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Search of human proteins with 13654270
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13654270 LAS1-like [Homo sapiens]
(734 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13654270 LAS1-like [Homo sapiens] 1502 0.0
gi|17975763 myelin transcription factor 1 [Homo sapiens] 67 8e-11
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 59 2e-08
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 56 1e-07
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 56 1e-07
gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo ... 55 2e-07
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 55 2e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 54 5e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 54 5e-07
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 54 7e-07
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 54 7e-07
gi|4757900 calreticulin precursor [Homo sapiens] 54 7e-07
gi|4505999 protein phosphatase 1G [Homo sapiens] 54 7e-07
gi|29826282 protein phosphatase 1G [Homo sapiens] 54 7e-07
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens] 53 1e-06
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens] 53 1e-06
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 52 2e-06
gi|4503257 death-domain associated protein isoform a [Homo sapiens] 52 3e-06
gi|215422388 death-domain associated protein isoform a [Homo sap... 52 3e-06
gi|215422366 death-domain associated protein isoform b [Homo sap... 52 3e-06
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 52 3e-06
gi|4508005 tripartite motif-containing 26 [Homo sapiens] 52 3e-06
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 51 3e-06
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 51 4e-06
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 51 4e-06
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)... 50 6e-06
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)... 50 6e-06
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)... 50 6e-06
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 50 6e-06
gi|66472382 nischarin [Homo sapiens] 50 6e-06
>gi|13654270 LAS1-like [Homo sapiens]
Length = 734
Score = 1502 bits (3889), Expect = 0.0
Identities = 734/734 (100%), Positives = 734/734 (100%)
Query: 1 MSWESGAGPGLGSQGMDLVWSAWYGKCVKGKGSLPLSAHGIVVAWLSRAEWDQVTVYLFC 60
MSWESGAGPGLGSQGMDLVWSAWYGKCVKGKGSLPLSAHGIVVAWLSRAEWDQVTVYLFC
Sbjct: 1 MSWESGAGPGLGSQGMDLVWSAWYGKCVKGKGSLPLSAHGIVVAWLSRAEWDQVTVYLFC 60
Query: 61 DDHKLQRYALNRITVWRSRSGNELPLAVASTADLIRCKLLDVTGGLGTDELRLLYGMALV 120
DDHKLQRYALNRITVWRSRSGNELPLAVASTADLIRCKLLDVTGGLGTDELRLLYGMALV
Sbjct: 61 DDHKLQRYALNRITVWRSRSGNELPLAVASTADLIRCKLLDVTGGLGTDELRLLYGMALV 120
Query: 121 RFVNLISERKTKFAKVPLKCLAQEVNIPDWIVDLRHELTHKKMPHINDCRRGCYFVLDWL 180
RFVNLISERKTKFAKVPLKCLAQEVNIPDWIVDLRHELTHKKMPHINDCRRGCYFVLDWL
Sbjct: 121 RFVNLISERKTKFAKVPLKCLAQEVNIPDWIVDLRHELTHKKMPHINDCRRGCYFVLDWL 180
Query: 181 QKTYWCRQLENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDV 240
QKTYWCRQLENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDV
Sbjct: 181 QKTYWCRQLENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDV 240
Query: 241 KADGDSKGSEEVDSHCKKALSHKELYERARELLVSYEEEQFTVLEKFRYLPKAIKAWNNP 300
KADGDSKGSEEVDSHCKKALSHKELYERARELLVSYEEEQFTVLEKFRYLPKAIKAWNNP
Sbjct: 241 KADGDSKGSEEVDSHCKKALSHKELYERARELLVSYEEEQFTVLEKFRYLPKAIKAWNNP 300
