Search of human proteins with 70166832

Search of human proteins with 70166832

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70166832 glutamate receptor, ionotropic, N-methyl
D-aspartate-like 1A isoform 2 [Homo sapiens]
         (211 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70166832 glutamate receptor, ionotropic, N-methyl D-aspartate...   419   e-118
gi|21915167 glutamate receptor, ionotropic, N-methyl D-aspartate...   347   4e-96
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]         233   1e-61
gi|21450705 leucine rich repeat containing 45 [Homo sapiens]           42   3e-04
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]     39   0.003
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]     39   0.003
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]       39   0.003
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]            38   0.007
gi|221219026 pleckstrin homology-like domain, family B, member 1...    36   0.027
gi|148746195 trichohyalin [Homo sapiens]                               36   0.027
gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]    35   0.047
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    35   0.047
gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens]      35   0.047
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi...    33   0.14 
gi|54607116 leiomodin 3 (fetal) [Homo sapiens]                         33   0.14 
gi|203096856 kinesin family member 7 [Homo sapiens]                    33   0.18 
gi|157785548 PAS domain containing 1 [Homo sapiens]                    33   0.18 
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    33   0.23 
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    33   0.23 
gi|87299628 biorientation of chromosomes in cell division 1-like...    33   0.23 
gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]                    33   0.23 
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo...    33   0.23 
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    33   0.23 
gi|71061468 centromere protein E [Homo sapiens]                        32   0.30 
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]    32   0.30 
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    32   0.39 
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        32   0.39 
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        32   0.39 
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         32   0.39 
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         32   0.39 

>gi|70166832 glutamate receptor, ionotropic, N-methyl
           D-aspartate-like 1A isoform 2 [Homo sapiens]
          Length = 211

 Score =  419 bits (1078), Expect = e-118
 Identities = 211/211 (100%), Positives = 211/211 (100%)

Query: 1   MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKN 60
           MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKN
Sbjct: 1   MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKN 60

Query: 61  LTGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEER 120
           LTGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEER
Sbjct: 61  LTGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEER 120

Query: 121 RRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLN 180
           RRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLN
Sbjct: 121 RRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLN 180

Query: 181 IKMRSYNPEGESSGRYREVRDEDDDWSSDEF 211
           IKMRSYNPEGESSGRYREVRDEDDDWSSDEF
Sbjct: 181 IKMRSYNPEGESSGRYREVRDEDDDWSSDEF 211


>gi|21915167 glutamate receptor, ionotropic, N-methyl
           D-aspartate-like 1A isoform 1 [Homo sapiens]
          Length = 368

 Score =  347 bits (890), Expect = 4e-96
 Identities = 174/180 (96%), Positives = 176/180 (97%)

Query: 32  ERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRK 91
           + L  + LQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRK
Sbjct: 189 DNLFIDRLQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRK 248

Query: 92  FKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEE 151
           FKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEE
Sbjct: 249 FKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEE 308

Query: 152 SLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDEF 211
           SLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDEF
Sbjct: 309 SLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDEF 368



 Score = 81.6 bits (200), Expect = 4e-16
 Identities = 42/59 (71%), Positives = 47/59 (79%)

Query: 1  MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTK 59
          MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNE     + D+G++  +  A  K
Sbjct: 1  MCSLPRGFEPQAPEDLAQRSLVELREMLKRQERLLRNEKFICKLPDKGKKIFDSFAKLK 59


>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
          Length = 550

 Score =  233 bits (593), Expect = 1e-61
 Identities = 115/115 (100%), Positives = 115/115 (100%)

Query: 97  LPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQ 156
           LPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQ
Sbjct: 436 LPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQ 495

Query: 157 KQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDEF 211
           KQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDEF
Sbjct: 496 KQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDEF 550


>gi|21450705 leucine rich repeat containing 45 [Homo sapiens]
          Length = 670

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 46/172 (26%), Positives = 80/172 (46%), Gaps = 14/172 (8%)

Query: 16  LAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYM 75
           L+++   +L E+L   E+   +  QR     + EQQ      +K L  LS+  EK     
Sbjct: 314 LSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQ 373

Query: 76  -EVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEER----RRRDKQHLDD 130
            +V E+  K    Q + F+T     RQ  +S   +     I +EER    +RR +Q L+D
Sbjct: 374 NQVDELERKFRCQQEQLFQT-----RQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLED 428

Query: 131 ITAARLLPLHHMPTQLLSIEESLALQKQQ----KQNYEEMQAKLAAQKLAER 178
             + R+  + HM   L   E+++  + Q+    + + EE  +++ A  L+ER
Sbjct: 429 SESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSER 480


