Search of human proteins with 71143104

Search of human proteins with 71143104

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71143104 potassium channel tetramerisation domain containing
21 [Homo sapiens]
         (260 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71143104 potassium channel tetramerisation domain containing ...   520   e-148
gi|51036594 potassium channel tetramerisation domain containing ...   153   2e-37
gi|189571693 potassium channel tetramerisation domain containing...   150   1e-36
gi|189571691 potassium channel tetramerisation domain containing...   150   1e-36
gi|194018443 potassium channel tetramerisation domain containing...   106   2e-23
gi|194018441 potassium channel tetramerisation domain containing...   106   2e-23
gi|194018439 potassium channel tetramerisation domain containing...   106   2e-23
gi|218505694 potassium channel tetramerisation domain containing...   102   4e-22
gi|209969708 potassium channel tetramerisation domain containing...   102   4e-22
gi|40217617 potassium channel tetramerisation domain containing ...   102   4e-22
gi|146198864 potassium channel tetramerisation domain containing...    96   2e-20
gi|55926200 potassium channel tetramerisation domain containing ...    92   3e-19
gi|19923973 potassium channel tetramerisation domain containing ...    88   7e-18
gi|38198663 potassium channel tetramerisation domain containing ...    88   9e-18
gi|30578412 potassium channel tetramerisation domain containing ...    86   4e-17
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       84   1e-16
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       84   1e-16
gi|13994353 potassium channel tetramerisation domain containing ...    84   1e-16
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  83   2e-16
gi|45387953 potassium channel tetramerization domain containing ...    82   5e-16
gi|23308551 potassium channel tetramerisation domain containing ...    80   2e-15
gi|46255026 potassium channel tetramerisation domain containing ...    80   2e-15
gi|142356950 potassium channel tetramerisation domain containing...    79   5e-15
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    78   7e-15
gi|39753959 potassium channel tetramerisation domain containing ...    64   1e-10
gi|169234778 potassium channel tetramerisation domain containing...    64   2e-10
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    57   1e-08
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    57   1e-08
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...    57   1e-08
gi|9506651 potassium channel tetramerisation domain containing 5...    55   5e-08

>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score =  520 bits (1339), Expect = e-148
 Identities = 260/260 (100%), Positives = 260/260 (100%)

Query: 1   MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 60
           MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL
Sbjct: 1   MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 60

Query: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRV 120
           NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRV
Sbjct: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRV 120

Query: 121 QTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQD 180
           QTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQD
Sbjct: 121 QTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQD 180

Query: 181 PNHLTLDWVANVEGLPEEEYTKQNLKRLWVVPANKQINSFQVFVEEVLKIALSDGFCIDS 240
           PNHLTLDWVANVEGLPEEEYTKQNLKRLWVVPANKQINSFQVFVEEVLKIALSDGFCIDS
Sbjct: 181 PNHLTLDWVANVEGLPEEEYTKQNLKRLWVVPANKQINSFQVFVEEVLKIALSDGFCIDS 240

Query: 241 SHPHALDFMNNKIIRLIRYR 260
           SHPHALDFMNNKIIRLIRYR
Sbjct: 241 SHPHALDFMNNKIIRLIRYR 260


>gi|51036594 potassium channel tetramerisation domain containing 11
           [Homo sapiens]
          Length = 232

 Score =  153 bits (386), Expect = 2e-37
 Identities = 93/239 (38%), Positives = 132/239 (55%), Gaps = 14/239 (5%)

Query: 28  MLGAMFSG--KMPTKRDSQG--NCFIDRDGKVFRYILNFLRTSHLDLPEDFQEMGLLRRE 83
           MLGAMF     MP   +SQG  + FIDRDGK FR+ILNFLR   LDLP  + E  LLR E
Sbjct: 1   MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAE 60

Query: 84  ADFYQVQPLIEALQEKEV-ELSKAEKNAMLNITLNQRVQTVHFTVREAPQIYSLSSSSME 142
           ADFYQ++PL++AL+E E  + + A   A+L+  ++   + VHF+ R  P  Y LSS  ++
Sbjct: 61  ADFYQIRPLLDALRELEASQGTPAPTAALLHADVDVSPRLVHFSARRGPHHYELSSVQVD 120

Query: 143 VFNANIFSTSCLFLKLLGSKLFYCSNGNLSSITSHLQDPNHLTLDWVANVEGLPEEEYTK 202
            F AN+F T    L  L ++    S           +   H  L+W      LPE EY +
Sbjct: 121 TFRANLFCTDSECLGALRARFGVASG-------DRAEGSPHFHLEWAPRPVELPEVEYGR 173

