Search of human proteins with 13699824

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13699824 kinesin family member 11 [Homo sapiens]
         (1056 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13699824 kinesin family member 11 [Homo sapiens]                  2057   0.0  
gi|46852174 kinesin family member 3A [Homo sapiens]                   338   2e-92
gi|4758646 kinesin family member 3B [Homo sapiens]                    320   4e-87
gi|170784809 kinesin family member 17 isoform b [Homo sapiens]        306   5e-83
gi|170784807 kinesin family member 17 isoform a [Homo sapiens]        306   5e-83
gi|41352705 kinesin family member 3C [Homo sapiens]                   306   7e-83
gi|150010604 kinesin family member 4B [Homo sapiens]                  271   2e-72
gi|4758650 kinesin family member 5C [Homo sapiens]                    270   5e-72
gi|45446749 kinesin family member 5A [Homo sapiens]                   270   7e-72
gi|116686122 kinesin family member 4 [Homo sapiens]                   269   1e-71
gi|4758648 kinesin family member 5B [Homo sapiens]                    267   3e-71
gi|9910266 kinesin family member 15 [Homo sapiens]                    261   3e-69
gi|71061468 centromere protein E [Homo sapiens]                       257   4e-68
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]        257   5e-68
gi|30794488 kinesin family member 27 [Homo sapiens]                   239   1e-62
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]     236   1e-61
gi|41393563 kinesin family member 1B isoform b [Homo sapiens]         236   1e-61
gi|38569484 kinesin family member 21A [Homo sapiens]                  236   1e-61
gi|83716024 kinesin family member 21B [Homo sapiens]                  235   1e-61
gi|157738629 kinesin family member 13A isoform d [Homo sapiens]       234   3e-61
gi|157738627 kinesin family member 13A isoform c [Homo sapiens]       234   3e-61
gi|157738625 kinesin family member 13A isoform b [Homo sapiens]       234   3e-61
gi|157738621 kinesin family member 13A isoform a [Homo sapiens]       234   3e-61
gi|46852172 kinesin family member 13B [Homo sapiens]                  233   7e-61
gi|156616271 kinesin family member 19 [Homo sapiens]                  231   2e-60
gi|148612831 kinesin family member 18A [Homo sapiens]                 231   3e-60
gi|40254834 kinesin family member 1C [Homo sapiens]                   231   4e-60
gi|122937289 kinesin family member 18B [Homo sapiens]                 230   5e-60
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]      229   1e-59
gi|7661878 kinesin family member 14 [Homo sapiens]                    225   2e-58

>gi|13699824 kinesin family member 11 [Homo sapiens]
          Length = 1056

 Score = 2057 bits (5330), Expect = 0.0
 Identities = 1056/1056 (100%), Positives = 1056/1056 (100%)

Query: 1    MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADK 60
            MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADK
Sbjct: 1    MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADK 60

Query: 61   SSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERS 120
            SSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERS
Sbjct: 61   SSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERS 120

Query: 121  PNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSE 180
            PNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSE
Sbjct: 121  PNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSE 180

Query: 181  RLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFS 240
            RLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFS
Sbjct: 181  RLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFS 240

Query: 241  VTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
            VTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT
Sbjct: 241  VTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300

Query: 301  ALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIL 360
            ALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIL
Sbjct: 301  ALVERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNIL 360

Query: 361  NKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIV 420
            NKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIV
Sbjct: 361  NKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIV 420

Query: 421  ELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY 480
            ELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY
Sbjct: 421  ELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY 480

Query: 481  ITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNS 540
            ITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNS
Sbjct: 481  ITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNS 540

Query: 541  LFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHV 600
            LFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHV
Sbjct: 541  LFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHV 600

Query: 601  SQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKT 660
            SQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKT
Sbjct: 601  SQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKT 660

Query: 661  SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ 720
            SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ
Sbjct: 661  SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ 720

Query: 721  ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS 780
            ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS
Sbjct: 721  ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS 780

Query: 781  QELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNER 840
            QELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNER
Sbjct: 781  QELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNER 840

Query: 841  EQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNE 900
            EQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNE
Sbjct: 841  EQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNE 900

Query: 901  TIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLM 960
            TIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLM
Sbjct: 901  TIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLM 960

Query: 961  MLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGK 1020
            MLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGK
Sbjct: 961  MLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGK 1020

Query: 1021 DKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL 1056
            DKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL
Sbjct: 1021 DKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL 1056


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score =  338 bits (867), Expect = 2e-92
 Identities = 224/592 (37%), Positives = 319/592 (53%), Gaps = 65/592 (10%)

Query: 11  KKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDM 70
           +K E   N++VVVRCRP N  E+       V  D +R  ++V     +++   KT+TFD 
Sbjct: 7   EKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPP-KTFTFDT 65

Query: 71  VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
           VFG  +KQ+DVY     PI+D V+ GYN TIFAYGQTGTGKTFTMEG R+  E       
Sbjct: 66  VFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPE------- 118

Query: 131 PLAGIIPRTLHQIFEKLT--DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDP 188
            L GIIP +   IF  +   +  T F V+VS LEIYNEE+ DLL    D ++RL++ + P
Sbjct: 119 -LRGIIPNSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLG--KDQTQRLEVKERP 175

Query: 189 RNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKET 248
               GV IK L    V+N D++ +I+  G   R+  AT MN +SSRSH++F++TI   E 
Sbjct: 176 --DVGVYIKDLSAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEK 233

Query: 249 TIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE-RTP 307
            IDG   V++GKL+LVDLAGSE   ++GA  +R +EA  IN SL TLG VI+ALV+ ++ 
Sbjct: 234 GIDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKST 293

Query: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
           HVPYR SKLTR+LQDSLGG ++T + A I PA  N +ET+STL YA+RAKNI NK  +N+
Sbjct: 294 HVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINE 353

Query: 368 KLTKKALIKEYTEEIERLKRDLAAAREKNGVYIS---------------EENFRVMSGKL 412
              K AL++++ +EIE LK+ L    E +G  IS                E  +   GK 
Sbjct: 354 D-PKDALLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKK 412

Query: 413 TVQEEQIVELIEKIGAVEEELNRVTELFMDNKN----ELDQCKSDLQNKTQE-------- 460
            V  ++++E+  KI    + L    ++  + +N    EL++ + DL    QE        
Sbjct: 413 KVSPDKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKL 472

Query: 461 -----------------LETTQKHLQETKLQL----VKEEYITSALESTEEKLHDAASKL 499
                             E  +K L+E+ ++L     + E +   LE  E++  D   K 
Sbjct: 473 SALEKKVIVGGVDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEKY 532

Query: 500 LNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKD 551
            +  EE       L        A     A+ Q    + +  L  N+ +L ++
Sbjct: 533 TSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQREIEGLLENIRQLSRE 584


>gi|4758646 kinesin family member 3B [Homo sapiens]
          Length = 747

 Score =  320 bits (820), Expect = 4e-87
 Identities = 215/593 (36%), Positives = 319/593 (53%), Gaps = 69/593 (11%)

Query: 12  KEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMV 71
           K +  ++++VVVRCRP N  E+ AS   +V+ D    +VSV+          KT+TFD V
Sbjct: 3   KLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDAV 62

Query: 72  FGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP 131
           +  + KQ ++Y     P++D V+ G+N TIFAYGQTGTGKT+TMEG R   E+       
Sbjct: 63  YDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEK------- 115

Query: 132 LAGIIPRTLHQIFEKLT-DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRN 190
             G+IP +   IF  ++     ++ V+ S LEIY EE+ DLL  S D ++RL++ + P  
Sbjct: 116 -RGVIPNSFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLL--SKDQTKRLELKERPDT 172

Query: 191 KRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTI 250
             GV +K L      +  E+  ++  G   R+  AT MN +SSRSH++F +TI   E  +
Sbjct: 173 --GVYVKDLSSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGL 230

Query: 251 DGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE-RTPHV 309
           DGE  +++GKLNLVDLAGSE   ++GA  +R +EA  IN SL  LG VI+ALV+ ++ H+
Sbjct: 231 DGENHIRVGKLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHI 290

Query: 310 PYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKL 369
           PYR+SKLTR+LQDSLGG  +T ++A + PAS N+EETL+TL YA+RAKNI NKP VN+  
Sbjct: 291 PYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVNED- 349

Query: 370 TKKALIKEYTEEIERLKRDL-----------------------AAAREKNGVYISEEN-- 404
            K AL++E+ EEI RLK  L                           E+ G    EE   
Sbjct: 350 PKDALLREFQEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDD 409

Query: 405 ----FRVMSGKLTVQEEQIVE-----LIEKIGAVEEELNRVTELFMD------------- 442
               +R    KL +++  IVE       EK+  ++E+  ++ +L  +             
Sbjct: 410 KDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKA 469

Query: 443 -NKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEE---KLHDAASK 498
                L   K+ + +  ++ +  ++  QE   Q  +E  I   +ES +E   +L +  S 
Sbjct: 470 MESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSS 529

Query: 499 LLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKD 551
           L   V+  TK +  L SKL   KA + H+ + + I  K    L     EL ++
Sbjct: 530 LQQEVDIKTKKLKKLFSKLQAVKA-EIHDLQEEHI--KERQELEQTQNELTRE 579


>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
          Length = 1028

 Score =  306 bits (785), Expect = 5e-83
 Identities = 193/488 (39%), Positives = 279/488 (57%), Gaps = 34/488 (6%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
           ++VVVRCRP N  ER+     +V  D  R +  ++  G AD+   K +TFD  +      
Sbjct: 6   VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPP-KQFTFDGAYHVDHVT 64

Query: 79  IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
             +Y  +  P+++ V  GYN TIFAYGQTG+GK+FTM+G   P  +         GIIPR
Sbjct: 65  EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQ--------RGIIPR 116

Query: 139 TLHQIFEKLT-DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIK 197
               +FE +     T+F V+ S LEIYNE++ DLL   +D  ++L++ + P  ++GV +K
Sbjct: 117 AFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLLG--ADTKQKLELKEHP--EKGVYVK 172

Query: 198 GLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK 257
           GL   TVH+  +   I+E G   R+   TLMN  SSRSHS+F+++I M      G++ ++
Sbjct: 173 GLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLR 232

Query: 258 IGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE-RTPHVPYRESKL 316
            GKLNLVDLAGSE   ++GA  +R +EA  IN SL  LG VI+ALV+ R  HVPYR+SKL
Sbjct: 233 AGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKL 292

Query: 317 TRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIK 376
           TR+LQDSLGG T+T ++A +SPA  N +ETLSTL YA+RAKNI NKP +N+   K AL++
Sbjct: 293 TRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINED-PKDALLR 351

Query: 377 EYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRV 436
           EY EEI++LK  L      + +        ++S ++     Q          VEE+L   
Sbjct: 352 EYQEEIKKLKAILTQQMSPSSL------SALLSRQVPPDPVQ----------VEEKLLPQ 395

Query: 437 TELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAA 496
             +  D + E    + + + +   L+   K  QE++ +L  EE IT+   S + +L    
Sbjct: 396 PVIQHDVEAEKQLIREEYEERLARLKADYKAEQESRARL--EEDITAMRNSYDVRLSTLE 453

Query: 497 SKLLNTVE 504
             L    E
Sbjct: 454 ENLRKETE 461


>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
          Length = 1029

 Score =  306 bits (785), Expect = 5e-83
 Identities = 193/488 (39%), Positives = 279/488 (57%), Gaps = 34/488 (6%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
           ++VVVRCRP N  ER+     +V  D  R +  ++  G AD+   K +TFD  +      
Sbjct: 6   VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPP-KQFTFDGAYHVDHVT 64

Query: 79  IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
             +Y  +  P+++ V  GYN TIFAYGQTG+GK+FTM+G   P  +         GIIPR
Sbjct: 65  EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQ--------RGIIPR 116

Query: 139 TLHQIFEKLT-DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIK 197
               +FE +     T+F V+ S LEIYNE++ DLL   +D  ++L++ + P  ++GV +K
Sbjct: 117 AFEHVFESVQCAENTKFLVRASYLEIYNEDVRDLLG--ADTKQKLELKEHP--EKGVYVK 172

Query: 198 GLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK 257
           GL   TVH+  +   I+E G   R+   TLMN  SSRSHS+F+++I M      G++ ++
Sbjct: 173 GLSMHTVHSVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLR 232

Query: 258 IGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE-RTPHVPYRESKL 316
            GKLNLVDLAGSE   ++GA  +R +EA  IN SL  LG VI+ALV+ R  HVPYR+SKL
Sbjct: 233 AGKLNLVDLAGSERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKL 292

Query: 317 TRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIK 376
           TR+LQDSLGG T+T ++A +SPA  N +ETLSTL YA+RAKNI NKP +N+   K AL++
Sbjct: 293 TRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRINED-PKDALLR 351

Query: 377 EYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRV 436
           EY EEI++LK  L      + +        ++S ++     Q          VEE+L   
Sbjct: 352 EYQEEIKKLKAILTQQMSPSSL------SALLSRQVPPDPVQ----------VEEKLLPQ 395

Query: 437 TELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAA 496
             +  D + E    + + + +   L+   K  QE++ +L  EE IT+   S + +L    
Sbjct: 396 PVIQHDVEAEKQLIREEYEERLARLKADYKAEQESRARL--EEDITAMRNSYDVRLSTLE 453

Query: 497 SKLLNTVE 504
             L    E
Sbjct: 454 ENLRKETE 461


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score =  306 bits (784), Expect = 7e-83
 Identities = 218/651 (33%), Positives = 328/651 (50%), Gaps = 77/651 (11%)

Query: 12  KEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMV 71
           K +  + ++VV RCRP +  E  A    I+  D    +V++R    A     KT+TFD V
Sbjct: 4   KTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAV 63

Query: 72  FGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP 131
           + AS+KQ D+Y   V P++D V+ G+N T+FAYGQTGTGKT+TM+G        TW E  
Sbjct: 64  YDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQG--------TWVEPE 115

Query: 132 LAGIIPRTLHQIFEKLT-DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRN 190
           L G+IP     IF  ++     ++ V+ S LEIY EE+ DLL  S +  +RL++ ++P  
Sbjct: 116 LRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLL--SKEPGKRLELKENP-- 171

