Guide to the Human Genome
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Search of human proteins with 13899327

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13899327 nuclear receptor interacting protein 2 [Homo
sapiens]
         (281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13899327 nuclear receptor interacting protein 2 [Homo sapiens]     571   e-163
gi|11034819 nuclear receptor interacting protein 3 [Homo sapiens]     149   2e-36
gi|62955833 DNA-damage inducible protein 2 [Homo sapiens]              56   4e-08
gi|48717485 DDI1, DNA-damage inducible 1, homolog 1 [Homo sapiens]     55   7e-08
gi|88196790 coiled-coil domain containing 88 [Homo sapiens]            37   0.019
gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Ho...    34   0.13 
gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo...    34   0.13 
gi|4885487 myeloid leukemia factor 2 [Homo sapiens]                    34   0.16 
gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]             33   0.21 
gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]             33   0.21 
gi|239758051 PREDICTED: hypothetical protein [Homo sapiens]            33   0.36 
gi|150170729 microtubule associated serine/threonine kinase 3 [H...    33   0.36 
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...    32   0.48 
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]               32   0.48 
gi|38045915 pregnancy-associated plasma protein A preproprotein ...    32   0.62 
gi|46409266 coiled-coil domain containing 74B [Homo sapiens]           32   0.62 
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi...    32   0.81 
gi|20270307 coiled-coil domain containing 74A [Homo sapiens]           32   0.81 
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora...    31   1.1  
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora...    31   1.1  
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora...    31   1.1  
gi|242247193 SH2B adaptor protein 2 [Homo sapiens]                     31   1.1  
gi|109452608 chromosome 14 open reading frame 140 isoform b [Hom...    31   1.1  
gi|109452611 chromosome 14 open reading frame 140 isoform a [Hom...    31   1.1  
gi|210032790 hypothetical protein LOC27146 [Homo sapiens]              31   1.4  
gi|115334682 SNAP25-interacting protein [Homo sapiens]                 31   1.4  
gi|194097341 period 1 [Homo sapiens]                                   30   1.8  
gi|239751870 PREDICTED: hypothetical protein XP_002348033 [Homo ...    30   1.8  
gi|87162461 fragile X mental retardation 2 [Homo sapiens]              30   1.8  
gi|93277115 ataxin 7-like 2 [Homo sapiens]                             30   1.8  

>gi|13899327 nuclear receptor interacting protein 2 [Homo sapiens]
          Length = 281

 Score =  571 bits (1471), Expect = e-163
 Identities = 281/281 (100%), Positives = 281/281 (100%)

Query: 1   MLFIFPLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRD 60
           MLFIFPLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRD
Sbjct: 1   MLFIFPLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRD 60

Query: 61  EGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVI 120
           EGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVI
Sbjct: 61  EGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVI 120

Query: 121 QRRLVEGNPNWLQGEPPRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQ 180
           QRRLVEGNPNWLQGEPPRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQ
Sbjct: 121 QRRLVEGNPNWLQGEPPRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQ 180

Query: 181 YNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQVEQLELQLGQETVVCSAQVVDAESPEF 240
           YNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQVEQLELQLGQETVVCSAQVVDAESPEF
Sbjct: 181 YNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQVEQLELQLGQETVVCSAQVVDAESPEF 240

Query: 241 CLGLQTLLSLKCCIDLEHGVLRLKAPFSELPFLPLYQEPGQ 281
           CLGLQTLLSLKCCIDLEHGVLRLKAPFSELPFLPLYQEPGQ
Sbjct: 241 CLGLQTLLSLKCCIDLEHGVLRLKAPFSELPFLPLYQEPGQ 281


>gi|11034819 nuclear receptor interacting protein 3 [Homo sapiens]
          Length = 241

 Score =  149 bits (377), Expect = 2e-36
 Identities = 90/216 (41%), Positives = 127/216 (58%), Gaps = 11/216 (5%)

Query: 69  QEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGN 128
           +E  +R+ A L QQRR+KQA QF+HKDSADLLPLD LK+LG+SKD+QP +++QRRL+E N
Sbjct: 13  KETDMREAASLRQQRRMKQAVQFIHKDSADLLPLDGLKKLGSSKDMQPHNILQRRLMETN 72

Query: 129 PNWLQGEP----PRMQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRI 184
            + L+  P        + ++  +S       E   +LV+C+C  + ++  VDTG  YN I
Sbjct: 73  LSKLRSGPRVPWASKTNKLNQAKSEGLKKSEEDDMILVSCQCAGKDVKALVDTGCLYNLI 132