Query: 203 QNLKRLWV--VPANKQINSFQVFVEEVLKIALSDGFCIDSSHPHALDFMNNKIIRLIRY 259
             L+ LW       +++     F+EEVL++AL  GF +DS  P   D +N++ +R +R+
Sbjct: 174 LGLQPLWTGGPGERREVVGTPSFLEEVLRVALEHGFRLDSVFPDPEDLLNSRSLRFVRH 232


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score =  150 bits (379), Expect = 1e-36
 Identities = 76/119 (63%), Positives = 87/119 (73%), Gaps = 11/119 (9%)

Query: 1   MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 60
           M+DP+TLNVGG LYTTSL TLT +PDSMLGAMF G  PT RD QGN FIDRDG +FRY+L
Sbjct: 10  MTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVL 69

Query: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ-----------EKEVELSKAEK 108
           NFLRTS L LP DF+E  LLR+EADFYQ++PLI+ L            E+ VELS   K
Sbjct: 70  NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRK 128


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score =  150 bits (379), Expect = 1e-36
 Identities = 76/119 (63%), Positives = 87/119 (73%), Gaps = 11/119 (9%)

Query: 1   MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 60
           M+DP+TLNVGG LYTTSL TLT +PDSMLGAMF G  PT RD QGN FIDRDG +FRY+L
Sbjct: 10  MTDPVTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVL 69

Query: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ-----------EKEVELSKAEK 108
           NFLRTS L LP DF+E  LLR+EADFYQ++PLI+ L            E+ VELS   K
Sbjct: 70  NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSSTRK 128


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score =  106 bits (265), Expect = 2e-23
 Identities = 50/107 (46%), Positives = 77/107 (71%), Gaps = 1/107 (0%)

Query: 4   PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
           P+ ++VGG +YT+SLATLT +PDS +  +F+G  P   DS + + FIDRDG++FRY+L+F
Sbjct: 57  PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116

Query: 63  LRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKN 109
           LRTS L LP+DF++  LL  EA +YQ+QP++  L+  + E  +  ++
Sbjct: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRS 163


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score =  106 bits (265), Expect = 2e-23
 Identities = 50/107 (46%), Positives = 77/107 (71%), Gaps = 1/107 (0%)

Query: 4   PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
           P+ ++VGG +YT+SLATLT +PDS +  +F+G  P   DS + + FIDRDG++FRY+L+F
Sbjct: 57  PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116

Query: 63  LRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKN 109
           LRTS L LP+DF++  LL  EA +YQ+QP++  L+  + E  +  ++
Sbjct: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRS 163


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score =  106 bits (265), Expect = 2e-23
 Identities = 50/107 (46%), Positives = 77/107 (71%), Gaps = 1/107 (0%)

Query: 4   PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
           P+ ++VGG +YT+SLATLT +PDS +  +F+G  P   DS + + FIDRDG++FRY+L+F
Sbjct: 57  PVHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSF 116

Query: 63  LRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKN 109
           LRTS L LP+DF++  LL  EA +YQ+QP++  L+  + E  +  ++
Sbjct: 117 LRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQRRRS 163


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score =  102 bits (253), Expect = 4e-22
 Identities = 48/91 (52%), Positives = 70/91 (76%), Gaps = 1/91 (1%)

Query: 4   PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
           P+ ++VGG +YT+SLATLT +P+S +G +F G  P   DS + + FIDRDG++FRYILNF
Sbjct: 639 PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 698

Query: 63  LRTSHLDLPEDFQEMGLLRREADFYQVQPLI 93
           LRTS L +P+DF++  LL  EA ++Q+QP++
Sbjct: 699 LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 729


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score =  102 bits (253), Expect = 4e-22
 Identities = 48/91 (52%), Positives = 70/91 (76%), Gaps = 1/91 (1%)

Query: 4   PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
           P+ ++VGG +YT+SLATLT +P+S +G +F G  P   DS + + FIDRDG++FRYILNF
Sbjct: 31  PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 90

Query: 63  LRTSHLDLPEDFQEMGLLRREADFYQVQPLI 93
           LRTS L +P+DF++  LL  EA ++Q+QP++
Sbjct: 91  LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score =  102 bits (253), Expect = 4e-22
 Identities = 48/91 (52%), Positives = 70/91 (76%), Gaps = 1/91 (1%)