Query: 191 KRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTI 250
           + GV IK L      N  E+  ++  G   R   +T MN  SSRSH++F +T+   E   
Sbjct: 172 ETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGS 231

Query: 251 DGEELVKIGKLNLVDLAGSENIGRS------------------------GAVDKRAREAG 286
           DG++ +++GKLNLVDLAGSE   ++                        GA  +R +EA 
Sbjct: 232 DGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEAS 291

Query: 287 NINQSLLTLGRVITALV-ERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEE 345
            IN SL  LG VI AL   R+ H+PYR+SKLTR+LQDSLGG  +T ++AT+ PAS + +E
Sbjct: 292 KINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDE 351

Query: 346 TLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENF 405
           +LSTL +A+RAKNI NKP VN+   K  L++E+ EEI RLK  L    EK G+       
Sbjct: 352 SLSTLRFANRAKNIKNKPRVNED-PKDTLLREFQEEIARLKAQL----EKRGMLGKRPRR 406

Query: 406 RVMSGKLTVQEEQIV---ELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELE 462
           +    K  V          +IE   A EE+         DN N     +  L++  +  +
Sbjct: 407 KSSRRKKAVSAPPGYPEGPVIEAWVAEEED---------DNNNNHRPPQPILESALE--K 455

Query: 463 TTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKA 522
             + +LQE K +L +E+   +A++     + +   KLL   E+  +D+       +   A
Sbjct: 456 NMENYLQEQKERLEEEK---AAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAA 512

Query: 523 VDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNL------LSSSVS 576
             +       I G+N           I D +++Q+ MLE+ +            +   + 
Sbjct: 513 KYKAMESKLLIGGRN-----------IMDHTNEQQKMLELKRQEIAEQKRREREMQQEMM 561

Query: 577 ALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINV 627
             D  T    G+ TS+ + V     ++  +  K Q++ AE +    E I V
Sbjct: 562 LRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRV 612


>gi|150010604 kinesin family member 4B [Homo sapiens]
          Length = 1234

 Score =  271 bits (694), Expect = 2e-72
 Identities = 244/849 (28%), Positives = 407/849 (47%), Gaps = 96/849 (11%)

Query: 11  KKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDM 70
           K+E KG  ++V +RCRP    E        +   P   +V V T         K++T+D 
Sbjct: 2   KEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD--------KSFTYDF 53

Query: 71  VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
           VF   T+Q +V+   V P++  +  GYN T+ AYGQTG+GKT++M G  +  +E     +
Sbjct: 54  VFDPCTEQEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQE----NE 109

Query: 131 PLAGIIPRTLHQIFEKLTDNGT-EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPR 189
           P  GIIPR +  +F+++      EF++KVS LEIYNEE+ DLL PS + ++ + + +DP 
Sbjct: 110 PTVGIIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQ-INIREDP- 167

Query: 190 NKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETT 249
            K G+ I GL E TV    +    LE+G   RT A+T MN+ SSRSH++F+++I  ++ +
Sbjct: 168 -KEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKS 226

Query: 250 IDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE--RTP 307
              +      KL+LVDLAGSE   ++ A   R +E  NIN+ LL LG VI+AL +  +  
Sbjct: 227 --DKNCSFRSKLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGS 284

Query: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
            VPYR+SKLTR+LQDSLGG + T +IA +SPA  NLEETLSTL YA RA+ I NKP VN 
Sbjct: 285 FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNI 344

Query: 368 KLTKKAL--IKEYTEEIERL-----------------KRDLAAAREKNGVYISEENFRVM 408
                 L  +K+  ++++ L                   +L +  EKN   + EEN + +
Sbjct: 345 DPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLV-EENEK-L 402

Query: 409 SGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHL 468
           S  L+    Q  +++E+I  + E++N      ++   +   CK DLQ   + LE  Q+  
Sbjct: 403 SRCLSKAAGQTAQMLERI-ILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLE-DQELK 460

Query: 469 QETKLQLVKEEYITSALESTEEKLHDAASKLLNTVE-----ETTKDVSGLHSKLDRKKAV 523
           +  ++    ++ IT   + ++E +   A+ +   VE     ET+ + S        + A+
Sbjct: 461 ENVEIICNLQQLIT---QLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHAL 517

Query: 524 DQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNL--LSSSVSALDTI 581
            Q     + +    LN+     E L++  +     +  +      N+  L   V  L   
Sbjct: 518 HQAQMSKEVV---ELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQKE 574

Query: 582 TTVALGSLTSIPENVS-THVSQIFNMILKE-QSLAAESKTVLQELINVLKTDLLSSLEMI 639
               +  L +  +NV+   +S+  + +L+E +   A+ K  L E   +LK  L  S E  
Sbjct: 575 KEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLLK--LKESTERT 632

Query: 640 LSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVE 699
           +S     I  + +Q   + +     A+K    K++ D                 +  L E
Sbjct: 633 VSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKD---------------KEVIQLKE 677

Query: 700 SQKQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSK 759
             ++                 EL KL   + ++   L  K E        +++ + QK +
Sbjct: 678 RDRK--------------RQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDAL-QKQR 722

Query: 760 DIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLV---EESVKHSDKLNGNLEKISQETE 816
           ++ +K     +      +G +  +RN+     +++   EE+ +H + L  + + ++Q+  
Sbjct: 723 EVTDK---RKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVV 779

Query: 817 QRCESLNTR 825
           Q  E   +R
Sbjct: 780 QLKEKKESR 788



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 108/536 (20%), Positives = 215/536 (40%), Gaps = 76/536 (14%)

Query: 337 SPASLNLEETLSTLEYAHRAKNILNKPEVNQKLT-KKALIKEYTEEIERLKRDLAAAREK 395
           SP +    +  +T    H+A+      E+N  L  K+AL+++ T+   +L+         
Sbjct: 501 SPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVRKMTQNDNQLQPIQ------ 554

Query: 396 NGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELN--RVTELFMDNKNELDQCKSD 453
              +  ++N + +  ++   +++  EL+ ++   ++ +N  +++E       EL+   +D
Sbjct: 555 ---FQYQDNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIAD 611

Query: 454 LQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKL----HDAASKLLNTVEETTKD 509
           L+ K  E     K  + T+  + K       +++   +L     + A K     ++  K+
Sbjct: 612 LKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKE 671

Query: 510 VSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL------IKDGSSKQKAMLEVH 563
           V  L  + DRK+  +    E    F K  + L    EE       +KD   KQ+ + +  
Sbjct: 672 VIQLKER-DRKRQYELLKLERN--FQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKR 728

Query: 564 KTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTH-VSQIFNMILKEQSLAAESKTVLQ 622
           K       S     +       LG+   I   VST    +  N +L+++ + A+    L+
Sbjct: 729 K----ETQSHGKEGIAARVRNWLGN--EIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLK 782

Query: 623 ELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSIL 682
           E     K +   +    L     S+ +++ Q+       L   D I  Q + L+  + + 
Sbjct: 783 E-----KKESRENPPPKLRKCTFSLSEVHGQV-------LESEDCITKQIESLETEMELR 830

Query: 683 CNNLHELQENTICSLVESQ-KQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCE 741
              + +LQ+  + +  E + KQC    E++ TI +      C L  L  E    L     
Sbjct: 831 SAQIADLQQKLLDAESEDRPKQCW---ENIATILEAK----CALKYLIGE----LVSSKI 879

Query: 742 NIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQ----ELRNFNQEGTKLVEES 797
           ++ K  +S++++  + S   + KM F  Q   ++ +   Q     +   +QE    +   
Sbjct: 880 HVTKLENSLRQS--KASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEKVLYLVSQ 937

Query: 798 VKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQ 853
           ++ S      LEK + E EQ              Q VS+L  +++EL  + EV  Q
Sbjct: 938 LQESQMAEKQLEKSASEKEQ--------------QLVSTLQCQDEELEKMREVCEQ 979


>gi|4758650 kinesin family member 5C [Homo sapiens]
          Length = 957

 Score =  270 bits (690), Expect = 5e-72
 Identities = 265/925 (28%), Positives = 421/925 (45%), Gaps = 118/925 (12%)

Query: 18  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTK 77
           +I+V+ R RP N AE       I +    + + +V  G        K Y FD V   +T 
Sbjct: 8   SIKVMCRFRPLNEAEILRGDKFIPK---FKGDETVVIG------QGKPYVFDRVLPPNTT 58

Query: 78  QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP-LAGII 136
           Q  VY +    I+ +V+ GYN TIFAYGQT +GKT TMEG+           DP L GII
Sbjct: 59  QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKL---------HDPQLMGII 109

Query: 137 PRTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGV 194
           PR  H IF+ +   D   EF +KVS  EIY +++ DLL    DVS+      + +N R  
Sbjct: 110 PRIAHDIFDHIYSMDENLEFHIKVSYFEIYLDKIRDLL----DVSKTNLAVHEDKN-RVP 164

Query: 195 IIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEE 254
            +KG  E  V + +EV  ++++G A R  A T MN +SSRSHS+F + I  K+  ++ E+
Sbjct: 165 YVKGCTERFVSSPEEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINI--KQENVETEK 222

Query: 255 LVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTP-HVPYRE 313
            +  GKL LVDLAGSE + ++GA      EA NIN+SL  LG VI+AL E T  HVPYR+
Sbjct: 223 KLS-GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRD 281

Query: 314 SKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKA 373
           SK+TRILQDSLGG  RT+I+   SP+  N  ET STL +  RAK I N   VN +LT + 
Sbjct: 282 SKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEE 341

Query: 374 LIKEYTEEIERLKR--------DLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEK 425
             K+Y +E E+ K         ++   R +NG  + E+       +  ++      +I+ 
Sbjct: 342 WKKKYEKEKEKNKTLKNVIQHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDN 401

Query: 426 IGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSAL 485
           I  V   ++  TE       E+      L +K  E+    +  ++ K Q++ ++ + ++ 
Sbjct: 402 IAPVVAGIS--TEEKEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLAST 459

Query: 486 ESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKA-VDQHNAEAQDIFGKNLNSLFNN 544
               EK+ +  ++L    E    +V  +   L+      DQ + E +D    N       
Sbjct: 460 RRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRAN------- 512

Query: 545 MEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIF 604
            E+L  + + K   +                    T T   L  L  +  +     ++I 
Sbjct: 513 -EQLTDELAQKTTTL--------------------TTTQRELSQLQELSNHQKKRATEIL 551

Query: 605 NMILKEQSLAAESKTVLQELINVLKT-------DLLSSLEMILSPTVVSILKINSQLKHI 657
           N++LK+          L E+  ++ T       D+   +E   +   + I K+ S++K +
Sbjct: 552 NLLLKD----------LGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSL 601

Query: 658 FKTSLTVADKIEDQKKELDGFLSIL--CNNLHELQENTICSLVESQKQCGNLTEDLKTIK 715
              S  +     D  ++++     L  C  L    E  I SL +  +        L+  +
Sbjct: 602 VNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQ 661

Query: 716 QTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCAD 775
            + S+EL KL         + ++K    +K   +  ++ ++  K +  +M  H +   A 
Sbjct: 662 DSLSEELAKLRAQEKMHEVSFQDK----EKEHLTRLQDAEEMKKALEQQMESHRE---AH 714

Query: 776 SDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKIS----------QETEQRCES---L 822
               S+ LR+  +E  K+++E    + KL    EK+S          QE E + E    L
Sbjct: 715 QKQLSR-LRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLL 773

Query: 823 NTRTVYFSEQ---WVSSLNEREQELHNLLEVVSQ--CCEASSSDITEKSDGRKAAHEKQH 877
           N +     E       +++   Q LHNL ++  Q        S   +  DG  +A +KQ 
Sbjct: 774 NDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQK 833

Query: 878 NIF----LDQMTIDEDKLIAQNLEL 898
             F    L+Q+T    +L+  N +L
Sbjct: 834 ISFLENNLEQLTKVHKQLVRDNADL 858


>gi|45446749 kinesin family member 5A [Homo sapiens]
          Length = 1032

 Score =  270 bits (689), Expect = 7e-72
 Identities = 269/908 (29%), Positives = 431/908 (47%), Gaps = 89/908 (9%)

Query: 18  NIQVVVRCRPFNLAERKASAHSIVECDPV-RKEVSVRTGGLADKSSRKTYTFDMVFGAST 76
           +I+V+ R RP N AE       I    P+ + + SV  GG       K Y FD VF  +T
Sbjct: 9   SIKVLCRFRPLNQAEILRGDKFI----PIFQGDDSVVIGG-------KPYVFDRVFPPNT 57

Query: 77  KQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP-LAGI 135
            Q  VY +    I+ +V+ GYN TIFAYGQT +GKT TMEG+           DP L GI
Sbjct: 58  TQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKL---------HDPQLMGI 108

Query: 136 IPRTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRG 193
           IPR    IF  +   D   EF +KVS  EIY +++ DLL    DV++      + +N R 
Sbjct: 109 IPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLL----DVTKTNLSVHEDKN-RV 163

Query: 194 VIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGE 253
             +KG  E  V + +E+  ++++G + R  A T MN +SSRSHS+F + I  K+  ++ E
Sbjct: 164 PFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINI--KQENMETE 221

Query: 254 ELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTP-HVPYR 312
           + +  GKL LVDLAGSE + ++GA      EA NIN+SL  LG VI+AL E T  +VPYR
Sbjct: 222 QKLS-GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYR 280

Query: 313 ESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKK 372
           +SK+TRILQDSLGG  RT++    SP+S N  ET STL +  RAK I N   VN +LT +
Sbjct: 281 DSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAE 340

Query: 373 ALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEE 432
              K+Y +E E+ K     A+++    +  E  R  +G+   + E++      +GA   E
Sbjct: 341 QWKKKYEKEKEKTK-----AQKETIAKLEAELSRWRNGENVPETERLAGEEAALGA---E 392

Query: 433 LNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKL 492
           L   T +  ++   +     + Q   +E+    K L +   ++ ++  +   +E  ++++
Sbjct: 393 LCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQL---IEKLKQQM 449

