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Search of human proteins with 70980549
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70980549 programmed cell death 11 [Homo sapiens]
(1871 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70980549 programmed cell death 11 [Homo sapiens] 3679 0.0
gi|124256489 crooked neck-like 1 protein [Homo sapiens] 65 8e-10
gi|148746195 trichohyalin [Homo sapiens] 60 3e-08
gi|55770906 XPA binding protein 2 [Homo sapiens] 59 6e-08
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 58 8e-08
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 58 1e-07
gi|104526627 triadin [Homo sapiens] 57 1e-07
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 55 6e-07
gi|11067749 bromodomain containing protein 3 [Homo sapiens] 55 6e-07
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 55 8e-07
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 54 1e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 53 3e-06
gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa p... 53 3e-06
gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapi... 53 3e-06
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 53 3e-06
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 53 3e-06
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 52 5e-06
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 52 5e-06
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 52 5e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 52 7e-06
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 52 7e-06
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 52 7e-06
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 52 7e-06
gi|4557495 cleavage stimulation factor subunit 3 isoform 1 [Homo... 52 7e-06
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 50 2e-05
gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens] 50 2e-05
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ... 50 3e-05
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 50 3e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 4e-05
>gi|70980549 programmed cell death 11 [Homo sapiens]
Length = 1871
Score = 3679 bits (9541), Expect = 0.0
Identities = 1871/1871 (100%), Positives = 1871/1871 (100%)
Query: 1 MANLEESFPRGGTRKIHKPEKAFQQSVEQDNLFDISTEEGSTKRKKSQKGPAKTKKLKIE 60
MANLEESFPRGGTRKIHKPEKAFQQSVEQDNLFDISTEEGSTKRKKSQKGPAKTKKLKIE
Sbjct: 1 MANLEESFPRGGTRKIHKPEKAFQQSVEQDNLFDISTEEGSTKRKKSQKGPAKTKKLKIE 60
Query: 61 KRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGFVQVTEICDAYT 120
KRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGFVQVTEICDAYT
Sbjct: 61 KRESSKSAREKFEILSVESLCEGMRILGCVKEVNELELVISLPNGLQGFVQVTEICDAYT 120
Query: 121 KKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLS 180
KKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLS
Sbjct: 121 KKLNEQVTQEQPLKDLLHLPELFSPGMLVRCVVSSLGITDRGKKSVKLSLNPKNVNRVLS 180
Query: 181 AEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLN 240
AEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLN
Sbjct: 181 AEALKPGMLLTGTVSSLEDHGYLVDIGVDGTRAFLPLLKAQEYIRQKNKGAKLKVGQYLN 240
Query: 241 CIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNF 300
CIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNF
Sbjct: 241 CIVEKVKGNGGVVSLSVGHSEVSTAIATEQQSWNLNNLLPGLVVKAQVQKVTPFGLTLNF 300
Query: 301 LTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLS 360
LTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLS
Sbjct: 301 LTFFTGVVDFMHLDPKKAGTYFSNQAVRACILCVHPRTRVVHLSLRPIFLQPGRPLTRLS 360
Query: 361 CQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNVFNPEAFKPGNTHKCR 420
CQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNVFNPEAFKPGNTHKCR
Sbjct: 361 CQNLGAVLDDVPVQGFFKKAGATFRLKDGVLAYARLSHLSDSKNVFNPEAFKPGNTHKCR 420
Query: 421 IIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLV 480
IIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLV
Sbjct: 421 IIDYSQMDELALLSLRTSIIEAQYLRYHDIEPGAVVKGTVLTIKSYGMLVKVGEQMRGLV 480
Query: 481 PPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAK 540
PPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAK
Sbjct: 481 PPMHLADILMKNPEKKYHIGDEVKCRVLLCDPEAKKLMMTLKKTLIESKLPVITCYADAK 540
Query: 541 PGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPERVFYTGQVVKVVVLNCE 600
PGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPERVFYTGQVVKVVVLNCE
Sbjct: 541 PGLQTHGFIIRVKDYGCIVKFYNNVQGLVPKHELSTEYIPDPERVFYTGQVVKVVVLNCE 600
Query: 601 PSKERMLLSFKLSSDPEPKKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNI 660
PSKERMLLSFKLSSDPEPKKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNI
Sbjct: 601 PSKERMLLSFKLSSDPEPKKEPAGHSQKKGKAINIGQLVDVKVLEKTKDGLEVAVLPHNI 660
Query: 661 RAFLPTSHLSDHVANGPLLHHWLQAGDILHRVLCLSQSEGRVLLCRKPALVSTVEGGQDP 720
RAFLPTSHLSDHVANGPLLHHWLQAGDILHRVLCLSQSEGRVLLCRKPALVSTVEGGQDP
Sbjct: 661 RAFLPTSHLSDHVANGPLLHHWLQAGDILHRVLCLSQSEGRVLLCRKPALVSTVEGGQDP 720
Query: 721 KNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTSTSDHFVEGQTVA 780
KNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTSTSDHFVEGQTVA
Sbjct: 721 KNFSEIHPGMLLIGFVKSIKDYGVFIQFPSGLSGLAPKAIMSDKFVTSTSDHFVEGQTVA 780
Query: 781 AKVTNVDEEKQRMLLSLRLSDCGLGDLAITSLLLLNQCLEELQGVRSLMSNRDSVLIQTL 840
AKVTNVDEEKQRMLLSLRLSDCGLGDLAITSLLLLNQCLEELQGVRSLMSNRDSVLIQTL
Sbjct: 781 AKVTNVDEEKQRMLLSLRLSDCGLGDLAITSLLLLNQCLEELQGVRSLMSNRDSVLIQTL 840
Query: 841 AEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDLVLKASRYHRAGQEVESGQKKKVVILNVD 900
AEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDLVLKASRYHRAGQEVESGQKKKVVILNVD
Sbjct: 841 AEMTPGMFLDLVVQEVLEDGSVVFSGGPVPDLVLKASRYHRAGQEVESGQKKKVVILNVD 900
Query: 901 LLKLEVHVSLHQDLVNRKARKLRKGSEHQAIVQHLEKSFAIASLVETGHLAAFSLTSHLN 960
LLKLEVHVSLHQDLVNRKARKLRKGSEHQAIVQHLEKSFAIASLVETGHLAAFSLTSHLN
Sbjct: 901 LLKLEVHVSLHQDLVNRKARKLRKGSEHQAIVQHLEKSFAIASLVETGHLAAFSLTSHLN 960
Query: 961 DTFRFDSEKLQVGQGVSLTLKTTEPGVTGLLLAVEGPAAKRTMRPTQKDSETVDEDEEVD 1020
DTFRFDSEKLQVGQGVSLTLKTTEPGVTGLLLAVEGPAAKRTMRPTQKDSETVDEDEEVD
Sbjct: 961 DTFRFDSEKLQVGQGVSLTLKTTEPGVTGLLLAVEGPAAKRTMRPTQKDSETVDEDEEVD 1020
Query: 1021 PALTVGTIKKHTLSIGDMVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTT 1080
PALTVGTIKKHTLSIGDMVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTT
Sbjct: 1021 PALTVGTIKKHTLSIGDMVTGTVKSIKPTHVVVTLEDGIIGCIHASHILDDVPEGTSPTT 1080
Query: 1081 KLKVGKTVTARVIGGRDMKTFKYLPISHPRFVRTIPELSVRPSELEDGHTALNTHSVSPM 1140
KLKVGKTVTARVIGGRDMKTFKYLPISHPRFVRTIPELSVRPSELEDGHTALNTHSVSPM
Sbjct: 1081 KLKVGKTVTARVIGGRDMKTFKYLPISHPRFVRTIPELSVRPSELEDGHTALNTHSVSPM 1140
Query: 1141 EKIKQYQAGQTVTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFRVG 1200
EKIKQYQAGQTVTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFRVG
Sbjct: 1141 EKIKQYQAGQTVTCFLKKYNVVKKWLEVEIAPDIRGRIPLLLTSLSFKVLKHPDKKFRVG 1200
Query: 1201 QALRATVVGPDSSKTLLCLSLTGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSI 1260
QALRATVVGPDSSKTLLCLSLTGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSI
Sbjct: 1201 QALRATVVGPDSSKTLLCLSLTGPHKLEEGEVAMGRVVKVTPNEGLTVSFPFGKIGTVSI 1260
Query: 1261 FHMSDSYSETPLEDFVPQKVVRCYILSTADNVLTLSLRSSRTNPETKSKVEDPEINSIQD 1320
FHMSDSYSETPLEDFVPQKVVRCYILSTADNVLTLSLRSSRTNPETKSKVEDPEINSIQD
Sbjct: 1261 FHMSDSYSETPLEDFVPQKVVRCYILSTADNVLTLSLRSSRTNPETKSKVEDPEINSIQD 1320
Query: 1321 IKEGQLLRGYVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTAR 1380
IKEGQLLRGYVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTAR
Sbjct: 1321 IKEGQLLRGYVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTAR 1380
Query: 1381 VLRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNE 1440
VLRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNE
Sbjct: 1381 VLRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNE 1440
Query: 1441 KKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLV 1500
KKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLV
Sbjct: 1441 KKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLV 1500
Query: 1501 DVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSE 1560
DVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSE
Sbjct: 1501 DVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSE 1560
Query: 1561 EDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSI 1620
EDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSI
Sbjct: 1561 EDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSI 1620
Query: 1621 LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV 1680
LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV
Sbjct: 1621 LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV 1680
Query: 1681 FERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQ 1740
FERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQ
Sbjct: 1681 FERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQ 1740
Query: 1741 AAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSV 1800
AAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSV
Sbjct: 1741 AAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSV 1800
Query: 1801 YIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALE 1860
YIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALE
Sbjct: 1801 YIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALE 1860
Query: 1861 YVEAKSSVLED 1871
YVEAKSSVLED
Sbjct: 1861 YVEAKSSVLED 1871
>gi|124256489 crooked neck-like 1 protein [Homo sapiens]
Length = 848
Score = 64.7 bits (156), Expect = 8e-10
Identities = 67/366 (18%), Positives = 147/366 (40%), Gaps = 47/366 (12%)
Query: 1517 LPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKE 1576
+PK + K +Q+++ + LPP + ++E+E K+ E
Sbjct: 173 IPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELNDYKLRKRKTFE 232
Query: 1577 RELEKQKAEK----ELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQA 1632
+ K + + ++ EE+L + R + ++R + + LWL+Y ++
Sbjct: 233 DNIRKNRTVISNWIKYAQWEESLKEIQR---ARSIYERALDVDYRNITLWLKYAEMEMKN 289
Query: 1633 TEIEKARAVAERALKTI----------SFREE------------------QEKLNVWVAL 1664
++ AR + +RA+ T+ ++ EE Q + W +
Sbjct: 290 RQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSY 349
Query: 1665 LNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQE 1724
+N E Y + ++ER V + +K ++ A K F A ++Y R ++ F E
Sbjct: 350 INFELRYKEVDRARTIYERFVLVHPDVKNWIKYARFEEKHAYFAHARKVYERAVEFFGDE 409
Query: 1725 ---KAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAK 1781
+ +++ + F + + + + AL+ + ++ ++ + E + GD +
Sbjct: 410 HMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQDAQELFKNYTIFEKKFGDRRGIE 469
Query: 1782 AI--------FENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKF 1833
I +E + P D W Y+ + + VR+++ER I ++ P + K
Sbjct: 470 DIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAI-ANVPPIQEKR 528
Query: 1834 FFKRYL 1839
+KRY+
Sbjct: 529 HWKRYI 534
Score = 60.8 bits (146), Expect = 1e-08
Identities = 72/353 (20%), Positives = 143/353 (40%), Gaps = 53/353 (15%)
Query: 1553 LAESSDSEEDEKPHQATIK-KSKKERELEKQKAEKELSRIEEALMDPGRQPESADD---- 1607
+A S+ + + P A +K K+ E ++ ++ +E E L+ P Q + D+
Sbjct: 162 MAASTAAGKQRIPKVAKVKNKAPAEVQITAEQLLREAKERELELLPPPPQQKITDEEELN 221
Query: 1608 ---------FDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKT---------- 1648
F+ + + W++Y + EI++AR++ ERAL
Sbjct: 222 DYKLRKRKTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLK 281
Query: 1649 -----ISFREEQEKLNVWVALLN--------------LENMYGSQESLTKVFERAVQYNE 1689
+ R+ N+W + +E M G+ +VFER +++
Sbjct: 282 YAEMEMKNRQVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQP 341
Query: 1690 PLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQ 1749
+ + + + ++ A +Y R + K WIKY F + + A + +V +
Sbjct: 342 EEQAWHSYINFELRYKEVDRARTIYERFVLVHPDVKN-WIKYARFEEKHAYFAHARKVYE 400
Query: 1750 RALECLPSKEHVD--VIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTI- 1806
RA+E EH+D + FA+ E + ER + I++ L K+ D ++ + TI
Sbjct: 401 RAVEFF-GDEHMDEHLYVAFAKFEENQKEFERVRVIYKYALDRISKQ-DAQELFKNYTIF 458
Query: 1807 --KHGSQKDVRDIF--ERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVK 1855
K G ++ + DI +R K + + DY + ++ + +AV+
Sbjct: 459 EKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRLVESDAEAEAVR 511
Score = 54.3 bits (129), Expect = 1e-06
Identities = 42/184 (22%), Positives = 80/184 (43%), Gaps = 8/184 (4%)
Query: 1679 KVFERAVQYNEP-LKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLR 1737
K FE ++ N + ++ A ++ Q A +Y R L + +W+KY ++
Sbjct: 229 KTFEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMK 288
Query: 1738 RSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDV 1797
Q + + RA+ LP K+ +E LG+ A+ +FE + P+
Sbjct: 289 NRQVNHARNIWDRAITTLPRVN--QFWYKYTYMEEMLGNVAGARQVFERWMEWQPEE-QA 345
Query: 1798 WSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAK 1857
W YI+ +++ R I+ER + L +K + K Y +E++H + V +
Sbjct: 346 WHSYINFELRYKEVDRARTIYERFV---LVHPDVKNWIK-YARFEEKHAYFAHARKVYER 401
Query: 1858 ALEY 1861
A+E+
Sbjct: 402 AVEF 405
Score = 52.4 bits (124), Expect = 4e-06
Identities = 58/231 (25%), Positives = 99/231 (42%), Gaps = 23/231 (9%)
Query: 1608 FDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNL 1667
++ V ++P++ W Y+ E E R V ERA+ + +E+ W + L
Sbjct: 480 YEEEVKANPHNYDAWFDYLRLVESDAEAEAVREVYERAIANVPPIQEKRH---WKRYIYL 536
Query: 1668 ENMYGSQESL-TKVFERAVQ-YNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQ-- 1723
Y E L K ER Q Y L++ H +AK E+ + L R+
Sbjct: 537 WINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRAL 596
Query: 1724 --------EKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLG 1775
+ ++ Y L+ + ++ ++ LE P E+ KFA+LE LG
Sbjct: 597 GTSIGKCPKNKLFKVYIELELQLREFDRCRKLYEKFLEFGP--ENCTSWIKFAELETILG 654
Query: 1776 DAERAKAIFENTLSTYPKRTD----VWSVYIDMTIKHGSQKDVRDIFERVI 1822
D +RA+AI+E +S R D +W YID I+ + R+++ R++
Sbjct: 655 DIDRARAIYELAIS--QPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLL 703
Score = 35.8 bits (81), Expect = 0.40
Identities = 22/80 (27%), Positives = 37/80 (46%), Gaps = 12/80 (15%)
Query: 1611 LVLSSPN---SSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNL 1667
L +S P +LW Y+ F ++ E E+ R + R L + + + VW++