Query: 4   PITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDS-QGNCFIDRDGKVFRYILNF 62
           P+ ++VGG +YT+SLATLT +P+S +G +F G  P   DS + + FIDRDG++FRYILNF
Sbjct: 31  PVHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNF 90

Query: 63  LRTSHLDLPEDFQEMGLLRREADFYQVQPLI 93
           LRTS L +P+DF++  LL  EA ++Q+QP++
Sbjct: 91  LRTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 52/114 (45%), Positives = 73/114 (64%), Gaps = 1/114 (0%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
           +TLNVGG LY T   TLT +PD+ L  + +GK+    D+ G+ FIDRDG +FR++LNFLR
Sbjct: 35  MTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFLR 94

Query: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEK-EVELSKAEKNAMLNITLN 117
              L LPE F+E  LL +EA+F+Q++ L E ++ + E E     +   L IT N
Sbjct: 95  NGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSRWEKEQLTPRETTFLEITDN 148


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 92.4 bits (228), Expect = 3e-19
 Identities = 49/107 (45%), Positives = 70/107 (65%), Gaps = 4/107 (3%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTK----RDSQGNCFIDRDGKVFRYIL 60
           + LNVGG++Y T  +TL S P S+L  MFS K  T     +DS+G  FIDRDG +FRYIL
Sbjct: 27  VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86

Query: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAE 107
           ++LR   + LP+ F E G L+REA+++Q+  L++ L   E++ S  E
Sbjct: 87  DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDE 133


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 88.2 bits (217), Expect = 7e-18
 Identities = 44/96 (45%), Positives = 65/96 (67%), Gaps = 2/96 (2%)

Query: 3   DPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTK--RDSQGNCFIDRDGKVFRYIL 60
           D + LNVGG++Y T   T+ S PDS+L  MF+ + P +  RDS+G  F+DRDG +FRYIL
Sbjct: 34  DIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYIL 93

Query: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEAL 96
           ++LR   L LP+ F E   L+REA+++++  L+  L
Sbjct: 94  DYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRL 129


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 87.8 bits (216), Expect = 9e-18
 Identities = 47/104 (45%), Positives = 63/104 (60%), Gaps = 9/104 (8%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPT---------KRDSQGNCFIDRDGKV 55
           + LNVGG++Y T  +TL S PDS L +MFS   P           RDS+   FIDRDG +
Sbjct: 46  VELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFL 105

Query: 56  FRYILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEK 99
           FRY+L++LR   L LPE F E   L REA+++Q+  L++ L  K
Sbjct: 106 FRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPK 149


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 85.5 bits (210), Expect = 4e-17
 Identities = 67/174 (38%), Positives = 90/174 (51%), Gaps = 18/174 (10%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
           + LNVGG L+ T+L TLT   D+ML AMFSG++    D+ G   IDR G+ F  ILN+LR
Sbjct: 43  VKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLR 101

Query: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIE----ALQEKEVEL----------SKAEKNA 110
              + LPE  +E+G L  EA +Y VQ LIE    ALQ+K   L          S  E+  
Sbjct: 102 DGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQ 161

Query: 111 MLNITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLF 164
           +L  T    V+ +H     +   YS +S+S +    NI     L L+  G  LF
Sbjct: 162 LLASTSKPVVKLLH---NRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLF 212


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 41/92 (44%), Positives = 60/92 (65%)

Query: 5  ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
          +TLNVGGK++TT  +T+  FP S L  M  G+    +   G  F+DRDG +F +IL+FLR
Sbjct: 7  VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66

Query: 65 TSHLDLPEDFQEMGLLRREADFYQVQPLIEAL 96
          T  L LP +F +   L+REA FY+++ L++ L
Sbjct: 67 THQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 41/92 (44%), Positives = 60/92 (65%)

Query: 5  ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
          +TLNVGGK++TT  +T+  FP S L  M  G+    +   G  F+DRDG +F +IL+FLR
Sbjct: 7  VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66

Query: 65 TSHLDLPEDFQEMGLLRREADFYQVQPLIEAL 96
          T  L LP +F +   L+REA FY+++ L++ L
Sbjct: 67 THQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 65/172 (37%), Positives = 89/172 (51%), Gaps = 15/172 (8%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
           + LNVGG LY T++ TLT   D+ML AMFSG+M    DS+G   IDR GK F  ILN+LR
Sbjct: 34  VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLR 92

