPRDSPQPGQGHSPGATAA----ATGLPPEP 229
+ +P +A P + P P P P +P P +P A A A PP
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP---QAPNALAVHLLQAPFSPPPS 406
Query: 230 EPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQL---LDPQPRFLDPQ 286
P +S A + + L PPSP P + P P+ P
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 287 ALEPLG---------EALELPPLQPL-ADPLGLPG---------LALQALDTLPDS---- 323
A PL AL PPLQ L + P PG L + L T P
Sbjct: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Query: 324 LESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYA 383
L + LL P L P R P P ++ P +P PP P P
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583
Query: 384 LRRTDRPKILCRRRKAGRG-RKADAGPEGRLLPLPMPTGLVAAL-----AEPPPPP---- 433
L D R D+GPEG P P +AA + P PP
Sbjct: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 643
Query: 434 -----PPPPPALPGPGPV----SVPELKPESSQTP 459
P P P GPG ++ E + S TP
Sbjct: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678
Score = 61.6 bits (148), Expect = 6e-09
Identities = 107/452 (23%), Positives = 143/452 (31%), Gaps = 69/452 (15%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN---------PRPPPRRDPS-TRRPPVLA 78
PG P P P+ P A +E P PR P+ T RPP
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASG 89
Query: 79 KGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLR-PVVQLIDIMKDLTRLSQD 137
+G+ P A+ S +P G S + R G+ LR + + K +
Sbjct: 90 RGERAPP---AKNTSPGPVSSP-GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145
Query: 138 LQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPS--- 194
+G D G P P P + S + + +P R P + R S
Sbjct: 146 ALSAGARRDTSG---PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202
Query: 195 ---HPLYEPEPEPRDSPQPGQG-HSPGATAAATGLPPEPEPDSTDYSELADADILSELAS 250
H EP P R P G G P + + ++ P P + S + +
Sbjct: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262
Query: 251 LTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLP 310
P+ + L QAL PP P + P L P + PL P P A P
Sbjct: 263 ---PKPKGL--QALRPPQVTPPRKDAAPA---LGPLSSSPLATPSPSAPPSPSAPP---- 310
Query: 311 GLALQALDTLPDSLESQL---LDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDL 367
+LQ L + P + SQ L L L P P PL P P L L
Sbjct: 311 --SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP-----PLSPLATPPPQAPPALAL 363
Query: 368 CSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALA 427
PP P P + T P+ P + L+ A
Sbjct: 364 PPLQAPPSPPASPPLSPLATPSPQA----------------------PNALAVHLLQAPF 401
Query: 428 EPPPPPPPPPPALPGPGPVSVPELKPESSQTP 459
PPP PP P P P P P S P
Sbjct: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Score = 50.1 bits (118), Expect = 2e-05
Identities = 95/368 (25%), Positives = 121/368 (32%), Gaps = 58/368 (15%)
Query: 1244 ASHLGFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVN 1303
A +G T +A P++ S R P GRG A AK G +
Sbjct: 62 AGGIGGATIPESAPRAGPTRTS---RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 118
Query: 1304 PLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGF 1363
PL Q + + + P +S A G R D GP P TPS +
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRS-ALSAGARR--DTSGP---TPGTPSPA-MARRS 171
Query: 1364 HCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTC--SPTLGFKEELRPPPTKLAA 1421
+G P P PPT G +K+ S S T R P
Sbjct: 172 RAAGTEVGLPRPAPSARP---RPPT---EGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 225
Query: 1422 CEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEG 1481
P L ++ ++ A++ S R P H P KG PP +PP
Sbjct: 226 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV---TPP--- 279
Query: 1482 KVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARP-----PGPPRG-PAAAA 1535
R +AA P +SP ATP P A P P PP P+ A
Sbjct: 280 ------------RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327
Query: 1536 AGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLG--------GGPKSGFLG 1587
G P L T S +P L PL PQA P L P S L
Sbjct: 328 TSLGSPTL-QATHSFLPSPPLSPLATPP-------PQAPPALALPPLQAPPSPPASPPLS 379
Query: 1588 PMAEPHPE 1595
P+A P P+
Sbjct: 380 PLATPSPQ 387
Score = 49.7 bits (117), Expect = 2e-05
Identities = 92/348 (26%), Positives = 119/348 (34%), Gaps = 59/348 (16%)
Query: 25 PKYYPGGPPTPRPLLPTRPPASPPDKAFSTH----AFSENPRPP--------------PR 66
P P PP PL P P+ A + H FS P PP P
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 67 RDPSTRRPPVLAKGDDPLPPR--AARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQL 124
P ++ PP LA +PP A+ P+S + P P + P +QL
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-----------APPLQL 473
Query: 125 IDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANS-IRSPEER 183
K + L + L PPA PG Q F S SL S + +P +
Sbjct: 474 ---AKPPPQAPPALATPPLQ------ALPSPPASFPG--QAPFSPSASLPMSPLATPPPQ 522
Query: 184 ATPHAKSE----RPSHPLYEPEPEPRDSPQPGQGHS---PGATAAATGLPPEPEPDSTDY 236
A P + PS P PR P PG S P T A PP P P +
Sbjct: 523 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPSRSPS 581
Query: 237 SELADADILSELASLTCPEAQL----LEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLG 292
S L+ D+ +S T +L + SP P+ +L P PL
Sbjct: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL- 640
Query: 293 EALELPPLQPLADPLGLPGLALQALDTL--PDSLESQLLDPQALDPLP 338
A P PL P + L T+ + ES P ALDP P
Sbjct: 641 -AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687
Score = 48.1 bits (113), Expect = 7e-05
Identities = 134/606 (22%), Positives = 190/606 (31%), Gaps = 102/606 (16%)
Query: 1015 AHSAGYAPPPTGGPCLPPSKASFFSSS----EGAPFSGSAPTPLRCDSRASTVSPGGYMV 1070
A G A P P P++ S +S P ++P P+ RAS + G +
Sbjct: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121
Query: 1071 PKGTTASATSAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNP 1130
KG SA + ++ + P+ AGA + G A S+
Sbjct: 122 QKGLRISAEETVARGKATEA-----PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 1131 SFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEAS 1190
P+ P+K ++ SE + S + + +P GGG +R S +
Sbjct: 177 EVGLPRPAPSARPRPPTEGPRK--SVSSASEHSTTEPSPAAR-RRPSAGGGLQRPASRSL 233
Query: 1191 SSEGQSSLSSLEKLMMDWNEASSAPGYNWN------QSVLFQSSSKPGRGRRKKVDLFEA 1244
SS + LSS + AP + Q++ + P + + +
Sbjct: 234 SSSA-TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292
Query: 1245 SHLGFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNP 1304
S L P+ ++ + P T P P S A F+P P P++P
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT--LQATHSFLPSP-PLSP 349
Query: 1305 LF----QDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFI-----GPYSMNPSTPS 1355
L Q P L L S P S + P P+S PS P
Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 409
Query: 1356 DGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPP 1415
F SP +P + PP PP++ LQ SP SP + PP
Sbjct: 410 QAPF-------SPP-ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM--SPSATPP 459
Query: 1416 PTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAAR 1475
P A L+ L L +P +P T PP A
Sbjct: 460 P----------------------QAPPPLAAPPLQLAKPPPQAPPALAT----PPLQALP 493
Query: 1476 SPPYEGKVGTGLLADFLGRT----EAACLSAPHLASPPATPKADKEPLEMARPPGPPRGP 1531
SPP A F G+ A+ +P PP P PL + PP PP P
Sbjct: 494 SPP----------ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASP 542
Query: 1532 AAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYP----GFMPQAHPGLGGGPKSGFLG 1587
A PR P DT+ P P P P S G
Sbjct: 543 TLQA----------------PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 586
Query: 1588 PMAEPH 1593
P H
Sbjct: 587 PDLAGH 592
Score = 44.3 bits (103), Expect = 0.001
Identities = 69/277 (24%), Positives = 91/277 (32%), Gaps = 47/277 (16%)
Query: 25 PKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPV-LAKGDDP 83
P P P +P PPASPP S + PPP+ P PP+ LAK
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPP--------MSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 84 LPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVV--------------------- 122
PP A P QA P+P + + + P+
Sbjct: 480 APPALATPPLQA-LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538
Query: 123 ---QLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLA----N 175
+ + D SG L L L+ P PPP S S P LA +
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSGPRLT---LALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595
Query: 176 SIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLP--PEPEPDS 233
+ +PEE + E + P+ E P A G P P P P +
Sbjct: 596 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655
Query: 234 TDYSELADADILSELASLTCPEAQLLEAQALEP-PSP 269
T AD L + PE+ AL+P PSP
Sbjct: 656 TG---PGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 42.7 bits (99), Expect = 0.003
Identities = 64/221 (28%), Positives = 84/221 (38%), Gaps = 28/221 (12%)
Query: 889 PSRGAKASPVAVGSSGAGADPSFQ--PVLSARQT-FPPGRAASYGLTPAASDCRAAETFP 945
P A SP A A P Q P L+A PP AS ++P+A+ A P
Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP--P 464
Query: 946 KLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSG 1005
L PP +A+ P PPA P Q++ +P F GQ +
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPL-------QALPSPPASFPGQ---------APFSPS 508
Query: 1006 NSLPASPSSAHSAGYAPPPTGGPCL--PPSKASFFSSSEGAPFSGSAPTPLRCDS--RAS 1061
SLP SP A APP P L PPS + S + AP P P S R +
Sbjct: 509 ASLPMSP-LATPPPQAPPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSGPRLT 565
Query: 1062 TVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQF 1102
G P + S+T + + SSS +PE R +
Sbjct: 566 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606
Score = 39.7 bits (91), Expect = 0.024
Identities = 53/209 (25%), Positives = 70/209 (33%), Gaps = 11/209 (5%)
Query: 860 SRPESRKASGTYAGPPTSALPAQRGLATFPSRGA-KASPVAVGSSGAGADPSFQPVLSAR 918
+ P K G A P P ++ A P+ G +SP+A S A PS P L
Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDAA--PALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Query: 919 QTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQ 978
+ PP S T S A PP S +A P PPA P
Sbjct: 316 PS-PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 374
Query: 979 SVFAPTKPFT--GQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKAS 1036
S P P N+ + P+ P A + A PP PPS+A
Sbjct: 375 S--PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA- 431
Query: 1037 FFSSSEGAPFSGSAPTPLRCDSRASTVSP 1065
S AP P+P + + +P
Sbjct: 432 --PPSLAAPPLQVPPSPPASPPMSPSATP 458
Score = 36.6 bits (83), Expect = 0.20
Identities = 59/231 (25%), Positives = 80/231 (34%), Gaps = 38/231 (16%)
Query: 868 SGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAA 927
S AGP ++ P G RG +A P S G + P A T PG
Sbjct: 73 SAPRAGPTRTSRPPASG------RGERAPPAKNTSPGPVSSPG-----RASGTTRPGPLG 121
Query: 928 SYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPF 987
GL +A + +AR T P + L GA + PT
Sbjct: 122 QKGLRISAEE---------------TVARGKATEAPKRSALSA----GARRDTSGPTPGT 162
Query: 988 TGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFS 1047
A S A G+ LP SA PPT GP S AS S++E +P +
Sbjct: 163 PSPAMARR---SRAAGTEVGLPRPAPSARPR----PPTEGPRKSVSSASEHSTTEPSPAA 215
Query: 1048 GSAPTPLRCDSRASTVSPGGYMVPKGTTA-SATSAASAASSSSSSFQPSPE 1097
P+ R ++ S P + A S SA + + QP P+
Sbjct: 216 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266
Score = 33.1 bits (74), Expect = 2.2
Identities = 56/241 (23%), Positives = 75/241 (31%), Gaps = 66/241 (27%)
Query: 404 KADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALP---------------------- 441
KA AG R P GL+ PP P PPPP P
Sbjct: 7 KAKAGAAART-PAARAPGLLTP--RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 442 GPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVK-MAKIPVSLGRRNKTTYKVSSLSS 500
G G ++PE P + T S RG R K + PVS R T + L
Sbjct: 64 GIGGATIPESAPRAGPTR-TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG- 121
Query: 501 SLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPG- 559
+ GLR+SAE T + + K PK L G
Sbjct: 122 -------QKGLRISAEET-----------------------VARGKATEAPKRSALSAGA 151
Query: 560 -------KPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEY 612
P P+ A + A + +P R + P+ S ++ + S E
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211
Query: 613 S 613
S
Sbjct: 212 S 212
Score = 32.7 bits (73), Expect = 2.9
Identities = 66/255 (25%), Positives = 88/255 (34%), Gaps = 30/255 (11%)
Query: 860 SRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQ 919
S P S S + PP + P LA P + AK P A A A P Q + S
Sbjct: 445 SPPASPPMSPSATPPPQAPPP----LAAPPLQLAKPPPQA---PPALATPPLQALPSPPA 497
Query: 920 TFPPGRA-----ASYGLTPAASDCRAAETF---PKLVPPPSAMARSPTTHPPANTYLPQY 971
+FP G+A AS ++P A+ A P L PPS A SPT P P
Sbjct: 498 SFP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPPTPGP 555
Query: 972 GGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSA-----GYAPPPTG 1026
+G + P + S + SG L SSA S GY P G
Sbjct: 556 DTSVSGPRLTLALAPGPPPPPSRSPSSTL---SGPDLAGHSSSATSTPEELRGYDSGPEG 612
Query: 1027 GPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGT-----TASATSA 1081
G P + ++ A +S PL P G+ T T
Sbjct: 613 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 672
Query: 1082 ASAASSSSSSFQPSP 1096
+A+ + + P P
Sbjct: 673 PESATPAPGALDPGP 687
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 65.9 bits (159), Expect = 3e-10
Identities = 99/377 (26%), Positives = 135/377 (35%), Gaps = 59/377 (15%)
Query: 61 PRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRP 120
P PPP P PP L G P PP +A PVS D SS RR GR L
Sbjct: 2 PVPPPPPPPLPPPPPPL--GAPPPPPPSAPPVST--------DTSSLRRADPKGRSALLA 51
Query: 121 VVQLIDIMKDLTRLS-----QDLQHSGVHLDCGGLRLSRPPAPPP--GDLQYSFFS--SP 171
+Q ++ +T+++ Q G + + GG +R + PP GDL F P
Sbjct: 52 DIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRP 111
Query: 172 SLANSI------RSPEERA-TPHAKSERPSHPLYEP---------EPEPRDSPQPGQGHS 215
+ + + P RA +P ++ S PL P E P + +
Sbjct: 112 AGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNV 171
Query: 216 PGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLE--AQALEPPSPEPEP 273
P PP P P S ++S LT ++ PP P P P
Sbjct: 172 PAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPP 231
Query: 274 QLLDPQP--RFLDPQALEPLGEALELPPLQ---PLADPLGLPGLALQALDTLPDSLESQL 328
P P L +A++P L LPP+ PL P G PGL + D+ E
Sbjct: 232 PTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPA 291
Query: 329 ----------LDPQALDPLPKLLDVPGRR-----LEPQQPLGHCPLAEPLRLDLCSPHGP 373
P+A P P L V L P+ P P + L +P P
Sbjct: 292 PPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP 351
Query: 374 PGPEGHPKYALRRTDRP 390
PG + P +R RP
Sbjct: 352 PGSQ--PFLQKKRHGRP 366
Score = 42.4 bits (98), Expect = 0.004
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 5/65 (7%)
Query: 402 GRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQT--- 458
G ++A R P P P PPPPPPP PP LP P+ P + P T
Sbjct: 153 GNTSEAHGAARTAP-PRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGN 211
Query: 459 -PVVS 462
PVV+
Sbjct: 212 LPVVA 216
Score = 39.7 bits (91), Expect = 0.024
Identities = 96/409 (23%), Positives = 130/409 (31%), Gaps = 56/409 (13%)
Query: 196 PLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPE 255
P+ P P P P P G P PP P STD S L AD A L +
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPP-------PPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
Query: 256 AQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQ 315
Q + + + PQ+ + + A P L L G P L
Sbjct: 55 -QGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAG-GFPVLRPA 112
Query: 316 ALDTLPDSLESQLLDPQALDPLPKLLD--VPGRRLEPQQP-LGHCPLAE------PLRLD 366
+ Q P + P P+L + + G + P P LG+ A P R +
Sbjct: 113 GQRDVAGGKTGQ--GPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPN 170
Query: 367 LCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAAL 426
+ +P P P P I + P G L +P
Sbjct: 171 VPAPPPPTPPPPPPPLPPPLPSSSPI----------KTPLVSPPGPLTKGNLPVVAPPVP 220
Query: 427 AEPPPPPPPPPPALPGPGPVSV-------PELKP---ESSQTPVVSTRKGKCRGVRRMVV 476
PPPPPPPPPP P P SV P+L P P+ G++
Sbjct: 221 CAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPA 280
Query: 477 KMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKEL-GLRVSAEPTPLLKMKNNGRNV----- 530
A+ +S S S+ L G+ S+E P L K+
Sbjct: 281 SPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKA 340
Query: 531 ------VVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAAT 573
PPG P + K++ GRP G GK P A + T
Sbjct: 341 GAQALPAPPAPPGSQPFLQKKRHGRPG----AGGGKLNPPPAPPARSPT 385
Score = 36.6 bits (83), Expect = 0.20
Identities = 17/43 (39%), Positives = 22/43 (51%), Gaps = 7/43 (16%)
Query: 414 LPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESS 456
+P+P P PP PPPPPP P P P S P + ++S
Sbjct: 1 MPVPPPP-------PPPLPPPPPPLGAPPPPPPSAPPVSTDTS 36
Score = 33.5 bits (75), Expect = 1.7
Identities = 23/75 (30%), Positives = 25/75 (33%), Gaps = 3/75 (4%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRP---PPRRDPSTRRPPVLAKGDDPLP 85
P PP P P P PP PP S A P PP P PP G P
Sbjct: 220 PCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP 279
Query: 86 PRAARPVSQARCPTP 100
A+ + P P
Sbjct: 280 ASPAQDAQEPPAPPP 294
Score = 32.3 bits (72), Expect = 3.8
Identities = 27/81 (33%), Positives = 30/81 (37%), Gaps = 13/81 (16%)
Query: 26 KYYPGGPPTPRPLLPTRPPASPPDKAFSTHA------------FSENPRPPPRRDPSTRR 73
K P P P PP PP + S A SE P P P + PS +
Sbjct: 276 KAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQA 335
Query: 74 PPVLAKGDDPLPPRAARPVSQ 94
PP A G LP A P SQ
Sbjct: 336 PPQKA-GAQALPAPPAPPGSQ 355
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 64.7 bits (156), Expect = 7e-10
Identities = 136/536 (25%), Positives = 176/536 (32%), Gaps = 118/536 (22%)
Query: 4 KPQGLVVTSSAVCSSPDYLREP-------KYYPGGPPTPRPLLPTR----------PPAS 46
K L+ + + C + + R+ K P P P+PLLP R PP
Sbjct: 685 KVAALLERTQSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEE 744
Query: 47 ----PPDKAFSTH---AFSENPRP---PPRRDPSTRRP-PVLAKGDDPLPP---RAARPV 92
PPD F + P PP PS+ P P G PLPP +
Sbjct: 745 LRSLPPDMVAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSG--PLPPGTYSGPTQL 802
Query: 93 SQARCP----TPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCG 148
Q R P PV G + L P + + R S QH V
Sbjct: 803 IQPRAPGPHAMPVAPGPA-----------LYPAPAYTPELGLVPRSSP--QHGVVSSPYV 849
Query: 149 GLR-----LSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPE 203
G+ P APPP FS P LA ++R P ++ PSH P P
Sbjct: 850 GVGPAPPVAGLPSAPPPQ------FSGPELAMAVR-PATTTVDSIQAPIPSHTA--PRPN 900
Query: 204 PRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQA 263
P +P P P PP+P P Y A I ++ + A +
Sbjct: 901 PTPAPPPPCFPVP---------PPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRI 951
Query: 264 LEPPSPEPEP---QLLDPQPRFLDPQALEPLGEALELPPLQP-LADPLGLPGLALQ--AL 317
P P P+P Q PQP PQ PL PP P L P A Q L
Sbjct: 952 GPQPQPHPQPHPSQAFGPQP----PQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVL 1007
Query: 318 DTLPDSLESQLLDPQALDPLPKLLDV-----PGRRLEPQQPLGHCPLAEPLRLDLCSPHG 372
P L +QL A DPLP PG P PL + P
Sbjct: 1008 GQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTR--------- 1058
Query: 373 PPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPP 432
P GP+ P L R + G+ P L+P P P+ + PP
Sbjct: 1059 PMGPQAAP------------LTIRGPSSAGQST---PSPHLVPSPAPSPGPGPVPPRPPA 1103
Query: 433 PPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRR 488
PPP G + PES S G + +++ K+ + GRR
Sbjct: 1104 AEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGG------QPLLQPTKVDAAEGRR 1153
Score = 34.7 bits (78), Expect = 0.76
Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 409 PEGRLLPLPMPTGLVAALAEPPPPPPPPP-PALPGPGPVSVPELKPESSQTPVVSTRKGK 467
PE +P P L + L E P P PP P P GP S L+ +S TP +
Sbjct: 1535 PESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPS-SSLELLASLTPEAFSLDSS 1593
Query: 468 CRGVRRM 474
RG +RM
Sbjct: 1594 LRGKQRM 1600
Score = 34.3 bits (77), Expect = 1.00
Identities = 41/133 (30%), Positives = 52/133 (39%), Gaps = 24/133 (18%)
Query: 871 YAGPPTSALPAQRGLATFPSRGAKA---SPVAVGSS------GAGADP-SFQPVLSARQT 920
Y GP LPA G FPS G P+A G + G A P + + SA Q+
Sbjct: 1019 YPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQS 1078
Query: 921 FP-----PGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGY- 974
P P A S G P AAE PPP + +++ Q+GG
Sbjct: 1079 TPSPHLVPSPAPSPGPGPVPPRPPAAE------PPPCLRRGAAAADLLSSSPESQHGGTQ 1132
Query: 975 --GAGQSVFAPTK 985
G GQ + PTK
Sbjct: 1133 SPGGGQPLLQPTK 1145
Score = 32.3 bits (72), Expect = 3.8
Identities = 44/149 (29%), Positives = 51/149 (34%), Gaps = 32/149 (21%)
Query: 1465 AYWYPPGSAARSPPYEGKV-----GTGLLADFLGRTEAAC--LSAPHLASP--PATPKAD 1515
AY G RS P G V G G G A S P LA PAT D
Sbjct: 826 AYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVD 885
Query: 1516 --KEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQA 1573
+ P+ P P PA + PVP LP T Y YP Q
Sbjct: 886 SIQAPIPSHTAPRPNPTPAPPPPCF-----------PVPPPQPLP---TPYTYPAGAKQP 931
Query: 1574 HPG---LGGGPKSGF----LGPMAEPHPE 1595
P G +GF +GP +PHP+
Sbjct: 932 IPAQHHFSSGIPAGFPAPRIGPQPQPHPQ 960
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 63.9 bits (154), Expect = 1e-09
Identities = 124/549 (22%), Positives = 171/549 (31%), Gaps = 141/549 (25%)
Query: 36 RPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQA 95
RP PP SP K + + S+ P P P PP P PP P+
Sbjct: 600 RPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPP-------PPPPPPPPPLPSQ 652
Query: 96 RCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRP 155
P+ GS++ + +TRL QHSG L +P
Sbjct: 653 SAPSA---GSAA---------------PMFVKYSTITRLQNASQHSGA--------LFKP 686
Query: 156 PAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHS 215
P PP S S+ I P P P P P P PG
Sbjct: 687 PTPP-------VMQSQSVKPQILVPPNGVVP-------------PPPPPPPPPTPG---- 722
Query: 216 PGATAAATGLPPEP-EPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQ 274
+A L P P P +S + ++ +T + PP+P P P
Sbjct: 723 ----SAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHIT----------QVAPPTPPPPPP 768
Query: 275 LLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQAL 334
+ P P P+ L + + P+ P +P + + +
Sbjct: 769 IPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPP----TPTPPVPPAKKQPAFPASYI 824
Query: 335 DPLPKL--LDVPGRRLEPQQ---------PLGHCP-LAEPLRLDLCSPHGPPGPEGHPKY 382
P P + VP L QQ PL P + + + P PP E P
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK 884
Query: 383 ALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPP------PP 436
+ P+ + P + P P+ + + PPPPP PP
Sbjct: 885 PVPANVAPQ---------------SPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP 929
Query: 437 PPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRR-NKTTYKV 495
PP P P P P P +S TP S GK K +K G++ T +
Sbjct: 930 PP--PSPVPAPPPPPPPTASPTPDKSGSPGK---------KTSKTSSPGGKKPPPTPQRN 978
Query: 496 SSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLL 555
SS+ SS E P P K + V PP E G P K L
Sbjct: 979 SSIKSSSGAE----------HPEP--KRPSVDSLVSKFTPPAE--------SGSPSKETL 1018
Query: 556 LGPGKPKEP 564
P P +P
Sbjct: 1019 PPPAAPPKP 1027
Score = 42.7 bits (99), Expect = 0.003
Identities = 65/279 (23%), Positives = 96/279 (34%), Gaps = 37/279 (13%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPP---RRDPSTRRPPVLAKGDDPLP 85
P PP P P+ PP +PP + A + P + P T PPV P
Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAF 819
Query: 86 PRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRL----------- 134
P + P S P PV + ++ + P+ + ++K +
Sbjct: 820 PASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME 879
Query: 135 SQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERAT--PHAKSER 192
SQ L+ ++ S P Q S PS PE P S
Sbjct: 880 SQPLKPVPANV----APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPV 935
Query: 193 PSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLP----PEPEP---------DSTDYSEL 239
P+ P P P P SP P + SPG + T P P P P ++ E
Sbjct: 936 PAPP---PPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP 992
Query: 240 ADADILSELASLTCP-EAQLLEAQALEPPSPEPEPQLLD 277
+ S ++ T P E+ + L PP+ P+P L+
Sbjct: 993 KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031
Score = 40.8 bits (94), Expect = 0.011
Identities = 71/314 (22%), Positives = 106/314 (33%), Gaps = 56/314 (17%)
Query: 1 MRVKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN 60
M +P V + A S P +PK+ P P P P P PP S F S
Sbjct: 878 MESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES--SLVFPPPPPSPV 935
Query: 61 PRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRP 120
P PPP P+ P + + + P + PTP + S +G + P