Sbjct: 665 LAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLL------QRTQHVKVWISFAQF 718
Query: 1668 ENMYGSQESLTK---VFERA 1684
E G + SLTK ++E A
Sbjct: 719 ELSSGKEGSLTKCRQIYEEA 738
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 59.7 bits (143), Expect = 3e-08
Identities = 69/326 (21%), Positives = 139/326 (42%), Gaps = 48/326 (14%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E QL ++EE + + EER+++ ++ +++ ++ Q QEE ++ +E+++ ++ + +++
Sbjct: 902 EQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR 961
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKE-EAEETNVLPKEKQTKPAEAP 1529
++ + E++ + ++P+K E + YRE +E + EE +L +E++ + +
Sbjct: 962 KDKKLQQKEEQLLGEEPEKRRRQEREKK-----YREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 1530 RLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELS 1589
Q + EE++ + K+ +ERE + + E+EL
Sbjct: 1017 ERQYRK------------------KDELQQEEEQLLREEREKRRLQERE-RQYREEEELQ 1057
Query: 1590 RIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTI 1649
+ EE L+ R+ + +R LQ L E EK R R +
Sbjct: 1058 QEEEQLLGEERETRRRQELERQYRKEEE-----LQQEEEQLLREEPEKRR----RQERER 1108
Query: 1650 SFREEQEKLNVWVALL----------NLENMYGSQESLTKVFERAVQYNEPLKVFLHLAD 1699
REE+E LL LE Y +E + + E+ ++ + L
Sbjct: 1109 QCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELER 1168
Query: 1700 IYAKSEKFQEAGELYNRMLKRFRQEK 1725
Y + E+ Q+ E L R QEK
Sbjct: 1169 QYREEEELQQEEE----QLLREEQEK 1190
Score = 52.0 bits (123), Expect = 5e-06
Identities = 41/189 (21%), Positives = 87/189 (46%), Gaps = 6/189 (3%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E L +EE + E +ER ++ ++ Q+ ++ K QEE E + + Q+ + ++
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPK----EKQTKPA 1526
RE E++R+ ++ ++ L E + D + +E ++ + E++ K
Sbjct: 546 REQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE 605
Query: 1527 EAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEK 1586
E RL+ + + P + SEE E+ Q +++ ++ER ++ K E+
Sbjct: 606 EVERLEQEERREQRLKREE--PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREE 663
Query: 1587 ELSRIEEAL 1595
E R+E+ L
Sbjct: 664 EEERLEQRL 672
Score = 49.7 bits (117), Expect = 3e-05
Identities = 43/194 (22%), Positives = 95/194 (48%), Gaps = 15/194 (7%)
Query: 1414 LTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGREC 1473
L ++EER+ + +R+Q+ + + + E+ + QEE ++++P++ + Q+ E
Sbjct: 579 LKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 1474 RESGSEQ----ERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAP 1529
+E +Q E+ ++ ++ EE++ L RE +EE E L +E+Q + E
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQE-LAEEEQEQARERI 697
Query: 1530 RLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELS 1589
+ ++ W L+S A++ S+ +P + ++ ++E+E ++++ E EL
Sbjct: 698 KSRIPK---WQWQLES-------EADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Query: 1590 RIEEALMDPGRQPE 1603
EE +Q E
Sbjct: 748 WQEEERAHRQQQEE 761
Score = 47.8 bits (112), Expect = 1e-04
Identities = 62/280 (22%), Positives = 124/280 (44%), Gaps = 60/280 (21%)
Query: 1417 QEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQ----QPQKPQAQKRGGRE 1472
+EE + + EE GE++ +R ++ ++ ++E E+ +E+Q +P+K + Q+R R+
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERE-RQ 1109
Query: 1473 CRESGS---EQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAP 1529
CRE E+E++ ++ ++ +E ++ YRE +E +E L +E+ P +
Sbjct: 1110 CREEEELQQEEEQLLREEREKRRRQE----LERQYREEEEVQQEEEQLLREE---PEKRR 1162
Query: 1530 RLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELS 1589
R +L + E+E+ Q + ++E+E +Q+ E++
Sbjct: 1163 RQELERQY----------------------REEEELQQEEEQLLREEQEKRRQERERQY- 1199
Query: 1590 RIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAE-----R 1644
R EE L R+ D+ R S + W E EK AV + +
Sbjct: 1200 REEEELQRQKRKQRYRDEDQR-------SDLKW---------QWEPEKENAVRDNKVYCK 1243
Query: 1645 ALKTISFRE-EQEKLNVWVALLNLENMYGSQESLTKVFER 1683
+ FR+ E +L + +L+++ G Q+ + ER
Sbjct: 1244 GRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQER 1283
Score = 45.8 bits (107), Expect = 4e-04
Identities = 39/198 (19%), Positives = 89/198 (44%), Gaps = 18/198 (9%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E QL K E ++ E ++++ +++ +R ++ +K +EE +E+++ Q+ + Q+
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ--- 331
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNV-----------LPK 1519
E RE +E+ ++ ++ +E++ RE +EE E + L +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 1520 EKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKEREL 1579
E+Q + + R + + + L + E E+ H+ ++ + +RE
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 1580 EKQ----KAEKELSRIEE 1593
E++ K E+E R E+
Sbjct: 452 EERRDWLKREEETERHEQ 469
Score = 45.1 bits (105), Expect = 7e-04
Identities = 78/351 (22%), Positives = 141/351 (40%), Gaps = 73/351 (20%)
Query: 1414 LTKQEERKTEAEERDQKG-------EKKNQKRNEKKNQKGQ-----EEVEMPSKEKQQP- 1460
L +Q ER+ AEER Q+ E+K Q+R +++ ++ + EE ++ +E+ Q
Sbjct: 790 LREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQL 849
Query: 1461 -------QKPQAQKRGGRECRES----GSEQERVSK------KP-------KKAGLSEED 1496
Q+ Q ++R + R+ E+ER + KP K+ L +E+
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909
Query: 1497 DSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAES 1556
+ + RE + E+ +E+Q + E L+ + L +
Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969
Query: 1557 SDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSP 1616
+ E+P K+ ++ERE +K + E+EL + EE L+ R+ +++R
Sbjct: 970 EEQLLGEEPE----KRRRQERE-KKYREEEELQQEEEQLLREEREKRRRQEWER------ 1018
Query: 1617 NSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQES 1676
Q + ++ + E+ L REE+EK L E Y +E
Sbjct: 1019 --------------QYRKKDELQQEEEQLL-----REEREKRR----LQERERQYREEEE 1055
Query: 1677 LTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGE--LYNRMLKRFRQEK 1725
L + E+ + + L Y K E+ Q+ E L KR RQE+
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Score = 44.7 bits (104), Expect = 9e-04
Identities = 41/197 (20%), Positives = 87/197 (44%), Gaps = 31/197 (15%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQ----------- 1459
E +L + EE+ + E +Q+ ++ + ++ Q+ QE E ++E+Q
Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEF 204
Query: 1460 PQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPK 1519
P + Q ++R E R G E+++ ++ ++ + +E+ E KE + VL K
Sbjct: 205 PDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE---------EEKEWRKRETVLRK 255
Query: 1520 EKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESS---DSEEDEKPHQATIKKSKKE 1576
E++ E P+ Q L L L + +E+E+ Q ++ +
Sbjct: 256 EEEKLQEEEPQRQRE--------LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLR 307
Query: 1577 RELEKQKAEKELSRIEE 1593
R+ E+++ E++ R E+
Sbjct: 308 RKQEEERREQQEERREQ 324
Score = 44.7 bits (104), Expect = 9e-04
Identities = 52/258 (20%), Positives = 109/258 (42%), Gaps = 17/258 (6%)
Query: 1402 KPDVLSASLEGQLTKQEERKTEAEERD-QKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQP 1460
+P + E QL +RK EE+ Q+GE++ +R E+ + +EE ++ +E+++
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708
Query: 1461 QKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKE 1520
+ Q+ +E E+E++ ++ ++ L ++ + + + E EE + +E
Sbjct: 1709 FLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE 1768
Query: 1521 KQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDE-KPHQATIKKSKKEREL 1579
+ K E +L+ +S + EE + +P Q K +E +L
Sbjct: 1769 RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQL 1828
Query: 1580 EKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKAR 1639
+ ++ E+ L + + RQ + + F S LW + E +K R
Sbjct: 1829 QLEEQEQRLRQ------ERDRQYRAEEQFATQEKSRREEQELWQE---------EEQKRR 1873
Query: 1640 AVAERALKTISFREEQEK 1657
ER L+ R +Q++
Sbjct: 1874 QERERKLREEHIRRQQKE 1891
Score = 43.9 bits (102), Expect = 0.001
Identities = 41/196 (20%), Positives = 84/196 (42%), Gaps = 16/196 (8%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGR- 1471
Q ++ E+K E E R+Q+ +++ ++R + ++ + E + KQQ ++ Q ++R R
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488
Query: 1472 ------------ECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYRE---GKEEAEETNV 1516
E RE +E+ ++ ++ EE++ L E +E+ E
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 1517 LPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKE 1576
L K ++ K E R + D L + E E+ + +K+ + E
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 1577 RELEKQKAEKELSRIE 1592
R ++++ E+ L R E
Sbjct: 609 RLEQEERREQRLKREE 624
Score = 42.4 bits (98), Expect = 0.004
Identities = 56/260 (21%), Positives = 114/260 (43%), Gaps = 37/260 (14%)
Query: 1413 QLTKQEERK--TEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQ-------PQKP 1463
Q ++E+R+ T + ++K E+ Q+ + + + Q E ++ ++E+QQ ++
Sbjct: 757 QQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEE 816
Query: 1464 QAQKRGGRECRESG----SEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPK 1519
+ Q+R R RE E+E++ ++ + L EE+D L + R +E +
Sbjct: 817 KEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRR----DQ 872
Query: 1520 EKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDS--EEDEKPHQATIKKSKKER 1577
+ + + E + + + +A PAL +E+E+ Q ++ ++ +
Sbjct: 873 KWRWQLEEERKRRRHTLYA--------KPALQEQLRKEQQLLQEEEEELQREEREKRRRQ 924
Query: 1578 ELEKQ-KAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIE 1636
E E+Q + E++L + EE L+ R+ + +R LQ L E E
Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK-----LQQKEEQLLGEEPE 979
Query: 1637 KARAVAERALKTISFREEQE 1656
K R R + +REE+E
Sbjct: 980 KRR----RQEREKKYREEEE 995
Score = 41.2 bits (95), Expect = 0.010
Identities = 41/192 (21%), Positives = 89/192 (46%), Gaps = 12/192 (6%)
Query: 1411 EGQLTKQEERKTEAE-ERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRG 1469
E QL ++++ + E + R+Q+ ++ Q R E++ ++ QEE E ++ +Q ++ Q KR
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE-ERHEQKHEQERREQRLKRE 450
Query: 1470 GRECRE---SGSEQERVSKKPKKAGLS-EEDDSLVDVYYREGKEEAEETNVLPKEKQTKP 1525
E R+ E ER ++ +K L ++++ + + + +EE E +++ +
Sbjct: 451 QEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRRE 510
Query: 1526 AEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAE 1585
E R Q L L +++ + + K ++E+ LE+++ E
Sbjct: 511 QEERREQRLKRQEEEERLQQ------RLRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Query: 1586 KELSRIEEALMD 1597
+ L R +E D
Sbjct: 565 QRLKREQEERRD 576
Score = 40.8 bits (94), Expect = 0.013
Identities = 43/215 (20%), Positives = 94/215 (43%), Gaps = 30/215 (13%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEK------KNQKRNEKKNQ-------KGQEEVEMPSKEK 1457
EG+ +++ + E +R ++ E+ + Q+R E++ + KG E E P +E+
Sbjct: 150 EGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ 209
Query: 1458 QQPQKPQAQKRGGRECRESG---------SEQERVSKKPKKAGLSEEDDSLVDVY---YR 1505
+ ++ +R GRE ++ E+E + ++ L +E++ L + R
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQR 269
Query: 1506 EGKEEAE-----ETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSE 1560
E +EE E E L +E+Q + + RL+ + + E
Sbjct: 270 ELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERRE 329
Query: 1561 EDEKPHQATIKKSKKERELEKQKAEKELSRIEEAL 1595
+ E+ + +++ ++ER ++ + E+E R E+ L
Sbjct: 330 QQEERREQQLRREQEERREQQLRREQEEERREQQL 364
Score = 40.4 bits (93), Expect = 0.016
Identities = 39/190 (20%), Positives = 80/190 (42%), Gaps = 23/190 (12%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQK-RNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGR 1471
QL +QE + EE + E++ Q+ R +++++K +EE ++ + ++Q + Q R R
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 1472 ECRESGSEQERVSKKP-KKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPR 1530
E + E+E +P ++ G ++ + + +E + E E+Q E R
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSR 1858
Query: 1531 LQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSR 1590
+ W EE++K Q +K ++E +QK E+ +
Sbjct: 1859 REEQE--LW-------------------QEEEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897
Query: 1591 IEEALMDPGR 1600
+ E G+
Sbjct: 1898 VGEIKSQEGK 1907
Score = 40.0 bits (92), Expect = 0.021
Identities = 37/197 (18%), Positives = 88/197 (44%), Gaps = 29/197 (14%)
Query: 1404 DVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQ---QP 1460
++L +G+ KQ++R+ + Q+ E+K ++ E +K +E+++ ++Q Q
Sbjct: 214 ELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 1461 QKPQAQKRGGRECR----ESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNV 1516
++ Q +K +E R E +Q+R+ ++ + EE+ RE +E E+
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEE 333
Query: 1517 LPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKE 1576
+++ + E R Q + +E+E+ Q ++ ++E
Sbjct: 334 RREQQLRREQEERREQ----------------------QLRREQEEERREQQLRREQEEE 371
Query: 1577 RELEKQKAEKELSRIEE 1593
R ++ + E++L R ++
Sbjct: 372 RREQQLRREQQLRREQQ 388
Score = 40.0 bits (92), Expect = 0.021
Identities = 54/250 (21%), Positives = 106/250 (42%), Gaps = 23/250 (9%)
Query: 1411 EGQLTKQE-ERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRG 1469
E QL +QE +RK EE + +++ Q+ +++K +EE ++ + ++Q + Q + R
Sbjct: 1633 EQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRK 1692
Query: 1470 GRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAP 1529
RE + QER ++ L EE R+ +EE E+ +++Q + E
Sbjct: 1693 FREEEQQLRRQER-----ERKFLQEEQQLRRQELERKFREE-EQLRQETEQEQLRRQERY 1746
Query: 1530 RLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELS 1589
R L + L P + + + +++ ++E++L Q+++++
Sbjct: 1747 RKILEE--------EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFR 1798
Query: 1590 RIEEALMDPGRQ---PESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERAL 1646
E+ + Q P+ D R L L+ L+ + RA + A
Sbjct: 1799 EEEQLRQEREEQQLRPQQRDGKYRW-----EEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 1647 KTISFREEQE 1656
+ S REEQE
Sbjct: 1854 QEKSRREEQE 1863
Score = 39.7 bits (91), Expect = 0.028
Identities = 43/192 (22%), Positives = 83/192 (43%), Gaps = 27/192 (14%)
Query: 1416 KQEERKTEAEERD-QKGEKKNQKRNEKKNQKGQE--EVEMPSKEKQQPQKPQAQKRGGRE 1472
+QEE + E RD Q E+ Q+R +K+ ++ +E E E S+++++ ++ Q+R
Sbjct: 114 RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEEL 173
Query: 1473 CRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQ 1532