Query: 493 HDAASKLLNT---VEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELI 549
            D    L++T    E+  +++S L S+ D  K   +   +A +    N +     +EE  
Sbjct: 450 LDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEE-- 507

Query: 550 KDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILK 609
               S+Q  +L        + LS  V+ + ++ +  L  L  +  +    ++++ N ++K
Sbjct: 508 ---KSQQNQLLV-------DELSQKVATMLSLES-ELQRLQEVSGHQRKRIAEVLNGLMK 556

Query: 610 EQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVAD-KI 668
           + S   E   ++      L  ++  ++E   +   + I KI S++K + K    + + ++
Sbjct: 557 DLS---EFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQV 613

Query: 669 E-DQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMN 727
           E  +K E+ G     C  L    E  I SL E  +        L+    + S EL KL  
Sbjct: 614 ECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQA 673

Query: 728 LWTERFCALEEKCENIQ--KPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRN 785
             T    AL++K  + Q    +    E   +  ++  ++     +    +      EL++
Sbjct: 674 QETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKD 733

Query: 786 FNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYF-----SEQWVSSLNE- 839
            NQ   KL  E     +KL  + EK+  E  ++   L   T  +     S+Q +  L E 
Sbjct: 734 LNQ---KLQLE----LEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEET 786

Query: 840 --RE-QELHNLLEVVSQ--CCEASSSDITEKSDGRKAAHEKQHNIF----LDQMTIDEDK 890
             RE Q LHNL ++  Q        S   E  D      +KQ   F    L+Q+T    +
Sbjct: 787 VARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQ 846

Query: 891 LIAQNLEL 898
           L+  N +L
Sbjct: 847 LVRDNADL 854


>gi|116686122 kinesin family member 4 [Homo sapiens]
          Length = 1232

 Score =  269 bits (687), Expect = 1e-71
 Identities = 269/1016 (26%), Positives = 471/1016 (46%), Gaps = 100/1016 (9%)

Query: 11  KKEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDM 70
           K+E KG  ++V +RCRP    E        +   P   +V V T         K++T+D 
Sbjct: 2   KEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTD--------KSFTYDF 53

Query: 71  VFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEED 130
           VF  ST+Q +V+ + V P++  V  GYN T+ AYGQTG+GKT++M G  +  +E     +
Sbjct: 54  VFDPSTEQEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQE----NE 109

Query: 131 PLAGIIPRTLHQIFEKLTDNGT-EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPR 189
           P  G+IPR +  +F+++      EF++KVS LEIYNEE+ DLL PS + ++ + + +DP 
Sbjct: 110 PTVGVIPRVIQLLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQ-INIREDP- 167

Query: 190 NKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETT 249
            K G+ I GL E TV    +    LE+G   RT A+T MN+ SSRSH++F++++  ++ +
Sbjct: 168 -KEGIKIVGLTEKTVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKS 226

Query: 250 IDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE--RTP 307
                     KL+LVDLAGSE   ++ A   R +E  NIN+ LL LG VI+AL +  +  
Sbjct: 227 DKNSSFRS--KLHLVDLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGG 284

Query: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
            VPYR+SKLTR+LQDSLGG + T +IA +SPA  NLEETL+TL YA RA+ I NKP VN 
Sbjct: 285 FVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVN- 343

Query: 368 KLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQ-EEQIVELIEKI 426
                  I   T E+  LK+ +    ++  V + + +   + G +TV+  E +  L+EK 
Sbjct: 344 -------IDPQTAELNHLKQQV----QQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKN 392

Query: 427 GAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALE 486
            ++ EE  +++    +   +  Q    +    Q  E     L+E +     +  +   +E
Sbjct: 393 QSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVE 452

Query: 487 STE-EKLHDAASKLLNTVEETT----KDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSL 541
           + E ++L +    + N  +  T    + V+ + + +D   AV+Q             +  
Sbjct: 453 TLEDQELKENVEIICNLQQLITQLSDETVACMAAAID--TAVEQEAQVETSPETSRSSDA 510

Query: 542 FNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLT-SIPENVSTHV 600
           F     L +   SK+  ++E++K L    L  +++   T     L  +     +N+    
Sbjct: 511 FTTQHALRQAQMSKE--LVELNKAL---ALKEALARKMTQNDSQLQPIQYQYQDNIKELE 565

Query: 601 SQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKT 660
            ++ N+  +++ L  E +T  ++      ++        L   +  + K  ++   + K 
Sbjct: 566 LEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLLKL 625

Query: 661 SLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQ 720
             +    +    +E+    +     + +++E+        QK+   + + LK   +    
Sbjct: 626 KESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQ-LKERDRKRQY 684

Query: 721 ELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFS 780
           EL KL   + ++   L  K E        +++ + QK +++ +K     +      +G +
Sbjct: 685 ELLKLERNFQKQSNVLRRKTEEAAAANKRLKDAL-QKQREVADK---RKETQSRGMEGTA 740

Query: 781 QELRNFNQEGTKLV---EESVKHSDKLNGNLEKISQETEQRCE----------SLNTRTV 827
             ++N+     +++   EE+ +H + L  + + ++Q+  Q  E           L  RT 
Sbjct: 741 ARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTF 800

Query: 828 YFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKS----DGRKAAHEKQHNIFLDQ 883
             +E     ++E E  +   +E +    E  S+ I +      D       KQ   + + 
Sbjct: 801 SLTEV-RGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESEDRPKQR--WENI 857

Query: 884 MTIDEDKLIAQNLELNETI--KIGLTKLNCFLEQDLK--LDIPTGTTPQRKSYLYPST-- 937
            TI E K   + L + E +  KI ++KL   L+Q      D+      +R  +    T  
Sbjct: 858 ATILEAKCALKYL-IGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETEL 916

Query: 938 ---LVRTEPRE-----HLLDQLKR--------------KQPELLMMLNCSENNKEE 971
              LVR E +      +LL QL++              K+ +LL  L C +   E+
Sbjct: 917 QAELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEK 972


>gi|4758648 kinesin family member 5B [Homo sapiens]
          Length = 963

 Score =  267 bits (683), Expect = 3e-71
 Identities = 246/909 (27%), Positives = 411/909 (45%), Gaps = 88/909 (9%)

Query: 18  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTK 77
           NI+V+ R RP N +E               K ++   G      + K Y FD VF +ST 
Sbjct: 8   NIKVMCRFRPLNESEVNRGD----------KYIAKFQGEDTVVIASKPYAFDRVFQSSTS 57

Query: 78  QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP 137
           Q  VY      I+ +V+ GYN TIFAYGQT +GKT TMEG+    E          GIIP
Sbjct: 58  QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGM--------GIIP 109

Query: 138 RTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVI 195
           R +  IF  +   D   EF +KVS  EIY +++ DLL    DVS+      + +N R   
Sbjct: 110 RIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLL----DVSKTNLSVHEDKN-RVPY 164

Query: 196 IKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEEL 255
           +KG  E  V + DEV   +++G + R  A T MN +SSRSHS+F + +  + T  + +  
Sbjct: 165 VKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK-- 222

Query: 256 VKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESK 315
              GKL LVDLAGSE + ++GA      EA NIN+SL  LG VI+AL E + +VPYR+SK
Sbjct: 223 -LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSK 281

Query: 316 LTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALI 375
           +TRILQDSLGG  RT+I+   SP+S N  ET STL +  RAK I N   VN +LT +   
Sbjct: 282 MTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWK 341

Query: 376 KEYTEEIER----------LKRDLAAAREKNGVYISEENFR--------VMSGKLTVQEE 417
           K+Y +E E+          L+ +L   R    V I E+  +         +   +T+  +
Sbjct: 342 KKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTND 401

Query: 418 QIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVK 477
           +    I  IG   +   R  E       E+ +    L +K +E+    + +++ K Q++ 
Sbjct: 402 KPATAIGVIGNFTDAERRKCE------EEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLD 455

Query: 478 EEYITSALESTEEKLHDAASKL-------LNTVEETTKDVSGLHSKLDRKKAVDQHNAEA 530
           +E + ++    ++ +    ++L          V+E  + +  L    D+K    +   + 
Sbjct: 456 QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515

Query: 531 QDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLT 590
            ++    LN     +  +  +   K K M    K     +++S +  L  I      +  
Sbjct: 516 YELLSDELNQKSATLASIDAE-LQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDV 574

Query: 591 SIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKI 650
             PE       +     L    + +E KT+++    +  T   S+ +M  +   ++  ++
Sbjct: 575 KQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQL 634

Query: 651 N-SQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTE 709
             SQ +   K+       +E +K++L+  +  L   L +L+      + E +K+  N  +
Sbjct: 635 RISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQE--KVHEMEKEHLNKVQ 692

Query: 710 DLKTIKQTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHS 769
               +KQ   Q+              ++   E  QK +SS+++ ++ K+K ++  +   +
Sbjct: 693 TANEVKQAVEQQ--------------IQSHRETHQKQISSLRDEVEAKAK-LITDLQDQN 737

Query: 770 QKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYF 829
           QK   + +           E  KL     + S KL+  L  +    EQ  + L       
Sbjct: 738 QKMMLEQE-------RLRVEHEKLKATDQEKSRKLH-ELTVMQDRREQARQDLKGLEETV 789

Query: 830 SEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDED 889
           +++  +  N R+  + +L   V +  E  S D    +  ++     ++N  L+Q+T    
Sbjct: 790 AKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENN--LEQLTKVHK 847

Query: 890 KLIAQNLEL 898
           +L+  N +L
Sbjct: 848 QLVRDNADL 856


>gi|9910266 kinesin family member 15 [Homo sapiens]
          Length = 1388

 Score =  261 bits (666), Expect = 3e-69
 Identities = 320/1215 (26%), Positives = 529/1215 (43%), Gaps = 214/1215 (17%)

Query: 1    MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVE-CDPVRKEVSVRTGGLAD 59
            + S  N  + +   +G  I+V VR RP   AER  SA      C  V    S+R   L  
Sbjct: 9    LRSVTNGQSNQPSNEGDAIKVFVRIRP--PAERSGSADGEQNLCLSVLSSTSLR---LHS 63

Query: 60   KSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGER 119
                KT+TFD V    T Q  V+ +V   I++  + GYN TIFAYGQTG+GKTFTM G  
Sbjct: 64   NPEPKTFTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMG-- 121

Query: 120  SPNEEYTWEEDPLAGIIPRTLHQIFEKLTDN------GTEFSVKVSLLEIYNEELFDLLN 173
             P+E   +  + L G+IPR+   +F  +         G  F  K S +EIYNE+++DLL+
Sbjct: 122  -PSESDNFSHN-LRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLD 179

Query: 174  PSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSS 233
             +S       ++     K+GV + G  E  V +  E YQ+L  G   R  A+T MN  SS
Sbjct: 180  SAS-----AGLYLREHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESS 234

Query: 234  RSHSVFSVTIHMKETTIDGEELVKI--GKLNLVDLAGSENIGRSGAVDKRAREAGNINQS 291
            RSH+VF++TI   E +    E+V I    LNLVDLAGSE    + A   R +EAGNIN+S
Sbjct: 235  RSHAVFTITIESMEKS---NEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRS 291

Query: 292  LLTLGRVITALVE----RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETL 347
            L  LG+VITALV+    +  HV YR+SKLT +L+DSLGG  +T+IIA + P S    ETL
Sbjct: 292  LSCLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETL 351

Query: 348  STLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRV 407
            STL +A RAK I NK  VN+    +  + +   E++RLK  LA   E        E+F  
Sbjct: 352  STLNFAQRAKLIKNKAVVNE--DTQGNVSQLQAEVKRLKEQLA---ELASGQTPPESFLT 406

Query: 408  MSGKLT--------------VQEEQIVELIEKIGAVEEELNRVTELFMDNK--------- 444
               K T                E++   LIEK+  +E+   +  +    NK         
Sbjct: 407  RDKKKTNYMEYFQEAMLFFKKSEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQ 466

Query: 445  -----------------NELDQCKSDLQNKTQELETTQKH-------------LQETKLQ 474
                              E D+  S+L+N+ Q L    +H             L+E   +
Sbjct: 467  IIRLEKLHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRR 526

Query: 475  LVKEEYITSALE---STEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQ 531
            L   E +  A E    T  KL  A S+ ++ +E++ K+  G   K  ++  +  +  + +
Sbjct: 527  LRLLEPVKRAQEMDAQTIAKLEKAFSE-ISGMEKSDKNQQGFSPKAQKEPCLFANTEKLK 585

Query: 532  DIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTL---------FGNLLSSS-------V 575
                +    L N+ +E  +     +K  LE+   L           NLL ++       V
Sbjct: 586  AQLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQEV 645

Query: 576  SALDTITTVALGSLTSIPENVSTH---------------------VSQIFNMILKE---- 610
            S L+ I    L  +T+  +    H                      S + N IL E    
Sbjct: 646  SQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPP 705

Query: 611  -------QSLAAESKTVLQELINVL--KTDLLSSLEMILSPTVVSILKINSQLKHIFKTS 661
                   ++++ E +TV QE ++ L  K D      + L   V  +   ++Q++ +F + 
Sbjct: 706  EMNEQAFEAISEELRTV-QEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSE 764

Query: 662  -----------LTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTED 710
                       L+  + +E Q +E       L + +H+L+      L  + K+  ++  +
Sbjct: 765  RIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLR----VVLHSADKELSSVKLE 820

Query: 711  LKTIKQTHSQELCKL------MNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNK 764
              + K    +E  KL      + L  +      EK    +  L    +N+Q+  K  +++
Sbjct: 821  YSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQ 880

Query: 765  MTFHSQKFCADSDGFSQELRNF-----------NQEGTKLVEESVKHSDKLNGNLEKISQ 813
            ++ + Q F  +++    +L N            N+   +  E+    S ++   LE + Q
Sbjct: 881  LSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQ 940

Query: 814  ETEQ---RCESLNTR------TVYFSEQWVSSLNEREQE--------LHNLLEVVSQCCE 856
            E ++   +CE    +      ++  +E+ +SSL +            ++ + E+ +  CE
Sbjct: 941  EKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCE 1000