Sbjct: 936 PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKS---SSGAEHPEP 992
Query: 121 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPP-PGDLQYSFFSSPSLAN---- 175
+D + +++ + + + L P APP PG L S + P +
Sbjct: 993 KRPSVDSL--VSKFTPPAESGSPSKE----TLPPPAAPPKPGKLNLSGVNLPGVLQQGCV 1046
Query: 176 SIRSP----------EERATPHAKSERPSHPLYEPEPE----PRDSPQPGQGHSPGATA- 220
S ++P E +P + S+ P P PE E P + P G++ A
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPP---PETELPLPPIEIPAVFSGNTSPKVAV 1103
Query: 221 -----------AATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSP 269
+ PP P D + L A+I + T + P P
Sbjct: 1104 VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMAT-----------VVPQVP 1152
Query: 270 EPEPQLLDPQPRFL 283
L QP FL
Sbjct: 1153 TSPKSSLSVQPGFL 1166
Score = 34.7 bits (78), Expect = 0.76
Identities = 53/215 (24%), Positives = 75/215 (34%), Gaps = 19/215 (8%)
Query: 849 SSDLLDFALSASRPESRKA------SGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGS 902
SS + + S+S PES+ SG P + +Q +++ S K S
Sbjct: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES 590
Query: 903 SGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHP 962
S A + +P S PP +TP A++ P L PPP P P
Sbjct: 591 SKARMESMNRPYTSL---VPPLSPQPKIVTPYT----ASQPSPPLPPPPPPPPPPPPPPP 643
Query: 963 PANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAP 1022
P LP AG + K T N+ S A + P S +
Sbjct: 644 PPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILV 703
Query: 1023 PPTG------GPCLPPSKASFFSSSEGAPFSGSAP 1051
PP G P PP+ S + + AP + S P
Sbjct: 704 PPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLP 738
Score = 33.1 bits (74), Expect = 2.2
Identities = 61/237 (25%), Positives = 82/237 (34%), Gaps = 28/237 (11%)
Query: 870 TYAGPPTSA--LPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTF----PP 923
T A PPT +P + FP+ SP P P L +Q+F PP
Sbjct: 799 TQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPV------PVPPPTLPKQQSFCAKPPP 852
Query: 924 GRAASYGLTPAASDCRA-AETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFA 982
L+P S + A FP P P AM P PAN PQ + +
Sbjct: 853 SP-----LSPVPSVVKQIASQFPP-PPTPPAMESQPLKPVPANV-APQSPPAVKAKPKWQ 905
Query: 983 PTK-PFTGQDCANSK-DCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSS 1040
P+ P D + S + P PS + PPPT P S + +
Sbjct: 906 PSSIPVPSPDFPPPPPESSLVFP-----PPPPSPVPAPPPPPPPTASPTPDKSGSPGKKT 960
Query: 1041 SEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPE 1097
S+ + G P P +S S G P+ S S S + + S PS E
Sbjct: 961 SKTSSPGGKKPPPTP-QRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKE 1016
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 62.4 bits (150), Expect = 3e-09
Identities = 89/321 (27%), Positives = 111/321 (34%), Gaps = 63/321 (19%)
Query: 160 PGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGAT 219
P S ++P + + P R TP A P+HP +P+P+ + +P Q P
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRA----PAHPS-QPKPKGLQALRPPQVTPPRKD 291
Query: 220 AAATGLPPEPEPDSTDYSELA-------DADILSELASLTCPEAQLLEAQALEPPSPEPE 272
AA P P +T A +SLTC QL L PPSP
Sbjct: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC---QLATPLPLAPPSPSAP 348
Query: 273 PQLLD-PQPRFLDP-QALEPLGEA--------LELPPLQPLADP--LGLPGLALQALDTL 320
P L P P P QA LG L PPL PLA P P LAL L
Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP 408
Query: 321 PDSLESQLLDPQALDPLPKLLDVPGRRLEPQQP------LGHCPLAEPLRLDLCSPHGPP 374
P S L P A PQ P L P + P + +P PP
Sbjct: 409 PSPPASPPLSPLATP-------------SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455
Query: 375 GPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPP 434
A + P L A P ++ P P + ++ A PPP P
Sbjct: 456 ASPPVSPSATPPSQAPPSL-------------AAPPLQVPPSPPASPPMSPSATPPPQAP 502
Query: 435 P----PPPALPGPGPVSVPEL 451
P PP L P P + P L
Sbjct: 503 PPLAAPPLQLAKPPPQAPPAL 523
Score = 61.2 bits (147), Expect = 8e-09
Identities = 128/518 (24%), Positives = 164/518 (31%), Gaps = 120/518 (23%)
Query: 12 SSAVCSSPDYLREPKYYPGGPPTPRP--LLPTRPP-ASPP--DKAFSTHAFSENP--RPP 64
SS S P P+ P P P+P L RPP +PP D A + S +P P
Sbjct: 250 SSPARSGPSARGTPRA-PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 65 PRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQL 124
P ++ PP L P P ++ Q P P+ S S P +Q
Sbjct: 309 PSAALQSQAPPTL-----PATPHSSSLTCQLATPLPLAPPSPSAP----------PSLQT 353
Query: 125 IDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQ-----------YSFFSSPSL 173
L PPA PP +SF SP L
Sbjct: 354 ---------------------------LPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386
Query: 174 ANSIRSPEERATPHAKS---ERPSHPLYEPEPEPRDSPQPGQGHSPGATAA----ATGLP 226
+ + +P +A P + P P P P +P P +P A A A P
Sbjct: 387 S-PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP---QAPNALAVHLLQAPFSP 442
Query: 227 PEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQL---LDPQPRFL 283
P P +S A + + L PPSP P + P P+
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
Query: 284 DPQALEPLG---------EALELPPLQPL-ADPLGLPG---------LALQALDTLPDS- 323
P A PL AL PPLQ L + P PG L + L T P
Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562
Query: 324 ---LESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHP 380
L + LL P L P R P P ++ P +P PP P P
Sbjct: 563 PPVLAAPLLQVPPSPPASPTLQAPRR---PPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619
Query: 381 KYALRRTDRPKILCRRRKAGRG-RKADAGPEGRLLPLPMPTGLVAAL-----AEPPPPP- 433
L D R D+GPEG P P +AA + P PP
Sbjct: 620 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 679
Query: 434 --------PPPPPALPGPGPV----SVPELKPESSQTP 459
P P P GPG ++ E + S TP
Sbjct: 680 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717
Score = 58.5 bits (140), Expect = 5e-08
Identities = 112/446 (25%), Positives = 144/446 (32%), Gaps = 77/446 (17%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN---------PRPPPRRDPSTRRPPVLAK 79
PG P P P+ P A +E P PR P TR ++
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGP-TRSAGTSSR 88
Query: 80 GDDPLPPRAAR----PVSQARCPTPV---GDGSSSRRCWDNGRVNLR-PVVQLIDIMKDL 131
PP + R P ++ P PV G S + R G+ LR + + K
Sbjct: 89 NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148
Query: 132 TRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSE 191
+ +G D G P P P + S + + +P R P +
Sbjct: 149 EAPKRSALSAGARRDTSG---PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 205
Query: 192 RPS------HPLYEPEPEPRDSPQPGQG-HSPGATAAATGLPPEPEPDSTDYSELADADI 244
R S H EP P R P G G P + + ++ P P + S
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 245 LSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLA 304
+ + P+ + L QAL PP P PR AL PL + PLA
Sbjct: 266 PAHPSQ---PKPKGL--QALRPPQVTP--------PRKDAAPALGPLSSS-------PLA 305
Query: 305 DPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLR 364
P L QA TLP + S L Q PLP L P P A P
Sbjct: 306 TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLP---------LAPPSPS-----APPSL 351
Query: 365 LDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVA 424
L SP P P A P + P L PL P
Sbjct: 352 QTLPSPPATP-----PSQATTSLGSPTLQATHSFL---------PSPPLSPLATPPPQAP 397
Query: 425 -ALAEPPPPPPPPPPALPGPGPVSVP 449
ALA PP PP PPA P P++ P
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATP 423
Score = 50.8 bits (120), Expect = 1e-05
Identities = 71/277 (25%), Positives = 96/277 (34%), Gaps = 46/277 (16%)
Query: 19 PDYLREPKYYPGGPPTPRPLLP--TRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPV 76
P P P PP P+ P T PP +PP A + +PPP+ P+ PP+
Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA---KPPPQAPPALATPPL 528
Query: 77 LA--------KGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQL---- 124
A G P P A+ P+S P P V P++Q+
Sbjct: 529 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-----------VLAAPLLQVPPSP 577
Query: 125 -----IDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLA----N 175
+ + D SG L L L+ P PPP S S P LA +
Sbjct: 578 PASPTLQAPRRPPTPGPDTSVSGPRLT---LALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
Query: 176 SIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLP--PEPEPDS 233
+ +PEE + E + P+ E P A G P P P P +
Sbjct: 635 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 694
Query: 234 TDYSELADADILSELASLTCPEAQLLEAQALEP-PSP 269
T AD L + PE+ AL+P PSP
Sbjct: 695 TG---PGSADGLCTIYETEGPESATPAPGALDPGPSP 728
Score = 45.4 bits (106), Expect = 4e-04
Identities = 93/371 (25%), Positives = 119/371 (32%), Gaps = 49/371 (13%)
Query: 1253 ASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDL 1312
A S S R+ R P GRG A AK G + PL Q +
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
Query: 1313 GLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGA 1372
+ + P +S A G R D GP P TPS + +G
Sbjct: 137 SAEETVARGKATEAPKRS-ALSAGARR--DTSGP---TPGTPSP-AMARRSRAAGTEVGL 189
Query: 1373 PELDGKHFPPLAHPPTVFDAGLQKAYSPTC--SPTLGFKEELRPPPTKLAACEPLKHGLQ 1430
P P PPT G +K+ S S T R P P L
Sbjct: 190 PRPAPSARP---RPPT---EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 1431 GASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPP--------GSAARSPPYEGK 1482
++ ++ A++ S R P H P KG PP + A P
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 1483 VGTGLLADFLGRTEAACLSA-PH-------LASP-PATPKADKEPLEMARPPGPP-RGPA 1532
+ T + L L A PH LA+P P P + P + P PP P+
Sbjct: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
Query: 1533 AAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLG--------GGPKSG 1584
A G P L T S +P L PL PQA P L P S
Sbjct: 364 QATTSLGSPTL-QATHSFLPSPPLSPLATPP-------PQAPPALALPPLQAPPSPPASP 415
Query: 1585 FLGPMAEPHPE 1595
L P+A P P+
Sbjct: 416 PLSPLATPSPQ 426
Score = 42.7 bits (99), Expect = 0.003
Identities = 64/221 (28%), Positives = 84/221 (38%), Gaps = 28/221 (12%)
Query: 889 PSRGAKASPVAVGSSGAGADPSFQ--PVLSARQT-FPPGRAASYGLTPAASDCRAAETFP 945
P A SP A A P Q P L+A PP AS ++P+A+ A P
Sbjct: 446 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP--P 503
Query: 946 KLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSG 1005
L PP +A+ P PPA P Q++ +P F GQ +
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPL-------QALPSPPASFPGQ---------APFSPS 547
Query: 1006 NSLPASPSSAHSAGYAPPPTGGPCL--PPSKASFFSSSEGAPFSGSAPTPLRCDS--RAS 1061
SLP SP A APP P L PPS + S + AP P P S R +
Sbjct: 548 ASLPMSP-LATPPPQAPPVLAAPLLQVPPSPPA--SPTLQAPRRPPTPGPDTSVSGPRLT 604
Query: 1062 TVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQF 1102
G P + S+T + + SSS +PE R +
Sbjct: 605 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645
Score = 42.0 bits (97), Expect = 0.005
Identities = 164/709 (23%), Positives = 215/709 (30%), Gaps = 138/709 (19%)
Query: 934 AASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGA-GQSVFAPTKPFTG--- 989
AA+ AA L P P R P PA L G GA G+ A G
Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAA--LRVLGAAGAVGRKPLAERAGGIGGAT 69
Query: 990 -QDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPP----TGGPCLPPSKASFFSSSEGA 1044
+ A + + G+ + PAS A G PP + GP P +AS ++
Sbjct: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS--GTTRPG 127
Query: 1045 PFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQ----PSPENCR 1100
P LR S TV+ G K T A SA SA + +S PSP R
Sbjct: 128 PLGQKG---LRI-SAEETVARG-----KATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 178
Query: 1101 QFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVS 1160
+ A G ++ P + + + S ++ +
Sbjct: 179 RSRAAGT---EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 1161 ETFSES-SSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDW----------- 1208
S S SS +T + P G R A + Q L+ L
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
Query: 1209 -NEASSAPGYNWNQSVLFQSSSKPG-----RGRRKKVDLFEASHLGFPT-SASAAASGYP 1261
SS+P + S QS + P L L P+ SA + P
Sbjct: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP 355
Query: 1262 SKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLF----QDSPDLGLDYY 1317
S +T P Q G A F+P P P++PL Q P L L
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHS---------FLPSP-PLSPLATPPPQAPPALALPPL 405
Query: 1318 SGDSSMSPLPSQSRAFGVGERDPCDFI-----GPYSMNPSTPSDGTFGQGFHCDSPSLGA 1372
S P S + P P+S PS P F SP +
Sbjct: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF-------SPP-AS 457
Query: 1373 PELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGA 1432
P + PP PP++ LQ SP SP + PPP
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM--SPSATPPP---------------- 499
Query: 1433 SLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFL 1492
A L+ L L +P +P T PP A SPP A F
Sbjct: 500 ------QAPPPLAAPPLQLAKPPPQAPPALAT----PPLQALPSPP----------ASFP 539
Query: 1493 GRT----EAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTL 1548
G+ A+ +P PP P PL + PP PP P A
Sbjct: 540 GQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQA------------- 585
Query: 1549 SPVPRDSLLPLQDTAYRYP----GFMPQAHPGLGGGPKSGFLGPMAEPH 1593
PR P DT+ P P P P S GP H
Sbjct: 586 ---PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 631
Score = 41.6 bits (96), Expect = 0.006
Identities = 59/240 (24%), Positives = 84/240 (35%), Gaps = 22/240 (9%)
Query: 867 ASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRA 926
A+G P + G AT P +A P + + S P + PP +
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN 108
Query: 927 ASYGLTPAASDCRAAETFPK--------LVPPPSAMARSPTTHPPANTYLPQYGGYGAGQ 978
S G P +S RA+ T + +AR T P + L GA +
Sbjct: 109 TSPG--PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA----GARR 162
Query: 979 SVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFF 1038
PT A S A G+ LP SA PPT GP S AS
Sbjct: 163 DTSGPTPGTPSPAMARR---SRAAGTEVGLPRPAPSARPR----PPTEGPRKSVSSASEH 215
Query: 1039 SSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTA-SATSAASAASSSSSSFQPSPE 1097
S++E +P + P+ R ++ S P + A S SA + + QP P+
Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275
Score = 33.1 bits (74), Expect = 2.2
Identities = 80/347 (23%), Positives = 111/347 (31%), Gaps = 36/347 (10%)
Query: 735 TGKPKRKRRSRKNGTL--FPEQVPS--------GPGFGEAGA-EWAGDKGGGWAPHHGHP 783
T P RRSR GT P PS GP + A E + + A
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
Query: 784 GGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYFRSL 843
GG G Q +R+ +S+ + R + G P SQ +
Sbjct: 231 GG------GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
Query: 844 LD---SDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAV 900
+ D + L + S S A+ PPT LPA ++ + A+P+ +
Sbjct: 285 VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT--LPATPHSSSLTCQ--LATPLPL 340
Query: 901 GSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTT 960
A PS Q + S PP S T S A PP S +A P
Sbjct: 341 APPSPSAPPSLQTLPS-----PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 395
Query: 961 HPPANTYLPQYGGYGAGQSVFAPTKPFT--GQDCANSKDCSFAYGSGNSLPASPSSAHSA 1018
PPA P S P P N+ + P+ P A +
Sbjct: 396 APPALALPPLQAPPSPPAS--PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453
Query: 1019 GYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSP 1065
A PP PPS+A S AP P+P + + +P
Sbjct: 454 PPASPPVSPSATPPSQA---PPSLAAPPLQVPPSPPASPPMSPSATP 497
Score = 32.7 bits (73), Expect = 2.9
Identities = 52/241 (21%), Positives = 75/241 (31%), Gaps = 57/241 (23%)
Query: 404 KADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGP----GPVSVPELKPESSQT- 458
KA AG R P GL+ PP P PPPP P G KP + +
Sbjct: 7 KAKAGAAART-PAARAPGLLTP--RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
Query: 459 -------PVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGK---- 507
P + R G R A P + GR + ++ +S G+
Sbjct: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 508 -------ELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPG- 559
+ GLR+SAE T + + K PK L G
Sbjct: 124 TRPGPLGQKGLRISAEET-----------------------VARGKATEAPKRSALSAGA 160
Query: 560 -------KPKEPAVVAAEAATVAAATMAMPEVKKRRRRKQKLASPQPSYAADANDSKAEY 612
P P+ A + A + +P R + P+ S ++ + S E
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
Query: 613 S 613
S
Sbjct: 221 S 221
Score = 32.7 bits (73), Expect = 2.9
Identities = 66/255 (25%), Positives = 88/255 (34%), Gaps = 30/255 (11%)
Query: 860 SRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQ 919
S P S S + PP + P LA P + AK P A A A P Q + S
Sbjct: 484 SPPASPPMSPSATPPPQAPPP----LAAPPLQLAKPPPQA---PPALATPPLQALPSPPA 536
Query: 920 TFPPGRA-----ASYGLTPAASDCRAAETF---PKLVPPPSAMARSPTTHPPANTYLPQY 971
+FP G+A AS ++P A+ A P L PPS A SPT P P
Sbjct: 537 SFP-GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPPTPGP 594
Query: 972 GGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSA-----GYAPPPTG 1026
+G + P + S + SG L SSA S GY P G
Sbjct: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTL---SGPDLAGHSSSATSTPEELRGYDSGPEG 651
Query: 1027 GPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGT-----TASATSA 1081
G P + ++ A +S PL P G+ T T
Sbjct: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
Query: 1082 ASAASSSSSSFQPSP 1096
+A+ + + P P
Sbjct: 712 PESATPAPGALDPGP 726
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 61.6 bits (148), Expect = 6e-09
Identities = 93/323 (28%), Positives = 115/323 (35%), Gaps = 55/323 (17%)
Query: 154 RPPAPPPGDL--QYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPG 211
RPP PP + Q F S SL S R R + S +P+ + +P P P G
Sbjct: 766 RPPCPPGAESGPQTKFCSEISLIVSPR----RISVQLDSHQPTQSISQPPPPPSLLWSAG 821
Query: 212 QGHSPGATAAATGLPPEPEPDSTDYSELADADILSELAS---------LTCPEAQL-LEA 261
QG PG+ P ST++ + + S + L C E+ +
Sbjct: 822 QGQ-PGSQP--------PHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPG 872
Query: 262 QALEPPSPEPEPQLLDPQ-PRFLDPQALEPLGEALELPPLQPLAD-----PLGLPGLALQ 315
+ PP P P P + P P PQ G + PP PL P LPG +
Sbjct: 873 LGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL 932
Query: 316 ALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPL--GHCPLAEPLRLDLCSPHGP 373
L LP + + P P L PG + P PL PL PL P P
Sbjct: 933 PLPPLPGA---------GIPPPPPL---PGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPP 980
Query: 374 -PGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPP 432
PG P L P G G G +P P P L A PPPP
Sbjct: 981 LPGAGIPPPPPLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPP--LPGAGIPPPPP 1035
Query: 433 PP----PPPPALPGPGPVSVPEL 451
P PPPP LPG G P L
Sbjct: 1036 LPGAGIPPPPPLPGAGIPPPPPL 1058
Score = 50.1 bits (118), Expect = 2e-05
Identities = 106/457 (23%), Positives = 134/457 (29%), Gaps = 99/457 (21%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVL-AKGDDPLPPR 87
P PP P +PT P + P P PPP PP L G PLPP
Sbjct: 878 PPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL 937
Query: 88 AARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLD- 146
+ P P G++ + P L +G+ L
Sbjct: 938 PGAGIP----PPPPLPGAA-----------IPP--------------PPPLPGAGIPLPP 968
Query: 147 -CGGLRLSRPPA------PPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYE 199
G + PP PPP L + P P P A P P
Sbjct: 969 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP--PPLP 1026
Query: 200 PEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLL 259
P P PG G P G+PP P L P L
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-----------------LPGAGIPPPPPL 1069
Query: 260 EAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQP---LADPLGLPGLALQA 316
+ PP P P + P P G + PP P + P LPG +
Sbjct: 1070 PGAGIPPPPPLPGAGIPPPPPL---------PGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
Query: 317 LDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPG- 375
LP + + P P L PG + P PL + P L PP
Sbjct: 1121 PPPLPGA---------GIPPPPPL---PGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPL 1168
Query: 376 -----PEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPP 430
P P + P + G G G +P P P + P
Sbjct: 1169 PGAGIPPPPPLPGVGIPPPPPL------PGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA 1222
Query: 431 PPPPPP------PPALPGPGPVSVPELKPESSQTPVV 461
PP PPP PP LP GP +P++ + TP V
Sbjct: 1223 PPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259
Score = 44.7 bits (104), Expect = 7e-04
Identities = 92/366 (25%), Positives = 118/366 (32%), Gaps = 73/366 (19%)
Query: 152 LSRPPAPPPGDLQYSFFSSPSLA--NSIRSPEERATPHAKSERPSHPLYEPEPEP----- 204
+S+PP PPP L + P +SI + + + H+ S + P P P
Sbjct: 807 ISQPP-PPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTE 865
Query: 205 RDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQAL 264
S PG G P PP P P T + L S P+ L+ +
Sbjct: 866 SSSSMPGLGMVPP--------PPPPLPGMT----------VPTLPSTAIPQPPPLQGTEM 907
Query: 265 EPPSPEPEPQLLDPQPRFLDPQALEPL----GEALELPPLQP---LADPLGLPGLALQAL 317
PP P P P P P L + PL G + PP P + P LPG +
Sbjct: 908 LPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLP 967
Query: 318 DTLPDS-------LESQLLDPQALDP---LPKLLDVPGRRLEPQQPLGHCPLAEPLRLD- 366
LP + L + P P +P +PG + P PL + P L
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1027
Query: 367 --LCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLP--------- 415
+ P PG P L P G G G +P
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPP---PPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1084
Query: 416 LPMPTGLVAALAEPPPP---------PPP------PPPALPGPGPVSVPELKPESSQTPV 460
+P P L A PPPP PP PPP LPG G P L P
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1144
Query: 461 VSTRKG 466
R G
Sbjct: 1145 PLPRVG 1150
Score = 43.1 bits (100), Expect = 0.002
Identities = 80/328 (24%), Positives = 98/328 (29%), Gaps = 45/328 (13%)
Query: 149 GLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDS- 207
GL + PP PP + S ++ P P + P P P
Sbjct: 872 GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931
Query: 208 ----PQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQA 263
P PG G P +PP P A + L P L
Sbjct: 932 LPLPPLPGAGIPPPPPLPGAAIPPPPPLPG------AGIPLPPPLPGAGIPPPPPLPGAG 985
Query: 264 LEPPSPEPEPQLLDPQPRFLDPQALEPL----GEALELPPLQP---LADPLGLPGLALQA 316
+ PP P P + P P L + P G + PP P + P LPG +
Sbjct: 986 IPPPPPLPGAGIPPPPP--LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1043
Query: 317 LDTLPDS--LESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPP 374
LP + L + P P L PG + P PL + P L PP
Sbjct: 1044 PPPLPGAGIPPPPPLPGAGIPPPPPL---PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1100
Query: 375 GPEG-----HPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEP 429
G P P L G G G +P P P V
Sbjct: 1101 PLPGVGIPPPPPLPGAGIPPPPPL-----PGAGIPPPPPLPGAGIPPPPPLPRVGI---- 1151
Query: 430 PPPPPP------PPPALPGPGPVSVPEL 451
PPPPP PPP LPG G P L
Sbjct: 1152 PPPPPLPGAGIPPPPPLPGAGIPPPPPL 1179
Score = 32.3 bits (72), Expect = 3.8
Identities = 41/123 (33%), Positives = 48/123 (39%), Gaps = 26/123 (21%)
Query: 263 ALEPPSPEPEPQLLDPQPRF---LDPQALEPLGEALELPPLQPLADPLGLPGL--ALQAL 317
A EP +P P + PQP LD L P G A E P G P AL AL
Sbjct: 229 AEEPAAP---PTAVSPQPGAFLGLDRFLLGPSGGAGEAP---------GSPDTEQALSAL 276
Query: 318 DTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPE 377
LP+SL ++ +PQ P P L P P A+P D S P PE
Sbjct: 277 SDLPESLAAEPREPQQ-PPSPGGL--------PVSEAPSLPAAQPAAKDSPSSTAFPFPE 327
Query: 378 GHP 380
P
Sbjct: 328 AGP 330
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 61.2 bits (147), Expect = 8e-09
Identities = 119/490 (24%), Positives = 160/490 (32%), Gaps = 93/490 (18%)
Query: 19 PDYLREPKYYPGG--PPTPRPLLPTRPP-ASPPDKAFSTHAFSENPRPPPRRDPSTRRP- 74
P L P PG PP P + R P AS S + S +P P R P P
Sbjct: 595 PKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654
Query: 75 ---------PVLAKGDDPLP--PRAARPVSQARC-----PTPVGDGSSSRRCWDNGRVNL 118
P + P P PR+ P + A P PV +S + + L
Sbjct: 655 GDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTL 714
Query: 119 RPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIR 178
P+ + I KD S PP+PPP S+ P +
Sbjct: 715 TPLQESPVISKDQ---------------------SPPPSPPP-----SYHPPPP---PTK 745
Query: 179 SPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSE 238
PE + SE PL +P P P P + + A PPE S E
Sbjct: 746 KPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQD----LSMADFPPPEEAFFSVASPE 801
Query: 239 LADADILSELASLTCPEAQLLEAQALEPP-SPEPEPQLLDPQPRFLDPQALEPLGEALEL 297
A EL S + A ++PP SP+P P P P P + L + +
Sbjct: 802 PAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPV 861
Query: 298 -------PPLQPLADPLGLPGLA----LQALDTLPDSLESQLLDPQALD-PLPKLLD--- 342
PP + + PL P L L+++ P + L P A PL + L
Sbjct: 862 GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGA-PGGAPTPALGPSAPQKPLRRALSGRA 920
