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Search of human proteins with 70980547
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70980547 FYVE-finger-containing Rab5 effector protein
rabenosyn-5 [Homo sapiens]
(784 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70980547 FYVE-finger-containing Rab5 effector protein rabenos... 1567 0.0
gi|191252785 centrobin, centrosomal BRCA2 interacting protein is... 78 3e-14
gi|80861396 centrobin, centrosomal BRCA2 interacting protein iso... 78 3e-14
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 3e-09
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 58 4e-08
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 58 4e-08
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 57 5e-08
gi|171906567 peripheral benzodiazepine receptor-associated prote... 57 7e-08
gi|171906559 peripheral benzodiazepine receptor-associated prote... 57 7e-08
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 56 1e-07
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 56 1e-07
gi|148746195 trichohyalin [Homo sapiens] 55 3e-07
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre... 54 4e-07
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 54 6e-07
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 52 2e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 52 2e-06
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 52 3e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 52 3e-06
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 52 3e-06
gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Ho... 51 4e-06
gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Ho... 51 4e-06
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 51 4e-06
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 51 5e-06
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 51 5e-06
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 51 5e-06
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 51 5e-06
gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens] 51 5e-06
gi|21493031 A-kinase anchor protein 13 isoform 3 [Homo sapiens] 51 5e-06
gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens] 51 5e-06
gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Hom... 50 6e-06
>gi|70980547 FYVE-finger-containing Rab5 effector protein
rabenosyn-5 [Homo sapiens]
Length = 784
Score = 1567 bits (4058), Expect = 0.0
Identities = 784/784 (100%), Positives = 784/784 (100%)
Query: 1 MASLDDPGEVREGFLCPLCLKDLQSFYQLHSHYEEEHSGEDRDVKGQIKSLVQKAKKAKD 60
MASLDDPGEVREGFLCPLCLKDLQSFYQLHSHYEEEHSGEDRDVKGQIKSLVQKAKKAKD
Sbjct: 1 MASLDDPGEVREGFLCPLCLKDLQSFYQLHSHYEEEHSGEDRDVKGQIKSLVQKAKKAKD 60
Query: 61 RLLKREGDDRAESGTQGYESFSYGGVDPYMWEPQELGAVRSHLSDFKKHRAARIDHYVVE 120
RLLKREGDDRAESGTQGYESFSYGGVDPYMWEPQELGAVRSHLSDFKKHRAARIDHYVVE
Sbjct: 61 RLLKREGDDRAESGTQGYESFSYGGVDPYMWEPQELGAVRSHLSDFKKHRAARIDHYVVE 120
Query: 121 VNKLIIRLEKLTAFDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCR 180
VNKLIIRLEKLTAFDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCR
Sbjct: 121 VNKLIIRLEKLTAFDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNKFSIRNRRHHCR 180
Query: 181 LCGSIMCKKCMELISLPLANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSV 240
LCGSIMCKKCMELISLPLANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSV
Sbjct: 181 LCGSIMCKKCMELISLPLANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSV 240
Query: 241 LDEKDDDRIRCCTHCKDTLLKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMA 300
LDEKDDDRIRCCTHCKDTLLKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMA
Sbjct: 241 LDEKDDDRIRCCTHCKDTLLKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMA 300
Query: 301 ASLNAGETTYSLEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRY 360
ASLNAGETTYSLEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRY
Sbjct: 301 ASLNAGETTYSLEHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRY 360
Query: 361 SATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLAS 420
SATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLAS
Sbjct: 361 SATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLAS 420
Query: 421 RAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMD 480
RAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMD
Sbjct: 421 RAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMD 480
Query: 481 EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVA 540
EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVA
Sbjct: 481 EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVA 540
Query: 541 SLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPSLSSTQPTRVW 600
SLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPSLSSTQPTRVW
Sbjct: 541 SLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPSLSSTQPTRVW 600
Query: 601 SGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPAAGVSLDPSARILKE 660
SGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPAAGVSLDPSARILKE
Sbjct: 601 SGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPAAGVSLDPSARILKE 660
Query: 661 YNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQRLSSPLVPGNPFEEPTCINPF 720
YNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQRLSSPLVPGNPFEEPTCINPF
Sbjct: 661 YNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQRLSSPLVPGNPFEEPTCINPF 720
Query: 721 EMDSDSGPEAEEPIEEELLLQQIDNIKAYIFDAKQCGRLDEVEVLTENLRELKHTLAKQK 780
EMDSDSGPEAEEPIEEELLLQQIDNIKAYIFDAKQCGRLDEVEVLTENLRELKHTLAKQK
Sbjct: 721 EMDSDSGPEAEEPIEEELLLQQIDNIKAYIFDAKQCGRLDEVEVLTENLRELKHTLAKQK 780
Query: 781 GGTD 784
GGTD
Sbjct: 781 GGTD 784
>gi|191252785 centrobin, centrosomal BRCA2 interacting protein
isoform alpha [Homo sapiens]
Length = 903
Score = 78.2 bits (191), Expect = 3e-14
Identities = 89/343 (25%), Positives = 146/343 (42%), Gaps = 45/343 (13%)
Query: 379 KEQFEELKKKRKEEMERKRAV---ERQAALESQRRLEERQSGLASRAANGEVASLRRGPA 435
KE ++ L+++ + ++ER++ E QAA E+Q +L QS + R GE+ + RR
Sbjct: 370 KEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEV--RRLEGELDTARRERD 427
Query: 436 PLRKAEGWLPLSGGQGQSE------DSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENL 489
L+ L +S Q + E +S+ +Q +T + QA+ + + +
Sbjct: 428 ALQ-----LEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHR 482
Query: 490 RQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSL 549
+QLQD Q Q E A +L++ + E + + Q Q+ + EL REQ RV L + + L
Sbjct: 483 KQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQL 542
Query: 550 DFREIGPFQ-LEPSREPRTHLAYALDLGSSPVPSSTAPKT------PSLSSTQPTRVWSG 602
+ + + + L+ + A L + P P+ AP P + RVW+
Sbjct: 543 EEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVWTM 602
Query: 603 PP-AVGQERLPQSSMPQQHEGPSLNPF---DEEDLSSPMEEATTGPPAAGVSLDPSARIL 658
PP AV + + Q S + E P P DLS + L PS +
Sbjct: 603 PPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLS--------------LLLGPSFQSQ 648
Query: 659 KEYNPFEEEDEEEEAVAGN----PFIQPDSPAPNPFSEEDEHP 697
+ P E + + + AG PD A PF EED P
Sbjct: 649 HSFQPLEPKPDLTSSTAGAFSALGAFHPDHRAERPFPEEDPGP 691
>gi|80861396 centrobin, centrosomal BRCA2 interacting protein
isoform beta [Homo sapiens]
Length = 925
Score = 78.2 bits (191), Expect = 3e-14
Identities = 89/343 (25%), Positives = 146/343 (42%), Gaps = 45/343 (13%)
Query: 379 KEQFEELKKKRKEEMERKRAV---ERQAALESQRRLEERQSGLASRAANGEVASLRRGPA 435
KE ++ L+++ + ++ER++ E QAA E+Q +L QS + R GE+ + RR
Sbjct: 370 KEHYQALQEESQAQLEREKEKSQREAQAAWETQHQLALVQSEV--RRLEGELDTARRERD 427
Query: 436 PLRKAEGWLPLSGGQGQSE------DSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENL 489
L+ L +S Q + E +S+ +Q +T + QA+ + + +
Sbjct: 428 ALQ-----LEMSLVQARYESQRIQLESELAVQLEQRVTERLAQAQESSLRQAASLREHHR 482
Query: 490 RQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSL 549
+QLQD Q Q E A +L++ + E + + Q Q+ + EL REQ RV L + + L
Sbjct: 483 KQLQDLSGQHQQELASQLAQFKVEMAEREERQQQVAEDYELRLAREQARVCELQSGNQQL 542
Query: 550 DFREIGPFQ-LEPSREPRTHLAYALDLGSSPVPSSTAPKT------PSLSSTQPTRVWSG 602
+ + + + L+ + A L + P P+ AP P + RVW+
Sbjct: 543 EEQRVELVERLQAMLQAHWDEANQLLSTTLPPPNPPAPPAGPSSPGPQEPEKEERRVWTM 602
Query: 603 PP-AVGQERLPQSSMPQQHEGPSLNPF---DEEDLSSPMEEATTGPPAAGVSLDPSARIL 658
PP AV + + Q S + E P P DLS + L PS +
Sbjct: 603 PPMAVALKPVLQQSREARDELPGAPPVLCSSSSDLS--------------LLLGPSFQSQ 648
Query: 659 KEYNPFEEEDEEEEAVAGN----PFIQPDSPAPNPFSEEDEHP 697
+ P E + + + AG PD A PF EED P
Sbjct: 649 HSFQPLEPKPDLTSSTAGAFSALGAFHPDHRAERPFPEEDPGP 691
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 61.6 bits (148), Expect = 3e-09
Identities = 83/394 (21%), Positives = 147/394 (37%), Gaps = 69/394 (17%)