>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
          Length = 1884

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 9/131 (6%)

Query: 46  DQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRK---FKTNVLPFRQN 102
           +QG  Q+E+N    N+T  +SG E K     +   +  NP+  L K   FKT   P   +
Sbjct: 533 NQGTNQTEQNGQVMNIT--NSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSS 590

Query: 103 DSSSHCQ----KSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQ 158
            S+   +     S +P  +  RR+   +H+  +       L       L I+   + ++ 
Sbjct: 591 ISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEI 650

Query: 159 QKQNYEEMQAK 169
           +K+ Y +M  +
Sbjct: 651 KKKKYNQMPVR 661


>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
          Length = 1816

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 9/131 (6%)

Query: 46  DQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRK---FKTNVLPFRQN 102
           +QG  Q+E+N    N+T  +SG E K     +   +  NP+  L K   FKT   P   +
Sbjct: 486 NQGTNQTEQNGQVMNIT--NSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSS 543

Query: 103 DSSSHCQ----KSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQ 158
            S+   +     S +P  +  RR+   +H+  +       L       L I+   + ++ 
Sbjct: 544 ISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEI 603

Query: 159 QKQNYEEMQAK 169
           +K+ Y +M  +
Sbjct: 604 KKKKYNQMPVR 614


>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
          Length = 1863

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 31/131 (23%), Positives = 56/131 (42%), Gaps = 9/131 (6%)

Query: 46  DQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRK---FKTNVLPFRQN 102
           +QG  Q+E+N    N+T  +SG E K     +   +  NP+  L K   FKT   P   +
Sbjct: 533 NQGTNQTEQNGQVMNIT--NSGHENKTKGDSIQNEKNPNPIESLEKESAFKTKAEPISSS 590

Query: 103 DSSSHCQ----KSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQ 158
            S+   +     S +P  +  RR+   +H+  +       L       L I+   + ++ 
Sbjct: 591 ISNMELELNIHNSKAPKKNRLRRKSSTRHIHALELVVSRNLSPPNCTELQIDSCSSSEEI 650

Query: 159 QKQNYEEMQAK 169
           +K+ Y +M  +
Sbjct: 651 KKKKYNQMPVR 661


>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
          Length = 1123

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 37/173 (21%), Positives = 78/173 (45%), Gaps = 10/173 (5%)

Query: 4   LPRGFEP-QAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNL- 61
           LP   EP Q+P +  +++ V   + L  + RL ++ ++  T A  G+++ ++    ++  
Sbjct: 798 LPEASEPPQSPSEKRKKTFVGEPQRLGSETRLPQH-IREATAAPHGKRKRKKKKRPEDTA 856

Query: 62  -TGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEER 120
            + L  G  ++     +     +  +P +R+ +    P + N     C   G   SS +R
Sbjct: 857 ASALQEGQTQRQPGSPMYRREGQAQLPAVRRQEDGTQP-QVNGQQVGCVTDGHHASSRKR 915

Query: 121 RRRDKQHLDDITAARLLPLHHMPTQL-----LSIEESLALQKQQKQNYEEMQA 168
           RR+  + L +       PL H  + +      ++EES   +K++K+  E  +A
Sbjct: 916 RRKGAEGLGEEGGLHQDPLRHSCSPMGDGDPEAMEESPRKKKKKKRKQETQRA 968


>gi|221219026 pleckstrin homology-like domain, family B, member 1
            isoform b [Homo sapiens]
          Length = 1319

 Score = 35.8 bits (81), Expect = 0.027
 Identities = 50/178 (28%), Positives = 71/178 (39%), Gaps = 33/178 (18%)

Query: 24   LREMLKRQERLLRNELQRITIADQGEQQSEENASTKN--LTGLSSGTEK----------- 70
            LR + KR+ERL   + Q   I  Q  Q+SE  A  KN  L  L    EK           
Sbjct: 838  LRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSL 897

Query: 71   -------------KPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISS 117
                         K  Y   ++  A +P+P+ R   +  LP     SSS  Q S   +++
Sbjct: 898  TGGRPFPKTTSTLKEVYRSKMDGEATSPLPRTR---SGPLPSSSGSSSSSSQLS---VAT 951

Query: 118  EERRRRDKQHLDDITAARLLPLHHMPT-QLLSIEESLALQKQQKQNYEEMQAKLAAQK 174
              R    K  L        LP +   T Q +  +  LALQ++ +Q  EE + +LA  K
Sbjct: 952  LGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELK 1009