Query: 343 ----VPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRT------DRPKI 392
P L L C LA L P+GPP E P + T +
Sbjct: 921 SPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRK 980
Query: 393 LCRRRKAGRGRKADAG----PEGRLLPLPMPTGLVAALAEPPPP---------PPPPPPA 439
L R +AD E R + P + PPP PPP P+
Sbjct: 981 LQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPS 1040
Query: 440 LPGPGPVSVP 449
P P++ P
Sbjct: 1041 YPRAEPLTAP 1050
Score = 49.7 bits (117), Expect = 2e-05
Identities = 97/427 (22%), Positives = 141/427 (33%), Gaps = 93/427 (21%)
Query: 59 ENPRPPPRRDPSTRRPPVLAKGDDPL--PPRAARPVSQARCPTPV----GDGSSSRRCWD 112
+ P PPPRR S + LA D PL PP+ R Q + P P +G+ + C
Sbjct: 495 KRPPPPPRRTHSLHQRG-LAVPDGPLGLPPKPERK-QQPQLPRPPTTGGSEGAGAAPCPP 552
Query: 113 NGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLR------LSRPPAPP------- 159
N + P + + + L S + G L+ PPA P
Sbjct: 553 NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPK 612
Query: 160 ---------PGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRD--SP 208
PG S +S ++S +P +R+ P + + P P+ SP
Sbjct: 613 PERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSP 672
Query: 209 QPGQGHSPGATAAATGLPPE-PEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPP 267
P + SP A A P P P ST +A PP
Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGPVSTT------------------------DASPQSPP 708
Query: 268 SPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQ 327
+P+ L P Q+ P P P P P + ++A + ++ E
Sbjct: 709 TPQTTLTPLQESPVISKDQSPPPSPP----PSYHPPPPPTKKPEVVVEA-PSASETAEEP 763
Query: 328 LLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRT 387
L DP P P + E + P E + SP P GP G P+
Sbjct: 764 LQDPNWPPPPPPAPE------EQDLSMADFPPPEEAFFSVASPE-PAGPSGSPELV---- 812
Query: 388 DRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVS 447
A + L + P +PPP PP P PA PG V+
Sbjct: 813 --------------SSPAASSSSATALQIQPPGS-----PDPPPAPPAPAPASSAPGHVA 853
Query: 448 -VPELKP 453
+P+ +P
Sbjct: 854 KLPQKEP 860
Score = 45.8 bits (107), Expect = 3e-04
Identities = 75/311 (24%), Positives = 100/311 (32%), Gaps = 61/311 (19%)
Query: 170 SPSLANSIRSPEERATPHAKSER----PSHPL-YEPEPEPRDSPQPGQGHSPGATAAATG 224
S SL R P H+ +R P PL P+PE + PQ + + G + A
Sbjct: 488 SVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGA 547
Query: 225 LPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLD 284
P P P ++ L+ S PE L + S P L
Sbjct: 548 APCPPNPANSWVPGLSPGGSRRPPRS---PERTLSPSSGYSSQSGTPT----------LP 594
Query: 285 PQALE--PLGEALELPPLQPLADPLGLPGLALQA-----LDTLPDSLESQLLDPQALDPL 337
P+ L P PP L PG ++ + + D S PQ L PL
Sbjct: 595 PKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL 654
Query: 338 PKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRR 397
+P P+ P P PP P A P ++
Sbjct: 655 GDRFVIPPH---PKVPAPFSP--------------PPSKPRSPNPAAPALAAPAVV---- 693
Query: 398 KAGRGRKADAGPEGRLLPLPMPTGLVAALAEPP-------PPPPPPPPALPGPGPVSVPE 450
G DA P+ P P + L E P PPP PPP P P P PE
Sbjct: 694 -PGPVSTTDASPQSP----PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPE 748
Query: 451 L---KPESSQT 458
+ P +S+T
Sbjct: 749 VVVEAPSASET 759
Score = 44.3 bits (103), Expect = 0.001
Identities = 73/289 (25%), Positives = 108/289 (37%), Gaps = 38/289 (13%)
Query: 814 GSYYSTGAPSGQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAG 873
G + S +P ++ + ++ S D S L S +PES AS +
Sbjct: 394 GRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVP 453
Query: 874 PPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASY---G 930
PP + RG + S + +++ SSG + S R PP R S G
Sbjct: 454 PPQGG--SGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRG 511
Query: 931 LTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQ 990
L A P +PP + P P T G GAG AP P
Sbjct: 512 L--------AVPDGPLGLPPKPERKQQPQLPRPPTT----GGSEGAGA---APCPP---- 552
Query: 991 DCANSKDCSFAYGSGNSLPASP--SSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFSG 1048
+ ANS + G P SP + + S+GY+ +G P LPP + G P S
Sbjct: 553 NPANSWVPGLSPGGSRRPPRSPERTLSPSSGYS-SQSGTPTLPPKGLA------GPPASP 605
Query: 1049 SAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPE 1097
P + + S SPG ++S TS S++S + S + P+
Sbjct: 606 GKAQPPKPERVTSLRSPGA-----SVSSSLTSLCSSSSDPAPSDRSGPQ 649
Score = 40.8 bits (94), Expect = 0.011
Identities = 61/255 (23%), Positives = 80/255 (31%), Gaps = 30/255 (11%)
Query: 875 PTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASYGLT-- 932
P+S +Q G T P +G P S G P + V S R PG + S LT
Sbjct: 580 PSSGYSSQSGTPTLPPKGLAGPP---ASPGKAQPPKPERVTSLRS---PGASVSSSLTSL 633
Query: 933 ------PAASDCRAAETFPKL----VPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVF- 981
PA SD + L V PP +P + PP+ P
Sbjct: 634 CSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVV 693
Query: 982 ---------APTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPP 1032
+P P T Q S S P SP ++ PPPT P +
Sbjct: 694 PGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP--PPPPTKKPEVVV 751
Query: 1033 SKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSF 1092
S ++E + P P +S + P+ S S A S S
Sbjct: 752 EAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPEL 811
Query: 1093 QPSPENCRQFAGASQ 1107
SP A A Q
Sbjct: 812 VSSPAASSSSATALQ 826
Score = 36.6 bits (83), Expect = 0.20
Identities = 81/341 (23%), Positives = 109/341 (31%), Gaps = 70/341 (20%)
Query: 4 KPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRP 63
KP+ +V SA ++ + L++P + P PP P + PP++AF + A S P
Sbjct: 746 KPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVA-SPEPAG 804
Query: 64 PPRRDPSTRRPPVLAKGDDPL---PPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRP 120
P P + L PP + P P P G V P
Sbjct: 805 PSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAP--------GHVAKLP 856
Query: 121 VVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIR-- 178
Q V GG PP D+ +PSL +R
Sbjct: 857 ------------------QKEPVGCSKGG-------GPPREDVGAPLV-TPSLLQMVRLR 890
Query: 179 ---SPEERATPHAKSERPSHPL-------YEPEPEPRDSPQPGQGHSPGATAAATGL--- 225
+P TP P PL P P P + AA+ GL
Sbjct: 891 SVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSA 950
Query: 226 ----PPEPEPDSTDYSELADADILS------ELASLTCPEAQL-----LEAQALEPPSPE 270
PPE EP + I S +L PE Q L A+ L S +
Sbjct: 951 QPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAE-LRSISEQ 1009
Query: 271 PEPQLLDPQPRFLDPQALEP-LGEALELPPLQPLADPLGLP 310
PQ P+ P A +P +G P P A+PL P
Sbjct: 1010 RPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAP 1050
Score = 35.4 bits (80), Expect = 0.45
Identities = 80/340 (23%), Positives = 111/340 (32%), Gaps = 81/340 (23%)
Query: 175 NSIRSPEERAT-PHAKSERPSHPLYEPEPEPRDSPQPGQGHSPG---ATAAATGLPPEPE 230
+S+ SP+ R+ P + S+ SH S +G S G ++ A+ + P P+
Sbjct: 397 SSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQ 456
Query: 231 PDSTDYS----ELADADILSELASLTCPEAQLLEAQALEPPSPEPE-------------- 272
S S A+A + S + + + L+ P P P
Sbjct: 457 GGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPD 516
Query: 273 -PQLLDPQP-RFLDPQALEPL----GEALELPPLQPLADPLGLPGLALQALDTLPDSLES 326
P L P+P R PQ P E P P +PGL+ P S E
Sbjct: 517 GPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPER 576
Query: 327 QL--------------LDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEP------LRLD 366
L L P+ L P PG+ +P +P L P
Sbjct: 577 TLSPSSGYSSQSGTPTLPPKGLAGPPAS---PGKA-QPPKPERVTSLRSPGASVSSSLTS 632
Query: 367 LCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAAL 426
LCS P P P+IL P G +P + A
Sbjct: 633 LCSSSSDPAPSDR--------SGPQILT--------------PLGDRFVIPPHPKVPAPF 670
Query: 427 AEPPPPPPPPPPALPG-------PGPVSVPELKPESSQTP 459
+ PP P P PA P PGPVS + P+S TP
Sbjct: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTP 710
Score = 33.5 bits (75), Expect = 1.7
Identities = 75/316 (23%), Positives = 109/316 (34%), Gaps = 64/316 (20%)
Query: 1250 PTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDS 1309
P + +SGY S+ T P+G G A K + PKP+ V L
Sbjct: 574 PERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQP----------PKPERVTSLRSPG 623
Query: 1310 PDLGLDYYSGDSSMS-PLPSQSRAFGV----GER---DPCDFI-GPYSMNPSTPSDGTFG 1360
+ S SS S P PS + G+R P + P+S PS P
Sbjct: 624 ASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPR----- 678
Query: 1361 QGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTC-------SPTLGFKEELR 1413
SP+ AP L P P + DA Q +P SP + ++
Sbjct: 679 ------SPNPAAPALAAPAVVP--GPVSTTDASPQSPPTPQTTLTPLQESPVIS--KDQS 728
Query: 1414 PPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPG-- 1471
PPP+ + P + + A + + + + PL P++ P PP
Sbjct: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETA--EEPLQDPNWPPPP--------PPAPE 778
Query: 1472 ----SAARSPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARP--P 1525
S A PP E + + G + +P L S PA + L++ P P
Sbjct: 779 EQDLSMADFPPPEEAFFSVASPEPAGPS-----GSPELVSSPAASSSSATALQIQPPGSP 833
Query: 1526 GPPRGPAAAAAGYGCP 1541
PP P A A P
Sbjct: 834 DPPPAPPAPAPASSAP 849
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 60.8 bits (146), Expect = 1e-08
Identities = 105/401 (26%), Positives = 143/401 (35%), Gaps = 81/401 (20%)
Query: 22 LREPKYYPGGPPTPRPLLP--TRPP---ASPPDKAFSTHAFSENPRPPPRRDPSTRRPPV 76
L P P P P PL P T PP PP S P PP + + PPV
Sbjct: 401 LPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPV 460
Query: 77 L------AKGDDPLPP--RAARPVSQA-----RCPTPVGDGSSSRRCWDNGRVNLRPVVQ 123
+ +G PL P RA R ++A PTP ++ D+ V +
Sbjct: 461 VPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTF 520
Query: 124 LIDIMKDL-----TRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIR 178
L +I + + R S+ ++ +D PP PP ++ S P + S
Sbjct: 521 LKNIRQFIMPVVSARSSRVIKTPRRFMD------EDPPKPP--KVEVSPVLRPPITTSPP 572
Query: 179 SPEERA---TPHAKSERPSHPLYEPE--------------------PEPRDSPQPGQGHS 215
P+E A +P PS P+ PE P P +P P S
Sbjct: 573 VPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPS 632
Query: 216 PGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQL 275
P PP P S L A L E+ L P +PEPEP
Sbjct: 633 P---------PPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPP 683
Query: 276 LDPQPRFLDPQALEPLGEALELP--------PLQPLADPLGLPGLALQALDTLPDSLESQ 327
D P +P+A+ L LP P++ P G P AL P + ++Q
Sbjct: 684 ADDSPAEPEPRAVGRTNH-LSLPRFAPVVTTPVKAEVSPHGAP-----ALSNGPQT-QAQ 736
Query: 328 LLDP-QALDP--LPKLLDVPGRRLEPQQPLGHCPLAEPLRL 365
LL P QAL LP+ L P +L+P P E R+
Sbjct: 737 LLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARI 777
Score = 45.1 bits (105), Expect = 6e-04
Identities = 116/495 (23%), Positives = 162/495 (32%), Gaps = 120/495 (24%)
Query: 32 PPTPRPLLPTR---PPASPPDKAFSTHAFSENPRPPPRRDPS-TRRPPVLAKGDDPLPPR 87
PP PR R P SP + +F P P P S T P + D P PPR
Sbjct: 1854 PPAPRSFSGARIKVPNYSPSRRPLGGVSFG--PLPSPGSPSSLTHHIPTVGDPDFPAPPR 1911
Query: 88 AARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQL---IDIMKDLTRLSQDLQHSGVH 144
++R P+P+ R W + + P +++ ++ LT S +L G
Sbjct: 1912 ------RSRRPSPLAPRPPPSR-WASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPG-- 1962
Query: 145 LDCGGLRLSRPPAPPPGDLQYSF--------FSSPSL--ANSI--RSPEERATPHAKSER 192
P PPP DL F S+ L A S+ P + A +
Sbjct: 1963 --------PAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMG 2014
Query: 193 PSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLT 252
SH E SP H P +A GL P P + +L D
Sbjct: 2015 SSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVD--------- 2065
Query: 253 CPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGL 312
+ EA+A++ P + P P G P A LG G
Sbjct: 2066 --DGTDSEAEAVQQPRGQGTP----------------PSG------PGVVRAGVLGAAGD 2101
Query: 313 ALQALDTLPDSLESQLLD-------------PQALDPLPKLLDVPGRRLEPQQPLGHCPL 359
+ + LP + +L ++L P P L +P Q L P
Sbjct: 2102 RARPPEDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPL----ANGSQPSQGLTASP- 2156
Query: 360 AEPLRLDLCSPHGP--------PGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEG 411
A+P R P P P PE PK A + L + G P
Sbjct: 2157 ADPTRTFAWLPGAPGVRVLSLGPAPE-PPKPATSKIILVNKLGQVFVKMAGEGEPVPPPV 2215
Query: 412 RLLPLP------------MPTG-------LVAALAEPPPPPPPPPPALPGPGPVSVPELK 452
+ PLP +P G +V + PPPPPPP + GP S P
Sbjct: 2216 KQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPR-- 2273
Query: 453 PESSQTPVVSTRKGK 467
++ + VST G+
Sbjct: 2274 -QAIRVKRVSTFSGR 2287
Score = 43.5 bits (101), Expect = 0.002
Identities = 48/190 (25%), Positives = 70/190 (36%), Gaps = 20/190 (10%)
Query: 415 PLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRM 474
PLP P+ PPPPPP PP LP P P E + E S PVV + RG +
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQE-EQEESPPPVVPATCSRKRGRPPL 474
Query: 475 VVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVF 534
+ + T + S+ + E V+ + T LK N R ++
Sbjct: 475 TPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFLK---NIRQFIMPV 531
Query: 535 PPGEMPIILKRKR-------GRPPK---------NLLLGPGKPKEPAVVAAEAATVAAAT 578
++K R +PPK + P P+EPA V + +
Sbjct: 532 VSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPS 591
Query: 579 MAMPEVKKRR 588
+P +KRR
Sbjct: 592 TPVPLPEKRR 601
Score = 42.4 bits (98), Expect = 0.004
Identities = 105/456 (23%), Positives = 144/456 (31%), Gaps = 119/456 (26%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRA 88
P PP P P P PP++ P P PPP P PP+ P PP
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPPPPLC-------PPPPPPVSP----PPL------PSPPPP 447
Query: 89 ARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCG 148
Q P PV + SR+ GR L P SQ +
Sbjct: 448 PAQEEQEESPPPVVPATCSRK---RGRPPLTP--------------SQRAEREAARAGPE 490
Query: 149 GLRLSRPPAPPP-----GDLQYSFFSSPSLANSIRSPEERATP--HAKSER--------- 192
G + PP P P G + S +P +++ + P A+S R
Sbjct: 491 G---TSPPTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFM 547
Query: 193 ----PSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYS--ELADADILS 246
P P E P R P P A P P P ST E + +
Sbjct: 548 DEDPPKPPKVEVSPVLRP-PITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILRE 606
Query: 247 ELASLTCPEAQLLEAQALEPPSPEPEPQ----------LLDPQPRFLDPQALEPLGEALE 296
T +L PP P P P LL P+F +A + E++
Sbjct: 607 PTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVL 666
Query: 297 LPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGH 356
PP PLG P P+ E D +P P+ + GR P
Sbjct: 667 TPP------PLGAP--------EAPEP-EPPPADDSPAEPEPRAV---GRTNHLSLPRFA 708
Query: 357 CPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPL 416
+ P++ ++ SPHG P P+ + + L + +LLP
Sbjct: 709 PVVTTPVKAEV-SPHGAPALSNGPQTQAQLLQPLQAL----------------QTQLLPQ 751
Query: 417 PMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELK 452
+P PP P PP P P +P L+
Sbjct: 752 ALP----------PPQPQLQPP----PSPQQMPPLE 773
Score = 38.9 bits (89), Expect = 0.040
Identities = 67/286 (23%), Positives = 91/286 (31%), Gaps = 45/286 (15%)
Query: 180 PEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSEL 239
P TP A S P P P P SP P P + LP P P + + E
Sbjct: 402 PPPPLTPPAPSPPP------PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEE 455
Query: 240 ADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPP 299
+ ++ S L +Q E + P+ P P
Sbjct: 456 SPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT---------------PTPS 500
Query: 300 LQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPL 359
P P +A ++ L + Q + P +++ P R ++ P
Sbjct: 501 TATGGPPEDSPTVAPKSTTFLKNI--RQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVE 558
Query: 360 AEP-LRLDLC-SPHGP--PGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLP 415
P LR + SP P P P P A P L PE R
Sbjct: 559 VSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPL---------------PEKRRSI 603
Query: 416 LPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVV 461
L PT +L PPPPP PP P P P P SS+ P++
Sbjct: 604 LREPTFRWTSLTRELPPPPPAPPPPPAPSP---PPAPATSSRRPLL 646
Score = 37.4 bits (85), Expect = 0.12
Identities = 73/288 (25%), Positives = 101/288 (35%), Gaps = 42/288 (14%)
Query: 205 RDSPQ----PGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSE--LASLTCPEAQL 258
+D PQ GQG SP L E E + + + + E +A P A+
Sbjct: 337 QDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEK 396
Query: 259 LEAQA----LEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLAL 314
EA+ L PP+P P P L P P P L P PP P P P
Sbjct: 397 EEAKLPPPPLTPPAPSPPPPL--PPPSTSPPPPLCPPPPPPVSPPPLPSPPP---PPAQE 451
Query: 315 QALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQ----PLGHCPLAEPLRLDLCSP 370
+ ++ P + + + PL P +R E + P G P P +
Sbjct: 452 EQEESPPPVVPATCSRKRGRPPL-----TPSQRAEREAARAGPEGTSP---PTPTPSTAT 503
Query: 371 HGPP--GPEGHPKYA-----LRRTDRPKILCRRRKAGRG--RKADAGPEGRLLPLPMPTG 421
GPP P PK +R+ P + R + + R D P P P P
Sbjct: 504 GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDP-----PKP-PKV 557
Query: 422 LVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCR 469
V+ + PP PP P P P P P S+ P+ R+ R
Sbjct: 558 EVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
Score = 37.0 bits (84), Expect = 0.15
Identities = 55/242 (22%), Positives = 71/242 (29%), Gaps = 72/242 (29%)
Query: 9 VVTSSAVCSSPDYLREPKYYPGGPPTPRPL---------------------LPTRPPASP 47
+ TS V P + P P P TP PL LP PPA P
Sbjct: 567 ITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPP 626
Query: 48 PDKAFSTHAFSENPRPPPRRDPSTRRP-----PVLAKGDDPL--------PPRAARPVSQ 94
P A P PPP S+RRP P + L PP P +
Sbjct: 627 PPPA---------PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAP 677
Query: 95 ARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSR 154
P P D + GR N HL L
Sbjct: 678 EPEPPPADDSPAEPEPRAVGRTN--------------------------HL---SLPRFA 708
Query: 155 PPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGH 214
P P + S +P+L+N ++ + P + P P P+P+ P P
Sbjct: 709 PVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQ 768
Query: 215 SP 216
P
Sbjct: 769 MP 770
Score = 36.2 bits (82), Expect = 0.26
Identities = 76/314 (24%), Positives = 102/314 (32%), Gaps = 48/314 (15%)
Query: 156 PAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPG-QGH 214
P+PPP Q SP P AT K RP PL + R++ + G +G
Sbjct: 442 PSPPPPPAQEEQEESPP-------PVVPATCSRKRGRP--PLTPSQRAEREAARAGPEGT 492
Query: 215 SPGAT--AAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPE 272
SP + ATG PPE P S L + P ++ ++ P +
Sbjct: 493 SPPTPTPSTATGGPPEDSPTVAPKS----TTFLKNIRQFIMPVVSARSSRVIKTPRRFMD 548
Query: 273 PQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDT---LPDSLESQLL 329
P + P P+ + PP+ P+ P A T LP+ S L
Sbjct: 549 EDPPKPPKVEVSPVLRPPITTS---PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILR 605
Query: 330 DPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDR 389
+P R L P P +P PP P P A + R
Sbjct: 606 EPTFR------WTSLTRELPPPPP---------------APPPPPAPSPPPAPAT--SSR 642
Query: 390 PKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVP 449
+L R + E L P P+ EP PPP PA P P V
Sbjct: 643 RPLLLRAPQFTPSEAHLKIYESVLTPPPLGA---PEAPEPEPPPADDSPAEPEPRAVGRT 699
Query: 450 ELKPESSQTPVVST 463
PVV+T
Sbjct: 700 NHLSLPRFAPVVTT 713
Score = 35.4 bits (80), Expect = 0.45
Identities = 24/81 (29%), Positives = 34/81 (41%), Gaps = 5/81 (6%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAF-----STHAFSENPRPPPRRDPSTRRPPVLAKGDDP 83
P PP P L+ + PASPP +A ST + P PPP + P ++
Sbjct: 2253 PPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQ 2312
Query: 84 LPPRAARPVSQARCPTPVGDG 104
+P + S+ R TP G
Sbjct: 2313 VPGLGSGGFSRVRMKTPTVRG 2333
Score = 35.0 bits (79), Expect = 0.58
Identities = 58/198 (29%), Positives = 72/198 (36%), Gaps = 51/198 (25%)
Query: 267 PSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLES 326
P+P EP + P LD L P G P+Q L PL PDS +
Sbjct: 1808 PAPSSEPPGGEDPP--LDTDVLVP-GAPERHSPIQNLDPPLR------------PDSGSA 1852
Query: 327 QLLDPQALDPLPKLLDVPGRRLE------PQQPLGHC---PLAEPLRLDLCSPHGPPGPE 377
P P G R++ ++PLG PL P + H P
Sbjct: 1853 ---------PPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPT--V 1901
Query: 378 GHPKYAL--RRTDRPKILCRRRKAGRGRKADAGPEGRLLP---LPMPTGLVAAL------ 426
G P + RR+ RP L R R A P + P +P PT +V AL
Sbjct: 1902 GDPDFPAPPRRSRRPSPLAPRPPPSRW----ASPPLKTSPQLRVPPPTSVVTALTPTSGE 1957
Query: 427 -AEPPPPPPPPPPALPGP 443
A P P P PPPP GP
Sbjct: 1958 LAPPGPAPSPPPPEDLGP 1975
Score = 32.0 bits (71), Expect = 4.9
Identities = 20/57 (35%), Positives = 25/57 (43%), Gaps = 6/57 (10%)
Query: 1255 AAASGYPSKRSTGPRQPRGGRG------GGACSAKKERGGAAAKAKFIPKPQPVNPL 1305
A A P R+ P PR RG G C K++ A A IPKP+P P+
Sbjct: 200 AQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPV 256
Score = 31.6 bits (70), Expect = 6.5
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 14/87 (16%)
Query: 19 PDYLREPKYYPGGPPT--------PRPLLPTRP------PASPPDKAFSTHAFSENPRPP 64
P +++P P PT P PLL P PA PP T S P P
Sbjct: 2212 PPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASP 2271
Query: 65 PRRDPSTRRPPVLAKGDDPLPPRAARP 91
PR+ +R + P PP P
Sbjct: 2272 PRQAIRVKRVSTFSGRSPPAPPPYKAP 2298
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 60.1 bits (144), Expect = 2e-08
Identities = 90/355 (25%), Positives = 124/355 (34%), Gaps = 84/355 (23%)
Query: 146 DCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPH------------------ 187
D G R S A P G L S+ + SP+ R P
Sbjct: 325 DAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWE 384
Query: 188 ---AKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADI 244
+++ P PL+ P P+ PQP P+P+P S
Sbjct: 385 HGASRAMLPGSPLFTRAPPPKLQPQP---------------QPQPQPQSQ---------- 419
Query: 245 LSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPP--LQP 302
P+ QL PP P+ +PQ P P+ Q P+ E PP L+P
Sbjct: 420 ---------PQPQL-------PPQPQTQPQTPTPAPQH-PQQTWPPVNEGPPKPPTELEP 462
Query: 303 LADPLGLPGLALQALDTLPDSLESQLLDPQALDPL--PKLLDVPGRRLEPQQPLGHCPLA 360
+ GL L+A D + + ++ L P L P P+ VP E + L P
Sbjct: 463 EPEIEGLLTPVLEAGD-VDEGPVARPLSPTRLQPALPPEAQSVPELE-EVARVLAEIPRP 520
Query: 361 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKI--LCRRRKAGRGRKADAGPEGRLLPLPM 418
R + E P AL T + + + R G GPE L P+
Sbjct: 521 LKRRGSM---------EQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITE 571
Query: 419 PTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRR 473
+ A P PP P PPPA P S PE +P+S + V + G R RR
Sbjct: 572 GSEARAGPPAPAPPAPIPPPA---PSQSSPPE-QPQSMEMRSVLRKAGSPRKARR 622
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 60.1 bits (144), Expect = 2e-08
Identities = 90/355 (25%), Positives = 124/355 (34%), Gaps = 84/355 (23%)
Query: 146 DCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPH------------------ 187
D G R S A P G L S+ + SP+ R P
Sbjct: 325 DAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQPRGAPRQRPIPLSMIFKLQNAFWE 384
Query: 188 ---AKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADI 244
+++ P PL+ P P+ PQP P+P+P S
Sbjct: 385 HGASRAMLPGSPLFTRAPPPKLQPQP---------------QPQPQPQSQ---------- 419
Query: 245 LSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPP--LQP 302
P+ QL PP P+ +PQ P P+ Q P+ E PP L+P
Sbjct: 420 ---------PQPQL-------PPQPQTQPQTPTPAPQH-PQQTWPPVNEGPPKPPTELEP 462
Query: 303 LADPLGLPGLALQALDTLPDSLESQLLDPQALDPL--PKLLDVPGRRLEPQQPLGHCPLA 360
+ GL L+A D + + ++ L P L P P+ VP E + L P
Sbjct: 463 EPEIEGLLTPVLEAGD-VDEGPVARPLSPTRLQPALPPEAQSVPELE-EVARVLAEIPRP 520
Query: 361 EPLRLDLCSPHGPPGPEGHPKYALRRTDRPKI--LCRRRKAGRGRKADAGPEGRLLPLPM 418
R + E P AL T + + + R G GPE L P+
Sbjct: 521 LKRRGSM---------EQAPAVALPPTHKKQYQQIISRLFHRHGGPGPGGPEPELSPITE 571
Query: 419 PTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRR 473
+ A P PP P PPPA P S PE +P+S + V + G R RR
Sbjct: 572 GSEARAGPPAPAPPAPIPPPA---PSQSSPPE-QPQSMEMRSVLRKAGSPRKARR 622
>gi|153792012 DNA polymerase zeta [Homo sapiens]
Length = 3130
Score = 60.1 bits (144), Expect = 2e-08
Identities = 25/60 (41%), Positives = 38/60 (63%)
Query: 586 KRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEPES 645
+++R L+ P PSY A+ D YSDV++KL FL+ +S SPPRCW+P++P +
Sbjct: 1077 RKKRSHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSPINSSPPRCWSPTDPRA 1136
Score = 38.5 bits (88), Expect = 0.053
Identities = 57/234 (24%), Positives = 98/234 (41%), Gaps = 40/234 (17%)
Query: 1142 ILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSL 1201
ILD+SN+ P++VK + ++SE S++ + S N R ++ ++ EGQS L+ L
Sbjct: 1480 ILDMSNFKPERVKPR-SLSEAISQTKALSQCKN--------RNVSTPSAFGEGQSGLAVL 1530
Query: 1202 EKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGYP 1261
++L+ A N Q L + +P + ++ +A+
Sbjct: 1531 KELLQ--KRQQKAQNANTTQDPL-SNKHQPNKNISGSLEHNKANK--------------R 1573