Query: 386 KKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLP 445
+KKR++E E K ++R L++ + ++ L + +P R+ +
Sbjct: 19 EKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM-- 73
Query: 446 LSGGQGQSEDSDPLL----------QQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDE 495
+ + E+ D L +++H+ R+ K R+ E E ++ ++E
Sbjct: 74 ----EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE 129
Query: 496 YDQQQTE----KAIELSRRQAEEEDLQREQLQMLRERELE-------------------- 531
D+ + E K E++R + E + EQL+ RERE +
Sbjct: 130 QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEE 189
Query: 532 --REREQFRVASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGSSPVPSSTAP 586
+ERE R S H RT D+ + + P R PR + L G PV
Sbjct: 190 RRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGRKPVKEEKME 247
Query: 587 KTPSLSS----------TQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSP 636
+ LS T S G E + ++ EG + +EE+
Sbjct: 248 ERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEE 307
Query: 637 MEEATTGPPAAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEH 696
EE TG + S + SA + E E+E+ E E + + P+S E +E
Sbjct: 308 EEEEETGSNSEEAS-EQSAEEVSEEEMSEDEERENE---NHLLVVPESRFDRDSGESEEA 363
Query: 697 PQQ-----RLSSPLVPGNPFEEPTCINPFEMDSD 725
++ SS L G+ + ++P E+ +
Sbjct: 364 EEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 397
Score = 37.4 bits (85), Expect = 0.054
Identities = 61/299 (20%), Positives = 126/299 (42%), Gaps = 25/299 (8%)
Query: 260 LKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHASDLR 319
+KR + D+++ D ++ E CME + +P Y R + + GE SL +
Sbjct: 32 IKRLKNSDDRDSKRDSLEEGELRDHCMEITIRNSP-YRREDSMEDRGEEDDSLAIKPPQQ 90
Query: 320 VE-VQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLM---S 375
+ +KV+ D K+ + + H R + + + ++K + S
Sbjct: 91 MSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS 150
Query: 376 LPTKEQFEELKKKRKEEME-RKRAVERQAALESQRRLEERQSGL-ASRAANGEVASLRRG 433
+++ E+L++KR+ E + R++ E++ E +RR EER+ A R + ++R
Sbjct: 151 RRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMRED 210
Query: 434 PAPLRKAEGW-----------LPLSGG-----QGQSEDSDPLLQQIHNITSFIRQAKAAG 477
+ KA W L G + + E+ D LL + +I+ R+ +A
Sbjct: 211 YSDKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA- 268
Query: 478 RMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
+ + + ++E ++++ E S + EEE+ + E+ E E+ E+
Sbjct: 269 ESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 327
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 57.8 bits (138), Expect = 4e-08
Identities = 58/265 (21%), Positives = 105/265 (39%), Gaps = 31/265 (11%)
Query: 486 QENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELER-------EREQFR 538
++ R++ E+ +++ ++ +L R++ E ++ +Q + ++E ER ERE R
Sbjct: 116 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 175
Query: 539 VASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPSLSS-- 593
S H RT D+ + + P R PR + L G PV + LS
Sbjct: 176 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGRKPVKEEKMEERDLLSDLQ 233
Query: 594 --------TQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPP 645
T S G E + ++ EG + +EE+ EE TG
Sbjct: 234 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 293
Query: 646 AAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQ-----R 700
+ S + SA + E E+E+ E E + + P+S E +E ++
Sbjct: 294 SEEAS-EQSAEEVSEEEMSEDEERENE---NHLLVVPESRFDRDSGESEEAEEEVGEGTP 349
Query: 701 LSSPLVPGNPFEEPTCINPFEMDSD 725
SS L G+ + ++P E+ +
Sbjct: 350 QSSALTEGDYVPDSPALSPIELKQE 374
Score = 36.6 bits (83), Expect = 0.092
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 20/176 (11%)
Query: 379 KEQFEELKKKRKEEME-RKRAVERQAALESQRRLEERQSGL-ASRAANGEVASLRRGPAP 436
+++ E+L++KR+ E + R++ E++ E +RR EER+ A R + ++R +
Sbjct: 131 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 190
Query: 437 LRKAEGW-----------LPLSGG-----QGQSEDSDPLLQQIHNITSFIRQAKAAGRMD 480
KA W L G + + E+ D LL + +I+ R+ +A
Sbjct: 191 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA-ESS 248
Query: 481 EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
+ + + ++E ++++ E S + EEE+ + E+ E E+ E+
Sbjct: 249 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 304
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 57.8 bits (138), Expect = 4e-08
Identities = 58/265 (21%), Positives = 105/265 (39%), Gaps = 31/265 (11%)
Query: 486 QENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELER-------EREQFR 538
++ R++ E+ +++ ++ +L R++ E ++ +Q + ++E ER ERE R
Sbjct: 150 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 209
Query: 539 VASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPSLSS-- 593
S H RT D+ + + P R PR + L G PV + LS
Sbjct: 210 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGRKPVKEEKMEERDLLSDLQ 267
Query: 594 --------TQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPP 645
T S G E + ++ EG + +EE+ EE TG
Sbjct: 268 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 327
Query: 646 AAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQ-----R 700
+ S + SA + E E+E+ E E + + P+S E +E ++
Sbjct: 328 SEEAS-EQSAEEVSEEEMSEDEERENE---NHLLVVPESRFDRDSGESEEAEEEVGEGTP 383
Query: 701 LSSPLVPGNPFEEPTCINPFEMDSD 725
SS L G+ + ++P E+ +
Sbjct: 384 QSSALTEGDYVPDSPALSPIELKQE 408
Score = 36.6 bits (83), Expect = 0.092
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 20/176 (11%)
Query: 379 KEQFEELKKKRKEEME-RKRAVERQAALESQRRLEERQSGL-ASRAANGEVASLRRGPAP 436
+++ E+L++KR+ E + R++ E++ E +RR EER+ A R + ++R +
Sbjct: 165 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 224
Query: 437 LRKAEGW-----------LPLSGG-----QGQSEDSDPLLQQIHNITSFIRQAKAAGRMD 480
KA W L G + + E+ D LL + +I+ R+ +A
Sbjct: 225 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA-ESS 282
Query: 481 EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
+ + + ++E ++++ E S + EEE+ + E+ E E+ E+
Sbjct: 283 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 338
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 57.4 bits (137), Expect = 5e-08
Identities = 84/403 (20%), Positives = 151/403 (37%), Gaps = 78/403 (19%)
Query: 386 KKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLP 445
+KKR++E E K ++R L++ + ++ L + +P R+ +
Sbjct: 19 EKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM-- 73
Query: 446 LSGGQGQSEDSDPLL----------QQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDE 495
+ + E+ D L +++H+ R+ K R+ E E ++ ++E
Sbjct: 74 ----EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREE 129
Query: 496 YD--------QQQTEKAIELSRRQA------------EEEDLQREQLQMLRERELE---- 531
D Q++ E A E SRR+ E+ + +RE+ + +RE++ E
Sbjct: 130 QDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQ 189
Query: 532 -----------REREQFRVASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGS 577
+ERE R S H RT D+ + + P R PR + L G
Sbjct: 190 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGR 247
Query: 578 SPVPSSTAPKTPSLS----------STQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNP 627
PV + LS T S G E + ++ EG +
Sbjct: 248 KPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEE 307
Query: 628 FDEEDLSSPMEEATTGPPAAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAP 687
+EE+ EE TG + S + SA + E E+E+ E E + + P+S
Sbjct: 308 SEEEEEEEEEEEEETGSNSEEAS-EQSAEEVSEEEMSEDEERENE---NHLLVVPESRFD 363
Query: 688 NPFSEEDEHPQQ-----RLSSPLVPGNPFEEPTCINPFEMDSD 725
E +E ++ SS L G+ + ++P E+ +
Sbjct: 364 RDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 406
Score = 36.6 bits (83), Expect = 0.092
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 20/176 (11%)
Query: 379 KEQFEELKKKRKEEME-RKRAVERQAALESQRRLEERQSGL-ASRAANGEVASLRRGPAP 436
+++ E+L++KR+ E + R++ E++ E +RR EER+ A R + ++R +
Sbjct: 163 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 222
Query: 437 LRKAEGW-----------LPLSGG-----QGQSEDSDPLLQQIHNITSFIRQAKAAGRMD 480
KA W L G + + E+ D LL + +I+ R+ +A
Sbjct: 223 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA-ESS 280
Query: 481 EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
+ + + ++E ++++ E S + EEE+ + E+ E E+ E+
Sbjct: 281 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
>gi|171906567 peripheral benzodiazepine receptor-associated protein
1 isoform b [Homo sapiens]
Length = 1797
Score = 57.0 bits (136), Expect = 7e-08
Identities = 102/363 (28%), Positives = 142/363 (39%), Gaps = 75/363 (20%)
Query: 373 LMSLPTKEQF-----EELKKKRK--EEMERKRAVERQAALESQRRLEERQSGLASRAANG 425
++ P KEQ EL KKRK E +E Q A + QRR EE + L R A
Sbjct: 267 ILGEPEKEQRVQQLESELSKKRKKCESLE-------QEARKKQRRCEELE--LQLRQAQN 317
Query: 426 EVASL------RRGPAPLRKAEGW--LPLSGG-QGQSEDSDPLLQQIHNITSFIRQAKAA 476