Query: 185 SAGCLSRLGLEKRVLK-ASAGDLAPGP-----PTQVEQLELQLGQETVVCSAQVVDAESP 238
           S  C+ RLGL++ V      G+    P       Q+E L + LG   + C A VVD    
Sbjct: 133 SLACVDRLGLKEHVKSHKHEGEKLSLPRHLKVVGQIEHLVITLGSLRLDCPAAVVDDNEK 192

Query: 239 EFCLGLQTLLSLKCCIDLE-HGVLRLKAPFSELPFL 273
              LGLQTL SLKC I+L+ H ++  K    E+PF+
Sbjct: 193 NLSLGLQTLRSLKCIINLDKHRLIMGKTDKEEIPFV 228


>gi|62955833 DNA-damage inducible protein 2 [Homo sapiens]
          Length = 399

 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 6/124 (4%)

Query: 156 EIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQ-- 213
           ++  L +NCK     ++  VD+G Q   +S  C  R  + + V +  AG +A G  TQ  
Sbjct: 232 QVVMLYINCKVNGHPVKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAG-IAKGVGTQKI 290

Query: 214 ---VEQLELQLGQETVVCSAQVVDAESPEFCLGLQTLLSLKCCIDLEHGVLRLKAPFSEL 270
              V   ++Q+  + + CS  +++ +  +  LGL  L   +C IDL+  VL +    S+ 
Sbjct: 291 IGRVHLAQVQIEGDFLPCSFSILEEQPMDMLLGLDMLKRHQCSIDLKKNVLVIGTTGSQT 350

Query: 271 PFLP 274
            FLP
Sbjct: 351 TFLP 354


>gi|48717485 DDI1, DNA-damage inducible 1, homolog 1 [Homo sapiens]
          Length = 396

 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 36/124 (29%), Positives = 61/124 (49%), Gaps = 6/124 (4%)

Query: 156 EIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCLSRLGLEKRVLKASAGDLAPGPPTQ-- 213
           ++  L +NCK     L+  VD+G Q   +S  C  R  + + V +  AG +A G  TQ  
Sbjct: 240 QVTMLYINCKVNGHPLKAFVDSGAQMTIMSQACAERCNIMRLVDRRWAG-VAKGVGTQRI 298

Query: 214 ---VEQLELQLGQETVVCSAQVVDAESPEFCLGLQTLLSLKCCIDLEHGVLRLKAPFSEL 270
              V   ++Q+  + + CS  +++ +  +  LGL  L   +C IDL+  VL +    ++ 
Sbjct: 299 IGRVHLAQIQIEGDFLQCSFSILEDQPMDMLLGLDMLRRHQCSIDLKKNVLVIGTTGTQT 358

Query: 271 PFLP 274
            FLP
Sbjct: 359 YFLP 362


>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
          Length = 1476

 Score = 37.0 bits (84), Expect = 0.019
 Identities = 32/114 (28%), Positives = 52/114 (45%), Gaps = 5/114 (4%)

Query: 34  SVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQRRLKQATQ--F 91
           S+ PPP SP   P AGA  + Q+  R+    R R  E + R+   L Q  + +   Q   
Sbjct: 429 SLEPPPGSPGEAPLAGAAPSLQDEVREAEAGRLRTLERENRELRGLLQVLQGQPGGQHPL 488

Query: 92  LHKDSAD-LLP-LDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQDLI 143
           L     D +LP L+   +   + D  P+ ++Q+   +G P  L   PP +  ++
Sbjct: 489 LEAPREDPVLPVLEEAPQTPVAFDHSPQGLVQKAR-DGGPQALDLAPPALDSVL 541


>gi|195927037 DNA (cytosine-5-)-methyltransferase 1 isoform a [Homo
           sapiens]
          Length = 1632

 Score = 34.3 bits (77), Expect = 0.13
 Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 8/135 (5%)

Query: 24  QRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQ- 82
           +R+   SRE    P P+       +G  + K+E R ++ E R R Q  +   +  L ++ 
Sbjct: 219 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEP 278

Query: 83  -RRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQD 141
            R  +   Q    +  D    D  K     KDL      +RR  E  P  +  +    +D
Sbjct: 279 DREARAGVQADEDEDGD--EKDEKKHRSQPKDL----AAKRRPEEKEPEKVNPQISDEKD 332

