Guide to the Human Genome
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Search of human proteins with 70608172

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70608172 tumor protein D52 isoform 1 [Homo sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70608172 tumor protein D52 isoform 1 [Homo sapiens]                436   e-123
gi|4827038 tumor protein D52 isoform 3 [Homo sapiens]                 339   1e-93
gi|70608174 tumor protein D52 isoform 2 [Homo sapiens]                326   1e-89
gi|4507641 tumor protein D52-like 1 isoform 1 [Homo sapiens]          191   3e-49
gi|51173744 tumor protein D52-like 1 isoform 2 [Homo sapiens]         177   8e-45
gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens]         171   5e-43
gi|40805870 tumor protein D52-like 2 isoform d [Homo sapiens]         161   4e-40
gi|40805860 tumor protein D52-like 2 isoform e [Homo sapiens]         159   2e-39
gi|40805866 tumor protein D52-like 2 isoform b [Homo sapiens]         158   4e-39
gi|40805868 tumor protein D52-like 2 isoform c [Homo sapiens]         149   1e-36
gi|40805864 tumor protein D52-like 2 isoform a [Homo sapiens]         146   2e-35
gi|51173748 tumor protein D52-like 1 isoform 4 [Homo sapiens]         144   5e-35
gi|51173746 tumor protein D52-like 1 isoform 3 [Homo sapiens]         144   5e-35
gi|49574214 protein kinase NYD-SP25 isoform 1 [Homo sapiens]          108   5e-24
gi|49574212 protein kinase NYD-SP25 isoform 2 [Homo sapiens]           99   3e-21
gi|49574216 protein kinase NYD-SP25 isoform 3 [Homo sapiens]           99   4e-21
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         41   7e-04
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         41   7e-04
gi|148762940 DVL-binding protein DAPLE [Homo sapiens]                  39   0.004
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H...    39   0.005
gi|205277396 dynactin 1 isoform 4 [Homo sapiens]                       37   0.010
gi|205277392 dynactin 1 isoform 3 [Homo sapiens]                       37   0.010
gi|13259508 dynactin 1 isoform 2 [Homo sapiens]                        37   0.010
gi|13259510 dynactin 1 isoform 1 [Homo sapiens]                        37   0.010
gi|116517292 cut-like 2 [Homo sapiens]                                 37   0.014
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr...    37   0.018
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr...    37   0.018
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]      36   0.023
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo...    36   0.030
gi|157837985 kazrin isoform E [Homo sapiens]                           36   0.030

>gi|70608172 tumor protein D52 isoform 1 [Homo sapiens]
          Length = 224

 Score =  436 bits (1121), Expect = e-123
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MDCREMDLYEDYQSPFDFDAGVNKSYLYLSPSGNSSPPGSPTLQKFGLLRTDPVPEEGED 60
           MDCREMDLYEDYQSPFDFDAGVNKSYLYLSPSGNSSPPGSPTLQKFGLLRTDPVPEEGED
Sbjct: 1   MDCREMDLYEDYQSPFDFDAGVNKSYLYLSPSGNSSPPGSPTLQKFGLLRTDPVPEEGED 60

Query: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120
           VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK
Sbjct: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120

Query: 121 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEK 180
           QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEK
Sbjct: 121 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEK 180

Query: 181 VENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL 224
           VENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL
Sbjct: 181 VENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL 224


>gi|4827038 tumor protein D52 isoform 3 [Homo sapiens]
          Length = 184

 Score =  339 bits (869), Expect = 1e-93
 Identities = 178/178 (100%), Positives = 178/178 (100%)

Query: 47  GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE 106
           GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE
Sbjct: 7   GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE 66

Query: 107 IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE 166
           IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE
Sbjct: 67  IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE 126

Query: 167 DVKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL 224
           DVKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL
Sbjct: 127 DVKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQESL 184


>gi|70608174 tumor protein D52 isoform 2 [Homo sapiens]
          Length = 207

 Score =  326 bits (835), Expect = 1e-89
 Identities = 178/201 (88%), Positives = 178/201 (88%), Gaps = 23/201 (11%)

Query: 47  GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE 106
           GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE
Sbjct: 7   GLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAE 66

Query: 107 IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE 166
           IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE
Sbjct: 67  IKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLE 126

Query: 167 DVK-----------------------NSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLN 203
           DVK                       NSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLN
Sbjct: 127 DVKLQAFSHSFSIRSIQHSISMPAMRNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLN 186

Query: 204 SAANASATTTEPLPEKTQESL 224
           SAANASATTTEPLPEKTQESL
Sbjct: 187 SAANASATTTEPLPEKTQESL 207


>gi|4507641 tumor protein D52-like 1 isoform 1 [Homo sapiens]
          Length = 204