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 35.8 bits (81), Expect = 0.027
 Identities = 43/201 (21%), Positives = 87/201 (43%), Gaps = 20/201 (9%)

Query: 26   EMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNP 85
            E+ + +E+LLR E ++  + ++  Q  EE    +    L  G E++    + LE + +  
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL-GEERETRRRQELERQYRKE 1083

Query: 86   VPQLRKFKTNVL-----PFRQNDSSSHC------QKSGSPISSEERRRRDKQHLDDITAA 134
              +L++ +  +L       R+ +    C      Q+    +  EER +R +Q L+     
Sbjct: 1084 -EELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYRE 1142

Query: 135  RLLPLHHMPTQLLSIE------ESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNP 188
                +     QLL  E      + L  Q ++++  ++ + +L  ++  +R   + R Y  
Sbjct: 1143 EE-EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201

Query: 189  EGESSGRYREVRDEDDDWSSD 209
            E E   + R+ R  D+D  SD
Sbjct: 1202 EEELQRQKRKQRYRDEDQRSD 1222



 Score = 32.3 bits (72), Expect = 0.30
 Identities = 37/195 (18%), Positives = 79/195 (40%), Gaps = 15/195 (7%)

Query: 23   ELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRA 82
            E +E  +RQ R    ELQ +   +Q +++       +   GL    E++    +  + + 
Sbjct: 815  EEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874

Query: 83   KNPVPQLRKFKTNVL---PFRQND---SSSHCQKSGSPISSEERRRRDKQHLDDITAARL 136
            +  + + RK + + L   P  Q          Q+    +  EER +R +Q  +       
Sbjct: 875  RWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE------- 927

Query: 137  LPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPE-GESSGR 195
               +    QL   EE L  ++++K+  +E + +    K  ++   ++    PE      R
Sbjct: 928  -RQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER 986

Query: 196  YREVRDEDDDWSSDE 210
             ++ R+E++    +E
Sbjct: 987  EKKYREEEELQQEEE 1001



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 42/212 (19%), Positives = 85/212 (40%), Gaps = 25/212 (11%)

Query: 9   EPQAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGT 68
           E +  E   +R   E R+ LKR+E   R+E +R     + +Q   +    +    L    
Sbjct: 439 EQERREQRLKREQEERRDWLKREEETERHEQER-----RKQQLKRDQEEERRERWLKLEE 493

Query: 69  EKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSP----ISSEERR--- 121
           E++    E  E + +    + R+ +      RQ +     Q+  S        EERR   
Sbjct: 494 EERREQQERREQQLRREQEERREQRLK----RQEEEERLQQRLRSEQQLRREQEERREQL 549

Query: 122 --RRDKQHLDDITAARLL--PLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKL-- 175
             R +++ L+     + L         QLL  EE    Q+ +++  E ++ +L  +++  
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVER 609

Query: 176 ---AERLNIKMRSYNPEGESSGRYREVRDEDD 204
               ER   +++   PE E   +  +  ++++
Sbjct: 610 LEQEERREQRLKREEPEEERRQQLLKSEEQEE 641



 Score = 28.1 bits (61), Expect = 5.7
 Identities = 40/202 (19%), Positives = 76/202 (37%), Gaps = 18/202 (8%)

Query: 9    EPQAPEDLAQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGT 68
            E Q      QR  ++  + L+RQER      QR    D+  ++ E+    +    LS   
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQER----GQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576

Query: 69   EKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHL 128
              +   +E  ++R +    Q RKF  +    R+ +     ++       + + R D+Q L
Sbjct: 1577 RDRKFRLEEQKVRRQE---QERKFMEDEQQLRRQEGQQQLRQ-----ERDRKFREDEQLL 1628

Query: 129  DDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNP 188
             +    +   LH        +EE   L++Q++   E+       +K  E   +       
Sbjct: 1629 QEREEQQ---LHRQERDRKFLEEEPQLRRQER---EQQLRHDRDRKFREEEQLLQEGEEQ 1682

Query: 189  EGESSGRYREVRDEDDDWSSDE 210
            +     R R+ R+E+      E
Sbjct: 1683 QLRRQERDRKFREEEQQLRRQE 1704


>gi|146229340 mutated in colorectal cancers isoform 1 [Homo sapiens]
          Length = 1019

 Score = 35.0 bits (79), Expect = 0.047
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 8/148 (5%)

