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Search of human proteins with 70780381
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]
(481 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens] 972 0.0
gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo sa... 629 e-180
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens] 626 e-179
gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo s... 624 e-179
gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo s... 620 e-178
gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo sa... 590 e-168
gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo s... 570 e-162
gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3 ... 377 e-104
gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4... 376 e-104
gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1 ... 374 e-104
gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2... 374 e-104
gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2 ... 365 e-101
gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1 [... 365 e-101
gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3 ... 363 e-100
gi|225579097 bruno-like 5, RNA binding protein isoform 2 [Homo s... 290 3e-78
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 83 5e-16
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 82 1e-15
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 82 1e-15
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 80 4e-15
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 80 4e-15
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 80 4e-15
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 80 4e-15
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens] 80 4e-15
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 78 2e-14
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3... 74 3e-13
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1... 74 3e-13
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4... 74 3e-13
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [... 74 3e-13
gi|93277070 RNA binding motif protein 45 [Homo sapiens] 74 3e-13
gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting ... 74 4e-13
>gi|70780381 bruno-like 6, RNA binding protein [Homo sapiens]
Length = 481
Score = 973 bits (2514), Expect = 0.0
Identities = 481/481 (100%), Positives = 481/481 (100%)
Query: 1 MAAAPGGSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQ 60
MAAAPGGSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQ
Sbjct: 1 MAAAPGGSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQ 60
Query: 61 DLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPI 120
DLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPI
Sbjct: 61 DLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPI 120
Query: 121 QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVK 180
QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVK
Sbjct: 121 QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVK 180
Query: 181 FGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQMAGHLGAFHPAPLPL 240
FGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQMAGHLGAFHPAPLPL
Sbjct: 181 FGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQMAGHLGAFHPAPLPL 240
Query: 241 GACGAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVAAFSLVAAPLLPAAAANSPPG 300
GACGAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVAAFSLVAAPLLPAAAANSPPG
Sbjct: 241 GACGAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVAAFSLVAAPLLPAAAANSPPG 300
Query: 301 SGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGVADPLQQAYAGM 360
SGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGVADPLQQAYAGM
Sbjct: 301 SGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGVADPLQQAYAGM 360
Query: 361 HHYAAAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFG 420
HHYAAAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFG
Sbjct: 361 HHYAAAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFG 420
Query: 421 AVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDANRP 480
AVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDANRP
Sbjct: 421 AVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDANRP 480
Query: 481 Y 481
Y
Sbjct: 481 Y 481
>gi|13123778 bruno-like 4, RNA binding protein isoform 1 [Homo
sapiens]
Length = 486
Score = 629 bits (1621), Expect = e-180
Identities = 331/503 (65%), Positives = 376/503 (74%), Gaps = 43/503 (8%)
Query: 1 MAAAPGGSAQPAGPGPR-LGFSTADSGVGMSGLNPGPA----VPMKDHDAIKLFVGQIPR 55
MA G A A LG S +G M+GL+ P +PMKDHDAIKLF+GQIPR
Sbjct: 5 MATLANGQADNASLSTNGLGSSPGSAG-HMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPR 63
Query: 56 GLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPG 115
LDE+DLKPLFEEFG+IYELTVLKDR TG+HKGCAFLTYC R+SALKAQSALHEQKTLPG
Sbjct: 64 NLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPG 123
Query: 116 MNRPIQVKPAASEGRG----------EDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTV 165
MNRPIQVKPA SE RG +DRKLFVGML KQQ E+DVRRLF+ FG+IEECT+
Sbjct: 124 MNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTI 183
Query: 166 LRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQ 225
LR PDG SKGCAFVK+ S EAQAAI LHGS+TM GASSSLVVK ADTD+ER +RRMQQ
Sbjct: 184 LRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ 243
Query: 226 MAGHLGAFHPAPLPLGACGAYTTAILQHQAALLAA-AQGPGLGPVAA-VAAQMQHVAAFS 283
MAG +G F+P +P GA GAY A++Q QAAL+A+ AQG L P+AA AAQMQ +AA +
Sbjct: 244 MAGQMGMFNPMAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALN 303
Query: 284 ---LVAAPLLPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLS 340
L AAP+ P + ++PPG +P +P+PIGVNGF L PQ NGQP ++ ++ NG+
Sbjct: 304 MNGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIH 363
Query: 341 PYPAQSPGVADPLQQAYAGMHHYA--AAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNL 398
PYPAQSP ADPLQQAYAG+ YA AAYP+AY +S AFPQ P +PQQQREGPEGCNL
Sbjct: 364 PYPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNL 423
Query: 399 FIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMN 458
FIYHLPQEFGDAEL+Q FLP FGFVSFDNP SAQTAIQAMN
Sbjct: 424 FIYHLPQEFGDAELMQMFLP--------------------FGFVSFDNPASAQTAIQAMN 463
Query: 459 GFQIGMKRLKVQLKRPKDANRPY 481
GFQIGMKRLKVQLKRPKDANRPY
Sbjct: 464 GFQIGMKRLKVQLKRPKDANRPY 486
>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
Length = 465
Score = 626 bits (1615), Expect = e-179
Identities = 318/466 (68%), Positives = 367/466 (78%), Gaps = 25/466 (5%)
Query: 40 MKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDS 99
MK+ DAIKLFVGQIPR L+E+DLKP+FE+FGRI+ELTV+KD+ TGLHKGCAFLTYCARDS
Sbjct: 1 MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDS 60
Query: 100 ALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGH 159
ALKAQSALHEQKTLPGMNRPIQVKPA SE RGEDRKLFVGMLGKQQ +EDVR++F+PFG
Sbjct: 61 ALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGT 120
Query: 160 IEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERA 219
I+ECTVLR PDGTSKGCAFVKF + EAQAAI LH SRT+ GASSSLVVK ADT++ER
Sbjct: 121 IDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERG 180
Query: 220 LRRMQQMAGHLGAFHPAPLPLGACGAYTTAILQHQAALLAAAQGPGLGPVAAVAA-QMQH 278
LRRMQQ+A LG F P L GA AYT A++Q QAAL+ AA L P+A +AA QMQH
Sbjct: 181 LRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQAALV-AAHSAYLSPMATMAAVQMQH 239
Query: 279 VAAFS---LVAAPLLPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLY 335
+AA + L+A P+ P++ ++PP + +PA +GVNG+ P+ Q GQP D LY
Sbjct: 240 MAAINANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALY 299
Query: 336 NNGLSPYPAQSPGV-ADPLQQAYAGMHHYAAAYPSAYAPVSTAFPQQPSAL--------- 385
NG+ PYPAQSP DPLQQAYAGM HY AAYP+AY+ V+ AFPQ P+ +
Sbjct: 300 PNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQPPPPPQ 359
Query: 386 ----------PQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQ 435
QQQREGP+GCN+FIYHLPQEF D+E++Q F+PFG V+SAKVFVDRATNQ
Sbjct: 360 QQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQ 419
Query: 436 SKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 481
SKCFGFVSFDNP SAQ AIQAMNGFQIGMKRLKVQLKRPKDANRPY
Sbjct: 420 SKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY 465
>gi|187761299 bruno-like 4, RNA binding protein isoform 2 [Homo
sapiens]
Length = 485
Score = 624 bits (1608), Expect = e-179
Identities = 327/502 (65%), Positives = 371/502 (73%), Gaps = 42/502 (8%)
Query: 1 MAAAPGGSAQPAGPGPR-LGFSTADSGVGMSGLNPGPA----VPMKDHDAIKLFVGQIPR 55
MA G A A LG S +G M+GL+ P +PMKDHDAIKLF+GQIPR
Sbjct: 5 MATLANGQADNASLSTNGLGSSPGSAG-HMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPR 63
Query: 56 GLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPG 115
LDE+DLKPLFEEFG+IYELTVLKDR TG+HKGCAFLTYC R+SALKAQSALHEQKTLPG
Sbjct: 64 NLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPG 123
Query: 116 MNRPIQVKPAASEGRG----------EDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTV 165
MNRPIQVKPA SE RG +DRKLFVGML KQQ E+DVRRLF+ FG+IEECT+
Sbjct: 124 MNRPIQVKPADSESRGGSSCLRQPPSQDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTI 183