 Score =  191 bits (486), Expect = 3e-49
 Identities = 105/196 (53%), Positives = 136/196 (69%), Gaps = 17/196 (8%)

Query: 44  QKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKH 103
           Q  GLL T+P+    ED  A+   +  LSEEE+EEL+ EL ++E+EI TL QVL+AKE+H
Sbjct: 4   QAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERH 63

Query: 104 LAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITK 163
           L EIK+KLG+N + ELKQN +K W D+  T+AYKKT ETLS AGQKA+AAFS+VG+ I+K
Sbjct: 64  LVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISK 123

Query: 164 KLED-------------VKNSPTFKSFEEKVE----NLKSKVGGTKPAGGDFGEVLNSAA 206
           K  D             ++NSPTFKSFEE+VE    +LK+KVGGT P GG F EVL+S A
Sbjct: 124 KFGDMSYSIRHSISMPAMRNSPTFKSFEERVETTVTSLKTKVGGTNPNGGSFEEVLSSTA 183

Query: 207 NASATTTEPLPEKTQE 222
           +ASA +      +T+E
Sbjct: 184 HASAQSLAGGSRRTKE 199


>gi|51173744 tumor protein D52-like 1 isoform 2 [Homo sapiens]
          Length = 175

 Score =  177 bits (448), Expect = 8e-45
 Identities = 96/169 (56%), Positives = 123/169 (72%), Gaps = 17/169 (10%)

Query: 71  LSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDV 130
           LSEEE+EEL+ EL ++E+EI TL QVL+AKE+HL EIK+KLG+N + ELKQN +K W D+
Sbjct: 2   LSEEEKEELKAELVQLEDEITTLRQVLSAKERHLVEIKQKLGMNLMNELKQNFSKSWHDM 61

Query: 131 TATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLED-------------VKNSPTFKSF 177
             T+AYKKT ETLS AGQKA+AAFS+VG+ I+KK  D             ++NSPTFKSF
Sbjct: 62  QTTTAYKKTHETLSHAGQKATAAFSNVGTAISKKFGDMSYSIRHSISMPAMRNSPTFKSF 121

Query: 178 EEKVE----NLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLPEKTQE 222
           EE+VE    +LK+KVGGT P GG F EVL+S A+ASA +      +T+E
Sbjct: 122 EERVETTVTSLKTKVGGTNPNGGSFEEVLSSTAHASAQSLAGGSRRTKE 170


>gi|40805862 tumor protein D52-like 2 isoform f [Homo sapiens]
          Length = 186

 Score =  171 bits (433), Expect = 5e-43
 Identities = 90/157 (57%), Positives = 116/157 (73%), Gaps = 2/157 (1%)

Query: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120
           VAA   A E L+E E+EELR EL KVEEEI TL QVLAAKE+H  E+KR+LG+++L ELK
Sbjct: 31  VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90

Query: 121 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEK 180
           QN+++ W DV  +SAYKKT ETLSQAGQK SAA S+VGS I++KL D++NS TFKSFE++
Sbjct: 91  QNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMRNSATFKSFEDR 150

Query: 181 VENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLP 217
           V  +KSKV G +  G D   + +SA +     ++P P
Sbjct: 151 VGTIKSKVVGDRENGSD--NLPSSAGSGDKPLSDPAP 185


>gi|40805870 tumor protein D52-like 2 isoform d [Homo sapiens]
          Length = 200

 Score =  161 bits (408), Expect = 4e-40
 Identities = 90/171 (52%), Positives = 116/171 (67%), Gaps = 16/171 (9%)

Query: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120
           VAA   A E L+E E+EELR EL KVEEEI TL QVLAAKE+H  E+KR+LG+++L ELK
Sbjct: 31  VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90

Query: 121 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLED------------- 167
           QN+++ W DV  +SAYKKT ETLSQAGQK SAA S+VGS I++KL D             
Sbjct: 91  QNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMSSYSIRHSISMP 150

Query: 168 -VKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLP 217
            ++NS TFKSFE++V  +KSKV G +  G D   + +SA +     ++P P
Sbjct: 151 AMRNSATFKSFEDRVGTIKSKVVGDRENGSD--NLPSSAGSGDKPLSDPAP 199


>gi|40805860 tumor protein D52-like 2 isoform e [Homo sapiens]
          Length = 206

 Score =  159 bits (402), Expect = 2e-39
 Identities = 90/177 (50%), Positives = 116/177 (65%), Gaps = 22/177 (12%)

Query: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120
           VAA   A E L+E E+EELR EL KVEEEI TL QVLAAKE+H  E+KR+LG+++L ELK
Sbjct: 31  VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90