E A L G A ++ W L G G +++ D L++ + S + +
Sbjct: 318 ENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQV 377
Query: 477 GRMDEVRTLQENLRQLQDEYDQQQ---TEKAIELSRRQAEEEDLQREQLQMLRERELERE 533
+ +R + + +QL+ E++Q + EK E+ R Q + + QRE ++ E +
Sbjct: 378 --LKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLD 435
Query: 534 REQFRVASLHTRTR------SLDFREIGPFQLEPSREPRTHLAYALD---LGSSPVP--- 581
Q RV L + R SL +E+ F+L P P L ALD LG P P
Sbjct: 436 SMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPG--PLDLLTSALDCGSLGDCPPPPCC 493
Query: 582 -------SSTAPK------------TPSLSSTQPTRVWSGP--PAVGQERLPQSSMPQQ- 619
+ PK TP S P + P A E L SS +
Sbjct: 494 CSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKKAESLSNSSHSESI 553
Query: 620 HEGPSLNPFDEEDLSSPMEEATTGP----PAAGVSLDPSARI-----LKEYNPFEEEDEE 670
H P P E D +S +EE PAA ARI YNPFE +E
Sbjct: 554 HNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLARYSYNPFEGPNEN 613
Query: 671 EEA 673
EA
Sbjct: 614 PEA 616
>gi|171906559 peripheral benzodiazepine receptor-associated protein
1 isoform a [Homo sapiens]
Length = 1857
Score = 57.0 bits (136), Expect = 7e-08
Identities = 102/363 (28%), Positives = 142/363 (39%), Gaps = 75/363 (20%)
Query: 373 LMSLPTKEQF-----EELKKKRK--EEMERKRAVERQAALESQRRLEERQSGLASRAANG 425
++ P KEQ EL KKRK E +E Q A + QRR EE + L R A
Sbjct: 327 ILGEPEKEQRVQQLESELSKKRKKCESLE-------QEARKKQRRCEELE--LQLRQAQN 377
Query: 426 EVASL------RRGPAPLRKAEGW--LPLSGG-QGQSEDSDPLLQQIHNITSFIRQAKAA 476
E A L G A ++ W L G G +++ D L++ + S + +
Sbjct: 378 ENARLVEENSRLSGRATEKEQVEWENAELRGQLLGVTQERDSALRKSQGLQSKLESLEQV 437
Query: 477 GRMDEVRTLQENLRQLQDEYDQQQ---TEKAIELSRRQAEEEDLQREQLQMLRERELERE 533
+ +R + + +QL+ E++Q + EK E+ R Q + + QRE ++ E +
Sbjct: 438 --LKHMREVAQRRQQLEVEHEQARLSLREKQEEVRRLQQAQAEAQREHEGAVQLLESTLD 495
Query: 534 REQFRVASLHTRTR------SLDFREIGPFQLEPSREPRTHLAYALD---LGSSPVP--- 581
Q RV L + R SL +E+ F+L P P L ALD LG P P
Sbjct: 496 SMQARVRELEEQCRSQTEQFSLLAQELQAFRLHPG--PLDLLTSALDCGSLGDCPPPPCC 553
Query: 582 -------SSTAPK------------TPSLSSTQPTRVWSGP--PAVGQERLPQSSMPQQ- 619
+ PK TP S P + P A E L SS +
Sbjct: 554 CSIPQPCRGSGPKDLDLPPGSPGRCTPKSSEPAPATLTGVPRRTAKKAESLSNSSHSESI 613
Query: 620 HEGPSLNPFDEEDLSSPMEEATTGP----PAAGVSLDPSARI-----LKEYNPFEEEDEE 670
H P P E D +S +EE PAA ARI YNPFE +E
Sbjct: 614 HNSPKSCPTPEVDTASEVEELEADSVSLLPAAPEGSRGGARIQVFLARYSYNPFEGPNEN 673
Query: 671 EEA 673
EA
Sbjct: 674 PEA 676
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/265 (21%), Positives = 104/265 (39%), Gaps = 31/265 (11%)
Query: 486 QENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELER-------EREQFR 538
++ R++ E+ +++ ++ +L R++ E ++ +Q + ++E ER ERE R
Sbjct: 138 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 197
Query: 539 VASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPSLSS-- 593
S H RT D+ + + P R PR + L G PV + LS
Sbjct: 198 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGRKPVKEEKMEERDLLSDLQ 255
Query: 594 --------TQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPP 645
T S G E + ++ EG + +EE+ EE TG
Sbjct: 256 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 315
Query: 646 AAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQ-----R 700
+ S + SA + E E+E+ E E + + P+S E +E ++
Sbjct: 316 SEEAS-EQSAEEVSEEEMSEDEERENE---NHLLVVPESRFDRDSGESEEAEEEVGEGTP 371
Query: 701 LSSPLVPGNPFEEPTCINPFEMDSD 725
SS L G+ + + P E+ +
Sbjct: 372 QSSALTEGDYVPDSPALLPIELKQE 396
Score = 55.1 bits (131), Expect = 3e-07
Identities = 90/395 (22%), Positives = 142/395 (35%), Gaps = 89/395 (22%)
Query: 386 KKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLP 445
+KKR++E E K ++R L++ + ++ L + +P R+ +
Sbjct: 19 EKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM-- 73
Query: 446 LSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQ-----------ENLRQLQD 494
+ + E+ D L I R+ K R DE R + E ++ ++
Sbjct: 74 ----EDRGEEDDSLA--IKPPQQMSRKEKVHHRKDEKRKEKWKHARVKEREHERRKRHRE 127
Query: 495 EYDQQQTE----KAIELSRRQAEEEDLQREQLQMLRERELE------------------- 531
E D+ + E K E++R + E + EQL+ RERE +
Sbjct: 128 EQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAE 187
Query: 532 ---REREQFRVASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGSSPVPSSTA 585
+ERE R S H RT D+ + + P R PR + L G PV
Sbjct: 188 ERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGRKPVKEEKM 245
Query: 586 PKTPSLSSTQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPP 645
+ LS Q ER S+ E S + +EE+ EE +T
Sbjct: 246 EERDLLSDLQDIS--------DSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTS-- 295
Query: 646 AAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSE----EDEHPQQRL 701
+E EEE+EEEE G+ + + SE EDE +
Sbjct: 296 -------------EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENEN 342
Query: 702 SSPLVPGNPFEEPTCINPFEMDSDSGPEAEEPIEE 736
+VP + F+ DS EAEE + E
Sbjct: 343 HLLVVPESRFDR---------DSGESEEAEEEVGE 368
Score = 36.6 bits (83), Expect = 0.092
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 20/176 (11%)
Query: 379 KEQFEELKKKRKEEME-RKRAVERQAALESQRRLEERQSGL-ASRAANGEVASLRRGPAP 436
+++ E+L++KR+ E + R++ E++ E +RR EER+ A R + ++R +
Sbjct: 153 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 212
Query: 437 LRKAEGW-----------LPLSGG-----QGQSEDSDPLLQQIHNITSFIRQAKAAGRMD 480
KA W L G + + E+ D LL + +I+ R+ +A
Sbjct: 213 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA-ESS 270
Query: 481 EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
+ + + ++E ++++ E S + EEE+ + E+ E E+ E+
Sbjct: 271 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 326
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 56.2 bits (134), Expect = 1e-07
Identities = 58/265 (21%), Positives = 104/265 (39%), Gaps = 31/265 (11%)
Query: 486 QENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELER-------EREQFR 538
++ R++ E+ +++ ++ +L R++ E ++ +Q + ++E ER ERE R
Sbjct: 148 RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARR 207
Query: 539 VASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGSSPVPSSTAPKTPSLSS-- 593
S H RT D+ + + P R PR + L G PV + LS
Sbjct: 208 EVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGRKPVKEEKMEERDLLSDLQ 265
Query: 594 --------TQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPP 645
T S G E + ++ EG + +EE+ EE TG
Sbjct: 266 DISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSN 325
Query: 646 AAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQ-----R 700
+ S + SA + E E+E+ E E + + P+S E +E ++
Sbjct: 326 SEEAS-EQSAEEVSEEEMSEDEERENE---NHLLVVPESRFDRDSGESEEAEEEVGEGTP 381
Query: 701 LSSPLVPGNPFEEPTCINPFEMDSD 725
SS L G+ + + P E+ +
Sbjct: 382 QSSALTEGDYVPDSPALLPIELKQE 406
Score = 51.6 bits (122), Expect = 3e-06
Identities = 88/403 (21%), Positives = 146/403 (36%), Gaps = 95/403 (23%)
Query: 386 KKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLP 445
+KKR++E E K ++R L++ + ++ L + +P R+ +
Sbjct: 19 EKKRRKEQEEKAEIKR---LKNSDDRDSKRDSLEEGELRDHCMEITIRNSPYRREDSM-- 73
Query: 446 LSGGQGQSEDSDPLL----------QQIHNITSFIRQAKA--------AGRMDEVRTLQ- 486
+ + E+ D L +++H+ R+ K G+ V+ +
Sbjct: 74 ----EDRGEEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKHARVKEREH 129
Query: 487 ENLRQLQDEYDQQQTE----KAIELSRRQAEEEDLQREQLQMLRERELE----------- 531
E ++ ++E D+ + E K E++R + E + EQL+ RERE +
Sbjct: 130 ERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQ 189
Query: 532 -----------REREQFRVASLHTRTRSLDFRE---IGPFQLEPSREPRTHLAYALDLGS 577
+ERE R S H RT D+ + + P R PR + L G
Sbjct: 190 KERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER--FELGDGR 247
Query: 578 SPVPSSTAPKTPSLSSTQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPM 637
PV + LS Q ER S+ E S + +EE+
Sbjct: 248 KPVKEEKMEERDLLSDLQDIS--------DSERKTSSAESSSAESGSGSEEEEEEEEEEE 299
Query: 638 EEATTGPPAAGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSE----E 693
EE +T +E EEE+EEEE G+ + + SE E
Sbjct: 300 EEGSTS---------------EESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSE 344
Query: 694 DEHPQQRLSSPLVPGNPFEEPTCINPFEMDSDSGPEAEEPIEE 736
DE + +VP + F+ DS EAEE + E
Sbjct: 345 DEERENENHLLVVPESRFDR---------DSGESEEAEEEVGE 378
Score = 36.6 bits (83), Expect = 0.092
Identities = 38/176 (21%), Positives = 79/176 (44%), Gaps = 20/176 (11%)
Query: 379 KEQFEELKKKRKEEME-RKRAVERQAALESQRRLEERQSGL-ASRAANGEVASLRRGPAP 436
+++ E+L++KR+ E + R++ E++ E +RR EER+ A R + ++R +
Sbjct: 163 RDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSD 222
Query: 437 LRKAEGW-----------LPLSGG-----QGQSEDSDPLLQQIHNITSFIRQAKAAGRMD 480
KA W L G + + E+ D LL + +I+ R+ +A