Query: 166 LRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQ 225
LR PDG SKGCAFVK+ S EAQAAI LHGS+TM GASSSLVVK ADTD+ER +RRMQQ
Sbjct: 184 LRGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQ 243
Query: 226 MAGHLGAFHPAPLPLGACGAYTTAILQHQAALLAAAQGPGLGPVAA-VAAQMQHVAAFS- 283
MAG +G F+P +P GA GAY A+ Q A + + AQG L P+AA AAQMQ +AA +
Sbjct: 244 MAGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNM 303
Query: 284 --LVAAPLLPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSP 341
L AAP+ P + ++PPG +P +P+PIGVNGF L PQ NGQP ++ ++ NG+ P
Sbjct: 304 NGLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHP 363
Query: 342 YPAQSPGVADPLQQAYAGMHHYA--AAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLF 399
YPAQSP ADPLQQAYAG+ YA AAYP+AY +S AFPQ P +PQQQREGPEGCNLF
Sbjct: 364 YPAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLF 423
Query: 400 IYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNG 459
IYHLPQEFGDAEL+Q FLP FGFVSFDNP SAQTAIQAMNG
Sbjct: 424 IYHLPQEFGDAELMQMFLP--------------------FGFVSFDNPASAQTAIQAMNG 463
Query: 460 FQIGMKRLKVQLKRPKDANRPY 481
FQIGMKRLKVQLKRPKDANRPY
Sbjct: 464 FQIGMKRLKVQLKRPKDANRPY 485
>gi|187761301 bruno-like 4, RNA binding protein isoform 3 [Homo
sapiens]
Length = 484
Score = 620 bits (1600), Expect = e-178
Identities = 326/501 (65%), Positives = 369/501 (73%), Gaps = 41/501 (8%)
Query: 1 MAAAPGGSAQPAGPGPR-LGFSTADSGVGMSGLNPGPA----VPMKDHDAIKLFVGQIPR 55
MA G A A LG S +G M+GL+ P +PMKDHDAIKLF+GQIPR
Sbjct: 5 MATLANGQADNASLSTNGLGSSPGSAG-HMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPR 63
Query: 56 GLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPG 115
LDE+DLKPLFEEFG+IYELTVLKDR TG+HKGCAFLTYC R+SALKAQSALHEQKTLPG
Sbjct: 64 NLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPG 123
Query: 116 MNRPIQVKPAASEGRG---------EDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVL 166
MNRPIQVKPA SE RG RKLFVGML KQQ E+DVRRLF+ FG+IEECT+L
Sbjct: 124 MNRPIQVKPADSESRGGSSCLRQPPSHRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTIL 183
Query: 167 RSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQM 226
R PDG SKGCAFVK+ S EAQAAI LHGS+TM GASSSLVVK ADTD+ER +RRMQQM
Sbjct: 184 RGPDGNSKGCAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQM 243
Query: 227 AGHLGAFHPAPLPLGACGAYTTAILQHQAALLAAAQGPGLGPVAA-VAAQMQHVAAFS-- 283
AG +G F+P +P GA GAY A+ Q A + + AQG L P+AA AAQMQ +AA +
Sbjct: 244 AGQMGMFNPMAIPFGAYGAYAQAMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMN 303
Query: 284 -LVAAPLLPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPY 342
L AAP+ P + ++PPG +P +P+PIGVNGF L PQ NGQP ++ ++ NG+ PY
Sbjct: 304 GLAAAPMTPTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPY 363
Query: 343 PAQSPGVADPLQQAYAGMHHYA--AAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFI 400
PAQSP ADPLQQAYAG+ YA AAYP+AY +S AFPQ P +PQQQREGPEGCNLFI
Sbjct: 364 PAQSPTAADPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREGPEGCNLFI 423
Query: 401 YHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGF 460
YHLPQEFGDAEL+Q FLP FGFVSFDNP SAQTAIQAMNGF
Sbjct: 424 YHLPQEFGDAELMQMFLP--------------------FGFVSFDNPASAQTAIQAMNGF 463
Query: 461 QIGMKRLKVQLKRPKDANRPY 481
QIGMKRLKVQLKRPKDANRPY
Sbjct: 464 QIGMKRLKVQLKRPKDANRPY 484
>gi|24762232 bruno-like 5, RNA binding protein isoform 1 [Homo
sapiens]
Length = 485
Score = 590 bits (1520), Expect = e-168
Identities = 314/466 (67%), Positives = 350/466 (75%), Gaps = 11/466 (2%)
Query: 25 SGVGMSGLNPGPAVP--MKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRL 82
S VG SG P P MKD DAIKLFVGQIPR LDE+DLKPLFE+FGRIYELTVLKD
Sbjct: 22 SPVGSSGPEPPGGQPDGMKDLDAIKLFVGQIPRHLDEKDLKPLFEQFGRIYELTVLKDPY 81
Query: 83 TGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRG-EDRKLFVGML 141
TG+HKGCAFLTYCARDSA+KAQ+ALHEQKTLPGM RPIQVKPA SE RG DRKLFVGML
Sbjct: 82 TGMHKGCAFLTYCARDSAIKAQTALHEQKTLPGMARPIQVKPADSESRGGRDRKLFVGML 141
Query: 142 GKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMA 201
KQQ EEDV RLFQPFG I+ECTVLR PDG+SKGCAFVKF S EAQAAI LHGS+TM
Sbjct: 142 NKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSKGCAFVKFSSHTEAQAAIHALHGSQTMP 201
Query: 202 GASSSLVVKLADTDRERALRRMQQMAGHLGAFHPA-PLPLGACGAYTTAILQHQAALLAA 260
GASSSLVVK ADTD+ER LRRMQQM G LG P+ LP AY A++Q Q +L+
Sbjct: 202 GASSSLVVKFADTDKERTLRRMQQMVGQLGILTPSLTLPFSPYSAYAQALMQQQTTVLST 261
Query: 261 AQGPGLGP-VAAVAAQMQHVAAFSL---VAAPLLPAAAANSPPGSGPGTLPGLPAPIGVN 316
+ G L P VA +Q + A SL A P+ PA+ +SPP G +PGL API N
Sbjct: 262 S-GSYLSPGVAFSPCHIQQIGAVSLNGLPATPIAPASGLHSPPLLGTTAVPGLVAPI-TN 319
Query: 317 GFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGVADPLQQAYAGMHHYAAAYPSA-YAPVS 375
GF + P G P +T+Y NGL PYPAQSP VA+ L A++G+ Y A YP+A P++
Sbjct: 320 GFAGVVPFPGGHPALETVYANGLVPYPAQSPTVAETLHPAFSGVQQYTAMYPTAAITPIA 379
Query: 376 TAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQ 435
+ PQ P L QQQREGPEGCNLFIYHLPQEFGD EL Q FLPFG ++S+KVF+DRATNQ
Sbjct: 380 HSVPQPPPLLQQQQREGPEGCNLFIYHLPQEFGDTELTQMFLPFGNIISSKVFMDRATNQ 439
Query: 436 SKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY 481
SKCFGFVSFDNP SAQ AIQAMNGFQIGMKRLKVQLKRPKD PY
Sbjct: 440 SKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDPGHPY 485
>gi|187761303 bruno-like 4, RNA binding protein isoform 4 [Homo
sapiens]
Length = 448
Score = 570 bits (1469), Expect = e-162
Identities = 306/493 (62%), Positives = 349/493 (70%), Gaps = 61/493 (12%)
Query: 1 MAAAPGGSAQPAGPGPR-LGFSTADSGVGMSGLNPGPA----VPMKDHDAIKLFVGQIPR 55
MA G A A LG S +G M+GL+ P +PMKDHDAIKLF+GQIPR
Sbjct: 5 MATLANGQADNASLSTNGLGSSPGSAG-HMNGLSHSPGNPSTIPMKDHDAIKLFIGQIPR 63
Query: 56 GLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPG 115
LDE+DLKPLFEEFG+IYELTVLKDR TG+HKGCAFLTYC R+SALKAQSALHEQKTLPG
Sbjct: 64 NLDEKDLKPLFEEFGKIYELTVLKDRFTGMHKGCAFLTYCERESALKAQSALHEQKTLPG 123
Query: 116 MNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKG 175
MNRPIQVKPA SE RGEDRKLFVGML KQQ E+DVRRLF+ FG+IEECT+LR PDG SKG
Sbjct: 124 MNRPIQVKPADSESRGEDRKLFVGMLNKQQSEDDVRRLFEAFGNIEECTILRGPDGNSKG 183
Query: 176 CAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQMAGHLGAFHP 235
CAFVK+ S EAQAAI LHGS+TM GASSSLVVK ADTD+ER +RRMQQMAG +G F+P
Sbjct: 184 CAFVKYSSHAEAQAAINALHGSQTMPGASSSLVVKFADTDKERTMRRMQQMAGQMGMFNP 243
Query: 236 APLPLGACGAYTTAILQHQAALLAA-AQGPGLGPVAA-VAAQMQHVAAFS---LVAAPLL 290
+P GA GAY A++Q QAAL+A+ AQG L P+AA AAQMQ +AA + L AAP+
Sbjct: 244 MAIPFGAYGAYAQALMQQQAALMASVAQGGYLNPMAAFAAAQMQQMAALNMNGLAAAPMT 303
Query: 291 PAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGVA 350
P + ++PPG +P +P+PIGVNGF L PQ NGQP ++ ++ NG+ PYPAQSP A
Sbjct: 304 PTSGGSTPPGITAPAVPSIPSPIGVNGFTGLPPQANGQPAAEAVFANGIHPYPAQSPTAA 363
Query: 351 DPLQQAYAGMHHYA--AAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFG 408
DPLQQAYAG+ YA AAYP+AY +S AFPQ P +PQQQREG
Sbjct: 364 DPLQQAYAGVQQYAGPAAYPAAYGQISQAFPQPPPMIPQQQREG---------------- 407
Query: 409 DAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLK 468
FVSFDNP SAQTAIQAMNGFQIGMKRLK
Sbjct: 408 --------------------------------FVSFDNPASAQTAIQAMNGFQIGMKRLK 435
Query: 469 VQLKRPKDANRPY 481
VQLKRPKDANRPY
Sbjct: 436 VQLKRPKDANRPY 448
>gi|68303647 CUG triplet repeat, RNA binding protein 2 isoform 3
[Homo sapiens]
Length = 508
Score = 377 bits (968), Expect = e-104
Identities = 233/486 (47%), Positives = 295/486 (60%), Gaps = 59/486 (12%)
Query: 42 DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG--LHKGCAFLTYCARDS 99
D DAIK+FVGQIPR E++LK LFE +G +Y++ VL+DR KGC F+T+ R +
Sbjct: 36 DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 95
Query: 100 ALKAQSALHEQKTLPGMNRPIQVKPAASEGRG--EDRKLFVGMLGKQQGEEDVRRLFQPF 157
AL+AQ+ALH KTLPGM+ PIQ+KPA SE EDRKLF+GM+ K+ E D+R +F PF
Sbjct: 96 ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPF 155
Query: 158 GHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRE 217
G IEEC +LR PDG S+GCAFV F ++ AQ AI+ +H S+TM G SS +VVK ADT ++
Sbjct: 156 GQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKD 215
Query: 218 RALRRMQQ-MAGHLGAFHPAP----LPLGACGAYTTAILQH--------------QAALL 258
+ RR+QQ +A + + A LG A+LQ Q A +
Sbjct: 216 KEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGM 275
Query: 259 AAAQGPGLGPVAAVAAQMQHVAAFSLVAAPL-------------LPAAAANSPPGSGP-- 303
A Q L +AA AA Q +A S A PL + A+ NS G+
Sbjct: 276 NALQLQNLATLAAAAAAAQ-TSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNS 334
Query: 304 ----GTLPGLP-APIGVNGFGPLTPQT--NGQPGSDTLYNNGLSPYPAQSPGVADPLQQA 356
GTL GL A +G+N L NG G+ L N + G D L QA
Sbjct: 335 LTSLGTLQGLAGATVGLNNINALAGMAALNGGLGATGLTNG--------TAGTMDALTQA 386
Query: 357 YAGMHHYAAA-YPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQT 415
Y+G+ YAAA P+ Y S + QQ SA Q +EGPEG NLFIYHLPQEFGD +++Q
Sbjct: 387 YSGIQQYAAAALPTLY---SQSLLQQQSAAGSQ-KEGPEGANLFIYHLPQEFGDQDILQM 442
Query: 416 FLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPK 475
F+PFG V+SAKVF+D+ TN SKCFGFVS+DNP SAQ AIQAMNGFQIGMKRLKVQLKR K
Sbjct: 443 FMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSK 502
Query: 476 DANRPY 481
+ ++PY
Sbjct: 503 NDSKPY 508
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 384 ALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATN--QSKCFGF 441