Query: 121 QNIAKGWQDVTATSA--------------------YKKTSETLSQAGQKASAAFSSVGSV 160
           QN+++ W DV  +SA                    YKKT ETLSQAGQK SAA S+VGS 
Sbjct: 91  QNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSA 150

Query: 161 ITKKLEDVKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLP 217
           I++KL D++NS TFKSFE++V  +KSKV G +  G D   + +SA +     ++P P
Sbjct: 151 ISRKLGDMRNSATFKSFEDRVGTIKSKVVGDRENGSD--NLPSSAGSGDKPLSDPAP 205


>gi|40805866 tumor protein D52-like 2 isoform b [Homo sapiens]
          Length = 209

 Score =  158 bits (399), Expect = 4e-39
 Identities = 90/180 (50%), Positives = 116/180 (64%), Gaps = 25/180 (13%)

Query: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120
           VAA   A E L+E E+EELR EL KVEEEI TL QVLAAKE+H  E+KR+LG+++L ELK
Sbjct: 31  VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90

Query: 121 QNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLED------------- 167
           QN+++ W DV  +SAYKKT ETLSQAGQK SAA S+VGS I++KL D             
Sbjct: 91  QNLSRSWHDVQVSSAYKKTQETLSQAGQKTSAALSTVGSAISRKLGDMRAHPFSHSFSSY 150

Query: 168 ----------VKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAANASATTTEPLP 217
                     ++NS TFKSFE++V  +KSKV G +  G D   + +SA +     ++P P
Sbjct: 151 SIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGDRENGSD--NLPSSAGSGDKPLSDPAP 208


>gi|40805868 tumor protein D52-like 2 isoform c [Homo sapiens]
          Length = 220

 Score =  149 bits (377), Expect = 1e-36
 Identities = 90/191 (47%), Positives = 116/191 (60%), Gaps = 36/191 (18%)

Query: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120
           VAA   A E L+E E+EELR EL KVEEEI TL QVLAAKE+H  E+KR+LG+++L ELK
Sbjct: 31  VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90

Query: 121 QNIAKGWQDVTATSA--------------------YKKTSETLSQAGQKASAAFSSVGSV 160
           QN+++ W DV  +SA                    YKKT ETLSQAGQK SAA S+VGS 
Sbjct: 91  QNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSA 150

Query: 161 ITKKLED--------------VKNSPTFKSFEEKVENLKSKVGGTKPAGGDFGEVLNSAA 206
           I++KL D              ++NS TFKSFE++V  +KSKV G +  G D   + +SA 
Sbjct: 151 ISRKLGDMSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGDRENGSD--NLPSSAG 208

Query: 207 NASATTTEPLP 217
           +     ++P P
Sbjct: 209 SGDKPLSDPAP 219


>gi|40805864 tumor protein D52-like 2 isoform a [Homo sapiens]
          Length = 229

 Score =  146 bits (368), Expect = 2e-35
 Identities = 90/200 (45%), Positives = 116/200 (58%), Gaps = 45/200 (22%)

Query: 61  VAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELK 120
           VAA   A E L+E E+EELR EL KVEEEI TL QVLAAKE+H  E+KR+LG+++L ELK
Sbjct: 31  VAARTPAVEGLTEAEEEELRAELTKVEEEIVTLRQVLAAKERHCGELKRRLGLSTLGELK 90

Query: 121 QNIAKGWQDVTATSA--------------------YKKTSETLSQAGQKASAAFSSVGSV 160
           QN+++ W DV  +SA                    YKKT ETLSQAGQK SAA S+VGS 
Sbjct: 91  QNLSRSWHDVQVSSAYVKTSEKLGEWNEKVTQSDLYKKTQETLSQAGQKTSAALSTVGSA 150

Query: 161 ITKKLED-----------------------VKNSPTFKSFEEKVENLKSKVGGTKPAGGD 197
           I++KL D                       ++NS TFKSFE++V  +KSKV G +  G D
Sbjct: 151 ISRKLGDMRAHPFSHSFSSYSIRHSISMPAMRNSATFKSFEDRVGTIKSKVVGDRENGSD 210

Query: 198 FGEVLNSAANASATTTEPLP 217
              + +SA +     ++P P
Sbjct: 211 --NLPSSAGSGDKPLSDPAP 228


>gi|51173748 tumor protein D52-like 1 isoform 4 [Homo sapiens]
          Length = 131

 Score =  144 bits (364), Expect = 5e-35
 Identities = 72/126 (57%), Positives = 95/126 (75%)

Query: 44  QKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKH 103
           Q  GLL T+P+    ED  A+   +  LSEEE+EEL+ EL ++E+EI TL QVL+AKE+H
Sbjct: 4   QAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERH 63