Query: 142 LIHGQESRRKTSRTE 156
               +E RRKT+  E
Sbjct: 333 EDEKEEKRRKTTPKE 347


>gi|4503351 DNA (cytosine-5-)-methyltransferase 1 isoform b [Homo
           sapiens]
          Length = 1616

 Score = 34.3 bits (77), Expect = 0.13
 Identities = 34/135 (25%), Positives = 54/135 (40%), Gaps = 8/135 (5%)

Query: 24  QRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQ- 82
           +R+   SRE    P P+       +G  + K+E R ++ E R R Q  +   +  L ++ 
Sbjct: 203 KRRRVTSRERVARPLPAEEPERAKSGTRTEKEEERDEKEEKRLRSQTKEPTPKQKLKEEP 262

Query: 83  -RRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQD 141
            R  +   Q    +  D    D  K     KDL      +RR  E  P  +  +    +D
Sbjct: 263 DREARAGVQADEDEDGD--EKDEKKHRSQPKDL----AAKRRPEEKEPEKVNPQISDEKD 316

Query: 142 LIHGQESRRKTSRTE 156
               +E RRKT+  E
Sbjct: 317 EDEKEEKRRKTTPKE 331


>gi|4885487 myeloid leukemia factor 2 [Homo sapiens]
          Length = 248

 Score = 33.9 bits (76), Expect = 0.16
 Identities = 26/107 (24%), Positives = 45/107 (42%), Gaps = 7/107 (6%)

Query: 40  SSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQRR------LKQATQFLH 93
           +S   + P G   T++  R  +           +RDRAH+ Q+ R       ++   +++
Sbjct: 124 TSEMRSAPGGIRETRRTVRDSDSGLEQMSIGHHIRDRAHILQRSRNHRTGDQEERQDYIN 183

Query: 94  KDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGE-PPRM 139
            D ++    D   R  TS+  Q R +  RRL        + E PPR+
Sbjct: 184 LDESEAAAFDDEWRRETSRFRQQRPLEFRRLESSGAGGRRAEGPPRL 230


>gi|62750349 histone deacetylase 5 isoform 3 [Homo sapiens]
          Length = 1123

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 10/94 (10%)

Query: 8   SLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTK-QEARRDEGEART 66
           SLP  P CW          A  +  D  +PP S P  TPP+  +        RD+   R 
Sbjct: 207 SLPQHPKCWG---------AHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRK 257

Query: 67  RGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLL 100
              E  L+ R+ L Q+   ++++  L +    ++
Sbjct: 258 TASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVI 291


>gi|62750347 histone deacetylase 5 isoform 1 [Homo sapiens]
          Length = 1122

 Score = 33.5 bits (75), Expect = 0.21
 Identities = 24/94 (25%), Positives = 39/94 (41%), Gaps = 10/94 (10%)

Query: 8   SLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTK-QEARRDEGEART 66
           SLP  P CW          A  +  D  +PP S P  TPP+  +        RD+   R 
Sbjct: 206 SLPQHPKCWG---------AHHASLDQSSPPQSGPPGTPPSYKLPLPGPYDSRDDFPLRK 256

Query: 67  RGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLL 100
              E  L+ R+ L Q+   ++++  L +    ++
Sbjct: 257 TASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVI 290


>gi|239758051 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 243

 Score = 32.7 bits (73), Expect = 0.36
 Identities = 35/128 (27%), Positives = 48/128 (37%), Gaps = 18/128 (14%)

Query: 16  WKESCSTGQRQAGRSREDSVTPPP----------SSPWPTPPAGAMSTKQEARRDEGEAR 65
           W   CSTG+ + G+      T  P          + P PTP AG  ++K       G   
Sbjct: 14  WSPRCSTGRAELGKGEPSPCTGRPEQRGRRKSSLAPPAPTPDAGPQTSKDLEPPPHG--- 70

Query: 66  TRGQEAQLRDRAHLSQQRRLKQATQFLHKDSADLLPLD-SLKRLGTSKDLQPRSVIQRRL 124
              QEA        +  R  +Q    L + S  +LPL  +L   G+S    P    QRR+
Sbjct: 71  --CQEADRGGSWGATTSRPFRQNLSDLGRHS--VLPLKRNLCPGGSSLGAPPLRTPQRRV 126

Query: 125 VEGNPNWL 132
                 WL
Sbjct: 127 TLAAQRWL 134


>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
            sapiens]
          Length = 1309

 Score = 32.7 bits (73), Expect = 0.36
 Identities = 27/64 (42%), Positives = 32/64 (50%), Gaps = 17/64 (26%)