R+ QER ++ ++ L + ET P E+Q + E L+
Sbjct: 174 WRQRQEWQEREERRAEEEQLQ--------------SCKGHETEEFPDEEQLRRRELLELR 219
Query: 1533 LSSGFAWNVGLDSLTPALPPLAESSDSEEDEK---PHQATIKKSKKERELEKQKAEKELS 1589
G + + EE+EK + ++K +++ + E+ + ++EL
Sbjct: 220 -------RKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 1590 RIEEALMDPGRQ 1601
EE L RQ
Sbjct: 273 EEEEQLRKLERQ 284
Score = 39.7 bits (91), Expect = 0.028
Identities = 41/199 (20%), Positives = 91/199 (45%), Gaps = 29/199 (14%)
Query: 1411 EGQLTKQEERKTEAEERDQKG---------EKKNQKRNEKKNQKGQEEVEMPSKEKQQPQ 1461
E QL ++E++ EA+ RD+K E++ ++R ++ ++K +EE ++ + ++QP
Sbjct: 1296 EEQLEREEQK--EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 1462 KPQAQKRGGRE----CRESG----SEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEE 1513
+ Q + R RE +E G E++R+ ++ ++ +E+ L +E
Sbjct: 1354 RRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL----------RCQE 1403
Query: 1514 TNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKS 1573
++ + + QLS + E EE+++ Q +K
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF 1463
Query: 1574 KKERELEKQKAEKELSRIE 1592
++E +L +++ E++L R E
Sbjct: 1464 REEEQLLQEREEQQLHRQE 1482
Score = 38.9 bits (89), Expect = 0.048
Identities = 40/200 (20%), Positives = 80/200 (40%), Gaps = 19/200 (9%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E QL ++E+ K E Q E++ +R ++K + E+ K + +P+K A +
Sbjct: 1180 EEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPR 1530
C+ +EQ R ED L D ++ ++ L E+Q + E R
Sbjct: 1240 VYCKGRENEQFR----------QLEDSQLRD------RQSQQDLQHLLGEQQERDREQER 1283
Query: 1531 LQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSR 1590
+ + L A+ D + E + + + ++E + +Q+ +++
Sbjct: 1284 RRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQE---EKQLLREEREEKRRRQETDRKFRE 1340
Query: 1591 IEEALMDPGRQPESADDFDR 1610
E+ L + QP + DR
Sbjct: 1341 EEQLLQEREEQPLRRQERDR 1360
Score = 38.5 bits (88), Expect = 0.062
Identities = 38/195 (19%), Positives = 87/195 (44%), Gaps = 21/195 (10%)
Query: 1410 LEGQLTKQEERKTEAEER-----------DQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQ 1458
L+ L +Q+ER E E R +++ E++ QK +++++K QEE ++ +E++
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE 1326
Query: 1459 QPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLP 1518
+ ++ Q R RE + E+E + ++ ++ L + +G++ EE L
Sbjct: 1327 EKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL--RHQEQGRKFLEEEQRLR 1384
Query: 1519 KEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERE 1578
++++ + QL L + EE+++ + + +E E
Sbjct: 1385 RQERERKFLKEEQQLR--------CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEE 1436
Query: 1579 LEKQKAEKELSRIEE 1593
+ ++ E+E +EE
Sbjct: 1437 QQVRRQERERKFLEE 1451
Score = 37.4 bits (85), Expect = 0.14
Identities = 37/185 (20%), Positives = 86/185 (46%), Gaps = 18/185 (9%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E + +QEE + EER+++ ++ +R ++ ++ Q+E E +E+ + ++ Q +R
Sbjct: 1112 EEEELQQEEEQLLREEREKR-RRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQY 1170
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPR 1530
RE E E+E++ ++ ++ E + YRE +E + K KQ E R
Sbjct: 1171 REEEELQQEEEQLLREEQEKRRQERERQ-----YREEEELQRQ-----KRKQRYRDEDQR 1220
Query: 1531 LQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKEREL-----EKQKAE 1585
L + W ++ + ++E+ + + ++ + +++L E+Q+ +
Sbjct: 1221 SDLK--WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERD 1278
Query: 1586 KELSR 1590
+E R
Sbjct: 1279 REQER 1283
Score = 37.4 bits (85), Expect = 0.14
Identities = 37/202 (18%), Positives = 89/202 (44%), Gaps = 28/202 (13%)
Query: 1411 EGQLTKQE-ERKTEAEERDQKGEKKNQKRNEKKNQK-GQEEVEMPSKEKQQPQKPQAQKR 1468
E +L +QE ERK EE+ + +++ Q+ + +++K +EE ++ +E+ + + + Q+
Sbjct: 1380 EQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQV 1439
Query: 1469 GGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEA 1528
+E E+E+ ++ + EE+ L + ++ + + L +E+Q + E
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQER 1499
Query: 1529 PRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKEL 1588
R E++ + + K ++E++L +Q+ +++
Sbjct: 1500 DR--------------------------KFREQELRSQEPERKFLEEEQQLHRQQRQRKF 1533
Query: 1589 SRIEEALMDPGRQPESADDFDR 1610
+ E+ L R + D DR
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDR 1555
Score = 36.6 bits (83), Expect = 0.24
Identities = 50/210 (23%), Positives = 96/210 (45%), Gaps = 31/210 (14%)
Query: 1412 GQLTK-QEERKTEAEERDQ----KGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQ 1466
GQ T EE++ + ++ + ++++Q+R E +++ Q E E + +Q+ Q+ Q
Sbjct: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDR--QLEEEPGQRRRQKRQE---Q 144
Query: 1467 KRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPA 1526
+R E E +QER+ ++ ++ D+ L +R+ +E +E++ + A
Sbjct: 145 ERELAEGEEQSEKQERLEQRDRQ----RRDEEL----WRQRQEW--------QEREERRA 188
Query: 1527 EAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSK---KERELEKQK 1583
E +LQ G D L E +EK Q ++ + +E E E +K
Sbjct: 189 EEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRK 248
Query: 1584 AEKELSRIEEALM--DPGRQPESADDFDRL 1611
E L + EE L +P RQ E ++ ++L
Sbjct: 249 RETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Score = 36.6 bits (83), Expect = 0.24
Identities = 51/220 (23%), Positives = 102/220 (46%), Gaps = 39/220 (17%)
Query: 1411 EGQLTKQEERKTEAEERDQKG-EKKNQKRNEKKNQKGQEEVEMPSKE------------- 1456
E L ++EE++ +ERD+K E++ Q R +++++K +E+ E+ S+E
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQ-ELRSQEPERKFLEEEQQLH 1525
Query: 1457 KQQPQKPQAQKRGGRECRESGSE--QERVSKKPKKAGLSEE-DDSLVDVYYREGKEEAEE 1513
+QQ Q+ Q+ +E G + Q+R K ++ L +E ++ + R+ K EE
Sbjct: 1526 RQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE 1585
Query: 1514 TNVLPKEKQTKPAE-APRLQLSSGFAWNVGLDSLTPALPPLAESSDSE--EDEKPHQATI 1570
V +E++ K E +L+ G L + D + EDE+ +
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEG-------------QQQLRQERDRKFREDEQ-----L 1627
Query: 1571 KKSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDR 1610
+ ++E++L +Q+ +++ E L R+ + D DR
Sbjct: 1628 LQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDR 1667
Score = 36.2 bits (82), Expect = 0.31
Identities = 34/177 (19%), Positives = 79/177 (44%), Gaps = 33/177 (18%)
Query: 1416 KQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRE 1475
++EE++ +ER++K ++ Q+ +++++K +EE ++ + ++Q Q + R E +
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 1476 SGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSS 1535
QER K ++ S+E + ++ EE L ++++ + QL
Sbjct: 1493 QLRRQERDRKFREQELRSQEPE----------RKFLEEEQQLHRQQRQRKFLQEEQQLRR 1542
Query: 1536 GFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIE 1592
E ++ Q +K ++E +L +++ E++LSR E
Sbjct: 1543 -----------------------QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
>gi|55770906 XPA binding protein 2 [Homo sapiens]
Length = 855
Score = 58.5 bits (140), Expect = 6e-08
Identities = 57/264 (21%), Positives = 103/264 (39%), Gaps = 57/264 (21%)
Query: 1621 LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV 1680
LW+ + F+ +++ AR + E+A K ++F++ + +VW LE + + + ++
Sbjct: 397 LWVAFAKFYEDNGQLDDARVILEKATK-VNFKQVDDLASVWCQCGELELRHENYDEALRL 455
Query: 1681 FERAVQY----------NEP--------LKVFLHLADIYAKSEKFQEAGELYNRMLKRFR 1722
+A +EP LKV+ LAD+ FQ +Y+R+L
Sbjct: 456 LRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLADLEESLGTFQSTKAVYDRILDLRI 515
Query: 1723 QEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKA 1782
+ I Y FL S + +R +
Sbjct: 516 ATPQIVINYAMFLEEHKYFEESFKAYERGI------------------------------ 545
Query: 1783 IFENTLSTYPKRTDVWSVYIDMTI-KHGSQK--DVRDIFERVIHLSLAPKRMKFFFKRYL 1839
+L +P +D+WS Y+ I ++G +K RD+FE+ + PK K + Y
Sbjct: 546 ----SLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALD-GCPPKYAKTLYLLYA 600
Query: 1840 DYEKQHGTEKDVQAVKAKALEYVE 1863
E++ G + AV +A VE
Sbjct: 601 QLEEEWGLARHAMAVYERATRAVE 624
Score = 52.4 bits (124), Expect = 4e-06
Identities = 45/207 (21%), Positives = 89/207 (42%), Gaps = 39/207 (18%)
Query: 1616 PNSSILWLQYMAFHLQ---ATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYG 1672
PN S +W Y+ + ++E+AR + E+AL + + +++ LE +G
Sbjct: 551 PNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAK---TLYLLYAQLEEEWG 607
Query: 1673 SQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYG 1732
V+ERA + EP + + + +IY K A E+Y
Sbjct: 608 LARHAMAVYERATRAVEPAQQY-DMFNIYIK-----RAAEIYG----------------- 644
Query: 1733 AFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYP 1792
+ + Q+A+E L + ++ +FA +E +LG+ +RA+AI+
Sbjct: 645 --------VTHTRGIYQKAIEVLSDEHAREMCLRFADMECKLGEIDRARAIYSFCSQICD 696
Query: 1793 KRTD--VWSVYIDMTIKHGSQKDVRDI 1817
RT W + D ++HG++ ++++
Sbjct: 697 PRTTGAFWQTWKDFEVRHGNEDTIKEM 723
Score = 46.2 bits (108), Expect = 3e-04
Identities = 48/240 (20%), Positives = 97/240 (40%), Gaps = 43/240 (17%)
Query: 1656 EKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPL-KVFLHLADIYAKSEKFQEAGELY 1714
+ L VW L +LE G+ +S V++R + ++ ++ A + + F+E+ + Y
Sbjct: 482 KSLKVWSMLADLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAY 541
Query: 1715 NRMLKRFRQEKA--VWIKYGAFLLRRSQAAASHR---VLQRALECLPSKEHVDVIAKFAQ 1769
R + F+ +W Y + R R + ++AL+ P K + +AQ
Sbjct: 542 ERGISLFKWPNVSDIWSTYLTKFIARYGGRKLERARDLFEQALDGCPPKYAKTLYLLYAQ 601
Query: 1770 LEFQLGDAERAKAIFEN-TLSTYP-KRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLS-- 1825
LE + G A A A++E T + P ++ D++++YI + R I+++ I +
Sbjct: 602 LEEEWGLARHAMAVYERATRAVEPAQQYDMFNIYIKRAAEIYGVTHTRGIYQKAIEVLSD 661
Query: 1826 ---------------------------------LAPKRMKFFFKRYLDYEKQHGTEKDVQ 1852
P+ F++ + D+E +HG E ++
Sbjct: 662 EHAREMCLRFADMECKLGEIDRARAIYSFCSQICDPRTTGAFWQTWKDFEVRHGNEDTIK 721
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 58.2 bits (139), Expect = 8e-08
Identities = 51/214 (23%), Positives = 91/214 (42%), Gaps = 20/214 (9%)
Query: 1392 ELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQE--- 1448
E + LP L L+ ++ K+E+++ E+D+ +K +K K+ +K +E
Sbjct: 511 EKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGR 570
Query: 1449 EVEMPSKE-----KQQPQK----------PQAQKRGGRECRESGSEQERVSKKPKKAGLS 1493
E + P KE + P K P+ + + G +E E+ + KK ++ G
Sbjct: 571 ETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEK--EKHKDKKKDREKGKK 628
Query: 1494 EEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPL 1553
++D + +G+E+ + P K P ++ L SL P LP
Sbjct: 629 DKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEK 688
Query: 1554 AESSDSEEDEKPHQATIKKSKKERELEKQKAEKE 1587
+ EK + K+ KK++E EK+K EKE
Sbjct: 689 LFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKE 722
Score = 37.7 bits (86), Expect = 0.11
Identities = 17/53 (32%), Positives = 33/53 (62%)
Query: 1410 LEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQK 1462
L +L +++E+ E E++ K EKK +K EK+ ++ + E E +EK++ +K
Sbjct: 685 LPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEK 737
Score = 34.7 bits (78), Expect = 0.90
Identities = 20/83 (24%), Positives = 44/83 (53%), Gaps = 2/83 (2%)
Query: 1388 KNLVELSFLPGDTGKPDVLSASLEGQLTKQ--EERKTEAEERDQKGEKKNQKRNEKKNQK 1445
K L F P + + SL L ++ EE++ E+ +K +K+ +K+ EK+ +K
Sbjct: 659 KELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEK 718
Query: 1446 GQEEVEMPSKEKQQPQKPQAQKR 1468
++E E +E+++ +K + + +
Sbjct: 719 KEKEREKEKREREKREKEKEKHK 741
Score = 34.3 bits (77), Expect = 1.2
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 9/78 (11%)
Query: 1408 ASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQK 1467
A L L E+ E +E+ ++ EKK K+ +KK ++ KEK++ +K + ++
Sbjct: 676 AMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKE---------KEKEKKEKEREKE 726
Query: 1468 RGGRECRESGSEQERVSK 1485
+ RE RE E+ + K
Sbjct: 727 KREREKREKEKEKHKHEK 744
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 57.8 bits (138), Expect = 1e-07
Identities = 45/239 (18%), Positives = 113/239 (47%), Gaps = 23/239 (9%)
Query: 1375 KLLTARV-LRLNHQKNLVELSFLPGDTGKP----DVLSASLEGQLTKQEERKTEAEERDQ 1429
K +++R ++LN + +V S + +P ++ E + K+ +++ E+E + +
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKE 62
Query: 1430 KGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKK 1489
+ E++ +KR +K +K + + E+++ ++ + ++R +E +E +++R K+ K+
Sbjct: 63 RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122
Query: 1490 AGLSEEDDSLVDVYYREGKEE--AEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLT 1547
G + ++ RE KEE EE ++K+ + E R + VG
Sbjct: 123 RGRTSKEGK-----ERERKEERKREERKERERKKEEREKERERKERKKRERKQVG----- 172
Query: 1548 PALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESAD 1606
+ + +E E+ + ++++KER+ E+++ E+ + E + ++ D
Sbjct: 173 ------EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKD 225
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/106 (29%), Positives = 61/106 (57%), Gaps = 4/106 (3%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E + +++ER+ + EER+++ E+K +K+ E+K Q G++E E KE+++ +K + ++
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERK-QVGEKEEERKEKERKERKKRERNRKER 196
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYRE---GKEEAEE 1513
++ RE +ER ++ KK +E +RE GK E +E
Sbjct: 197 KKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKE 242
Score = 36.2 bits (82), Expect = 0.31
Identities = 17/77 (22%), Positives = 45/77 (58%), Gaps = 2/77 (2%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRE 1472
Q+ ++EE + E E +++K K+ + R E+K ++ ++E KE+++ ++ + +++ R+
Sbjct: 170 QVGEKEEERKEKERKERK--KRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQ 227
Query: 1473 CRESGSEQERVSKKPKK 1489
E+ + +K +K
Sbjct: 228 TNWREKERGKRERKERK 244
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 57.4 bits (137), Expect = 1e-07
Identities = 58/244 (23%), Positives = 109/244 (44%), Gaps = 45/244 (18%)
Query: 1399 DTGKPDVLSASL-EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEK 1457
D G D + E L K+E K + E++++ K K K+ +KG+E+V +EK
Sbjct: 122 DDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKV----REK 177
Query: 1458 QQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKE-------- 1509
++P+K K + ++ E + ++K+ KKA +E+ + + GK+
Sbjct: 178 EKPEKKATHKE--KIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAA 235