AL + P+ +F+ +P+ + + EL + F P+GAV V DR+ N QSK F
Sbjct: 28 ALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCF 87
Query: 442 VSFDNPTSAQTAIQAMNGFQI--GMKRLKVQLKRPKDANR 479
V+F +A A A++ + GM +Q+K P D+ +
Sbjct: 88 VTFYTRKAALEAQNALHNIKTLPGMHH-PIQMK-PADSEK 125
>gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4
[Homo sapiens]
Length = 488
Score = 376 bits (965), Expect = e-104
Identities = 233/486 (47%), Positives = 294/486 (60%), Gaps = 55/486 (11%)
Query: 42 DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG--LHKGCAFLTYCARDS 99
D DAIK+FVGQIPR E++LK LFE +G +Y++ VL+DR KGC F+T+ R +
Sbjct: 12 DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 71
Query: 100 ALKAQSALHEQKTLPGMNRPIQVKPAASEGRG--EDRKLFVGMLGKQQGEEDVRRLFQPF 157
AL+AQ+ALH KTLPGM+ PIQ+KPA SE EDRKLF+GM+ K+ E D+R +F PF
Sbjct: 72 ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPF 131
Query: 158 GHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRE 217
G IEEC +LR PDG S+GCAFV F ++ AQ AI+ +H S+TM G SS +VVK ADT ++
Sbjct: 132 GQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKD 191
Query: 218 RALRRMQQ-MAGHLGAFHPAP----LPLGACGAYTTAILQH--------------QAALL 258
+ RR+QQ +A + + A LG A+LQ Q A +
Sbjct: 192 KEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGM 251
Query: 259 AAAQGPGLGPVAAVAAQMQHVAAFSLVAAPL-------------LPAAAANSPPGSGP-- 303
A Q L +AA AA Q +A S A PL + A+ NS G+
Sbjct: 252 NALQLQNLATLAAAAAAAQ-TSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNS 310
Query: 304 ----GTLPGLP-APIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQS--PGVADPLQQA 356
GTL GL A +G+N L N S N GL + G D L QA
Sbjct: 311 LTSLGTLQGLAGATVGLNNINALAGTIN----SMAALNGGLGATGLTNGTAGTMDALTQA 366
Query: 357 YAGMHHYAAA-YPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQT 415
Y+G+ YAAA P+ Y S + QQ SA Q +EGPEG NLFIYHLPQEFGD +++Q
Sbjct: 367 YSGIQQYAAAALPTLY---SQSLLQQQSAAGSQ-KEGPEGANLFIYHLPQEFGDQDILQM 422
Query: 416 FLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPK 475
F+PFG V+SAKVF+D+ TN SKCFGFVS+DNP SAQ AIQAMNGFQIGMKRLKVQLKR K
Sbjct: 423 FMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSK 482
Query: 476 DANRPY 481
+ ++PY
Sbjct: 483 NDSKPY 488
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 384 ALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATN--QSKCFGF 441
AL + P+ +F+ +P+ + + EL + F P+GAV V DR+ N QSK F
Sbjct: 4 ALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCF 63
Query: 442 VSFDNPTSAQTAIQAMNGFQI--GMKRLKVQLKRPKDANR 479
V+F +A A A++ + GM +Q+K P D+ +
Sbjct: 64 VTFYTRKAALEAQNALHNIKTLPGMHH-PIQMK-PADSEK 101
>gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1
[Homo sapiens]
Length = 490
Score = 374 bits (961), Expect = e-104
Identities = 233/492 (47%), Positives = 295/492 (59%), Gaps = 65/492 (13%)
Query: 42 DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG--LHKGCAFLTYCARDS 99
D DAIK+FVGQIPR E++LK LFE +G +Y++ VL+DR KGC F+T+ R +
Sbjct: 12 DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 71
Query: 100 ALKAQSALHEQKTLPGMNRPIQVKPAASEGRG--EDRKLFVGMLGKQQGEEDVRRLFQPF 157
AL+AQ+ALH KTLPGM+ PIQ+KPA SE EDRKLF+GM+ K+ E D+R +F PF
Sbjct: 72 ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPF 131
Query: 158 GHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRE 217
G IEEC +LR PDG S+GCAFV F ++ AQ AI+ +H S+TM G SS +VVK ADT ++
Sbjct: 132 GQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKD 191
Query: 218 RALRRMQQ-MAGHLGAFHPAP----LPLGACGAYTTAILQH--------------QAALL 258
+ RR+QQ +A + + A LG A+LQ Q A +
Sbjct: 192 KEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGM 251
Query: 259 AAAQGPGLGPVAAVAAQMQHVAAFSLVAAPL-------------LPAAAANSPPGSGP-- 303
A Q L +AA AA Q +A S A PL + A+ NS G+
Sbjct: 252 NALQLQNLATLAAAAAAAQ-TSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNS 310
Query: 304 ----GTLPGLP-APIGVNGFGPLT--------PQTNGQPGSDTLYNNGLSPYPAQSPGVA 350
GTL GL A +G+N L NG G+ L N + G
Sbjct: 311 LTSLGTLQGLAGATVGLNNINALAVAQMLSGMAALNGGLGATGLTNG--------TAGTM 362
Query: 351 DPLQQAYAGMHHYAAA-YPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGD 409
D L QAY+G+ YAAA P+ Y S + QQ SA Q +EGPEG NLFIYHLPQEFGD
Sbjct: 363 DALTQAYSGIQQYAAAALPTLY---SQSLLQQQSAAGSQ-KEGPEGANLFIYHLPQEFGD 418
Query: 410 AELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKV 469
+++Q F+PFG V+SAKVF+D+ TN SKCFGFVS+DNP SAQ AIQAMNGFQIGMKRLKV
Sbjct: 419 QDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKV 478
Query: 470 QLKRPKDANRPY 481
QLKR K+ ++PY
Sbjct: 479 QLKRSKNDSKPY 490
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 384 ALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATN--QSKCFGF 441
AL + P+ +F+ +P+ + + EL + F P+GAV V DR+ N QSK F
Sbjct: 4 ALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCF 63
Query: 442 VSFDNPTSAQTAIQAMNGFQI--GMKRLKVQLKRPKDANR 479
V+F +A A A++ + GM +Q+K P D+ +
Sbjct: 64 VTFYTRKAALEAQNALHNIKTLPGMHH-PIQMK-PADSEK 101
>gi|134152680 CUG triplet repeat, RNA binding protein 2 isoform 2
[Homo sapiens]
Length = 521
Score = 374 bits (961), Expect = e-104
Identities = 233/492 (47%), Positives = 295/492 (59%), Gaps = 65/492 (13%)
Query: 42 DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG--LHKGCAFLTYCARDS 99
D DAIK+FVGQIPR E++LK LFE +G +Y++ VL+DR KGC F+T+ R +
Sbjct: 43 DPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKA 102
Query: 100 ALKAQSALHEQKTLPGMNRPIQVKPAASEGRG--EDRKLFVGMLGKQQGEEDVRRLFQPF 157
AL+AQ+ALH KTLPGM+ PIQ+KPA SE EDRKLF+GM+ K+ E D+R +F PF
Sbjct: 103 ALEAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPF 162
Query: 158 GHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRE 217
G IEEC +LR PDG S+GCAFV F ++ AQ AI+ +H S+TM G SS +VVK ADT ++
Sbjct: 163 GQIEECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKD 222
Query: 218 RALRRMQQ-MAGHLGAFHPAP----LPLGACGAYTTAILQH--------------QAALL 258
+ RR+QQ +A + + A LG A+LQ Q A +
Sbjct: 223 KEQRRLQQQLAQQMQQLNTATWGNLTGLGGLTPQYLALLQQATSSSNLGAFSGIQQMAGM 282
Query: 259 AAAQGPGLGPVAAVAAQMQHVAAFSLVAAPL-------------LPAAAANSPPGSGP-- 303
A Q L +AA AA Q +A S A PL + A+ NS G+
Sbjct: 283 NALQLQNLATLAAAAAAAQ-TSATSTNANPLSTTSSALGALTSPVAASTPNSTAGAAMNS 341
Query: 304 ----GTLPGLP-APIGVNGFGPLT--------PQTNGQPGSDTLYNNGLSPYPAQSPGVA 350
GTL GL A +G+N L NG G+ L N + G
Sbjct: 342 LTSLGTLQGLAGATVGLNNINALAVAQMLSGMAALNGGLGATGLTNG--------TAGTM 393
Query: 351 DPLQQAYAGMHHYAAA-YPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGD 409
D L QAY+G+ YAAA P+ Y S + QQ SA Q +EGPEG NLFIYHLPQEFGD
Sbjct: 394 DALTQAYSGIQQYAAAALPTLY---SQSLLQQQSAAGSQ-KEGPEGANLFIYHLPQEFGD 449
Query: 410 AELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKV 469
+++Q F+PFG V+SAKVF+D+ TN SKCFGFVS+DNP SAQ AIQAMNGFQIGMKRLKV
Sbjct: 450 QDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKV 509
Query: 470 QLKRPKDANRPY 481
QLKR K+ ++PY
Sbjct: 510 QLKRSKNDSKPY 521
Score = 43.1 bits (100), Expect = 6e-04
Identities = 31/100 (31%), Positives = 51/100 (51%), Gaps = 6/100 (6%)
Query: 384 ALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATN--QSKCFGF 441
AL + P+ +F+ +P+ + + EL + F P+GAV V DR+ N QSK F
Sbjct: 35 ALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCF 94
Query: 442 VSFDNPTSAQTAIQAMNGFQI--GMKRLKVQLKRPKDANR 479
V+F +A A A++ + GM +Q+K P D+ +
Sbjct: 95 VTFYTRKAALEAQNALHNIKTLPGMHH-PIQMK-PADSEK 132
>gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2
[Homo sapiens]
Length = 483
Score = 365 bits (938), Expect = e-101
Identities = 227/497 (45%), Positives = 289/497 (58%), Gaps = 58/497 (11%)
Query: 29 MSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG--LH 86
M+G P P D DAIK+FVGQ+PR E+DL+ LFE++G +YE+ VL+DR
Sbjct: 1 MNGTLDHPDQP--DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQS 58
Query: 87 KGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRG--EDRKLFVGMLGKQ 144
KGC F+T+ R +AL+AQ+ALH K LPGM+ PIQ+KPA SE EDRKLF+GM+ K+
Sbjct: 59 KGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKK 118
Query: 145 QGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGAS 204
E D+R +F FG IEEC +LR PDG S+GCAFV F ++ AQ AI+ +H ++TM G S
Sbjct: 119 CTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCS 178
Query: 205 SSLVVKLADTDRERALRRMQQ-----------------MAGHLGAFHPAPLPL----GAC 243
S +VVK ADT +++ +RM Q +AG L P L L +
Sbjct: 179 SPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAG-LNTLGPQYLALLQQTASS 237
Query: 244 GAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVA----AFSLVAAPL--LPAAAANS 297
G T H L A Q L +AA A+ Q+ A + ++PL L ++A +S
Sbjct: 238 GNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSAGSS 297
Query: 298 PPGSGPG------------TLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQ 345
P S TL G A + V + NG GS L N S A
Sbjct: 298 PSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAA-LNGGLGSSGLSNGTGSTMEA- 355
Query: 346 SPGVADPLQQAYAGMHHYAAA-YPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLP 404
L QAY+G+ YAAA P+ Y QQ Q+EGPEG NLFIYHLP
Sbjct: 356 -------LTQAYSGIQQYAAAALPTLYN--QNLLTQQSIGAAGSQKEGPEGANLFIYHLP 406
Query: 405 QEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGM 464