Query: 37   PPPSSPWPT---PPAGAMSTKQE----------ARRDEGEA--RTRGQEAQL--RDRAHL 79
            PPP SP P    PPA A S +              R +GEA  RTRG EA+L    R HL
Sbjct: 1197 PPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDGEAGRRTRGPEAELVVMRRLHL 1256

Query: 80   SQQR 83
            S++R
Sbjct: 1257 SERR 1260


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score = 32.3 bits (72), Expect = 0.48
 Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 14/153 (9%)

Query: 74  RDRAHLSQQRRLKQATQFLHKDSADLLPLDSLK--RLGTSKDLQPRSVIQRRL-VEGNPN 130
           ++   LSQ   +KQ  Q LH D        +LK  R G+   L   +V  R L +     
Sbjct: 449 KEAQELSQNSAIKQDAQSLHGDIPQKQREITLKGFRNGSFGVLVATNVAARGLDIPEVDL 508

Query: 131 WLQGEPPR-MQDLIHGQESRRKTSRTEIPALLVNCKCQDQLLRVAVDTGTQYNRISAGCL 189
            +Q  PP+ ++  IH      +  RT +       K + QL++V    G ++ RI     
Sbjct: 509 VIQSSPPKDVESYIHRSGRTGRAGRTGVCICFYQHKEEYQLVQVEQKAGIKFKRIGVPSA 568

Query: 190 SRLGLEKRVLKASAGD----LAPGPPTQVEQLE 218
           +       ++KAS+ D    L   PPT +   +
Sbjct: 569 T------EIIKASSKDAIRLLDSVPPTAISHFK 595


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score = 32.3 bits (72), Expect = 0.48
 Identities = 39/165 (23%), Positives = 52/165 (31%), Gaps = 42/165 (25%)

Query: 25  RQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEAR-----------RDEGEARTRGQEAQL 73
           R  GRS      PP     PTPPAGA S  +E+             + GE R  G     
Sbjct: 225 RGGGRSGGGLAGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPP--- 281

Query: 74  RDRAHLSQQRRLKQATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQ 133
                 S  ++        H+  A  LP        + +D  P       +    PN LQ
Sbjct: 282 -PLTATSPPQQPHALPPHAHRRPASALP--------SRRDGTPTKTTPCEIPPPFPNLLQ 332

Query: 134 GEPP-------------------RMQDLIHGQESRRKTSRTEIPA 159
             PP                   R+  L H +E    T   ++PA
Sbjct: 333 HRPPLLAFPQAKSASRTPGDGVSRLPVLCHSKEPAGSTPAPQVPA 377


>gi|38045915 pregnancy-associated plasma protein A preproprotein
          [Homo sapiens]
          Length = 1627

 Score = 32.0 bits (71), Expect = 0.62
 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 10/69 (14%)

Query: 10 PWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAM-STKQEARRDEGEARTRG 68
          P RP+    +C+T   +A R R  S  PPP      PP GA  + +   RR + EAR   
Sbjct: 37 PPRPAAGPATCAT---RAARGRRASPPPPP------PPGGAWEAVRVPRRRQQREARGAT 87

Query: 69 QEAQLRDRA 77
          +E     RA
Sbjct: 88 EEPSPPSRA 96


>gi|46409266 coiled-coil domain containing 74B [Homo sapiens]
          Length = 380

 Score = 32.0 bits (71), Expect = 0.62
 Identities = 26/92 (28%), Positives = 44/92 (47%), Gaps = 13/92 (14%)

Query: 36  TPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKD 95
           T PPSSP P       S ++  R   G    R Q  QLR      +   L+++ QFL + 
Sbjct: 10  TRPPSSPTPG------SRRRRQRPSVGVQSLRPQSPQLRQSDPQKRNLDLEKSLQFLQQQ 63

Query: 96  SADLL-----PLDSLKRLGTSKDLQPRSVIQR 122
            +++L      ++ LKR   +KDL+ + ++ +
Sbjct: 64  HSEMLAKLHEEIEHLKR--ENKDLRYKLIMNQ 93


>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
           sapiens]
          Length = 1478

 Score = 31.6 bits (70), Expect = 0.81
 Identities = 58/222 (26%), Positives = 91/222 (40%), Gaps = 39/222 (17%)

Query: 52  STKQEARRDEGEARTRGQEAQLRDRA--HLSQQRRLKQATQFLHKDSADLLPLDSLKRLG 109
           S+ QEA     E +   QEAQL D      SQ+  L+QA + L K+  +++  + L   G
Sbjct: 579 SSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLE-G 637