Query: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIE----ALQEKEV--------ELSKAEKNAML 112
              + LPE  +E+  L  EA +Y VQ L+E    ALQ K+          ++ +++   L
Sbjct: 93  DGAVPLPESRREIEELLAEAKYYLVQGLVEECQAALQNKDTYEPFCKVPVITSSKEEQKL 152

Query: 113 NITLNQRVQTVHFTVREAPQIYSLSSSSMEVFNANIFSTSCLFLKLLGSKLF 164
             T N+    V      +   YS +S+S +    NI     L L+  G  LF
Sbjct: 153 IATSNK--PAVKLLYNRSNNKYSYTSNSDDNMLKNIELFDKLSLRFNGRVLF 202


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 52/124 (41%), Positives = 70/124 (56%), Gaps = 6/124 (4%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
           I LNVGGK ++TS  TLT  PDS   ++ SG++ T +D  G  FIDRD  VF  ILNFLR
Sbjct: 21  IHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLR 80

Query: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNITLNQRVQTVH 124
           T  LD P       LL  EA FY + PL+  LQ +E    + ++++  N+  N  +    
Sbjct: 81  TKELD-PRGVHGSSLL-HEAQFYGLTPLVRRLQLRE----ELDRSSCGNVLFNGYLPPPV 134

Query: 125 FTVR 128
           F V+
Sbjct: 135 FPVK 138


>gi|45387953 potassium channel tetramerization domain containing
          18 [Homo sapiens]
          Length = 426

 Score = 82.0 bits (201), Expect = 5e-16
 Identities = 39/87 (44%), Positives = 56/87 (64%), Gaps = 1/87 (1%)

Query: 3  DPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNF 62
          D + LNVGG +YT    +L  F DSML +MFSG+ P K D  G C IDRDG++F+Y+L++
Sbjct: 12 DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71

Query: 63 LRTSHLDLPEDFQEMGLLRREADFYQV 89
          L    + +P D Q    L+ EAD++ +
Sbjct: 72 LH-GEVQIPTDEQTRIALQEEADYFGI 97


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 44/110 (40%), Positives = 66/110 (60%), Gaps = 3/110 (2%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
           + LN+GG  +TT L+TL  + D+ML AMFSG+     DS+G  FIDRDG  F  +LNFLR
Sbjct: 53  VPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNFLR 112

Query: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAEKNAMLNI 114
           +   DLP   + +  + +EA +Y + PL+E L+  +    +  + A L +
Sbjct: 113 SG--DLPPR-ERVRAVYKEAQYYAIGPLLEQLENMQPLKGEKVRQAFLGL 159


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 79.7 bits (195), Expect = 2e-15
 Identities = 43/92 (46%), Positives = 55/92 (59%), Gaps = 2/92 (2%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
           + LNVGG  ++TS  TL   PDS   ++ SG++ T RD  G  FIDRD   F  ILNFLR
Sbjct: 20  VQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPILNFLR 79

Query: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLIEAL 96
           T  LDL      + +LR EA+FY + PL+  L
Sbjct: 80  TKELDLRG--VSINVLRHEAEFYGITPLVRRL 109


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 78.6 bits (192), Expect = 5e-15
 Identities = 41/98 (41%), Positives = 59/98 (60%), Gaps = 4/98 (4%)

Query: 1   MSDPITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYIL 60
           MS  + LNVGG+ +TT+L TL  FP S L  MFS       D++G  FIDR    FR IL
Sbjct: 31  MSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPIL 90

Query: 61  NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQE 98
           ++LRT  +      Q +  + REA FY+++PL++ L++
Sbjct: 91  DYLRTGQVPT----QHIPEVYREAQFYEIKPLVKLLED 124


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 59/172 (34%), Positives = 90/172 (52%), Gaps = 14/172 (8%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64
           + LNVGG LY T++  LT   D+ML AMFSG+M    D +G   IDR GK F  ILN+LR
Sbjct: 30  VQLNVGGSLYYTTVRALTRH-DTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLR 88

Query: 65  TSHLDLPEDFQEMGLLRREADFYQVQPLI----EALQEKEVELSKAEKNAMLNITLNQRV 120
              + LP++ QE+  L  EA +Y +Q L+     ALQ+K+ +  +   N  +  +L +  
Sbjct: 89  DDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKK-DSYQPVCNIPIITSLKEEE 147