Query: 1510 ---EAEETNVLPKEKQTK-PAEAPRLQLSSGFAWNVGLDSL----------TPALP---- 1551
E ++T PKEK+ K A + + +A+ + + +PA+P
Sbjct: 236 KVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLP 295
Query: 1552 -----------PLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGR 1600
P E + E+ + + T + KKE+E K+K+EKE + I+ +PG+
Sbjct: 296 TEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKE-TAIDVEKKEPGK 354
Query: 1601 QPES 1604
E+
Sbjct: 355 ASET 358
Score = 47.0 bits (110), Expect = 2e-04
Identities = 50/206 (24%), Positives = 91/206 (44%), Gaps = 29/206 (14%)
Query: 1414 LTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRG---- 1469
L ++E K +AE++ KK +K + KK + + +++ EK++P K K+G
Sbjct: 309 LEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDV---EKKEPGKASETKQGTVKI 365
Query: 1470 GRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAP 1529
+ E++ SKK KK E+ +E KE+ E PK++ + P++
Sbjct: 366 AAQAAAKKDEKKEDSKKTKKPAEVEQPKG----KKQEKKEKHVEPAKSPKKEHSVPSDKQ 421
Query: 1530 RLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSK--------KERELEK 1581
+ +G S+ A+P E E+ K + I+K K K++E K
Sbjct: 422 VKAKTERAKEEIGAVSIKKAVPGKKE----EKTTKTVEQEIRKEKSGKTSSILKDKEPIK 477
Query: 1582 QKAEKELSRIEEALMDPGRQPESADD 1607
K EK + ++E ++PE+ D
Sbjct: 478 GKEEKVPASLKE------KEPETKKD 497
Score = 43.5 bits (101), Expect = 0.002
Identities = 48/217 (22%), Positives = 96/217 (44%), Gaps = 25/217 (11%)
Query: 1399 DTGKPDVLSASLEGQLTKQEERKT----EAEERDQKGEKKNQKRNEKKNQKGQEEVEMPS 1454
+ K ++ + S++ + ++E KT E E R +K K + +K+ KG+EE S
Sbjct: 427 ERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPAS 486
Query: 1455 KEKQQPQ--KPQAQKRGGRECRE-----SGSEQERVS---KKPKKAGLSE------EDDS 1498
++++P+ K + + G+E + G ++E+ KK K +SE +D
Sbjct: 487 LKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIV 546
Query: 1499 LVDVYYREGKEE---AEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAE 1555
+ GK E ++ + EK KP + + ++ D P P
Sbjct: 547 KPEKTVSHGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPT--PKGT 604
Query: 1556 SSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIE 1592
S +E +K + + K+SK++ +++ + EK +R E
Sbjct: 605 SEVTESGKKKTEISEKESKEKADMKHLREEKVSTRKE 641
Score = 39.7 bits (91), Expect = 0.028
Identities = 47/187 (25%), Positives = 80/187 (42%), Gaps = 24/187 (12%)
Query: 1415 TKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECR 1474
TKQ K A Q KK++K+ + K K EVE P +KQ+ ++ + +
Sbjct: 358 TKQGTVKIAA----QAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKE 413
Query: 1475 ESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLS 1534
S ++V K ++A EE ++ GK+E EK TK E +
Sbjct: 414 HSVPSDKQVKAKTERA--KEEIGAVSIKKAVPGKKE---------EKTTKTVEQEIRKEK 462
Query: 1535 SGFAWNV--------GLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEK 1586
SG ++ G + PA E ++++DEK +A + K +L+ +K EK
Sbjct: 463 SGKTSSILKDKEPIKGKEEKVPASLKEKE-PETKKDEKMSKAGKEVKPKPPQLQGKKEEK 521
Query: 1587 ELSRIEE 1593
+I++
Sbjct: 522 PEPQIKK 528
Score = 34.3 bits (77), Expect = 1.2
Identities = 38/184 (20%), Positives = 78/184 (42%), Gaps = 31/184 (16%)
Query: 1408 ASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEK----KNQKGQEEVEMPSKEKQQPQKP 1463
A +E K++E+K + E + +K++ ++K K ++ +EE+ S +K P K
Sbjct: 387 AEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKK 446
Query: 1464 QAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQT 1523
+ + ++ ++ R K K + + ++ + + +GKEE ++ KE +T
Sbjct: 447 E------EKTTKTVEQEIRKEKSGKTSSILKDKEPI------KGKEEKVPASLKEKEPET 494
Query: 1524 KPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQK 1583
K E + + P +++EKP + IKK K EK +
Sbjct: 495 KKDEK--------------MSKAGKEVKPKPPQLQGKKEEKP-EPQIKKEAKPAISEKVQ 539
Query: 1584 AEKE 1587
K+
Sbjct: 540 IHKQ 543
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 55.1 bits (131), Expect = 6e-07
Identities = 49/204 (24%), Positives = 88/204 (43%), Gaps = 21/204 (10%)
Query: 1411 EGQLTKQEERKTEAEERDQK-----GEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQA 1465
EGQ+ +QEE+ E EE+ QK GE++ Q R +++ QEE +E+ Q Q+ Q
Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257
Query: 1466 QKRGG--RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQT 1523
+K+ RE E EQE K K+ EE + RE +E+ E +E++
Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317
Query: 1524 KPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQK 1583
+ E + + + E + ++K ++ E+E + QK
Sbjct: 318 QMREQE--------------EQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363
Query: 1584 AEKELSRIEEALMDPGRQPESADD 1607
E+++ + EE + Q ++
Sbjct: 364 QEEQVRKQEEQMRKQEEQMRKQEE 387
Score = 51.2 bits (121), Expect = 9e-06
Identities = 43/196 (21%), Positives = 96/196 (48%), Gaps = 17/196 (8%)
Query: 1411 EGQLTKQE--ERKTEAEERDQKGEKKNQKR--NEKKNQKGQEEVEMPSKEKQQ-PQKPQA 1465
EGQ+ +QE R+ E + R+Q+G+ + Q+ E++ Q G++E +M +E+Q Q+ Q
Sbjct: 156 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQM 215
Query: 1466 QKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKP 1525
QK+ + G ++E++ K+ ++ G EE V +E + + +E + +E+Q +
Sbjct: 216 QKQE----EQMGEQEEQMRKQEEQMGEQEE-----QVQKQEEQVQKQEEQMRKQEEQMRE 266
Query: 1526 AEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAE 1585
E Q+ + T E + +++ ++ +E+E + ++ E
Sbjct: 267 QEE---QMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323
Query: 1586 KELSRIEEALMDPGRQ 1601
+++ + EE + + Q
Sbjct: 324 EQMGKQEEQMWEQKEQ 339
Score = 49.7 bits (117), Expect = 3e-05
Identities = 50/248 (20%), Positives = 111/248 (44%), Gaps = 11/248 (4%)
Query: 1411 EGQLTKQE--ERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKR 1468
EGQ+ +QE R+ E + R+Q+G+ + Q+ + + Q+GQ + +Q+ Q + + +
Sbjct: 142 EGQVREQEGQVREQEGQVREQEGQVREQE-GQVREQEGQVREQEGQVREQEGQMGEQEGQ 200
Query: 1469 GGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEA 1528
G + + G ++E++ K+ ++ G EE + E +E+ ++ +E+ K E
Sbjct: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK----QEEQVQKQEEQ 256
Query: 1529 PRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKE-RELEKQKAEKE 1587
R Q + + E ++ EE + +++ +++ RE E+Q E+E
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
Query: 1588 LSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALK 1647
++ E G+Q E +++ +W Q Q +++K + +
Sbjct: 317 -EQMREQEEQMGKQEEQM--WEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEE 373
Query: 1648 TISFREEQ 1655
+ +EEQ
Sbjct: 374 QMRKQEEQ 381
Score = 44.7 bits (104), Expect = 9e-04
Identities = 44/214 (20%), Positives = 96/214 (44%), Gaps = 12/214 (5%)
Query: 1404 DVLSASLEGQLTKQE--ERKTEAEERDQKGEKKNQKR--NEKKNQKGQEEVEMPSKEKQ- 1458
D + EGQ+ +QE R+ E + R+Q+G+ + Q+ E++ Q ++E ++ +E Q
Sbjct: 44 DKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 103
Query: 1459 QPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLV-----DVYYREGKEEAEE 1513
+ Q+ Q +++ G+ + G +E+ + ++ G E + V V +EG+ +E
Sbjct: 104 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 163
Query: 1514 TNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKS 1573
V +E Q + E + G E E++E+ + +
Sbjct: 164 GQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMG 223
Query: 1574 KKERELEKQKAEKELSRIEEALMDPGRQPESADD 1607
++E ++ KQ E+++ EE + Q + ++
Sbjct: 224 EQEEQMRKQ--EEQMGEQEEQVQKQEEQVQKQEE 255
Score = 42.0 bits (97), Expect = 0.006
Identities = 27/97 (27%), Positives = 53/97 (54%), Gaps = 6/97 (6%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRE 1472
Q+ KQEE+ E EE+ QK E+ Q R +++ + QEE KQ+ Q + +++ G +
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEE--QVRKQEEQMRKQEE----QMRKQEEQMRKQEEQMGEQ 399
Query: 1473 CRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKE 1509
+ G ++E++ ++ ++ G +E + + E KE
Sbjct: 400 KEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 39.3 bits (90), Expect = 0.036
Identities = 35/124 (28%), Positives = 60/124 (48%), Gaps = 10/124 (8%)
Query: 1411 EGQLTKQEERKTEAEER-----DQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQA 1465
E Q+ +QEE+ E EE+ +Q E+K Q +K+ QEE +E+ Q Q+ Q
Sbjct: 309 EEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQV 368
Query: 1466 QKRGG--RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQT 1523
+K+ R+ E +QE +K ++ + E+ + + + +E E EE KE+
Sbjct: 369 RKQEEQMRKQEEQMRKQEEQMRKQEEQ-MGEQKEQMGE--QKEQMREQEEQMGEQKEQMR 425
Query: 1524 KPAE 1527
K E
Sbjct: 426 KQEE 429
Score = 38.1 bits (87), Expect = 0.081
Identities = 28/88 (31%), Positives = 48/88 (54%), Gaps = 5/88 (5%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQ--AQKR 1468
E Q+ +QEE+ + EE+ +K E+ Q R +++ + QEE +E+ QK Q QK
Sbjct: 351 EEQMGEQEEQMQKQEEQVRKQEE--QMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKE 408
Query: 1469 GGRECRES-GSEQERVSKKPKKAGLSEE 1495
RE E G ++E++ K+ + G +E
Sbjct: 409 QMREQEEQMGEQKEQMRKQEEHMGEQKE 436
>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
Length = 726
Score = 55.1 bits (131), Expect = 6e-07
Identities = 58/223 (26%), Positives = 104/223 (46%), Gaps = 22/223 (9%)
Query: 1416 KQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRE 1475
K+++ K E E++ + EK+ +K K ++ + +V P+K+ QQ + P +
Sbjct: 489 KKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAP---AKKANSTTT 545
Query: 1476 SGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTK-----PAEAPR 1530
+G + ++ K+ + SEE++ + + Y E ++ + + N LP EK + + P
Sbjct: 546 AGRQLKKGGKQASASYDSEEEEEGLPMSYDEKRQLSLDINRLPGEKLGRVVHIIQSREPS 605
Query: 1531 LQLSSGFAWNVGLDSLTPA----LPPLAESSDSEEDEKPHQATIK----KSKKERELEKQ 1582
L+ S+ + ++L P L +S ++ KP A+ K KSK+E EK+
Sbjct: 606 LRDSNPDEIEIDFETLKPTTLRELERYVKSCLQKKQRKPFSASGKKQAAKSKEELAQEKK 665
Query: 1583 K-AEKELSRIEEALMD---PGR--QPESADDFDRLVLSSPNSS 1619
K EK L + L P R +P SA LSS +SS
Sbjct: 666 KELEKRLQDVSGQLSSSKKPARKEKPGSAPSGGPSRLSSSSSS 708
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 54.7 bits (130), Expect = 8e-07
Identities = 73/331 (22%), Positives = 143/331 (43%), Gaps = 45/331 (13%)
Query: 1406 LSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEK-----KNQKGQEEVEMPSKEKQQP 1460
L+ E ++ +QEE+ E EE+ Q+ E+K +++ EK + + QEE+ +EK +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353
Query: 1461 QKPQAQKRGGRECRESGSEQERVSKKPKKAGLS-EEDDSLVDVYYREGKEEAEETNVLPK 1519
Q+ ++ + R+ E+ K ++ + E+++ + ++ + ++E +
Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413
Query: 1520 EKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKEREL 1579
+++ K E + Q W E E++EK + K ++E ++
Sbjct: 414 QEEEKIREQEKRQEQEAKMWR-------------QEEKIREQEEKIREQEKKMWRQEEKI 460
Query: 1580 -EKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKA 1638
E++K +E R E+ M RQ E + + +W Q H Q +I K
Sbjct: 461 HEQEKIREEEKRQEQEEM--WRQEEKIHEQEE----------IWRQKEKMHEQEEKIRKQ 508
Query: 1639 RAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLA 1698
R + I RE++EK+ E M+ +E K+ E+ + E K +H
Sbjct: 509 EEKVWRQEEKI--REQEEKIRE-----QEEKMWRQEE---KIREQEEMWREEEK--MHEQ 556
Query: 1699 DIYAKSEKFQEAGELYNRMLKRFR-QEKAVW 1728
+ + EK QE + R ++ R QE+ VW
Sbjct: 557 EKIWEEEKRQEQEDKMWRQEEKIREQEEKVW 587
Score = 50.1 bits (118), Expect = 2e-05
Identities = 43/189 (22%), Positives = 95/189 (50%), Gaps = 24/189 (12%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E EE+ + E+K +++ EK+ ++ ++ + K ++Q +K Q Q+
Sbjct: 569 EDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKI 628
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPR 1530
RE E EQE ++++ ++ + E+++ + + E +E EET +EK + + R
Sbjct: 629 REQEEKIREQEEMTQEQEEK-MGEQEEKMCE--QEEKMQEQEETMWRQEEKIREQEKKIR 685
Query: 1531 LQLSSGFAWNVGLDSLTPALPPLAESSD--SEEDEKPHQATIKKSKKERELEKQKAEKEL 1588
Q + E + E++EK + K ++E ++++Q E+++
Sbjct: 686 EQEEK-----------------IREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ--EEKM 726
Query: 1589 SRIEEALMD 1597
R EE + +
Sbjct: 727 RRQEEKMWE 735
Score = 35.0 bits (79), Expect = 0.69
Identities = 26/103 (25%), Positives = 53/103 (51%), Gaps = 6/103 (5%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E EE + E+K R ++K + QEE +E Q Q+ + ++
Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEK--IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEE 1513
+ C ++E++ ++ +K EE +V R+ +E+ +E
Sbjct: 711 KMC----EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 53.9 bits (128), Expect = 1e-06
Identities = 72/328 (21%), Positives = 140/328 (42%), Gaps = 43/328 (13%)
Query: 1406 LSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEK---KNQKGQEEVEMPSKEKQQPQK 1462
L+ E ++ +QEE+ E EE+ Q+ E+K +++ EK + +K + + EM EK++ +
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM-MWEKEEKMR 413
Query: 1463 PQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQ 1522
Q + +E + E+ K+ K L E+ + +E K + EE +++Q
Sbjct: 414 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 473
Query: 1523 TKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDS--EEDEKPHQATIKKSKKERELE 1580
+ A+ R + + + + E + ++EK H+ +K RE E
Sbjct: 474 EQEAKMWRQE-----------EKIREQEEKIREQEEKMWRQEEKIHE-----QEKIREEE 517
Query: 1581 KQKAEKELSRIEEALMDP---GRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEK 1637
K++ ++E+ R EE + + RQ E + + + +W Q H Q +I +
Sbjct: 518 KRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEK--MWRQEEKMHDQEEKIRE 575
Query: 1638 ARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHL 1697
R + I RE++EK+ E QE +T+ E + E
Sbjct: 576 QEEKVWRQEEKI--REQEEKIR------EQEEKIREQEEMTQEQEEKMGEQE-------- 619
Query: 1698 ADIYAKSEKFQEAGELYNRMLKRFRQEK 1725
+ + EK QE E R ++ R+++
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKIREQE 647
Score = 44.7 bits (104), Expect = 9e-04
Identities = 39/189 (20%), Positives = 91/189 (48%), Gaps = 28/189 (14%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRE 1472
++ +Q+E+ E EE+ +K E+K ++ EK + + ++ E K +Q +K + Q+ RE
Sbjct: 537 EIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIRE 596
Query: 1473 CRESGSEQERVSKKPKKAGLSEEDDSLVD----VYYREGKEEAEETNVLPKEKQTKPAEA 1528
E EQE ++++ ++ + E+++ + + + +E K +E + +EK+ + E
Sbjct: 597 QEEKIREQEEMTQEQEEK-MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEE 655
Query: 1529 PRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKEL 1588
+ E E++EK + K ++E ++++Q E+++
Sbjct: 656 KIRE---------------------QEEMMQEQEEKMWEQEEKMCEQEEKMQEQ--EEKM 692