Query: 1262 SKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFI---PKPQPVNPLFQDSP----DLGL 1314
++ T PR+PR R + +KE+ K + Q N + DSP D G
Sbjct: 1574 TRSVTSPRKPRTPRS----TKQKEKIPKLLKVDSLNLQNSSQLDNSVSDDSPIFFSDPGF 1629
Query: 1315 D-YYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDS 1367
+ YS + S+S P + F + F YS + P+D Q F D+
Sbjct: 1630 ESCYSLEDSLS--PEHNYNFDINTIGQTGFCSFYSGSQFVPADQNLPQKFLSDA 1681
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 59.7 bits (143), Expect = 2e-08
Identities = 135/591 (22%), Positives = 187/591 (31%), Gaps = 115/591 (19%)
Query: 29 PGGPPTPRPLLPTRP---PASPPDKAFSTHAFSENPRPP-----PRRDPSTRRPPVL-AK 79
P G PTP P P P +PP K T P P P PS++ P +
Sbjct: 1306 PKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSS 1365
Query: 80 GDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQ 139
+ P PP A TP G V+ L T ++++
Sbjct: 1366 KEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTRE-- 1423
Query: 140 HSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYE 199
G S+ PP S +P+ + P ATP +K + P+ P
Sbjct: 1424 --------GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP---ATPSSKGD-PTLPAVT 1471
Query: 200 PEPEPRDSPQPGQ---GHSP---GATAAATGLPPEP------------EPDSTDYSELAD 241
P P P++ P P Q SP AT A G P P P S
Sbjct: 1472 P-PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530
Query: 242 ADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQ 301
A +LS+ T + L A+ PSP+ P + P+ P + E PP
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKE-----ASSPPAV 1585
Query: 302 PLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAE 361
+ G P S + L+ P P PK P P G A
Sbjct: 1586 TPSTYKGAP------------SPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPA- 1632
Query: 362 PLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRR----RKAGRGRKADAGP----EGRL 413
P P P + P T + C+ +A +G A GP E +
Sbjct: 1633 PKGTPTSPPVTPSSLKDSP------TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLV 1686
Query: 414 LPLPMPTGLVAA-----------LAEPPPPPPPPPPALPGPGPVSVPELKP------ESS 456
P P T ++ A A PP P P GP+S P +SS
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSS 1746
Query: 457 QTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAE 516
+T +G A P++ K K S S VSA
Sbjct: 1747 KTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESAS-------------VSAA 1793
Query: 517 PTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRP--PKNLLLGPGKPKEPA 565
P+P V + P +P + +++ P P +L P KP PA
Sbjct: 1794 PSP---------PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPA 1835
Score = 56.6 bits (135), Expect = 2e-07
Identities = 64/233 (27%), Positives = 80/233 (34%), Gaps = 14/233 (6%)
Query: 874 PPTSALPAQRG--LATFPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASYGL 931
PP P+ +G AT +GA P A S G+ P+ P+ T P S
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS-PAATPLPKGAPTTPAATLPSPKG 1069
Query: 932 TPAASDCRAAETFPKLVPP-----PSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKP 986
PA + A T P PP P+ + PPA T GG APT P
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129
Query: 987 -FTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAP 1045
T G+ + A+P S PPP G P P + P
Sbjct: 1130 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1189
Query: 1046 FSGSAPTPLRCDSRASTVSP-GGYMVPKGTTASATSAASAASSSSSSFQPSPE 1097
APT A+ SP GG P A T AA+ S PSP+
Sbjct: 1190 SPKGAPT----TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238
Score = 55.8 bits (133), Expect = 3e-07
Identities = 140/663 (21%), Positives = 201/663 (30%), Gaps = 97/663 (14%)
Query: 17 SSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSEN--PRPPPRRDPST--R 72
++P + P PP+P+ L T PP P +T + PPP+ P+T
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177
Query: 73 RPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLT 132
PP G P+ A A P+P G ++ P +
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1237
Query: 133 RLSQDLQHSGVHLDCGGLRLSRPPAPPP-GDLQYSFFSSPSLANSIRSPEERATPHAKSE 191
+ + + GG P PPP G + PSL + +P + P+
Sbjct: 1238 KGAPTTPAATPPSPKGG-----PATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292
Query: 192 RPSHPLYEP-------EPEPRDSPQPGQGHSPGA-TAAATGLPPEPEPDSTDYSELADAD 243
P P P P P + P SPG PP P S + A
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352
Query: 244 ILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGE-----ALELP 298
S T P ++ PS + P + P P+ P P G+ + L
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK-RGPAIPSPKGDPTSPAVIPLS 1411
Query: 299 PLQPLADPLGLPGLALQAL-DTLPDSLESQLLDPQALDPLPK-LLDVPGRRLEPQQP--L 354
P + A P+ G A + D P ++ L PK P + +P P
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 355 GHCPLAEPLRLDLCSPHGP------PGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAG 408
P P + + P P P G P PK + R+
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV---PATPSSRRDPIA 1528
Query: 409 PEGRLLPLPMPTGLVAALAEPPP----PPPPPPPALPGPGPVSVPELKPESSQTPVVSTR 464
P LL P L A PP P P PA+P P E+S P V+
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT-- 1586
Query: 465 KGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMK 524
+TYK + L + PTP
Sbjct: 1587 -------------------------PSTYKGAPSPKELLIPPAVTSPSPKEAPTP----- 1616
Query: 525 NNGRNVVVVFPPGEMPIILKRKRGRP------PKNLLLGPGKPKEPAVVAAEAATVAAAT 578
V P E +G P P +L P P +V ATV A+
Sbjct: 1617 -----PAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP--ASVTCKMGATVPQAS 1669
Query: 579 MAMPEVKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCW 638
+P K K+ L +P P E + ++ Q++ + SPP C
Sbjct: 1670 KGLPAKKGPTALKEVLVAPAP-----------ESTPIITAPTRKGPQTKKSSATSPPICP 1718
Query: 639 TPS 641
PS
Sbjct: 1719 DPS 1721
Score = 53.1 bits (126), Expect = 2e-06
Identities = 115/468 (24%), Positives = 147/468 (31%), Gaps = 80/468 (17%)
Query: 13 SAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDK---AFSTHAFSENPRPPPRRDP 69
S SSP R G P +P P PPA+ P +T + P PP P
Sbjct: 912 SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971
Query: 70 STRRPPVL-AKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIM 128
S + P + P PP A P + TP G+ + P V
Sbjct: 972 SPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT-----------PPAV------ 1014
Query: 129 KDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHA 188
T S + G S PPA P + S ++P + +P AT +
Sbjct: 1015 ---TPPSPKGSPAATPFPKGA---STPPAATPPSPKGSPAATPLPKGAPTTP--AATLPS 1066
Query: 189 KSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATG--LPPEPEPDSTDYSELADADILS 246
P+ P + P P + P P AT + G +PP P S
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGP-ATPSPKGAPMPPAATPPS------------P 1113
Query: 247 ELASLTCPEAQLLEAQALEPPSPE-----PEPQLLDPQPRFLDPQALEPLGEALELPPLQ 301
+ T P A PPSP+ P P+ P P P G PP
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP---SPKGGLATPPPKG 1170
Query: 302 PLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPK-LLDVPGRRLEPQQPLGHCPLA 360
P P L T S + P A P PK L P + P P P
Sbjct: 1171 APTTPAATPPSPKGGLAT--PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP-- 1226
Query: 361 EPLRLDLCSPHG---PPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGR-LLPL 416
SP G P P+G P PK G A P+G P
Sbjct: 1227 --------SPKGGLATPSPKGAPTTPAATPPSPK----------GGPATPPPKGAPTPPA 1268
Query: 417 PMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELK-PESSQTPVVST 463
P L LA PP P P + P P P P+ + TP +T
Sbjct: 1269 ATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Score = 53.1 bits (126), Expect = 2e-06
Identities = 68/237 (28%), Positives = 87/237 (36%), Gaps = 33/237 (13%)
Query: 874 PPTSALPAQRG-LATFPSRGAKASPVAVGSSGAG--ADPSFQPVLSARQTFPPGRAASYG 930
PP + P+ +G LAT P +GA +P A S G A P + + PP
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1164
Query: 931 LTPAASDCRAAETFPKLVPP--------PSAMARSPTTHPPANTYLPQYGGYGAGQSVFA 982
P + A T P PP PS +PTT PA T GG A
Sbjct: 1165 TPPP----KGAPTTPAATPPSPKGGLATPSPKG-APTT--PAATPPSPKGGLATPSPKGA 1217
Query: 983 PTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSE 1042
PT P S A S P +P A P P GGP PP K + +
Sbjct: 1218 PTTPAA---TPPSPKGGLATPSPKGAPTTP-----AATPPSPKGGPATPPPKGAPTPPAA 1269
Query: 1043 GAPF--SGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPE 1097
P G A P + + V+P PKG ATS A + ++ PSP+
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPS---PKG--GPATSPPKGAPTPPAATPPSPK 1321
Score = 52.8 bits (125), Expect = 3e-06
Identities = 122/492 (24%), Positives = 156/492 (31%), Gaps = 83/492 (16%)
Query: 5 PQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPL-LPTRPPASPPDKAF--STHAFSENP 61
P+G+ + S + P GGP TP P PT P A+PP +T + P
Sbjct: 927 PKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAP 986
Query: 62 RPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCP--TPVGDGSSSRRCWDNGRVNLR 119
PP PS + P P A P S P TP G+S+
Sbjct: 987 TPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046
Query: 120 PVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRS 179
P + T + P+P G ++PSL +
Sbjct: 1047 PAATPLPKGAPTTPAAT------------------LPSPKGGP------ATPSLKGAPTP 1082
Query: 180 PEERATPHAKSERPSHPLYEPEPEPR----DSPQPGQGHSP--GATAAATGLPPEPE--- 230
P ATP + P+ P + P P SP+ G P GA PP P+
Sbjct: 1083 PA--ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 231 --PDSTDYSELADADILSELASLTCPEAQ-LLEAQALEPPSPEPEPQLLDPQPRFLDPQA 287
P A S L P + A PPSP+ P+ P A
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200
Query: 288 LEPL---GEALELP---PLQPLADPLGLPG-LALQALDTLPDSLESQLLDPQALDPLPKL 340
P G A P P P A P G LA + P + P A P PK
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT-------PAATPPSPK- 1252
Query: 341 LDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAG 400
G P + P A P L P +G P A+ PK
Sbjct: 1253 ---GGPATPPPKGAPTPPAATPPSLK--GGLATPPHKGAPNPAVVTPPSPK--------- 1298
Query: 401 RGRKADAGPEGRLLPL----PMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPEL---KP 453
G A + P+G P P P G + PPP P PPA+ P P P L P
Sbjct: 1299 -GGPATSPPKGAPTPPAATPPSPKG---SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354
Query: 454 ESSQTPVVSTRK 465
S P + K
Sbjct: 1355 SSKGGPTTPSSK 1366
Score = 52.4 bits (124), Expect = 4e-06
Identities = 74/259 (28%), Positives = 94/259 (36%), Gaps = 40/259 (15%)
Query: 859 ASRPESRKASGTYAGPPTSALPA---------QRGLATFPSRGAKASPVAVGSSGAG--A 907
A+ P S K G A PP P + GLAT P +GA +P A S G A
Sbjct: 1130 AATPPSPK--GGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 908 DPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPP--------PSAMARSPT 959
PS + + PP TP+ + A T P PP PS +PT
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLA-TPSP---KGAPTTPAATPPSPKGGLATPSPKG-APT 1242
Query: 960 THPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAY-GSGNSLPASPSSAHSA 1018
T PA T GG APT P + + G+ N +P S
Sbjct: 1243 T--PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGG 1300
Query: 1019 GYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGT-TAS 1077
PP G P P + S G P APTP V+P PKGT T
Sbjct: 1301 PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTP-------PAVTPPS---PKGTPTLP 1350
Query: 1078 ATSAASAASSSSSSFQPSP 1096
AT+ +S ++ S + P
Sbjct: 1351 ATTPSSKGGPTTPSSKEGP 1369
Score = 48.5 bits (114), Expect = 5e-05
Identities = 156/679 (22%), Positives = 215/679 (31%), Gaps = 131/679 (19%)
Query: 5 PQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPL-LPTRPPASPPDK----AFSTHAFSE 59
P+G T +A SP GGP TP P PT P A+PP A H +
Sbjct: 1237 PKGAPTTPAATPPSPK---------GGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP 1287
Query: 60 NPR----PPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGR 115
NP P P+ P+T P KG P PP A P + TP G+ +
Sbjct: 1288 NPAVVTPPSPKGGPATSPP----KGA-PTPPAATPPSPKGSPGTPPPKGAPTP------- 1335
Query: 116 VNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLAN 175
P V T + G PPA P + PS
Sbjct: 1336 ----PAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKR 1391
Query: 176 SIRSPEERATPHAKSERPSHPLYEPE-PEPRD---SPQPGQGHSPGATAAATGLPPEPE- 230
P + P + + P P P P R+ +P G P T + P
Sbjct: 1392 GPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 231 PDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEP 290
P + + D L ++T P + EPP+P+ P+ P P
Sbjct: 1452 PKGGPATPSSKGD--PTLPAVTPPSPK-------EPPAPKQVATSSSPKKA---PATPAP 1499
Query: 291 LGEALELPPLQPLADPLGLPGLALQALDTL-PDSLESQLLDPQALDP----LPKLLDVPG 345
+G A LP + P + P +P D + P + P L P +P + VP
Sbjct: 1500 MG-APTLPAVIP-SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 346 RRLEPQQPLGHCPLAEPLRLDLCSPHG--PPGPEGHPKYALRRTDRPKILCRRRKAGRGR 403
+ P P A P + SP P +G P
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPS---------------------- 1595
Query: 404 KADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVST 463
P+ L+P A+ P P P PPA+ P P P P TP
Sbjct: 1596 -----PKELLIP--------PAVTSPSPKEAPTPPAVTPPSPEKGP-ATPAPKGTP---- 1637
Query: 464 RKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKM 523
P SL + + T+ + +V GL PT L
Sbjct: 1638 ------------TSPPVTPSSL-KDSPTSPASVTCKMGATVPQASKGLPAKKGPTAL--- 1681
Query: 524 KNNGRNVVVVFPPGEMPIIL--KRKRGRPPKNLLLGPGKPKEPAV---VAAEAATVAAAT 578
+ V+V P PII RK + K+ P +P+ +TVA A
Sbjct: 1682 ----KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 579 MAMPEVKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAF---LNRQSQCAGRCSP- 634
+ + + K K AS P +SKA S L AF L + + +P
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKA--STPLTAAAFEKVLPKPESASVSAAPS 1795
Query: 635 PRCWTPSEPESVHQAPDTQ 653
P P P V P Q
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQ 1814
Score = 46.6 bits (109), Expect = 2e-04
Identities = 149/677 (22%), Positives = 211/677 (31%), Gaps = 108/677 (15%)
Query: 944 FPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYG 1003
FP P+ +A PTT +TY + G AP K+ G
Sbjct: 648 FPLESADPAGVA--PTTAKGTSTYTTTASPFLEGTVSLAP------------KNHPVKEG 693
Query: 1004 SGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSS------SEGAPFSGSAPTPLRCD 1057
+ +LP P+++ + AP P C P + S P +G+ P + D
Sbjct: 694 TLTTLPLVPTASENCPVAPSPQN-TCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVD 752
Query: 1058 --SRASTVSPGGYMVPKGTTASATSAASAASSSSSSF---QPSPENCRQFAGASQWPFRQ 1112
S S ++P + T + ++A+A+S + ++ PSP + P ++
Sbjct: 753 GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKK 812
Query: 1113 GYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQ 1172
G G D S +P + E ++ S +P T S + + S T
Sbjct: 813 GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVT- 871
Query: 1173 FNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPG 1232
P+ G E + S + A+ AP L +SS P
Sbjct: 872 ---PLSPKGVTLPPKETPTP------SVVNLPFPKEGPATPAPK---QAPALSMTSSSPK 919
Query: 1233 RGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQPRGGRGGG---------ACSAK 1283
+ R G P AS + G P+ + P P+GG A +
Sbjct: 920 KARATPAPK------GIP--ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971
Query: 1284 KERGGAAAKA-KFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSP---LPSQSRAFGVGERD 1339
+GG A + K P P P SP G S + +P P +
Sbjct: 972 SPKGGPATPSPKGAPTPPAATP---PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF 1028
Query: 1340 PCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGA------------PELDGKHFPPLAHPP 1387
P P + P +P +P+ A P L G PP A PP
Sbjct: 1029 PKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088
Query: 1388 TVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCR 1447
SP P + PP AA P G A H
Sbjct: 1089 -----------SPKGGPATPSPKGAPMPP---AATPPSPKG--------GLATPPHKGAP 1126
Query: 1448 DLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADF--LGRTEAACLSAPHL 1505
P P PS KG PP A +P G LA G + P
Sbjct: 1127 TTPAATP----PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 1506 ASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSL-LPLQDTAY 1564
ATP P A P P+G A + G P T P P+ L P A
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPSPKGAP 1241
Query: 1565 RYPGFMPQAHPGLGGGP 1581
P P P GGP
Sbjct: 1242 TTPAATP---PSPKGGP 1255
Score = 45.4 bits (106), Expect = 4e-04
Identities = 92/374 (24%), Positives = 130/374 (34%), Gaps = 53/374 (14%)
Query: 752 PEQVPSGPGFGEAGAEWAGDKGGGWAPHHG-HPGGQAGRNCGFQGTEARAFAS-----TG 805
P+ VPS P AG K G + P + + C + + A A AS T
Sbjct: 731 PKSVPS-PSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTY 789
Query: 806 LESGASGRGSYYSTGAPSGQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESR 865
L S G S T+ + G S + ++S L + +LS +
Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849
Query: 866 KASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPVLSA-RQTFP-- 922
A+ T++ P P+ +G T PS SP G P P S FP
Sbjct: 850 PAT-THSPTP----PSPKGAPT-PSAVTPLSP-----KGVTLPPKETPTPSVVNLPFPKE 898
Query: 923 ------PGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGA 976
P +A + +T ++ A PK +P + +PT PPA T GG
Sbjct: 899 GPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT--PPAATPPSPKGGPAT 956
Query: 977 GQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPT--GGPCLPPSK 1034
+APT P G SP A + A PP+ GGP P K
Sbjct: 957 PSPKWAPTPPAATPPSPK----------GGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006
Query: 1035 A----------SFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKG--TTASATSAA 1082
S S PF A TP + SP +PKG TT +AT +
Sbjct: 1007 GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066
Query: 1083 SAASSSSSSFQPSP 1096
++ S + +P
Sbjct: 1067 PKGGPATPSLKGAP 1080
Score = 44.3 bits (103), Expect = 0.001
Identities = 176/758 (23%), Positives = 254/758 (33%), Gaps = 160/758 (21%)
Query: 875 PTSAL---PAQRGLATFPS--RGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASY 929
P+S L P Q+ L T P+ GA SP G + DP+ P++ A P + S+
Sbjct: 519 PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLT-TKKDPTVLPLVQAA----PKNSPSF 573
Query: 930 GLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPFTG 989
T ++ + + P + +A+ P LP G+ + T P
Sbjct: 574 QSTSSSPEIPLS--------PEATLAKKSLGEP-----LP------IGKPASSMTSPL-- 612
Query: 990 QDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLP-----PSKASFFSSSEGA 1044
+ +S S + YA P + GP L P+ A+F E A
Sbjct: 613 -----------------GVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAF--PLESA 653
Query: 1045 PFSGSAPTPLRCDSRAST-----------VSPGGYMVPKGTTASATSAASAASSSSSSFQ 1093
+G APT + S +T ++P + V +GT + +A S +
Sbjct: 654 DPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTA--SENCPVA 711
Query: 1094 PSPEN-CRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQK 1152
PSP+N C A L A E + +PS TP
Sbjct: 712 PSPQNTCAPLAT------------LVLAPEIPKSVPSPSLP------------PAGTPPG 747
Query: 1153 VKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLS-SLEKLMMDWNEA 1211
K+ +S T + + S+ P G A++ ASS + L+ S L + +
Sbjct: 748 TKKVDGISHTSALAPVASSPKECPTEDSG---ASATASSKGTLTYLADSPSPLGVSVSPQ 804
Query: 1212 SSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPSK-RSTGPRQ 1270
+ P + P V EAS L + + + P+ S P
Sbjct: 805 TKRPPTKKGSA----GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPS 860
Query: 1271 PRGGRGGGACSAKKERGGAAAKAKFIPKPQPVN-PLFQDSPDLGLDYYSGDSSMSPLPSQ 1329
P+G A + +G K P P VN P ++ P +P P Q
Sbjct: 861 PKGAPTPSAVTPLSPKG-VTLPPKETPTPSVVNLPFPKEGP------------ATPAPKQ 907
Query: 1330 SRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTV 1389
+ A + P +TP+ +G GAP PP A PP+
Sbjct: 908 APALSMTSSSP-------KKARATPAP----KGIPASPSPKGAPT------PPAATPPS- 949
Query: 1390 FDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQ---GASLGHAAAAQAHLSC 1446
G SP +PT PP K P G A+ A S
Sbjct: 950 -PKGGPATPSPKWAPT---PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Query: 1447 RDLPLGQPHYDSPSCKGT--AYWYPPGS----AARSPPYEGKVGTGLLADFLGRTEAACL 1500
+ P P PS KG+ A +P G+ AA P +G L T AA L
Sbjct: 1006 KGAPT-PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATL 1064
Query: 1501 SAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSL-LPL 1559
+P PATP P A P P+G A + G P+ T P P+ L P
Sbjct: 1065 PSPK--GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAAT-PPSPKGGLATPP 1121
Query: 1560 QDTAYRYPGFMPQAHPGLGGG-----PKSGFLGPMAEP 1592
A P P P GG PK P A P
Sbjct: 1122 HKGAPTTPAATP---PSPKGGLATPPPKGAPTTPAATP 1156
Score = 42.0 bits (97), Expect = 0.005
Identities = 108/466 (23%), Positives = 148/466 (31%), Gaps = 68/466 (14%)
Query: 25 PKYYP--GGPPTPRPLLPTR----PPASPPDKAFSTHAF----SENPRPPPRRD-PSTRR 73
PK +P G T PL+PT P A P + A E P+ P P
Sbjct: 685 PKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGT 744
Query: 74 PPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNL---RPVVQLIDIMKD 130
PP K D A PV+ + P D +S G + P + +
Sbjct: 745 PPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804
Query: 131 LTRLSQDLQHSGVHLDCGGLRLSRPPAP------PPGDLQYSFFS-SPSLANSIRSPEER 183
R +G G L S P +P P L + SP+ +S P +
Sbjct: 805 TKRPPTKKGSAGPDTPIGNL--SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPK 862
Query: 184 ATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADAD 243
P + P P P P+++P P + LP E +T + A A
Sbjct: 863 GAPTPSAVTPLSPKGVTLP-PKETPTP----------SVVNLPFPKEGPATPAPKQAPA- 910
Query: 244 ILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQA--LEPLGEALELPPLQ 301
+ S + +A+ A P SP P+ P P+ P + PP
Sbjct: 911 --LSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA 968
Query: 302 PLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAE 361
P G P P + P PK P + P P G P A
Sbjct: 969 TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA-VTPPSPKGS-PAAT 1026
Query: 362 PLRLDLCSPHG--PPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMP 419
P +P PP P+G P T PK P LP P
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPA----ATPLPK---------------GAPTTPAATLPSP 1067
Query: 420 TGLVA--ALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTPVVST 463
G A +L P PP PP+ P GP + P+ + P +T
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPS-PKGGPATP---SPKGAPMPPAAT 1109
Score = 35.8 bits (81), Expect = 0.34
Identities = 61/269 (22%), Positives = 82/269 (30%), Gaps = 39/269 (14%)
Query: 859 ASRPESRKASGTYAGPPTSALP---------AQRGLATFPSRGAKASPVAVGSSGAGADP 909
A+ P S K G A PP P + G AT P +GA P A S G+ P
Sbjct: 1268 AATPPSLK--GGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS-P 1324
Query: 910 SFQPVLSARQ---TFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPT------- 959
P A PP + L + T P P+ A +P+
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
Query: 960 --THPPANTYLPQYGGYGAGQSVF------APTKPFTGQDCANSKDCSFAYGSGNSLPAS 1011
P +P G +V AP P T + A G +
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSK-----GDLTPPAVT 1439
Query: 1012 PSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVP 1071
P S A P GGP P SK + P P P + + +S P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 1072 KGTTASATSAASAASSSSSSFQPSPENCR 1100
G A + + SS +P + R
Sbjct: 1500 MG----APTLPAVIPSSPKEVPATPSSRR 1524
Score = 33.9 bits (76), Expect = 1.3
Identities = 87/360 (24%), Positives = 112/360 (31%), Gaps = 53/360 (14%)
Query: 1248 GFPTSASAAASGYPSKRSTGPRQP--RGGRGGGACSAKKERGGAAAKA-KFIPKPQPVNP 1304
G PT+ +A PS + GP P +G A + +GG A + K P P P
Sbjct: 1055 GAPTTPAATL---PSPKG-GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110
Query: 1305 LFQDSPDLGLDY--YSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQG 1362
SP GL + G + S G+ P + P +P G
Sbjct: 1111 ---PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG----- 1162
Query: 1363 FHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAAC 1422
L P G P A PP+ G SP +PT PP K
Sbjct: 1163 -------LATPPPKGAPTTPAATPPS--PKGGLATPSPKGAPTT---PAATPPSPKGGLA 1210
Query: 1423 EPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDS---PSCKGTAYWYPPGSAARSPPY 1479
P G + + L+ P G P + PS KG PP A P
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPS-PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
Query: 1480 EGKVGTGLLAD--FLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAG 1537
G LA G A ++ P PAT P A P P+G
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329
Query: 1538 YGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGP-----KSGFLGPMAEP 1592
G P +T P P+ + +P P GGP K G P A P
Sbjct: 1330 KGAPTPPAVT-PPSPKGT------------PTLPATTPSSKGGPTTPSSKEGPTPPAATP 1376
Score = 32.7 bits (73), Expect = 2.9
Identities = 87/344 (25%), Positives = 117/344 (34%), Gaps = 42/344 (12%)
Query: 1253 ASAAASGYPSKRSTGPRQPRGG------RGGG---ACSAKKERGGAAAKAKFIPKPQPVN 1303
A+ + G P+ + P P+GG +G A + +GG A + PK P
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS---PKGAPTT 1243