Query: 110 TSKDLQPR-SVIQRR--LVEGNPNWLQGEPPRMQDL----------IHGQESRRKTSRTE 156
             + LQ     +Q+R   ++G+   L+ E   ++ L          +   +   K    E
Sbjct: 638 KLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAE 697

Query: 157 IPALLVNCKCQDQLLRVAVDTGTQY--------NRISAGCLSRLGLEKRVLKASAGDLAP 208
             A+L + + + Q LR  V+   Q           + + C  +  L + VL A  G    
Sbjct: 698 KEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIE-VLTAEKGQQGV 756

Query: 209 GPPTQVE-------------QLELQLGQETVVCSAQVVDAES 237
           GPPT  E             QLE+  G E     AQVVD ++
Sbjct: 757 GPPTDNEARELAAQLALSQAQLEVHQG-EVQRLQAQVVDLQA 797


>gi|20270307 coiled-coil domain containing 74A [Homo sapiens]
          Length = 378

 Score = 31.6 bits (70), Expect = 0.81
 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 13/92 (14%)

Query: 36  TPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQQRRLKQATQFLHKD 95
           T PPSSP P       S ++  R   G    R Q  QLR      +   L+++ QFL + 
Sbjct: 10  TRPPSSPTPG------SRRRRQRPSVGVQSLRPQSPQLRQSDPQKRNLDLEKSLQFLQQQ 63

Query: 96  SADLL-----PLDSLKRLGTSKDLQPRSVIQR 122
            +++L      ++ LKR   +KDL  + ++ +
Sbjct: 64  HSEMLAKLHEEIEHLKR--ENKDLHYKLIMNQ 93


>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 1 [Homo
            sapiens]
          Length = 1834

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 4/101 (3%)

Query: 28   GRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQL---RDRAHLSQQRR 84
            G S +  + PPPS+     P+  ++  +  +R+E +     ++A+L   R+R    Q+R+
Sbjct: 1380 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1439

Query: 85   LKQ-ATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRL 124
            L Q  TQ L+      L    +K    S   +P+  + R L
Sbjct: 1440 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIREL 1480


>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 2 [Homo
            sapiens]
          Length = 1651

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 4/101 (3%)

Query: 28   GRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQL---RDRAHLSQQRR 84
            G S +  + PPPS+     P+  ++  +  +R+E +     ++A+L   R+R    Q+R+
Sbjct: 1381 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1440

Query: 85   LKQ-ATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRL 124
            L Q  TQ L+      L    +K    S   +P+  + R L
Sbjct: 1441 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIREL 1481


>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
            homolog, Drosophila); translocated to, 4 isoform 3 [Homo
            sapiens]
          Length = 1612

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 4/101 (3%)

Query: 28   GRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQL---RDRAHLSQQRR 84
            G S +  + PPPS+     P+  ++  +  +R+E +     ++A+L   R+R    Q+R+
Sbjct: 1365 GMSMDLPLPPPPSANQIGLPSAQVAAAERRKREEHQRWYEKEKARLEEERERKRREQERK 1424

Query: 85   LKQ-ATQFLHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRL 124
            L Q  TQ L+      L    +K    S   +P+  + R L
Sbjct: 1425 LGQMRTQSLNPAPFSPLTAQQMKPEKPSTLQRPQETVIREL 1465


>gi|242247193 SH2B adaptor protein 2 [Homo sapiens]
          Length = 675

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 27/84 (32%), Positives = 37/84 (44%), Gaps = 7/84 (8%)

Query: 6   PLSLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTK-QEARRDEGEA 64
           P + P  P+CW +  S GQ     S   +  PP S   P+  AGA S+    +    G A
Sbjct: 571 PPAAPASPACWSD--SPGQHYFS-SLAAAACPPAS---PSDAAGASSSSASSSSAASGPA 624

Query: 65  RTRGQEAQLRDRAHLSQQRRLKQA 88
             R  E QL  R+  +   RL +A
Sbjct: 625 PPRPVEGQLSARSRSNSAERLLEA 648


>gi|109452608 chromosome 14 open reading frame 140 isoform b [Homo
           sapiens]
          Length = 275

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 17/97 (17%)

Query: 8   SLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGE---- 63
           + P +P   ++SCSTG  +AG   + +V P P  P         S++    R++G     
Sbjct: 138 AFPLKPMVHRKSCSTG--EAGTDGDHNVYPRPPEP------REFSSRNFGVRNQGNFSVV 189

