Guide to the Human Genome
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Search of human proteins with 70780361

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70780361 ankyrin 1 isoform 7 [Homo sapiens]
         (109 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70780361 ankyrin 1 isoform 7 [Homo sapiens]                        221   7e-59
gi|70780366 ankyrin 1 isoform 5 [Homo sapiens]                        203   3e-53
gi|215598566 ankyrin 1 isoform 10 [Homo sapiens]                      203   3e-53
gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]                        69   6e-13
gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]                         69   6e-13
gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]                         64   3e-11
gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]                         64   3e-11
gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]                         64   3e-11
gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]                        39   0.001
gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]                         39   0.001
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]                         39   0.001
gi|146260268 Smith-Magenis syndrome chromosome region, candidate...    28   1.2  
gi|194018501 C-type lectin domain family 12, member B isoform 1 ...    28   1.2  
gi|194018499 C-type lectin domain family 12, member B isoform 2 ...    28   1.2  
gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens]             28   1.6  
gi|119120915 rhophilin 1 [Homo sapiens]                                28   2.1  
gi|239756382 PREDICTED: similar to KIAA1920 protein [Homo sapiens]     27   2.7  
gi|148746195 trichohyalin [Homo sapiens]                               27   4.6  
gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens]                26   7.9  
gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]              26   7.9  
gi|30794372 polybromo 1 isoform 1 [Homo sapiens]                       26   7.9  
gi|93102371 polybromo 1 isoform 2 [Homo sapiens]                       26   7.9  
gi|41281917 polybromo 1 isoform 4 [Homo sapiens]                       26   7.9  

>gi|70780361 ankyrin 1 isoform 7 [Homo sapiens]
          Length = 109

 Score =  221 bits (564), Expect = 7e-59
 Identities = 109/109 (100%), Positives = 109/109 (100%)

Query: 1   MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET 60
           MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
Sbjct: 1   MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET 60

Query: 61  ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKDHTSTPNP 109
           ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKDHTSTPNP
Sbjct: 61  ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKKDHTSTPNP 109


>gi|70780366 ankyrin 1 isoform 5 [Homo sapiens]
          Length = 155

 Score =  203 bits (516), Expect = 3e-53
 Identities = 101/101 (100%), Positives = 101/101 (100%)

Query: 1   MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET 60
           MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
Sbjct: 1   MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET 60

Query: 61  ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
           ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK
Sbjct: 61  ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101


>gi|215598566 ankyrin 1 isoform 10 [Homo sapiens]
          Length = 156

 Score =  203 bits (516), Expect = 3e-53
 Identities = 101/101 (100%), Positives = 101/101 (100%)

Query: 1   MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET 60
           MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET
Sbjct: 1   MWTFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEET 60

Query: 61  ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
           ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK
Sbjct: 61  ISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101


>gi|215598574 ankyrin 1 isoform 9 [Homo sapiens]
          Length = 1897

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 42/86 (48%), Positives = 50/86 (58%), Gaps = 29/86 (33%)

Query: 46   KELGESEGLSDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK---- 101
            ++ G+ E + + + T  T+VV+      GNEFQNIPGEQVTEEQFTDEQGNIVTKK    
Sbjct: 1819 RQQGQEEQVQEAKNTF-TQVVQ------GNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRK 1871

Query: 102  ------------------DHTSTPNP 109
                              DHTSTPNP
Sbjct: 1872 VVRQIDLSSADAAQEHEEDHTSTPNP 1897


>gi|70780353 ankyrin 1 isoform 4 [Homo sapiens]
          Length = 1856

 Score = 69.3 bits (168), Expect = 6e-13
 Identities = 42/86 (48%), Positives = 50/86 (58%), Gaps = 29/86 (33%)

Query: 46   KELGESEGLSDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK---- 101
            ++ G+ E + + + T  T+VV+      GNEFQNIPGEQVTEEQFTDEQGNIVTKK    
Sbjct: 1778 RQQGQEEQVQEAKNTF-TQVVQ------GNEFQNIPGEQVTEEQFTDEQGNIVTKKIIRK 1830

Query: 102  ------------------DHTSTPNP 109
                              DHTSTPNP
Sbjct: 1831 VVRQIDLSSADAAQEHEEDHTSTPNP 1856