Query: 1304 PLFQD-SPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQG 1362
P SP G + +P + + G P P + PS +G
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSP----KG 1299
Query: 1363 FHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTK---- 1418
SP GAP PP A PP+ G P +PT + PP K
Sbjct: 1300 GPATSPPKGAPT------PPAATPPS--PKGSPGTPPPKGAPT---PPAVTPPSPKGTPT 1348
Query: 1419 LAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCK-GTAYWYPPGSAARSP 1477
L A P G G + + + G P PS K G A P G SP
Sbjct: 1349 LPATTPSSKG--GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT-SP 1405
Query: 1478 PYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAG 1537
A + R AA S L P TP + K+ + P G P P++
Sbjct: 1406 AVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK--- 1462
Query: 1538 YGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGP 1581
G P L +T P P++ P Q P P A P G P
Sbjct: 1463 -GDPTLPAVT-PPSPKEPPAPKQVATSSSPKKAP-ATPAPMGAP 1503
Score = 32.3 bits (72), Expect = 3.8
Identities = 72/297 (24%), Positives = 95/297 (31%), Gaps = 49/297 (16%)
Query: 1248 GFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQ 1307
G PT+ +A +T P P+G A + +GG A + PK P P
Sbjct: 1147 GAPTTPAATPPSPKGGLATPP--PKGAPTTPAATPPSPKGGLATPS---PKGAPTTPAAT 1201
Query: 1308 D-SPDLGLDYYS--GDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFH 1364
SP GL S G + S G+ P + P +P G
Sbjct: 1202 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP------ 1255
Query: 1365 CDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELR------PP--- 1415
P GAP PP A PP++ + +P + + PP
Sbjct: 1256 ATPPPKGAPT------PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
Query: 1416 PTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAAR 1475
PT AA P G G A P PS KGT P A
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTP------------PAVTPPSPKGT-----PTLPAT 1352
Query: 1476 SPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPA 1532
+P +G T + G T A + H P TP + K + P G P PA
Sbjct: 1353 TPSSKGGPTTPSSKE--GPTPPAATPS-HKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406
Score = 31.2 bits (69), Expect = 8.4
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 410 EGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVP-ELKPESSQTPVVST 463
E +LP+ + AAL +P P PPP P P+S + P S + + ST
Sbjct: 22 ETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 58.2 bits (139), Expect = 6e-08
Identities = 178/790 (22%), Positives = 269/790 (34%), Gaps = 117/790 (14%)
Query: 752 PEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGAS 811
P + G G G + + G GW+ G G +G++ GF E+ ++ S+G S
Sbjct: 1360 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGS 1419
Query: 812 GRG---SYYSTGAPSGQTELSQERQNLFTGYFRSLLDSDDSS------DLLDFALSASRP 862
G G SY G+ SGQ+ ER +G S S S
Sbjct: 1420 GSGHSSSYEQHGSRSGQSSRG-ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1478
Query: 863 ESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAG--ADPSFQPVLSARQT 920
SR G+ +G +S P G SRG S + SSG G S Q +
Sbjct: 1479 PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG-SSHSSGLGHRESRSGQSSGYGQHG 1537
Query: 921 FPPGRAASYG----LTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYG--GY 974
G ++++G + +S C S + S H ++ YG G
Sbjct: 1538 SSSGHSSTHGQHGSTSGQSSSCGQHGA-------SSGQSSSHGQHGSGSSQSSGYGRQGS 1590
Query: 975 GAGQSVFAPTKPFTGQDCANSKDC-SFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPS 1033
G+GQS P GQ + S+ S+ S +S S H +G G S
Sbjct: 1591 GSGQS------PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 1644
Query: 1034 KASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQ 1093
S S G+ SG + + SR+ S G S++ ++S S +
Sbjct: 1645 GQSSSYSQHGSG-SGHSSGYGQHGSRSGQSSRG------ERHGSSSRSSSRYGQHGSGSR 1697
Query: 1094 PSPENCRQFAGASQWPFRQGYG-GLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQK 1152
S + RQ +G+ Q P R +G GL +S S H S Y +
Sbjct: 1698 QSSGHGRQGSGSGQSPSRGRHGSGLGHSS---------SHGQHGSGSGRSSSRGPY--ES 1746
Query: 1153 VKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEAS 1212
++V S S+ ++Q G G + + S+ GQSS E + +
Sbjct: 1747 RSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSH 1806
Query: 1213 SAPGYNWNQSVLF-----QSSSKPGRGRRKKVDLFEASH----LGFPTSASAAASGYPSK 1263
G +QS + S P RGR +S+ G S+S+ G S
Sbjct: 1807 GQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG 1866
Query: 1264 RSTG-----------PRQPRGGRGGGACSAKKERG---GAAAKAKFIPKPQPVNPLF--- 1306
+S+G + G G G S+ ++ G G +++ + + +
Sbjct: 1867 QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQH 1926
Query: 1307 --QDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPY--------SMNPSTPSD 1356
LG + S SP PS+ R G G + GPY S P
Sbjct: 1927 GSGSRQSLGHGQHGSGSGQSPSPSRGR-HGSGSGQSSSY-GPYGSGSGWSSSRGPYESGS 1984
Query: 1357 GTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPP 1416
G H +S S G G+H H T G S +C
Sbjct: 1985 GHSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSASGQSSSC-------------- 2029
Query: 1417 TKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARS 1476
G GAS G +++ H S G S S + + GS +R
Sbjct: 2030 -----------GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG-QRGSGSRQ 2077
Query: 1477 PPYEGKVGTG 1486
P G+ G+G
Sbjct: 2078 SPSYGRHGSG 2087
Score = 57.8 bits (138), Expect = 8e-08
Identities = 165/780 (21%), Positives = 257/780 (32%), Gaps = 97/780 (12%)
Query: 647 HQAPDTQSISHFLH-----RVQGFRRRG---GKAGGFGGRGGG---------HAAKSARC 689
H A QS SH H + G+ R+G G++ G G RG G H + S R
Sbjct: 1562 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRS 1621
Query: 690 SFS-DFFEGIGKKKKVVAVAAAGVGGPGLTE--LGHPRKRGRGEVDAVTGKPKRKRRSRK 746
S S G+G+ ++ ++ G G G+ + +G+ R R
Sbjct: 1622 SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 1681
Query: 747 NGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNC--GFQGTEARAFAST 804
+ G G ++ G G +P G G G + G G+ + +S
Sbjct: 1682 SSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 1741
Query: 805 GLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYFRSL----LDSDDSSDLLDFALSAS 860
G SG S + + + +G+F S S SS S
Sbjct: 1742 GPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTG 1801
Query: 861 RPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSS-GAGADPSFQPVLSARQ 919
+ S G+ + +S G PSRG S SS G S S R
Sbjct: 1802 QSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRH 1861
Query: 920 TFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQS 979
G+++ +G ++S + T S+ + ++ Q+G S
Sbjct: 1862 GSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSS 1921
Query: 980 VFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPS-SAHSAGYAPPPTGGPCLPPSKASFF 1038
+ + Q + + +GSG+ SPS H +G + GP S +
Sbjct: 1922 SYGQHGSGSRQSLGHGQ-----HGSGSGQSPSPSRGRHGSGSGQSSSYGPY---GSGSGW 1973
Query: 1039 SSSEGAPFSGSAPTP--LRCDSRASTV-------SPGGYMVPKGTTASATSAASAASSSS 1089
SSS G SGS + +SR+ S G+ G SA+ +S+
Sbjct: 1974 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHG 2033
Query: 1090 SSFQPSPENCRQFAGASQWPFRQGYGGLDWAS--------EAFSQLYNPSFDCHVSEPNV 1141
+S S + + +G+SQ GYG S +PS+ H S
Sbjct: 2034 ASSGQSSSHGQHGSGSSQ---SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGR 2090
Query: 1142 ILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSL 1201
+ P +++ SS S+ ++Q G G + S GQSS
Sbjct: 2091 SSSSGQHGPG--LGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE- 2147
Query: 1202 EKLMMDWNEASSAPGYNWNQSVLFQSSS----------KPGRGRRKKVDLFEASHLGFPT 1251
+ + S+ Y + S QSS P RGR S G +
Sbjct: 2148 ----RHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGR-------HGSGSGHSS 2196
Query: 1252 SASAAASGYPSKRSTGPRQPRGGR---------GGGACSAKKERGGAAAKAKFIPKPQPV 1302
S SG S GP + R G G G SA + G + F + Q
Sbjct: 2197 SHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG--SGSGHFCSQGQHG 2254
Query: 1303 NPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQG 1362
+ Q S + + S + S G G + S + +PS G G G
Sbjct: 2255 STSGQSST------FDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSG 2308
Score = 57.0 bits (136), Expect = 1e-07
Identities = 135/576 (23%), Positives = 202/576 (35%), Gaps = 61/576 (10%)
Query: 752 PEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGAS 811
P + G G G + + G GW+ G G +G++ GF E+ ++ S+G S
Sbjct: 2300 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 2359
Query: 812 GRG---SYYSTGAPSGQTELSQERQNLFTGYFRSLLDSDDSS------DLLDFALSASRP 862
G G SY G+ SGQ+ ER +G S S S
Sbjct: 2360 GSGHSSSYEQHGSRSGQSSRG-ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 2418
Query: 863 ESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAG--ADPSFQPVLSARQT 920
SR G+ +G +S P G SRG S + SSG G S Q +
Sbjct: 2419 PSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESG-SGHSSGLGHRESRSGQSSGYGQHG 2477
Query: 921 FPPGRAASYG----LTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYG--GY 974
G ++++G + +S C S + S H ++ YG G
Sbjct: 2478 SSSGHSSTHGQHGSTSGQSSSCGQHGA-------SSGQSSSHGQHGSGSSQSSGYGRQGS 2530
Query: 975 GAGQSVFAPTKPFTGQDCANSKDC-SFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPS 1033
G+GQS P GQ + S+ S+ S +S S H +G G S
Sbjct: 2531 GSGQS------PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 2584
Query: 1034 KASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQ 1093
S S G+ SG + + SR+ S G S++ ++S S +
Sbjct: 2585 GQSSSYSQHGSG-SGHSSGYGQHGSRSGQSSRG------ERHGSSSGSSSHYGQHGSGSR 2637
Query: 1094 PSPENCRQFAGASQWPFRQGYG-GLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQK 1152
S + RQ +G+ Q P R +G GL +S S H S Y +
Sbjct: 2638 QSSGHGRQGSGSGQSPSRGRHGSGLGHSS---------SHGQHGSGSGRSSSRGPY--ES 2686
Query: 1153 VKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEAS 1212
++V S S+ ++Q G G + + S+ GQSS E +
Sbjct: 2687 RLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE-----GSSTG 2741
Query: 1213 SAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASH-LGFPTSASAAASGYPSKRSTGPRQP 1271
+ Y S QSS G L H G S+S G S +S+G Q
Sbjct: 2742 QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQH 2801
Query: 1272 RGGRGGGA---CSAKKERGGAAAKAKFIPKPQPVNP 1304
G G C G ++ + F+ P +P
Sbjct: 2802 GSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSSTSP 2837
Score = 54.7 bits (130), Expect = 7e-07
Identities = 172/789 (21%), Positives = 267/789 (33%), Gaps = 115/789 (14%)
Query: 752 PEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGAS 811
P + G G G + + G GW+ G G +G++ GF E+ ++ S+G S
Sbjct: 1830 PSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGS 1889
Query: 812 GRG---SYYSTGAPSGQTELSQERQNLF----------TGYFRSLLDSDDSSDLLDFALS 858
G G SY G+ SGQ+ ++ + +G +SL S
Sbjct: 1890 GSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGS-----GSG 1944
Query: 859 ASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAG--ADPSFQPVLS 916
S SR G+ +G +S P G SRG S + SSG G S Q
Sbjct: 1945 QSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESG-SGHSSGLGHRESRSGQSSGY 2003
Query: 917 ARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYG--GY 974
+ G ++++G +AS + S + S H ++ YG G
Sbjct: 2004 GQHGSSSGHSSTHGQHGSAS---GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
Query: 975 GAGQSVFAPTKPFTGQDCANSKDC-SFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPS 1033
G+GQS P GQ + S+ S+ S +S S H G G S
Sbjct: 2061 GSGQS------PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSS 2114
Query: 1034 KASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSSFQ 1093
S S G+ SG + + SR+ S G S++ ++S S +
Sbjct: 2115 GQSSSYSQHGSG-SGHSSGYGQHGSRSGQSSRG------ERHGSSSGSSSRYGQHGSGSR 2167
Query: 1094 PSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKV 1153
S + RQ +G+ P R +G S + Q + S P +
Sbjct: 2168 QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPY----------ESR 2217
Query: 1154 KQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASS 1213
++V S S+ ++Q G G + + S+ GQSS E + +
Sbjct: 2218 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG 2277
Query: 1214 APGYNWNQSVLF-----QSSSKPGRGRRKKVDLFEASH----LGFPTSASAAASGYPSKR 1264
G +QS + S P RGR +S+ G S+S+ G S +
Sbjct: 2278 QHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ 2337
Query: 1265 STG-----------PRQPRGGRGGGACSAKKERG---GAAAKAKFIPKPQPVNPLF---- 1306
S+G + G G G S+ ++ G G +++ + + +
Sbjct: 2338 SSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHG 2397
Query: 1307 -QDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPY--------SMNPSTPSDG 1357
LG + S SP PS+ R G G + PY S P G
Sbjct: 2398 SGSRQSLGHGQHGSGSGQSPSPSRGR-HGSGSGQSSSY-SPYGSGSGWSSSRGPYESGSG 2455
Query: 1358 TFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPT 1417
H +S S G G+H H T G S +C
Sbjct: 2456 HSSGLGHRESRS-GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC--------------- 2499
Query: 1418 KLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSP 1477
G GAS G +++ H S G S S + + GS +R
Sbjct: 2500 ----------GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHG-QRGSGSRQS 2548
Query: 1478 PYEGKVGTG 1486
P G+ G+G
Sbjct: 2549 PSYGRHGSG 2557
Score = 54.7 bits (130), Expect = 7e-07
Identities = 151/725 (20%), Positives = 237/725 (32%), Gaps = 123/725 (16%)
Query: 647 HQAPDTQSISHFLH-----RVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDFFEGIGKK 701
H A QS SH H + G+ R+G +G G G + S+ G G+
Sbjct: 2032 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRS 2091
Query: 702 KKVVAVAAAGVGGPGLTEL---------------------GHPRKRGRGEVDAVTGKPKR 740
+++G GPGL E G G G+ + +G+ R
Sbjct: 2092 ------SSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2145
Query: 741 KRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNC--GFQGTEA 798
R + G G ++ G G +P G G +G + G G+ +
Sbjct: 2146 GERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGS 2205
Query: 799 RAFASTGLESGASGRGSYYSTGAPSGQTELSQERQNLFTGYFRSL----LDSDDSSDLLD 854
+S G SG S + + + +G+F S S SS
Sbjct: 2206 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
Query: 855 FALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSS-GAGADPSFQP 913
S + S G+ + +S G PSRG S SS G S
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWS 2325
Query: 914 VLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGG 973
S R G+++ +G ++S + T S+ + ++ ++G
Sbjct: 2326 SSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGS 2385
Query: 974 YGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPS-------SAHSAGYAPPPTG 1026
S + + Q + + +GSG+ SPS S S+ Y+P +G
Sbjct: 2386 SSGSSSSYGQHGSGSRQSLGHGQ-----HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG 2440
Query: 1027 GPCLPPSKASFFSSSEGAPFSGSAPTP--LRCDSRASTV-------SPGGYMVPKGTTAS 1077
S +SSS G SGS + +SR+ S G+ G S
Sbjct: 2441 ---------SGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGS 2491
Query: 1078 ATSAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWAS--------EAFSQLYN 1129
+ +S+ +S S + + +G+SQ GYG S +
Sbjct: 2492 TSGQSSSCGQHGASSGQSSSHGQHGSGSSQ---SSGYGRQGSGSGQSPGHGQRGSGSRQS 2548
Query: 1130 PSFDCHVSEPNVILDISNYTPQKVKQQTAVSET-----FSESSSDSTQFNQPVGGGGFRR 1184
PS+ H S S + + + + E+ SS S+ ++Q G G
Sbjct: 2549 PSYGRHGSG-------SGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSS 2601
Query: 1185 ANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSS----------SKPGRG 1234
+ S GQSS + + S+ Y + S QSS P RG
Sbjct: 2602 GYGQHGSRSGQSSRGE-----RHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRG 2656
Query: 1235 RRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQPRGGR---------GGGACSAKKE 1285
R S LG +S SG S GP + R G G G SA +
Sbjct: 2657 R-------HGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQ 2709
Query: 1286 RGGAA 1290
G +
Sbjct: 2710 HGSGS 2714
Score = 48.9 bits (115), Expect = 4e-05
Identities = 150/689 (21%), Positives = 225/689 (32%), Gaps = 131/689 (19%)
Query: 670 GKAGGFGGRGGGHAAKSARCSFSDFFEGIGKKKKVVAVAAAGVGGPGLTELGHPRKRGRG 729
G G+ G H + S + S G G K + G G + RK G
Sbjct: 679 GSGSGWSSSNGPHGSVSGQSS------GFGHKSGSGQSSGYSQHGSGSSHSSGYRKHG-- 730
Query: 730 EVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPH---------- 779
+ +G+ R + + L G G ++ G G +P
Sbjct: 731 ---SRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGH 787
Query: 780 ---HGHPGG--QAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQERQN 834
HG G +CG + + + G SG+G Y G+ SG SQ R
Sbjct: 788 SSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQG-YSQHGSASGHFS-SQGRHG 845
Query: 835 LFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAK 894
+G S D SS S+S + AS +G G P G +
Sbjct: 846 STSGQSSSSGQHDSSS-----GQSSSYGQHESASHHASGRGRHG----SGSGQSPGHGQR 896
Query: 895 ASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAM 954
SG+G PS+ R GR++S G + S + S
Sbjct: 897 -------GSGSGQSPSY-----GRHGSGSGRSSSSGRHGSGSGQSSGFGHKS----SSGQ 940
Query: 955 ARSPTTHPPANTYLPQYGGYG--AGQS-------VFAPTKPFTGQDCANSKDC--SFAYG 1003
+ T H + + Y +G +GQS + + GQ + S+ +G
Sbjct: 941 SSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHG 1000
Query: 1004 SGNSLPASPS-SAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTP--LRCDSRA 1060
SG+ SPS H +G + GP S +SSS G SGS + +SR+
Sbjct: 1001 SGSGQSPSPSRGRHGSGSGQSSSYGPY---RSGSGWSSSRGPYESGSGHSSGLGHRESRS 1057
Query: 1061 STV-------SPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQFAGASQWPFRQG 1113
S G+ G S + +S+ +S S + + +G+SQ G
Sbjct: 1058 GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ---SSG 1114
Query: 1114 YGGLDWAS--------EAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSET--- 1162
YG S +PS+ H S S + + + + E+
Sbjct: 1115 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSG-------SGRSSSSGQHGSGLGESSGF 1167
Query: 1163 --FSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWN 1220
SS S+ ++Q G G + S GQSS + + S+ Y +
Sbjct: 1168 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSGSSSHYGQH 1222
Query: 1221 QSVLFQSSS----------KPGRGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQ 1270
S QSS P RGR S LG +S SG S GP +
Sbjct: 1223 GSGSRQSSGHGRQGSGSGHSPSRGR-------HGSGLGHSSSHGQHGSGSGRSSSRGPYE 1275
Query: 1271 PRGGR---------GGGACSAKKERGGAA 1290
R G G G SA + G +
Sbjct: 1276 SRSGHSSVFGQHESGSGHSSAYSQHGSGS 1304
Score = 47.0 bits (110), Expect = 1e-04
Identities = 167/749 (22%), Positives = 262/749 (34%), Gaps = 130/749 (17%)
Query: 584 VKKRRRRKQKLASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSPPRCWTPSEP 643
+ +R ++ + SY+ ++ + SD + QS G+C +P+
Sbjct: 155 ISRRLSFQRDFSGQHNSYSGQSSSYGEQNSD--------SHQSSGRGQCGSGSGQSPNYG 206
Query: 644 ESVHQAPDTQSISHFLH-----RVQGFRRR---GGKAGGFG--GRGGGHAAKSARCSFSD 693
+ H + QS S+ H + GF + G++ G+ G G GH++ +
Sbjct: 207 Q--HGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRS 264
Query: 694 FFEGIGKKKKVVAVAAAGVGGPGL---TELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTL 750
G++ + + +++ G G LGH R+ G G SR++
Sbjct: 265 GQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQ-GSG--------------SRQS--- 306
Query: 751 FPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGA 810
P V G G G + + G ++ GH +G+ GF E+ + S+G
Sbjct: 307 -PSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHG 365
Query: 811 SGRG---SYYSTGAPSGQTEL-----SQERQNLFTGYFRSLLDSDDSSDLLDFALSASRP 862
SG G S G+ SGQ S RQ+ G S S
Sbjct: 366 SGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG 425
Query: 863 ESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVG---SSGAGADPSFQPVLSARQ 919
++ SG+ P + Q G T R + + P G SSG G S S
Sbjct: 426 HGQRGSGSGQSPSS----GQHG--TGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYT 479
Query: 920 TFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYG------- 972
G S G S R+ ++ S R ++ +++Y Q+G
Sbjct: 480 QHGSGSGHSSGHGQHGS--RSGQS--------SRGERQGSSAGSSSSY-GQHGSGSRQSL 528
Query: 973 -----GYGAGQSVFAPTKPFTGQDCANSKDCS----FAYGSGNSLPASP---SSAHSAGY 1020
G G+GQS P G+ + S+ S YGSG S P S HS+G
Sbjct: 529 GHSRHGSGSGQS----PSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGL 584
Query: 1021 APPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATS 1080
+ S S G GS+ +ST G + ++
Sbjct: 585 G-----------HQESRSGQSSGYGQHGSS------SGHSSTHGQHGSTSGQSSSCGQHG 627
Query: 1081 AASAASSS----SSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHV 1136
A S SSS S S +Q +G+ Q P R +G S ++ Q + S
Sbjct: 628 ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSS 687
Query: 1137 SEP--NVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEG 1194
+ P +V S + + Q++ SS S+ + + G R S S G
Sbjct: 688 NGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRK----HGSRSGQSSRSEQHG 743
Query: 1195 QSS-LSSLEKLMMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASH--LGFPT 1251
SS LSS + SS G + S P R R +SH G T
Sbjct: 744 SSSGLSSSYGQHGSGSHQSSGHGRQGS-----GSGHSPSRVRHGSSSGHSSSHGQHGSGT 798
Query: 1252 SASAAASGYP--SKRSTGPRQPRGGRGGG 1278
S S++ Y S +++G Q G G G
Sbjct: 799 SCSSSCGHYESGSGQASGFGQHESGSGQG 827
Score = 45.4 bits (106), Expect = 4e-04
Identities = 177/805 (21%), Positives = 269/805 (33%), Gaps = 147/805 (18%)
Query: 647 HQAPDTQSISHFLH-----RVQGFRRRG---GKAGGFGGRGGG---------HAAKSARC 689
H A QS SH H + G+ R+G G++ G G RG G H + S R
Sbjct: 1092 HGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRS 1151
Query: 690 SFS-DFFEGIGKKKKVVAVAAAGVGGPGLTE--LGHPRKRGRGEVDAVTGKPKRKRRSRK 746
S S G+G+ ++ ++ G G G+ + +G+ R R
Sbjct: 1152 SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 1211
Query: 747 NGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPH-------------HGHPGGQAGRNCGF 793
+ G G ++ G G +P HG G +GR+
Sbjct: 1212 SSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 1271
Query: 794 QGTEARAFASTGL---ESGA----------SGRGSYYST---GAPSGQTELSQERQNLFT 837
E+R+ S+ ESG+ SG G + S G+ SGQ+ + +++ T
Sbjct: 1272 GPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSS-TFDQEGSST 1330
Query: 838 G----YFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGA 893
G Y S SS + + SR G+ +G +S G S G
Sbjct: 1331 GQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR 1390
Query: 894 KASPVAVGSS-GAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPS 952
S S G S+Q + G ++SY + S + + S
Sbjct: 1391 HGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRS---GQSSRGERHGSSS 1447
Query: 953 AMARSPTTHPPANTYLPQYG--GYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSL-- 1008
+ S H + +G G G+GQS +P++ G S S YGSG+
Sbjct: 1448 GSSSSYGQHGSGSRQSLGHGQHGSGSGQSP-SPSRGRHGSGSGQSSSYS-PYGSGSGWSS 1505
Query: 1009 ---PASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSP 1065
P S+HS+G + S S G GS+ +ST
Sbjct: 1506 SRGPYESGSSHSSGLG-----------HRESRSGQSSGYGQHGSS------SGHSSTHGQ 1548
Query: 1066 GGYMVPKGTTASATSAASAASSS----SSSFQPSPENCRQFAGASQWPFRQGYGGLDWAS 1121
G + ++ A+S SSS S S RQ +G+ Q P G+G
Sbjct: 1549 HGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSP---GHG-----Q 1600
Query: 1122 EAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSET-----FSESSSDSTQFNQP 1176
+PS+ H S S + + + + E+ SS S+ ++Q
Sbjct: 1601 RGSGSRQSPSYGRHGSG-------SGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 1653
Query: 1177 VGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAPGYNWNQSVLFQSS-------- 1228
G G + S GQSS + + S+ Y + S QSS
Sbjct: 1654 GSGSGHSSGYGQHGSRSGQSSRGE-----RHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708
Query: 1229 --SKPGRGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQPRGGR---------GG 1277
P RGR S LG +S SG S GP + R G G
Sbjct: 1709 SGQSPSRGR-------HGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGS 1761
Query: 1278 GACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGE 1337
G SA + G + F + Q + Q S + + S + S G G
Sbjct: 1762 GHSSAYSQHG--SGSGHFCSQGQHGSTSGQSST------FDQEGSSTGQSSSHGQHGSGS 1813
Query: 1338 RDPCDFIGPYSMNPSTPSDGTFGQG 1362
+ S + +PS G G G
Sbjct: 1814 SQSSSYGQQGSGSGQSPSRGRHGSG 1838
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 57.4 bits (137), Expect = 1e-07
Identities = 67/249 (26%), Positives = 89/249 (35%), Gaps = 61/249 (24%)
Query: 267 PSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLES 326
P+P P P P P L +L + PP+ P P P ALQA
Sbjct: 322 PTPPPPPP---PLPSALSTSSLRASMTSTPPPPVPPPPPP---PATALQA---------- 365
Query: 327 QLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRR 386
A+ P P L + L P P PL +P PP
Sbjct: 366 -----PAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP---------SPP------------ 399
Query: 387 TDRPKILCRRRKAGRGRKADAGPEGRLLPL-PMPTGLVAALAEPPPPPPPPPPALPGPGP 445
A A P +P+ P+P G V L PPPPPP PPP + P
Sbjct: 400 -----------------VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSP 442
Query: 446 VSVPEL-KPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSV 504