Query: 104 LAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITK 163
           L EIK+KLG+N + ELKQN +K W D+  T+AYKKT ETLS AGQKA+AAFS+VG+ I+K
Sbjct: 64  LVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISK 123

Query: 164 KLEDVK 169
           K  D++
Sbjct: 124 KFGDMR 129


>gi|51173746 tumor protein D52-like 1 isoform 3 [Homo sapiens]
          Length = 144

 Score =  144 bits (364), Expect = 5e-35
 Identities = 73/128 (57%), Positives = 95/128 (74%)

Query: 44  QKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKH 103
           Q  GLL T+P+    ED  A+   +  LSEEE+EEL+ EL ++E+EI TL QVL+AKE+H
Sbjct: 4   QAQGLLETEPLQGTDEDAVASADFSSMLSEEEKEELKAELVQLEDEITTLRQVLSAKERH 63

Query: 104 LAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITK 163
           L EIK+KLG+N + ELKQN +K W D+  T+AYKKT ETLS AGQKA+AAFS+VG+ I+K
Sbjct: 64  LVEIKQKLGMNLMNELKQNFSKSWHDMQTTTAYKKTHETLSHAGQKATAAFSNVGTAISK 123

Query: 164 KLEDVKNS 171
           K  D+  S
Sbjct: 124 KFGDMSYS 131


>gi|49574214 protein kinase NYD-SP25 isoform 1 [Homo sapiens]
          Length = 140

 Score =  108 bits (269), Expect = 5e-24
 Identities = 61/129 (47%), Positives = 82/129 (63%), Gaps = 9/129 (6%)

Query: 66  SATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAK 125
           S  E L+E EQ EL+ +L K+E EI TL  VLAAKE+   E+KRKLG+ +L  L+QN++K
Sbjct: 19  SELEDLTEPEQRELKTKLTKLEAEIVTLRHVLAAKERRCGELKRKLGLTALVGLRQNLSK 78

Query: 126 GWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLK 185
            W DV  ++ Y K         QK SAA S++G++I +KL  VK S T +SFE  +  +K
Sbjct: 79  SWLDVQVSNTYVK---------QKTSAALSTMGTLICRKLGGVKKSATLRSFEGLMGTIK 129

Query: 186 SKVGGTKPA 194
           SKV G K A
Sbjct: 130 SKVSGGKRA 138


>gi|49574212 protein kinase NYD-SP25 isoform 2 [Homo sapiens]
          Length = 136

 Score = 99.0 bits (245), Expect = 3e-21
 Identities = 55/118 (46%), Positives = 75/118 (63%), Gaps = 9/118 (7%)

Query: 66  SATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAK 125
           S  E L+E EQ EL+ +L K+E EI TL  VLAAKE+   E+KRKLG+ +L  L+QN++K
Sbjct: 19  SELEDLTEPEQRELKTKLTKLEAEIVTLRHVLAAKERRCGELKRKLGLTALVGLRQNLSK 78

Query: 126 GWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVEN 183
            W DV  ++ Y K         QK SAA S++G++I +KL  VK S T +SFE  + N
Sbjct: 79  SWLDVQVSNTYVK---------QKTSAALSTMGTLICRKLGGVKKSATLRSFEGLIFN 127


>gi|49574216 protein kinase NYD-SP25 isoform 3 [Homo sapiens]
          Length = 132

 Score = 98.6 bits (244), Expect = 4e-21
 Identities = 55/123 (44%), Positives = 77/123 (62%), Gaps = 9/123 (7%)

Query: 66  SATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAK 125
           S  E L+E EQ EL+ +L K+E EI TL  VLAAKE+   E+KRKLG+ +L  L+QN++K
Sbjct: 19  SELEDLTEPEQRELKTKLTKLEAEIVTLRHVLAAKERRCGELKRKLGLTALVGLRQNLSK 78

Query: 126 GWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLK 185
            W DV  ++ Y K         QK SAA S++G++I +KL  VK S T +SFE   +   
Sbjct: 79  SWLDVQVSNTYVK---------QKTSAALSTMGTLICRKLGGVKKSATLRSFEGNPKGEG 129

Query: 186 SKV 188
           S++
Sbjct: 130 SRI 132


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 12/154 (7%)

Query: 35   SSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLS 94
            SS P    +Q    LR D   E G D++A       L E +  E+   L   +E+++   
Sbjct: 2578 SSEPERTNIQNLNQLRED---ELGSDISALTLRISEL-ESQVVEMHTSLILEKEQVEIAE 2633