QEFGD +L+Q F+PFG VVSAKVF+D+ TN SKCFGFVS+DNP SAQ AIQ+MNGFQIGM
Sbjct: 407 QEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGM 466
Query: 465 KRLKVQLKRPKDANRPY 481
KRLKVQLKR K+ ++PY
Sbjct: 467 KRLKVQLKRSKNDSKPY 483
>gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1
[Homo sapiens]
Length = 482
Score = 365 bits (937), Expect = e-101
Identities = 225/496 (45%), Positives = 286/496 (57%), Gaps = 57/496 (11%)
Query: 29 MSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG--LH 86
M+G P P D DAIK+FVGQ+PR E+DL+ LFE++G +YE+ VL+DR
Sbjct: 1 MNGTLDHPDQP--DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQS 58
Query: 87 KGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRG--EDRKLFVGMLGKQ 144
KGC F+T+ R +AL+AQ+ALH K LPGM+ PIQ+KPA SE EDRKLF+GM+ K+
Sbjct: 59 KGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKK 118
Query: 145 QGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGAS 204
E D+R +F FG IEEC +LR PDG S+GCAFV F ++ AQ AI+ +H ++TM G S
Sbjct: 119 CTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCS 178
Query: 205 SSLVVKLADTDRERALRRMQQ-----------------MAGHLGAFHPAPLPL----GAC 243
S +VVK ADT +++ +RM Q +AG L P L L +
Sbjct: 179 SPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAG-LNTLGPQYLALLQQTASS 237
Query: 244 GAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVA----AFSLVAAPLLPAAAANSPP 299
G T H L A Q L +AA A+ Q+ A + ++PL ++ S P
Sbjct: 238 GNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSSGSSP 297
Query: 300 GSGPG-------------TLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQS 346
S TL G A + V + NG GS L N S A
Sbjct: 298 SSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAA-LNGGLGSSGLSNGTGSTMEA-- 354
Query: 347 PGVADPLQQAYAGMHHYAAA-YPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQ 405
L QAY+G+ YAAA P+ Y QQ Q+EGPEG NLFIYHLPQ
Sbjct: 355 ------LTQAYSGIQQYAAAALPTLYN--QNLLTQQSIGAAGSQKEGPEGANLFIYHLPQ 406
Query: 406 EFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMK 465
EFGD +L+Q F+PFG VVSAKVF+D+ TN SKCFGFVS+DNP SAQ AIQ+MNGFQIGMK
Sbjct: 407 EFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQIGMK 466
Query: 466 RLKVQLKRPKDANRPY 481
RLKVQLKR K+ ++PY
Sbjct: 467 RLKVQLKRSKNDSKPY 482
>gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3
[Homo sapiens]
Length = 486
Score = 363 bits (933), Expect = e-100
Identities = 225/500 (45%), Positives = 286/500 (57%), Gaps = 61/500 (12%)
Query: 29 MSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG--LH 86
M+G P P D DAIK+FVGQ+PR E+DL+ LFE++G +YE+ VL+DR
Sbjct: 1 MNGTLDHPDQP--DLDAIKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQS 58
Query: 87 KGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRG--EDRKLFVGMLGKQ 144
KGC F+T+ R +AL+AQ+ALH K LPGM+ PIQ+KPA SE EDRKLF+GM+ K+
Sbjct: 59 KGCCFVTFYTRKAALEAQNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKK 118
Query: 145 QGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGAS 204
E D+R +F FG IEEC +LR PDG S+GCAFV F ++ AQ AI+ +H ++TM G S
Sbjct: 119 CTENDIRVMFSSFGQIEECRILRGPDGLSRGCAFVTFTTRAMAQTAIKAMHQAQTMEGCS 178
Query: 205 SSLVVKLADTDRERALRRMQQ-----------------MAGHLGAFHPAPLPL------- 240
S +VVK ADT +++ +RM Q +AG L P L L
Sbjct: 179 SPMVVKFADTQKDKEQKRMAQQLQQQMQQISAASVWGNLAG-LNTLGPQYLALYLQLLQQ 237
Query: 241 -GACGAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVA----AFSLVAAPLLPAAAA 295
+ G T H L A Q L +AA A+ Q+ A + ++PL ++
Sbjct: 238 TASSGNLNTLSSLHPMGGLNAMQLQNLAALAAAASAAQNTPSGTNALTTSSSPLSVLTSS 297
Query: 296 NSPPGSGPG-------------TLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPY 342
S P S TL G A + V + NG GS L N S
Sbjct: 298 GSSPSSSSSNSVNPIASLGALQTLAGATAGLNVGSLAGMAA-LNGGLGSSGLSNGTGSTM 356
Query: 343 PAQSPGVADPLQQAYAGMHHYAAA-YPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIY 401
A L QAY+G+ YAAA P+ Y QQ Q+EGPEG NLFIY
Sbjct: 357 EA--------LTQAYSGIQQYAAAALPTLYN--QNLLTQQSIGAAGSQKEGPEGANLFIY 406
Query: 402 HLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQ 461
HLPQEFGD +L+Q F+PFG VVSAKVF+D+ TN SKCFGFVS+DNP SAQ AIQ+MNGFQ
Sbjct: 407 HLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSMNGFQ 466
Query: 462 IGMKRLKVQLKRPKDANRPY 481
IGMKRLKVQLKR K+ ++PY
Sbjct: 467 IGMKRLKVQLKRSKNDSKPY 486
>gi|225579097 bruno-like 5, RNA binding protein isoform 2 [Homo
sapiens]
Length = 320
Score = 290 bits (741), Expect = 3e-78
Identities = 164/284 (57%), Positives = 191/284 (67%), Gaps = 9/284 (3%)
Query: 116 MNRPIQVKPAASEGRG-EDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSK 174
M RPIQVKPA SE RG DRKLFVGML KQQ EEDV RLFQPFG I+ECTVLR PDG+SK
Sbjct: 1 MARPIQVKPADSESRGGRDRKLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGPDGSSK 60
Query: 175 GCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQMAGHLGAFH 234
GCAFVKF S EAQAAI LHGS+TM GASSSLVVK ADTD+ER LRRMQQM G LG
Sbjct: 61 GCAFVKFSSHTEAQAAIHALHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLGILT 120
Query: 235 PA-PLPLGACGAYTTAILQHQAALLAAAQGPGLGP-VAAVAAQMQHVAAFS---LVAAPL 289
P+ LP AY A++Q Q +L+ + G L P VA +Q + A S L A P+
Sbjct: 121 PSLTLPFSPYSAYAQALMQQQTTVLSTS-GSYLSPGVAFSPCHIQQIGAVSLNGLPATPI 179
Query: 290 LPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGV 349
PA+ +SPP G +PGL API NGF + P G P +T+Y NGL PYPAQSP V
Sbjct: 180 APASGLHSPPLLGTTAVPGLVAPI-TNGFAGVVPFPGGHPALETVYANGLVPYPAQSPTV 238
Query: 350 ADPLQQAYAGMHHYAAAYP-SAYAPVSTAFPQQPSALPQQQREG 392
A+ L A++G+ Y A YP +A P++ + PQ P L QQQREG
Sbjct: 239 AETLHPAFSGVQQYTAMYPTAAITPIAHSVPQPPPLLQQQQREG 282
Score = 59.7 bits (143), Expect = 6e-09
Identities = 38/98 (38%), Positives = 55/98 (56%), Gaps = 3/98 (3%)
Query: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSA 106
KLFVG + + E+D+ LF+ FG I E TVL+ G KGCAF+ + + A A A
Sbjct: 21 KLFVGMLNKQQSEEDVLRLFQPFGVIDECTVLRGP-DGSSKGCAFVKFSSHTEAQAAIHA 79
Query: 107 LHEQKTLPGMNRPIQVKPAASEGRGEDRKL--FVGMLG 142
LH +T+PG + + VK A ++ R++ VG LG
Sbjct: 80 LHGSQTMPGASSSLVVKFADTDKERTLRRMQQMVGQLG 117
Score = 37.0 bits (84), Expect = 0.040
Identities = 26/85 (30%), Positives = 41/85 (48%), Gaps = 2/85 (2%)
Query: 377 AFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQS 436
A P Q + R G + LF+ L ++ + ++++ F PFG + V + S
Sbjct: 2 ARPIQVKPADSESRGGRDR-KLFVGMLNKQQSEEDVLRLFQPFGVIDECTV-LRGPDGSS 59
Query: 437 KCFGFVSFDNPTSAQTAIQAMNGFQ 461
K FV F + T AQ AI A++G Q
Sbjct: 60 KGCAFVKFSSHTEAQAAIHALHGSQ 84
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 83.2 bits (204), Expect = 5e-16
Identities = 74/302 (24%), Positives = 139/302 (46%), Gaps = 37/302 (12%)
Query: 22 TADSGVGMSGLNPGPAVPMK-----DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELT 76
T+++ G S N PM+ D L V +P+ + +++ + LF G I
Sbjct: 17 TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 76
Query: 77 VLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKL 136
+++D++TG G F+ Y A KA + L+ + + +P+++ R D L
Sbjct: 77 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR--DANL 134
Query: 137 FVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGSQGEAQAAIRGLH 195
+V L K ++++ +LF +G I +L G S+G F++F + EA+ AI+GL+
Sbjct: 135 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLN 194
Query: 196 GSRTMAGASSSLVVKLADTDRERALRRM-QQMAGHLGAFHPAPLPLGACGAYTTAILQHQ 254
G + +GA+ + VK A+ +++ + + Q+ +P PL HQ
Sbjct: 195 GQKP-SGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPL-------------HHQ 240
Query: 255 AALLAAAQGPGLGPVAAVAAQMQHVAAFSLVAAPLLPAAAANSPPGSGPGTLPGLPAPIG 314
A Q L + +A ++ L++ P+ P+A PP P T+ G+ + +G
Sbjct: 241 A------QRFRLDNLLNMAYGVKR-----LMSGPVPPSAC---PPRFSPITIDGMTSLVG 286
Query: 315 VN 316
+N
Sbjct: 287 MN 288
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/81 (40%), Positives = 49/81 (60%)
Query: 395 GCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAI 454
G +F+Y+L + ++ L Q F PFGAV + KV D TN+ K FGFV+ N A AI
Sbjct: 296 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 355
Query: 455 QAMNGFQIGMKRLKVQLKRPK 475
++NG+++G + L+V K K
Sbjct: 356 ASLNGYRLGDRVLQVSFKTNK 376
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/82 (35%), Positives = 44/82 (53%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL + +LPQ E F G + S K+ D+ T QS +GFV++ +P A+ AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 457 MNGFQIGMKRLKVQLKRPKDAN 478
+NG ++ K +KV RP A+
Sbjct: 107 LNGLRLQTKTIKVSYARPSSAS 128
Score = 51.2 bits (121), Expect = 2e-06
Identities = 22/63 (34%), Positives = 38/63 (60%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL++ LP+ EL Q F +G ++++++ VD+ T S+ GF+ FD A+ AI+
Sbjct: 133 NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKG 192
Query: 457 MNG 459
+NG
Sbjct: 193 LNG 195
Score = 37.7 bits (86), Expect = 0.023
Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 4/102 (3%)
Query: 7 GSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLF 66
G P+ PR T D + G+N +P +FV + DE L LF
Sbjct: 262 GPVPPSACPPRFSPITIDGMTSLVGMN----IPGHTGTGWCIFVYNLSPDSDESVLWQLF 317
Query: 67 EEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALH 108
FG + + V++D T KG F+T D A A ++L+
Sbjct: 318 GPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLN 359