Sbjct: 223 KVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERD-LLSDLQDISDSERKTSSA-ESS 280
Query: 481 EVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
+ + + ++E ++++ E S + EEE+ + E+ E E+ E+
Sbjct: 281 SAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEE 336
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 54.7 bits (130), Expect = 3e-07
Identities = 52/193 (26%), Positives = 88/193 (45%), Gaps = 25/193 (12%)
Query: 383 EELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEG 442
EEL+++ ++ + +R R+ LE Q R EE E LR P R+ E
Sbjct: 1054 EELQQEEEQLLGEERETRRRQELERQYRKEEELQ-------QEEEQLLREEPEKRRRQER 1106
Query: 443 WLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQQQTE 502
+ Q + + L Q+ + R+ + ++ +E ++Q +++ +++ E
Sbjct: 1107 -------ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 503 KAI--ELSRRQAEEEDLQREQLQMLRE----RELERER-----EQFRVASLHTRTRSLDF 551
K EL R+ EEE+LQ+E+ Q+LRE R ERER E+ + R R D
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
Query: 552 REIGPFQLEPSRE 564
R +Q EP +E
Sbjct: 1220 RSDLKWQWEPEKE 1232
Score = 52.4 bits (124), Expect = 2e-06
Identities = 48/175 (27%), Positives = 80/175 (45%), Gaps = 36/175 (20%)
Query: 383 EELKKKRKEEMER-----KRAVERQAAL-----ESQRRLEERQSGLASRAANGEVASLRR 432
EE +K+R++E ER K+ +++ L E +RR E + E L R
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005
Query: 433 GPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQL 492
R+ + W + Q D L Q+ + +R+ + E R LQE RQ
Sbjct: 1006 EEREKRRRQEW------ERQYRKKDELQQEEEQL---LREER------EKRRLQERERQY 1050
Query: 493 QDEYDQQQTEKAI-----------ELSRRQAEEEDLQREQLQMLRERELEREREQ 536
++E + QQ E+ + EL R+ +EE+LQ+E+ Q+LRE +R R++
Sbjct: 1051 REEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105
Score = 50.1 bits (118), Expect = 8e-06
Identities = 44/173 (25%), Positives = 80/173 (46%), Gaps = 10/173 (5%)
Query: 367 QEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLE-ERQSGLASRAANG 425
+E+LLG + Q E K + +EE++++ + E +RR E ERQ
Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029
Query: 426 EVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTL 485
E LR R L + Q + + L Q+ + R+ + ++
Sbjct: 1030 EEQLLREEREKRR-------LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082
Query: 486 QENLRQLQDEYDQQQTEK--AIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
+E L+Q +++ +++ EK E R+ EEE+LQ+E+ Q+LRE +R R++
Sbjct: 1083 EEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/177 (26%), Positives = 78/177 (44%), Gaps = 14/177 (7%)
Query: 379 KEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLR 438
+E+ E+L+K ++E+ R+R E Q + QR E+Q E RR R
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQ---QQQRLRREQQLRRKQEEERREQQEERREQQERR 328
Query: 439 KAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQ 498
+ + Q + E + QQ+ R+ + R E ++ LR+ Q +
Sbjct: 329 EQQE--ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRRE 386
Query: 499 QQTEKAIELSRRQA--------EEEDLQREQLQMLRERELEREREQFRVASLHTRTR 547
QQ + +L R Q E+ L+REQ Q+ RE++L RE+E+ R H + R
Sbjct: 387 QQLRREQQLRREQQLRREQQLRREQQLRREQ-QLRREQQLRREQEEERHEQKHEQER 442
Score = 48.5 bits (114), Expect = 2e-05
Identities = 42/164 (25%), Positives = 79/164 (48%), Gaps = 22/164 (13%)
Query: 376 LPTKEQFEELKKKRKEEMERKRAVERQAALESQRR---LEERQSGLASRAANGEVASLRR 432
LP +E+ E+ +++R+E + + +E + L+ + R L+E + GL + RR
Sbjct: 811 LPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGL-------QEDQERR 863
Query: 433 GPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQL 492
R+ + W + Q E+ ++ T + + A E + LQE +L
Sbjct: 864 RSQEQRRDQKW------RWQLEEE----RKRRRHTLYAKPALQEQLRKEQQLLQEEEEEL 913
Query: 493 QDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQ 536
Q E +++ + E R+ EEE LQ+E+ Q+LRE +R R++
Sbjct: 914 QRE--EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE 955
Score = 47.4 bits (111), Expect = 5e-05
Identities = 51/187 (27%), Positives = 77/187 (41%), Gaps = 31/187 (16%)
Query: 379 KEQFEELKKKRKEEMERKRAVERQAALESQRR-LEERQSGLASRA----ANGEVASLRRG 433
+EQ + K EE + + R+ LE +R+ EE+Q R E R+
Sbjct: 190 EEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR 249
Query: 434 PAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEV----------- 482
LRK E L Q Q E L ++ + RQ R +E
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRE----LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Query: 483 ---------RTLQENLRQLQDEYDQQQTEKAIELSRRQAE--EEDLQREQLQMLRERELE 531
R QE R+ Q+ +QQ+ + +L R Q E E+ L+REQ + RE++L
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 532 REREQFR 538
RE+E+ R
Sbjct: 366 REQEEER 372
Score = 46.6 bits (109), Expect = 9e-05
Identities = 53/224 (23%), Positives = 99/224 (44%), Gaps = 14/224 (6%)
Query: 352 LRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRL 411
LR ++ +R L +++L L +EQ EE +++ E+ R++ ++R+ E +R
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQL-RREQEEERHEQKHEQERREQRLKREQ--EERRDW 457
Query: 412 EERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIR 471
+R+ L+R R+ E WL L + + E + QQ+ R
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERR-ERWLKLEEEE-RREQQERREQQLRREQEERR 515
Query: 472 QAKAAGRMDEVRTLQ-----ENLRQLQDEYDQQ----QTEKAIELSRRQAEEEDLQREQL 522
+ + + +E R Q + LR+ Q+E +Q + EK +E RR+ + Q E+
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERR 575
Query: 523 QMLRERELEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPR 566
L +RE ER +++ + + L E+ + E RE R
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Score = 42.4 bits (98), Expect = 0.002
Identities = 41/160 (25%), Positives = 73/160 (45%), Gaps = 15/160 (9%)
Query: 379 KEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLR 438
+E+ E +++R+E+ ER+ E + + +R EER+ R E RR R
Sbjct: 311 EEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE----RREQQLRR 366
Query: 439 KAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQ 498
+ E + + E QQ+ R+ + R ++ ++ LR+ Q +
Sbjct: 367 EQE--------EERREQQLRREQQLRREQQLRREQQL--RREQQLRREQQLRREQQLRRE 416
Query: 499 QQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFR 538
QQ + +L R Q EE Q+ + Q RE+ L+RE+E+ R
Sbjct: 417 QQLRREQQLRREQEEERHEQKHE-QERREQRLKREQEERR 455
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/159 (22%), Positives = 71/159 (44%), Gaps = 21/159 (13%)
Query: 381 QFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKA 440
Q EE +K+R+ + K A++ Q E Q EE + L+R R+
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEE-------------LQREEREKRRR 923
Query: 441 EGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQQQ 500
+ + Q + + L Q+ + R+ + + + L+Q +++ ++
Sbjct: 924 QEQ------ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977
Query: 501 TEKAI--ELSRRQAEEEDLQREQLQMLRERELEREREQF 537
EK E ++ EEE+LQ+E+ Q+LRE +R R+++
Sbjct: 978 PEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Score = 42.0 bits (97), Expect = 0.002
Identities = 40/165 (24%), Positives = 73/165 (44%), Gaps = 5/165 (3%)
Query: 377 PTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAP 436
P +EQ E ++K + +RK E+Q L +R + R+ + E R P
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQL-LREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 437 LRKAEGWLPLSGGQ-GQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDE 495
LR+ E + E L++ + R+ K ++R QE +QL+ +
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRC-QEREQQLRQD 1411
Query: 496 YDQQQTEKAIELSRRQAEEEDLQREQ--LQMLRERELEREREQFR 538
D++ E+ +LSR++ + + + EQ + RER+ E +Q R
Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLR 1456
Score = 40.8 bits (94), Expect = 0.005
Identities = 47/185 (25%), Positives = 83/185 (44%), Gaps = 22/185 (11%)
Query: 383 EELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEG 442
EEL ++R+E ER+ + L+S + E + + E+ LRR ++
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQ--- 227
Query: 443 WLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQE---NLRQLQDEYDQQ 499
Q + E D + Q+ R+ + R +E + +E R+LQ+E +Q
Sbjct: 228 -------QQRRERQDRVFQEEEE--KEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 500 QTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSLDFREIGPFQL 559
+ + EL R + EEE ++Q ++ RE++L R++E+ R R + RE Q
Sbjct: 279 RKLERQELRRERQEEE---QQQQRLRREQQLRRKQEEERREQQEERREQQERRE----QQ 331
Query: 560 EPSRE 564
E RE
Sbjct: 332 EERRE 336
Score = 40.8 bits (94), Expect = 0.005
Identities = 45/184 (24%), Positives = 82/184 (44%), Gaps = 27/184 (14%)
Query: 383 EELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEG 442
E+L+K+++ E + ++R+ + +R+ +ERQ + E LR R+ E
Sbjct: 897 EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE- 955