Query: 301 SPRVECVLAELKGVTCENREAVLDAFLDDGFLVPTFEQLAALQIEYEDGQTEVQRGEGTD 360
SPRVECVLAELKGVTCENREAVLDAFLDDGFLVPTFEQLAALQIEYEDGQTEVQRGEGTD
Sbjct: 301 SPRVECVLAELKGVTCENREAVLDAFLDDGFLVPTFEQLAALQIEYEDGQTEVQRGEGTD 360
Query: 361 PKSHKNVDLNDVLVPKPFSQFWQPLLRGLHSQNFTQALLERMLSELPALGISGIRPTYIL 420
PKSHKNVDLNDVLVPKPFSQFWQPLLRGLHSQNFTQALLERMLSELPALGISGIRPTYIL
Sbjct: 361 PKSHKNVDLNDVLVPKPFSQFWQPLLRGLHSQNFTQALLERMLSELPALGISGIRPTYIL 420
Query: 421 RWTVELIVANTKTGRNARRFSAGQWEARRGWRLFNCSASLDWPRMVESCLGSPCWASPQL 480
RWTVELIVANTKTGRNARRFSAGQWEARRGWRLFNCSASLDWPRMVESCLGSPCWASPQL
Sbjct: 421 RWTVELIVANTKTGRNARRFSAGQWEARRGWRLFNCSASLDWPRMVESCLGSPCWASPQL 480
Query: 481 LRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVK 540
LRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVK
Sbjct: 481 LRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVK 540
Query: 541 PASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDD 600
PASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDD
Sbjct: 541 PASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDD 600
Query: 601 EEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTE 660
EEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTE
Sbjct: 601 EEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTE 660
Query: 661 DPAELMLENYDTMYLLDQPVLEQRLEPSTCKTDTLGLSCGVGSGNCSNSSSSNFEGLLWS 720
DPAELMLENYDTMYLLDQPVLEQRLEPSTCKTDTLGLSCGVGSGNCSNSSSSNFEGLLWS
Sbjct: 661 DPAELMLENYDTMYLLDQPVLEQRLEPSTCKTDTLGLSCGVGSGNCSNSSSSNFEGLLWS 720
Query: 721 QGQLHGLKTGLQLF 734
QGQLHGLKTGLQLF
Sbjct: 721 QGQLHGLKTGLQLF 734
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 66.6 bits (161), Expect = 8e-11
Identities = 50/167 (29%), Positives = 85/167 (50%), Gaps = 15/167 (8%)
Query: 465 MVESCLGSPCWASPQLLRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASP 524
+VE LG P ++ ++ +A +G EE EK L I +V+ +E S
Sbjct: 179 LVEEDLGQAAKPGPGIVHLLQEA-AEGAASEEGEKGLFI----QPEDAEEVVEVTTERSQ 233
Query: 525 IGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEE 584
D S++ A+S S+ K E+ + +EEE+EE++ ++ EEEEE
Sbjct: 234 --------DLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEED--EEEEEEEEE 283
Query: 585 NDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRG 631
+++EEEEE+E++E++EEE+ E P QE + +A+ + RG
Sbjct: 284 EEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRG 330
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 58.9 bits (141), Expect = 2e-08
Identities = 46/140 (32%), Positives = 71/140 (50%), Gaps = 11/140 (7%)
Query: 480 LLRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTL---DSLY 536
++ I++ M Q E Q++ LR T SGE S + +P G S T ++LY
Sbjct: 193 IMNQIYEDMRQQEKVERQQEALRAQKA-TVSGEASPARSSGNDAPPGGSKETWGLQETLY 251
Query: 537 WSVKPASSSFGSEAKAQQ-------QEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQE 589
V+ S +F + Q +EE+ ND +EE +E + EEEEE +D+E
Sbjct: 252 GFVQNPSLAFSPNPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEE 311
Query: 590 EEEEDEDDEDDEEEDRMEVG 609
EE EDE++E+ EE + +E G
Sbjct: 312 EEVEDEEEEEVEEAEYVEEG 331
Score = 43.1 bits (100), Expect = 0.001
Identities = 23/56 (41%), Positives = 35/56 (62%)
Query: 548 SEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEE 603
SE + + ++E+ V D +EEE EE E + + EE EE + +EEEE E++E EE
Sbjct: 301 SEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 56.2 bits (134), Expect = 1e-07
Identities = 29/78 (37%), Positives = 52/78 (66%), Gaps = 3/78 (3%)
Query: 557 EQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVG-PFSTGQ 615