Query: 1589 SRIEEALMD 1597
R EE + +
Sbjct: 693 RRQEEKMWE 701
Score = 43.5 bits (101), Expect = 0.002
Identities = 30/111 (27%), Positives = 61/111 (54%), Gaps = 3/111 (2%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E EE Q+ E+K ++ EK ++ ++ E K ++Q +K + Q++
Sbjct: 591 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKI 650
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEK 1521
RE E EQE + ++ ++ + E+++ + + E +E EE +EK
Sbjct: 651 REQEEKIREQEEMMQEQEEK-MWEQEEKMCE--QEEKMQEQEEKMRRQEEK 698
Score = 41.6 bits (96), Expect = 0.007
Identities = 27/117 (23%), Positives = 62/117 (52%), Gaps = 4/117 (3%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E EE+ ++ E+ Q++ EK ++ ++ E K ++Q +K + Q+
Sbjct: 584 EEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAE 1527
RE + EQE ++ ++ +E+ ++ +E K +E + +E++ + E
Sbjct: 644 REQEKKIREQEEKIREQEEMMQEQEE----KMWEQEEKMCEQEEKMQEQEEKMRRQE 696
Score = 40.4 bits (93), Expect = 0.016
Identities = 31/122 (25%), Positives = 62/122 (50%), Gaps = 3/122 (2%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E EE+ ++ E+K +++ E ++ ++ E K +Q +K Q Q+
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPR 1530
R E EQE+ ++ ++ + E+++ + + E E EE +EK + E R
Sbjct: 637 RRQEEKIREQEKKIREQEEK-IREQEEMMQE--QEEKMWEQEEKMCEQEEKMQEQEEKMR 693
Query: 1531 LQ 1532
Q
Sbjct: 694 RQ 695
Score = 37.4 bits (85), Expect = 0.14
Identities = 26/103 (25%), Positives = 55/103 (53%), Gaps = 6/103 (5%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E EE+ ++ E+K R ++K + QEE +E Q Q+ + ++
Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEK--IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 676
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEE 1513
+ C ++E++ ++ +K EE +V R+ +E+ +E
Sbjct: 677 KMC----EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
Score = 35.0 bits (79), Expect = 0.69
Identities = 23/89 (25%), Positives = 47/89 (52%), Gaps = 1/89 (1%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E E++ ++ E+K +++ E ++ ++ E K +Q +K Q Q+
Sbjct: 633 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSL 1499
R E EQE V + ++ + E + L
Sbjct: 693 RRQEEKMWEQE-VRLRQQEEKMQEHQEHL 720
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 52.8 bits (125), Expect = 3e-06
Identities = 32/120 (26%), Positives = 61/120 (50%), Gaps = 2/120 (1%)
Query: 1414 LTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGREC 1473
L+ +EE + E EE ++ E + ++ K+ ++G+E+ +E+++ +K + +K +E
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302
Query: 1474 RESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQL 1533
E E+E + + + LS+E++ E E E +L KEKQ K E R L
Sbjct: 2303 EEVFEEKEEIMSEEETESLSDEEEEEESCSLEE--EVDREKEILKKEKQFKLQEQRRKSL 2360
Score = 45.4 bits (106), Expect = 5e-04
Identities = 90/398 (22%), Positives = 173/398 (43%), Gaps = 40/398 (10%)
Query: 1404 DVLSASLEGQLTKQEERKTEAEERDQKGEKKNQK-RNEKKNQKGQEEVEMPSKEKQQPQK 1462
++LS+ + Q K EE T EE ++GE+K Q+ E+++ QEE + + ++
Sbjct: 1527 NMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHI--QEEHKWARIHR---KR 1581
Query: 1463 PQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQ 1522
+A+K+ +E R+ E+E+++++ ++ L++E+ L Y + +++ E K Q
Sbjct: 1582 ARAEKKRAQEERKLAQEEEKLAQEERQ--LAQEERKLAQAYVKITQDDREMAQAEGKFAQ 1639
Query: 1523 TKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSD--SEEDEKPHQATIKKSKKERELE 1580
+ A R + S A + L LA+ + + E+EK KK K E++
Sbjct: 1640 KEETLAQRGEKLSQEA-----EKLAQKRKKLAKKWEKVAREEEK----LAKKGGKLAEVK 1690
Query: 1581 KQKAEK--ELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKA 1638
A+K EL + E+ L ++ E A + + L S W + + +E+
Sbjct: 1691 NILAQKVEELPQREQNL--DWQEKELAQELEELEWDMEELS--WKEEELNQEEGKLVEEK 1746
Query: 1639 RAVAER----ALKTISFREEQEKLNVWVALL--NLENMYGSQESLTKVFERAVQYNEPLK 1692
+ +AE A + EE+ KL LL E + +E + + ER + E L
Sbjct: 1747 KKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQL- 1805
Query: 1693 VFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRAL 1752
I K + Q+ N M + + + ++ K +++ A ++ QR
Sbjct: 1806 -------IEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLAQEKEKLAQRKE 1858
Query: 1753 ECLPSKEHVDVIAK-FAQLEFQLGDAERAKAIFENTLS 1789
L +KE + K Q++ +LG + A E L+
Sbjct: 1859 NLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLT 1896
Score = 41.6 bits (96), Expect = 0.007
Identities = 38/199 (19%), Positives = 90/199 (45%), Gaps = 29/199 (14%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRE 1472
++ +EE+ TE E + K ++ + + + G EE E+ K++ +K + KRG +
Sbjct: 2152 RMINKEEKMTEEESK--LARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKP 2209
Query: 1473 CRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQ 1532
+ S+ + V + SEE +SL+D ++ +EE +E++ + E
Sbjct: 2210 KEKFSSQVDEVESEEH---FSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVRE-- 2264
Query: 1533 LSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIE 1592
E + +E+E+ + ++K ++E++ +K++ +KE + +
Sbjct: 2265 ----------------------EEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEK 2302
Query: 1593 EALMDPGRQPESADDFDRL 1611
E + + + S ++ + L
Sbjct: 2303 EEVFEEKEEIMSEEETESL 2321
Score = 41.2 bits (95), Expect = 0.010
Identities = 77/381 (20%), Positives = 146/381 (38%), Gaps = 54/381 (14%)
Query: 1417 QEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRG--GRECR 1474
QEERK EE E++ + E+K + ++ +E Q + AQK +
Sbjct: 1590 QEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGE 1649
Query: 1475 ESGSEQERVSKKPKKAG-----LSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAP 1529
+ E E++++K KK ++ E++ L ++G + AE N+L ++ + P
Sbjct: 1650 KLSQEAEKLAQKRKKLAKKWEKVAREEEKLA----KKGGKLAEVKNILAQKVEELP---- 1701
Query: 1530 RLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKA----- 1584
Q W E ++E E+ + S KE EL +++
Sbjct: 1702 --QREQNLDWQ--------------EKELAQELEELEWDMEELSWKEEELNQEEGKLVEE 1745
Query: 1585 EKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAER 1644
+K+L+ EEAL Q E + + + I + +A H + E+ R +R
Sbjct: 1746 KKKLAEEEEAL---AWQREKLSEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKR 1802
Query: 1645 ALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKS 1704
+ +K W+ S E LTK + + Y + + ++ +
Sbjct: 1803 EQLIEKKMKLAQKRERWI---------NSMEELTK--NKMILYQKK-NLAQEKKNLAQEK 1850
Query: 1705 EKFQEAGE--LYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHV- 1761
EK + E LYN+ +++ V +K + + A ++ Q + KE +
Sbjct: 1851 EKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKEKLA 1910
Query: 1762 DVIAKFAQLEFQLGDAERAKA 1782
+ K Q+E L + A
Sbjct: 1911 ETEKKLVQVEDSLAKKQEKLA 1931
Score = 40.4 bits (93), Expect = 0.016
Identities = 46/209 (22%), Positives = 99/209 (47%), Gaps = 33/209 (15%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKE----KQQPQKPQAQKR 1468
+LT+ E + T+ E K K + K+ + E+ ++ KE +++ + + +K+
Sbjct: 2082 KLTRDERKLTQEEI---KMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKK 2138
Query: 1469 GGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYR---EGKEEA--EETNVLP----- 1518
R+ R+ ++ R+ K +K ++EE+ L + + +EE EE V+P
Sbjct: 2139 LARKQRKLANKMRRMINKEEK--MTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRR 2196
Query: 1519 --KEKQTKPAEAPRLQLSSGFA-------WNVGLDSLTPALPPLA-----ESSDSEEDEK 1564
K K+ K + P+ + SS ++ ++SL L E + EE+E+
Sbjct: 2197 WRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEE 2256
Query: 1565 PHQATIKKSKKERELEKQKAEKELSRIEE 1593
+ +++ ++ER+ E++ EK++ + EE
Sbjct: 2257 REEEEVREEEEERKEEEEGEEKQVEKEEE 2285
Score = 34.3 bits (77), Expect = 1.2
Identities = 55/259 (21%), Positives = 105/259 (40%), Gaps = 55/259 (21%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRE 1472
+++K+EE+KT QK K+ +K +K+ + G+ + EM +E+ + E
Sbjct: 1386 EISKKEEKKTF-----QKSPKQGRKAVQKERKVGKIKREMTKEERDMSE----------E 1430
Query: 1473 CRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQ 1532
E + +E+V K+ K + E S +++ K+ +E + E +
Sbjct: 1431 VEEMATLEEKVVKQEGKLVMIERTPS-----WQDWKKAWDEWKQVHGETRK--------- 1476
Query: 1533 LSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEK--ELSR 1590
+W + L +E+EK HQA K S +E L++ K K E +
Sbjct: 1477 -----SWKAWKEEWEKRL--------LQEEEKLHQAGEKLSPEEEMLQEDKKLKWEEWKQ 1523
Query: 1591 IEEALMDPGRQPESADDFDRLVLSSPNS-----SILWLQYMAFHLQ------ATEIEKAR 1639
+ E ++ + + D + + L S + H+Q ++AR
Sbjct: 1524 VWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRAR 1583
Query: 1640 AVAERALKTISFREEQEKL 1658
A +RA + +E+EKL
Sbjct: 1584 AEKKRAQEERKLAQEEEKL 1602
Score = 32.7 bits (73), Expect = 3.4
Identities = 44/200 (22%), Positives = 79/200 (39%), Gaps = 44/200 (22%)
Query: 1408 ASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQK 1467
A ++ +E + EE + K + R K+ ++G + E K Q + ++++
Sbjct: 2168 ARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKE---KFSSQVDEVESEE 2224
Query: 1468 RGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAE 1527
E E E K+ LS E++ RE +EE EE V +E++ K E
Sbjct: 2225 HFSEEMESLLDELE------KQESLSSEEEE-----EREEEEEREEEEVREEEEERKEEE 2273
Query: 1528 APRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKE 1587
+ + EE+EK KK KKE++ E+ + ++E
Sbjct: 2274 EGE-----------------------EKQVEKEEEEK------KKKKKEKKKEEVQEKEE 2304
Query: 1588 LSRIEEALMDPGRQPESADD 1607
+ +E +M + ES D
Sbjct: 2305 VFEEKEEIMSE-EETESLSD 2323
>gi|169172639 PREDICTED: similar to U5 snRNP-associated 102 kDa
protein [Homo sapiens]
Length = 406
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/200 (18%), Positives = 81/200 (40%), Gaps = 7/200 (3%)
Query: 1610 RLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLEN 1669
R V P + +LWL A ++ AR++ ++F+ +W+A + LE+
Sbjct: 64 RAVAHCPKAEVLWLMGAKSKWLAGDVPAARSIL-----ALAFQANPNSEEIWLAAVKLES 118
Query: 1670 MYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWI 1729
E ++ +A +VF+ + + + A +L L+ + +W+
Sbjct: 119 ENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWM 178
Query: 1730 KYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789
G ++ + + L+ P + ++ ++LE ++G RA+AI E +
Sbjct: 179 MKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLL--LSRLEEKIGQLTRARAILEKSRL 236
Query: 1790 TYPKRTDVWSVYIDMTIKHG 1809
PK +W + + + G
Sbjct: 237 KNPKNPGLWLESVRLEYRAG 256
Score = 35.0 bits (79), Expect = 0.69
Identities = 24/123 (19%), Positives = 51/123 (41%), Gaps = 2/123 (1%)
Query: 1698 ADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPS 1757
AD + A +Y L+ F +K+VW++ F + +LQRA+ P
Sbjct: 12 ADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPK 71
Query: 1758 KEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDI 1817
E + ++ A+ ++ GD A++I P ++W + + ++ + R +
Sbjct: 72 AEVLWLMG--AKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRL 129
Query: 1818 FER 1820
+
Sbjct: 130 LAK 132
Score = 32.7 bits (73), Expect = 3.4
Identities = 39/202 (19%), Positives = 76/202 (37%), Gaps = 14/202 (6%)
Query: 1621 LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV 1680
LW+ Q +EKAR + LK +W+ L LE G +
Sbjct: 176 LWMMKGQIEEQKEMMEKAREAYNQGLKKCP-----HSTPLWLLLSRLEEKIGQLTRARAI 230
Query: 1681 FERAVQYNEPLK-VFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRS 1739
E++ N ++L + ++ A L + L+ +W + FL R
Sbjct: 231 LEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSE-AIFLEARP 289
Query: 1740 QAAASHRVLQRALECLPSKEH-VDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVW 1798
Q ++++ L EH V+ A+L + +A+ F T+ D W
Sbjct: 290 QRRT------KSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAW 343
Query: 1799 SVYIDMTIKHGSQKDVRDIFER 1820
+ + ++HG+++ ++ +R
Sbjct: 344 AFFYKFELQHGTEEQQEEVRKR 365
Score = 32.3 bits (72), Expect = 4.4
Identities = 36/168 (21%), Positives = 66/168 (39%), Gaps = 15/168 (8%)
Query: 1635 IEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVF 1694
+E ARA+ AL+ K +VW+ E +G++ESL + +RAV + +V
Sbjct: 21 LECARAIYAYALQVFP-----SKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEVL 75
Query: 1695 LHLADIYAKSE----KFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQR 1750
+ AKS+ A + + + +W+ + + R+L +
Sbjct: 76 WLMG---AKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAK 132
Query: 1751 ALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVW 1798
A P+ V K +LE+ + A+ + E L Y +W
Sbjct: 133 ARSSAPTAR---VFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLW 177
>gi|40807485 PRP6 pre-mRNA processing factor 6 homolog [Homo sapiens]
Length = 941
Score = 52.8 bits (125), Expect = 3e-06
Identities = 37/200 (18%), Positives = 81/200 (40%), Gaps = 7/200 (3%)
Query: 1610 RLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLEN 1669
R V P + +LWL A ++ AR++ ++F+ +W+A + LE+
Sbjct: 599 RAVAHCPKAEVLWLMGAKSKWLAGDVPAARSIL-----ALAFQANPNSEEIWLAAVKLES 653
Query: 1670 MYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWI 1729
E ++ +A +VF+ + + + A +L L+ + +W+
Sbjct: 654 ENDEYERARRLLAKARSSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWM 713
Query: 1730 KYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789
G ++ + + L+ P + ++ ++LE ++G RA+AI E +
Sbjct: 714 MKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLL--LSRLEEKIGQLTRARAILEKSRL 771
Query: 1790 TYPKRTDVWSVYIDMTIKHG 1809
PK +W + + + G
Sbjct: 772 KNPKNPGLWLESVRLEYRAG 791
Score = 41.2 bits (95), Expect = 0.010
Identities = 114/600 (19%), Positives = 226/600 (37%), Gaps = 92/600 (15%)
Query: 1330 YVGSIQPHGVFFRLGPSVVGLARYSHVSQHSPSKKALYNKHLPEGKLLTARVLRLNHQKN 1389
++G P G LG G S + + + ++H P GK ++ N +
Sbjct: 8 FLGMPAPLGYVPGLGRGATGFTTRSDIGPARDANDPVDDRHAPPGKRTVGDQMKKNQAAD 67
Query: 1390 LVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERD----QKGEKKNQKRNEKKNQK 1445
+ DT + G L + + EE D ++ +++R E++ Q+
Sbjct: 68 DDDEDL--NDTNYDEF--NGYAGSLFSSGPYEKDDEEADAIYAALDKRMDERRKERREQR 123
Query: 1446 GQEEVEMPSKEKQQPQKPQAQ-KRGGRECRES--------GSEQERVSKKPKKAGLSEED 1496
+EE+E E+ + Q+ + KR E E G + + + P+ L+
Sbjct: 124 EKEEIEKYRMERPKIQQQFSDLKRKLAEVTEEEWLSIPEVGDARNKRQRNPRYEKLTPVP 183
Query: 1497 DSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRL-QLSSGFAWNVGLDSLTPALPP--- 1552
DS + + G+ T+V P++ Q P L++ + + +TP
Sbjct: 184 DSFFAKHLQTGE---NHTSVDPRQTQFGGLNTPYPGGLNTPYPGGMTPGLMTPGTGELDM 240
Query: 1553 --------------LAESSDSEEDE----------------KPHQATIKKSKKERELEKQ 1582