Query: 857  ASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQN-----LELNETIKIGLTKLNC 911
             + +  T K +  K  + K ++  +D+   +E +++ +      L+L ET+++ +  L+ 
Sbjct: 1001 KTETIDTLKQE-LKDINCKYNSALVDR---EESRVLIKKQEVDILDLKETLRLRI--LSE 1054

Query: 912  FLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLMMLNCSENNKEE 971
             +E+D+  +     T Q  + L  ++   +   +   ++L +K+  L+  L    N K+E
Sbjct: 1055 DIERDMLCEDLAHATEQ-LNMLTEASKKHSGLLQSAQEELTKKE-ALIQELQHKLNQKKE 1112

Query: 972  TIPDVDVEEAVLGQYTEEPLSQEPSVD-AGVDCSSIGGVPFFQHKKSHGKDKENRGINTL 1030
             +      E    +Y  +    E  +D A  D  S    P FQ   +   + + + I   
Sbjct: 1113 EV------EQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDG 1166

Query: 1031 ERSKVEETTEHLVTK 1045
              SK   + EHLVTK
Sbjct: 1167 RASKT--SLEHLVTK 1179



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 133/639 (20%), Positives = 246/639 (38%), Gaps = 111/639 (17%)

Query: 344  EETLSTLEYAHR------AKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAR---E 394
            EE LS L    +       KN   K EV+     + ++    +E+  +K + ++ +   E
Sbjct: 773  EELLSQLNVLEKQLQETQTKNDFLKSEVHDL---RVVLHSADKELSSVKLEYSSFKTNQE 829

Query: 395  KNGVYISEENFRVMS--GKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKS 452
            K    +SE +  V      L ++ E+   L+E    +++  + + E+    K E+DQ   
Sbjct: 830  KEFNKLSERHMHVQLQLDNLRLENEK---LLESKACLQDSYDNLQEIM---KFEIDQLSR 883

Query: 453  DLQNKTQELETTQKHLQETK--LQLVKEEYITSALESTEEKLHDAASKLLNTVE------ 504
            +LQN  +E ET +  L      L+  KE     +L+  E+K  +++ ++L  +E      
Sbjct: 884  NLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEEDK-ENSSKEILKVLEAVRQEK 942

Query: 505  --ETTK------DVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL-------- 548
              ET K       V  L   L   + V     +++D   K +  L N ++EL        
Sbjct: 943  QKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKT 1002

Query: 549  ---------IKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVS-- 597
                     +KD + K  + L   +     +    V  LD   T+ L  L+   E     
Sbjct: 1003 ETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLC 1062

Query: 598  ---THVSQIFNMILKEQ-------SLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSI 647
                H ++  NM+ +           A E  T  + LI  L+  L    E +        
Sbjct: 1063 EDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYN 1122

Query: 648  LKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNL 707
             K+  QL+H+  ++       + Q  +           L E QE  I     S+    +L
Sbjct: 1123 FKMR-QLEHVMDSAAE-----DPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHL 1176

Query: 708  TEDLKTIKQTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQEN--IQQKSKDIVNKM 765
               L   ++  + E+ ++     E         EN++     + E   + Q   D + + 
Sbjct: 1177 VTKLNEDREVKNAEILRMKEQLRE--------MENLRLESQQLIEKNWLLQGQLDDIKRQ 1228

Query: 766  TFHSQKFCADSDGFSQELRNFNQEG-------TKLVEESVK--------HSDKLNGNLEK 810
              +S +   D    +Q+L+N  +E        +K+VEE +K         S   N  +E 
Sbjct: 1229 KENSDQNHPD----NQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMEC 1284

Query: 811  ISQETE-QRCESLNTRTVYFSEQWVSSLNEREQELHNL---LEVVSQCCEASSSDITEKS 866
            +    E +R ++L ++     EQ  S L E  +E       +E++ +  E  + +   K 
Sbjct: 1285 LRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEE-NGKL 1343

Query: 867  DGRKAAHEK-QHNIFLDQMTI----DEDKLIAQNLELNE 900
             G +  H+K Q+ + L +  +    + +KL A+N+ L E
Sbjct: 1344 VGHQNLHQKIQYVVRLKKENVRLAEETEKLRAENVFLKE 1382


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score =  257 bits (657), Expect = 4e-68
 Identities = 260/937 (27%), Positives = 422/937 (45%), Gaps = 104/937 (11%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
           + V VR RP N  E      S+ E   V  +         D S  K++ FD VF  +   
Sbjct: 7   VAVCVRVRPLNSREE-----SLGETAQVYWKTDNNVIYQVDGS--KSFNFDRVFHGNETT 59

Query: 79  IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
            +VY  +  PI+D  I GYN TIFAYGQT +GKT+TM G           ED L G+IPR
Sbjct: 60  KNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMG----------SEDHL-GVIPR 108

Query: 139 TLHQIFEKLTD-NGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIK 197
            +H IF+K+      EF ++VS +EIYNE + DLL  +  +   +   D  RN   V + 
Sbjct: 109 AIHDIFQKIKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRN---VYVA 165

Query: 198 GLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKE--TTIDGEEL 255
            L E  V+  +   + + KG   R    T MN  SSRSH++F + +  +E     + E  
Sbjct: 166 DLTEEVVYTSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGS 225

Query: 256 VKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERT--PHVPYRE 313
           VK+  LNLVDLAGSE   ++GA   R +E  NIN+SL  LG+VI  L +      + YR+
Sbjct: 226 VKVSHLNLVDLAGSERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRD 285

Query: 314 SKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKA 373
           SKLTRILQ+SLGG  +T II TI+P S   +ETL+ L++A  AK + N P VN+  T +A
Sbjct: 286 SKLTRILQNSLGGNAKTRIICTITPVS--FDETLTALQFASTAKYMKNTPYVNEVSTDEA 343

Query: 374 LIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEEL 433
           L+K Y +EI  LK+ L             E   + +    ++++Q+ +L+E+    ++ L
Sbjct: 344 LLKRYRKEIMDLKKQL-------------EEVSLETRAQAMEKDQLAQLLEE----KDLL 386

Query: 434 NRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQE---TKLQLVKEEYITSALE---S 487
            +V    ++N   +    S L    QEL+  +K        K+  +K            +
Sbjct: 387 QKVQNEKIENLTRMLVTSSSL-TLQQELKAKRKRRVTWCLGKINKMKNSNYADQFNIPTN 445

Query: 488 TEEKLHDAASKLLNTVEETTKDVSGLHSK-LDRKKAVDQHNAEA---QDIFGKNLNSLFN 543
              K H  +  LL  ++E+    S + S  LD    ++ + A     Q+     LNSL  
Sbjct: 446 ITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSLRA 505

Query: 544 NMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTV--------ALGSLTSIPEN 595
           + + L+ D    +    E+   L          AL+  T           + +L ++ ++
Sbjct: 506 DYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKH 565

Query: 596 VSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLK 655
              +   + N +  +  L  E +  +++L   + +  L +++M LS ++ SI       +
Sbjct: 566 AEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQ 625

Query: 656 HIFKTSLTVADK------IEDQKKELDGFLSILCNNLHELQENTICSLVESQKQC-GNLT 708
            +F       D       +  +  EL   +  L     ++ EN I  L +SQ +    + 
Sbjct: 626 TLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQM-ENDI-QLYQSQLEAKKKMQ 683

Query: 709 EDLKTIKQTHSQELCKLMNLWTERF-------CALEEKCENIQKPLS-SVQENIQQKSKD 760
            DL+   Q+   E+ KL +L   +          LE K  ++QK L+  V+EN   + + 
Sbjct: 684 VDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEV 743

Query: 761 I----VNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKIS---- 812
           I    +  +    ++   +    S+EL     E  KL  E V    ++ G LE+I     
Sbjct: 744 ILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKD 803

Query: 813 ---------QETEQRCESLNTRTVYFSEQWVSSLNERE---QELHNLLEVVSQCCEASSS 860
                    + T+Q  ++  T  + F +++   L E E   QE+ NL +   +   +  +
Sbjct: 804 DLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGA 863

Query: 861 DITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLE 897
             TE S   +   EK   +   Q  ++E + + + LE
Sbjct: 864 LKTELSYKTQELQEKTREV---QERLNEMEQLKEQLE 897



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 172/941 (18%), Positives = 369/941 (39%), Gaps = 122/941 (12%)

Query: 149  DNGTEFSVKVSLLEIYNEELFDLL---------NPSSDVSERLQMFDDPRNKRGVIIKGL 199
            D   E S KV LL    +++  L          N   D+S  L+  +DP+  +  +    
Sbjct: 572  DLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDA- 630

Query: 200  EEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIG 259
            E + +  K E   +  +    +     L   Y    +      I + ++ ++ ++ +++ 
Sbjct: 631  ETVALDAKRESAFLRSENLELKEKMKELATTYKQMEND-----IQLYQSQLEAKKKMQVD 685

Query: 260  KLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRI 319
                +  A +E    +  +D      G + + LL         +E    +   + +L + 
Sbjct: 686  LEKELQSAFNEITKLTSLID------GKVPKDLL-------CNLELEGKITDLQKELNKE 732

Query: 320  LQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPE---VNQKLTKKALIK 376
            ++++   R    +++ +      +E     ++      +I+   +    ++ + K++ ++
Sbjct: 733  VEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQ 792

Query: 377  EYTEEIERLKRDLAAAREKNGVYISE-ENFRVMSGKLTVQEEQIVELIEKIGAVEEELNR 435
               EEI + K DLA  +        E +NF+ +      + + ++E  E++      L++
Sbjct: 793  GLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSK 852

Query: 436  VTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDA 495
              + F    + L   K++L  KTQEL+   + +QE            + +E  +E+L + 
Sbjct: 853  EAQKF---DSSLGALKTELSYKTQELQEKTREVQER----------LNEMEQLKEQLENR 899

Query: 496  ASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSK 555
             S L     E T     L   L+  K + Q   + + +      SL    ++L  D    
Sbjct: 900  DSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQL----QESLQIERDQLKSDIHDT 955

Query: 556  QKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAA 615
                ++  + L  N L S     +TI T+     + I E VS       N+ ++E +   
Sbjct: 956  VNMNIDTQEQL-RNALESLKQHQETINTLK----SKISEEVSR------NLHMEENT--G 1002

Query: 616  ESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKEL 675
            E+K   Q+   ++  D    LE   + T+ + +K N  ++   K    + +K E Q+  L
Sbjct: 1003 ETKDEFQQ--KMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQM-L 1059

Query: 676  DGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWTE--RF 733
            +  ++       +L+EN I   +E+Q++   L ++LK  ++  +QE    +    E  R 
Sbjct: 1060 ESVIAEKEQLKTDLKEN-IEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRT 1118

Query: 734  CALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHS--QKFCADSDGFSQELRNFNQEGT 791
            C   ++   +++ L    + +Q+K + ++N     S  QK   + +    EL+N      
Sbjct: 1119 C---DRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLE 1175

Query: 792  KLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQ-----WVSSLNEREQELHN 846
             +  E ++ + KLN N E++   T++R      +  + +E+     ++  +     +   
Sbjct: 1176 HMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKE 1235

Query: 847  LLEVVSQCCEASSSDITE--KSDGRKAAH-------EKQHNIFLDQMTI--DEDKLIAQN 895
             L++     +     I E  +S   K A        EK H    +++ +  +E +L+   
Sbjct: 1236 ELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQELLPNV 1295

Query: 896  LELNETIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQ 955
             E++ET +  + +L    EQ    D               +TL R E     L++  ++ 
Sbjct: 1296 KEVSETQET-MNELELLTEQSTTKD--------------STTLARIEMERLRLNEKFQES 1340

Query: 956  PELLMMLNCSENNKEETIPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHK 1015
             E +  L    +N +     ++V+   L ++  E L++     +             Q +
Sbjct: 1341 QEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSK------------QEQ 1388

Query: 1016 KSHGKDKENRGINTLERSKVEETTEHLVTKSRLPLRAQINL 1056
              + K+K+N      E +K+    E    K    LR +I +
Sbjct: 1389 SLNMKEKDN------ETTKIVSEMEQFKPKDSALLRIEIEM 1423



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 188/993 (18%), Positives = 381/993 (38%), Gaps = 170/993 (17%)

Query: 146  KLTDNGTEFSVKVSLLEIYNEE---LFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEI 202
            K+TD   E + +V   E   EE   L +L +  S+V    +   D   +  +I    +++
Sbjct: 721  KITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKL 780

Query: 203  ---TVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSV-TIHM----------KET 248
                VH +  V  +LE+    +   AT  + Y S      +  T+HM          +E 
Sbjct: 781  FSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEEN 840

Query: 249  TIDGEELVKIGKL-----NLVDLAGSENIGRSGAVDKRAREAG--------------NIN 289
                +E+V + K      + +    +E   ++  + ++ RE                N +
Sbjct: 841  ERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRD 900

Query: 290  QSLLTLGRVITALVERTPHVPYRESKLT------RILQDSLG---GRTRTSIIATISPAS 340
             +L T+ R  T + E+          LT      + LQ+SL     + ++ I  T++   
Sbjct: 901  STLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNI 960

Query: 341  LNLEETLSTLEYAHRAKNILN--KPEVNQKLTKKALIKEYTEEI-ERLKRDLAAAREKNG 397
               E+  + LE   + +  +N  K ++++++++   ++E T E  +  ++ +    +K  
Sbjct: 961  DTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQD 1020

Query: 398  VYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNK 457
              +  +N + ++    V++ +I+E   KI ++ +E N + ++      E +Q K+DL+  
Sbjct: 1021 --LEAKNTQTLTAD--VKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKEN 1076

Query: 458  TQ--------------ELETTQKHLQETKLQLVKEE-----------YITSALESTEEKL 492
             +              EL+  Q+ + + K   +K+E            +   L+   ++L
Sbjct: 1077 IEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQL 1136

Query: 493  HDAASKLLNTVEETTK------DVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNME 546
             +   +LLN  EE ++      ++  L ++L  K+   +H    +    + LN    N E
Sbjct: 1137 QEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLN---ENYE 1193