V+V L P S P ST G + IP S +R+ +T V S + S+ +
Sbjct: 443 VTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLL 502
Query: 505 EGKELGLRV 513
E G+++
Sbjct: 503 EAIRKGIQL 511
Score = 46.2 bits (108), Expect = 3e-04
Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 26/227 (11%)
Query: 152 LSRPPAPPPGDLQYSFFSSPSLANSIRSP----EERATPHAKSERPSHPLYEPEPEPRDS 207
L RP PPP + + + I S E R A P P P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPV--FVSPTPPPPPP 329
Query: 208 PQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPP 267
P P + A+ T PP P P A + ++ P A L A + P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPPPPATA-----LQAPAVPPPPAPLQIAPGVLHP 384
Query: 268 SPEP-EPQLLDPQPRFLD--------PQALEPLGEALELPPLQPLADPLGLPGLALQALD 318
+P P P L+ P P P P GE LPP P PL PG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIR----P 439
Query: 319 TLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGH-CPLAEPLR 364
+ P ++ + P L P P P L P P P +EP R
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR 486
Score = 31.6 bits (70), Expect = 6.5
Identities = 53/208 (25%), Positives = 65/208 (31%), Gaps = 54/208 (25%)
Query: 18 SPDYLREPKYYPGGPPTPRPLLP--------------TRPPASPPDKAFSTHAFSENPRP 63
SP R P + PP P P LP T PP PP A + P
Sbjct: 310 SPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL-QAPAV 368
Query: 64 PPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQ 123
PP P P VL P PP A P+ Q P+P PV +
Sbjct: 369 PPPPAPLQIAPGVL----HPAPPPIAPPLVQ---PSP-------------------PVAR 402
Query: 124 LIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFF--SSPSLANSIRSPE 181
+ + + VH G PP PPP L SSP ++ P
Sbjct: 403 AAPVCETVP----------VHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP 452
Query: 182 ERATPHAKSERPSH-PLYEPEPEPRDSP 208
P + H PL P P + P
Sbjct: 453 SGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
Score = 31.6 bits (70), Expect = 6.5
Identities = 36/148 (24%), Positives = 55/148 (37%), Gaps = 15/148 (10%)
Query: 3 VKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENP- 61
V+P V ++ VC + P+ G P P P P PP P + A + P
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPS 453
Query: 62 --RPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQ-ARCPTPVGDGSSSRRCWDNGRVNL 118
P P P P + P PP P S+ R P+ + S +R V L
Sbjct: 454 GLHPTPSTAPGPHVPLM-----PPSPPSQVIPASEPKRHPSTLPVISDAR------SVLL 502
Query: 119 RPVVQLIDIMKDLTRLSQDLQHSGVHLD 146
+ + I + K + Q+ +H + D
Sbjct: 503 EAIRKGIQLRKVEEQREQEAKHERIEND 530
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 57.4 bits (137), Expect = 1e-07
Identities = 67/249 (26%), Positives = 89/249 (35%), Gaps = 61/249 (24%)
Query: 267 PSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLES 326
P+P P P P P L +L + PP+ P P P ALQA
Sbjct: 322 PTPPPPPP---PLPSALSTSSLRASMTSTPPPPVPPPPPP---PATALQA---------- 365
Query: 327 QLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRR 386
A+ P P L + L P P PL +P PP
Sbjct: 366 -----PAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP---------SPP------------ 399
Query: 387 TDRPKILCRRRKAGRGRKADAGPEGRLLPL-PMPTGLVAALAEPPPPPPPPPPALPGPGP 445
A A P +P+ P+P G V L PPPPPP PPP + P
Sbjct: 400 -----------------VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSP 442
Query: 446 VSVPEL-KPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSV 504
V+V L P S P ST G + IP S +R+ +T V S + S+ +
Sbjct: 443 VTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLL 502
Query: 505 EGKELGLRV 513
E G+++
Sbjct: 503 EAIRKGIQL 511
Score = 46.2 bits (108), Expect = 3e-04
Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 26/227 (11%)
Query: 152 LSRPPAPPPGDLQYSFFSSPSLANSIRSP----EERATPHAKSERPSHPLYEPEPEPRDS 207
L RP PPP + + + I S E R A P P P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPV--FVSPTPPPPPP 329
Query: 208 PQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPP 267
P P + A+ T PP P P A + ++ P A L A + P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPPPPATA-----LQAPAVPPPPAPLQIAPGVLHP 384
Query: 268 SPEP-EPQLLDPQPRFLD--------PQALEPLGEALELPPLQPLADPLGLPGLALQALD 318
+P P P L+ P P P P GE LPP P PL PG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIR----P 439
Query: 319 TLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGH-CPLAEPLR 364
+ P ++ + P L P P P L P P P +EP R
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR 486
Score = 31.6 bits (70), Expect = 6.5
Identities = 53/208 (25%), Positives = 65/208 (31%), Gaps = 54/208 (25%)
Query: 18 SPDYLREPKYYPGGPPTPRPLLP--------------TRPPASPPDKAFSTHAFSENPRP 63
SP R P + PP P P LP T PP PP A + P
Sbjct: 310 SPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL-QAPAV 368
Query: 64 PPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQ 123
PP P P VL P PP A P+ Q P+P PV +
Sbjct: 369 PPPPAPLQIAPGVL----HPAPPPIAPPLVQ---PSP-------------------PVAR 402
Query: 124 LIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFF--SSPSLANSIRSPE 181
+ + + VH G PP PPP L SSP ++ P
Sbjct: 403 AAPVCETVP----------VHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP 452
Query: 182 ERATPHAKSERPSH-PLYEPEPEPRDSP 208
P + H PL P P + P
Sbjct: 453 SGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
Score = 31.6 bits (70), Expect = 6.5
Identities = 36/148 (24%), Positives = 55/148 (37%), Gaps = 15/148 (10%)
Query: 3 VKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENP- 61
V+P V ++ VC + P+ G P P P P PP P + A + P
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPS 453
Query: 62 --RPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQ-ARCPTPVGDGSSSRRCWDNGRVNL 118
P P P P + P PP P S+ R P+ + S +R V L
Sbjct: 454 GLHPTPSTAPGPHVPLM-----PPSPPSQVIPASEPKRHPSTLPVISDAR------SVLL 502
Query: 119 RPVVQLIDIMKDLTRLSQDLQHSGVHLD 146
+ + I + K + Q+ +H + D
Sbjct: 503 EAIRKGIQLRKVEEQREQEAKHERIEND 530
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 57.4 bits (137), Expect = 1e-07
Identities = 67/249 (26%), Positives = 89/249 (35%), Gaps = 61/249 (24%)
Query: 267 PSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLES 326
P+P P P P P L +L + PP+ P P P ALQA
Sbjct: 322 PTPPPPPP---PLPSALSTSSLRASMTSTPPPPVPPPPPP---PATALQA---------- 365
Query: 327 QLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRR 386
A+ P P L + L P P PL +P PP
Sbjct: 366 -----PAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP---------SPP------------ 399
Query: 387 TDRPKILCRRRKAGRGRKADAGPEGRLLPL-PMPTGLVAALAEPPPPPPPPPPALPGPGP 445
A A P +P+ P+P G V L PPPPPP PPP + P
Sbjct: 400 -----------------VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSP 442
Query: 446 VSVPEL-KPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSV 504
V+V L P S P ST G + IP S +R+ +T V S + S+ +
Sbjct: 443 VTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLL 502
Query: 505 EGKELGLRV 513
E G+++
Sbjct: 503 EAIRKGIQL 511
Score = 46.2 bits (108), Expect = 3e-04
Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 26/227 (11%)
Query: 152 LSRPPAPPPGDLQYSFFSSPSLANSIRSP----EERATPHAKSERPSHPLYEPEPEPRDS 207
L RP PPP + + + I S E R A P P P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPV--FVSPTPPPPPP 329
Query: 208 PQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPP 267
P P + A+ T PP P P A + ++ P A L A + P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPPPPATA-----LQAPAVPPPPAPLQIAPGVLHP 384
Query: 268 SPEP-EPQLLDPQPRFLD--------PQALEPLGEALELPPLQPLADPLGLPGLALQALD 318
+P P P L+ P P P P GE LPP P PL PG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIR----P 439
Query: 319 TLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGH-CPLAEPLR 364
+ P ++ + P L P P P L P P P +EP R
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR 486
Score = 31.6 bits (70), Expect = 6.5
Identities = 53/208 (25%), Positives = 65/208 (31%), Gaps = 54/208 (25%)
Query: 18 SPDYLREPKYYPGGPPTPRPLLP--------------TRPPASPPDKAFSTHAFSENPRP 63
SP R P + PP P P LP T PP PP A + P
Sbjct: 310 SPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL-QAPAV 368
Query: 64 PPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQ 123
PP P P VL P PP A P+ Q P+P PV +
Sbjct: 369 PPPPAPLQIAPGVL----HPAPPPIAPPLVQ---PSP-------------------PVAR 402
Query: 124 LIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFF--SSPSLANSIRSPE 181
+ + + VH G PP PPP L SSP ++ P
Sbjct: 403 AAPVCETVP----------VHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP 452
Query: 182 ERATPHAKSERPSH-PLYEPEPEPRDSP 208
P + H PL P P + P
Sbjct: 453 SGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
Score = 31.6 bits (70), Expect = 6.5
Identities = 36/148 (24%), Positives = 55/148 (37%), Gaps = 15/148 (10%)
Query: 3 VKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENP- 61
V+P V ++ VC + P+ G P P P P PP P + A + P
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPS 453
Query: 62 --RPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQ-ARCPTPVGDGSSSRRCWDNGRVNL 118
P P P P + P PP P S+ R P+ + S +R V L
Sbjct: 454 GLHPTPSTAPGPHVPLM-----PPSPPSQVIPASEPKRHPSTLPVISDAR------SVLL 502
Query: 119 RPVVQLIDIMKDLTRLSQDLQHSGVHLD 146
+ + I + K + Q+ +H + D
Sbjct: 503 EAIRKGIQLRKVEEQREQEAKHERIEND 530
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 57.4 bits (137), Expect = 1e-07
Identities = 67/249 (26%), Positives = 89/249 (35%), Gaps = 61/249 (24%)
Query: 267 PSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLES 326
P+P P P P P L +L + PP+ P P P ALQA
Sbjct: 322 PTPPPPPP---PLPSALSTSSLRASMTSTPPPPVPPPPPP---PATALQA---------- 365
Query: 327 QLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRR 386
A+ P P L + L P P PL +P PP
Sbjct: 366 -----PAVPPPPAPLQIAPGVLHPAPPPIAPPLVQP---------SPP------------ 399
Query: 387 TDRPKILCRRRKAGRGRKADAGPEGRLLPL-PMPTGLVAALAEPPPPPPPPPPALPGPGP 445
A A P +P+ P+P G V L PPPPPP PPP + P
Sbjct: 400 -----------------VARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSP 442
Query: 446 VSVPEL-KPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSV 504
V+V L P S P ST G + IP S +R+ +T V S + S+ +
Sbjct: 443 VTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKRHPSTLPVISDARSVLL 502
Query: 505 EGKELGLRV 513
E G+++
Sbjct: 503 EAIRKGIQL 511
Score = 46.2 bits (108), Expect = 3e-04
Identities = 60/227 (26%), Positives = 77/227 (33%), Gaps = 26/227 (11%)
Query: 152 LSRPPAPPPGDLQYSFFSSPSLANSIRSP----EERATPHAKSERPSHPLYEPEPEPRDS 207
L RP PPP + + + I S E R A P P P P
Sbjct: 272 LVRPHEPPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPATGRTPV--FVSPTPPPPPP 329
Query: 208 PQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPP 267
P P + A+ T PP P P A + ++ P A L A + P
Sbjct: 330 PLPSALSTSSLRASMTSTPPPPVPPPPPPPATA-----LQAPAVPPPPAPLQIAPGVLHP 384
Query: 268 SPEP-EPQLLDPQPRFLD--------PQALEPLGEALELPPLQPLADPLGLPGLALQALD 318
+P P P L+ P P P P GE LPP P PL PG+
Sbjct: 385 APPPIAPPLVQPSPPVARAAPVCETVPVHPLPQGEVQGLPP-PPPPPPLPPPGIR----P 439
Query: 319 TLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGH-CPLAEPLR 364
+ P ++ + P L P P P L P P P +EP R
Sbjct: 440 SSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPPSQVIPASEPKR 486
Score = 31.6 bits (70), Expect = 6.5
Identities = 53/208 (25%), Positives = 65/208 (31%), Gaps = 54/208 (25%)
Query: 18 SPDYLREPKYYPGGPPTPRPLLP--------------TRPPASPPDKAFSTHAFSENPRP 63
SP R P + PP P P LP T PP PP A + P
Sbjct: 310 SPATGRTPVFVSPTPPPPPPPLPSALSTSSLRASMTSTPPPPVPPPPPPPATAL-QAPAV 368
Query: 64 PPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQ 123
PP P P VL P PP A P+ Q P+P PV +
Sbjct: 369 PPPPAPLQIAPGVL----HPAPPPIAPPLVQ---PSP-------------------PVAR 402
Query: 124 LIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFF--SSPSLANSIRSPE 181
+ + + VH G PP PPP L SSP ++ P
Sbjct: 403 AAPVCETVP----------VHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPP 452
Query: 182 ERATPHAKSERPSH-PLYEPEPEPRDSP 208
P + H PL P P + P
Sbjct: 453 SGLHPTPSTAPGPHVPLMPPSPPSQVIP 480
Score = 31.6 bits (70), Expect = 6.5
Identities = 36/148 (24%), Positives = 55/148 (37%), Gaps = 15/148 (10%)
Query: 3 VKPQGLVVTSSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENP- 61
V+P V ++ VC + P+ G P P P P PP P + A + P
Sbjct: 394 VQPSPPVARAAPVCETVPVHPLPQGEVQGLPPPPPPPPLPPPGIRPSSPVTVTALAHPPS 453
Query: 62 --RPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQ-ARCPTPVGDGSSSRRCWDNGRVNL 118
P P P P + P PP P S+ R P+ + S +R V L
Sbjct: 454 GLHPTPSTAPGPHVPLM-----PPSPPSQVIPASEPKRHPSTLPVISDAR------SVLL 502
Query: 119 RPVVQLIDIMKDLTRLSQDLQHSGVHLD 146
+ + I + K + Q+ +H + D
Sbjct: 503 EAIRKGIQLRKVEEQREQEAKHERIEND 530
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 57.4 bits (137), Expect = 1e-07
Identities = 86/316 (27%), Positives = 113/316 (35%), Gaps = 82/316 (25%)
Query: 172 SLANSIRSPEERATPHAKSERPSHPLYEPE---------PEPRDSPQPG--QGHSPGATA 220
S + SI SP++ + S + +P P P +P PG Q +PG T
Sbjct: 156 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-PGTPQLPTPGPTP 214
Query: 221 AATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQAL---EPPSPEPEPQLLD 277
+AT +PP+ P + + A + + P + +A AL PPSP P P
Sbjct: 215 SATAVPPQGSPTA------SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH--- 265
Query: 278 PQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPL 337
P P PPLQPL G P A L P +L
Sbjct: 266 PSPH----------------PPLQPLTGSAGQPSAPSHAQPPLHGQGPP---GPHSLQAG 306
Query: 338 PKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRR 397
P LL PG P QP G P A + +P G +P +L+ L ++
Sbjct: 307 P-LLQHPG----PPQPFGLPPQASQGQ----APLGTSPAAAYPHTSLQLPASQSALQSQQ 357
Query: 398 KAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPP----------PPALPGPGPVS 447
R PLP P L +PPP P P PP L GP P S
Sbjct: 358 PP------------REQPLP-PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 404
Query: 448 V-------PELKPESS 456
+ P LKP SS
Sbjct: 405 MNANLPPPPALKPLSS 420
Score = 53.1 bits (126), Expect = 2e-06
Identities = 102/450 (22%), Positives = 136/450 (30%), Gaps = 113/450 (25%)
Query: 29 PGGPPTP-----RPLLPTRP-PASPPDKAFSTHAFSE-NPRPPPRRDPSTRRPPVLAKGD 81
P G PT +P PT P P + +A + H +P PPP P P+
Sbjct: 221 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAG 280
Query: 82 DPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHS 141
P P A+P + P
Sbjct: 281 QPSAPSHAQPPLHGQGPP------------------------------------------ 298
Query: 142 GVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP----EERATPHAKSERP-SHP 196
G H G L P P P F P A+ ++P A PH + P S
Sbjct: 299 GPHSLQAGPLLQHPGPPQP-------FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 351
Query: 197 LYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEA 256
+ + PR+ P P A +P P +T +L L+ P
Sbjct: 352 ALQSQQPPREQPLP---------PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP 402
Query: 257 QLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELP--PLQPLADPLGLPGLAL 314
+ A PP+ +P L P P L+ + ++ LP P QP PGL
Sbjct: 403 FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP-------PGLT- 454
Query: 315 QALDTLPDSLESQLLDPQALDPLP----KLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSP 370
+SQ L P P ++ P P P G P+ P +P
Sbjct: 455 ----------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 504
Query: 371 HGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAAL---A 427
PG P C A G A G PLP AL
Sbjct: 505 PAGPGTSAQPP------------CSGAAASGGSIAG----GSSCPLPTVQIKEEALDDAE 548
Query: 428 EPPPPPPPPPPALPGPGPVSVPELKPESSQ 457
EP PPPPP P P V P +S++
Sbjct: 549 EPESPPPPPRSPSPEPTVVDTPSHASQSAR 578
Score = 40.0 bits (92), Expect = 0.018
Identities = 52/192 (27%), Positives = 67/192 (34%), Gaps = 37/192 (19%)
Query: 1346 PYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPP--TVFDAGLQKAYSPTCS 1403
P+SMN + P P+L H PP AHPP + SP
Sbjct: 402 PFSMNANLPPP-----------PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 450
Query: 1404 PTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRD-LPLGQPHYDSPSCK 1462
P L + L PPP H G H A Q + +P G P P+C
Sbjct: 451 PGLTQSQNLPPPPA--------SHPPTGL---HQVAPQPPFAQHPFVPGGPPPITPPTCP 499
Query: 1463 GTAYWYPPGSAARS--PPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLE 1520
T+ PP S PP G + G + A S P L + +A + E
Sbjct: 500 STS--TPPAGPGTSAQPPCSGAAAS-------GGSIAGGSSCP-LPTVQIKEEALDDAEE 549
Query: 1521 MARPPGPPRGPA 1532
PP PPR P+
Sbjct: 550 PESPPPPPRSPS 561
Score = 33.9 bits (76), Expect = 1.3
Identities = 95/436 (21%), Positives = 141/436 (32%), Gaps = 79/436 (18%)
Query: 1170 STQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAP--GYNWNQSVLFQS 1227
++ N+ + G R + S AS+S S +++K E +S+P + +
Sbjct: 45 TSPINEDIRSSG-RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASD 103
Query: 1228 SSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPS---------------KRSTGPRQPR 1272
+ + R KK E S P+ +S S RST P P
Sbjct: 104 TEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPS 163
Query: 1273 GGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSM-SPLPSQSR 1331
+ ++ A+ + P V P +P G + +P P+ S
Sbjct: 164 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP-------GTPQLPTPGPTPSA 216
Query: 1332 AFGVGERDPCDFIGPYSMN-PSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHP---- 1386
+ P P P+ P T Q +P+L H PP P
Sbjct: 217 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ----QAPALHPQRPPSPHPPPHPSPHPPL 272
Query: 1387 -PTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLG---HAAAAQA 1442
P AG A S P G + P P L A L+H G A+ QA
Sbjct: 273 QPLTGSAGQPSAPSHAQPPLHG---QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 329
Query: 1443 HLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAA---RSPPYEGKVGTGLLADFLGRTEAAC 1499
L PH T+ P +A + PP E + A
Sbjct: 330 PLGTSPAA-AYPH--------TSLQLPASQSALQSQQPPREQPL------------PPAP 368
Query: 1500 LSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPL 1559
L+ PH+ PP TP + + P GP+ P + L P P +L PL
Sbjct: 369 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS--------PFSMNANLPPPP--ALKPL 418
Query: 1560 QDTAYRYPGFMPQAHP 1575
+ +P P AHP
Sbjct: 419 SSLSTHHP---PSAHP 431
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 57.4 bits (137), Expect = 1e-07
Identities = 86/316 (27%), Positives = 113/316 (35%), Gaps = 82/316 (25%)
Query: 172 SLANSIRSPEERATPHAKSERPSHPLYEPE---------PEPRDSPQPG--QGHSPGATA 220
S + SI SP++ + S + +P P P +P PG Q +PG T
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-PGTPQLPTPGPTP 768
Query: 221 AATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQAL---EPPSPEPEPQLLD 277
+AT +PP+ P + + A + + P + +A AL PPSP P P
Sbjct: 769 SATAVPPQGSPTA------SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH--- 819
Query: 278 PQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPL 337
P P PPLQPL G P A L P +L
Sbjct: 820 PSPH----------------PPLQPLTGSAGQPSAPSHAQPPLHGQGPP---GPHSLQAG 860
Query: 338 PKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRR 397
P LL PG P QP G P A + +P G +P +L+ L ++
Sbjct: 861 P-LLQHPG----PPQPFGLPPQASQGQ----APLGTSPAAAYPHTSLQLPASQSALQSQQ 911
Query: 398 KAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPP----------PPALPGPGPVS 447
R PLP P L +PPP P P PP L GP P S
Sbjct: 912 PP------------REQPLP-PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958
Query: 448 V-------PELKPESS 456
+ P LKP SS
Sbjct: 959 MNANLPPPPALKPLSS 974
Score = 53.1 bits (126), Expect = 2e-06
Identities = 102/450 (22%), Positives = 136/450 (30%), Gaps = 113/450 (25%)
Query: 29 PGGPPTP-----RPLLPTRP-PASPPDKAFSTHAFSE-NPRPPPRRDPSTRRPPVLAKGD 81
P G PT +P PT P P + +A + H +P PPP P P+
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAG 834
Query: 82 DPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHS 141
P P A+P + P
Sbjct: 835 QPSAPSHAQPPLHGQGPP------------------------------------------ 852
Query: 142 GVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP----EERATPHAKSERP-SHP 196
G H G L P P P F P A+ ++P A PH + P S
Sbjct: 853 GPHSLQAGPLLQHPGPPQP-------FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 905
Query: 197 LYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEA 256
+ + PR+ P P A +P P +T +L L+ P
Sbjct: 906 ALQSQQPPREQPLP---------PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP 956
Query: 257 QLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELP--PLQPLADPLGLPGLAL 314
+ A PP+ +P L P P L+ + ++ LP P QP PGL
Sbjct: 957 FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP-------PGLT- 1008
Query: 315 QALDTLPDSLESQLLDPQALDPLP----KLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSP 370
+SQ L P P ++ P P P G P+ P +P
Sbjct: 1009 ----------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058
Query: 371 HGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAAL---A 427
PG P C A G A G PLP AL
Sbjct: 1059 PAGPGTSAQPP------------CSGAAASGGSIAG----GSSCPLPTVQIKEEALDDAE 1102
Query: 428 EPPPPPPPPPPALPGPGPVSVPELKPESSQ 457
EP PPPPP P P V P +S++
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSAR 1132
Score = 40.0 bits (92), Expect = 0.018
Identities = 52/192 (27%), Positives = 67/192 (34%), Gaps = 37/192 (19%)
Query: 1346 PYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPP--TVFDAGLQKAYSPTCS 1403
P+SMN + P P+L H PP AHPP + SP
Sbjct: 956 PFSMNANLPPP-----------PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 1004
Query: 1404 PTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRD-LPLGQPHYDSPSCK 1462
P L + L PPP H G H A Q + +P G P P+C
Sbjct: 1005 PGLTQSQNLPPPPA--------SHPPTGL---HQVAPQPPFAQHPFVPGGPPPITPPTCP 1053
Query: 1463 GTAYWYPPGSAARS--PPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLE 1520
T+ PP S PP G + G + A S P L + +A + E
Sbjct: 1054 STS--TPPAGPGTSAQPPCSGAAAS-------GGSIAGGSSCP-LPTVQIKEEALDDAEE 1103
Query: 1521 MARPPGPPRGPA 1532
PP PPR P+
Sbjct: 1104 PESPPPPPRSPS 1115
Score = 33.9 bits (76), Expect = 1.3
Identities = 95/436 (21%), Positives = 141/436 (32%), Gaps = 79/436 (18%)
Query: 1170 STQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAP--GYNWNQSVLFQS 1227
++ N+ + G R + S AS+S S +++K E +S+P + +
Sbjct: 599 TSPINEDIRSSG-RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASD 657
Query: 1228 SSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPS---------------KRSTGPRQPR 1272
+ + R KK E S P+ +S S RST P P
Sbjct: 658 TEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPS 717
Query: 1273 GGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSM-SPLPSQSR 1331
+ ++ A+ + P V P +P G + +P P+ S
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP-------GTPQLPTPGPTPSA 770
Query: 1332 AFGVGERDPCDFIGPYSMN-PSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHP---- 1386
+ P P P+ P T Q +P+L H PP P
Sbjct: 771 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ----QAPALHPQRPPSPHPPPHPSPHPPL 826
Query: 1387 -PTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLG---HAAAAQA 1442
P AG A S P G + P P L A L+H G A+ QA
Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHG---QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883
Query: 1443 HLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAA---RSPPYEGKVGTGLLADFLGRTEAAC 1499
L PH T+ P +A + PP E + A
Sbjct: 884 PLGTSPAA-AYPH--------TSLQLPASQSALQSQQPPREQPL------------PPAP 922
Query: 1500 LSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPL 1559
L+ PH+ PP TP + + P GP+ P + L P P +L PL
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS--------PFSMNANLPPPP--ALKPL 972
Query: 1560 QDTAYRYPGFMPQAHP 1575
+ +P P AHP
Sbjct: 973 SSLSTHHP---PSAHP 985
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 57.4 bits (137), Expect = 1e-07
Identities = 86/316 (27%), Positives = 113/316 (35%), Gaps = 82/316 (25%)
Query: 172 SLANSIRSPEERATPHAKSERPSHPLYEPE---------PEPRDSPQPG--QGHSPGATA 220
S + SI SP++ + S + +P P P +P PG Q +PG T
Sbjct: 710 STSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP-PGTPQLPTPGPTP 768
Query: 221 AATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQAL---EPPSPEPEPQLLD 277
+AT +PP+ P + + A + + P + +A AL PPSP P P
Sbjct: 769 SATAVPPQGSPTA------SQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPH--- 819
Query: 278 PQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPL 337
P P PPLQPL G P A L P +L
Sbjct: 820 PSPH----------------PPLQPLTGSAGQPSAPSHAQPPLHGQGPP---GPHSLQAG 860
Query: 338 PKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRR 397
P LL PG P QP G P A + +P G +P +L+ L ++