L++ SDS + H I KK R L K
Sbjct: 241 RKIGQARNTLMDMRLSQVSDSVSGQTVVDPKGYLTDLNSMIPTHGGDINDIKKARLLLKS 300
Query: 1583 KAEKE---------LSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQAT 1633
E +R+EE G+ + + + P S +WL+ A LQ
Sbjct: 301 VRETNPHHPPAWIASARLEEV---TGKLQVARNLIMKGTEMCPKSEDVWLE--AARLQPG 355
Query: 1634 EIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKV 1693
+ A+AV +A+ R + + +++ LE +++ +V +A+++ P V
Sbjct: 356 --DTAKAVVAQAV-----RHLPQSVRIYIRAAELETDIRAKK---RVLRKALEH-VPNSV 404
Query: 1694 FLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALE 1753
L A + + E+ ++A + +R ++ +W+ L R + +VL +A E
Sbjct: 405 RLWKAAV--ELEEPEDARIMLSRAVECCPTSVELWLA----LARLETYENARKVLNKARE 458
Query: 1754 CLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPK-----RTDVWSVYIDMTIKH 1808
+P+ H+ + A A+LE G+ + + I + +++ + W + +
Sbjct: 459 NIPTDRHIWITA--AKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRA 516
Query: 1809 GSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKALEYVEAKSSV 1868
GS + + VI + + + K + D H + +A+ A AL+ +K SV
Sbjct: 517 GSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSV 576
Score = 40.0 bits (92), Expect = 0.021
Identities = 44/244 (18%), Positives = 100/244 (40%), Gaps = 17/244 (6%)
Query: 1624 QYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFER 1683
Q + +++A E+E +R L+ + + +W A + LE ++ L++ E
Sbjct: 371 QSVRIYIRAAELETDIRAKKRVLRK-ALEHVPNSVRLWKAAVELEEPEDARIMLSRAVEC 429
Query: 1684 AVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRSQAAA 1743
P V L LA A+ E ++ A ++ N+ + ++ +WI
Sbjct: 430 C-----PTSVELWLA--LARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQM 482
Query: 1744 SHRVLQRALECLPSKE---HVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTD---V 1797
+++ RA+ L + + + + A+ + G +A+ + + D
Sbjct: 483 VEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHT 542
Query: 1798 WSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAK 1857
W D + H + + R I+ + + + K + + R +EK HGT + ++A+ +
Sbjct: 543 WMEDADSCVAHNALECARAIYAYALQVFPSKKSV---WLRAAYFEKNHGTRESLEALLQR 599
Query: 1858 ALEY 1861
A+ +
Sbjct: 600 AVAH 603
Score = 33.1 bits (74), Expect = 2.6
Identities = 41/213 (19%), Positives = 80/213 (37%), Gaps = 18/213 (8%)
Query: 1616 PNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQE 1675
PNS LW + + E E AR + RA++ E +W+AL LE +++
Sbjct: 401 PNSVRLWKAAV----ELEEPEDARIMLSRAVECCPTSVE-----LWLALARLETYENARK 451
Query: 1676 SLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQE-----KAVWIK 1730
L K E +++ A + + Q ++ +R + R + WI+
Sbjct: 452 VLNKARENIPTDRH---IWITAAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQ 508
Query: 1731 YGAFLLRRSQAAASHRVLQRALEC-LPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789
R A V++ + + ++ + A E A+AI+ L
Sbjct: 509 DAEECDRAGSVATCQAVMRAVIGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQ 568
Query: 1790 TYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVI 1822
+P + VW HG+++ + + +R +
Sbjct: 569 VFPSKKSVWLRAAYFEKNHGTRESLEALLQRAV 601
Score = 32.7 bits (73), Expect = 3.4
Identities = 37/181 (20%), Positives = 70/181 (38%), Gaps = 15/181 (8%)
Query: 1622 WLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVF 1681
W++ + +E ARA+ AL+ K +VW+ E +G++ESL +
Sbjct: 543 WMEDADSCVAHNALECARAIYAYALQVFP-----SKKSVWLRAAYFEKNHGTRESLEALL 597
Query: 1682 ERAVQYNEPLKVFLHLADIYAKSE----KFQEAGELYNRMLKRFRQEKAVWIKYGAFLLR 1737
+RAV + +V + AKS+ A + + + +W+
Sbjct: 598 QRAVAHCPKAEVLWLMG---AKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESE 654
Query: 1738 RSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDV 1797
+ + R+L +A P+ V K +LE+ + A+ + E L Y +
Sbjct: 655 NDEYERARRLLAKARSSAPTAR---VFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKL 711
Query: 1798 W 1798
W
Sbjct: 712 W 712
Score = 32.7 bits (73), Expect = 3.4
Identities = 39/202 (19%), Positives = 76/202 (37%), Gaps = 14/202 (6%)
Query: 1621 LWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKV 1680
LW+ Q +EKAR + LK +W+ L LE G +
Sbjct: 711 LWMMKGQIEEQKEMMEKAREAYNQGLKKCP-----HSTPLWLLLSRLEEKIGQLTRARAI 765
Query: 1681 FERAVQYNEPLK-VFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFLLRRS 1739
E++ N ++L + ++ A L + L+ +W + FL R
Sbjct: 766 LEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQECPNSGILWSE-AIFLEARP 824
Query: 1740 QAAASHRVLQRALECLPSKEH-VDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRTDVW 1798
Q ++++ L EH V+ A+L + +A+ F T+ D W
Sbjct: 825 QRRT------KSVDALKKCEHDPHVLLAVAKLFWSQRKITKAREWFHRTVKIDSDLGDAW 878
Query: 1799 SVYIDMTIKHGSQKDVRDIFER 1820
+ + ++HG+++ ++ +R
Sbjct: 879 AFFYKFELQHGTEEQQEEVRKR 900
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 52.8 bits (125), Expect = 3e-06
Identities = 67/290 (23%), Positives = 114/290 (39%), Gaps = 46/290 (15%)
Query: 1393 LSFLPGDTGKPDVLSASLEGQLTKQEERKTEAE-ERDQKGEKKNQKRNEKKNQKGQEEVE 1451
+S L G PD A G T QEE ++ AE +D+ GE+ K EE E
Sbjct: 581 ISSLFGGGTTPD---AKENGTDTVQEEEESPAEGSKDEPGEQVELK----------EEAE 627
Query: 1452 MPSKEKQQPQKPQ----AQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREG 1507
P ++ QP P+ A G + + ++ K +KA EG
Sbjct: 628 APVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGP-----------EG 676
Query: 1508 KEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQ 1567
A E EK+ KPA R+ +G++ + LP L E ++ +K
Sbjct: 677 VAPAPE-----GEKKQKPARKRRM------VEEIGVELVVLDLPDLPEDKLAQSVQKLQD 725
Query: 1568 ATIKK-SKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYM 1626
T++ K+ERE E + ++ L P Q S ++ + +++ WL+
Sbjct: 726 LTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDE 785
Query: 1627 AFHLQATEIEKARAVAERALKTISFREEQ-----EKLNVWVALLNLENMY 1671
+++ A + + + FR E+ E+L+ LLN +M+
Sbjct: 786 GVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMF 835
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 52.8 bits (125), Expect = 3e-06
Identities = 67/290 (23%), Positives = 114/290 (39%), Gaps = 46/290 (15%)
Query: 1393 LSFLPGDTGKPDVLSASLEGQLTKQEERKTEAE-ERDQKGEKKNQKRNEKKNQKGQEEVE 1451
+S L G PD A G T QEE ++ AE +D+ GE+ K EE E
Sbjct: 581 ISSLFGGGTTPD---AKENGTDTVQEEEESPAEGSKDEPGEQVELK----------EEAE 627
Query: 1452 MPSKEKQQPQKPQ----AQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREG 1507
P ++ QP P+ A G + + ++ K +KA EG
Sbjct: 628 APVEDGSQPPPPEPKGDATPEGEKATEKENGDKSEAQKPSEKAEAGP-----------EG 676
Query: 1508 KEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQ 1567
A E EK+ KPA R+ +G++ + LP L E ++ +K
Sbjct: 677 VAPAPE-----GEKKQKPARKRRM------VEEIGVELVVLDLPDLPEDKLAQSVQKLQD 725
Query: 1568 ATIKK-SKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYM 1626
T++ K+ERE E + ++ L P Q S ++ + +++ WL+
Sbjct: 726 LTLRDLEKQEREKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDE 785
Query: 1627 AFHLQATEIEKARAVAERALKTISFREEQ-----EKLNVWVALLNLENMY 1671
+++ A + + + FR E+ E+L+ LLN +M+
Sbjct: 786 GVGATTVMLKEKLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMF 835
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 52.0 bits (123), Expect = 5e-06
Identities = 74/333 (22%), Positives = 142/333 (42%), Gaps = 41/333 (12%)
Query: 1406 LSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEK---KNQKGQEEVEMPSKEKQQPQK 1462
L+ E ++ +QEE+ E EE+ Q+ E+K +++ EK + +K + + EM EK++ +
Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEM-MWEKEEKMR 352
Query: 1463 PQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQ 1522
Q + +E + E+ K+ K L E+ + +E K + EE +++Q
Sbjct: 353 RQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 412
Query: 1523 TKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDS--EEDEKPHQATIKKSKKERELE 1580
+ A+ R + + + + E ++EK H+ +K RE E
Sbjct: 413 EQEAKMWRQE-----------EKIREQEEKIREQEKKMWRQEEKIHE-----QEKIREEE 456
Query: 1581 KQKAEKELSRIEEALMDP---GRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEK 1637
K++ ++E+ R EE + + RQ E + +++ +W Q H Q +I +
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI---RKQEEKVWRQEEKMHDQEEKIRE 513
Query: 1638 ARAVAERALKTISFREEQEKLNVW-VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLH 1696
R + I RE++EK+ + E M QE E +Q E ++
Sbjct: 514 QEEKMWRQEEKI--REQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMR---- 567
Query: 1697 LADIYAKSEKFQEAGELYNRMLKRFR-QEKAVW 1728
+ EK +E E ++ R QE+ +W
Sbjct: 568 -----RQEEKIREQEEKIREQKEKIREQEEKIW 595
Score = 46.2 bits (108), Expect = 3e-04
Identities = 45/196 (22%), Positives = 90/196 (45%), Gaps = 23/196 (11%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ + EE+ ++ E+K ++ EK ++ ++ E K ++Q + Q Q+
Sbjct: 494 EEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKM 553
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPR 1530
E E EQE++ ++ +K + E+++ + RE KE+ E E++ K E
Sbjct: 554 GEQEEKMQEQEKMRRQEEK--IREQEEKI-----REQKEKIREQEEKIWEQEEKIREQEE 606
Query: 1531 -LQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELS 1589
+Q W E E++EK + K ++E ++ +Q E L
Sbjct: 607 MMQEQEEKMWE-------------QEEKMCEQEEKMQEQEEKMRRQEEKMWEQ--EVRLR 651
Query: 1590 RIEEALMDPGRQPESA 1605
+ EE + + E+A
Sbjct: 652 QQEEKMQEHQEHLEAA 667
Score = 35.0 bits (79), Expect = 0.69
Identities = 36/181 (19%), Positives = 77/181 (42%), Gaps = 21/181 (11%)
Query: 1417 QEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRES 1476
++E+ + EE+ + E+K + EK ++ ++ K ++Q +K + Q+ RE E
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545
Query: 1477 GSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSG 1536
EQE + ++ +E + RE +E+ E +E++ K E
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQ- 604
Query: 1537 FAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALM 1596
E E++EK + K ++E ++++Q E+++ R EE +
Sbjct: 605 ------------------EEMMQEQEEKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMW 644
Query: 1597 D 1597
+
Sbjct: 645 E 645
Score = 32.0 bits (71), Expect = 5.8
Identities = 54/294 (18%), Positives = 116/294 (39%), Gaps = 40/294 (13%)
Query: 1440 EKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSL 1499
++KN K QE++++ EK + Q + + E + Q+++ + G ++
Sbjct: 220 KEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLG---KELQS 276
Query: 1500 VDVYYREGKEEAEETNVLPKEKQTKP-AEAPRLQLSSGFAWNVGLDSLTPALPPLAESSD 1558
V + EE E N L ++++ K + ++Q W + + E
Sbjct: 277 VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ-----EWEEKIQEQEEKIREQEEKIR 331
Query: 1559 SEEDEKPHQATI--KKSKKERELEKQKAEKE--LSRIEEALMDPGRQPESADDFDRLVLS 1614
+E++ Q + +K +K R E+ EKE + R+EE + + + ++
Sbjct: 332 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEE------- 384
Query: 1615 SPNSSILWLQYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQ 1674
+ E EK R E+ + RE++++ + E Q
Sbjct: 385 ----------------KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 428
Query: 1675 ESLTKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVW 1728
E + E+ + E +H + + EK QE E++ R ++ R+++ +W
Sbjct: 429 EEKIREQEKKMWRQEEK---IHEQEKIREEEKRQEQEEMW-RQEEKIREQEEIW 478
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 52.0 bits (123), Expect = 5e-06
Identities = 66/330 (20%), Positives = 135/330 (40%), Gaps = 33/330 (10%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E Q+ +QEE+ E EE+ ++ E+K ++ E+ ++ ++ E K + Q ++ Q
Sbjct: 347 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 406
Query: 1471 RECRESGSEQER----VSKKPKKAGLSEEDDSLVDVYYREGKEE--AEETNVLPKEKQTK 1524
RE E EQE+ V K ++ + E++ D + +EE E + +E++T
Sbjct: 407 REKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETM 466
Query: 1525 PAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKA 1584
+ ++Q W E++EK Q +KE+ E++K
Sbjct: 467 REQEEKMQKQEENMW--------------------EQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 1585 EKELSRI---EEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEI--EKAR 1639
+++ +I EE + D R +W Q Q ++ ++ R
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 1640 AVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLAD 1699
+ + +++EK+ + E +E + + E +Q E K+
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEE-KMQEQEEK 625
Query: 1700 IYAKSEKFQEAGE-LYNRMLKRFRQEKAVW 1728
++ + EK QE E ++ + K + QE+ +W
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Score = 51.6 bits (122), Expect = 7e-06
Identities = 67/333 (20%), Positives = 145/333 (43%), Gaps = 67/333 (20%)
Query: 1403 PDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEK-KNQKG---QEEVEMPSKEK- 1457
P V + +L+ ++ +QEE E E++ +K E+K ++ E+ + Q+G ++E +M +EK
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKR 322
Query: 1458 --QQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETN 1515
+Q ++ + Q++ RE +E ++E++ ++ +K EE + +E K +E
Sbjct: 323 LREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEE-----KMREQEEKMWRQEER 377
Query: 1516 VLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKK 1575
+ +EKQ + E +++ W E+DE+ + + ++
Sbjct: 378 LWEQEKQMREQE-QKMRDQEERMW--------------------EQDERLREKEERMREQ 416
Query: 1576 ER---ELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQA 1632
E+ ++EK + EK++ E+ D Q E + +R+
Sbjct: 417 EKMWEQVEKMREEKKMQEQEKKTRD---QEEKMQEEERI--------------------- 452
Query: 1633 TEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLK 1692
E EK E ++ + ++++ N+W E K++E+ + K
Sbjct: 453 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 1693 VFLHLADIYAKSEKFQEAGELYNRMLKRFRQEK 1725
I+ + EK ++ E++ + K +RQEK
Sbjct: 513 -------IWEQEEKIRDQEEMWGQEKKMWRQEK 538
Score = 47.0 bits (110), Expect = 2e-04
Identities = 67/321 (20%), Positives = 134/321 (41%), Gaps = 47/321 (14%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E + +QEE+ E EE+ Q+ E+K ++ EK ++ ++ E K +Q +K Q+R
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR-L 660
Query: 1471 RECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPR 1530
E +E E E++ ++ K + E+++ + + E K + +E +EK +
Sbjct: 661 PEQKEKLWEHEKMQEQEK---MQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREE----- 712
Query: 1531 LQLSSGFAWNVGLDSLTPALPPLAESSD--SEEDEKPHQATIKKSKKERELEKQKAEKEL 1588
+S+ + E + E++EK + K ++E E+ +Q E+++
Sbjct: 713 -------------ESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQ--EEKM 757
Query: 1589 SRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEI----EKARAVAER 1644