Query: 64  ----ARTRGQEAQLR-DRAHLSQQRRLKQATQFLHKD 95
               A T+ ++A    DR    Q RRL+ A + L ++
Sbjct: 190 GTVLAATQAEKAVANFDRTEWVQIRRLEAAGESLEEE 226


>gi|109452611 chromosome 14 open reading frame 140 isoform a [Homo
           sapiens]
          Length = 456

 Score = 31.2 bits (69), Expect = 1.1
 Identities = 27/97 (27%), Positives = 45/97 (46%), Gaps = 17/97 (17%)

Query: 8   SLPWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGE---- 63
           + P +P   ++SCSTG  +AG   + +V P P  P         S++    R++G     
Sbjct: 138 AFPLKPMVHRKSCSTG--EAGTDGDHNVYPRPPEP------REFSSRNFGVRNQGNFSVV 189

Query: 64  ----ARTRGQEAQLR-DRAHLSQQRRLKQATQFLHKD 95
               A T+ ++A    DR    Q RRL+ A + L ++
Sbjct: 190 GTVLAATQAEKAVANFDRTEWVQIRRLEAAGESLEEE 226


>gi|210032790 hypothetical protein LOC27146 [Homo sapiens]
          Length = 1060

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 3/73 (4%)

Query: 44  PTPPAGAMSTKQEARRDEGEARTRGQEAQLRDRAHLSQ-QRRLKQATQFLHKDSADLLPL 102
           P PP G++  ++ ++    E   + Q+A+L  +A +SQ Q+ L+Q T    +D   L  L
Sbjct: 576 PQPPLGSLLKEKTSKIQRLEEDWQSQKAKL--QAQVSQMQQALEQCTSNYREDLQALKQL 633

Query: 103 DSLKRLGTSKDLQ 115
             L+R    ++LQ
Sbjct: 634 SDLEREKLQRELQ 646


>gi|115334682 SNAP25-interacting protein [Homo sapiens]
          Length = 1183

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 14/44 (31%), Positives = 22/44 (50%)

Query: 21  STGQRQAGRSREDSVTPPPSSPWPTPPAGAMSTKQEARRDEGEA 64
           S+ Q+ A  +      PPP SP+  PP+     +Q  R+D G +
Sbjct: 473 SSPQKLADVAAPPGGPPPPHSPYSGPPSRGSPVRQSFRKDSGSS 516


>gi|194097341 period 1 [Homo sapiens]
          Length = 1290

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 10/11 (90%), Positives = 11/11 (100%)

Query: 38  PPSSPWPTPPA 48
           PPS+PWPTPPA
Sbjct: 863 PPSTPWPTPPA 873


>gi|239751870 PREDICTED: hypothetical protein XP_002348033 [Homo
           sapiens]
          Length = 508

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 16/41 (39%), Positives = 17/41 (41%)

Query: 34  SVTPPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQLR 74
           S +P PS   P  P G  S    AR   G   TRG    LR
Sbjct: 210 STSPKPSGHQPAGPTGTCSGTHSARLRPGGPHTRGMPGSLR 250


>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
          Length = 1311

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 2/38 (5%)

Query: 10  PWRPSCWKESCSTGQRQAGRSREDSVTPPPSSPWPTPP 47
           P +P   +E+ S+  R+A R +E+ + PPP SP P  P
Sbjct: 889 PHKPPNTRENNSS--RRANRRKEEKLFPPPLSPLPEDP 924


>gi|93277115 ataxin 7-like 2 [Homo sapiens]
          Length = 722

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 10/109 (9%)

Query: 37  PPPSSPWPTPPAGAMSTKQEARRDEGEARTRGQEAQL--RDRAHLSQQRRLKQ---ATQF 91
           PPP +P  +     ++ +  A R  G  +T  +E     R R H   ++  K        
Sbjct: 115 PPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGG 174

Query: 92  LHKDSADLLPLDSLKRLGTSKDLQPRSVIQRRLVEGNPNWLQGEPPRMQ 140
           L KDS    P+        SK+   R  I+    EG+ +W +G PP  +
Sbjct: 175 LTKDSPGKPPMAP-----PSKEPPGRENIEIIPSEGSSHWAEGSPPEKE 218


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,500,210
Number of Sequences: 37866
Number of extensions: 611797
Number of successful extensions: 4530
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 4432
Number of HSP's gapped (non-prelim): 156
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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