Query: 547  ELIKDGSSKQKAMLEVHKT-------LFGNLLSSSVSALDT-----ITTVALGSLTSIPE 594
            E +K  + ++K + E+ K+       L G +     + L T     I  + L       +
Sbjct: 1194 E-VKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETID 1252

Query: 595  NVSTHVSQIFNMILKEQSLAAESKTVLQELINVL--KTDLLSSLEMILSP---------- 642
             +   VS+    I+  Q L  +S T LQE I VL  + +LL +++ +             
Sbjct: 1253 ELRRSVSEKTAQIINTQDL-EKSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELL 1311

Query: 643  TVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGF-------------LSILCNNLHEL 689
            T  S  K ++ L  I    L + +K ++ ++E+                L +  + L E 
Sbjct: 1312 TEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEH 1371

Query: 690  QENTICSLVES---QKQCGNLTE-DLKTIKQTHSQELCK-------------------LM 726
               T+  + ES   Q+Q  N+ E D +T K     E  K                   L 
Sbjct: 1372 IRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQ 1431

Query: 727  NLWTERFCALEEK--CENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELR 784
                E     +EK   + +Q+ L S  + +++  K+IV K     ++         ++  
Sbjct: 1432 ESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEE 1491

Query: 785  NFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQEL 844
              N+    L E+  + S  +   LE I+ + + + + +  +   F+ + +S + E+  EL
Sbjct: 1492 TINELRVNLSEKETEIS-TIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNEL 1550

Query: 845  HNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKI 904
                E       A  S  ++  +      E Q  I +     +E K + + L++      
Sbjct: 1551 KQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERD--- 1607

Query: 905  GLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLMMLNC 964
                    L+++ K  +      Q K Y +       E +E + +    K+      LN 
Sbjct: 1608 -------QLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLN- 1659

Query: 965  SENNKEETIPDVDVEEAVLGQYTEEPLSQEPSV 997
                    + +++ E   L Q   E L +  SV
Sbjct: 1660 --------LENIETENIRLTQILHENLEEMRSV 1684



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 108/543 (19%), Positives = 234/543 (43%), Gaps = 66/543 (12%)

Query: 304  ERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKP 363
            E++ ++  ++++ T+I+ +    + + S +  I    L L + L   E     K++  + 
Sbjct: 1387 EQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQ--ESHDEMKSVAKEK 1444

Query: 364  EVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELI 423
            +  Q+L ++ L  E  +  E +K  +A   E      +EE  +V    L  QEE I EL 
Sbjct: 1445 DDLQRL-QEVLQSESDQLKENIKEIVAKHLE------TEEELKVAHCCLKEQEETINELR 1497

Query: 424  EKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYIT- 482
              +   E E++ +       + +L+     LQNK QE+   ++     ++  V+E+    
Sbjct: 1498 VNLSEKETEISTI-------QKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNEL 1550

Query: 483  -----------SALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAEAQ 531
                       SAL+S E K+ +    L N ++E+ +++  +  + +  K V       Q
Sbjct: 1551 KQFKEHRKAKDSALQSIESKMLE----LTNRLQESQEEIQIMIKEKEEMKRV-------Q 1599

Query: 532  DIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTS 591
            +      + L  N +E++      Q+   +  K    N     +  ++ +         +
Sbjct: 1600 EALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLN 1659

Query: 592  IPENVSTH---VSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSIL 648
            + EN+ T    ++QI +  L+E     + +  L+ +   LK +    L+  L  T+   L
Sbjct: 1660 L-ENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVER-DQLKENLRETITRDL 1717

Query: 649  KINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLT 708
            +   +LK +        + I+    +L G +S   N +  +Q++   S    + Q   + 
Sbjct: 1718 EKQEELKIVHMHLKEHQETID----KLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQ 1773

Query: 709  EDLKTIKQTHSQE----LCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDI--- 761
            E+L+ I   H +E    + KL  + +E+     +K  N+QK L +    +Q+K +++   
Sbjct: 1774 EELR-IAHMHLKEQQETIDKLRGIVSEK----TDKLSNMQKDLENSNAKLQEKIQELKAN 1828

Query: 762  ------VNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQET 815
                  + K    +QK  ++ +   +++++ +   +KL  E++  + KL+ NLE++    
Sbjct: 1829 EHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVM 1888

Query: 816  EQR 818
            ++R
Sbjct: 1889 KER 1891



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 160/866 (18%), Positives = 339/866 (39%), Gaps = 87/866 (10%)

Query: 158  VSLLEIYNEELFDLLNPSSD------VSERLQMFDDP--RNKRGVIIKGLEE------IT 203
            + L +I +E L ++ + + +      V E L++  D    N R  I + LE+      + 
Sbjct: 1668 IRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVH 1727

Query: 204  VHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNL 263
            +H K+    I +           + N      HS  +    +K   +  +E ++I  ++L
Sbjct: 1728 MHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDA----LKAQDLKIQEELRIAHMHL 1783

Query: 264  VDLAGSENIGR-SGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQD 322
             +    E I +  G V ++  +  N+ + L         L E+   +   E +L  + +D
Sbjct: 1784 KEQ--QETIDKLRGIVSEKTDKLSNMQKDLENSN---AKLQEKIQELKANEHQLITLKKD 1838

Query: 323  SLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEI 382
                + + S +  +     +   TLS LE     +N+    ++++ L +   + +  + +
Sbjct: 1839 VNETQKKVSEMEQLKKQIKDQSLTLSKLEI----ENLNLAQKLHENLEEMKSVMKERDNL 1894

Query: 383  ERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIV--ELIEKIGAVEEELNRVTELF 440
             R++  L   R++    + E   R +  +  ++  +++  E  E +  + E+++  T   
Sbjct: 1895 RRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQI 1954

Query: 441  MDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLL 500
             D + +LD+ K +LQ K QEL+  +  L   K  +       + +E  +++       + 
Sbjct: 1955 SDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLSMQ 2014

Query: 501  NTVEETTKDVSGLHSKLDRKKAVDQHNAEAQDI---FGKNLNSLFNNMEELIKDGSSKQK 557
            +   +  +    LH  L+  + V +   E + I        +     + E+I     +Q 
Sbjct: 2015 SVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMI--ARDRQN 2072

Query: 558  AMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFN--MILKEQSLAA 615
              ++  K     LLS     L    T +L    S  + +    S++ +    L   SL  
Sbjct: 2073 HQVKPEK----RLLSDGQQHL----TESLREKCSRIKELLKRYSEMDDHYECLNRLSLDL 2124

Query: 616  ESKTVLQ-ELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIF-------KTSLTVADK 667
            E +   Q EL   +K +L  SL  + +  +  +   N +    F       K  L+   K
Sbjct: 2125 EKEIEFQKELSMRVKANL--SLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTK 2182

Query: 668  IEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIK-----QTHSQEL 722
            I++++ E      +   +  E Q+  +  +   Q+ C   + +L+ +K       H +E+
Sbjct: 2183 IKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEI 2242

Query: 723  CKLMNLWTERFCALEEKCENI---QKPLSSVQE---NIQQKSKDIVNKMTFHSQKFCADS 776
             K  +     F +++ + + +   +K ++   E   N +   + + N +   + + C  +
Sbjct: 2243 LK--DFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVN 2300

Query: 777  DGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNT-RTVYFSEQWVS 835
            + F+  +     E T+  E S   S +   +L+ + ++ E+  ++  T +T   S   V+
Sbjct: 2301 NFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVN 2360

Query: 836  SLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQN 895
               +  +  H    V S+  + ++  I E  +    A E   +         E K+I   
Sbjct: 2361 PTTQDNKNPH----VTSRATQLTTEKIRELENSLHEAKESAMH--------KESKIIKMQ 2408

Query: 896  LELNETIKIGLTKLNCFLEQDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRK- 954
             EL  T  I + KL   + +  K    T  T Q    L     +  +P +  ++ LK K 
Sbjct: 2409 KELEVTNDI-IAKLQAKVHESNKCLEKTKETIQ---VLQDKVALGAKPYKEEIEDLKMKL 2464

Query: 955  -QPELLMMLNCSENNKEETIPDVDVE 979
             + +L  M N  E  KE +     VE
Sbjct: 2465 VKIDLEKMKNAKEFEKEISATKATVE 2490



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 38/189 (20%), Positives = 78/189 (41%), Gaps = 2/189 (1%)

Query: 351  EYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSG 410
            E+  R+  I  + E + K  K+   K + +  + LK  LA+  + N      +N  V S 
Sbjct: 2316 EFEERSATISKEWEQDLKSLKEKNEKLF-KNYQTLKTSLASGAQVNPTTQDNKNPHVTSR 2374

Query: 411  KLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQE 470
               +  E+I EL   +   +E         +  + EL+     +     ++  + K L++
Sbjct: 2375 ATQLTTEKIRELENSLHEAKESAMHKESKIIKMQKELEVTNDIIAKLQAKVHESNKCLEK 2434

Query: 471  TKLQL-VKEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAVDQHNAE 529
            TK  + V ++ +    +  +E++ D   KL+    E  K+      ++   KA  ++  E
Sbjct: 2435 TKETIQVLQDKVALGAKPYKEEIEDLKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKE 2494

Query: 530  AQDIFGKNL 538
               +  +NL
Sbjct: 2495 VIRLLRENL 2503


>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
          Length = 1317

 Score =  257 bits (656), Expect = 5e-68
 Identities = 268/978 (27%), Positives = 454/978 (46%), Gaps = 115/978 (11%)

Query: 18  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVS---VRTGGLAD--KSSRKTYTFDMVF 72
           +++V VR RP N  E+   A  I++ +  +  ++   +  GG  D  +   KT+T+D  F
Sbjct: 3   SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62

Query: 73  -GASTKQID------VYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEY 125
             A TK  D      V++++   ++     GYN  +FAYGQTG+GK++TM G    +   
Sbjct: 63  YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119

Query: 126 TWEEDPLAGIIPRTLHQIFEKLTD----NGTEFSVKVSLLEIYNEELFDLLNPSSDVSER 181
                   G+IPR    +F ++ +    +   F  +VS LEIYNE + DLL   S  +  
Sbjct: 120 --------GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFN 171

Query: 182 LQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSV 241
           L++ + P  K G  ++ L +  V N  +V ++++ G   RTTAAT MN  SSRSH++F  
Sbjct: 172 LRVREHP--KEGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIF-- 227

Query: 242 TIHMKETTIDGEELVK-IGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
           TI   +   D E   + + K++LVDLAGSE    +GA   R +E GNIN+SL+TLG VI+
Sbjct: 228 TIKFTQAKFDSEMPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVIS 287

Query: 301 ALVE------------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLS 348
           AL +            +   VPYR+S LT +L+DSLGG ++T +IATISPA +N  ETLS
Sbjct: 288 ALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLS 347

Query: 349 TLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVM 408
           TL YA+RAKNI+NKP +N+    K LI+E   EI RLK  LA   +     +       M
Sbjct: 348 TLRYANRAKNIINKPTINEDANVK-LIRELRAEIARLKTLLAQGNQI--ALLDSPTALSM 404

Query: 409 SGKLTVQEEQIVELI-EKIGAVEEELNRVTELFMDNKNE-----LDQCKSDLQNKTQELE 462
             KL   E ++ EL  E      E  N + E  +  + E     LD     L     +L 
Sbjct: 405 EEKLQQNEARVQELTKEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLL 464

Query: 463 TT---QKHLQETKLQLVKEEYITS---ALESTE-EKLHDAASKLLNTVEETTKDVSGLHS 515
           +T     HL+E +  + +++  T     L   + E  H     +  TV  T   +SG   
Sbjct: 465 STGIILYHLKEGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTV--TLIPLSGSQC 522

Query: 516 KLDRKKAVD--QHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSS 573
            ++  + V+    N  A  + G+     FN+ +E  K        + E  K+  G L S 
Sbjct: 523 SVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAAK--------LREKRKS--GLLSSF 572

Query: 574 SVSALDTITTVALGSLTSIPENVST----HVSQIFNMILKEQSLAAESK-TVLQELINVL 628
           S+S  D         L+   EN+S     +    F    +E+    ESK  +++E+    
Sbjct: 573 SLSMTD---------LSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQ 623

Query: 629 KTD------LLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSIL 682
           K+D      +   +E     T +  L+I  Q + + + S  + +K++D   E + F    
Sbjct: 624 KSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEE-- 681

Query: 683 CNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKCEN 742
              L E QE  +    + ++    + E+L+ +K+ ++ E  +   ++ E     +EK E 
Sbjct: 682 -ERLREQQEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQ 740

Query: 743 IQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSD 802
             K L   ++ ++++ K+ V  +  H ++   +     Q LR   +   + VEE  +  +
Sbjct: 741 YAK-LELEKKRLEEQEKEQV-MLVAHLEEQLREKQEMIQLLR---RGEVQWVEEEKRDLE 795

Query: 803 KLNGNLEKISQ------ETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCE 856
            +  +L ++ +      E  +  E    R   F  + +  L   E++L    +++ +   
Sbjct: 796 GIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKK--- 852

Query: 857 ASSSDITEKSDGRKAAHEKQHNIF--LDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLE 914
               +  E  +  K  H+K+  +    D+   D  + + Q+ E  + ++  L      L+
Sbjct: 853 -EVQEEQEILECLKCEHDKESRLLEKHDESVTDVTE-VPQDFEKIKPVEYRLQYKERQLQ 910

Query: 915 QDLKLDIPTGTTPQRKSY 932
             L+  +PT    +++++
Sbjct: 911 YLLQNHLPTLLEEKQRAF 928



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 114/571 (19%), Positives = 229/571 (40%), Gaps = 75/571 (13%)

Query: 375  IKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELN 434
            +K  +  IE   +DL A +EK      EE  R    ++ +Q+++  E  E    V+EEL 
Sbjct: 658  LKRRSFHIENKLKDLLAEKEK----FEEERLREQQ-EIELQKKRQEE--ETFLRVQEELQ 710

Query: 435  RVTELFMDNK-------NELDQCKSDLQNKTQELETTQKHLQE-TKLQLVKEEYITSALE 486
            R+ EL  + K        ELDQ + +   +  +LE  +K L+E  K Q++   ++   L 
Sbjct: 711  RLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLR 770