Query: 443 WLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQQQTE 502
+ + D LQQ ++ + G E R QE ++ ++E + QQ E
Sbjct: 956 -------RERQYRKDKKLQQ--------KEEQLLGEEPEKRRRQEREKKYREEEELQQEE 1000
Query: 503 KAI-----ELSRRQA-EEEDLQREQLQMLRERELEREREQFRVASLHTRTRSLDFREIGP 556
+ + E RRQ E + ++++LQ E+ L ERE+ R+ + R +RE
Sbjct: 1001 EQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL-----QERERQYREEEE 1055
Query: 557 FQLE 560
Q E
Sbjct: 1056 LQQE 1059
Score = 40.0 bits (92), Expect = 0.008
Identities = 47/191 (24%), Positives = 83/191 (43%), Gaps = 16/191 (8%)
Query: 353 RLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLE 412
R QR+ R +Q++L L + + EE +++ + E KR + + +R E
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQL--RREQEERREQLLKREEEKRLEQERREQRLKREQE 572
Query: 413 ERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQ 472
ER+ L R L+R + E L + E+ + L Q+ R+
Sbjct: 573 ERRDQLLKREEERRQQRLKREQE--ERLEQRL-------KREEVERLEQEERREQRLKRE 623
Query: 473 AKAAGRMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQ----REQLQMLRER 528
R ++ +E + Q + ++Q E+ + +R+ EEE L+ RE + RE+
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 529 EL-EREREQFR 538
EL E E+EQ R
Sbjct: 684 ELAEEEQEQAR 694
Score = 39.7 bits (91), Expect = 0.011
Identities = 49/197 (24%), Positives = 83/197 (42%), Gaps = 29/197 (14%)
Query: 379 KEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLR 438
+E+ E +++R++++ R++ R+ L+ Q E Q L S RR R
Sbjct: 493 EEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR 552
Query: 439 KAEGWLPLSGGQG-----QSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQ 493
+ E L + Q E D LL++ R+ + R E R L++ L++ +
Sbjct: 553 EEEKRLEQERREQRLKREQEERRDQLLKREEE-----RRQQRLKREQEER-LEQRLKREE 606
Query: 494 DEYDQQQTEKAIELSRRQAEEE-----------------DLQREQLQMLRERELEREREQ 536
E +Q+ + L R + EEE L+REQ Q RE+ L+RE E+
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ-QERREQRLKREEEE 665
Query: 537 FRVASLHTRTRSLDFRE 553
R+ R + RE
Sbjct: 666 ERLEQRLKREHEEERRE 682
Score = 39.3 bits (90), Expect = 0.014
Identities = 44/173 (25%), Positives = 74/173 (42%), Gaps = 11/173 (6%)
Query: 381 QFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKA 440
Q EE +K+R++E ER+ E Q E ++ L E + R R+ +K
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREERE---KRRRQERERQYRKDKKLQQKE 970
Query: 441 EGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQQQ 500
E L + + ++ + ++ + Q R E R QE RQ + + + QQ
Sbjct: 971 EQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER--EKRRRQEWERQYRKKDELQQ 1028
Query: 501 TEKAI---ELSRRQAEEEDLQ---REQLQMLRERELEREREQFRVASLHTRTR 547
E+ + E +R+ +E + Q E+LQ E+ L ERE R L + R
Sbjct: 1029 EEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081
Score = 38.1 bits (87), Expect = 0.032
Identities = 43/184 (23%), Positives = 77/184 (41%), Gaps = 8/184 (4%)
Query: 392 EMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQG 451
+ + + R E QRR +E++ R + + R ++ E +
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 452 QSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQ---QQTEKAIELS 508
E S+ Q++ Q + R +E + ++ ++E +Q Q+ E+ EL
Sbjct: 773 AEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQ 832
Query: 509 RRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPRTH 568
+ EE+ +RE+ Q L+E E + +Q R S R R +R +QLE R+ R H
Sbjct: 833 FLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR-RDQKWR----WQLEEERKRRRH 887
Query: 569 LAYA 572
YA
Sbjct: 888 TLYA 891
Score = 37.7 bits (86), Expect = 0.041
Identities = 64/305 (20%), Positives = 123/305 (40%), Gaps = 35/305 (11%)
Query: 256 KDTLLKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHA 315
++ L + E+Q+ +E P+ + E+ R C E+ + + E E E
Sbjct: 1083 EEELQQEEEQLLREE--PEKRRRQERERQCREEEELQQEE-----------EQLLREERE 1129
Query: 316 SDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMS 375
R E+++ Y + + ++ L ++ P L+R R L +E+ L
Sbjct: 1130 KRRRQELERQYREEEEVQQE--EEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 376 LPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPA 435
+ Q E + + +EE++R++ +R R E+++S L + + ++R
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRY-------RDEDQRSDLKWQWEPEKENAVRDNKV 1240
Query: 436 PL--RKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQ 493
R+ E + L Q + S LQ + + + + R E R Q+ R
Sbjct: 1241 YCKGRENEQFRQLEDSQLRDRQSQQDLQHL------LGEQQERDREQERRRWQQRDRHFP 1294
Query: 494 DEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSLDFRE 553
+E +Q + E+ E RR + + E+ Q+LRE E+ R Q + L RE
Sbjct: 1295 EE-EQLEREEQKEAKRRDRKSQ----EEKQLLREEREEKRRRQETDRKFREEEQLLQERE 1349
Query: 554 IGPFQ 558
P +
Sbjct: 1350 EQPLR 1354
Score = 35.8 bits (81), Expect = 0.16
Identities = 36/161 (22%), Positives = 71/161 (44%), Gaps = 18/161 (11%)
Query: 379 KEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLR 438
+++ E + KR++E R + ++R+ QR E++ L R EV L + +
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618
Query: 439 KAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQ 498
+ L + + E LL+ + + R ++R Q+ R+ +
Sbjct: 619 R------LKREEPEEERRQQLLKS---------EEQEERRQQQLRREQQERRE--QRLKR 661
Query: 499 QQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRV 539
++ E+ +E R + E E+ +REQ E+E RER + R+
Sbjct: 662 EEEEERLE-QRLKREHEEERREQELAEEEQEQARERIKSRI 701
Score = 35.8 bits (81), Expect = 0.16
Identities = 44/206 (21%), Positives = 88/206 (42%), Gaps = 36/206 (17%)
Query: 383 EELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEG 442
E+L+ +R+E+ R++ +R+ E Q R E + L S+ ++ + R LR+
Sbjct: 1753 EQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKF----REEEQLRQ--- 1805
Query: 443 WLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRT--LQENLRQLQDEYDQQQ 500
+ E+ QQ R K ++++ ++ LRQ +D + +
Sbjct: 1806 ---------EREEQQLRPQQ--------RDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE 1848
Query: 501 TEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSLDFREIGPFQLE 560
+ A + R+ E+E Q E+ + +ERE + E R + R++G + +
Sbjct: 1849 EQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR----RQQKEEQRHRQVGEIKSQ 1904
Query: 561 PSR------EPRTHLAYALDLGSSPV 580
+ EP TH ++ + SSP+
Sbjct: 1905 EGKGHGRLLEPGTHQFASVPVRSSPL 1930
Score = 33.5 bits (75), Expect = 0.78
Identities = 58/259 (22%), Positives = 104/259 (40%), Gaps = 26/259 (10%)
Query: 383 EELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEG 442
+E + +R+E ++ R + E ++ L+ER+ R L P LR+ E
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDR-KFLEEEPQ-LRRQER 1657
Query: 443 WLPLSGGQGQS-EDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQQQT 501
L + + + + LLQ+ +Q + R + R ++ LR+ + E Q
Sbjct: 1658 EQQLRHDRDRKFREEEQLLQEGEE-----QQLRRQERDRKFREEEQQLRRQERERKFLQE 1712
Query: 502 EKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTRSLDFREIGPFQLEP 561
E+ +L R++ E + + EQL+ E+E R +E++R + + QL P
Sbjct: 1713 EQ--QLRRQELERKFREEEQLRQETEQEQLRRQERYR-------------KILEEEQLRP 1757
Query: 562 SREPRTHLAYALDLGSSPVPSSTAPK-TPSLSSTQPTRVWSGPPAVGQERLPQSSMPQQH 620
RE + D + L S + R + + QER Q PQQ
Sbjct: 1758 EREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 621 EGPSLNPFDEEDLSSPMEE 639
+G ++EE L +E
Sbjct: 1818 DGK--YRWEEEQLQLEEQE 1834
Score = 32.3 bits (72), Expect = 1.7
Identities = 16/58 (27%), Positives = 29/58 (50%)
Query: 486 QENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLH 543
QE R+L + +Q + ++ +E RQ +E+L R++ + E E EQ + H
Sbjct: 142 QEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199
Score = 32.0 bits (71), Expect = 2.3
Identities = 46/185 (24%), Positives = 78/185 (42%), Gaps = 16/185 (8%)
Query: 383 EELKKKRKEEMERKRAVERQAALESQRRLEERQSGL----ASRAANGEVASLRRGPAPLR 438
EE ++ R++E +RK + + E +R+ E + L R E LRR +
Sbjct: 1489 EEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQ 1548
Query: 439 KAEGWLPLSGGQGQ--SEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLRQLQDEY 496
+ + + Q E + L + F + + R ++ R E+ +QL+ +
Sbjct: 1549 RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Query: 497 DQQQTEKAIELSRRQAEEEDLQREQLQMLRERE----LERE---REQFRVASL-HTRTRS 548
QQQ + + R+ E+ +RE+ Q+ R+ LE E R Q R L H R R
Sbjct: 1609 GQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRK 1668
Query: 549 LDFRE 553
FRE
Sbjct: 1669 --FRE 1671
Score = 31.6 bits (70), Expect = 3.0
Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 8/179 (4%)
Query: 367 QEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGE 426
+E+ L K + EE + +R+E + E+Q E R+ E + L R E
Sbjct: 1419 EEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQER----E 1474
Query: 427 VASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQ 486
L R + E L + + + L+ F+ + + R R