Query: 95   QVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAF 154
            + +  KEK L E+++ L  N  ++ ++   +  QDV       KT+  L  + ++ S  F
Sbjct: 2634 KNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVL----KTTTELFHSNEE-SGFF 2688

Query: 155  SSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
            + + ++   + E V       S++EK E L+ ++
Sbjct: 2689 NELEAL---RAESVATKAELASYKEKAEKLQEEL 2719



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 20/125 (16%)

Query: 73   EEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTA 132
            EE+ E+ R EL    EE+Q L   L        EI++K     LQEL+Q       D+  
Sbjct: 2209 EEQLEQFREELENKNEEVQQLHMQL--------EIQKKESTTRLQELEQENKLFKDDMEK 2260

Query: 133  TSAYKKTSETLS------------QAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEK 180
                 K S+ +S            Q  Q+       +   +TK  + +K +   K  EEK
Sbjct: 2261 LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEK 2320

Query: 181  VENLK 185
             E ++
Sbjct: 2321 NELIR 2325



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 8/118 (6%)

Query: 73  EEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTA 132
           + + E+L  EL+   E+IQ   Q +A +E  L E  + L  +++++LK  I    +    
Sbjct: 527 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSL--STVEDLKAEIVSASESRKE 584

Query: 133 TSAYKKTSET-----LSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLK 185
                +   T     L    ++ +A    +      +LE ++    F S EE++  LK
Sbjct: 585 LELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLF-SHEEELSKLK 641



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 12/40 (30%), Positives = 29/40 (72%), Gaps = 2/40 (5%)

Query: 71   LSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRK 110
            L+EE+ E++R+EL +  +E Q  +++L  ++ H+ +++R+
Sbjct: 1582 LNEEQLEDMRQELVRQYQEHQQATELL--RQAHMRQMERQ 1619


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 41.2 bits (95), Expect = 7e-04
 Identities = 38/154 (24%), Positives = 71/154 (46%), Gaps = 12/154 (7%)

Query: 35   SSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLS 94
            SS P    +Q    LR D   E G D++A       L E +  E+   L   +E+++   
Sbjct: 2570 SSEPERTNIQNLNQLRED---ELGSDISALTLRISEL-ESQVVEMHTSLILEKEQVEIAE 2625

Query: 95   QVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAF 154
            + +  KEK L E+++ L  N  ++ ++   +  QDV       KT+  L  + ++ S  F
Sbjct: 2626 KNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVL----KTTTELFHSNEE-SGFF 2680

Query: 155  SSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
            + + ++   + E V       S++EK E L+ ++
Sbjct: 2681 NELEAL---RAESVATKAELASYKEKAEKLQEEL 2711



 Score = 35.4 bits (80), Expect = 0.040
 Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 20/125 (16%)

Query: 73   EEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTA 132
            EE+ E+ R EL    EE+Q L   L        EI++K     LQEL+Q       D+  
Sbjct: 2201 EEQLEQFREELENKNEEVQQLHMQL--------EIQKKESTTRLQELEQENKLFKDDMEK 2252

Query: 133  TSAYKKTSETLS------------QAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEK 180
                 K S+ +S            Q  Q+       +   +TK  + +K +   K  EEK
Sbjct: 2253 LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEK 2312

Query: 181  VENLK 185
             E ++
Sbjct: 2313 NELIR 2317



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 27/118 (22%), Positives = 51/118 (43%), Gaps = 8/118 (6%)

Query: 73  EEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTA 132
           + + E+L  EL+   E+IQ   Q +A +E  L E  + L  +++++LK  I    +    
Sbjct: 527 QRQLEDLVEELSFSREQIQRARQTIAEQESKLNEAHKSL--STVEDLKAEIVSASESRKE 584

Query: 133 TSAYKKTSET-----LSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLK 185
                +   T     L    ++ +A    +      +LE ++    F S EE++  LK
Sbjct: 585 LELKHEAEVTNYKIKLEMLEKEKNAVLDRMAESQEAELERLRTQLLF-SHEEELSKLK 641



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 12/40 (30%), Positives = 29/40 (72%), Gaps = 2/40 (5%)

Query: 71   LSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRK 110
            L+EE+ E++R+EL +  +E Q  +++L  ++ H+ +++R+
Sbjct: 1582 LNEEQLEDMRQELVRQYQEHQQATELL--RQAHMRQMERQ 1619


>gi|148762940 DVL-binding protein DAPLE [Homo sapiens]
          Length = 2028

 Score = 38.9 bits (89), Expect = 0.004
 Identities = 24/99 (24%), Positives = 49/99 (49%), Gaps = 2/99 (2%)