Query: 487  STEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKAV----DQHNAEAQ-------DIFG 535
              +E +       +  VEE  +D+ G+   L R K      D+   E +       +   
Sbjct: 771  EKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKR 830

Query: 536  KNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPEN 595
            + L  L N  ++L++     +K + E  + L    L         +      S+T +   
Sbjct: 831  RQLVKLVNLEKDLVQQKDILKKEVQEEQEIL--ECLKCEHDKESRLLEKHDESVTDV--- 885

Query: 596  VSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLK 655
              T V Q F  I   +      +  LQ L+      LL   +          L +++ L 
Sbjct: 886  --TEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLY 943

Query: 656  HIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQ---ENTICSLVESQKQCGNLTEDLK 712
             + K       ++E+++++L  +     N L +LQ   E T     + +K      E L+
Sbjct: 944  QVEK-------EMEEKEEQLAQY-QANANQLQKLQATFEFTANIARQEEKVRKKEKEILE 995

Query: 713  TIKQTHSQELCKLMNLWTERFCALEE------KCENIQKPLSSVQENIQQKSKDIVNKMT 766
            + ++   + L + +     R  AL+       + E  ++ L+S+    +++S  +   + 
Sbjct: 996  SREKQQREALERALARLERRHSALQRHSTLGMEIEEQRQKLASLNSGSREQS-GLQASLE 1054

Query: 767  FHSQKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEK----ISQETEQRCESL 822
               +    D +    E++   Q+  ++      H   L G +      +S E       +
Sbjct: 1055 AEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLM 1114

Query: 823  NTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLD 882
            + R   + E+      E ++ L +L  V+S+ C  S+  + +        +EK HN  + 
Sbjct: 1115 DARINAYIEE------EVQRRLQDLHRVISEGCSTSADTMKD--------NEKLHNGTI- 1159

Query: 883  QMTIDEDKLIAQNL-----ELNETIKIGLTK 908
            Q  +  +++++++L     +L + IKI + +
Sbjct: 1160 QRKLKYERMVSRSLGANPDDLKDPIKISIPR 1190


>gi|30794488 kinesin family member 27 [Homo sapiens]
          Length = 1401

 Score =  239 bits (609), Expect = 1e-62
 Identities = 274/1045 (26%), Positives = 481/1045 (46%), Gaps = 150/1045 (14%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
           ++V VR RP    E   +    V   P  ++V +           + +TFD VFG ++ Q
Sbjct: 6   VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVII--------GRDRVFTFDFVFGKNSTQ 57

Query: 79  IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
            +VY + + P++  +I GYN T+FAYGQTG+GKT+T+ G    +       +   GIIPR
Sbjct: 58  DEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVV-----EGQKGIIPR 112

Query: 139 TLHQIFEKLTDNGT-EFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIK 197
            + +IF+ ++++ + +F+VKVS +E+Y E+L DLL   + + + L + +D   K   +I 
Sbjct: 113 AIQEIFQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKD-LHIRED--EKGNTVIV 169

Query: 198 GLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVK 257
           G +E  V +  EV  +LE G A R T  T MN +SSRSH++F+++I      ++  E   
Sbjct: 170 GAKECHVESAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGS 229

Query: 258 -------IGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVE---RTP 307
                  + K + VDLAGSE + ++G   +R +E+  IN  LL LG VI+AL +   ++ 
Sbjct: 230 WYSPRHIVSKFHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSS 289

Query: 308 HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQ 367
           H+PYR++K+TR+L+DSLGG  +T +I  +SP+S N +E+L++L+YA+RA+NI NKP VN 
Sbjct: 290 HIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNF 349

Query: 368 KLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMS---GKLTVQEEQIVELI- 423
              +   I E   EI+ L+  L +  ++ GV  + +  R  S    ++   EEQ+ +L  
Sbjct: 350 S-PESDRIDEMEFEIKLLREALQS--QQAGVSQTTQINREGSPDTNRIHSLEEQVAQLQG 406

Query: 424 EKIG---AVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEY 480
           E +G    VEE    + +L                  T  L   Q+H  +    +++E  
Sbjct: 407 ECLGYQCCVEEAFTFLVDL----------------KDTVRLNEKQQHKLQEWFNMIQE-- 448

Query: 481 ITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKK-----AVDQHNAEAQDIFG 535
           +  A+ ++   +   AS     +EE  + V+ L  K + KK     A D+     +++  
Sbjct: 449 VRKAVLTSFRGIGGTAS-----LEEGPQHVTVLQLKRELKKCQCVLAADEVVFNQKELEV 503

Query: 536 KNLNSLFNNMEELIKDGSSKQKAMLEVHKT------------LFGNLLSSSVSALDTITT 583
           K L    N ++ ++++      ++ E  K             L  + LS  ++ L+   T
Sbjct: 504 KELK---NQVQMMVQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVT 560

Query: 584 VAL------GSLTSIPEN------VSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTD 631
            +       G    IPE         TH+     +  ++ S    +   +  L  +    
Sbjct: 561 SSAKENCGDGPDARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIF-AG 619

Query: 632 LLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQE 691
             +  +M+L         I  Q K +       +D  +D++ E        C +   +Q+
Sbjct: 620 FRTRSQMLLG-------HIEEQDKVL---HCQFSDNSDDEESEGQEKSGTRCRSRSWIQK 669

Query: 692 -NTICSLVE-----SQKQCGNL-TEDLKTIKQTHSQE--LCKLMN---LWTERFCALEEK 739
            +++CSLVE      + Q  +L  EDLK      SQE  L KL N   + TE    + E 
Sbjct: 670 PDSVCSLVELSDTQDETQKSDLENEDLKIDCLQESQELNLQKLKNSERILTEAKQKMREL 729

Query: 740 CENIQKPLSSVQENIQ--QKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEES 797
             NI+     ++E I+    +K +  + +    K   D++          Q   +L+E  
Sbjct: 730 TINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAE----------QAKVELIETQ 779

Query: 798 VKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCEA 857
            +  +  N +L  ++ + + + E    + +  ++  V  L +++Q+   L  +  Q  E 
Sbjct: 780 KQLQELENKDLSDVAMKVKLQKEF--RKKMDAAKLRVQVLQKKQQDSKKLASLSIQ-NEK 836

Query: 858 SSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLEQDL 917
            ++++ +  D     H K   I L +   +E++   +  +L+  IK    K+    E  L
Sbjct: 837 RANELEQSVD-----HMKYQKIQLQRKLREENE---KRKQLDAVIKRDQQKIK---EIQL 885

Query: 918 KLDIPTGTTPQRKSYLYPSTLVRTEPR----EHL--LDQLKRKQPELLMMLNCSENNKEE 971
           K     G  P+ +  L    L R +      +HL  LD+ K+   E +  +       EE
Sbjct: 886 KTGQEEGLKPKAED-LDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEE 944

Query: 972 TIPDVDVEEAVLGQYTEEPLSQEPS 996
              D+   EA++ +  +E L QE S
Sbjct: 945 LEADLKKREAIVSK--KEALLQEKS 967



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 89/417 (21%), Positives = 161/417 (38%), Gaps = 34/417 (8%)

Query: 451  KSDLQNKTQELETTQKHLQETKLQLVK--EEYITSALESTEEKLHDAASK--LLNTVEET 506
            KSDL+N+  +++  Q+  QE  LQ +K  E  +T A +   E   +   K  L+  + +T
Sbjct: 688  KSDLENEDLKIDCLQES-QELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKT 746

Query: 507  TKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL----IKDGSSKQKAMLEV 562
              D   +  +   K    +H+AE   +    L      ++EL    + D + K K   E 
Sbjct: 747  GNDAKSVSKQYSLKVTKLEHDAEQAKV---ELIETQKQLQELENKDLSDVAMKVKLQKEF 803

Query: 563  HKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMI----LKEQSLAAESK 618
             K +    L   V       +  L SL+   E  +  + Q  + +    ++ Q    E  
Sbjct: 804  RKKMDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREEN 863

Query: 619  TVLQELINVLKTD--------LLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIED 670
               ++L  V+K D        L +  E  L P    +   N + +     S+    K+++
Sbjct: 864  EKRKQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDE 923

Query: 671  QKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWT 730
            QKK LD  +  + N   EL+E     L    K+     E + + K+   QE   L N   
Sbjct: 924  QKKWLDEEVEKVLNQRQELEE-----LEADLKK----REAIVSKKEALLQEKSHLENKKL 974

Query: 731  ERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEG 790
                AL      I   L+ +++ + +K+  +         K     +   +E ++  Q+ 
Sbjct: 975  RSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKE-KDQLQKR 1033

Query: 791  TKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNL 847
               V+E +K+   L+   E +  + E+  E+L     Y +E   +         HNL
Sbjct: 1034 RHNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNL 1090



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 41/211 (19%), Positives = 92/211 (43%), Gaps = 2/211 (0%)

Query: 358  NILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKL-TVQE 416
            +I N+   N+       +K    +++R  R+    R++    I  +  ++   +L T QE
Sbjct: 831  SIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQE 890

Query: 417  EQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLV 476
            E +    E + A   +  + +   +D+  +LD+ K  L  + +++   ++ L+E +  L 
Sbjct: 891  EGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLK 950

Query: 477  KEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLD-RKKAVDQHNAEAQDIFG 535
            K E I S  E+  ++     +K L + +    D   + ++L+  ++ + + N + Q    
Sbjct: 951  KREAIVSKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTA 1010

Query: 536  KNLNSLFNNMEELIKDGSSKQKAMLEVHKTL 566
            +    +   +E L K+    QK    V + L
Sbjct: 1011 EEKTKISEQVEVLQKEKDQLQKRRHNVDEKL 1041


>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
          Length = 1153

 Score =  236 bits (601), Expect = 1e-61
 Identities = 151/397 (38%), Positives = 224/397 (56%), Gaps = 41/397 (10%)

Query: 16  GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGAS 75
           G +++V VR RPFN  E    +  I++       +         K + K+++FD  + + 
Sbjct: 3   GASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSI---INPKNPKEAPKSFSFDYSYWSH 59

Query: 76  TKQID--------VYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTW 127
           T   D        VY  +   +L     GYN  IFAYGQTG GK++TM G+         
Sbjct: 60  TSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGK--------- 110

Query: 128 EEDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQM 184
           +E+  AGIIP+   ++FEK+ DN  E   +SV+VS +EIY E + DLLNP +  + R++ 
Sbjct: 111 QEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVR- 169

Query: 185 FDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTI- 243
                   G  ++ L ++ V +  ++  +++ G   RT AAT MN  SSRSH+VF++   
Sbjct: 170 ---EHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFT 226

Query: 244 ---HMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
              H  ET +  E   K+ K++LVDLAGSE    +GA   R +E  NIN+SL TLG+VI+
Sbjct: 227 QKKHDNETNLSTE---KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVIS 283

Query: 301 ALVE------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAH 354
           AL E      +T  +PYR+S LT +L+++LGG +RT+++A +SPA +N +ETLSTL YA 
Sbjct: 284 ALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYAD 343

Query: 355 RAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAA 391
           RAK I     +N+    K L++E  EE+ RLK  L A
Sbjct: 344 RAKQIKCNAVINEDPNAK-LVRELKEEVTRLKDLLRA 379


>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
          Length = 1770

 Score =  236 bits (601), Expect = 1e-61
 Identities = 151/397 (38%), Positives = 224/397 (56%), Gaps = 41/397 (10%)

Query: 16  GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGAS 75
           G +++V VR RPFN  E    +  I++       +         K + K+++FD  + + 
Sbjct: 3   GASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSI---INPKNPKEAPKSFSFDYSYWSH 59

Query: 76  TKQID--------VYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTW 127
           T   D        VY  +   +L     GYN  IFAYGQTG GK++TM G+         
Sbjct: 60  TSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGK--------- 110

Query: 128 EEDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQM 184
           +E+  AGIIP+   ++FEK+ DN  E   +SV+VS +EIY E + DLLNP +  + R++ 
Sbjct: 111 QEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVR- 169

Query: 185 FDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTI- 243
                   G  ++ L ++ V +  ++  +++ G   RT AAT MN  SSRSH+VF++   
Sbjct: 170 ---EHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFT 226

Query: 244 ---HMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
              H  ET +  E   K+ K++LVDLAGSE    +GA   R +E  NIN+SL TLG+VI+
Sbjct: 227 QKKHDNETNLSTE---KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVIS 283

Query: 301 ALVE------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAH 354
           AL E      +T  +PYR+S LT +L+++LGG +RT+++A +SPA +N +ETLSTL YA 
Sbjct: 284 ALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYAD 343

Query: 355 RAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAA 391
           RAK I     +N+    K L++E  EE+ RLK  L A
Sbjct: 344 RAKQIKCNAVINEDPNAK-LVRELKEEVTRLKDLLRA 379


>gi|38569484 kinesin family member 21A [Homo sapiens]
          Length = 1661

 Score =  236 bits (601), Expect = 1e-61
 Identities = 234/871 (26%), Positives = 385/871 (44%), Gaps = 120/871 (13%)

Query: 18  NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTK 77
           +++V VR RP    E+    H      P   +V +           K +TFD VF   ++
Sbjct: 9   SVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFL--------GKDKAFTFDYVFDIDSQ 60

Query: 78  QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP 137
           Q  +Y   +  +++    GYN T+FAYGQTG GKT+TM      N     EE+   GII 
Sbjct: 61  QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVN---IVEEE--LGIIS 115

Query: 138 RTLHQIFEKLTD-------NGT---EFSVKVSLLEIYNEELFDLLNPSSDVSER-----L 182
           R +  +F+ + +       NG    +F V    LE+YNEE+ DL + + D+  +     +
Sbjct: 116 RAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNI 175

Query: 183 QMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVT 242
           ++ +D     G+   G+   TV+ + E+ Q L+ GA  RTTA+T MN  SSRSH++F  T
Sbjct: 176 RIHEDSTG--GIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIF--T 231

Query: 243 IHMKETTI----------DGEELVKIGKLN----------LVDLAGSENIGRSGAVDKRA 282
           IH+ +T +          D + + +  ++N           VDLAGSE + R+GA  +RA
Sbjct: 232 IHVCQTRVCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERA 291