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
Query: 487 ENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTR 545
+ +QL+ + QQ + + R+ E+ +RE+ Q+ R+ ER+R +FR+ R
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQ---ERDR-KFRLEEQKVR 1589
Score = 30.4 bits (67), Expect = 6.6
Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 6/65 (9%)
Query: 480 DEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQM------LRERELERE 533
++ R + RQL++E Q++ +K E R AE E+ +Q ++ R+ EL R+
Sbjct: 117 EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
Query: 534 REQFR 538
R++++
Sbjct: 177 RQEWQ 181
Score = 30.0 bits (66), Expect = 8.6
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 474 KAAGRMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQRE-QLQMLRERELER 532
+A G +E R + L + Q++ ++ E RQ EEE QR Q + +EREL
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 533 EREQ 536
EQ
Sbjct: 151 GEEQ 154
>gi|41152097 DNA segment on chromosome X and Y (unique) 155
expressed sequence isoform 1 [Homo sapiens]
Length = 695
Score = 54.3 bits (129), Expect = 4e-07
Identities = 55/197 (27%), Positives = 88/197 (44%), Gaps = 32/197 (16%)
Query: 379 KEQFEELKKKRKEEMERKRAVER-QAALESQRRLEERQSGLASRAANGEVASLRRGPAPL 437
++Q EE K++ KE ER+RA ER Q LE R +R+ L R LRR L
Sbjct: 282 EQQREEQKRREKEAEERQRAEERKQKELEELERERKREEKLRKREQKQRDRELRRNQKKL 341
Query: 438 RKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTL--QENLRQLQDE 495
K Q+E+ L ++I +++E + L Q NL+ ++
Sbjct: 342 EKL-----------QAEEQKQLQEKI--------------KLEERKLLLAQRNLQSIRLI 376
Query: 496 YDQQQTEKAIELSRRQAEEEDL---QREQLQMLRERELER-EREQFRVASLHTRTRSLDF 551
+ KA++L ++ +EE L Q+E+ + L+E EL R E E+ R L + R L
Sbjct: 377 AELLSRAKAVKLREQEQKEEKLRLQQQEERRRLQEAELRRVEEEKERALGLQRKERELRE 436
Query: 552 REIGPFQLEPSREPRTH 568
R + + + TH
Sbjct: 437 RLLSILLSKKPDDSHTH 453
Score = 30.4 bits (67), Expect = 6.6
Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 8/73 (10%)
Query: 467 TSFIRQAKAAGRMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLR 526
T + A R E + LQE L Q ++E Q++ EK E RQ EE Q+E ++ R
Sbjct: 260 TKHLSDASIKKRQLERQKLQE-LEQQREE--QKRREK--EAEERQRAEERKQKELEELER 314
Query: 527 ERELE---REREQ 536
ER+ E R+REQ
Sbjct: 315 ERKREEKLRKREQ 327
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 53.9 bits (128), Expect = 6e-07
Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 11/99 (11%)
Query: 114 IDHYVVEVNKLIIRLEKLTA----FDRTNTESAKIRAIEKSVVPWVNDQDVPFCPDCGNK 169
I+ +V +L +L+ TA R N +S +I+ + W D +V C CG
Sbjct: 1306 IEKLQTKVLELQRKLDNTTAAVQELGREN-QSLQIKHTQALNRKWAEDNEVQNCMACGKG 1364
Query: 170 FSIRNRRHHCRLCGSIMCKKCMELISLPLANKLTSASKE 208
FS+ RRHHCR CG+I C +C N LT +SK+
Sbjct: 1365 FSVTVRRHHCRQCGNIFCAEC------SAKNALTPSSKK 1397
Score = 48.1 bits (113), Expect = 3e-05
Identities = 136/669 (20%), Positives = 252/669 (37%), Gaps = 126/669 (18%)
Query: 12 EGFLCPLCLKDLQSFYQLHSHYEEEHSG------------------------EDRDVKGQ 47
EGF+CP C+K L S +L HYE H E +D++
Sbjct: 39 EGFICPQCMKSLGSADELFKHYEAVHDAGNDSGHGGESNLALKRDDVTLLRQEVQDLQAS 98
Query: 48 IKSLVQKAKKAKDRLLKREGDDRAESGTQGY---ESFSYGGVDPYMWEPQELGAVRSHLS 104
+K +++ K L K +G + E+ G S ++ + E Q +
Sbjct: 99 LKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQLEEAQTENFNIKQMK 158
Query: 105 DFKKHRAARIDHYVVEVNKLI--------IRLEKLTAF-DRTNTESAKIRAIEKSVV--P 153
D + +AA++ + ++ +K+T + N E+ I+ ++ ++ P
Sbjct: 159 DLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRP 218
Query: 154 WVND-----QDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELISLPLANKLTSASKE 208
+ D +++ + ++ R +L CKK L ++ S+
Sbjct: 219 GIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDE--CKK--------LQSQYASSEAT 268
Query: 209 SLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDTLLKREQ---Q 265
+ ++ P V + SSV+ + + + LLK+EQ +
Sbjct: 269 ISQLRSELAKGPQEVAVYVQELQKLKSSVNELTQKNQT--------LTENLLKKEQDYTK 320
Query: 266 IDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHA--SDLRVEVQ 323
++EK + + K + + QK + ++ + L+A ET+ H S+ Q
Sbjct: 321 LEEKHNEESVSK-----KNIQATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGEATQ 375
Query: 324 KVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMS--LPTKEQ 381
K+ E + + K Q L+ QR + L +Q ++ L S L T+ Q
Sbjct: 376 KLKEELSEVETKY------QHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETERQ 429
Query: 382 FEE----LKKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANG------------ 425
E LK++R+ E+ E+Q A + Q +L + L + N
Sbjct: 430 LGEAHGRLKEQRQLSSEKLMDKEQQVA-DLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQ 488
Query: 426 ----EVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAK------A 475
+ A + A LR+A+ L Q D D Q+I N+ + ++++K
Sbjct: 489 QHQEQQALQQSTTAKLREAQN--DLEQVLRQIGDKD---QKIQNLEALLQKSKENISLLE 543
Query: 476 AGRMDEVRTLQEN------LRQLQDEYD--QQQTEKAIELSRRQAEEEDLQREQL-QMLR 526
R D +Q L QLQ++ Q+Q + E + Q+E +E L ++
Sbjct: 544 KEREDLYAKIQAGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQ 603
Query: 527 ERELEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAP 586
E++ Q RV SL T L+ QL S+E + L + + + S+ A
Sbjct: 604 EQKAHLRAAQDRVLSLETSVNELN------SQLNESKEKVSQLDIQIKAKTELLLSAEAA 657
Query: 587 KTPSLSSTQ 595
KT + Q
Sbjct: 658 KTAQRADLQ 666
Score = 38.5 bits (88), Expect = 0.024
Identities = 71/329 (21%), Positives = 138/329 (41%), Gaps = 51/329 (15%)
Query: 256 KDTLLKREQQIDEKEHTPDIV--KLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLE 313
++ L ++Q++++ D V KL +K C + ++ EY SL + T LE
Sbjct: 673 QNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQ-LESHLKEYKEKYLSLE--QKTEELE 729
Query: 314 ------HASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQ 367
A L V+ K L D ++ L L L +++ I S L +Q
Sbjct: 730 GQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQ 789
Query: 368 EKLLGLMSLPTK------------EQFEELKKKRKEEME-------------RKRAVERQ 402
+K L S+ K + FE L ++ K + E +K +E++
Sbjct: 790 KKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKE 849
Query: 403 AALESQRRLEERQSGLASRAANGEVA---SLRRGPAPLRKAEGWLPLSGGQGQSEDSDPL 459
A + ++++ S ++ N + ++G A + E Q Q + + L
Sbjct: 850 ALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKELKHQLQVQMENTL 909
Query: 460 LQQIHNITSFIRQAKAAGRMD-EVRTLQENLRQLQD-----EYDQQQTEKAIELSRRQAE 513
+Q S ++ +A+ ++ E+ ++QE L Q Q+ E ++QQ + I ++ +E
Sbjct: 910 KEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQNEKEEQQLQGNINELKQSSE 969
Query: 514 EEDLQREQLQ------MLRERELEREREQ 536
++ Q E LQ +L++ ELE + +Q
Sbjct: 970 QKKKQIEALQGELKIAVLQKTELENKLQQ 998
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 52.4 bits (124), Expect = 2e-06
Identities = 38/148 (25%), Positives = 60/148 (40%), Gaps = 28/148 (18%)
Query: 63 LKREGDDRAESGTQGYESFSYGGVDPYMWEPQELGAVRS------HLSDFKKHRAARID- 115
L R +RAE G + S P + P +VRS L++ + R++ +D
Sbjct: 52 LFRFNKERAEGGQGEQQPLSGSWTSPQL--PSRTQSVRSPTPYKKQLNEELQRRSSALDT 109
Query: 116 -------------HYVVEVNKLIIRLEKLTAFDRTNTESAKIRAIEKSVVPWVNDQDVPF 162
V++ L L++L ++ + ++ W+ D
Sbjct: 110 RRKAEPTFGGHDPRTAVQLRSLSTVLKRLKEIMEGKSQDSDLKQY------WMPDSQCKE 163
Query: 163 CPDCGNKFSIRNRRHHCRLCGSIMCKKC 190
C DC KF+ RRHHCRLCG I C +C
Sbjct: 164 CYDCSEKFTTFRRRHHCRLCGQIFCSRC 191
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 52.0 bits (123), Expect = 2e-06
Identities = 84/391 (21%), Positives = 155/391 (39%), Gaps = 58/391 (14%)
Query: 386 KKKRKEEMERKRAVERQAALESQRRLEERQSGLASRAANGEV------------ASLRRG 433
KK K+E ERK+ E +A L + EE ++G ++ E ++ G
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTG 290
Query: 434 PAPLRKAEGWLPLSG---GQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQENLR 490
P + + P + +G + D ++ + K + V+ +QE L
Sbjct: 291 VIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT-VKAMQEALA 349
Query: 491 QLQDEYDQQQTE------KAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHT 544
+L++E ++Q+ E + EL ++ EEE L++E+ + +++E ER+ + L T
Sbjct: 350 KLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLT 409
Query: 545 RT-RSLDFREIGPFQL-------EPSRE--PRTHLAYALDLGSSPVPSSTAPKTPSLSST 594
++ R R +L PS++ P+ Y D +P K S S
Sbjct: 410 KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYE-DKKRKKIPQQLESKEVSESME 468
Query: 595 QPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPAAGVSLDPS 654
V E + Q ++ P + P +EED E+A A S + +
Sbjct: 469 LCAAV---------EVMEQGVPEKEETPPPVEPEEEED----TEDAGLDDWEAMASDEET 515
Query: 655 ARI--------LKEYNPFEEEDEEEEAVAGNPFIQPDSPAPNPFSEEDEHPQQRLSSPLV 706
++ +KE NP EEE+EEEE + + E + +++S
Sbjct: 516 EKVEGNKVHIEVKE-NPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKD 574
Query: 707 PGNPFEEPTCINPFEMDSDSGPEAEEPIEEE 737
G ++ EM SDS ++++ +E
Sbjct: 575 SGKTLDKKP---SKEMSSDSEYDSDDDRTKE 602