>gi|70780359 ankyrin 1 isoform 1 [Homo sapiens]
          Length = 1881

 Score = 63.5 bits (153), Expect = 3e-11
 Identities = 34/56 (60%), Positives = 42/56 (75%), Gaps = 7/56 (12%)

Query: 46   KELGESEGLSDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
            ++ G+ E + + + T  T+VV+      GNEFQNIPGEQVTEEQFTDEQGNIVTKK
Sbjct: 1778 RQQGQEEQVQEAKNTF-TQVVQ------GNEFQNIPGEQVTEEQFTDEQGNIVTKK 1826


>gi|70780357 ankyrin 1 isoform 3 [Homo sapiens]
          Length = 1880

 Score = 63.5 bits (153), Expect = 3e-11
 Identities = 34/56 (60%), Positives = 42/56 (75%), Gaps = 7/56 (12%)

Query: 46   KELGESEGLSDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
            ++ G+ E + + + T  T+VV+      GNEFQNIPGEQVTEEQFTDEQGNIVTKK
Sbjct: 1778 RQQGQEEQVQEAKNTF-TQVVQ------GNEFQNIPGEQVTEEQFTDEQGNIVTKK 1826


>gi|70780355 ankyrin 1 isoform 2 [Homo sapiens]
          Length = 1719

 Score = 63.5 bits (153), Expect = 3e-11
 Identities = 34/56 (60%), Positives = 42/56 (75%), Gaps = 7/56 (12%)

Query: 46   KELGESEGLSDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
            ++ G+ E + + + T  T+VV+      GNEFQNIPGEQVTEEQFTDEQGNIVTKK
Sbjct: 1616 RQQGQEEQVQEAKNTF-TQVVQ------GNEFQNIPGEQVTEEQFTDEQGNIVTKK 1664


>gi|188595682 ankyrin 2 isoform 3 [Homo sapiens]
          Length = 1863

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 18/47 (38%), Positives = 27/47 (57%)

Query: 55   SDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
            +D++     R+     F KG++   IP E VTEE++ DE G+ V KK
Sbjct: 1758 ADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKK 1804


>gi|52426737 ankyrin 2 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 18/47 (38%), Positives = 27/47 (57%)

Query: 55   SDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
            +D++     R+     F KG++   IP E VTEE++ DE G+ V KK
Sbjct: 1767 ADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKK 1813


>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
          Length = 3957

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 18/47 (38%), Positives = 27/47 (57%)

Query: 55   SDDEETISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTKK 101
            +D++     R+     F KG++   IP E VTEE++ DE G+ V KK
Sbjct: 3852 ADNQPETCERLDEDAAFEKGDDMPEIPPETVTEEEYIDEHGHTVVKK 3898


>gi|146260268 Smith-Magenis syndrome chromosome region, candidate 8
           [Homo sapiens]
          Length = 937

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 18/71 (25%), Positives = 33/71 (46%), Gaps = 1/71 (1%)

Query: 19  LVSCQNVMHIVRGSLCFVL-KHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGNEF 77
           L    ++ H+ RG LC++L   I + L K+   +  L +D   +  R+V ++  +     
Sbjct: 335 LAQLSHIEHMFRGDLCYLLTSQIDRALLKQQHITNFLFEDFVEVDDRMVEKQESIPSKPS 394

Query: 78  QNIPGEQVTEE 88
           Q+ P     EE
Sbjct: 395 QDRPPSSSLEE 405


>gi|194018501 C-type lectin domain family 12, member B isoform 1
           [Homo sapiens]
          Length = 276

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 3/66 (4%)

Query: 3   TFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELD---KELGESEGLSDDEE 59
           T    LL+ LV L    +   N ++     L  + K I Q+ D   ++LG S  LS +EE
Sbjct: 48  TLCLMLLIGLVTLGMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEE 107

Query: 60  TISTRV 65
            + +++
Sbjct: 108 FLKSQI 113


>gi|194018499 C-type lectin domain family 12, member B isoform 2
           [Homo sapiens]
          Length = 232

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 3/66 (4%)

Query: 3   TFVTQLLVTLVLLSFFLVSCQNVMHIVRGSLCFVLKHIHQELD---KELGESEGLSDDEE 59
           T    LL+ LV L    +   N ++     L  + K I Q+ D   ++LG S  LS +EE
Sbjct: 48  TLCLMLLIGLVTLGMMFLQISNDINSDSEKLSQLQKTIQQQQDNLSQQLGNSNNLSMEEE 107