EE + + R PE + I W Q Q ++ EK R E+
Sbjct: 758 WEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKI-WEQEEKMRDQEEKMRGQEEKMRGQEEK 816
Query: 1645 ALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKS 1704
R ++EK+ W E M+G +E + E+ E ++ + +
Sbjct: 817 ------MRGQEEKM--WG---QEEKMWGQEEKMWGQEEKMWGQEEKME-----EKMQGQE 860
Query: 1705 EKFQEAGELYNRMLKRFRQEK 1725
EK +E E ++ R+++
Sbjct: 861 EKMREQEEKMRGQEEKMREQE 881
Score = 44.3 bits (103), Expect = 0.001
Identities = 71/340 (20%), Positives = 137/340 (40%), Gaps = 39/340 (11%)
Query: 1415 TKQEERKTEAEERDQKGEKK------NQKRNEKKNQKGQEEV-EMPSKEKQQPQKPQAQK 1467
T+ +E K + EER ++ EKK + E+K QK +E + E KE QQ + P+ QK
Sbjct: 439 TRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE-QK 497
Query: 1468 RGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAE 1527
E + ++E++ ++ +K EE +R+ K +E + +E++ + E
Sbjct: 498 EKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557
Query: 1528 APRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKE 1587
W+ ++ D EE + + ++ KK RE E+ E+E
Sbjct: 558 QK--------MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 1588 LSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALK 1647
E+ + Q + +++ +W Q Q ++ + + + E+ K
Sbjct: 610 EKMQEQ---EEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEK 666
Query: 1648 TISFR--EEQEKL-----NVWVALLNLENMYGSQESLT----------KVFERAVQYNEP 1690
+EQEK+ +W +E QE T + ER + E
Sbjct: 667 LWEHEKMQEQEKMQEQEEKIW-EQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Query: 1691 LKVFLHLAD-IYAKSEKFQE-AGELYNRMLKRFRQEKAVW 1728
++ + + + EK QE E++ + K + QE+ +W
Sbjct: 726 EEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMW 765
Score = 41.2 bits (95), Expect = 0.010
Identities = 55/274 (20%), Positives = 116/274 (42%), Gaps = 45/274 (16%)
Query: 1415 TKQEERKT-EAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGREC 1473
T+++E+KT + EE+ ++ E+ R +K + +EE+ +EK Q Q+ + Q++ +
Sbjct: 571 TQEQEKKTWDQEEKMREEER---MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW 627
Query: 1474 RESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQ-----TKPAEA 1528
+ QE+ K + E+++ + E +E+ E LP++K+ K E
Sbjct: 628 EQEEKMQEQEEK------MWEQEEKM-----WEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 1529 PRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQ-KAEKE 1587
++Q W + + + +E + Q +++ + RE EK+ + E+E
Sbjct: 677 EKMQEQEEKIWE---------QEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE 727
Query: 1588 LSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERALK 1647
+ R +E M Q E + +W Q Q ++ + + + E+ K
Sbjct: 728 MMREQEEKMQ--EQEEKMQE---------QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK 776
Query: 1648 TISFREEQEKLNVWVALLNL----ENMYGSQESL 1677
+ QE+ +W + E M G +E +
Sbjct: 777 LWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKM 810
Score = 32.0 bits (71), Expect = 5.8
Identities = 25/101 (24%), Positives = 50/101 (49%), Gaps = 5/101 (4%)
Query: 1413 QLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRE 1472
++ +QEE+ + EE+ + E+K + + EK +GQEE +EK Q+ +K G+E
Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKMRGQEEK--MRGQEEKMWGQEEKMWGQE---EKMWGQE 842
Query: 1473 CRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEE 1513
+ G E++ K + E + + + +E+ E+
Sbjct: 843 EKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEK 883
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 123
Score = 52.0 bits (123), Expect = 5e-06
Identities = 33/107 (30%), Positives = 54/107 (50%), Gaps = 1/107 (0%)
Query: 1418 EERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESG 1477
EE + E E+ ++ EK+ +KR EK+ +K +E E KEK++ +K + +KR ++ E
Sbjct: 17 EETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEK-RKEKEEEEKKRKRKRKKKKEEEER 75
Query: 1478 SEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTK 1524
E+E ++ K+ EE R KEE EE + K K
Sbjct: 76 EEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKK 122
Score = 48.5 bits (114), Expect = 6e-05
Identities = 22/75 (29%), Positives = 48/75 (64%), Gaps = 2/75 (2%)
Query: 1415 TKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECR 1474
TK+ E++ E EE ++K ++K +K+ E++ ++ +EE E +EK++ +K + ++R ++ R
Sbjct: 46 TKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEE--EEEKEEEEKEEGRRRKKKKKR 103
Query: 1475 ESGSEQERVSKKPKK 1489
E+E KK ++
Sbjct: 104 RRKEEEEEKKKKRRR 118
Score = 45.1 bits (105), Expect = 7e-04
Identities = 19/79 (24%), Positives = 47/79 (59%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E + K++++KT+ E+ ++ E++ +KR K+ +K +EE +E+++ +K + +K G
Sbjct: 35 EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEG 94
Query: 1471 RECRESGSEQERVSKKPKK 1489
R ++ + + ++ KK
Sbjct: 95 RRRKKKKKRRRKEEEEEKK 113
Score = 44.7 bits (104), Expect = 9e-04
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 9/96 (9%)
Query: 1411 EGQLTKQEERKT------EAEERDQKGEKKNQKRNEKKNQKGQEEVEMP---SKEKQQPQ 1461
E + T++EE K E+R +K +KK K EK+ +K +EE + K+K++ +
Sbjct: 15 ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEE 74
Query: 1462 KPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDD 1497
+ + ++ E E E+ R KK KK EE++
Sbjct: 75 REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 40.8 bits (94), Expect = 0.013
Identities = 30/111 (27%), Positives = 60/111 (54%), Gaps = 12/111 (10%)
Query: 1416 KQEERKTEAEERDQKGEKKNQKRNE-KKNQKGQEEVEMPSKEKQQPQK-PQAQKRGGREC 1473
K++++K E EE ++ E + ++ E K+ +K +E+ KEK++ +K + +KR +E
Sbjct: 2 KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEK----RKEKEKKKKTKETEKRKEKEE 57
Query: 1474 RESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTK 1524
E +++R KK ++ EE++ E KEE E+ ++K+ K
Sbjct: 58 EEKKRKRKRKKKKEEEEREEEEEEE------EEEKEEEEKEEGRRRKKKKK 102
Score = 40.8 bits (94), Expect = 0.013
Identities = 41/175 (23%), Positives = 72/175 (41%), Gaps = 65/175 (37%)
Query: 1416 KQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRE 1475
K+E +TE E ++ E+K KR EK+ +K +E KEK++ K + +KR +E
Sbjct: 7 KKETEETEETEETEEEEEKEGKRKEKRKEKRKE------KEKKKKTK-ETEKRKEKE--- 56
Query: 1476 SGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSS 1535
E+E+ K+ +K EE+ RE +EE EE
Sbjct: 57 ---EEEKKRKRKRKKKKEEEE--------REEEEEEEE---------------------- 83
Query: 1536 GFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSR 1590
+ +E+E+ + +K KK+R ++++ EK+ R
Sbjct: 84 ----------------------EEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKR 116
Score = 39.7 bits (91), Expect = 0.028
Identities = 24/97 (24%), Positives = 51/97 (52%), Gaps = 5/97 (5%)
Query: 1426 ERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSK 1485
++ +K +K+ ++ E + + +EE E KEK++ ++ + +K+ + E E+E K
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 1486 KPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQ 1522
K K+ ++++ RE +EE EE +EK+
Sbjct: 61 KRKRKRKKKKEEE-----EREEEEEEEEEEKEEEEKE 92
Score = 37.0 bits (84), Expect = 0.18
Identities = 31/153 (20%), Positives = 61/153 (39%), Gaps = 36/153 (23%)
Query: 1438 RNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDD 1497
+ +KK +K EE E + +++ +K +K +E R+ ++++ + K+
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR-------- 52
Query: 1498 SLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESS 1557
KE+ EE ++++ K E R + E
Sbjct: 53 ----------KEKEEEEKKRKRKRKKKKEEEEREEEEE------------------EEEE 84
Query: 1558 DSEEDEKPHQATIKKSKKERELEKQKAEKELSR 1590
+ EE+EK KK KK R E+++ +K+ R
Sbjct: 85 EKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRR 117
Score = 33.9 bits (76), Expect = 1.5
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 30/116 (25%)
Query: 1481 ERVSKKPKKAGLSEEDDSLVDVYYREGKEEA---EETNVLPKEKQTKPAEAPRLQLSSGF 1537
++ KK K+ +EE + + +EGK + E+ K+K+TK E
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE---------- 50
Query: 1538 AWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEE 1593
+ + EE+EK + KK K+E E E+++ E+E + EE
Sbjct: 51 -----------------KRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEE 89
Score = 33.5 bits (75), Expect = 2.0
Identities = 13/52 (25%), Positives = 32/52 (61%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQK 1462
E + ++EE + E +E ++K E + +K+ +K+ +K +EE + + ++ +K
Sbjct: 72 EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 51.6 bits (122), Expect = 7e-06
Identities = 64/272 (23%), Positives = 114/272 (41%), Gaps = 24/272 (8%)
Query: 1396 LPGDTGKPDVLSASLE----GQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVE 1451
LP DT P L+ + K E+ + EAE R ++ E++ +++ E + Q+ +
Sbjct: 706 LPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 765
Query: 1452 MPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEA 1511
+E+++ ++ + +R E EQE ++ ++ EE+ + R +E
Sbjct: 766 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQRE----EEERQQQEEALRRLEERR 821
Query: 1512 EETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIK 1571
E +E++ K E R Q W A L E+ E+E +
Sbjct: 822 RE-----EEERRKQEELLRKQEEEAAKW---AREEEEAQRRLEENRLRMEEEAARLRHEE 873
Query: 1572 KSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQY---MAF 1628
+ +K +ELE Q+ +KEL R + + R+ + +L SS W Q A
Sbjct: 874 EERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 932
Query: 1629 HLQAT----EIEKARAVAERALKTISFREEQE 1656
QAT EI+K ER L+ R+++E
Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRE 964
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 51.6 bits (122), Expect = 7e-06
Identities = 64/272 (23%), Positives = 114/272 (41%), Gaps = 24/272 (8%)
Query: 1396 LPGDTGKPDVLSASLE----GQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVE 1451
LP DT P L+ + K E+ + EAE R ++ E++ +++ E + Q+ +
Sbjct: 733 LPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 792
Query: 1452 MPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEA 1511
+E+++ ++ + +R E EQE ++ ++ EE+ + R +E
Sbjct: 793 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQRE----EEERQQQEEALRRLEERR 848
Query: 1512 EETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIK 1571
E +E++ K E R Q W A L E+ E+E +
Sbjct: 849 RE-----EEERRKQEELLRKQEEEAAKW---AREEEEAQRRLEENRLRMEEEAARLRHEE 900
Query: 1572 KSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQY---MAF 1628
+ +K +ELE Q+ +KEL R + + R+ + +L SS W Q A
Sbjct: 901 EERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 959
Query: 1629 HLQAT----EIEKARAVAERALKTISFREEQE 1656
QAT EI+K ER L+ R+++E
Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRE 991
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 51.6 bits (122), Expect = 7e-06
Identities = 64/272 (23%), Positives = 114/272 (41%), Gaps = 24/272 (8%)
Query: 1396 LPGDTGKPDVLSASLE----GQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVE 1451
LP DT P L+ + K E+ + EAE R ++ E++ +++ E + Q+ +
Sbjct: 712 LPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 771
Query: 1452 MPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEA 1511
+E+++ ++ + +R E EQE ++ ++ EE+ + R +E
Sbjct: 772 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQRE----EEERQQQEEALRRLEERR 827
Query: 1512 EETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIK 1571
E +E++ K E R Q W A L E+ E+E +
Sbjct: 828 RE-----EEERRKQEELLRKQEEEAAKW---AREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 1572 KSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQY---MAF 1628
+ +K +ELE Q+ +KEL R + + R+ + +L SS W Q A
Sbjct: 880 EERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 1629 HLQAT----EIEKARAVAERALKTISFREEQE 1656
QAT EI+K ER L+ R+++E
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRE 970
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 51.6 bits (122), Expect = 7e-06
Identities = 64/272 (23%), Positives = 114/272 (41%), Gaps = 24/272 (8%)
Query: 1396 LPGDTGKPDVLSASLE----GQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVE 1451
LP DT P L+ + K E+ + EAE R ++ E++ +++ E + Q+ +
Sbjct: 712 LPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRR 771
Query: 1452 MPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEA 1511
+E+++ ++ + +R E EQE ++ ++ EE+ + R +E
Sbjct: 772 QQEEERKRREEEELARRKQEEALRRQREQEIALRRQRE----EEERQQQEEALRRLEERR 827
Query: 1512 EETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIK 1571
E +E++ K E R Q W A L E+ E+E +
Sbjct: 828 RE-----EEERRKQEELLRKQEEEAAKW---AREEEEAQRRLEENRLRMEEEAARLRHEE 879
Query: 1572 KSKKERELEKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQY---MAF 1628
+ +K +ELE Q+ +KEL R + + R+ + +L SS W Q A
Sbjct: 880 EERKRKELEVQR-QKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTAC 938
Query: 1629 HLQAT----EIEKARAVAERALKTISFREEQE 1656
QAT EI+K ER L+ R+++E
Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRE 970
>gi|4557495 cleavage stimulation factor subunit 3 isoform 1 [Homo
sapiens]
Length = 717
Score = 51.6 bits (122), Expect = 7e-06
Identities = 54/231 (23%), Positives = 99/231 (42%), Gaps = 14/231 (6%)
Query: 1651 FREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQ--YNEPLKVFLHLADIYAKSEKFQ 1708
+ E+ KL +N ++ + + ++ERA+ + + ++ AD K++
Sbjct: 300 YLEQSSKLLAEKGDMNNAKLFSDEAA--NIYERAISTLLKKNMLLYFAYADYEESRMKYE 357
Query: 1709 EAGELYNRMLK-RFRQEKAVWIKYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKF 1767
+ +YNR+L V+I+Y F R + + ++A E ++ HV V A
Sbjct: 358 KVHSIYNRLLAIEDIDPTLVYIQYMKFARRAEGIKSGRMIFKKAREDTRTRHHVYVTA-- 415
Query: 1768 AQLEFQLG-DAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHL-S 1825
A +E+ D A IFE L Y + YID + R +FERV+ S
Sbjct: 416 ALMEYYCSKDKSVAFKIFELGLKKYGDIPEYVLAYIDYLSHLNEDNNTRVLFERVLTSGS 475
Query: 1826 LAPKRMKFFFKRYLDYEKQHGTEKDVQAVKAKAL-----EYVEAKSSVLED 1871
L P++ + R+L +E G + V+ + EY ++++L D
Sbjct: 476 LPPEKSGEIWARFLAFESNIGDLASILKVEKRRFTAFKEEYEGKETALLVD 526
Score = 33.1 bits (74), Expect = 2.6
Identities = 20/78 (25%), Positives = 37/78 (47%), Gaps = 12/78 (15%)
Query: 1771 EFQLGDAERAKAIFENTLSTYPKRTDVWSVYIDMTIKHGSQKDVRDIFER----VIHLSL 1826
E Q ++A+ +E ++ +P W +YI+ IK + V +F+R V+H+ L
Sbjct: 41 EAQNQPIDKARKTYERLVAQFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKVLHIDL 100
Query: 1827 APKRMKFFFKRYLDYEKQ 1844
+K YL Y ++
Sbjct: 101 --------WKCYLSYVRE 110
Score = 31.6 bits (70), Expect = 7.6