Query: 53  PVPEEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLG 112
           P P +     +T S T +LS E+++ L  ELA  +  ++ + Q L  K + L + + ++ 
Sbjct: 226 PSPIKSSSADSTPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEDKTEQLVDTRHEVD 285

Query: 113 --INSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 149
             +  LQ++KQ   +   D  +  AY+   ++L +   +
Sbjct: 286 QLVLELQKVKQENIQLAADARSARAYRDELDSLREKANR 324


>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
            sapiens]
          Length = 1940

 Score = 38.5 bits (88), Expect = 0.005
 Identities = 36/136 (26%), Positives = 67/136 (49%), Gaps = 6/136 (4%)

Query: 56   EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 115
            E+ E++ A ++A +   E+E  EL++++  +E    TL++V   KEKH  E K K     
Sbjct: 928  EDEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLAKV--EKEKHATENKVKNLTEE 982

Query: 116  LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNS-PTF 174
            L  L + IAK  ++  A     + +    QA +    + +   S + +++ED+++S    
Sbjct: 983  LSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQE 1042

Query: 175  KSFEEKVENLKSKVGG 190
            K     +E  K K+ G
Sbjct: 1043 KKLRVDLERNKRKLEG 1058



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 24/103 (23%), Positives = 51/103 (49%), Gaps = 11/103 (10%)

Query: 56   EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAA--------KEKHLAEI 107
            EE E + + +S ++    ++ EEL+R+L +  +    L+  L +        +E++  E 
Sbjct: 1293 EEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQ 1352

Query: 108  KRKLGI-NSLQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 149
            + K  +  +L +    +A+ W+    T A ++T E L +A +K
Sbjct: 1353 EGKAELQRALSKANSEVAQ-WRTKYETDAIQRTEE-LEEAKKK 1393


>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
          Length = 1139

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 16/171 (9%)

Query: 32  SGNSSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSE-----------EEQEELR 80
           S +  P GS +  +  L  ++P       +AA I  T  L+            +E+E LR
Sbjct: 30  SSSLGPSGSASAGE--LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLR 87

Query: 81  RELAKVEEEIQTLSQVLAAKEKHLAEI-KRKLGINSLQELKQNIAKGWQDV--TATSAYK 137
            ++  +EE+++TL    A  +  L E+ K K+ +  +QE K  + +   D+      A K
Sbjct: 88  AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 147

Query: 138 KTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
           +  E L    +       +  ++    L+        +S +++VE LK +V
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 198



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 17/62 (27%), Positives = 30/62 (48%)

Query: 59  EDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQE 118
           +D    I   +T  EE Q  LR++  + EE +  L   +   E   AE+K++L   S + 
Sbjct: 851 KDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRT 910

Query: 119 LK 120
           ++
Sbjct: 911 IE 912


>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
          Length = 1253

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 16/171 (9%)

Query: 32  SGNSSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSE-----------EEQEELR 80
           S +  P GS +  +  L  ++P       +AA I  T  L+            +E+E LR
Sbjct: 144 SSSLGPSGSASAGE--LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLR 201

Query: 81  RELAKVEEEIQTLSQVLAAKEKHLAEI-KRKLGINSLQELKQNIAKGWQDV--TATSAYK 137
            ++  +EE+++TL    A  +  L E+ K K+ +  +QE K  + +   D+      A K
Sbjct: 202 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 261

Query: 138 KTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
           +  E L    +       +  ++    L+        +S +++VE LK +V
Sbjct: 262 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 312



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 17/62 (27%), Positives = 30/62 (48%)

Query: 59   EDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQE 118
            +D    I   +T  EE Q  LR++  + EE +  L   +   E   AE+K++L   S + 
Sbjct: 965  KDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRT 1024

Query: 119  LK 120
            ++
Sbjct: 1025 IE 1026


>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
          Length = 1144

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 16/171 (9%)

Query: 32  SGNSSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSE-----------EEQEELR 80
           S +  P GS +  +  L  ++P       +AA I  T  L+            +E+E LR
Sbjct: 30  SSSLGPSGSASAGE--LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLR 87

Query: 81  RELAKVEEEIQTLSQVLAAKEKHLAEI-KRKLGINSLQELKQNIAKGWQDV--TATSAYK 137
            ++  +EE+++TL    A  +  L E+ K K+ +  +QE K  + +   D+      A K
Sbjct: 88  AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 147

Query: 138 KTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
           +  E L    +       +  ++    L+        +S +++VE LK +V
Sbjct: 148 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 198



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 17/62 (27%), Positives = 30/62 (48%)

Query: 59  EDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQE 118
           +D    I   +T  EE Q  LR++  + EE +  L   +   E   AE+K++L   S + 
Sbjct: 851 KDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRT 910