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 51.6 bits (122), Expect = 3e-06
Identities = 81/359 (22%), Positives = 147/359 (40%), Gaps = 42/359 (11%)
Query: 199 ANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDT 258
A T K S T+ S +S S+ ++ SSV + ++ I K
Sbjct: 42 AGAKTKKKKTDSSPETTTSGGGHSPGDSQYQELAVALESSSVTINQLNENIESLKQQKKQ 101
Query: 259 L---LKREQQIDEKEHTPDIVKLYEKLRLCMEKVDQKAPEYIRMAASLNAGETTYSLEHA 315
+ L+ ++ + + H + +L L +EK D K Y A+ + E + L A
Sbjct: 102 VEHQLEEAKKTNNEIHKAQMEQLETINILTLEKADLKTTLYHTKRAARHFEEESKDL--A 159
Query: 316 SDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLGLMS 375
L+ +Q++ EL ALS + Q S+ R + R + LL
Sbjct: 160 GRLQYSLQRIQELERALS----AVSTQQQEEDRSSSCREAVLQRRLQQTIKERALLNAHV 215
Query: 376 LPTKEQFEELKKKRKE-----EMERKRAVER--QAALESQRRLEERQSGLASRAANGEVA 428
E ++++ +R E + ER R ER + ++E++ EE++ + +
Sbjct: 216 TQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH------RIQ 269
Query: 429 SLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQEN 488
L R + L+ ++ ++P +TS + Q + DE + L++
Sbjct: 270 ELERSLSELK--------------NQMAEPPSLAPPAVTSVVEQLQ-----DEAKHLRQE 310
Query: 489 LRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRTR 547
+ L+ + Q Q E LS E++ +EQ +MLRE+E +R REQ R+ + R R
Sbjct: 311 VEGLEGKL-QSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLR 368
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 51.6 bits (122), Expect = 3e-06
Identities = 52/232 (22%), Positives = 104/232 (44%), Gaps = 16/232 (6%)
Query: 376 LPTKEQFEELKKKRKEEMERKRA-VERQAALESQRRLEERQSGLASRAANGEVASLRRGP 434
L +E+ E++K+++K+++E+K A ++ + + RL E ++ + A E RR
Sbjct: 582 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 641
Query: 435 APLRKAEGWLPLSGG--------QGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQ 486
+ WL Q + E+ L++ Q + R E R Q
Sbjct: 642 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE-Q 700
Query: 487 ENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRT 546
E Q + E ++++ E+ + R+ E+E LQ E+ RE+ L ++EQ + L +
Sbjct: 701 ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ-RELEEKK 759
Query: 547 RSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAP-KTPSLSSTQPT 597
+ + + + QL+ +E + A G+S + T ++P+ +S Q T
Sbjct: 760 KKEEQQRLAERQLQEEQEKKAKEA----AGASKALNVTVDVQSPACTSYQMT 807
Score = 30.4 bits (67), Expect = 6.6
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 353 RLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLE 412
R Q ++ L +EK L L + + EE KKK E++R ERQ E +++ +
Sbjct: 726 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKE----EQQRLAERQLQEEQEKKAK 781
Query: 413 ERQSGLASRAAN 424
E AS+A N
Sbjct: 782 EAAG--ASKALN 791
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 51.6 bits (122), Expect = 3e-06
Identities = 52/232 (22%), Positives = 104/232 (44%), Gaps = 16/232 (6%)
Query: 376 LPTKEQFEELKKKRKEEMERKRA-VERQAALESQRRLEERQSGLASRAANGEVASLRRGP 434
L +E+ E++K+++K+++E+K A ++ + + RL E ++ + A E RR
Sbjct: 578 LQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQ 637
Query: 435 APLRKAEGWLPLSGG--------QGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTLQ 486
+ WL Q + E+ L++ Q + R E R Q
Sbjct: 638 EEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERRE-Q 696
Query: 487 ENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTRT 546
E Q + E ++++ E+ + R+ E+E LQ E+ RE+ L ++EQ + L +
Sbjct: 697 ERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQ-RELEEKK 755
Query: 547 RSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAP-KTPSLSSTQPT 597
+ + + + QL+ +E + A G+S + T ++P+ +S Q T
Sbjct: 756 KKEEQQRLAERQLQEEQEKKAKEA----AGASKALNVTVDVQSPACTSYQMT 803
Score = 30.4 bits (67), Expect = 6.6
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 6/72 (8%)
Query: 353 RLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRAVERQAALESQRRLE 412
R Q ++ L +EK L L + + EE KKK E++R ERQ E +++ +
Sbjct: 722 REQERLQAERELQEREKALRLQKEQLQRELEEKKKKE----EQQRLAERQLQEEQEKKAK 777
Query: 413 ERQSGLASRAAN 424
E AS+A N
Sbjct: 778 EAAG--ASKALN 787
>gi|31317270 WD repeat and FYVE domain containing 3 isoform 3 [Homo
sapiens]
Length = 281
Score = 51.2 bits (121), Expect = 4e-06
Identities = 24/74 (32%), Positives = 35/74 (47%)
Query: 154 WVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELISLPLANKLTSASKESLSTH 213
WV D+ C C +FS+ RRHHCR CG + C+KC S K++S + + +
Sbjct: 206 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 265
Query: 214 TSPSQSPNSVHGSR 227
+ S G R
Sbjct: 266 YNLQHERGSEDGPR 279
>gi|31317272 WD repeat and FYVE domain containing 3 isoform 1 [Homo
sapiens]
Length = 3526
Score = 51.2 bits (121), Expect = 4e-06
Identities = 24/74 (32%), Positives = 35/74 (47%)
Query: 154 WVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMELISLPLANKLTSASKESLSTH 213
WV D+ C C +FS+ RRHHCR CG + C+KC S K++S + + +
Sbjct: 3451 WVKDEGGDSCSGCSVRFSLTERRHHCRNCGQLFCQKCSRFQSEIKRLKISSPVRVCQNCY 3510
Query: 214 TSPSQSPNSVHGSR 227
+ S G R
Sbjct: 3511 YNLQHERGSEDGPR 3524
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 51.2 bits (121), Expect = 4e-06
Identities = 82/362 (22%), Positives = 148/362 (40%), Gaps = 48/362 (13%)
Query: 199 ANKLTSASKESLSTHTSPSQSPNSVHGSRRGSISSMSSVSSVLDEKDDDRIRCCTHCKDT 258
A T K S T+ S +S S+ ++ SSV + ++ I K
Sbjct: 42 AGAKTKKKKTDSSPETTTSGGCHSPGDSQYQELAVALESSSVTISQLNENIESLKQQKKQ 101
Query: 259 LLKREQQIDEKEHTPDIVKLYEKLRL------CMEKVDQKAPEYIRMAASLNAGETTYSL 312
+ E Q++E + T + + + RL +EK D K Y A+ + E + L
Sbjct: 102 V---EHQLEEAKKTNNEIHKAQMERLETINILTLEKADLKTTLYHTKRAARHFEEESKDL 158
Query: 313 EHASDLRVEVQKVYELIDALSKKILTLGLNQDPPPHPSNLRLQRMIRYSATLFVQEKLLG 372
A L+ +Q++ EL AL + Q S+ R + R+ + LL
Sbjct: 159 --AGRLQYSLQRIQELERALC----AVSTQQQEEDRSSSCREAVLQRWLQQTIKERALLN 212
Query: 373 LMSLPTKEQFEELKKKRKE-----EMERKRAVER--QAALESQRRLEERQSGLASRAANG 425
E ++++ +R E + ER R ER + ++E++ EE++ +
Sbjct: 213 AHVTQVTESLKQVQLERDEYAKHIKGERARWQERMWKMSVEARTLKEEKKRDIH------ 266
Query: 426 EVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIHNITSFIRQAKAAGRMDEVRTL 485
+ L R + L+ ++ ++P +TS + Q + DE + L
Sbjct: 267 RIQELERSLSELK--------------NQMAEPPSLAPPAVTSVVEQLQ-----DEAKHL 307
Query: 486 QENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERELEREREQFRVASLHTR 545
++ + L+ + Q Q E LS E++ +EQ +MLRE+E +R REQ R+ + R
Sbjct: 308 RQEVEGLEGKL-QSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNER 366
Query: 546 TR 547
R
Sbjct: 367 LR 368
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 50.8 bits (120), Expect = 5e-06
Identities = 53/207 (25%), Positives = 99/207 (47%), Gaps = 41/207 (19%)
Query: 347 PHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRA--VERQAA 404
P P+ +LQ++ + A QE+ M + + EE ++KR+EE+ R++ + RQ
Sbjct: 713 PGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRRQQEEILRRQQE 768
Query: 405 LESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIH 464
E +RR EE LA R + R LR+ Q E+ + Q+
Sbjct: 769 EERKRREEEE---LARRKQEEALRRQREQEIALRR------------QREEEERQQQE-- 811
Query: 465 NITSFIRQAKAAGRMDEVRTLQENLRQLQDEY------DQQQTEKAIE---------LSR 509
+R+ + R +E R QE L + Q+E ++++ ++ +E +R
Sbjct: 812 ---EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 868
Query: 510 RQAEEEDLQREQLQMLRERELEREREQ 536
+ EEE+ +R++L++ R++EL R+R+Q
Sbjct: 869 LRHEEEERKRKELEVQRQKELMRQRQQ 895
Score = 37.4 bits (85), Expect = 0.054
Identities = 46/200 (23%), Positives = 89/200 (44%), Gaps = 42/200 (21%)
Query: 366 VQEKLLGLMSLPTKEQFEELKKKRKE-EMERKRAV--ERQAALESQRRLEERQSGLASRA 422
++E L + + + EE ++KRKE E++R++ + +RQ E+ RRL+++Q
Sbjct: 855 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ------ 908
Query: 423 ANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQ----IHNITSFIRQAKAAGR 478
++A ++ LP S GQ ++ Q + I + + R
Sbjct: 909 -QQQLAQMK------------LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 955
Query: 479 MDEVRTLQENLRQLQDEYDQQQ--------------TEKAIELSRRQAEEEDLQREQLQM 524
++ R +E ++ LQ + QQQ T K++ L +Q E +Q++Q Q
Sbjct: 956 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL-LEIQQEEARQMQKQQQQQ 1014
Query: 525 LRERELEREREQFRVASLHT 544
+ ++ R R ++LHT
Sbjct: 1015 QQHQQPNRARNNTH-SNLHT 1033
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 50.8 bits (120), Expect = 5e-06
Identities = 53/207 (25%), Positives = 99/207 (47%), Gaps = 41/207 (19%)
Query: 347 PHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRA--VERQAA 404
P P+ +LQ++ + A QE+ M + + EE ++KR+EE+ R++ + RQ
Sbjct: 740 PGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRRQQEEILRRQQE 795
Query: 405 LESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIH 464