Query: 60  TISTRV 65
            + +++
Sbjct: 108 FLKSQI 113


>gi|19923669 sel-1 suppressor of lin-12-like [Homo sapiens]
          Length = 794

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 5/70 (7%)

Query: 45  DKELGESEGLSDDEE----TISTRVVRRRVFLKGNEFQNIPGEQVTEEQFTDEQGNIVTK 100
           D+ L     L+ DE     T + RVV  ++FL   E +     Q  E+    ++G  VT+
Sbjct: 30  DESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTE 89

Query: 101 K-DHTSTPNP 109
                 +PNP
Sbjct: 90  DISFLESPNP 99


>gi|119120915 rhophilin 1 [Homo sapiens]
          Length = 670

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 18/55 (32%), Positives = 24/55 (43%)

Query: 19 LVSCQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLK 73
          L  C ++  I  G L      IHQ++DKEL    G  +     S   VR  V L+
Sbjct: 19 LQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALE 73


>gi|239756382 PREDICTED: similar to KIAA1920 protein [Homo sapiens]
          Length = 483

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 3/63 (4%)

Query: 27  HIV--RGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRRRVFLKGNEFQNIPGEQ 84
           HI+   GSL  +L+H H+ L  E+ ++  L    E ++ +++     L   E ++ PGE 
Sbjct: 71  HIIFPHGSLMVILEHTHKPLGPEVLQAYDLDSTCEGLAFQLLGTPSGLP-VEHRDQPGEP 129

Query: 85  VTE 87
           VTE
Sbjct: 130 VTE 132


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 26.6 bits (57), Expect = 4.6
 Identities = 17/58 (29%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 42  QELDKELGESEGLSDDEETISTRVVRRR---VFLKGNEFQNIPGEQVTEEQFTDEQGN 96
           QE ++EL E E  S+ +E +  R  +RR   ++ +  E+Q     +  EEQ    +G+
Sbjct: 142 QEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGH 199


>gi|5803167 splicing factor 3a, subunit 3 [Homo sapiens]
          Length = 501

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 9/18 (50%), Positives = 13/18 (72%)

Query: 86  TEEQFTDEQGNIVTKKDH 103
           TEE++ D  GN+V KK +
Sbjct: 475 TEEEYEDSSGNVVNKKTY 492


>gi|154240671 HEAT repeat family member 7B2 [Homo sapiens]
          Length = 1585

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 10/31 (32%), Positives = 18/31 (58%)

Query: 35  FVLKHIHQELDKELGESEGLSDDEETISTRV 65
           F +K IH E+++  G  EGL  D+  +  ++
Sbjct: 958 FYIKGIHLEVERLQGLQEGLESDDVQVQIKI 988


>gi|30794372 polybromo 1 isoform 1 [Homo sapiens]
          Length = 1602

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 11/47 (23%), Positives = 24/47 (51%)

Query: 22  CQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRR 68
           C+N   ++  +L +  KH+H +++KE  E      +E+ +     +R
Sbjct: 848 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKR 894


>gi|93102371 polybromo 1 isoform 2 [Homo sapiens]
          Length = 1582

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 11/47 (23%), Positives = 24/47 (51%)

Query: 22  CQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRR 68
           C+N   ++  +L +  KH+H +++KE  E      +E+ +     +R
Sbjct: 880 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKR 926


>gi|41281917 polybromo 1 isoform 4 [Homo sapiens]
          Length = 1582

 Score = 25.8 bits (55), Expect = 7.9
 Identities = 11/47 (23%), Positives = 24/47 (51%)

Query: 22  CQNVMHIVRGSLCFVLKHIHQELDKELGESEGLSDDEETISTRVVRR 68
           C+N   ++  +L +  KH+H +++KE  E      +E+ +     +R
Sbjct: 880 CKNGEILLSPALSYTTKHLHNDVEKERKEKLPKEIEEDKLKREEEKR 926


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,118,878
Number of Sequences: 37866
Number of extensions: 164820
Number of successful extensions: 538
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 509
Number of HSP's gapped (non-prelim): 33
length of query: 109
length of database: 18,247,518
effective HSP length: 79
effective length of query: 30
effective length of database: 15,256,104
effective search space: 457683120
effective search space used: 457683120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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