Query: 119 LK 120
           ++
Sbjct: 911 IE 912


>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
          Length = 1278

 Score = 37.4 bits (85), Expect = 0.010
 Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 16/171 (9%)

Query: 32  SGNSSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSE-----------EEQEELR 80
           S +  P GS +  +  L  ++P       +AA I  T  L+            +E+E LR
Sbjct: 164 SSSLGPSGSASAGE--LSSSEPSTPAQTPLAAPIIPTPVLTSPGAVPPLPSPSKEEEGLR 221

Query: 81  RELAKVEEEIQTLSQVLAAKEKHLAEI-KRKLGINSLQELKQNIAKGWQDV--TATSAYK 137
            ++  +EE+++TL    A  +  L E+ K K+ +  +QE K  + +   D+      A K
Sbjct: 222 AQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARK 281

Query: 138 KTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
           +  E L    +       +  ++    L+        +S +++VE LK +V
Sbjct: 282 EAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERV 332



 Score = 28.5 bits (62), Expect = 4.9
 Identities = 17/62 (27%), Positives = 30/62 (48%)

Query: 59   EDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQE 118
            +D    I   +T  EE Q  LR++  + EE +  L   +   E   AE+K++L   S + 
Sbjct: 985  KDADERIEKVQTRLEETQALLRKKEKEFEETMDALQADIDQLEAEKAELKQRLNSQSKRT 1044

Query: 119  LK 120
            ++
Sbjct: 1045 IE 1046


>gi|116517292 cut-like 2 [Homo sapiens]
          Length = 1486

 Score = 37.0 bits (84), Expect = 0.014
 Identities = 24/104 (23%), Positives = 50/104 (48%), Gaps = 6/104 (5%)

Query: 79  LRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINSLQELKQNIAKGWQDVTATSAYKK 138
           L++EL  V  E+    +      KHL E++R+   N  +E+++ +A          +++ 
Sbjct: 20  LQKELNSVASELSARQEESEHSHKHLIELRREFKKNVPEEIREMVA------PVLKSFQA 73

Query: 139 TSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVE 182
               LS+  Q+A AAF SV   + +  + V      +S +++++
Sbjct: 74  EVVALSKRSQEAEAAFLSVYKQLIEAPDPVPVFEAARSLDDRLQ 117



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 24/85 (28%), Positives = 36/85 (42%), Gaps = 14/85 (16%)

Query: 40  SPTLQKFGLLRTDPVPEEGE---DVAATISATETLSEEEQEELRRELAKV---------- 86
           SP  Q+ G     P   EG     +      TETL +  + E ++ L +V          
Sbjct: 143 SPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQITLAARLGE 202

Query: 87  -EEEIQTLSQVLAAKEKHLAEIKRK 110
            EE+I+ L   L A +  L E++RK
Sbjct: 203 AEEKIKVLHSALKATQAELLELRRK 227


>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 2 [Homo sapiens]
          Length = 1403

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 38/176 (21%), Positives = 72/176 (40%), Gaps = 19/176 (10%)

Query: 22   VNKSYLYLSPSGNSSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRR 81
            V K +  L    NSS P +  LQ         + E  E     I A+    EEE +    
Sbjct: 1136 VTKLHQLLENQKNSSVPLAEHLQ---------IKEAFEKEVGIIKASLREKEEESQNKME 1186

Query: 82   ELAKVEEEIQTLSQVLAAKE-KHLAEIKR--------KLGINSLQELKQNIAKGWQDVTA 132
            E++K++ E+Q   Q L   E + + ++ +        +  I+SL E   N+ + +++V  
Sbjct: 1187 EVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCE 1246

Query: 133  TSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
               + K  E +S   +K    FS    +  +K    K+  T    + +++    ++
Sbjct: 1247 EVLHAKKKE-ISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQI 1301



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 12/114 (10%)

Query: 85  KVEEEIQTLSQVLAAKEKHLAEIKRKLG-----INSLQELKQNIAKGWQD-VTATSAYKK 138
           K E+EI  L   +   +K L+E+K+K G     I++L     N+ K   +       +++
Sbjct: 795 KHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEE 854

Query: 139 TSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKVGGTK 192
              TL+    K +     V     KK ED+     F   ++K E LK  +  T+
Sbjct: 855 VKMTLNDTLAKTNRELLDV----KKKFEDINQE--FVKIKDKNEILKRNLENTQ 902


>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
            repeats isoform 1 [Homo sapiens]
          Length = 1416

 Score = 36.6 bits (83), Expect = 0.018
 Identities = 38/176 (21%), Positives = 72/176 (40%), Gaps = 19/176 (10%)