Query: 52  SEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKS 111
           S  + ST + T  S  TE    + +  E R K+ + QL+  +  V        S H    
Sbjct: 733 SNSHTSTTSSTASSCDTE----FTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHID-- 786

Query: 112 GSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLA 171
             P+S + + R D Q LD   A  +  L  M  ++  ++  L L +++K+  E   +   
Sbjct: 787 --PLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTRE 844

Query: 172 AQKLAERLNIKMRSYNPEGESSGRYREV 199
           AQ+ A  ++I+      E +   R R +
Sbjct: 845 AQEQAYLVHIEHLKSEVEEQKEQRMRSL 872


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 35.0 bits (79), Expect = 0.047
 Identities = 23/72 (31%), Positives = 38/72 (52%), Gaps = 1/72 (1%)

Query: 18   QRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEV 77
            +R L+ELR  + +QERLL++  + +  A+Q +++S E      LT      +K    +EV
Sbjct: 2276 ERELLELRTKVSKQERLLQSTTEHLKNANQ-QKESMEQFIVSQLTRTHDVLKKARTNLEV 2334

Query: 78   LEMRAKNPVPQL 89
              +RA    P L
Sbjct: 2335 KSLRALPCTPAL 2346


>gi|4505129 mutated in colorectal cancers isoform 2 [Homo sapiens]
          Length = 829

 Score = 35.0 bits (79), Expect = 0.047
 Identities = 36/148 (24%), Positives = 63/148 (42%), Gaps = 8/148 (5%)

Query: 52  SEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKS 111
           S  + ST + T  S  TE    + +  E R K+ + QL+  +  V        S H    
Sbjct: 543 SNSHTSTTSSTASSCDTE----FTKEDEQRLKDYIQQLKNDRAAVKLTMLELESIHID-- 596

Query: 112 GSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLA 171
             P+S + + R D Q LD   A  +  L  M  ++  ++  L L +++K+  E   +   
Sbjct: 597 --PLSYDVKPRGDSQRLDLENAVLMQELMAMKEEMAELKAQLYLLEKEKKALELKLSTRE 654

Query: 172 AQKLAERLNIKMRSYNPEGESSGRYREV 199
           AQ+ A  ++I+      E +   R R +
Sbjct: 655 AQEQAYLVHIEHLKSEVEEQKEQRMRSL 682


>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
           sapiens]
          Length = 1341

 Score = 33.5 bits (75), Expect = 0.14
 Identities = 52/219 (23%), Positives = 95/219 (43%), Gaps = 25/219 (11%)

Query: 8   FEP--QAPEDLAQRSLVELREMLKRQERLLRNELQRIT--IADQGEQQSEENASTKNLTG 63
           F+P  Q  E+++Q S +  ++ L++Q+ LLR  L+R     A+  E  +E      +  G
Sbjct: 121 FQPNSQIGEEMSQNSFI--KQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEG 178

Query: 64  LSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRR 123
           ++S     P +   LE R +  + +    K++ +   + DS     + G   SS  R+ R
Sbjct: 179 VAS--LLPPDFQSSLE-RPELELSRHSPRKSSSISEEKGDSDDEKPRKGERRSSRVRQAR 235

Query: 124 ----------DKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQ 173
                      ++  D  T +R L +     + L  EE    +++++++ EE +     Q
Sbjct: 236 AAKLSEGSQPAEEEEDQETPSRNLRVR--ADRNLKTEEEEEEEEEEEEDDEEEEGDDEGQ 293

Query: 174 KLAERLNIKMRSYNPEGESSGRYR--EVRDEDDDWSSDE 210
           K  E   +K   +  EGE   R +  E+ DE     S E
Sbjct: 294 KSREAPILK--EFKEEGEEIPRVKPEEMMDERPKTRSQE 330


>gi|54607116 leiomodin 3 (fetal) [Homo sapiens]
          Length = 560

 Score = 33.5 bits (75), Expect = 0.14
 Identities = 43/168 (25%), Positives = 72/168 (42%), Gaps = 23/168 (13%)

Query: 45  ADQGEQQSEENASTKNLTGLSSGTEKK-PHYMEVLEMRAKNPVPQLRKFKTNVLPFRQND 103
           +DQ E   EE    + L  LS+   K+    MEV+      PV  ++K +T+  P     
Sbjct: 8   SDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPP----- 62

Query: 104 SSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNY 163
           + +   KS       E+  R           R+L    +P   +  EE     K Q+++ 
Sbjct: 63  TGNFNHKSLVDYMYWEKASR-----------RMLEEERVPVTFVKSEE-----KTQEEHE 106