Score = 33.1 bits (74), Expect = 0.57
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 112 TLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRS-PD 170
T+ GM + + G G +FV L E + +LF PFG + V+R
Sbjct: 277 TIDGMTSLVGMNIPGHTGTGWC--IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNT 334
Query: 171 GTSKGCAFVKFGSQGEAQAAIRGLHGSR 198
KG FV + EA AI L+G R
Sbjct: 335 NKCKGFGFVTMTNYDEAAMAIASLNGYR 362
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 82.0 bits (201), Expect = 1e-15
Identities = 60/215 (27%), Positives = 102/215 (47%), Gaps = 22/215 (10%)
Query: 6 GGSAQPAGP-GPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKP 64
GG A PA P GP LG + A D L V +P+ + + + K
Sbjct: 15 GGPAGPALPNGPLLGTNGAT-----------------DDSKTNLIVNYLPQNMTQDEFKS 57
Query: 65 LFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKP 124
LF G I +++D++TG G F+ Y + A KA + L+ K + +P
Sbjct: 58 LFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARP 117
Query: 125 AASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGS 183
+++ R D L+V L K ++++ +LF +G I +L G S+G F++F
Sbjct: 118 SSASIR--DANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 175
Query: 184 QGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRER 218
+ EA+ AI+GL+G + + GA+ + VK A+ ++
Sbjct: 176 RIEAEEAIKGLNGQKPL-GAAEPITVKFANNPSQK 209
Score = 74.3 bits (181), Expect = 2e-13
Identities = 87/366 (23%), Positives = 146/366 (39%), Gaps = 49/366 (13%)
Query: 127 SEGRGEDRK--LFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGS 183
+ G +D K L V L + +++ + LF G IE C ++R G S G FV +
Sbjct: 30 TNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSD 89
Query: 184 QGEAQAAIRGLHGSR--------TMAGASSSLV----VKLADTDRERALRRMQQMAGHLG 231
+A AI L+G + + A SS+ + + ++ + + + M+Q+ G
Sbjct: 90 PNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYG 149
Query: 232 AFHPAPLPLGACGAYTTAI--LQHQAALLAAAQGPGLGPVAAVAAQMQHVAAFSLVAAPL 289
+ + + + + ++ + A GL + A A P+
Sbjct: 150 RIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGA-----------AEPI 198
Query: 290 LPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGV 349
A N +G L L GPL QT + D L N + GV
Sbjct: 199 TVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQ-RFRLDNLLN--------MAYGV 249
Query: 350 ADPLQQAYAGMHHYAAAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGD 409
PL + ++P++ + + G +F+Y+L E +
Sbjct: 250 KSPLSLI------------ARFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADE 297
Query: 410 AELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKV 469
+ L Q F PFGAV + KV D TN+ K FGFV+ N A AI ++NG+++G + L+V
Sbjct: 298 SVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQV 357
Query: 470 QLKRPK 475
K K
Sbjct: 358 SFKTSK 363
Score = 58.9 bits (141), Expect = 1e-08
Identities = 34/101 (33%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 384 ALPQQQREGPEGC------NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSK 437
ALP G G NL + +LPQ E F G + S K+ D+ T QS
Sbjct: 21 ALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSL 80
Query: 438 CFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDAN 478
+GFV++ +P A AI +NG ++ K +KV RP A+
Sbjct: 81 GYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSAS 121
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Query: 48 LFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSAL 107
L+V +P+ + +++++ LF ++GRI +L D++TG+ +G F+ + R A +A L
Sbjct: 127 LYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 108 HEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGH 159
+ QK L G PI VK A + + + L + + RR P H
Sbjct: 187 NGQKPL-GAAEPITVKFANNPSQKTGQALLTHLY-----QSSARRYAGPLHH 232
Score = 33.5 bits (75), Expect = 0.44
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)
Query: 25 SGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG 84
+GVG+SG G +FV + DE L LF FG + + V++D T
Sbjct: 271 AGVGLSGGAAGAGWC--------IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTN 322
Query: 85 LHKGCAFLTYCARDSALKAQSALH 108
KG F+T D A A ++L+
Sbjct: 323 KCKGFGFVTMTNYDEAAMAIASLN 346
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 82.0 bits (201), Expect = 1e-15
Identities = 60/215 (27%), Positives = 102/215 (47%), Gaps = 22/215 (10%)
Query: 6 GGSAQPAGP-GPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKP 64
GG A PA P GP LG + A D L V +P+ + + + K
Sbjct: 15 GGPAGPALPNGPLLGTNGAT-----------------DDSKTNLIVNYLPQNMTQDEFKS 57
Query: 65 LFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKP 124
LF G I +++D++TG G F+ Y + A KA + L+ K + +P
Sbjct: 58 LFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARP 117
Query: 125 AASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGS 183
+++ R D L+V L K ++++ +LF +G I +L G S+G F++F
Sbjct: 118 SSASIR--DANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDK 175
Query: 184 QGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRER 218
+ EA+ AI+GL+G + + GA+ + VK A+ ++
Sbjct: 176 RIEAEEAIKGLNGQKPL-GAAEPITVKFANNPSQK 209
Score = 64.7 bits (156), Expect = 2e-10
Identities = 34/81 (41%), Positives = 49/81 (60%)
Query: 395 GCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAI 454
G +F+Y+L E ++ L Q F PFGAV + KV D TN+ K FGFV+ N A AI
Sbjct: 276 GWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAI 335
Query: 455 QAMNGFQIGMKRLKVQLKRPK 475
++NG+++G + L+V K K
Sbjct: 336 ASLNGYRLGERVLQVSFKTSK 356
Score = 58.9 bits (141), Expect = 1e-08
Identities = 34/101 (33%), Positives = 48/101 (47%), Gaps = 6/101 (5%)
Query: 384 ALPQQQREGPEGC------NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSK 437
ALP G G NL + +LPQ E F G + S K+ D+ T QS
Sbjct: 21 ALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSL 80
Query: 438 CFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKVQLKRPKDAN 478
+GFV++ +P A AI +NG ++ K +KV RP A+
Sbjct: 81 GYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSAS 121
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/112 (28%), Positives = 57/112 (50%), Gaps = 6/112 (5%)
Query: 48 LFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSAL 107
L+V +P+ + +++++ LF ++GRI +L D++TG+ +G F+ + R A +A L
Sbjct: 127 LYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 108 HEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGH 159
+ QK L G PI VK A + + + L + + RR P H
Sbjct: 187 NGQKPL-GAAEPITVKFANNPSQKTGQALLTHLY-----QSSARRYAGPLHH 232
Score = 51.2 bits (121), Expect = 2e-06
Identities = 21/63 (33%), Positives = 38/63 (60%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL++ LP+ E+ Q F +G ++++++ VD+ T S+ GF+ FD A+ AI+
Sbjct: 126 NLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKG 185
Query: 457 MNG 459
+NG
Sbjct: 186 LNG 188
Score = 33.5 bits (75), Expect = 0.44
Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 8/84 (9%)
Query: 25 SGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTG 84
+GVG+SG G +FV + DE L LF FG + + V++D T
Sbjct: 264 AGVGLSGGAAGAGWC--------IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTN 315
Query: 85 LHKGCAFLTYCARDSALKAQSALH 108
KG F+T D A A ++L+
Sbjct: 316 KCKGFGFVTMTNYDEAAMAIASLN 339
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 80.1 bits (196), Expect = 4e-15
Identities = 57/224 (25%), Positives = 109/224 (48%), Gaps = 10/224 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMK-----DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELT 76
T+++ G S N PM+ D L V +P+ + +++ + LF G I
Sbjct: 20 TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 79
Query: 77 VLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKL 136
+++D++TG G F+ Y A KA + L+ + + +P+++ R D L
Sbjct: 80 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR--DANL 137
Query: 137 FVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGSQGEAQAAIRGLH 195
+V L K ++++ +LF +G I +L G S+G F++F + EA+ AI+GL+
Sbjct: 138 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLN 197
Query: 196 GSRTMAGASSSLVVKLADTDRERALRR-MQQMAGHLGAFHPAPL 238
G + +GA+ + VK A+ +++ + + Q+ +P PL
Sbjct: 198 GQKP-SGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPL 240
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/81 (40%), Positives = 49/81 (60%)
Query: 395 GCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAI 454
G +F+Y+L + ++ L Q F PFGAV + KV D TN+ K FGFV+ N A AI
Sbjct: 285 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 344
Query: 455 QAMNGFQIGMKRLKVQLKRPK 475
++NG+++G + L+V K K
Sbjct: 345 ASLNGYRLGDRVLQVSFKTNK 365
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/82 (35%), Positives = 44/82 (53%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL + +LPQ E F G + S K+ D+ T QS +GFV++ +P A+ AI
Sbjct: 50 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 109
Query: 457 MNGFQIGMKRLKVQLKRPKDAN 478
+NG ++ K +KV RP A+
Sbjct: 110 LNGLRLQTKTIKVSYARPSSAS 131
Score = 51.2 bits (121), Expect = 2e-06
Identities = 22/63 (34%), Positives = 38/63 (60%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL++ LP+ EL Q F +G ++++++ VD+ T S+ GF+ FD A+ AI+
Sbjct: 136 NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKG 195
Query: 457 MNG 459
+NG
Sbjct: 196 LNG 198
Score = 33.1 bits (74), Expect = 0.57