Query: 121 QTVHFTVREAPQI--------YSLSSSSMEVFNANIFSTSCLFLKLLGSKLF 164
           + +  + +   ++        YS +S+S +    NI     L L+  G  LF
Sbjct: 148 RLIESSTKPVVKLLYNRSNNKYSYTSNSDDHLLKNIELFDKLSLRFNGRVLF 199


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 63.9 bits (154), Expect = 1e-10
 Identities = 41/99 (41%), Positives = 59/99 (59%), Gaps = 4/99 (4%)

Query: 2   SDPITLNVGGKLYTTSLATLTSF-PDSMLGAMFSGK--MPTKRDSQGNCFIDRDGKVFRY 58
           +D +TLNVGG+ +TT+ +TL +  PDSML  MF  K     K+D +G   IDR  + F  
Sbjct: 88  TDWLTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHRGAFLIDRSPEYFEP 147

Query: 59  ILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ 97
           ILN+LR   L + +    +G+L  EA F+ +  LIE L+
Sbjct: 148 ILNYLRHGQLIVNDGINLLGVL-EEARFFGIDSLIEHLE 185


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 39/99 (39%), Positives = 55/99 (55%), Gaps = 2/99 (2%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGK-MPTKRDSQGNCFIDRDGKVFRYILNFL 63
           + LNVGG ++ T+  TL     S L  +  G+ + + RD  G   IDRD   F  ILNFL
Sbjct: 33  VRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSDRDETGAYLIDRDPTYFGPILNFL 92

Query: 64  RTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVE 102
           R   L L +D  E G+L  EA+FY + PLI  ++++  E
Sbjct: 93  RHGKLVLDKDMAEEGVL-EEAEFYNIGPLIRIIKDRMEE 130


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%)

Query: 2   SDPITLNVGGKLYTTSLATLTSF-PDSMLGAMFSGK--MPTKRDSQGNCFIDRDGKVFRY 58
           +D +TL+VGG+ +TT+ +TL +  PD ML  MF  K     K+D +G   ID+  + F  
Sbjct: 88  TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEP 147

Query: 59  ILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ 97
           ILN+LR   L + +    +G+L  EA F+ +  LIE L+
Sbjct: 148 ILNYLRHGQLIVNDGIDLLGVL-EEARFFGIDSLIEHLK 185


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%)

Query: 2   SDPITLNVGGKLYTTSLATLTSF-PDSMLGAMFSGK--MPTKRDSQGNCFIDRDGKVFRY 58
           +D +TL+VGG+ +TT+ +TL +  PD ML  MF  K     K+D +G   ID+  + F  
Sbjct: 88  TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEP 147

Query: 59  ILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ 97
           ILN+LR   L + +    +G+L  EA F+ +  LIE L+
Sbjct: 148 ILNYLRHGQLIVNDGIDLLGVL-EEARFFGIDSLIEHLK 185


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 38/99 (38%), Positives = 58/99 (58%), Gaps = 4/99 (4%)

Query: 2   SDPITLNVGGKLYTTSLATLTSF-PDSMLGAMFSGK--MPTKRDSQGNCFIDRDGKVFRY 58
           +D +TL+VGG+ +TT+ +TL +  PD ML  MF  K     K+D +G   ID+  + F  
Sbjct: 88  TDWLTLHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNKQDHRGAFLIDQSPEYFEP 147

Query: 59  ILNFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQ 97
           ILN+LR   L + +    +G+L  EA F+ +  LIE L+
Sbjct: 148 ILNYLRHGQLIVNDGIDLLGVL-EEARFFGIDSLIEHLK 185


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 34/97 (35%), Positives = 52/97 (53%), Gaps = 3/97 (3%)

Query: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGK--MPTKRDSQGNCFIDRDGKVFRYILNF 62
           + LNVGG  + T+  TL   P S L  +      + + +D  G   IDRD   F  +LN+
Sbjct: 46  VRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSDKDETGAYLIDRDPTYFGPVLNY 105

Query: 63  LRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEK 99
           LR   L + +D  E G+L  EA+FY +  LI+ +++K
Sbjct: 106 LRHGKLVINKDLAEEGVL-EEAEFYNITSLIKLVKDK 141


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,195,934
Number of Sequences: 37866
Number of extensions: 380607
Number of successful extensions: 1120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1003
Number of HSP's gapped (non-prelim): 90
length of query: 260
length of database: 18,247,518
effective HSP length: 100
effective length of query: 160
effective length of database: 14,460,918
effective search space: 2313746880
effective search space used: 2313746880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.