Query: 164 E-EMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDEDDDWSSDE 210
           E E + K  AQ L E+LN ++ +   E + S   +E  +ED++   D+
Sbjct: 107 EIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDD 154


>gi|203096856 kinesin family member 7 [Homo sapiens]
          Length = 1343

 Score = 33.1 bits (74), Expect = 0.18
 Identities = 39/177 (22%), Positives = 76/177 (42%), Gaps = 22/177 (12%)

Query: 18  QRSLVEL--REMLKRQERLLRNELQRITIADQGEQQ--SEENASTKNLTGLSSGTEKKPH 73
           QR L EL  +E+    ER    E +R   A Q + Q   E+  +T+ L  LS+ +EK+  
Sbjct: 763 QRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQ 822

Query: 74  YME-----------VLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRR 122
            +E            L+ R +    Q R+ +  +       S    +     +  E++++
Sbjct: 823 ELERNVQLMRQQQGQLQRRLREETEQKRRLEAEM-------SKRQHRVKELELKHEQQQK 875

Query: 123 RDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERL 179
             K   ++I A +          ++S+E+   +++Q+K   +EM+  L  ++  E L
Sbjct: 876 ILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEEL 932


>gi|157785548 PAS domain containing 1 [Homo sapiens]
          Length = 773

 Score = 33.1 bits (74), Expect = 0.18
 Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 13/149 (8%)

Query: 18  QRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEV 77
           Q+ LV+  + LK Q+R LR +LQ+  + +Q + Q ++    K         EKK   ++ 
Sbjct: 479 QQQLVQQEQHLKEQQRQLREQLQQ--LREQRKVQKQKKMQEKKKLQEQKMQEKKK--LQE 534

Query: 78  LEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSP-----ISSEERRRRDKQHLDDIT 132
              + K  + + +K++  +L     +     Q    P     I   ER +   Q+  D++
Sbjct: 535 QRRQKKKKLQERKKWQGQMLQKEPEEEQQKQQLQEQPLKHNVIVGNERVQICLQNPRDVS 594

Query: 133 AARLLPLHHMPTQLLSIEESLALQKQQKQ 161
               +PL + P + L  +  + +Q+  +Q
Sbjct: 595 ----VPLCNHPVRFLQAQPIVPVQRAAEQ 619


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 32.7 bits (73), Expect = 0.23
 Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 30/172 (17%)

Query: 17  AQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYME 76
           AQ  +  L E+LK  E    ++ ++I  A+   Q  ++N    NL           H  +
Sbjct: 754 AQAEVDRLLEILKEVENEKNDKDKKI--AELERQVKDQNKKVANLK----------HKEQ 801

Query: 77  VLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQ----KSGSPISSEERRRRDKQHLDDIT 132
           V + ++   + + R+ + N+     NDSS   Q    K    I   E   R+      IT
Sbjct: 802 VEKKKSAQMLEEARRREDNL-----NDSSQQLQDSLRKKDDRIEELEEALRESVQ---IT 853

Query: 133 AARLLPLHHMPTQLLS----IEESLALQKQQKQNYEEMQAKLAA--QKLAER 178
           A R + L    +   +    +EE L   ++ KQ  E M+AKL++  Q LAE+
Sbjct: 854 AEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEK 905



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 23  ELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRA 82
           ++ E+L   E++ + EL+ +       QQS     T +LT L +  E++ H  EVLEM+ 
Sbjct: 873 QVEELLMAMEKV-KQELESMKAKLSSTQQSLAEKET-HLTNLRA--ERRKHLEEVLEMKQ 928

Query: 83  KNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERR 121
           +  +  + +   N+     + S    Q+  + +  E+ R
Sbjct: 929 EALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDR 967


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 32.7 bits (73), Expect = 0.23
 Identities = 45/172 (26%), Positives = 74/172 (43%), Gaps = 30/172 (17%)

Query: 17  AQRSLVELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYME 76
           AQ  +  L E+LK  E    ++ ++I  A+   Q  ++N    NL           H  +
Sbjct: 726 AQAEVDRLLEILKEVENEKNDKDKKI--AELERQVKDQNKKVANLK----------HKEQ 773

Query: 77  VLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQ----KSGSPISSEERRRRDKQHLDDIT 132
           V + ++   + + R+ + N+     NDSS   Q    K    I   E   R+      IT
Sbjct: 774 VEKKKSAQMLEEARRREDNL-----NDSSQQLQDSLRKKDDRIEELEEALRESVQ---IT 825