Query: 283 REAGNINQSLLTLGRVITALVE---RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPA 339
           +E  +IN  LL LG VI+AL +   R  HVPYR+SKLTR+LQDSLGG ++T +IA +SP+
Sbjct: 292 KEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPS 351

Query: 340 SLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVY 399
             +  ETL+TL+YA+RA+NI NK  VNQ    +  I     EI RL+ +L   +    + 
Sbjct: 352 DRDFMETLNTLKYANRARNIKNKVMVNQDRASQQ-INALRSEITRLQMELMEYKTGKRII 410

Query: 400 ISE--ENFRVMSGKLTVQEEQIVELIEKIGAVEEEL----NRVTELFMDNKNEL------ 447
             E  E+   M  +  + + +   L  +I A++E +    +R+T+L  D  N +      
Sbjct: 411 DEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGE 470

Query: 448 --DQCKS----------DLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDA 495
             ++  +          DL+ K  E E   ++L++   +        S   +    +  +
Sbjct: 471 GNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSS 530

Query: 496 ASKLLNTVEETTKDVSGLHSKLDRKKA----------VDQHNAEAQDIFGKNLNSLFNNM 545
             + +  ++   KD+  L  K  RKK            DQ   E + +  +  N L    
Sbjct: 531 DKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEE 590

Query: 546 EELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFN 605
            + + D   +++   E    + G   S               S +    N    ++ I  
Sbjct: 591 SQEVSDHEDEEEEEEEEEDDIDGGESSDESD-----------SESDEKANYQADLANITC 639

Query: 606 MILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVA 665
            I  +Q L  E +   Q+ +  LK      L M+      + L+ +  L+++        
Sbjct: 640 EIAIKQKLIDELEN-SQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSE 698

Query: 666 DKIEDQKKELDGFLSILCNNLHELQ--ENTICSLVESQ----KQCGNLTEDLKTIKQTHS 719
           +K +  + E +  L  +   L  LQ  +     L+++Q    KQ   L +D+  +K+T  
Sbjct: 699 EKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTK- 757

Query: 720 QELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGF 779
               +LM         ++E+ E  +   S     I Q  KD   K     +   A     
Sbjct: 758 ---VRLMK-------QMKEEQEKARLTESRRNREIAQLKKD-QRKRDHQLRLLEAQKRNQ 806

Query: 780 SQELRNFNQEGTKLVEESVKHSDKLNGNLEK 810
              LR   +E T L  +    SDK+ G + +
Sbjct: 807 EVVLRRKTEEVTALRRQVRPMSDKVAGKVTR 837


>gi|83716024 kinesin family member 21B [Homo sapiens]
          Length = 1624

 Score =  235 bits (600), Expect = 1e-61
 Identities = 171/506 (33%), Positives = 260/506 (51%), Gaps = 70/506 (13%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQ 78
           ++V VR RP    E+    H      P   +V +           K +T+D VF   T Q
Sbjct: 9   VKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLL--------GKDKAFTYDFVFDLDTWQ 60

Query: 79  IDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPR 138
             +Y + V  +++    GYN T+ AYGQTG GKT+TM    +  +  T EE+   GIIPR
Sbjct: 61  EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMG---TGFDMATSEEEQ--GIIPR 115

Query: 139 TLHQIFEKLTDN----------GTEFSVKVSLLEIYNEELFDLLNPSSDVSER-----LQ 183
            +  +F  + +           G EF V    LE+YNEE+ DL + + D   R     ++
Sbjct: 116 AIAHLFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIK 175

Query: 184 MFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTI 243
           + +D     G+   G+    +H+++E+ Q L++GA  RTTA+T MN  SSRSH++F  TI
Sbjct: 176 IHEDANG--GIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIF--TI 231

Query: 244 HMKE--------------------TTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAR 283
           H+ +                    T    E      K + VDLAGSE + R+GA  +RA+
Sbjct: 232 HLCQMRMCTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAK 291

Query: 284 EAGNINQSLLTLGRVITALVERTP---HVPYRESKLTRILQDSLGGRTRTSIIATISPAS 340
           E  +IN  LL LG VI+AL +++    HVPYR+SKLTR+LQDSLGG ++T +IA +SP+ 
Sbjct: 292 EGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSD 351

Query: 341 LNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYI 400
            +  ETL+TL+YA+RA+NI NK  VNQ  T +  I     EI RL+ +L   +    V  
Sbjct: 352 RDFMETLNTLKYANRARNIKNKVVVNQDKTSQQ-ISALRAEIARLQMELMEYKAGKRVIG 410

Query: 401 SE--ENFRVMSGKLTVQEEQIVELIEKIGAVEEEL----NRVTELFMDNKNELDQCKSD- 453
            +  E +  +  +  + +++   L  ++ A++E +    NRVT+L     N L     D 
Sbjct: 411 EDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAGDG 470

Query: 454 -------LQNKTQELETTQKHLQETK 472
                  +QN  +E+E  +  L E++
Sbjct: 471 NEAIGALIQNYIREIEELRTKLLESE 496


>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
          Length = 1749

 Score =  234 bits (597), Expect = 3e-61
 Identities = 163/459 (35%), Positives = 250/459 (54%), Gaps = 50/459 (10%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL--ADKSSRKTYTFDMVFGA-- 74
           ++V VR RP N  E + +   +VE +  +  +          ++   K + FD  F +  
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65

Query: 75  ---STK---QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWE 128
              +TK   Q  V++ +   IL++   GYN  IFAYGQTG+GK+F+M G           
Sbjct: 66  ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQ------- 118

Query: 129 EDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQMF 185
                G+IPR    +F++++    E   F V+VS +EIYNE++ DLL+P      R  + 
Sbjct: 119 ----LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGS---RQSLK 171

Query: 186 DDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHM 245
                  G  + GL ++ V + +++  ++ +G   RT AAT MN  SSRSH+VF++ I  
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIII-- 229

Query: 246 KETTID---GEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITAL 302
            +T  D   G    K+ K++LVDLAGSE + ++GA  +R +E  NIN+SL TLG VI++L
Sbjct: 230 TQTLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSL 289

Query: 303 VE------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRA 356
            +      ++  VPYR+S LT +L+D+LGG ++TS+IATISPA+ N EETLSTL YA RA
Sbjct: 290 ADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRA 349

Query: 357 KNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQE 416
           K I+N   VN+    K +I+E  EE+E+L+  L+ A       + E        KL   E
Sbjct: 350 KRIVNHAVVNEDPNAK-VIRELREEVEKLREQLSQAEAMKAPELKE--------KLEESE 400

Query: 417 EQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQ 455
           + I EL       EE+L +  E+  + + +L+     L+
Sbjct: 401 KLIKELTV---TWEEKLRKTEEIAQERQRQLESMGISLE 436


>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
          Length = 1757

 Score =  234 bits (597), Expect = 3e-61
 Identities = 163/459 (35%), Positives = 250/459 (54%), Gaps = 50/459 (10%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL--ADKSSRKTYTFDMVFGA-- 74
           ++V VR RP N  E + +   +VE +  +  +          ++   K + FD  F +  
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65

Query: 75  ---STK---QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWE 128
              +TK   Q  V++ +   IL++   GYN  IFAYGQTG+GK+F+M G           
Sbjct: 66  ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQ------- 118

Query: 129 EDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQMF 185
                G+IPR    +F++++    E   F V+VS +EIYNE++ DLL+P      R  + 
Sbjct: 119 ----LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGS---RQSLK 171

Query: 186 DDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHM 245
                  G  + GL ++ V + +++  ++ +G   RT AAT MN  SSRSH+VF++ I  
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIII-- 229

Query: 246 KETTID---GEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITAL 302
            +T  D   G    K+ K++LVDLAGSE + ++GA  +R +E  NIN+SL TLG VI++L
Sbjct: 230 TQTLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSL 289

Query: 303 VE------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRA 356
            +      ++  VPYR+S LT +L+D+LGG ++TS+IATISPA+ N EETLSTL YA RA
Sbjct: 290 ADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRA 349

Query: 357 KNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQE 416
           K I+N   VN+    K +I+E  EE+E+L+  L+ A       + E        KL   E
Sbjct: 350 KRIVNHAVVNEDPNAK-VIRELREEVEKLREQLSQAEAMKAPELKE--------KLEESE 400

Query: 417 EQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQ 455
           + I EL       EE+L +  E+  + + +L+     L+
Sbjct: 401 KLIKELTV---TWEEKLRKTEEIAQERQRQLESMGISLE 436


>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
          Length = 1770

 Score =  234 bits (597), Expect = 3e-61
 Identities = 163/459 (35%), Positives = 250/459 (54%), Gaps = 50/459 (10%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL--ADKSSRKTYTFDMVFGA-- 74
           ++V VR RP N  E + +   +VE +  +  +          ++   K + FD  F +  
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65

Query: 75  ---STK---QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWE 128
              +TK   Q  V++ +   IL++   GYN  IFAYGQTG+GK+F+M G           
Sbjct: 66  ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQ------- 118

Query: 129 EDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQMF 185
                G+IPR    +F++++    E   F V+VS +EIYNE++ DLL+P      R  + 
Sbjct: 119 ----LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGS---RQSLK 171

Query: 186 DDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHM 245
                  G  + GL ++ V + +++  ++ +G   RT AAT MN  SSRSH+VF++ I  
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIII-- 229

Query: 246 KETTID---GEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITAL 302
            +T  D   G    K+ K++LVDLAGSE + ++GA  +R +E  NIN+SL TLG VI++L
Sbjct: 230 TQTLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSL 289

Query: 303 VE------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRA 356
            +      ++  VPYR+S LT +L+D+LGG ++TS+IATISPA+ N EETLSTL YA RA
Sbjct: 290 ADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRA 349

Query: 357 KNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQE 416
           K I+N   VN+    K +I+E  EE+E+L+  L+ A       + E        KL   E
Sbjct: 350 KRIVNHAVVNEDPNAK-VIRELREEVEKLREQLSQAEAMKAPELKE--------KLEESE 400

Query: 417 EQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQ 455
           + I EL       EE+L +  E+  + + +L+     L+
Sbjct: 401 KLIKELTV---TWEEKLRKTEEIAQERQRQLESMGISLE 436


>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
          Length = 1805

 Score =  234 bits (597), Expect = 3e-61
 Identities = 163/459 (35%), Positives = 250/459 (54%), Gaps = 50/459 (10%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGL--ADKSSRKTYTFDMVFGA-- 74
           ++V VR RP N  E + +   +VE +  +  +          ++   K + FD  F +  
Sbjct: 6   VKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCFWSMD 65

Query: 75  ---STK---QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWE 128
              +TK   Q  V++ +   IL++   GYN  IFAYGQTG+GK+F+M G           
Sbjct: 66  ESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHAEQ------- 118

Query: 129 EDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQMF 185
                G+IPR    +F++++    E   F V+VS +EIYNE++ DLL+P      R  + 
Sbjct: 119 ----LGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGS---RQSLK 171

Query: 186 DDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHM 245
                  G  + GL ++ V + +++  ++ +G   RT AAT MN  SSRSH+VF++ I  
Sbjct: 172 VREHKVLGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIII-- 229

Query: 246 KETTID---GEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITAL 302
            +T  D   G    K+ K++LVDLAGSE + ++GA  +R +E  NIN+SL TLG VI++L
Sbjct: 230 TQTLYDLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSL 289

Query: 303 VE------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRA 356
            +      ++  VPYR+S LT +L+D+LGG ++TS+IATISPA+ N EETLSTL YA RA
Sbjct: 290 ADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRA 349

Query: 357 KNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQE 416
           K I+N   VN+    K +I+E  EE+E+L+  L+ A       + E        KL   E
Sbjct: 350 KRIVNHAVVNEDPNAK-VIRELREEVEKLREQLSQAEAMKAPELKE--------KLEESE 400

Query: 417 EQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQ 455
           + I EL       EE+L +  E+  + + +L+     L+
Sbjct: 401 KLIKELTV---TWEEKLRKTEEIAQERQRQLESMGISLE 436


>gi|46852172 kinesin family member 13B [Homo sapiens]
          Length = 1826

 Score =  233 bits (594), Expect = 7e-61
 Identities = 158/460 (34%), Positives = 247/460 (53%), Gaps = 49/460 (10%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSR---KTYTFDMVFGAS 75
           ++V VR RP N  E       +V+ D  +  ++     L+   +R   K + +D  F + 
Sbjct: 6   VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSM 65

Query: 76  TKQID--------VYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTW 127
            + +         V++ +   IL     GYN  IFAYGQTG+GK++TM G          
Sbjct: 66  DESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQ------ 119

Query: 128 EEDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQM 184
                 G+IPR    +FE+      E   F V+VS +EIYNE++ DLL+P      R  +
Sbjct: 120 -----PGLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGS---RQTL 171

Query: 185 FDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTI- 243
                +  G  + GL ++ V +  ++  ++ +G   RT AAT MN  SSRSH+VF +T+ 
Sbjct: 172 KVREHSVLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLT 231

Query: 244 HMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALV 303
           H       G    K+GKL+LVDLAGSE   ++GA   R +E  NIN+SL TLG VI+AL 
Sbjct: 232 HTLYDVKSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALA 291

Query: 304 ERTP------HVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAK 357
           +++        VPYR+S LT +L+DSLGG ++T+++AT+SPA+ N +ETLSTL YA RAK
Sbjct: 292 DQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAK 351

Query: 358 NILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEE 417
           +I+N   VN+    + +I++  EE+E+L+  L  A              + S +L  + E
Sbjct: 352 HIVNHAVVNEDPNAR-IIRDLREEVEKLREQLTKAE------------AMKSPELKDRLE 398

Query: 418 QIVELIEKIGAV-EEELNRVTELFMDNKNELDQCKSDLQN 456
           +  +LI+++    EE+L +  E+  + + +L+     LQ+
Sbjct: 399 ESEKLIQEMTVTWEEKLRKTEEIAQERQKQLESLGISLQS 438