Sbjct: 861 P-LLQHPG----PPQPFGLPPQASQGQ----APLGTSPAAAYPHTSLQLPASQSALQSQQ 911
Query: 398 KAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPP----------PPALPGPGPVS 447
R PLP P L +PPP P P PP L GP P S
Sbjct: 912 PP------------REQPLP-PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958
Query: 448 V-------PELKPESS 456
+ P LKP SS
Sbjct: 959 MNANLPPPPALKPLSS 974
Score = 53.1 bits (126), Expect = 2e-06
Identities = 102/450 (22%), Positives = 136/450 (30%), Gaps = 113/450 (25%)
Query: 29 PGGPPTP-----RPLLPTRP-PASPPDKAFSTHAFSE-NPRPPPRRDPSTRRPPVLAKGD 81
P G PT +P PT P P + +A + H +P PPP P P+
Sbjct: 775 PQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAG 834
Query: 82 DPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHS 141
P P A+P + P
Sbjct: 835 QPSAPSHAQPPLHGQGPP------------------------------------------ 852
Query: 142 GVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSP----EERATPHAKSERP-SHP 196
G H G L P P P F P A+ ++P A PH + P S
Sbjct: 853 GPHSLQAGPLLQHPGPPQP-------FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQS 905
Query: 197 LYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEA 256
+ + PR+ P P A +P P +T +L L+ P
Sbjct: 906 ALQSQQPPREQPLP---------PAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSP 956
Query: 257 QLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELP--PLQPLADPLGLPGLAL 314
+ A PP+ +P L P P L+ + ++ LP P QP PGL
Sbjct: 957 FSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP-------PGLT- 1008
Query: 315 QALDTLPDSLESQLLDPQALDPLP----KLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSP 370
+SQ L P P ++ P P P G P+ P +P
Sbjct: 1009 ----------QSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058
Query: 371 HGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAAL---A 427
PG P C A G A G PLP AL
Sbjct: 1059 PAGPGTSAQPP------------CSGAAASGGSIAG----GSSCPLPTVQIKEEALDDAE 1102
Query: 428 EPPPPPPPPPPALPGPGPVSVPELKPESSQ 457
EP PPPPP P P V P +S++
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSAR 1132
Score = 40.0 bits (92), Expect = 0.018
Identities = 52/192 (27%), Positives = 67/192 (34%), Gaps = 37/192 (19%)
Query: 1346 PYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPP--TVFDAGLQKAYSPTCS 1403
P+SMN + P P+L H PP AHPP + SP
Sbjct: 956 PFSMNANLPPP-----------PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 1004
Query: 1404 PTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRD-LPLGQPHYDSPSCK 1462
P L + L PPP H G H A Q + +P G P P+C
Sbjct: 1005 PGLTQSQNLPPPPA--------SHPPTGL---HQVAPQPPFAQHPFVPGGPPPITPPTCP 1053
Query: 1463 GTAYWYPPGSAARS--PPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLE 1520
T+ PP S PP G + G + A S P L + +A + E
Sbjct: 1054 STS--TPPAGPGTSAQPPCSGAAAS-------GGSIAGGSSCP-LPTVQIKEEALDDAEE 1103
Query: 1521 MARPPGPPRGPA 1532
PP PPR P+
Sbjct: 1104 PESPPPPPRSPS 1115
Score = 33.9 bits (76), Expect = 1.3
Identities = 95/436 (21%), Positives = 141/436 (32%), Gaps = 79/436 (18%)
Query: 1170 STQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEASSAP--GYNWNQSVLFQS 1227
++ N+ + G R + S AS+S S +++K E +S+P + +
Sbjct: 599 TSPINEDIRSSG-RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASD 657
Query: 1228 SSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPS---------------KRSTGPRQPR 1272
+ + R KK E S P+ +S S RST P P
Sbjct: 658 TEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPS 717
Query: 1273 GGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSM-SPLPSQSR 1331
+ ++ A+ + P V P +P G + +P P+ S
Sbjct: 718 PQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP-------GTPQLPTPGPTPSA 770
Query: 1332 AFGVGERDPCDFIGPYSMN-PSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHP---- 1386
+ P P P+ P T Q +P+L H PP P
Sbjct: 771 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ----QAPALHPQRPPSPHPPPHPSPHPPL 826
Query: 1387 -PTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLG---HAAAAQA 1442
P AG A S P G + P P L A L+H G A+ QA
Sbjct: 827 QPLTGSAGQPSAPSHAQPPLHG---QGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883
Query: 1443 HLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAA---RSPPYEGKVGTGLLADFLGRTEAAC 1499
L PH T+ P +A + PP E + A
Sbjct: 884 PLGTSPAA-AYPH--------TSLQLPASQSALQSQQPPREQPL------------PPAP 922
Query: 1500 LSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPL 1559
L+ PH+ PP TP + + P GP+ P + L P P +L PL
Sbjct: 923 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS--------PFSMNANLPPPP--ALKPL 972
Query: 1560 QDTAYRYPGFMPQAHP 1575
+ +P P AHP
Sbjct: 973 SSLSTHHP---PSAHP 985
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 57.0 bits (136), Expect = 1e-07
Identities = 120/491 (24%), Positives = 185/491 (37%), Gaps = 75/491 (15%)
Query: 856 ALSASRPESRKASGTYA-----GPPTSALPAQRGLATFPSR--GAKASPVAVGSSGAGAD 908
A R S KA G A G PT +P+ LA PS G+K SP A A
Sbjct: 2329 ARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTP-LALEPSSTPGSKKSPPEPVDKRAKA- 2386
Query: 909 PSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYL 968
P +P PP + + PA + C A E F +L P +++A +P PA
Sbjct: 2387 PKARPA-------PPQPSPA---PPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPK 2436
Query: 969 PQYGGYGAGQSVFAPTKP-----------FTGQDCANSKDCSFAY------GSGNSLPAS 1011
P+ P +P G SK A G+G
Sbjct: 2437 PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGW--QE 2494
Query: 1012 PSSAHSAGYAPPPTGG--PCLPPSKASFFSSSE----GAPF--SGSAPTPLRCDSRASTV 1063
P S S G PP G P P KA+ ++ G F SG+ +P +A
Sbjct: 2495 PKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSP----DKAQAE 2550
Query: 1064 SPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQFAGASQWPFRQGYGGLDWASEA 1123
G +++S+ S++S++SSSSS + E G G GG + S A
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEE----EGDKNGDGGCGTGGRN-CSAA 2605
Query: 1124 FSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDSTQFNQPVGGGGFR 1183
S+ +P+ S S+ + ++ S + S SSS S+ +
Sbjct: 2606 SSRAASPASSSSSS--------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2657
Query: 1184 RANSEASSSEGQSSLSSLEKLMMDWNEASSAP--GYNWNQSVLFQSSSKPGRGRRKKVDL 1241
++S +SSS SS + + +EA+ AP G + ++ +++ + G+ R
Sbjct: 2658 SSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARP----- 2712
Query: 1242 FEASHLGFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQP 1301
A G T A + P + T P QP+ + G KK G K + K Q
Sbjct: 2713 -SAHSPGKKTPAPQPQA--PPPQPTQPLQPK-AQAGAKSRPKKREGVHLPTTKELAKRQR 2768
Query: 1302 VNPLFQDSPDL 1312
+ P ++ P +
Sbjct: 2769 L-PSVENRPKI 2778
Score = 47.4 bits (111), Expect = 1e-04
Identities = 58/216 (26%), Positives = 84/216 (38%), Gaps = 15/216 (6%)
Query: 714 GPGLT--ELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGD 771
GPGLT + G+P+ + + + + S +G+ S G E E GD
Sbjct: 2530 GPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSG-SETEGEEEGD 2588
Query: 772 KGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQE 831
K G G GRNC + A + AS+ S +S S S+ + S + S
Sbjct: 2589 KNGDGGC------GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642
Query: 832 RQNLFTGYFRSLLDSDDSSDLLDFALSASR--PESRKASGTYAGP-PTSALPAQRGLATF 888
+ + S S SS + S+S +S +S A P PT+ AQ L T
Sbjct: 2643 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTK 2702
Query: 889 PSRGA-KASPVAVGSSGAGADPSFQPVLSARQTFPP 923
++ A KA P A S P+ QP Q P
Sbjct: 2703 ATKQAGKARPSA--HSPGKKTPAPQPQAPPPQPTQP 2736
Score = 37.0 bits (84), Expect = 0.15
Identities = 109/439 (24%), Positives = 156/439 (35%), Gaps = 88/439 (20%)
Query: 398 KAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQ 457
+AGRG +A + L T + P P P PPPPA P GP + P P
Sbjct: 299 EAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPPA-PPKGPPAPPAATPAGVY 357
Query: 458 TPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEP 517
T + +G VV +P S+ ++ + S + +E
Sbjct: 358 TVF------REQGREHRVVAPTFVP-SVEAFDERPGPIQIASQARDARARE--------- 401
Query: 518 TPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAA 577
+ GR V+ PPG P L R G KN ++ K P A+A TV A
Sbjct: 402 ------REAGRPGVLQAPPGS-PRPLDRPEGLREKNSVIRSLKRPPP----ADAPTV-RA 449
Query: 578 TMAMPEVKKRRRRKQKL---ASPQPSYAADANDSKAEYSDVLAKLAFLNRQSQCAGRCSP 634
T A P+ + K+ L A P+P A + + AKL L GR P
Sbjct: 450 TRASPDPRAYVPAKELLKPEADPRPCERAPRGPA-GPAAQQAAKLFGLE-----PGR--P 501
Query: 635 PRCWTPSEPESVHQAPDTQSISHFLHRVQGFRRRGGKAGGFGGRGGGHAAKSARCSFSDF 694
P P+ PE + + + + V + +A AA S++ ++ D
Sbjct: 502 P----PTGPEHKWKPFELGNFAATQMAVLAAQHHHSRA---EEEAAVVAASSSKKAYLD- 553
Query: 695 FEGIGKKKKVVAVAAAGVGGPGLTELGHPRKRGRGEV---------------DAVTGKP- 738
V+ +AA G P + ++ H G GE DAV +P
Sbjct: 554 ------PGAVLPRSAATCGRP-VADM-HSAAHGSGEASAMQSLIKYSGSFARDAVAVRPG 605
Query: 739 --KRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQAGRNC---GF 793
+K GT+ PE P+ G A A PH G P GR
Sbjct: 606 GCGKKSPFGGLGTMKPEPAPTSAGASRAQAR---------LPHSGGPAAGGGRQLKRDPE 656
Query: 794 QGTEARAFASTGLESGASG 812
+ A+AF G SGA G
Sbjct: 657 RPESAKAFGREG--SGAQG 673
Score = 36.6 bits (83), Expect = 0.20
Identities = 59/258 (22%), Positives = 93/258 (36%), Gaps = 36/258 (13%)
Query: 58 SENPRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVN 117
+E P PR PS PP P PP A TP G + R RV
Sbjct: 321 TETLLPGPRPCPSPLPPPPAPPKGPPAPPAA----------TPAGVYTVFREQGREHRVV 370
Query: 118 LRPVVQLIDIMKD------LTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSP 171
V ++ + + ++D + G+ + P +P P D
Sbjct: 371 APTFVPSVEAFDERPGPIQIASQARDARAREREAGRPGVLQAPPGSPRPLDRPEGLREKN 430
Query: 172 SLANSIRSPEE---------RATPHAKSERPSHPLYEPEPEPRDSPQPGQGHS-PGATAA 221
S+ S++ P RA+P ++ P+ L +PE +PR + +G + P A A
Sbjct: 431 SVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPAGPAAQQA 490
Query: 222 AT--GLPP-EPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLL-- 276
A GL P P P ++ EL + + +L AQ + E +
Sbjct: 491 AKLFGLEPGRPPPTGPEHKWKP-----FELGNFAATQMAVLAAQHHHSRAEEEAAVVAAS 545
Query: 277 DPQPRFLDPQALEPLGEA 294
+ +LDP A+ P A
Sbjct: 546 SSKKAYLDPGAVLPRSAA 563
Score = 31.2 bits (69), Expect = 8.4
Identities = 41/158 (25%), Positives = 52/158 (32%), Gaps = 23/158 (14%)
Query: 1412 LRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPG 1471
L PP K+ EP A L +A ++ + +D G+ GTA PG
Sbjct: 2279 LLPPDYKIQCAEP-----SPALLVPSAKRRSRKTSKDTGEGKDG-------GTAGSEEPG 2326
Query: 1472 SAARS---PPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARP---- 1524
+ AR P G G S P P +TP + K P E
Sbjct: 2327 AKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKA 2386
Query: 1525 ----PGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLP 1558
P PP+ A A CP P P SL P
Sbjct: 2387 PKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAP 2424
Score = 31.2 bits (69), Expect = 8.4
Identities = 34/158 (21%), Positives = 54/158 (34%), Gaps = 15/158 (9%)
Query: 169 SSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPE 228
SS S ++S S ++ + S S S S ++++++ E
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDE 2675
Query: 229 PEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQAL 288
S+D E A A A P +A P + P + PQP+ PQ
Sbjct: 2676 DSSCSSD-DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQAPPPQPT 2734
Query: 289 EPL--------------GEALELPPLQPLADPLGLPGL 312
+PL E + LP + LA LP +
Sbjct: 2735 QPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSV 2772
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 56.6 bits (135), Expect = 2e-07
Identities = 118/515 (22%), Positives = 179/515 (34%), Gaps = 100/515 (19%)
Query: 853 LDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQ 912
L A AS P S A T P +L + + P A + PS
Sbjct: 312 LPAAAPASPPTSLLAPST--NPLLESLKKMQTPPSLPPCPESAGAATTEALSPPKTPSLL 369
Query: 913 PVLSARQTFPPGRAASYGLTPAAS-DCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQY 971
P L Q+ PPG L P+ S D + T L+P PS + + T PP
Sbjct: 370 PPLGLSQSGPPG------LLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPT------- 416
Query: 972 GGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLP 1031
TKP + + SF +G+ N+ P+SP +A +A APP
Sbjct: 417 ------LQAETATKPQATSAPSPAPKQSFLFGTQNTSPSSP-AAPAASSAPPMFKPIFTA 469
Query: 1032 PSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSSSSS 1091
P K S EG PTP PG + T S++S + S+++ +
Sbjct: 470 PPK----SEKEG-------PTP-----------PGPSVT--ATAPSSSSLPTTTSTTAPT 505
Query: 1092 FQPSPENCRQFAGASQWPFRQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQ 1151
FQP +S P + + F Q P+ + P +T
Sbjct: 506 FQP--------VFSSMGP----PASVPLPAPFFKQTTTPATAPTTTAP-------LFTGL 546
Query: 1152 KVKQQTAVSETFSESSSDSTQFNQPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWNEA 1211
T + S+DS ++P G G +S + S+ ++ ++ + + +A
Sbjct: 547 ASATSAVAPITSASPSTDSA--SKPAFGFGINSVSSSSVSTTTSTATAASQPFLFGAPQA 604
Query: 1212 SSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEAS-HLGFPTSASAAASGYPSKRSTGPRQ 1270
S+A + +FQ P V F S H PT+ S++A+ + ST
Sbjct: 605 SAA-SFTPAMGSIFQFGKPPALPTTTTVTTFSQSLHTAVPTATSSSAADFSGFGST---- 659
Query: 1271 PRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPS-- 1328
A A + +P + + G S+ SPLPS
Sbjct: 660 ------------------LATSAPATSSQPTLTFSNTSTPTFNIPF--GSSAKSPLPSYP 699
Query: 1329 ---QSRAFGVGERDPCDFIGPYSMNPSTPSDGTFG 1360
AFG E P P ++ PS S TFG
Sbjct: 700 GANPQPAFGAAEGQPPGAAKP-ALAPSFGSSFTFG 733
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 56.2 bits (134), Expect = 2e-07
Identities = 118/501 (23%), Positives = 160/501 (31%), Gaps = 78/501 (15%)
Query: 17 SSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPV 76
SSP L P PG +P P+ + P ASP S S P P P+ P+
Sbjct: 1398 SSP--LHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPL 1455
Query: 77 LAKGDDPLPPRAARPVSQARCPTPVGD-------------------------GSSSRRCW 111
PL A+ P P+ G ++
Sbjct: 1456 TIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSL 1515
Query: 112 DNGRVNLRPVVQLIDIMKDLTRLSQDLQH--SGVHLDCGGLRLSRPPAPPPGDLQYSFFS 169
+ + P++ L + L+ + S V + L P AP P Q S +
Sbjct: 1516 SSSQTPGHPLL-LAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLA 1574
Query: 170 SPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATAA-ATGLPPE 228
S A+ + ATP A P + P P P +P P SPGA A+ P
Sbjct: 1575 PASSAS-----QALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPV 1629
Query: 229 P--EPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQ 286
P P ST + LA A + + P + L P P P P Q L P
Sbjct: 1630 PVMAPSSTPGTSLASASPVPAPTPVLAPSST---QTMLPAPVPSPLPSPASTQTLALAPA 1686
Query: 287 ALEPLGEALELPPLQPLADPLGLPG-------LALQALDTL-PDSLESQLLDP-QALDPL 337
LG + P Q L+ G P L+L +L P ++ L P L P
Sbjct: 1687 LAPTLGGS---SPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPT 1743
Query: 338 PKLLDVPGRRLEPQQPLGHCP--------------LAEPLRLDLCSPHGPPGPEGHPKYA 383
L P L P P+G P L P + + P P P A
Sbjct: 1744 QTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAA 1803
Query: 384 LRRTDRPKILCRRRKAGRGRKADAGPEGRL-LPLPMPTGLVAALAEP--------PPPPP 434
P + A + G LP+ M + L + EP PP PP
Sbjct: 1804 QTLALAPA--STQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPP 1861
Query: 435 PPPPALPGPGPVSVPELKPES 455
+ GP P P P S
Sbjct: 1862 STATSFGGPRPRRQPPPPPRS 1882
Score = 45.8 bits (107), Expect = 3e-04
Identities = 70/268 (26%), Positives = 86/268 (32%), Gaps = 23/268 (8%)
Query: 160 PGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLY-----EPEPEPRDSPQPGQGH 214
PG S P + I P E A + P P E SP+ G G
Sbjct: 2788 PGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGA 2847
Query: 215 ----SPGATAAATGLPPEPEPDSTDYSELADADILSELASLTC-------PEAQLLEAQA 263
+P A G PP+ D D S L T PE ++
Sbjct: 2848 LLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPV 2907
Query: 264 LEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDS 323
LEP P PQ L PQP L P+ + P P A L +PG A D +S
Sbjct: 2908 LEPQLI-PGPQPLGPQPVHRPNPLLSPVEKRRRGRP--PKARDLPIPGTISSAGDGNSES 2964
Query: 324 LESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYA 383
P L PLP LL P + + P R P PP P
Sbjct: 2965 RTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPV 3024
Query: 384 LRRTDRPKILCRRRKAGRGRKADAGPEG 411
L R D +L G GR+ +G
Sbjct: 3025 LDR-DSTSVL---ESCGLGRRRQPQGQG 3048
Score = 42.0 bits (97), Expect = 0.005
Identities = 116/447 (25%), Positives = 144/447 (32%), Gaps = 97/447 (21%)
Query: 29 PGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPS------TRRPPVLAKGDD 82
P PTP +LP+ P++ P + + N PP + + R+ P G
Sbjct: 1265 PTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAP--RDGLT 1322
Query: 83 PLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSG 142
P+PP A P R P SS N R L P
Sbjct: 1323 PVPPLAPAP----RPP------SSGLPAVLNPRPTLTP---------------------- 1350
Query: 143 VHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERP---SHPLYE 199
L L +R P P P ++ L + SP + A P S PL+
Sbjct: 1351 GRLPTPTLGTARAPMPTPTLVR-------PLLKLVHSPSPEVSASAPGAAPLTISSPLHV 1403
Query: 200 PE--PEPRDSPQPGQGHSPGAT--AAATGLPPEPE-PDSTDYSELADADILSELASLTCP 254
P P P SP P SP A+ ++ +P P S + A A A LT P
Sbjct: 1404 PSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPAS-----APLTIP 1458
Query: 255 EAQLLEAQALEPP-SPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLA 313
+ L A P P L P P +L P G + P A L L GLA
Sbjct: 1459 ISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGAS-------PSASALTL-GLA 1510
Query: 314 LQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGP 373
T P SQ PG L H P CSP
Sbjct: 1511 -----TAPSLSSSQ---------------TPGHPLLLAPTSSHVPGLNSTVAPACSPVLV 1550
Query: 374 PGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPP 433
P + P A +A A P L P+ P A LA P PP
Sbjct: 1551 PASALASPFPSAPNPAPAQASLLAPASSASQALATP---LAPMAAPQ--TAILAPSPAPP 1605
Query: 434 PPPPPALPGPGPVSVPELKPESSQTPV 460
P P L P P + P L SSQTPV
Sbjct: 1606 LAPLPVL-APSPGAAPVL--ASSQTPV 1629
Score = 41.2 bits (95), Expect = 0.008
Identities = 71/266 (26%), Positives = 94/266 (35%), Gaps = 29/266 (10%)
Query: 860 SRPESRKASG----TYAGPPTS-ALPAQRGLATFPSRGAKASPVAVGSSGAGADPSFQPV 914
S P + ASG T PP + +PA G + GA S A+ A A P
Sbjct: 1460 SAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATA-----PS 1514
Query: 915 LSARQTFPPGR----AASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQ 970
LS+ QT PG A + P + A P LVP + + P+ PA
Sbjct: 1515 LSSSQT--PGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASL 1572
Query: 971 YG-GYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAP----PPT 1025
A Q++ P P A A L P A S G AP T
Sbjct: 1573 LAPASSASQALATPLAPMAAPQTA-----ILAPSPAPPLAPLPVLAPSPGAAPVLASSQT 1627
Query: 1026 GGPCLPPSKASFFSSSEGAPFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAA 1085
P + PS S + +P APTP+ S T+ P P + AS + A A
Sbjct: 1628 PVPVMAPSSTPGTSLASASPV--PAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP 1685
Query: 1086 SSSSSSFQPSPENCRQF-AGASQWPF 1110
+ + + SP G Q PF
Sbjct: 1686 ALAPTLGGSSPSQTLSLGTGNPQGPF 1711
Score = 38.9 bits (89), Expect = 0.040
Identities = 40/136 (29%), Positives = 54/136 (39%), Gaps = 19/136 (13%)
Query: 334 LDPLPKLLDVPGRRL----EPQQPLGHCPLAEPLRLDLCSPHGP-PGPEGHPKYALRRTD 388
L P+PK GR + P+ PLG P+ P +L + P P P+ P +
Sbjct: 998 LQPVPKQ---EGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSAS 1054
Query: 389 R--PKILCRRRKAGRGRKADAGPEGRLLP--LPMPTGLVAALAEPP-------PPPPPPP 437
P ++ R G P LP LP P G+++ + PP P PP P
Sbjct: 1055 PAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPV 1114
Query: 438 PALPGPGPVSVPELKP 453
P P P S LKP
Sbjct: 1115 RLSPAPPPGSSSLLKP 1130
Score = 38.9 bits (89), Expect = 0.040
Identities = 57/247 (23%), Positives = 90/247 (36%), Gaps = 19/247 (7%)
Query: 860 SRPESRKASGTYAGPPTSALPAQ-----RGLATFPSRGAKASPVAVGSSGAGADPSFQPV 914
S P + S T + P +S+LP A+ P ++P+ V +SG S P
Sbjct: 1420 SSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPP 1479
Query: 915 LSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHP----PANTYLPQ 970
L+ PG + L P+ + A+ L PS + HP P ++++P
Sbjct: 1480 LAPVVPAAPGPPS---LAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVP- 1535
Query: 971 YGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCL 1030
G +V P A + A + + + A SA A P
Sbjct: 1536 ----GLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMA 1591
Query: 1031 PPSKASFFSSSEG--APFSGSAPTPLRCDSRASTVSPGGYMVPKGTTASATSAASAASSS 1088
P A S AP AP+P AS+ +P M P T ++ ++AS +
Sbjct: 1592 APQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAP 1651
Query: 1089 SSSFQPS 1095
+ PS
Sbjct: 1652 TPVLAPS 1658
Score = 38.1 bits (87), Expect = 0.069
Identities = 73/304 (24%), Positives = 102/304 (33%), Gaps = 84/304 (27%)
Query: 301 QPLADPLGLPG-------LALQALDTLPDSLESQLLDPQALDPLPKLLDVPGR--RLEPQ 351
+P+ P PG L L+A D P Q +D D L+ + GR R E
Sbjct: 910 RPVTSPFITPGICFSTASLVLRATDVHP----LQRIDMGRFD----LIGLEGRVSRYEAD 961
Query: 352 QPLGHCPLAEPLRLDLCSPHGPPGPEGHPKYALRRTDRPK--------ILCRRRKAGRGR 403
L L+ + L++ + PP K + R +P ++ +A G
Sbjct: 962 TFLPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGP 1021
Query: 404 ---KADAGPEGRLLPLPMPTGLV---AALAEPPPPPPPPPPALPGPGPVSVPELKPESSQ 457
+ GPE P P P V + + P PP PA PGPV +P L+P S
Sbjct: 1022 VPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGS 1081
Query: 458 TPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEP 517
P V +P LG + T S P
Sbjct: 1082 LPQV-------------------LPSPLGVLSGT----------------------SRPP 1100
Query: 518 TPLLKMKNNGRNVVVVF---PPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATV 574
TP L +K V + PPG ++ K L + PG PA + T
Sbjct: 1101 TPTLSLKPTPPAPVRLSPAPPPGSSSLL---------KPLTVPPGYTFPPAAATTTSTTT 1151
Query: 575 AAAT 578
A AT
Sbjct: 1152 ATAT 1155
Score = 37.7 bits (86), Expect = 0.090
Identities = 140/672 (20%), Positives = 204/672 (30%), Gaps = 183/672 (27%)
Query: 41 TRPPASPPDKAFSTHAFSENPRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTP 100
TR +PP + A PRP PR P+ P P+P A P+S P P
Sbjct: 2420 TRSTTTPPR---CSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPIS---APNP 2473
Query: 101 VGDGSSSRRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPP 160
+ + PV L P PPP
Sbjct: 2474 I---------------TILPVHIL------------------------------PSPPPP 2488
Query: 161 GDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPRDSPQPGQGHSPGATA 220
+ P + + P P A + P+ P P S T
Sbjct: 2489 SQIP------PCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTN 2542
Query: 221 AATGLPPEPE--------PDSTDYSELADADILSELASLTCPEAQL-------------- 258
GL PE E P+S + + +A ++ S SL P+ L
Sbjct: 2543 LPLGLRPEAELCAQALASPESLELASVASSETSS--LSLVPPKDLLPVAVEILPVSEKNL 2600
Query: 259 ----------LEAQALEPPSPEPEPQLLDPQPRFLDPQALE-PL----GEALELPPLQPL 303
LEA ++ + P + + P+ E PL LELPP
Sbjct: 2601 SLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAAS 2660
Query: 304 ADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEP-QQPLGHCPLAEP 362
+PL P A + + L ++ + + + + P P G P P
Sbjct: 2661 DEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPP 2720
Query: 363 LRLDLCSPH------GPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPL 416
R G PG PK + R + ++ R R+ G L+P
Sbjct: 2721 RRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVP- 2779
Query: 417 PMPTGLVAALAEPPPPP------PPPPPALPGPGPVSVPELKPESSQTPVVSTRK----- 465
G+ A P P P P + GP + P Q P ++ R
Sbjct: 2780 ----GVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGV 2835
Query: 466 -GKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSSLSSSLSVEGKELGLRVSAEPTPLLKMK 524
G +A P ++ RR K + + + G V P+ LK K
Sbjct: 2836 TGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPA-------DAGRGVDEAPSSTLKGK 2888
Query: 525 NNGRN-------VVVVFP-------PGEMPI--------------ILKRKRGRPPKNLLL 556
NG + ++V P PG P+ + KR+RGRPPK L
Sbjct: 2889 TNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDL 2948
Query: 557 ------------------------GPGKPKEPAVV---AAEAATVAAATMA-MPEVKKRR 588
P P P +V A A TV T++ P +KR
Sbjct: 2949 PIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTATVANTVTTVTISTSPPKRKRG 3008
Query: 589 RRKQKLASPQPS 600
R + SP+PS
Sbjct: 3009 RPPKNPPSPRPS 3020
Score = 36.6 bits (83), Expect = 0.20
Identities = 69/268 (25%), Positives = 95/268 (35%), Gaps = 48/268 (17%)
Query: 1345 GPYSMNPS--TPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTC 1402
GP S+ PS +PS G +PSL + + G P L P + GL +P C
Sbjct: 1489 GPPSLAPSGASPSASALTLGL-ATAPSLSSSQTPGH--PLLLAPTSSHVPGLNSTVAPAC 1545
Query: 1403 SPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCK 1462
SP L L P P Q + L A++A L+ P+ P
Sbjct: 1546 SPVLVPASALASP----FPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQ------- 1594
Query: 1463 GTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMA 1522