Query: 133 AARLLPLHHMPTQLLS----IEESLALQKQQKQNYEEMQAKLAA--QKLAER 178
           A R + L    +   +    +EE L   ++ KQ  E M+AKL++  Q LAE+
Sbjct: 826 AEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEK 877



 Score = 29.6 bits (65), Expect = 2.0
 Identities = 24/99 (24%), Positives = 47/99 (47%), Gaps = 4/99 (4%)

Query: 23  ELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRA 82
           ++ E+L   E++ + EL+ +       QQS     T +LT L +  E++ H  EVLEM+ 
Sbjct: 845 QVEELLMAMEKV-KQELESMKAKLSSTQQSLAEKET-HLTNLRA--ERRKHLEEVLEMKQ 900

Query: 83  KNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERR 121
           +  +  + +   N+     + S    Q+  + +  E+ R
Sbjct: 901 EALLAAISEKDANIALLELSSSKKKTQEEVAALKREKDR 939


>gi|87299628 biorientation of chromosomes in cell division 1-like
           [Homo sapiens]
          Length = 3051

 Score = 32.7 bits (73), Expect = 0.23
 Identities = 31/153 (20%), Positives = 70/153 (45%), Gaps = 12/153 (7%)

Query: 29  KRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQ 88
           +++ERLLR ++ R  + ++ +Q++E+  S+K      S  + +    + LE +A      
Sbjct: 500 EKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEV 559

Query: 89  LRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLS 148
           L++ K       +  + S  +K  S   + E   + KQ  ++ +   L    H       
Sbjct: 560 LKERKV----LEKKVALSKKRKKDS--RNVEENSKKKQQYEEDSKETLKTSEHCE----- 608

Query: 149 IEESLALQKQQKQNYEEMQAKLAAQKLAERLNI 181
            +E ++  K+ K  + + +    A++L+E L++
Sbjct: 609 -KEKISSSKELKHVHAKSEPSKPARRLSESLHV 640


>gi|36031016 CTCL tumor antigen L14-2 [Homo sapiens]
          Length = 898

 Score = 32.7 bits (73), Expect = 0.23
 Identities = 39/203 (19%), Positives = 83/203 (40%), Gaps = 29/203 (14%)

Query: 21  LVELREMLKRQERLLRNELQRITIADQ-------GEQQSEE--------NASTKNLTGLS 65
           L + +E++ RQ+  ++N L ++  ADQ       G+Q+ E         N+   +L    
Sbjct: 519 LSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDI 578

Query: 66  SGTEKKPHYMEVLEMRAKNPVPQLRKFKTNV------LPFRQNDSSSHCQK--------S 111
            G+ K+   + +   R  +   QL+    ++      +   ++   S C++         
Sbjct: 579 EGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLE 638

Query: 112 GSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLA 171
              +  EE R+ + Q L    A R   +  + TQ+  +++ L  Q+++  +  +   K  
Sbjct: 639 SRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQL 698

Query: 172 AQKLAERLNIKMRSYNPEGESSG 194
            Q   +   ++  SY+ E  S G
Sbjct: 699 QQARRKLDQVESGSYDKEVSSMG 721


>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
           [Homo sapiens]
          Length = 666

 Score = 32.7 bits (73), Expect = 0.23
 Identities = 37/164 (22%), Positives = 75/164 (45%), Gaps = 24/164 (14%)

Query: 52  SEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKS 111
           S ++A+ + +T   +    K   + +L M  ++P  Q    +T ++   +    +  ++ 
Sbjct: 495 STDSATHRKMTLSLADRCSKTQKIRILPMAGRDPECQ----RTEMIKKEEERLRASIRRE 550

Query: 112 GSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESL---ALQKQQKQNYEEMQA 168
                S++RR R+KQH   ++A+ L P  +   +    EES+   A++ + K    E +A
Sbjct: 551 -----SQQRRMREKQHQRGLSASYLEPDRYDEEE--EGEESISLAAIKNRYKGGIREERA 603

Query: 169 KLAA---------QKLAERLNIKMRSYNPEGESSGRYREVRDED 203
           ++ +          K    L  K  + + EGE SG+ R+  D+D
Sbjct: 604 RIYSSDSDEGSEEDKAQRLLKAKKLTSDEEGEPSGK-RKAEDDD 646


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 32.7 bits (73), Expect = 0.23
 Identities = 40/185 (21%), Positives = 77/185 (41%), Gaps = 8/185 (4%)

Query: 24  LREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAK 83
           LR   K +ER     L+R   A+Q  +Q  E    + L  +    E++    +VL+ R +
Sbjct: 526 LRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREER--LRKVLQARER 583