>gi|156616271 kinesin family member 19 [Homo sapiens]
          Length = 998

 Score =  231 bits (590), Expect = 2e-60
 Identities = 174/509 (34%), Positives = 265/509 (52%), Gaps = 51/509 (10%)

Query: 13  EEKGKNIQVVVRCRPFNLAE---------RKASAHSIVECDPVRKEVSVRTGGLADKSSR 63
           + K + + V +R RP ++AE          K     +V  DP+     +     A +S  
Sbjct: 6   DSKDQQLMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILR---AHRSRE 62

Query: 64  KTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNE 123
           K+Y FD+ F  +  Q  VY++    +++ VI GYN T+FAYG TG GKT+TM G      
Sbjct: 63  KSYLFDVAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGT----- 117

Query: 124 EYTWEEDPLAGIIPRTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSER 181
               +++P  GI  +TL+ +F  +  T N  E+ V +S LEIYNE + DLLNPS    E 
Sbjct: 118 ----DQEP--GIYVQTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGYLEL 171

Query: 182 LQMFDDPRNKRGVI-IKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFS 240
            +      + +GVI + G+ E++  N  E+ Q+L KG  +RT   T  N  SSRSH+V  
Sbjct: 172 RE------DSKGVIQVAGITEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQ 225

Query: 241 VTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
           VT+  +    +  + V+ G+L ++DLAGSE   ++    +R +E  +IN+SLL LG  I 
Sbjct: 226 VTVRQRSRVKNILQEVRQGRLFMIDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCIN 285

Query: 301 ALVER--TPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKN 358
           AL ++    ++ YR+SKLTR+L+DSLGG +RT +IA ISPAS   EE+ +TL YA RAKN
Sbjct: 286 ALSDKGSNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKN 345

Query: 359 ILNKPEVNQKLTKKAL-IKEYTE-------EIERLKRDLAAAREKNGVYISEENFRVMSG 410
           I  K  V Q L   +  I +YT        EI+RLKR +     +      ++   +   
Sbjct: 346 I--KTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHI 403

Query: 411 KLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELE-TTQKHLQ 469
           +  VQ          +G + E+L    +  MD +  L     +L+N+  E++  T +HL 
Sbjct: 404 QAEVQLHSGQGEKAGMGQLREQLASAFQEQMDVRRRL----LELENRAMEVQIDTSRHL- 458

Query: 470 ETKLQLVKEEYITSALESTEEKLHDAASK 498
              +   K E    AL+  EE+  +  +K
Sbjct: 459 -LTIAGWKHEKSRRALKWREEQRKECYAK 486


>gi|148612831 kinesin family member 18A [Homo sapiens]
          Length = 898

 Score =  231 bits (589), Expect = 3e-60
 Identities = 182/577 (31%), Positives = 286/577 (49%), Gaps = 63/577 (10%)

Query: 12  KEEKGKNIQVVVRCRPFNLAERKASAHSIVEC--------DPVRKEVSVRTGG------- 56
           +E+   +++VVVR RP N  E+ A  H +V          DP ++EVS   G        
Sbjct: 5   EEDLCHHMKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNV 64

Query: 57  LADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTME 116
           +  ++    + FD VF  ++ Q +V+     PIL   + GYNCT+ AYG TG GKT TM 
Sbjct: 65  IKKQNKDLKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTML 124

Query: 117 GERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTE--FSVKVSLLEIYNEELFDLLNP 174
           G           ++P  G++  T+  +++ + +   E   S  VS LE+YNE++ DLL  
Sbjct: 125 GSA---------DEP--GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVN 173

Query: 175 SSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSR 234
           S  ++ R         ++GV++ GL      + +E+  +L+ G   RT   T MNA SSR
Sbjct: 174 SGPLAVRED------TQKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSR 227

Query: 235 SHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLT 294
           SH+VF + +  ++ T    + V+I K++L+DLAGSE    SGA   R  E  NIN+SLL 
Sbjct: 228 SHAVFQIYLRQQDKTASINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLA 287

Query: 295 LGRVITALVE---RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLE 351
           LG VI AL +   +  H+PYR SKLTR+L+DSLGG  +T +IA +SP+S+  ++T +TL+
Sbjct: 288 LGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLK 347

Query: 352 YAHRAKNI-----LNKPEVNQKLTKKALI-KEYTEEIERLKRDLAAAREKNGVYISEENF 405
           YA+RAK+I      N   VN  +T+   I  E   EI  LK  L A  E+       +  
Sbjct: 348 YANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEILLLKEKLKAYEEQKAFTNENDQA 407

Query: 406 RVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMD-----NKNEL-----DQCKSDLQ 455
           ++M      QE++I    E +  + +    + + ++       +NEL      QC   ++
Sbjct: 408 KLMIS--NPQEKEIERFQEILNCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIE 465

Query: 456 NKTQE---LETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVS- 511
               E    + T K      +   +  Y+    E  E K  D  +  L+ VE+    +S 
Sbjct: 466 MMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREE-ELKQFDENTNWLHRVEKEMGLLSQ 524

Query: 512 GLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEEL 548
             H   + KK +  H+   Q+   K+L +   +M +L
Sbjct: 525 NGHIPKELKKDLHCHHLHLQN---KDLKAQIRHMMDL 558


>gi|40254834 kinesin family member 1C [Homo sapiens]
          Length = 1103

 Score =  231 bits (588), Expect = 4e-60
 Identities = 149/397 (37%), Positives = 224/397 (56%), Gaps = 41/397 (10%)

Query: 16  GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGAS 75
           G +++V VR RPFN  E    A  +V    ++   +        K + K++TFD  + + 
Sbjct: 3   GASVKVAVRVRPFNARETSQDAKCVVS---MQGNTTSIINPKQSKDAPKSFTFDYSYWSH 59

Query: 76  TKQID--------VYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTW 127
           T   D        VYR +   +L     GYN  IFAYGQTG GK++TM G + P ++   
Sbjct: 60  TSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQEPGQQ--- 116

Query: 128 EEDPLAGIIPRTLHQIFEKLTDNGT---EFSVKVSLLEIYNEELFDLLNPSSDVSERLQM 184
                 GI+P+    +F ++++N +    +SV+VS +EIY E + DLLNP S  S R++ 
Sbjct: 117 ------GIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVR- 169

Query: 185 FDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTI- 243
                   G  ++ L ++ V +  ++  +++ G   RT AAT MN  SSRSH+VF++   
Sbjct: 170 ---EHPILGPYVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFT 226

Query: 244 ---HMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
              H + T +D E   K+ K++LVDLAGSE    SGA   R +E  NIN+SL TLG+VI+
Sbjct: 227 QRCHDQLTGLDSE---KVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVIS 283

Query: 301 ALVE------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAH 354
           AL +      ++  +PYR+S LT +L+++LGG +RT++IA +SPA +N EETLSTL YA 
Sbjct: 284 ALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYAD 343

Query: 355 RAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAA 391
           R K I     +N+    + LI+E  EE+ RL+  L A
Sbjct: 344 RTKQIRCNAIINEDPNAR-LIRELQEEVARLRELLMA 379


>gi|122937289 kinesin family member 18B [Homo sapiens]
          Length = 855

 Score =  230 bits (587), Expect = 5e-60
 Identities = 151/401 (37%), Positives = 222/401 (55%), Gaps = 38/401 (9%)

Query: 19  IQVVVRCRPFNLAERKASAHSIVECDPVRKEV-----------SVRTGGLADKSSRK--- 64
           +QVVVR RP    E  +    +V+    R  V            ++ GG  D   +K   
Sbjct: 8   LQVVVRVRPPTPRELDSQRRPVVQVVDERVLVFNPEEPDGGFPGLKWGGTHDGPKKKGKD 67

Query: 65  -TYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNE 123
            T+ FD VFG +  Q DV++     +LD  + GYNC++FAYG TG GKT TM G      
Sbjct: 68  LTFVFDRVFGEAATQQDVFQHTTHSVLDSFLQGYNCSVFAYGATGAGKTHTMLGR----- 122

Query: 124 EYTWEEDPLAGIIPRTLHQIFEKLTDNGTE--FSVKVSLLEIYNEELFDLLNPSSDVSER 181
               E DP  GI+  T  +++ +L     E  F V +S  E+YNE++ DLL P   ++ R
Sbjct: 123 ----EGDP--GIMYLTTVELYRRLEARQQEKHFEVLISYQEVYNEQIHDLLEPKGPLAIR 176

Query: 182 LQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSV 241
               +DP   +GV+++GL      + +++ +IL +G   RT   T  NA SSRSH++F +
Sbjct: 177 ----EDP--DKGVVVQGLSFHQPASAEQLLEILTRGNRNRTQHPTDANATSSRSHAIFQI 230

Query: 242 TIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITA 301
            +  ++      + V++ K++L+DLAGSE    + A  +R RE  NIN+SLL L  V+ A
Sbjct: 231 FVKQQDRVPGLTQAVQVAKMSLIDLAGSERASSTHAKGERLREGANINRSLLALINVLNA 290

Query: 302 LVE---RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKN 358
           L +   R  HVPYR+SKLTR+L+DSLGG  RT +IA ISP+SL  E+T +TL+YA RAK 
Sbjct: 291 LADAKGRKTHVPYRDSKLTRLLKDSLGGNCRTVMIAAISPSSLTYEDTYNTLKYADRAKE 350

Query: 359 ILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVY 399
           I    + N   +    I +Y    ++L+ ++AA R+K  VY
Sbjct: 351 IRLSLKSN-VTSLDCHISQYATICQQLQAEVAALRKKLQVY 390


>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
          Length = 1690

 Score =  229 bits (584), Expect = 1e-59
 Identities = 148/405 (36%), Positives = 226/405 (55%), Gaps = 48/405 (11%)

Query: 16  GKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGAS 75
           G +++V VR RPFN  E    +  I++   +    +        K + K+++FD  + + 
Sbjct: 3   GASVKVAVRVRPFNSREMSRDSKCIIQ---MSGSTTTIVNPKQPKETPKSFSFDYSYWSH 59

Query: 76  TKQID--------VYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTW 127
           T   D        VYR +   +L     GYN  IFAYGQTG GK++TM G++  +++   
Sbjct: 60  TSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQ--- 116

Query: 128 EEDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLNPSSDVSERLQM 184
                 GIIP+    +F ++ D   +   +SV+VS +EIY E + DLLNP +  + R++ 
Sbjct: 117 ------GIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVR- 169

Query: 185 FDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTI- 243
                   G  ++ L ++ V + +++  +++ G   RT AAT MN  SSRSH+VF++   
Sbjct: 170 ---EHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFT 226

Query: 244 ---HMKETTIDGEELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVIT 300
              H  ET I  E   K+ K++LVDLAGSE    +GA   R +E  NIN+SL TLG+VI+
Sbjct: 227 QKRHDAETNITTE---KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVIS 283

Query: 301 ALVE------------RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEETLS 348
           AL E            +T  +PYR+S LT +L+++LGG +RT+++A +SPA +N +ETLS
Sbjct: 284 ALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLS 343

Query: 349 TLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAR 393
           TL YA RAK I     +N+    K LI+E  +E+ RL RDL  A+
Sbjct: 344 TLRYADRAKQIRCNAVINEDPNNK-LIRELKDEVTRL-RDLLYAQ 386


>gi|7661878 kinesin family member 14 [Homo sapiens]
          Length = 1648

 Score =  225 bits (573), Expect = 2e-58
 Identities = 166/477 (34%), Positives = 260/477 (54%), Gaps = 52/477 (10%)

Query: 6   NSSAKKKEEKGKNIQVVV--RCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSR 63
           N+SA K   K +N QV V  R RPF   E+   A  +V      KE++V      D    
Sbjct: 344 NTSAGKDPLKVENSQVTVAVRVRPFTKREKIEKASQVVFMSG--KEITVEH---PDTKQV 398

Query: 64  KTYTFDMVFGASTK-------QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTME 116
             + +D+ F +  +       Q  VY  +  P+L+    G+N  +FAYGQTG+GK++TM 
Sbjct: 399 YNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMM 458

Query: 117 GERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTE---FSVKVSLLEIYNEELFDLLN 173
           G         + E+P  GIIPR    +F ++    T+   + +++S  E+YNE++ DLL 
Sbjct: 459 G---------FSEEP--GIIPRFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLV 507

Query: 174 PSSDVSERLQMFDDPRNK-RGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYS 232
              +  +R Q      +   G  ++ L    V +  ++   LE G  +R TAAT MN  S
Sbjct: 508 CKDENGQRKQPLRVREHPVYGPYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKS 567

Query: 233 SRSHSVFSVTIHMKETT-IDGEELVK--IGKLNLVDLAGSENIGRSGAVDKRAREAGNIN 289
           SRSHSVF++ +   +T  ++GEE       ++NL+DLAGSE    +     R +E  +IN
Sbjct: 568 SRSHSVFTLVMTQTKTEFVEGEEHDHRITSRINLIDLAGSERCSTAHTNGDRLKEGVSIN 627

Query: 290 QSLLTLGRVITALVE----RTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEE 345
           +SLLTLG+VI+AL E    R+  +PYRES LT +L++SLGG ++T++IATISPA+ N+EE
Sbjct: 628 KSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASNIEE 687

Query: 346 TLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENF 405
           TLSTL YA++A+ I+N  +VN+ +  K LI+E   EI +LK     A ++N   I  E +
Sbjct: 688 TLSTLRYANQARLIVNIAKVNEDMNAK-LIRELKAEIAKLK-----AAQRNSRNIDPERY 741

Query: 406 RVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELE 462
           R+         ++I  L  K+   E ++  +  ++   K + +Q +     +T+EL+
Sbjct: 742 RLC-------RQEITSLRMKLHQQERDMAEMQRVW---KEKFEQAEKRKLQETKELQ 788


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,782,991
Number of Sequences: 37866
Number of extensions: 1594609
Number of successful extensions: 8327
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 166
Number of HSP's successfully gapped in prelim test: 583
Number of HSP's that attempted gapping in prelim test: 5425
Number of HSP's gapped (non-prelim): 2140
length of query: 1056
length of database: 18,247,518
effective HSP length: 113
effective length of query: 943
effective length of database: 13,968,660
effective search space: 13172446380
effective search space used: 13172446380
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.