TA P + +P +LA G +AP LAS + P+ +
Sbjct: 1595 -TAILAPSPAPPLAP-------LPVLAPSPG-------AAPVLAS-------SQTPVPVM 1632
Query: 1523 RPPGPPRGPAAAAAGYGCPL-----LSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGL 1577
P P A+A+ P S T+ P P S LP + + P P L
Sbjct: 1633 APSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLP-SPASTQTLALAPALAPTL 1691
Query: 1578 GGGPKSGFL----GPMAEPHPEDTFTVT 1601
GG S L G P P T ++T
Sbjct: 1692 GGSSPSQTLSLGTGNPQGPFPTQTLSLT 1719
Score = 35.0 bits (79), Expect = 0.58
Identities = 99/480 (20%), Positives = 166/480 (34%), Gaps = 81/480 (16%)
Query: 155 PPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKSERPSHPL----YEPEPEPRDSPQP 210
PP P P ++ + P P++ P PL P P P S QP
Sbjct: 984 PPRPKPVKMKVNRMLQPV-------PKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQP 1036
Query: 211 GQGHSPGATAAA--------------TGLPPEP------EPDSTDYSELADADILSELAS 250
G P A+ PP P +P+S ++ + L L+
Sbjct: 1037 TPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSP-LGVLSG 1095
Query: 251 LTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLG--EALELPPLQPLADPLG 308
+ P L + P+P P P L P P L+PL PP
Sbjct: 1096 TSRPPTPTLSLK----PTP-PAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTT 1150
Query: 309 LPGLALQALDTLPDSLESQLLDP--QALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLD 366
A+ + + +L P QA P +++ + Q+P+ + ++PL
Sbjct: 1151 TATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQ 1210
Query: 367 LCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRG--RKADAGPEGRLLPLPMPTGLVA 424
+ +G+ R + + R R AG + L+ P L+
Sbjct: 1211 I---------QGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQ 1261
Query: 425 ALAEPPPPPPPPPPALPGPGPVSVP-----ELKPESSQTPVVSTRKGKCRGVRRMVVKMA 479
A+A P P P P LP P + P L ++Q P GV ++VV+ A
Sbjct: 1262 AVA--PTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNN---TGVVKIVVRQA 1316
Query: 480 K-------IPVSLGRRNKTTYKVSSLSSSLS-----VEGKELGLRVSAEPT-----PLLK 522
P++ R ++ + L+ + + LG + PT PLLK
Sbjct: 1317 PRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLK 1376
Query: 523 MKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLGPGKPKEPAVVAAEAATVAAATMAMP 582
+ ++ V PG P+ + P + L GP P ++ A+ ++T+++P
Sbjct: 1377 LVHSPSPEVSASAPGAAPLTISSPLHVP--SSLPGPASSPMPIPNSSPLASPVSSTVSVP 1434
Score = 33.5 bits (75), Expect = 1.7
Identities = 25/94 (26%), Positives = 39/94 (41%), Gaps = 5/94 (5%)
Query: 1009 PASPSSAHSAGYAPPPTG---GPCLPPSKASFFSSSEGAPFSGSAPTPLRCDS--RASTV 1063
P P+S P P G G PP+ + AP S P S + TV
Sbjct: 1074 PLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTV 1133
Query: 1064 SPGGYMVPKGTTASATSAASAASSSSSSFQPSPE 1097
PG P T ++T+ A+A +++ + P+P+
Sbjct: 1134 PPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQ 1167
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 56.2 bits (134), Expect = 2e-07
Identities = 130/510 (25%), Positives = 174/510 (34%), Gaps = 122/510 (23%)
Query: 852 LLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAG----- 906
+L SA P+++ S A PP + G P A ++V GAG
Sbjct: 888 ILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVP---LAAPSMSVRGGGAGQPLPL 944
Query: 907 -ADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPS-AMARSPTTHP-- 962
+ P PV + Q PP + LTP T LVPP S A PT+ P
Sbjct: 945 VSPPFSVPVQNGAQ--PPSKIIQ--LTPVP-----VSTPSGLVPPLSPATLPGPTSQPQK 995
Query: 963 ---PANT---YLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAH 1016
P++T Y+ GG+ +P G + S A G + P+ P+
Sbjct: 996 VLLPSSTRITYVQSAGGHALPLGT-SPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQ 1054
Query: 1017 ---SAGYAP---------PPTGGPCLPPSKASFFSSSEGAPFSGS-APT---PLRCDSRA 1060
SAG AP P P LPP+ A+ A +SGS APT PL S+A
Sbjct: 1055 PLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQA 1114
Query: 1061 ----------STVSPGGYMVPKGTTASATSAASAASSSSSSFQPSPENCRQFAGASQWPF 1110
ST P ++PKG A AT+ P+P + PF
Sbjct: 1115 PPSLVYTVATSTTPPAATILPKGPPAPATAT------------PAPTS----------PF 1152
Query: 1111 RQGYGGLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVSETFSESSSDS 1170
G S + PS PQKVK A S + S
Sbjct: 1153 PSATAGSMTYSLVAPKAQRPS---------------PKAPQKVKAAIASIPVGSFEAGAS 1197
Query: 1171 TQFN----QPVGGGGFRRANSEASSSEGQSSLSSLEKLMMDWN--------------EAS 1212
+ QP+ G R + S EGQ + + L W E +
Sbjct: 1198 GRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERT 1257
Query: 1213 SAPGYNWNQSVLFQSSSK---PGRGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPR 1269
SA G S SSS PG+G + + PT S A + P+ G
Sbjct: 1258 SAKGPETMASKFPSSSSDWRVPGQGLENRGEP--------PTPPSPAPA--PAVAPGGSS 1307
Query: 1270 QPRGGRGGGACSAKKERGGAAAKAKFIPKP 1299
+ GR G +KE G K K P P
Sbjct: 1308 ESSSGRAAGDTPERKEAAGTGKKVKVRPPP 1337
Score = 42.7 bits (99), Expect = 0.003
Identities = 199/908 (21%), Positives = 282/908 (31%), Gaps = 181/908 (19%)
Query: 712 VGGPGLTELGHPRKRGRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGD 771
VGGPG PR V ++ G + ++ Q+ SGP A ++G
Sbjct: 344 VGGPGSAR---PRAFSHSGVHSLDGGEVDSQALQEL-----TQMVSGP------ASYSGP 389
Query: 772 KGGGWAPHHGHPGGQAGRNCGFQGTEARAFASTGLESGASGRGSYYSTGAPSGQTELSQE 831
K + +G PG A E A A+TG R S A T +E
Sbjct: 390 KP---STQYGAPGPFAAPG------EGGALAATGRPPLLPTRASRSQRAASEDMTS-DEE 439
Query: 832 RQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPSR 891
R + + +DD D L + SG +G +G
Sbjct: 440 RMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEG---NKGF------ 490
Query: 892 GAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPP 951
G K + SS P P P YG P++S P
Sbjct: 491 GRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASS----------PA 540
Query: 952 SAMARSPTTHP-PANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPA 1010
S+ A + T+ + T+ Q G G+ P P G SK F LP
Sbjct: 541 SSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRF-------LPM 593
Query: 1011 SPSS-----AHSAG---------YAPPPTGGP------CLPPSKASFFSSSEGAPFSGSA 1050
P++ S G A PP+GG LPP+K P SA
Sbjct: 594 DPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVP---SA 650
Query: 1051 PTP-LRCDSRASTVS-PGGYMVP---KGTTASATSAASAASSSSSSFQPSPENCR----Q 1101
P P L + A+ +S P MV + +++ AS +S + SP + +
Sbjct: 651 PAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTE 710
Query: 1102 FAGASQWPFRQGYG-GLDWASEAFSQLYNPSFDCHVSEPNVILDISNYTPQKVKQQTAVS 1160
S+ P G L ++ + + +P+ V+ P +L P V +
Sbjct: 711 MGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHL-VAGP--LLGTVGKAPATVTNLLVGT 767
Query: 1161 ETFSESSSDSTQFNQPVGGGGFRRANSEASSSEG------------------------QS 1196
+ + + QF GG A S A + G Q
Sbjct: 768 PGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQY 827
Query: 1197 SLSSLEKLMMDWNEASSAPGYNWNQ------SVLFQSSSKPGRGRRKKVDLFEASHLGFP 1250
L +L + + + APG + + + PG KV A G P
Sbjct: 828 ILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIP 887
Query: 1251 TSASAAASGYPSKRSTGPRQ--PRGGRGGG---------ACSAKKERGGAAAKAKFIPKP 1299
S ++ P +S P Q P GG A + RGG A + P
Sbjct: 888 ILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQ------P 941
Query: 1300 QP-VNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPST--PSD 1356
P V+P F G S ++P+P + + V P GP S PS
Sbjct: 942 LPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPS- 1000
Query: 1357 GTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPP 1416
S + + G H PL P AG +Y PT S LGF
Sbjct: 1001 ----------STRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGF-------- 1042
Query: 1417 TKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARS 1476
T L P A Q LS PL P S P + +
Sbjct: 1043 TSLGPSGP-------------AFVQPLLSAGQAPLLAPGQVGVS---------PVPSPQL 1080
Query: 1477 PPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGP---PRGPAA 1533
PP G ++ F + A SAP A P PP P+GP A
Sbjct: 1081 PPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPA 1140
Query: 1534 AAAGYGCP 1541
A P
Sbjct: 1141 PATATPAP 1148
Score = 35.4 bits (80), Expect = 0.45
Identities = 59/280 (21%), Positives = 80/280 (28%), Gaps = 43/280 (15%)
Query: 208 PQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPP 267
P G +P G+ P P P + P ++ A P
Sbjct: 1055 PLLSAGQAPLLAPGQVGVSPVPSPQLPP--------------ACAAPGGPVITAFYSGSP 1100
Query: 268 SPEPEPQLLDPQ---PRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSL 324
+P L P P + A A + P P A P S+
Sbjct: 1101 APTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSM 1160
Query: 325 ESQLLDPQALDPLPK--------LLDVPGRRLE----------PQQPLGHCPLAEPLRLD 366
L+ P+A P PK + +P E P+QPL P+ EP +
Sbjct: 1161 TYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPE 1220
Query: 367 LCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLP-------MP 419
G P P P T + R + GPE P +P
Sbjct: 1221 -SELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVP 1279
Query: 420 TGLVAALAEPPPPPPPPPPALPGPGPVSVPELKPESSQTP 459
+ EPP PP P P PG S + TP
Sbjct: 1280 GQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTP 1319
Score = 35.4 bits (80), Expect = 0.45
Identities = 41/149 (27%), Positives = 53/149 (35%), Gaps = 29/149 (19%)
Query: 153 SRPPAPPPGDLQYSFFSSPSLANSI-RSPEERATPHAKSERPSHPLYEPEPEPRDSPQPG 211
S PP PPP + + S ++A+ S + P E P P P P + PG
Sbjct: 1245 SSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPG 1304
Query: 212 QGHSPGATAAATGLPPE--------------PEP-----DSTDYSELADADILSELASLT 252
G S ++ A G PE P P DS D L++ D A L
Sbjct: 1305 -GSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAEL- 1362
Query: 253 CPEAQLLEAQALEPPSPEPEPQLLDPQPR 281
PE + E P P Q L PR
Sbjct: 1363 -PEFR------PEEVLPSPTLQSLATSPR 1384
Score = 34.7 bits (78), Expect = 0.76
Identities = 86/385 (22%), Positives = 128/385 (33%), Gaps = 71/385 (18%)
Query: 210 PGQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQL--LEAQALEPP 267
PG G + G+ A A P P P + L + +T + L L Q P
Sbjct: 786 PGGGTTAGSGAGAGSGPNGPVPLG-----ILQPGALGKAGGITQVQYILPTLPQQLQVAP 840
Query: 268 SPEPEPQLLDPQP---------RFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALD 318
+P P P P RF P G+ L P G+P LQ++
Sbjct: 841 APAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTP-----GIP--ILQSVP 893
Query: 319 TLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPPGPEG 378
+ P + QA P +PG+ L PLA P G P P
Sbjct: 894 SAPPPKAQSVSPVQAPPPGGSAQLLPGKVL--------VPLAAPSMSVRGGGAGQPLPLV 945
Query: 379 HPKYALRRTDRPKILCRRRKAGRGRKADAGPEGRLLPL-PMPTGLVAALAEPPPPPPPPP 437
P +++ + A P +++ L P+P + L PP P
Sbjct: 946 SPPFSVPVQN-----------------GAQPPSKIIQLTPVPVSTPSGLV-----PPLSP 983
Query: 438 PALPGPGPVSVPELKPESSQTPVVSTRKGKCRGVRRMVVKMAKIPVSLGRRNKTTYKVSS 497
LPGP L P S++ V + G + + P S T+Y
Sbjct: 984 ATLPGPTSQPQKVLLPSSTRITYVQSAGGH-------ALPLGTSPASSQAGTVTSY---G 1033
Query: 498 LSSSLSVEGKELGLRVSAEPTPLLKMKNNGRNVVVVFPPGEMPIILKRKRGRPPKNLLLG 557
+SS+++ LG A PLL + PG++ + PP
Sbjct: 1034 PTSSVALGFTSLGPSGPAFVQPLL-----SAGQAPLLAPGQVGVSPVPSPQLPP--ACAA 1086
Query: 558 PGKPKEPAVVAAEAATVAAATMAMP 582
PG P A + A ++A +A P
Sbjct: 1087 PGGPVITAFYSGSPAPTSSAPLAQP 1111
Score = 33.1 bits (74), Expect = 2.2
Identities = 36/119 (30%), Positives = 44/119 (36%), Gaps = 23/119 (19%)
Query: 156 PAPPPGDLQYSFFSSPSLANSIRSPEERA----------TPHAKSERPSHPLYEPEPEPR 205
P+ P + Q S P +N + P E A T A ERP P P
Sbjct: 51 PSVQPSEAQQPA-SHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGP- 108
Query: 206 DSPQP------GQGHSPGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQL 258
P P G+G P A+G P EP DS S+ DA S+ PE QL
Sbjct: 109 GPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDA-----FLSIMSPEIQL 162
Score = 32.3 bits (72), Expect = 3.8
Identities = 22/62 (35%), Positives = 25/62 (40%), Gaps = 22/62 (35%)
Query: 414 LPLPMPTGLVAALAEPP---------------------PPPPPPPPALPG-PGPVSVPEL 451
LP+P PTG AA A P PP PPPP + PG PG P+
Sbjct: 1535 LPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQP 1594
Query: 452 KP 453
P
Sbjct: 1595 SP 1596
Score = 31.6 bits (70), Expect = 6.5
Identities = 62/259 (23%), Positives = 83/259 (32%), Gaps = 50/259 (19%)
Query: 828 LSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLAT 887
L+ + + Y + +S D + S R R++S + + + + T
Sbjct: 1379 LATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFT 1438
Query: 888 FPSRGAKASPVAVGSSGAGADPSFQPVLSARQTFPPGRAA------SYGLTP-----AAS 936
F G +A V + P S R+T RA +G P AA
Sbjct: 1439 FDRTGTEAEDVL-----GELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAF 1493
Query: 937 DCRAAETFP---------KLVPPPSAMARSPTTHPPANTYLPQYGGYGAGQSVFAPTKPF 987
R A+ FP + V A +PT PP G P P
Sbjct: 1494 QARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPP-------------GAEAPLPVPPP 1540
Query: 988 TGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSSEGAPFS 1047
TG A + S A G P SPSS A PP LPP S G P
Sbjct: 1541 TGTAAAPAPTPSPAGGPD---PTSPSSDSGTAQAAPP-----LPPPP----ESGPGQPGW 1588
Query: 1048 GSAPTPLRCDSRASTVSPG 1066
AP P ST + G
Sbjct: 1589 EGAPQPSPPPPGPSTAATG 1607
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 56.2 bits (134), Expect = 2e-07
Identities = 90/352 (25%), Positives = 116/352 (32%), Gaps = 78/352 (22%)
Query: 136 QDLQHSGVHLDCG----GLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHA--- 188
+ L S VH G G L + P PPP Q + + TPH
Sbjct: 740 EGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQST----------------QPTPHGLLL 783
Query: 189 KSERPSHPLYEPEPEPRDSPQP-GQGHSPGATAAATGL--------------PPEPEPDS 233
++ P PL P P P+ P SP +A+ G+ PP P P
Sbjct: 784 EAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP 843
Query: 234 TDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGE 293
+A L + LEP +P P L P+ P A++ L
Sbjct: 844 PPMPLQLEAH---------------LRSHGLEPAAPSPR---LRPEESLDPPGAMQELLG 885
Query: 294 ALELPPLQPLADPLGLPGLALQALDTLPDSLESQLLDPQALDPLPKLLDVPGRRLEPQQP 353
ALE P P +G P + S Q PL + P L+ ++
Sbjct: 886 ALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTSIC-FPDSLLQDEE- 943
Query: 354 LGHCPLAEPL----RLDLCSPHGPPGPEGHPKYALRRTDRPKILCRRRKAGRGRKADAGP 409
P E + D GPP EG PK P GR + AGP
Sbjct: 944 RSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGP 1003
Query: 410 EGRLLPL-------------PMPTGLVAA---LAEPPPPPPPPPPALPGPGP 445
E L L P GL+ + A PPPPPPPPPP P P
Sbjct: 1004 ETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASEP 1055
Score = 52.4 bits (124), Expect = 4e-06
Identities = 106/436 (24%), Positives = 137/436 (31%), Gaps = 118/436 (27%)
Query: 61 PRPPPRRDPSTRRPPVLAKGDDPLPPRAARPVSQARCPTPVGDGSSS------------- 107
P P P R P AK D P PR + PT G S+S
Sbjct: 1145 PNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRG 1204
Query: 108 ----RRCWDNGRVNLRPVVQLIDIMKDLTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDL 163
R+ + G L P+ L ++LS P A
Sbjct: 1205 RGRGRKAEEAGGTRLEPLKPL------------------------KIKLSVPKAGEGLGT 1240
Query: 164 QYSFFSSPSLANSIRSPEERATPHAKSERPSHPLYEPEPEPR--------DSPQPGQGHS 215
S + NS+ S R AK + + E +PE + D + G+ H
Sbjct: 1241 SSGDAISGTDHNSLDSSLTREKIEAKIKE----VEEKQPEMKSGFMASFLDFLKSGKRHP 1296
Query: 216 PGATAAATGLPPEPEPDSTDYSELADADILSELASLTCPEAQLLEAQALEPPSPEPEPQL 275
P A T PP P S S + A+ L+P P P +
Sbjct: 1297 PLYQAGLT--PPLSPPKSVPPS---------------------VPARGLQP-QPPATPAV 1332
Query: 276 LDPQPRFLDPQALEPLGEALELPPLQPLADPLGLPGLALQALDTLPDSLES-QLLDPQAL 334
P P LG ALE + L LG P + + L +LE+
Sbjct: 1333 PHPPP-----SGAFGLGGALEAAESEGLG--LGCPSPCKRLDEELKRNLETLPSFSSDEE 1385
Query: 335 DPLPKLLDVPGRRLEPQQPLGHCPLAEPLRLDLCSPHGPP--------GPE---GHPKYA 383
D + K D+ L PLA P D +P GPP GP G P
Sbjct: 1386 DSVAKNRDLQESISSAISALDDPPLAGPK--DTSTPDGPPLAPAAAVPGPPPLPGLPSAN 1443
Query: 384 LRRTDRPKILCRRRKAGRGRKADAGPEGRLLPLPMPTGLVAALAEPPPPPPPPPPALPGP 443
T P +L + P P P +PPPPPPPP PALP P
Sbjct: 1444 SNGTPEPPLLEEK------------------PPPTPPPAPTPQPQPPPPPPPPQPALPSP 1485
Query: 444 GPVSVPELKPESSQTP 459
P+ P P S P
Sbjct: 1486 PPLVAP--TPSSPPPP 1499
Score = 45.8 bits (107), Expect = 3e-04
Identities = 54/195 (27%), Positives = 79/195 (40%), Gaps = 35/195 (17%)
Query: 872 AGPPTSALPAQRGLATFPSRGAKASPVAVGSSGAGADPS-FQPVLSARQTFPPGRAASYG 930
AG P+ A P+ AT + G P A G GAG ++P++ + PG G
Sbjct: 343 AGEPSKAGPSG---ATAGASGRATGPEAAGGGGAGGGGGGYRPIIQS-----PGYKTGKG 394
Query: 931 LTPAASDCRAAETFPKLVPPPSAMA--RSPTTHPPANTYLP--QYGGYGAGQSVFAPTKP 986
AA+ T P PPP + A + + PA Y G GAG ++P +P
Sbjct: 395 GYGAAA---GGATRP---PPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQP 448
Query: 987 FTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPPTGGPCLPPSKASFFSSS----- 1041
Q + +G G + S + ++S G PP+G P PP A+ S S
Sbjct: 449 ---QGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPP--PPGLATCQSYSPDQLQ 503
Query: 1042 ------EGAPFSGSA 1050
+G P+ G A
Sbjct: 504 GQLYGVQGEPYPGPA 518
Score = 44.7 bits (104), Expect = 7e-04
Identities = 79/326 (24%), Positives = 103/326 (31%), Gaps = 57/326 (17%)
Query: 12 SSAVCSSPDYLREPKYYPGGPPTPRPLLPTRPPASPPDKAFSTHAFSENPRPPPRRDPST 71
S + S D+L+ K +P P PP SPP K+ + +P P P+
Sbjct: 1279 SGFMASFLDFLKSGKRHP-----PLYQAGLTPPLSPP-KSVPPSVPARGLQPQPPATPAV 1332
Query: 72 RRPPVL-AKGDDPLPPRAARPVSQARCPTPVGDGSSSRRCWDNGRVNLRPVVQLIDIMKD 130
PP A G A CP+P +R + + NL + +D
Sbjct: 1333 PHPPPSGAFGLGGALEAAESEGLGLGCPSPC------KRLDEELKRNLETLPSFSSDEED 1386
Query: 131 LTRLSQDLQHSGVHLDCGGLRLSRPPAPPPGDLQYSFFSSPSLANSIRSPEERATPHAKS 190
++DLQ S + L PP P D S P LA + P P S
Sbjct: 1387 SVAKNRDLQES---ISSAISALDDPPLAGPKDT--STPDGPPLAPAAAVPGPPPLPGLPS 1441
Query: 191 ER----PSHPLYEPEPEPRDSPQPGQGHSPGATAAATGLPPEPEPDSTDYSELADADILS 246
P PL E +P P P P P PP P+P
Sbjct: 1442 ANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPP------PPPPQP--------------- 1480
Query: 247 ELASLTCPEAQLLEAQALEPPSPEPEPQLLDPQPRFLDPQALEPLGEALELPPLQPLADP 306
+L P + + PP P P P P P P P P PLA P
Sbjct: 1481 ---ALPSPPPLVAPTPSSPPPPPLPPP----PPPAMPSPPPPPP-------PAAAPLAAP 1526
Query: 307 LGLPGLALQALDTLPDSLESQLLDPQ 332
P LPD+ L Q
Sbjct: 1527 PEEPAAPSPEDPELPDTRPLHLAKKQ 1552
Score = 40.0 bits (92), Expect = 0.018
Identities = 86/323 (26%), Positives = 104/323 (32%), Gaps = 85/323 (26%)
Query: 1250 PTSASAAASGYPSKRSTGPRQPRGGRGGGACSA----------KKERGGAAAKAKFIPKP 1299
P+ A+A ASG R+TGP GG GG K +GG A A +P
Sbjct: 351 PSGATAGASG----RATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRP 406
Query: 1300 QP----VNPLFQDSPDLGLDYYSGDSS---------MSPLPSQ--------SRAFGVGER 1338
P P Q Y +G +S SP Q + FG G+
Sbjct: 407 PPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQA 466
Query: 1339 DPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHP---PTVFDAGLQ 1395
YS P P G G S +L G+ + P P GL
Sbjct: 467 QDLSKAPSYSGGPPQPPSGPPPPGL-ATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGL- 524
Query: 1396 KAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPH 1455
PT SP+L + P A G +SLG A R L
Sbjct: 525 ----PTASPSLSYSTGHSP------ALSGHGGGWGPSSLGGGGEASPSHIIRPL------ 568
Query: 1456 YDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPA----- 1510
SP G PPG SP GK + +LA SAP LA P A
Sbjct: 569 -QSPPATGR----PPG--VGSPGAPGKYLSSVLA-----------SAPFLAPPGAGSYAA 610
Query: 1511 -----TPKADKEPLEMARPPGPP 1528
K D L +A P GPP
Sbjct: 611 GAGGYKGKGDGSEL-LAGPGGPP 632
Score = 38.5 bits (88), Expect = 0.053
Identities = 101/384 (26%), Positives = 130/384 (33%), Gaps = 59/384 (15%)
Query: 1247 LGFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGA------AAKAKFIPKPQ 1300
L PT+A A++ P + G ++PR GRG G +E GG K K + P+
Sbjct: 1179 LEVPTTAGPASASTP---TDGAKKPR-GRGRGRGRKAEEAGGTRLEPLKPLKIK-LSVPK 1233
Query: 1301 PVNPLFQDSPDL--GLDYYSGDSSMSPLPSQSRAFGVGERDP----------CDFIGPYS 1348
L S D G D+ S DSS++ +++ V E+ P DF+
Sbjct: 1234 AGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGK 1293
Query: 1349 MNPSTPSDGTFGQGFHCDS--PSLGAPELDGK--HFPPLAHPPTVFDAGLQKAYSPTCSP 1404
+P G S PS+ A L + P + HPP GL A S
Sbjct: 1294 RHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESE 1353
Query: 1405 TLGFKEELRPPPTKLAACEPLKHGLQGA---------SLGHAAAAQAHLSCRDLPLGQPH 1455
LG P P K E LK L+ S+ Q +S L P
Sbjct: 1354 GLGLG---CPSPCK-RLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPP 1409
Query: 1456 YDSPSCKGTAYWYPPGSAAR---SPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATP 1512
P T P AA PP G A+ G E L PP TP
Sbjct: 1410 LAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPS----ANSNGTPEPPLLE----EKPPPTP 1461
Query: 1513 KADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQ 1572
P PP PP PA + PL++ SP P P P P
Sbjct: 1462 PPAPTPQPQPPPPPPPPQPALPSPP---PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP 1518
Query: 1573 AHPGLGGGPKSGFLGPMAEPHPED 1596
A L P+ A P PED
Sbjct: 1519 AAAPLAAPPEE-----PAAPSPED 1537
Score = 38.1 bits (87), Expect = 0.069
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 11/43 (25%)
Query: 428 EPPPPPPPPPPALP----------GPGPVS-VPELKPESSQTP 459
+PPPPPPPPPP +P G P + P L+PE S P
Sbjct: 834 QPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDP 876
Score = 37.4 bits (85), Expect = 0.12
Identities = 87/339 (25%), Positives = 108/339 (31%), Gaps = 82/339 (24%)
Query: 727 GRGEVDAVTGKPKRKRRSRKNGTLFPEQVPSGPGFGEAGAEWAGDKGGGWAPHHGHPGGQ 786
G GE G+P + S T +GP AG AG GGG+ P PG +
Sbjct: 335 GGGEPSPGAGEPSKAGPS--GATAGASGRATGPE--AAGGGGAGGGGGGYRPIIQSPGYK 390
Query: 787 AGRN----------------------CGFQGTEARAFASTGLESGASGRGSY-YSTGAPS 823
G+ C G A A+A TG SGA G G YS G P
Sbjct: 391 TGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYA-TGKASGAGGAGGQAYSPGQPQ 449
Query: 824 GQTELSQERQNLFTGYFRSLLDSDDSSDLLDFALSASRPESRKASGTYAGPP-TSALPAQ 882
G Q G + L KA GPP + P
Sbjct: 450 GLLGPQAYGQGFGGGQAQDL---------------------SKAPSYSGGPPQPPSGPPP 488
Query: 883 RGLATFPS----------RGAKASPVAVGSSGAGADPSFQPVLSARQTFPP---GRAASY 929
GLAT S G + P ++ + P+ P LS P G +
Sbjct: 489 PGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGW 548
Query: 930 GLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPANTYLPQYGGYGAG----QSVFAPTK 985
G + A+ PS + R P PPA P G GA SV A +
Sbjct: 549 GPSSLGGGGEAS---------PSHIIR-PLQSPPATGRPPGVGSPGAPGKYLSSVLA-SA 597
Query: 986 PFTGQDCANSKDCSFAYGSGNSLPASPSSAHSAGYAPPP 1024
PF A S+A G+G S AG PP
Sbjct: 598 PFLAPPGAG----SYAAGAGGYKGKGDGSELLAGPGGPP 632
Score = 33.9 bits (76), Expect = 1.3
Identities = 50/180 (27%), Positives = 61/180 (33%), Gaps = 41/180 (22%)
Query: 905 AGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPPPSAMARSPTTHPPA 964
+G SF L + + PP A GLTP S PK VPP S AR PPA
Sbjct: 1279 SGFMASFLDFLKSGKRHPPLYQA--GLTPPLSP-------PKSVPP-SVPARGLQPQPPA 1328
Query: 965 NTYLPQ---YGGYGAGQSVFAPTKPFTGQDCAN-------------------SKDCSFAY 1002
+P G +G G ++ A G C + S D +
Sbjct: 1329 TPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSV 1388
Query: 1003 GSGNSLPASPSSAHSAGYAPP---------PTGGPCLPPSKASFFSSSEGAPFSGSAPTP 1053
L S SSA SA PP P G P P + G P + S TP
Sbjct: 1389 AKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTP 1448
Score = 32.3 bits (72), Expect = 3.8
Identities = 53/198 (26%), Positives = 67/198 (33%), Gaps = 22/198 (11%)
Query: 845 DSDDSSDLLDFALSASRPESRKASGTYAGPPTSALPAQRGLATFPS-RGAKASPVAVGSS 903
+S D + L A P T GPP S G PS +G KA +S
Sbjct: 872 ESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVPLTS 931
Query: 904 GAGADPSFQPVLSARQTFPPGRAASYGLTPAASDCRAAETFPKLVPP-----PSAMARSP 958
D Q ++F P +G AA+ + K PP P A A P
Sbjct: 932 ICFPDSLLQ---DEERSFFPTMEEMFG-------GGAADDYGKAGPPEDEGDPKAGAGPP 981
Query: 959 TTHPPANTYLPQYGGYGAGQSVFAPTKPFTGQDCANSKDCSFAYGSGNSLPASPSSAHSA 1018
P + Y P G +G P P G D + + L S H A
Sbjct: 982 PGPPAYDPYGPYCPGRASGAG---PETPGLGLDPNKPPELPSTVNA-EPLGLIQSGPHQA 1037
Query: 1019 GYAPPPTGGPCLPPSKAS 1036
APPP P PP+ AS
Sbjct: 1038 --APPPPPPPPPPPAPAS 1053
Score = 32.0 bits (71), Expect = 4.9
Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 25/95 (26%)
Query: 1450 PLGQPHYD--SPSCKGTAYWYPP-----GSAARSPPYEGKVGTGLLADFLGRTEAACLSA 1502
P G P YD P C G A P G PP ++ + + A+ LG + S
Sbjct: 981 PPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPP---ELPSTVNAEPLGLIQ----SG 1033
Query: 1503 PHLASPPATPKADKEPLEMARPPGPPRGPAAAAAG 1537
PH A+PP P PP PP PA+ G
Sbjct: 1034 PHQAAPPPPP-----------PPPPPPAPASEPKG 1057
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 88,426,561
Number of Sequences: 37866
Number of extensions: 6027123
Number of successful extensions: 65797
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 526
Number of HSP's successfully gapped in prelim test: 1328
Number of HSP's that attempted gapping in prelim test: 31697
Number of HSP's gapped (non-prelim): 23238
length of query: 1603
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1487
effective length of database: 13,855,062
effective search space: 20602477194
effective search space used: 20602477194
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.