Query: 84  NPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMP 143
               +  K K     F Q D  +   K       + +++   + ++++ A R        
Sbjct: 584 VEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARR 643

Query: 144 TQLLSIEESLA-----LQKQQKQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYRE 198
            + L  EE        LQK++++  E ++    A++LAE+   + R      E   R +E
Sbjct: 644 LRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE-QERREQERREQE 702

Query: 199 VRDED 203
            R+++
Sbjct: 703 RREQE 707


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 32.3 bits (72), Expect = 0.30
 Identities = 34/176 (19%), Positives = 78/176 (44%), Gaps = 10/176 (5%)

Query: 28   LKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRAKNPVP 87
            LK QE  + NEL+     +  E+++E +   K L  ++   + K    E+ E   +  + 
Sbjct: 1486 LKEQEETI-NELR----VNLSEKETEISTIQKQLEAINDKLQNK--IQEIYEKEEQFNIK 1538

Query: 88   QLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLL 147
            Q+ + +  V   +Q     H +   S + S E +  +  +    +   +  +     ++ 
Sbjct: 1539 QISEVQEKVNELKQ--FKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMK 1596

Query: 148  SIEESLALQKQQ-KQNYEEMQAKLAAQKLAERLNIKMRSYNPEGESSGRYREVRDE 202
             ++E+L +++ Q K+N +E+ AK+   +  E   +KM + N   E       ++++
Sbjct: 1597 RVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQ 1652



 Score = 31.6 bits (70), Expect = 0.51
 Identities = 41/188 (21%), Positives = 80/188 (42%), Gaps = 31/188 (16%)

Query: 20   SLVELREMLKRQ-----ERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKP-H 73
            S++  +E LK       E  + N+ +   + D+ ++Q E  A  KN      G   +   
Sbjct: 1061 SVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCD 1120

Query: 74   YMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITA 133
             +  +E + K    QL++ +  +L  ++    S  QK  + I + +   ++K+       
Sbjct: 1121 RLAEVEEKLKEKSQQLQEKQQQLLNVQEE--MSEMQKKINEIENLKNELKNKE------- 1171

Query: 134  ARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIK-------MRSY 186
               L L HM T+ L + + L       +NYEE+++    +K+ + L          +R Y
Sbjct: 1172 ---LTLEHMETERLELAQKL------NENYEEVKSITKERKVLKELQKSFETERDHLRGY 1222

Query: 187  NPEGESSG 194
              E E++G
Sbjct: 1223 IREIEATG 1230


>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
          Length = 938

 Score = 32.3 bits (72), Expect = 0.30
 Identities = 35/150 (23%), Positives = 60/150 (40%), Gaps = 4/150 (2%)

Query: 64  LSSGTEKKPHYMEVLEMRAKNPVPQLRKFKTNVLPFRQNDSSSHCQKS-GSPISSEERRR 122
           LS  T    +  E L    K   P     K  ++ F   D + H +    + + S  R  
Sbjct: 775 LSKSTNSHKNATEDLYEVDKLKQPSTSTEKEKLIRFIGEDENVHSKPLFETDVLSSWRES 834

Query: 123 RDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQK--QNYEEMQAKLAAQKLAERLN 180
             +  L       +  + HM  +LL +E   A Q ++K    YE++   L   K  E L 
Sbjct: 835 AKQGTLAQKYLEAMAVIEHMQEKLLEVENR-ARQAEEKFEDAYEKLHHTLIKNKDLEELV 893

Query: 181 IKMRSYNPEGESSGRYREVRDEDDDWSSDE 210
           +  R  + E + +   REV++E++    +E
Sbjct: 894 MTSRKESKEEKENQDEREVKEEEEQQEEEE 923


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
           theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 32.0 bits (71), Expect = 0.39
 Identities = 54/228 (23%), Positives = 93/228 (40%), Gaps = 45/228 (19%)

Query: 23  ELREMLKRQER---------------LLRN--ELQRITIADQGEQQSEENASTKNLTGLS 65
           EL+E LK QE+               L+++  E QRI   D  EQQ EE  +T  L    
Sbjct: 683 ELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLE-RE 741

Query: 66  SGTEKKPHYMEVLEMR---------AKNPV--PQLRKFKTNVLPFRQN--DSSSHCQKSG 112
              E K     +LE R         A+  V   +L++F+  +   R N  +     +K  
Sbjct: 742 KALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEE 801