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 112 TLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRS-PD 170
T+ GM + + G G +FV L E + +LF PFG + V+R
Sbjct: 266 TIDGMTSLVGMNIPGHTGTGWC--IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNT 323
Query: 171 GTSKGCAFVKFGSQGEAQAAIRGLHGSR 198
KG FV + EA AI L+G R
Sbjct: 324 NKCKGFGFVTMTNYDEAAMAIASLNGYR 351
Score = 32.7 bits (73), Expect = 0.75
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDR 81
T D + G+N +P +FV + DE L LF FG + + V++D
Sbjct: 266 TIDGMTSLVGMN----IPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 321
Query: 82 LTGLHKGCAFLTYCARDSALKAQSALH 108
T KG F+T D A A ++L+
Sbjct: 322 NTNKCKGFGFVTMTNYDEAAMAIASLN 348
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 80.1 bits (196), Expect = 4e-15
Identities = 57/224 (25%), Positives = 109/224 (48%), Gaps = 10/224 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMK-----DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELT 76
T+++ G S N PM+ D L V +P+ + +++ + LF G I
Sbjct: 17 TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 76
Query: 77 VLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKL 136
+++D++TG G F+ Y A KA + L+ + + +P+++ R D L
Sbjct: 77 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR--DANL 134
Query: 137 FVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGSQGEAQAAIRGLH 195
+V L K ++++ +LF +G I +L G S+G F++F + EA+ AI+GL+
Sbjct: 135 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLN 194
Query: 196 GSRTMAGASSSLVVKLADTDRERALRR-MQQMAGHLGAFHPAPL 238
G + +GA+ + VK A+ +++ + + Q+ +P PL
Sbjct: 195 GQKP-SGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPL 237
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/81 (40%), Positives = 49/81 (60%)
Query: 395 GCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAI 454
G +F+Y+L + ++ L Q F PFGAV + KV D TN+ K FGFV+ N A AI
Sbjct: 282 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 341
Query: 455 QAMNGFQIGMKRLKVQLKRPK 475
++NG+++G + L+V K K
Sbjct: 342 ASLNGYRLGDRVLQVSFKTNK 362
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/82 (35%), Positives = 44/82 (53%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL + +LPQ E F G + S K+ D+ T QS +GFV++ +P A+ AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 457 MNGFQIGMKRLKVQLKRPKDAN 478
+NG ++ K +KV RP A+
Sbjct: 107 LNGLRLQTKTIKVSYARPSSAS 128
Score = 51.2 bits (121), Expect = 2e-06
Identities = 22/63 (34%), Positives = 38/63 (60%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL++ LP+ EL Q F +G ++++++ VD+ T S+ GF+ FD A+ AI+
Sbjct: 133 NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKG 192
Query: 457 MNG 459
+NG
Sbjct: 193 LNG 195
Score = 33.1 bits (74), Expect = 0.57
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 112 TLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRS-PD 170
T+ GM + + G G +FV L E + +LF PFG + V+R
Sbjct: 263 TIDGMTSLVGMNIPGHTGTGWC--IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNT 320
Query: 171 GTSKGCAFVKFGSQGEAQAAIRGLHGSR 198
KG FV + EA AI L+G R
Sbjct: 321 NKCKGFGFVTMTNYDEAAMAIASLNGYR 348
Score = 32.7 bits (73), Expect = 0.75
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDR 81
T D + G+N +P +FV + DE L LF FG + + V++D
Sbjct: 263 TIDGMTSLVGMN----IPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 318
Query: 82 LTGLHKGCAFLTYCARDSALKAQSALH 108
T KG F+T D A A ++L+
Sbjct: 319 NTNKCKGFGFVTMTNYDEAAMAIASLN 345
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 80.1 bits (196), Expect = 4e-15
Identities = 57/224 (25%), Positives = 109/224 (48%), Gaps = 10/224 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMK-----DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELT 76
T+++ G S N PM+ D L V +P+ + +++ + LF G I
Sbjct: 34 TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 93
Query: 77 VLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKL 136
+++D++TG G F+ Y A KA + L+ + + +P+++ R D L
Sbjct: 94 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR--DANL 151
Query: 137 FVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGSQGEAQAAIRGLH 195
+V L K ++++ +LF +G I +L G S+G F++F + EA+ AI+GL+
Sbjct: 152 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLN 211
Query: 196 GSRTMAGASSSLVVKLADTDRERALRR-MQQMAGHLGAFHPAPL 238
G + +GA+ + VK A+ +++ + + Q+ +P PL
Sbjct: 212 GQKP-SGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPL 254
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/81 (40%), Positives = 49/81 (60%)
Query: 395 GCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAI 454
G +F+Y+L + ++ L Q F PFGAV + KV D TN+ K FGFV+ N A AI
Sbjct: 299 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 358
Query: 455 QAMNGFQIGMKRLKVQLKRPK 475
++NG+++G + L+V K K
Sbjct: 359 ASLNGYRLGDRVLQVSFKTNK 379
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/82 (35%), Positives = 44/82 (53%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL + +LPQ E F G + S K+ D+ T QS +GFV++ +P A+ AI
Sbjct: 64 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 123
Query: 457 MNGFQIGMKRLKVQLKRPKDAN 478
+NG ++ K +KV RP A+
Sbjct: 124 LNGLRLQTKTIKVSYARPSSAS 145
Score = 51.2 bits (121), Expect = 2e-06
Identities = 22/63 (34%), Positives = 38/63 (60%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL++ LP+ EL Q F +G ++++++ VD+ T S+ GF+ FD A+ AI+
Sbjct: 150 NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKG 209
Query: 457 MNG 459
+NG
Sbjct: 210 LNG 212
Score = 33.1 bits (74), Expect = 0.57
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 112 TLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRS-PD 170
T+ GM + + G G +FV L E + +LF PFG + V+R
Sbjct: 280 TIDGMTSLVGMNIPGHTGTGWC--IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNT 337
Query: 171 GTSKGCAFVKFGSQGEAQAAIRGLHGSR 198
KG FV + EA AI L+G R
Sbjct: 338 NKCKGFGFVTMTNYDEAAMAIASLNGYR 365
Score = 32.7 bits (73), Expect = 0.75
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDR 81
T D + G+N +P +FV + DE L LF FG + + V++D
Sbjct: 280 TIDGMTSLVGMN----IPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 335
Query: 82 LTGLHKGCAFLTYCARDSALKAQSALH 108
T KG F+T D A A ++L+
Sbjct: 336 NTNKCKGFGFVTMTNYDEAAMAIASLN 362
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 80.1 bits (196), Expect = 4e-15
Identities = 57/224 (25%), Positives = 109/224 (48%), Gaps = 10/224 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMK-----DHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELT 76
T+++ G S N PM+ D L V +P+ + +++ + LF G I
Sbjct: 17 TSNTSNGPSSNNRNCPSPMQTGATTDDSKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCK 76
Query: 77 VLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKL 136
+++D++TG G F+ Y A KA + L+ + + +P+++ R D L
Sbjct: 77 LVRDKITGQSLGYGFVNYIDPKDAEKAINTLNGLRLQTKTIKVSYARPSSASIR--DANL 134
Query: 137 FVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGSQGEAQAAIRGLH 195
+V L K ++++ +LF +G I +L G S+G F++F + EA+ AI+GL+
Sbjct: 135 YVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGLN 194
Query: 196 GSRTMAGASSSLVVKLADTDRERALRR-MQQMAGHLGAFHPAPL 238
G + +GA+ + VK A+ +++ + + Q+ +P PL
Sbjct: 195 GQKP-SGATEPITVKFANNPSQKSSQALLSQLYQSPNRRYPGPL 237
Score = 60.8 bits (146), Expect = 3e-09
Identities = 33/81 (40%), Positives = 49/81 (60%)
Query: 395 GCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAI 454
G +F+Y+L + ++ L Q F PFGAV + KV D TN+ K FGFV+ N A AI
Sbjct: 282 GWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAI 341
Query: 455 QAMNGFQIGMKRLKVQLKRPK 475
++NG+++G + L+V K K
Sbjct: 342 ASLNGYRLGDRVLQVSFKTNK 362
Score = 58.5 bits (140), Expect = 1e-08
Identities = 29/82 (35%), Positives = 44/82 (53%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL + +LPQ E F G + S K+ D+ T QS +GFV++ +P A+ AI
Sbjct: 47 NLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 106
Query: 457 MNGFQIGMKRLKVQLKRPKDAN 478
+NG ++ K +KV RP A+
Sbjct: 107 LNGLRLQTKTIKVSYARPSSAS 128
Score = 51.2 bits (121), Expect = 2e-06
Identities = 22/63 (34%), Positives = 38/63 (60%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL++ LP+ EL Q F +G ++++++ VD+ T S+ GF+ FD A+ AI+
Sbjct: 133 NLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKG 192
Query: 457 MNG 459
+NG
Sbjct: 193 LNG 195
Score = 33.1 bits (74), Expect = 0.57
Identities = 27/88 (30%), Positives = 37/88 (42%), Gaps = 3/88 (3%)
Query: 112 TLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRS-PD 170
T+ GM + + G G +FV L E + +LF PFG + V+R
Sbjct: 263 TIDGMTSLVGMNIPGHTGTGWC--IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNT 320
Query: 171 GTSKGCAFVKFGSQGEAQAAIRGLHGSR 198
KG FV + EA AI L+G R
Sbjct: 321 NKCKGFGFVTMTNYDEAAMAIASLNGYR 348
Score = 32.7 bits (73), Expect = 0.75
Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 4/87 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDR 81
T D + G+N +P +FV + DE L LF FG + + V++D
Sbjct: 263 TIDGMTSLVGMN----IPGHTGTGWCIFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDF 318
Query: 82 LTGLHKGCAFLTYCARDSALKAQSALH 108
T KG F+T D A A ++L+