Identities = 21/96 (21%), Positives = 42/96 (43%), Gaps = 4/96 (4%)
Query: 1556 SSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQP--ESADDFDRLVL 1613
S D ++ K K E++LE+ + + I + + QP ++ ++RLV
Sbjct: 2 SGDGATEQAAEYVPEKVKKAEKKLEENPYDLDAWSI--LIREAQNQPIDKARKTYERLVA 59
Query: 1614 SSPNSSILWLQYMAFHLQATEIEKARAVAERALKTI 1649
P+S W Y+ ++A +K + +R L +
Sbjct: 60 QFPSSGRFWKLYIEAEIKAKNYDKVEKLFQRCLMKV 95
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 50.4 bits (119), Expect = 2e-05
Identities = 51/236 (21%), Positives = 107/236 (45%), Gaps = 29/236 (12%)
Query: 1375 KLLTARV-LRLNHQKNLVELSFLPGDTGKPDVLSASLEGQLTKQEERKTEAEERDQKGEK 1433
K +++R ++LN + +V S + KP S + ++ E++ E+++K E+
Sbjct: 3 KAISSRAAVKLNTELQMVSCSHI----SKPCTQRESERKKERREREKRKREREKERKRER 58
Query: 1434 -KNQKRNEKKNQKGQE-EVEMPSKEKQQPQKPQAQKRGGRECRESGSEQERVSKKPKKAG 1491
K +K+ KK ++G+E E + +EKQ+ ++ + ++R ++ ++ ++R ++ KK
Sbjct: 59 GKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKK 118
Query: 1492 LSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALP 1551
+E + RE K+ E K ++ K + + + G
Sbjct: 119 ERKERE-------RENKQRRERKR--KKRRKKKRRKERKREKERG------------KRE 157
Query: 1552 PLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSRIEEALMDPGRQPESADD 1607
+ EE EK + K+ KKERE K++ E++ R +E R+ + D
Sbjct: 158 RKRKKRKKEEREKKRERNRKERKKERE-RKERRERKKERKKERRKKKERKKDRKTD 212
Score = 42.4 bits (98), Expect = 0.004
Identities = 22/86 (25%), Positives = 50/86 (58%), Gaps = 3/86 (3%)
Query: 1416 KQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRE 1475
K+++R+ + +++K EK+ KR K+ ++ +EE E K++++ +K + ++R +E RE
Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEERE---KKRERNRKERKKERERKERRE 190
Query: 1476 SGSEQERVSKKPKKAGLSEEDDSLVD 1501
E+++ +K K+ + D D
Sbjct: 191 RKKERKKERRKKKERKKDRKTDRQTD 216
Score = 35.0 bits (79), Expect = 0.69
Identities = 16/69 (23%), Positives = 37/69 (53%)
Query: 1416 KQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGRECRE 1475
++ E+K E +++K E++ ++R E+K ++ +E + ++K + Q + R RE
Sbjct: 166 EEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225
Query: 1476 SGSEQERVS 1484
S + V+
Sbjct: 226 SAFNRVTVT 234
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 50.4 bits (119), Expect = 2e-05
Identities = 60/335 (17%), Positives = 149/335 (44%), Gaps = 38/335 (11%)
Query: 1403 PDVLSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQK 1462
P V + +L+ ++ +QEE E E++ +K E+K ++ E+ ++ + E K ++Q ++
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKR 284
Query: 1463 PQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEE--AEETNVLPKE 1520
+ Q++ RE + EQ+++ ++ ++ EE + RE +E+ +E + +E
Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344
Query: 1521 KQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELE 1580
KQ + E +++ W E+DE+ + + ++E+ E
Sbjct: 345 KQMREQE-QKMRDQEERMW--------------------EQDERLREKEERMREQEKMWE 383
Query: 1581 KQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARA 1640
+++ +E RI E + E+ + + + + +W Q + + ++
Sbjct: 384 QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN--MWEQ----EEKEWQQQRLPE 437
Query: 1641 VAERALKTISFREEQEKLNVW---VALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHL 1697
E+ + +E++EK +W + + E M+G ++ + + + Q ++ + +
Sbjct: 438 QKEKLWEQEKMQEQEEK--IWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 1698 AD----IYAKSEKFQEAGELYNRMLKRFRQEKAVW 1728
D ++ + E+ E E +R R++K +W
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Score = 45.4 bits (106), Expect = 5e-04
Identities = 42/194 (21%), Positives = 91/194 (46%), Gaps = 24/194 (12%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEK----KNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQ 1466
E ++ +Q+ER E EER ++ +K + + R EKK Q+ +++ ++ ++ ++ + +
Sbjct: 506 EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRER 565
Query: 1467 KRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPA 1526
++ RE E EQE ++ ++ + E+++ + + E +E EE +EK +
Sbjct: 566 EKKMREEEEMMREQEEKMQEQEEK-MREQEEKMWE--QEEKMQEQEEKMWEQEEKMWEQE 622
Query: 1527 EAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKEREL----EKQ 1582
E ++Q W E E++EK + K ++E ++ EK
Sbjct: 623 EEDKMQEQEEMMWE-------------QEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 1583 KAEKELSRIEEALM 1596
+ ++E R +E M
Sbjct: 670 QGQEEKMREQEEKM 683
Score = 43.5 bits (101), Expect = 0.002
Identities = 35/128 (27%), Positives = 64/128 (50%), Gaps = 11/128 (8%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEK-----KNQKGQEEVEMPSKEKQQPQ---- 1461
E + +QEE+ E EE+ + E+K +++ EK + +GQEE +EK Q Q
Sbjct: 631 EEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM 690
Query: 1462 KPQAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEK 1521
+ Q +K G+E + G E++ ++ K G E + + R+ KE+ +E +E+
Sbjct: 691 REQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREK--EERIRDQKEKMQERLPEHEER 748
Query: 1522 QTKPAEAP 1529
++P P
Sbjct: 749 CSEPCLPP 756
Score = 41.2 bits (95), Expect = 0.010
Identities = 44/195 (22%), Positives = 90/195 (46%), Gaps = 26/195 (13%)
Query: 1411 EGQLTKQEERKTEAEER----DQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQ 1466
E ++ QE++ + EER D++ +K ++ E+K QEE + ++ +K Q Q
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEE------KMREEKKTQEQ 545
Query: 1467 KRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPA 1526
++ + E E+ER+ ++ KK + EE++ + RE +E+ +E +E++ K
Sbjct: 546 EKKTWDQEEKMREEERMREREKK--MREEEEMM-----REQEEKMQEQEEKMREQEEKMW 598
Query: 1527 E-APRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKEREL----EK 1581
E ++Q W + E E++E + K ++E ++ EK
Sbjct: 599 EQEEKMQEQEEKMW----EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 1582 QKAEKELSRIEEALM 1596
+ ++E R +E M
Sbjct: 655 MREQEEKMREQEEKM 669
Score = 40.4 bits (93), Expect = 0.016
Identities = 67/336 (19%), Positives = 133/336 (39%), Gaps = 51/336 (15%)
Query: 1411 EGQLTKQEE---------RKTEAEERDQKGEKKNQK--RNEKKNQKGQEEVEMPSKEKQQ 1459
EG++ +QEE R+ E E R+Q+ E + QK R +++ + QEE +EK +
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMR 327
Query: 1460 PQKPQAQKRGGRECRESGSEQERVSK-KPKKAGLSEEDDSLVDVYYREGKEEAEETNVLP 1518
Q+ + ++ R + +E+ K + ++ + E+D+ L RE +E E +
Sbjct: 328 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL-----REKEERMREQEKM- 381
Query: 1519 KEKQTKPAEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERE 1578
E++ K E R++ E EE+E + K K+E
Sbjct: 382 WEQEEKMQEEERIR--------------------EREKKMREEEETMREQEEKMQKQEEN 421
Query: 1579 L----EKQKAEKELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATE 1634
+ EK+ ++ L +E L + + E + + +W Q Q
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 1635 IEKARAVAERALKTISFREEQEKL-----NVWVALLNLENMYGSQESLTKVFERAVQYNE 1689
E+ + E+ K R++++K+ +W L K++++ + E
Sbjct: 482 REQEDQMWEQEEK---MRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE 538
Query: 1690 PLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEK 1725
K + + EK +E + R K+ R+E+
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMRERE-KKMREEE 573
Score = 39.3 bits (90), Expect = 0.036
Identities = 34/187 (18%), Positives = 83/187 (44%), Gaps = 14/187 (7%)
Query: 1412 GQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGGR 1471
GQ K ++ E+ DQ E++ + R++++ QEE E+ + ++ + +++
Sbjct: 470 GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKM 529
Query: 1472 ECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAE-APR 1530
+E +E+ +++ +K +E+ + RE +++ E + +E++ K E +
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEK 589
Query: 1531 LQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKELSR 1590
++ W E E++EK + K ++E E + Q+ E+ +
Sbjct: 590 MREQEEKMWE-------------QEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE 636
Query: 1591 IEEALMD 1597
EE + +
Sbjct: 637 QEEKMQE 643
Score = 39.3 bits (90), Expect = 0.036
Identities = 43/194 (22%), Positives = 85/194 (43%), Gaps = 19/194 (9%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQ--AQKR 1468
E ++ +QEE+ E EE+ + E+K Q++ EK ++ ++ E ++K Q Q+ Q+
Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEE 639
Query: 1469 GGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKPAEA 1528
+E E EQE ++ ++ + E+++ + E E EE +EK + E
Sbjct: 640 KMQEQEEKMWEQEEKMREQEEK-MREQEEKMQG--QEEKMREQEEKMQGQEEKMREQEEK 696
Query: 1529 PRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAEKEL 1588
R Q W E +E++ Q +++ ++ +K+K ++ L
Sbjct: 697 MRGQEEK--MWG------------QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Query: 1589 SRIEEALMDPGRQP 1602
EE +P P
Sbjct: 743 PEHEERCSEPCLPP 756
>gi|229577238 tetratricopeptide repeat domain 18 [Homo sapiens]
Length = 1121
Score = 50.1 bits (118), Expect = 2e-05
Identities = 47/185 (25%), Positives = 79/185 (42%), Gaps = 15/185 (8%)
Query: 1624 QYMAFHLQATEIEKARAVAERALKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFER 1683
+Y AF Q + V ++ LKT SF E QE+L +++ L + + +L +
Sbjct: 565 KYFAFKEQLKHAV-VKIVRDKYLKTTSF-ESQEELQTFISELYVFLVDQMHVALNQTMPD 622
Query: 1684 AVQ--------YNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKRFRQEKAVWIKYGAFL 1735
VQ +E L++F A++ +E F+ A Y L R Q W+ YGAF
Sbjct: 623 DVQGTVATIYTSSEQLQLFAFEAEV---NENFEMAAAYYKERLVREPQNLDHWLDYGAFC 679
Query: 1736 LRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLSTYPKRT 1795
L + Q+AL ++ H+ + L L + E+A+ FE+ P
Sbjct: 680 LLTEDNIKAQECFQKALSL--NQSHIHSLLLCGVLAVLLENYEQAEIFFEDATCLEPTNV 737
Query: 1796 DVWSV 1800
W++
Sbjct: 738 VAWTL 742
Score = 31.6 bits (70), Expect = 7.6
Identities = 38/185 (20%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 1673 SQESL--TKVFERAVQYNEPLKVFLHLADIYAKSEKFQEAGELYNRMLKR-FRQEKAVWI 1729
SQE + T+ ++ ++ +P F+ ++ K Q++ L + L Q +++
Sbjct: 839 SQEPILTTQTWDPSIS-QKPSNTFIKEIPTKKEASKCQDSSALLHPGLHYGVSQTTTIFM 897
Query: 1730 KYGAFLLRRSQAAASHRVLQRALECLPSKEHVDVIAKFAQLEFQLGDAERAKAIFENTLS 1789
+ FL++ HRVL L C + AQ + +A+ +
Sbjct: 898 ETIHFLMKVKAVQYVHRVLAHELLCPQGGPSCEYYLVLAQTHILKKNFAKAEEYLQQAAQ 957
Query: 1790 TYPKRTDVWSVYIDMTIKHGSQKDVRDIFERVIHLSLAPKRMKFFFKR----YL---DYE 1842
+VW + + G+ + + +ER I + M F F R YL +YE
Sbjct: 958 MDYLNPNVWGLKGHLYFLSGNHSEAKACYERTISFVVDASEMHFIFLRLGLIYLEEKEYE 1017
Query: 1843 KQHGT 1847
K T
Sbjct: 1018 KAKKT 1022
>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
sapiens]
Length = 722
Score = 49.7 bits (117), Expect = 3e-05
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 9/151 (5%)
Query: 1408 ASLEGQLTKQEERK---TEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEK-QQPQKP 1463
A L+ QL E+ ++ ++ K ++K++K +K+ K +EEVE K K ++P
Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571
Query: 1464 QAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQT 1523
+ +K S E + KP SEE+D + Y E ++ + + N LP EK
Sbjct: 572 KTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLG 631
Query: 1524 K-----PAEAPRLQLSSGFAWNVGLDSLTPA 1549
+ + P L+ S+ + ++L P+
Sbjct: 632 RVVHIIQSREPSLKNSNPDEIEIDFETLKPS 662
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 49.7 bits (117), Expect = 3e-05
Identities = 38/151 (25%), Positives = 70/151 (46%), Gaps = 9/151 (5%)
Query: 1408 ASLEGQLTKQEERK---TEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEK-QQPQKP 1463
A L+ QL E+ ++ ++ K ++K++K +K+ K +EEVE K K ++P
Sbjct: 512 AELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPK 571
Query: 1464 QAQKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQT 1523
+ +K S E + KP SEE+D + Y E ++ + + N LP EK
Sbjct: 572 KTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLG 631
Query: 1524 K-----PAEAPRLQLSSGFAWNVGLDSLTPA 1549
+ + P L+ S+ + ++L P+
Sbjct: 632 RVVHIIQSREPSLKNSNPDEIEIDFETLKPS 662
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 49.3 bits (116), Expect = 4e-05
Identities = 65/320 (20%), Positives = 135/320 (42%), Gaps = 44/320 (13%)
Query: 1406 LSASLEGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQA 1465
L+ E ++ +QEE+ E EE+ Q+ E+K +++ EK ++ + E K ++Q +
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 1466 QKRGGRECRESGSEQERVSKKPKKAGLSEEDDSLVDVYYREGKEEAEETNVLPKEKQTKP 1525
++ RE E EQE++ ++ +K +E++ + + +E ++E E +EK +
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEK---RQEEEKIRE---QEKRQEQEAKMWRQEEKIREQ 395
Query: 1526 AEAPRLQLSSGFAWNVGLDSLTPALPPLAESSDSEEDEKPHQATIKKSKKERELEKQKAE 1585
E R Q E E++EK + K ++E E+++Q E
Sbjct: 396 EEKIREQ----------------------EEMMQEQEEKMGEQEEKMWEQEEEMQEQ--E 431
Query: 1586 KELSRIEEALMDPGRQPESADDFDRLVLSSPNSSILWLQYMAFHLQATEIEKARAVAERA 1645
+++ R EE + + ++ ++ R +Q + E + A+
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIR-------EQEEMMQEQEEKMGEQEGKMCEQEAKMQ 484
Query: 1646 LKTISFREEQEKLNVWVALLNLENMYGSQESLTKVFERAVQYNEPLKVFLHLADIYAKSE 1705
+ R ++EK+ E QE + E +Q E K++ + + E
Sbjct: 485 EQEEKMRRQEEKIR------EQEKKIREQEEKIREQEEMMQEQEE-KMWEQEEKMCEQEE 537
Query: 1706 KFQEAGELYNRMLKRFRQEK 1725
K QE E R ++ R+++
Sbjct: 538 KMQEQEEKMRRQEEKMREQE 557
Score = 33.5 bits (75), Expect = 2.0
Identities = 19/71 (26%), Positives = 40/71 (56%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QE++ E EE+ ++ E+ Q++ EK ++ ++ E K ++Q +K + Q+
Sbjct: 494 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM 553
Query: 1471 RECRESGSEQE 1481
RE +QE
Sbjct: 554 REQEVRLRQQE 564
Score = 33.5 bits (75), Expect = 2.0
Identities = 20/69 (28%), Positives = 38/69 (55%)
Query: 1411 EGQLTKQEERKTEAEERDQKGEKKNQKRNEKKNQKGQEEVEMPSKEKQQPQKPQAQKRGG 1470
E ++ +QEE+ E EE Q+ E+K ++ EK ++ ++ E K ++Q +K + Q+
Sbjct: 501 EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRL 560
Query: 1471 RECRESGSE 1479
R+ E E
Sbjct: 561 RQQEEKMQE 569
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,153,261
Number of Sequences: 37866
Number of extensions: 3207128
Number of successful extensions: 24617
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 228
Number of HSP's successfully gapped in prelim test: 730
Number of HSP's that attempted gapping in prelim test: 14487
Number of HSP's gapped (non-prelim): 6000
length of query: 1871
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1754
effective length of database: 13,817,196
effective search space: 24235361784
effective search space used: 24235361784
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.