Query: 113 SPIS------SEERRRRDKQHLDD-------ITAARLLPLHHMPTQLLSIEESLALQKQQ 159
             I+       EE+RR ++Q L +         A R   L     ++  +EE    ++Q+
Sbjct: 802 RRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQR 861

Query: 160 KQNYEEMQAKLAAQ-KLAERLNIKMRSYNPEGESSGRYREVRDEDDDW 206
           +   EE + +   + +L +    +  S   + +S G +R+  + D +W
Sbjct: 862 ELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEW 909


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 32.0 bits (71), Expect = 0.39
 Identities = 30/155 (19%), Positives = 69/155 (44%), Gaps = 23/155 (14%)

Query: 23   ELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRA 82
            +LRE  +RQ++ +  E QR+  + +  ++ +  A          G  +K   ++ LE   
Sbjct: 2529 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEA--------EEGVRRKQEELQQLE--- 2577

Query: 83   KNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHM 142
                 Q R+ +  +L           Q        EE+ R    H +++TA+++     +
Sbjct: 2578 -----QQRRQQEELLAEENQRLREQLQ------LLEEQHRAALAHSEEVTASQVAATKTL 2626

Query: 143  PTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAE 177
            P    ++ +  A + + + +++ ++ K++AQ+L E
Sbjct: 2627 PNGRDAL-DGPAAEAEPEHSFDGLRRKVSAQRLQE 2660


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 32.0 bits (71), Expect = 0.39
 Identities = 30/155 (19%), Positives = 69/155 (44%), Gaps = 23/155 (14%)

Query: 23   ELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRA 82
            +LRE  +RQ++ +  E QR+  + +  ++ +  A          G  +K   ++ LE   
Sbjct: 2533 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEA--------EEGVRRKQEELQQLE--- 2581

Query: 83   KNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHM 142
                 Q R+ +  +L           Q        EE+ R    H +++TA+++     +
Sbjct: 2582 -----QQRRQQEELLAEENQRLREQLQ------LLEEQHRAALAHSEEVTASQVAATKTL 2630

Query: 143  PTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAE 177
            P    ++ +  A + + + +++ ++ K++AQ+L E
Sbjct: 2631 PNGRDAL-DGPAAEAEPEHSFDGLRRKVSAQRLQE 2664


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 32.0 bits (71), Expect = 0.39
 Identities = 30/155 (19%), Positives = 69/155 (44%), Gaps = 23/155 (14%)

Query: 23   ELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRA 82
            +LRE  +RQ++ +  E QR+  + +  ++ +  A          G  +K   ++ LE   
Sbjct: 2529 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEA--------EEGVRRKQEELQQLE--- 2577

Query: 83   KNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHM 142
                 Q R+ +  +L           Q        EE+ R    H +++TA+++     +
Sbjct: 2578 -----QQRRQQEELLAEENQRLREQLQ------LLEEQHRAALAHSEEVTASQVAATKTL 2626

Query: 143  PTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAE 177
            P    ++ +  A + + + +++ ++ K++AQ+L E
Sbjct: 2627 PNGRDAL-DGPAAEAEPEHSFDGLRRKVSAQRLQE 2660


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 32.0 bits (71), Expect = 0.39
 Identities = 30/155 (19%), Positives = 69/155 (44%), Gaps = 23/155 (14%)

Query: 23   ELREMLKRQERLLRNELQRITIADQGEQQSEENASTKNLTGLSSGTEKKPHYMEVLEMRA 82
            +LRE  +RQ++ +  E QR+  + +  ++ +  A          G  +K   ++ LE   
Sbjct: 2497 QLREEQQRQQQQMEQERQRLVASMEEARRRQHEA--------EEGVRRKQEELQQLE--- 2545

Query: 83   KNPVPQLRKFKTNVLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHM 142
                 Q R+ +  +L           Q        EE+ R    H +++TA+++     +
Sbjct: 2546 -----QQRRQQEELLAEENQRLREQLQ------LLEEQHRAALAHSEEVTASQVAATKTL 2594

Query: 143  PTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAE 177
            P    ++ +  A + + + +++ ++ K++AQ+L E
Sbjct: 2595 PNGRDAL-DGPAAEAEPEHSFDGLRRKVSAQRLQE 2628


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.127    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,829,997
Number of Sequences: 37866
Number of extensions: 326656
Number of successful extensions: 1630
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 1544
Number of HSP's gapped (non-prelim): 236
length of query: 211
length of database: 18,247,518
effective HSP length: 98
effective length of query: 113
effective length of database: 14,536,650
effective search space: 1642641450
effective search space used: 1642641450
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.