Query: 22   VNKSYLYLSPSGNSSPPGSPTLQKFGLLRTDPVPEEGEDVAATISATETLSEEEQEELRR 81
            V K +  L    NSS P +  LQ         + E  E     I A+    EEE +    
Sbjct: 1149 VTKLHQLLENQKNSSVPLAEHLQ---------IKEAFEKEVGIIKASLREKEEESQNKME 1199

Query: 82   ELAKVEEEIQTLSQVLAAKE-KHLAEIKR--------KLGINSLQELKQNIAKGWQDVTA 132
            E++K++ E+Q   Q L   E + + ++ +        +  I+SL E   N+ + +++V  
Sbjct: 1200 EVSKLQSEVQNTKQALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCE 1259

Query: 133  TSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKV 188
               + K  E +S   +K    FS    +  +K    K+  T    + +++    ++
Sbjct: 1260 EVLHAKKKE-ISAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQI 1314



 Score = 29.6 bits (65), Expect = 2.2
 Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 12/114 (10%)

Query: 85  KVEEEIQTLSQVLAAKEKHLAEIKRKLG-----INSLQELKQNIAKGWQD-VTATSAYKK 138
           K E+EI  L   +   +K L+E+K+K G     I++L     N+ K   +       +++
Sbjct: 808 KHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEE 867

Query: 139 TSETLSQAGQKASAAFSSVGSVITKKLEDVKNSPTFKSFEEKVENLKSKVGGTK 192
              TL+    K +     V     KK ED+     F   ++K E LK  +  T+
Sbjct: 868 VKMTLNDTLAKTNRELLDV----KKKFEDINQE--FVKIKDKNEILKRNLENTQ 915


>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
          Length = 822

 Score = 36.2 bits (82), Expect = 0.023
 Identities = 32/136 (23%), Positives = 63/136 (46%), Gaps = 14/136 (10%)

Query: 56  EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 115
           EE E++ A       L+ E  + + + LA   EE+    Q+L  KE+ + E+++++    
Sbjct: 285 EENENLQANEIMWNNLTAESLQVMLKTLA---EELMQTQQMLLNKEEAVLELEKRI---- 337

Query: 116 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK---ASAAFSSVGSVITKKLE--DVKN 170
             E      +   D+    + K+  E L Q+ Q+     A FS+   ++ +K++  D K 
Sbjct: 338 --EESSETCEKKSDIVLLLSQKQALEELKQSVQQLRCTEAKFSAQKELLEQKVQENDGKE 395

Query: 171 SPTFKSFEEKVENLKS 186
            P   ++EE   ++ S
Sbjct: 396 PPPVVNYEEDARSVTS 411


>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
            sapiens]
          Length = 1939

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 36/137 (26%), Positives = 69/137 (50%), Gaps = 8/137 (5%)

Query: 56   EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 115
            E+ E++ A ++A +   E+E  EL++++  +E    TL++V   KEKH  E K K     
Sbjct: 931  EDEEEINAELTAKKRKLEDECSELKKDIDDLE---LTLAKV--EKEKHATENKVKNLTEE 985

Query: 116  LQELKQNIAKGWQDVTA-TSAYKKTSETLSQAGQKASAAFSSVGSVITKKLEDVKNS-PT 173
            +  L + IAK  ++  A   A+++T + L QA +      +     + ++++D++ S   
Sbjct: 986  MAGLDETIAKLTKEKKALQEAHQQTLDDL-QAEEDKVNTLTKAKIKLEQQVDDLEGSLEQ 1044

Query: 174  FKSFEEKVENLKSKVGG 190
             K     +E  K K+ G
Sbjct: 1045 EKKIRMDLERAKRKLEG 1061


>gi|157837985 kazrin isoform E [Homo sapiens]
          Length = 775

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 23/94 (24%), Positives = 43/94 (45%), Gaps = 5/94 (5%)

Query: 56  EEGEDVAATISATETLSEEEQEELRRELAKVEEEIQTLSQVLAAKEKHLAEIKRKLGINS 115
           +E ED    ++  + L E E+ ELRR+  +  +    L   L  K+  + E++ +L +  
Sbjct: 185 KESEDAVKALAKEKDLLEREKWELRRQAKEATDHATALRSQLDLKDNRMKELEAELAM-- 242

Query: 116 LQELKQNIAKGWQDVTATSAYKKTSETLSQAGQK 149
               KQ++A   +DV    +     ET+    Q+
Sbjct: 243 ---AKQSLATLTKDVPKRHSLAMPGETVLNGNQE 273


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.304    0.123    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,594,447
Number of Sequences: 37866
Number of extensions: 411838
Number of successful extensions: 3280
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 263
Number of HSP's that attempted gapping in prelim test: 2700
Number of HSP's gapped (non-prelim): 830
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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