Sbjct: 319 NTNKCKGFGFVTMTNYDEAAMAIASLN 345
>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
Length = 424
Score = 80.1 bits (196), Expect = 4e-15
Identities = 99/373 (26%), Positives = 154/373 (41%), Gaps = 44/373 (11%)
Query: 35 GPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTY 94
GP + ++ DA ++VG + + E L LF + G + + KDR+TG H+G F+ +
Sbjct: 4 GP-ISERNQDAT-VYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEF 61
Query: 95 CARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGED--RKLFVGMLGKQQGEEDVRR 152
+ + A A+ + +PI+V A++ + D +F+G L + E+ +
Sbjct: 62 LSEED---ADYAIKIMNMIKLYGKPIRVNKASAHNKNLDVGANIFIGNLDPEIDEKLLYD 118
Query: 153 LFQPFGHI-EECTVLRSPD-GTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVK 210
F FG I + ++R PD G SKG AF+ F S + AAI ++G +
Sbjct: 119 TFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAAIEAMNGQYLCNRPITVSYAF 178
Query: 211 LADTDRERALRRMQQMAGHLGAFHPAPLPLGACGAYTTAILQHQAALLAAAQGPGLGPVA 270
D+ ER +++ L A + A HQ L A A P P
Sbjct: 179 KKDSKGERHGSAAERL-------------LAAQNPLSQADRPHQ--LFADAPPPPSAPNP 223
Query: 271 AVAAQMQHVAAFSLVAAPLLPAAAANSPPGSGPGTL-PGL-------PAPIGVNGFGPLT 322
V+ + S + P +P + PP PG L PG+ P P G G GP +
Sbjct: 224 VVS------SLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAAGHGPPS 277
Query: 323 PQT--NGQPGSDTLYNNGLSPYPAQSPGVADPLQQAYAGMHHYAAAYPSAYAPVSTAFPQ 380
T G PG + + P PG++ +Q A+ G H +P A P S P
Sbjct: 278 AGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQ-MQLAHHGPH--GLGHPHAGPPGSGGQP- 333
Query: 381 QPSALPQQQREGP 393
P P GP
Sbjct: 334 PPRPPPGMPHPGP 346
Score = 46.6 bits (109), Expect = 5e-05
Identities = 27/84 (32%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 395 GCNLFIYHLPQEFGDAELIQTFLPFGAVVSA-KVFVDRATNQSKCFGFVSFDNPTSAQTA 453
G N+FI +L E + L TF FG ++ K+ D T SK + F++F + ++ A
Sbjct: 99 GANIFIGNLDPEIDEKLLYDTFSAFGVILQTPKIMRDPDTGNSKGYAFINFASFDASDAA 158
Query: 454 IQAMNGFQIGMKRLKVQLKRPKDA 477
I+AMNG + + + V KD+
Sbjct: 159 IEAMNGQYLCNRPITVSYAFKKDS 182
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/79 (29%), Positives = 41/79 (51%)
Query: 391 EGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSA 450
E + +++ L ++ + L + FL G VV+ + DR T Q + +GFV F + A
Sbjct: 8 ERNQDATVYVGGLDEKVSEPLLWELFLQAGPVVNTHMPKDRVTGQHQGYGFVEFLSEEDA 67
Query: 451 QTAIQAMNGFQIGMKRLKV 469
AI+ MN ++ K ++V
Sbjct: 68 DYAIKIMNMIKLYGKPIRV 86
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 77.8 bits (190), Expect = 2e-14
Identities = 52/193 (26%), Positives = 97/193 (50%), Gaps = 5/193 (2%)
Query: 48 LFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSAL 107
L V +P+ + +++LK LF G I +++D++TG G F+ Y A KA + L
Sbjct: 41 LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
Query: 108 HEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVL- 166
+ + + +P+++ R D L+V L K ++++ +LF +G I +L
Sbjct: 101 NGLRLQTKTIKVSYARPSSASIR--DANLYVSGLPKTMTQKELEQLFSQYGRIITSRILV 158
Query: 167 RSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRR-MQQ 225
G S+G F++F + EA+ AI+GL+G + GA+ + VK A+ ++ + + Q
Sbjct: 159 DQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKP-PGATEPITVKFANNPSQKTNQAILSQ 217
Query: 226 MAGHLGAFHPAPL 238
+ +P PL
Sbjct: 218 LYQSPNRRYPGPL 230
Score = 72.8 bits (177), Expect = 7e-13
Identities = 92/368 (25%), Positives = 138/368 (37%), Gaps = 65/368 (17%)
Query: 129 GRGEDRK--LFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGSQG 185
G ED K L V L + +E+++ LF G IE C ++R G S G FV +
Sbjct: 32 GNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPK 91
Query: 186 EAQAAIRGLHGSR--------TMAGASSSLV----VKLADTDRERALRRMQQMAGHLGAF 233
+A+ AI L+G R + A SS+ + + ++ + + ++Q+ G
Sbjct: 92 DAEKAINTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRI 151
Query: 234 HPAPLPLGACGAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVAAFSLVAAPLLPAA 293
T+ IL Q ++ G F +
Sbjct: 152 ------------ITSRILVDQVTGISRGVG------------------FIRFDKRIEAEE 181
Query: 294 AANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYP------AQSP 347
A G P PG PI V F Q Q LY + YP AQ
Sbjct: 182 AIKGLNGQKP---PGATEPITVK-FANNPSQKTNQAILSQLYQSPNRRYPGPLAQQAQRF 237
Query: 348 GVADPLQQAYAGMHHYAAAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEF 407
+ + L AY + P P G +F+Y+L +
Sbjct: 238 RLDNLLNMAYGVKRFSPMTIDGMTSLAGINIPGHPGT----------GWCIFVYNLAPDA 287
Query: 408 GDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRL 467
++ L Q F PFGAV + KV D TN+ K FGFV+ N A AI ++NG+++G + L
Sbjct: 288 DESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGDRVL 347
Query: 468 KVQLKRPK 475
+V K K
Sbjct: 348 QVSFKTNK 355
Score = 60.1 bits (144), Expect = 4e-09
Identities = 30/82 (36%), Positives = 45/82 (54%)
Query: 397 NLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQA 456
NL + +LPQ EL F G + S K+ D+ T QS +GFV++ +P A+ AI
Sbjct: 40 NLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINT 99
Query: 457 MNGFQIGMKRLKVQLKRPKDAN 478
+NG ++ K +KV RP A+
Sbjct: 100 LNGLRLQTKTIKVSYARPSSAS 121
Score = 33.5 bits (75), Expect = 0.44
Identities = 24/87 (27%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Query: 22 TADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDR 81
T D ++G+N +P +FV + DE L +F FG + + V++D
Sbjct: 256 TIDGMTSLAGIN----IPGHPGTGWCIFVYNLAPDADESILWQMFGPFGAVTNVKVIRDF 311
Query: 82 LTGLHKGCAFLTYCARDSALKAQSALH 108
T KG F+T D A A ++L+
Sbjct: 312 NTNKCKGFGFVTMTNYDEAAMAIASLN 338
>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
[Homo sapiens]
Length = 535
Score = 73.9 bits (180), Expect = 3e-13
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 30/194 (15%)
Query: 7 GSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLF 66
G + GP P +S G+G ++FVG+IPR L E +L PLF
Sbjct: 42 GQRKYGGPPPDSVYSGVQPGIGT-----------------EVFVGKIPRDLYEDELVPLF 84
Query: 67 EEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAA 126
E+ G I++L ++ D L+G ++G AF+T+C +++A +A + PG + + + A
Sbjct: 85 EKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVA- 143
Query: 127 SEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTV----LRSPDGTSK--GCAFVK 180
+ +LFVG + K + +E++ F + E V PD K G F++
Sbjct: 144 ------NNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLE 197
Query: 181 FGSQGEAQAAIRGL 194
+ A A R L
Sbjct: 198 YEDHKSAAQARRRL 211
Score = 40.0 bits (92), Expect = 0.005
Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 30/209 (14%)
Query: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLH--------KGCAFLTYCARD 98
+LFVG IP+ ++++ EEF ++ LT + H +G FL Y
Sbjct: 146 RLFVGSIPKNKTKENI---LEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 202
Query: 99 SALKAQSALHEQKTLPGMNRPI-----QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRL 153
SA +A+ L K N V+ E + + LFV L EE + +
Sbjct: 203 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 262
Query: 154 FQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLAD 213
F FG +E L K AFV F +G A A+ ++G + + G +V+
Sbjct: 263 FSEFGKLERVKKL-------KDYAFVHFEDRGAAVKAMDEMNG-KEIEGEEIEIVL-AKP 313
Query: 214 TDRERALRRMQQMAGHLGA-----FHPAP 237
D++R R+ + A A +HP P
Sbjct: 314 PDKKRKERQAARQASRSTAYEDYYYHPPP 342
Score = 33.5 bits (75), Expect = 0.44
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 398 LFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAM 457
LF+ +L + L ++F FG + K D + FV F++ +A A+ M
Sbjct: 245 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 296
Query: 458 NGFQIGMKRLKVQLKRPKDANR 479
NG +I + +++ L +P D R
Sbjct: 297 NGKEIEGEEIEIVLAKPPDKKR 318
>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
[Homo sapiens]
Length = 636
Score = 73.9 bits (180), Expect = 3e-13
Identities = 54/194 (27%), Positives = 90/194 (46%), Gaps = 30/194 (15%)
Query: 7 GSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLF 66
G + GP P +S G+G ++FVG+IPR L E +L PLF
Sbjct: 143 GQRKYGGPPPDSVYSGVQPGIGT-----------------EVFVGKIPRDLYEDELVPLF 185
Query: 67 EEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAA 126
E+ G I++L ++ D L+G ++G AF+T+C +++A +A + PG + + + A
Sbjct: 186 EKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVA- 244
Query: 127 SEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTV----LRSPDGTSK--GCAFVK 180
+ +LFVG + K + +E++ F + E V PD K G F++
Sbjct: 245 ------NNRLFVGSIPKNKTKENILEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLE 298
Query: 181 FGSQGEAQAAIRGL 194
+ A A R L
Sbjct: 299 YEDHKSAAQARRRL 312
Score = 40.0 bits (92), Expect = 0.005
Identities = 54/209 (25%), Positives = 85/209 (40%), Gaps = 30/209 (14%)
Query: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLH--------KGCAFLTYCARD 98
+LFVG IP+ ++++ EEF ++ LT + H +G FL Y
Sbjct: 247 RLFVGSIPKNKTKENI---LEEFSKVTGLTEGLVDVILYHQPDDKKKNRGFCFLEYEDHK 303
Query: 99 SALKAQSALHEQKTLPGMNRPI-----QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRL 153
SA +A+ L K N V+ E + + LFV L EE + +
Sbjct: 304 SAAQARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKS 363
Query: 154 FQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLAD 213
F FG +E L K AFV F +G A A+ ++G + + G +V+
Sbjct: 364 FSEFGKLERVKKL-------KDYAFVHFEDRGAAVKAMDEMNG-KEIEGEEIEIVL-AKP 414
Query: 214 TDRERALRRMQQMAGHLGA-----FHPAP 237