E +RR EE LA R + R LR+ Q E+ + Q+
Sbjct: 796 EERKRREEEE---LARRKQEEALRRQREQEIALRR------------QREEEERQQQE-- 838
Query: 465 NITSFIRQAKAAGRMDEVRTLQENLRQLQDEY------DQQQTEKAIE---------LSR 509
+R+ + R +E R QE L + Q+E ++++ ++ +E +R
Sbjct: 839 ---EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 895
Query: 510 RQAEEEDLQREQLQMLRERELEREREQ 536
+ EEE+ +R++L++ R++EL R+R+Q
Sbjct: 896 LRHEEEERKRKELEVQRQKELMRQRQQ 922
Score = 37.4 bits (85), Expect = 0.054
Identities = 46/200 (23%), Positives = 89/200 (44%), Gaps = 42/200 (21%)
Query: 366 VQEKLLGLMSLPTKEQFEELKKKRKE-EMERKRAV--ERQAALESQRRLEERQSGLASRA 422
++E L + + + EE ++KRKE E++R++ + +RQ E+ RRL+++Q
Sbjct: 882 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ------ 935
Query: 423 ANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQ----IHNITSFIRQAKAAGR 478
++A ++ LP S GQ ++ Q + I + + R
Sbjct: 936 -QQQLAQMK------------LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 982
Query: 479 MDEVRTLQENLRQLQDEYDQQQ--------------TEKAIELSRRQAEEEDLQREQLQM 524
++ R +E ++ LQ + QQQ T K++ L +Q E +Q++Q Q
Sbjct: 983 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL-LEIQQEEARQMQKQQQQQ 1041
Query: 525 LRERELEREREQFRVASLHT 544
+ ++ R R ++LHT
Sbjct: 1042 QQHQQPNRARNNTH-SNLHT 1060
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 50.8 bits (120), Expect = 5e-06
Identities = 53/207 (25%), Positives = 99/207 (47%), Gaps = 41/207 (19%)
Query: 347 PHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRA--VERQAA 404
P P+ +LQ++ + A QE+ M + + EE ++KR+EE+ R++ + RQ
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRRQQEEILRRQQE 774
Query: 405 LESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIH 464
E +RR EE LA R + R LR+ Q E+ + Q+
Sbjct: 775 EERKRREEEE---LARRKQEEALRRQREQEIALRR------------QREEEERQQQE-- 817
Query: 465 NITSFIRQAKAAGRMDEVRTLQENLRQLQDEY------DQQQTEKAIE---------LSR 509
+R+ + R +E R QE L + Q+E ++++ ++ +E +R
Sbjct: 818 ---EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
Query: 510 RQAEEEDLQREQLQMLRERELEREREQ 536
+ EEE+ +R++L++ R++EL R+R+Q
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQQ 901
Score = 37.4 bits (85), Expect = 0.054
Identities = 46/200 (23%), Positives = 89/200 (44%), Gaps = 42/200 (21%)
Query: 366 VQEKLLGLMSLPTKEQFEELKKKRKE-EMERKRAV--ERQAALESQRRLEERQSGLASRA 422
++E L + + + EE ++KRKE E++R++ + +RQ E+ RRL+++Q
Sbjct: 861 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ------ 914
Query: 423 ANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQ----IHNITSFIRQAKAAGR 478
++A ++ LP S GQ ++ Q + I + + R
Sbjct: 915 -QQQLAQMK------------LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 961
Query: 479 MDEVRTLQENLRQLQDEYDQQQ--------------TEKAIELSRRQAEEEDLQREQLQM 524
++ R +E ++ LQ + QQQ T K++ L +Q E +Q++Q Q
Sbjct: 962 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL-LEIQQEEARQMQKQQQQQ 1020
Query: 525 LRERELEREREQFRVASLHT 544
+ ++ R R ++LHT
Sbjct: 1021 QQHQQPNRARNNTH-SNLHT 1039
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 50.8 bits (120), Expect = 5e-06
Identities = 53/207 (25%), Positives = 99/207 (47%), Gaps = 41/207 (19%)
Query: 347 PHPSNLRLQRMIRYSATLFVQEKLLGLMSLPTKEQFEELKKKRKEEMERKRA--VERQAA 404
P P+ +LQ++ + A QE+ M + + EE ++KR+EE+ R++ + RQ
Sbjct: 719 PGPALEQLQQLEKAKAAKLEQERREAEM----RAKREEEERKRQEELRRQQEEILRRQQE 774
Query: 405 LESQRRLEERQSGLASRAANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQIH 464
E +RR EE LA R + R LR+ Q E+ + Q+
Sbjct: 775 EERKRREEEE---LARRKQEEALRRQREQEIALRR------------QREEEERQQQE-- 817
Query: 465 NITSFIRQAKAAGRMDEVRTLQENLRQLQDEY------DQQQTEKAIE---------LSR 509
+R+ + R +E R QE L + Q+E ++++ ++ +E +R
Sbjct: 818 ---EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874
Query: 510 RQAEEEDLQREQLQMLRERELEREREQ 536
+ EEE+ +R++L++ R++EL R+R+Q
Sbjct: 875 LRHEEEERKRKELEVQRQKELMRQRQQ 901
Score = 37.4 bits (85), Expect = 0.054
Identities = 46/200 (23%), Positives = 89/200 (44%), Gaps = 42/200 (21%)
Query: 366 VQEKLLGLMSLPTKEQFEELKKKRKE-EMERKRAV--ERQAALESQRRLEERQSGLASRA 422
++E L + + + EE ++KRKE E++R++ + +RQ E+ RRL+++Q
Sbjct: 861 LEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQ------ 914
Query: 423 ANGEVASLRRGPAPLRKAEGWLPLSGGQGQSEDSDPLLQQ----IHNITSFIRQAKAAGR 478
++A ++ LP S GQ ++ Q + I + + R
Sbjct: 915 -QQQLAQMK------------LPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLR 961
Query: 479 MDEVRTLQENLRQLQDEYDQQQ--------------TEKAIELSRRQAEEEDLQREQLQM 524
++ R +E ++ LQ + QQQ T K++ L +Q E +Q++Q Q
Sbjct: 962 EEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSL-LEIQQEEARQMQKQQQQQ 1020
Query: 525 LRERELEREREQFRVASLHT 544
+ ++ R R ++LHT
Sbjct: 1021 QQHQQPNRARNNTH-SNLHT 1039
>gi|31563330 A-kinase anchor protein 13 isoform 1 [Homo sapiens]
Length = 2817
Score = 50.8 bits (120), Expect = 5e-06
Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 39/230 (16%)
Query: 471 RQAKAAGRMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERE- 529
R+A A R +EV+ Q++L + ++E Q++ +L R +A ++ L+REQ Q+ RE E
Sbjct: 2619 REALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAER 2678
Query: 530 ---LEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAP 586
+ ER+ +V+ HT+ I F P P GS S +P
Sbjct: 2679 LSQRQTERDLCQVSHPHTK-----LMRIPSFFPSPEEPPSPSAPSIAKSGSLDSELSVSP 2733
Query: 587 KTPSLSSTQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPA 646
K S+S T + GP + SS Q ++GP G
Sbjct: 2734 KRNSISRTHKDK---GPFHI------LSSTSQTNKGPE------------------GQSQ 2766
Query: 647 AGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQP-DSPAPNPFSEEDE 695
A S S R+ P E+++++++ QP D PA +E +E
Sbjct: 2767 APASTSASTRLFGLTKPKEKKEKKKKNKTSRS--QPGDGPASEVSAEGEE 2814
>gi|21493031 A-kinase anchor protein 13 isoform 3 [Homo sapiens]
Length = 1058
Score = 50.8 bits (120), Expect = 5e-06
Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 39/230 (16%)
Query: 471 RQAKAAGRMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERE- 529
R+A A R +EV+ Q++L + ++E Q++ +L R +A ++ L+REQ Q+ RE E
Sbjct: 860 REALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAER 919
Query: 530 ---LEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAP 586
+ ER+ +V+ HT+ I F P P GS S +P
Sbjct: 920 LSQRQTERDLCQVSHPHTK-----LMRIPSFFPSPEEPPSPSAPSIAKSGSLDSELSVSP 974
Query: 587 KTPSLSSTQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPA 646
K S+S T + GP + SS Q ++GP G
Sbjct: 975 KRNSISRTHKDK---GPFHI------LSSTSQTNKGPE------------------GQSQ 1007
Query: 647 AGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQP-DSPAPNPFSEEDE 695
A S S R+ P E+++++++ QP D PA +E +E
Sbjct: 1008 APASTSASTRLFGLTKPKEKKEKKKKNKTSRS--QPGDGPASEVSAEGEE 1055
>gi|21493029 A-kinase anchor protein 13 isoform 2 [Homo sapiens]
Length = 2813
Score = 50.8 bits (120), Expect = 5e-06
Identities = 59/230 (25%), Positives = 96/230 (41%), Gaps = 39/230 (16%)
Query: 471 RQAKAAGRMDEVRTLQENLRQLQDEYDQQQTEKAIELSRRQAEEEDLQREQLQMLRERE- 529
R+A A R +EV+ Q++L + ++E Q++ +L R +A ++ L+REQ Q+ RE E
Sbjct: 2615 REALLAQREEEVQQGQQDLEKEREELQQKKGTYQYDLERLRAAQKQLEREQEQLRREAER 2674
Query: 530 ---LEREREQFRVASLHTRTRSLDFREIGPFQLEPSREPRTHLAYALDLGSSPVPSSTAP 586
+ ER+ +V+ HT+ I F P P GS S +P
Sbjct: 2675 LSQRQTERDLCQVSHPHTK-----LMRIPSFFPSPEEPPSPSAPSIAKSGSLDSELSVSP 2729
Query: 587 KTPSLSSTQPTRVWSGPPAVGQERLPQSSMPQQHEGPSLNPFDEEDLSSPMEEATTGPPA 646
K S+S T + GP + SS Q ++GP G
Sbjct: 2730 KRNSISRTHKDK---GPFHI------LSSTSQTNKGPE------------------GQSQ 2762
Query: 647 AGVSLDPSARILKEYNPFEEEDEEEEAVAGNPFIQP-DSPAPNPFSEEDE 695
A S S R+ P E+++++++ QP D PA +E +E
Sbjct: 2763 APASTSASTRLFGLTKPKEKKEKKKKNKTSRS--QPGDGPASEVSAEGEE 2810
>gi|47717112 zinc finger, FYVE domain containing 9 isoform 1 [Homo
sapiens]
Length = 1366
Score = 50.4 bits (119), Expect = 6e-06
Identities = 18/40 (45%), Positives = 21/40 (52%)
Query: 154 WVNDQDVPFCPDCGNKFSIRNRRHHCRLCGSIMCKKCMEL 193
WV D P C C +F+ RRHHCR CG + C C L
Sbjct: 696 WVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSL 735
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,400,777
Number of Sequences: 37866
Number of extensions: 1772166
Number of successful extensions: 15950
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 197
Number of HSP's successfully gapped in prelim test: 766
Number of HSP's that attempted gapping in prelim test: 10294
Number of HSP's gapped (non-prelim): 3954
length of query: 784
length of database: 18,247,518
effective HSP length: 110
effective length of query: 674
effective length of database: 14,082,258
effective search space: 9491441892
effective search space used: 9491441892
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.