D++R R+ + A A +HP P
Sbjct: 415 PDKKRKERQAARQASRSTAYEDYYYHPPP 443
Score = 33.5 bits (75), Expect = 0.44
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 398 LFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAM 457
LF+ +L + L ++F FG + K D + FV F++ +A A+ M
Sbjct: 346 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 397
Query: 458 NGFQIGMKRLKVQLKRPKDANR 479
NG +I + +++ L +P D R
Sbjct: 398 NGKEIEGEEIEIVLAKPPDKKR 419
>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
[Homo sapiens]
Length = 532
Score = 73.9 bits (180), Expect = 3e-13
Identities = 52/191 (27%), Positives = 90/191 (47%), Gaps = 27/191 (14%)
Query: 7 GSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLF 66
G + GP P +S G+G ++FVG+IPR L E +L PLF
Sbjct: 42 GQRKYGGPPPDSVYSGVQPGIGT-----------------EVFVGKIPRDLYEDELVPLF 84
Query: 67 EEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAA 126
E+ G I++L ++ D L+G ++G AF+T+C +++A +A + PG + + + A
Sbjct: 85 EKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVA- 143
Query: 127 SEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGH-IEECTVLRSPDGTSK--GCAFVKFGS 183
+ +LFVG + K + +E++ F + + + PD K G F+++
Sbjct: 144 ------NNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYED 197
Query: 184 QGEAQAAIRGL 194
A A R L
Sbjct: 198 HKSAAQARRRL 208
Score = 39.3 bits (90), Expect = 0.008
Identities = 52/206 (25%), Positives = 85/206 (41%), Gaps = 27/206 (13%)
Query: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYE-----LTVLKDRLTGLHKGCAFLTYCARDSAL 101
+LFVG IP+ ++++ EEF ++ E + + ++G FL Y SA
Sbjct: 146 RLFVGSIPKNKTKENI---LEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 202
Query: 102 KAQSALHEQKTLPGMNRPI-----QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQP 156
+A+ L K N V+ E + + LFV L EE + + F
Sbjct: 203 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 262
Query: 157 FGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDR 216
FG +E L K AFV F +G A A+ ++G + + G +V+ D+
Sbjct: 263 FGKLERVKKL-------KDYAFVHFEDRGAAVKAMDEMNG-KEIEGEEIEIVL-AKPPDK 313
Query: 217 ERALRRMQQMAGHLGA-----FHPAP 237
+R R+ + A A +HP P
Sbjct: 314 KRKERQAARQASRSTAYEDYYYHPPP 339
Score = 33.5 bits (75), Expect = 0.44
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 398 LFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAM 457
LF+ +L + L ++F FG + K D + FV F++ +A A+ M
Sbjct: 242 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 293
Query: 458 NGFQIGMKRLKVQLKRPKDANR 479
NG +I + +++ L +P D R
Sbjct: 294 NGKEIEGEEIEIVLAKPPDKKR 315
>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
[Homo sapiens]
Length = 633
Score = 73.9 bits (180), Expect = 3e-13
Identities = 52/191 (27%), Positives = 90/191 (47%), Gaps = 27/191 (14%)
Query: 7 GSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLF 66
G + GP P +S G+G ++FVG+IPR L E +L PLF
Sbjct: 143 GQRKYGGPPPDSVYSGVQPGIGT-----------------EVFVGKIPRDLYEDELVPLF 185
Query: 67 EEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAA 126
E+ G I++L ++ D L+G ++G AF+T+C +++A +A + PG + + + A
Sbjct: 186 EKAGPIWDLRLMMDPLSGQNRGYAFITFCGKEAAQEAVKLCDSYEIRPGKHLGVCISVA- 244
Query: 127 SEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGH-IEECTVLRSPDGTSK--GCAFVKFGS 183
+ +LFVG + K + +E++ F + + + PD K G F+++
Sbjct: 245 ------NNRLFVGSIPKNKTKENILEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYED 298
Query: 184 QGEAQAAIRGL 194
A A R L
Sbjct: 299 HKSAAQARRRL 309
Score = 39.3 bits (90), Expect = 0.008
Identities = 52/206 (25%), Positives = 85/206 (41%), Gaps = 27/206 (13%)
Query: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYE-----LTVLKDRLTGLHKGCAFLTYCARDSAL 101
+LFVG IP+ ++++ EEF ++ E + + ++G FL Y SA
Sbjct: 247 RLFVGSIPKNKTKENI---LEEFSKVTEGLVDVILYHQPDDKKKNRGFCFLEYEDHKSAA 303
Query: 102 KAQSALHEQKTLPGMNRPI-----QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQP 156
+A+ L K N V+ E + + LFV L EE + + F
Sbjct: 304 QARRRLMSGKVKVWGNVVTVEWADPVEEPDPEVMAKVKVLFVRNLATTVTEEILEKSFSE 363
Query: 157 FGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDR 216
FG +E L K AFV F +G A A+ ++G + + G +V+ D+
Sbjct: 364 FGKLERVKKL-------KDYAFVHFEDRGAAVKAMDEMNG-KEIEGEEIEIVL-AKPPDK 414
Query: 217 ERALRRMQQMAGHLGA-----FHPAP 237
+R R+ + A A +HP P
Sbjct: 415 KRKERQAARQASRSTAYEDYYYHPPP 440
Score = 33.5 bits (75), Expect = 0.44
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 8/82 (9%)
Query: 398 LFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAM 457
LF+ +L + L ++F FG + K D + FV F++ +A A+ M
Sbjct: 343 LFVRNLATTVTEEILEKSFSEFGKLERVKKLKD--------YAFVHFEDRGAAVKAMDEM 394
Query: 458 NGFQIGMKRLKVQLKRPKDANR 479
NG +I + +++ L +P D R
Sbjct: 395 NGKEIEGEEIEIVLAKPPDKKR 416
>gi|93277070 RNA binding motif protein 45 [Homo sapiens]
Length = 474
Score = 73.9 bits (180), Expect = 3e-13
Identities = 60/216 (27%), Positives = 97/216 (44%), Gaps = 13/216 (6%)
Query: 24 DSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLT 83
++G SG P V D I + E L+ F FG I ++ V++D+ T
Sbjct: 3 EAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDKHT 62
Query: 84 GLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDR--------K 135
KG AF+ + A +A +H Q P +PI+V A S G R +
Sbjct: 63 KESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTR 122
Query: 136 LFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSP-DGTSKGCAFVKFGSQGEAQAAIRGL 194
+FV M+ K EED+R F+ +G IE C+++++ G SKG +V++ +A AI
Sbjct: 123 IFV-MIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENC 181
Query: 195 HGS-RTMAGASSSLVVKLADTDRERALRRMQQMAGH 229
S R + + + ++ D +R Q+ GH
Sbjct: 182 DRSFRAILAEPKNKASESSEQDYYSNMR--QEALGH 215
Score = 37.0 bits (84), Expect = 0.040
Identities = 20/88 (22%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Query: 368 PSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKV 427
P+ P+ Q S+ + E E +F+ +P+ + + +L + F +G + +
Sbjct: 93 PNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVM-IPKSYTEEDLREKFKVYGDIEYCSI 151
Query: 428 FVDRATNQSKCFGFVSFDNPTSAQTAIQ 455
++ T +SK G+V + P+ A AI+
Sbjct: 152 IKNKVTGESKGLGYVRYLKPSQAAQAIE 179
Score = 33.1 bits (74), Expect = 0.57
Identities = 18/55 (32%), Positives = 29/55 (52%)
Query: 409 DAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIG 463
++ L + F PFG + V D+ T +SK FV F + A A++ M+G +G
Sbjct: 38 ESVLRERFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCLG 92
>gi|228008400 synaptotagmin binding, cytoplasmic RNA interacting
protein isoform 6 [Homo sapiens]
Length = 562
Score = 73.6 bits (179), Expect = 4e-13
Identities = 46/151 (30%), Positives = 80/151 (52%), Gaps = 10/151 (6%)
Query: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSA 106
++FVG+IPR L E +L PLFE+ G I++L ++ D LTGL++G AF+T+C +++A +A
Sbjct: 163 EIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPLTGLNRGYAFVTFCTKEAAQEAVKL 222
Query: 107 LHEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGH-IEECTV 165
+ + G + + + A + +LFVG + K + +E + F + + +
Sbjct: 223 YNNHEIRSGKHIGVCISVA-------NNRLFVGSIPKSKTKEQILEEFSKVTEGLTDVIL 275
Query: 166 LRSPDGTSK--GCAFVKFGSQGEAQAAIRGL 194
PD K G F+++ A A R L
Sbjct: 276 YHQPDDKKKNRGFCFLEYEDHKTAAQARRRL 306
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/90 (25%), Positives = 42/90 (46%), Gaps = 10/90 (11%)
Query: 373 PVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRA 432
P S QQPS G +F+ +P++ + EL+ F G + ++ +D
Sbjct: 149 PDSVYSGQQPSV----------GTEIFVGKIPRDLFEDELVPLFEKAGPIWDLRLMMDPL 198
Query: 433 TNQSKCFGFVSFDNPTSAQTAIQAMNGFQI 462
T ++ + FV+F +AQ A++ N +I
Sbjct: 199 TGLNRGYAFVTFCTKEAAQEAVKLYNNHEI 228
Score = 35.0 bits (79), Expect = 0.15
Identities = 45/191 (23%), Positives = 79/191 (41%), Gaps = 22/191 (11%)
Query: 47 KLFVGQIPRGLDEQDLKPLFEEFGRIYE-----LTVLKDRLTGLHKGCAFLTYCARDSAL 101
+LFVG IP+ ++ + EEF ++ E + + ++G FL Y +A
Sbjct: 244 RLFVGSIPKSKTKEQI---LEEFSKVTEGLTDVILYHQPDDKKKNRGFCFLEYEDHKTAA 300
Query: 102 KAQSALHEQKTLPGMNRPI-----QVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQP 156
+A+ L K N ++ E + + LFV L EE + + F
Sbjct: 301 QARRRLMSGKVKVWGNVGTVEWADPIEDPDPEVMAKVKVLFVRNLANTVTEEILEKAFSQ 360
Query: 157 FGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDR 216
FG +E L K AF+ F + A A+ ++G + + G + +V D+
Sbjct: 361 FGKLERVKKL-------KDYAFIHFDERDGAVKAMEEMNG-KDLEGENIEIVF-AKPPDQ 411
Query: 217 ERALRRMQQMA 227
+R R+ Q+ A
Sbjct: 412 KRKERKAQRQA 422
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 398 LFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAM 457
LF+ +L + L + F FG + K D + F+ FD A A++ M
Sbjct: 340 LFVRNLANTVTEEILEKAFSQFGKLERVKKLKD--------YAFIHFDERDGAVKAMEEM 391
Query: 458 NGFQIGMKRLKVQLKRPKDANR 479
NG + + +++ +P D R
Sbjct: 392 NGKDLEGENIEIVFAKPPDQKR 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,111,888
Number of Sequences: 37866
Number of extensions: 1185787
Number of successful extensions: 7946
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 231
Number of HSP's successfully gapped in prelim test: 418
Number of HSP's that attempted gapping in prelim test: 5649
Number of HSP's gapped (non-prelim): 2251
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.