E+G + ++ +E EE+E D+ EEEEE +++E+EEE+E++E++EEE+ ++ P T
Sbjct: 1057 ERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116
Query: 616 ESPTAENAR--LLAQKRG 631
+S + R +L +KRG
Sbjct: 1117 QSVAIKRKRPFVLKKKRG 1134
Score = 46.6 bits (109), Expect = 8e-05
Identities = 26/68 (38%), Positives = 40/68 (58%), Gaps = 3/68 (4%)
Query: 543 SSSFGSEAKAQQQEE---QGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDED 599
++S S AK Q + + V E + E+ + EEEEE +D+EEEEE+E++E+
Sbjct: 1030 ANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEE 1089
Query: 600 DEEEDRME 607
DEEE+ E
Sbjct: 1090 DEEEEEEE 1097
Score = 46.2 bits (108), Expect = 1e-04
Identities = 50/215 (23%), Positives = 87/215 (40%), Gaps = 15/215 (6%)
Query: 512 ENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVN-DVKEEEKE 570
E V+E E S SP + + VK + + + +++E V+ + EK
Sbjct: 1285 EQVTVEEQKETSEGKTSPSPI-RIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKP 1343
Query: 571 EKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKR 630
E +++ + EEEEE +EEEEE+E++E +EEE V G +S E + +K
Sbjct: 1344 EDDLIKPEEEEEEE---EEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKE 1400
Query: 631 GALQGSAWQVS---------SEDVRWDTFPLGRMPGQTEDPAELMLENYDTMYLLDQPVL 681
+ + + +ED D M + EL E++ + + L
Sbjct: 1401 DSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQETFL 1460
Query: 682 EQRLEPSTCKTDTLGLSCGVGSGNCSNSSSSNFEG 716
+ ++P + L + CGV NS G
Sbjct: 1461 DLNVQPGHSNPEVL-MDCGVDLTASCNSEPKELAG 1494
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 55.8 bits (133), Expect = 1e-07
Identities = 25/59 (42%), Positives = 42/59 (71%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRME 607
E + +++EE+ D +EEE++E+E ++ EEEEE +++ EEEE E +E++EEED E
Sbjct: 895 EEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEE 953
Score = 51.6 bits (122), Expect = 3e-06
Identities = 30/84 (35%), Positives = 49/84 (58%), Gaps = 7/84 (8%)
Query: 521 EASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVE 580
E +P G P L+ + SS E + +++EE+ EEE+EE+E ++ E
Sbjct: 863 EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEE-------EEEEEEEEDFEEEEE 915
Query: 581 EEEENDDQEEEEEDEDDEDDEEED 604
+EEE ++EEEEE+E +E+ EEE+
Sbjct: 916 DEEEYFEEEEEEEEEFEEEFEEEE 939
Score = 51.6 bits (122), Expect = 3e-06
Identities = 24/48 (50%), Positives = 35/48 (72%)
Query: 560 SVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRME 607
++N EEE+EE+E ++ EEEEE +D EEEEEDE++ +EEE+ E
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEE 929
Score = 42.7 bits (99), Expect = 0.001
Identities = 22/79 (27%), Positives = 40/79 (50%)
Query: 566 EEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENARL 625
EE+ + EEEEE +++EEEEE+E++E+D EE+ + + +E E
Sbjct: 875 EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934
Query: 626 LAQKRGALQGSAWQVSSED 644
++ G L+ + E+
Sbjct: 935 FEEEEGELEEEEEEEDEEE 953
>gi|239745093 PREDICTED: hypothetical protein XP_002343359 [Homo
sapiens]
Length = 142
Score = 55.5 bits (132), Expect = 2e-07
Identities = 37/134 (27%), Positives = 64/134 (47%), Gaps = 11/134 (8%)
Query: 496 EQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQ 555
E +++L Y S +L + S + + P TL S G+ A+ Q+
Sbjct: 17 ENDRILLSTFPYPHSKRENLAGLTNSTSSVKEEPPTL---------RHSMAGTSARKSQR 67
Query: 556 EEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFS--T 613
E+ + + EEK +E + E+E + +EEEEE+E++E++EEE+ E FS T
Sbjct: 68 REEKRREEKRREEKRREEKRREGKRREKEEEKEEEEEEEEEEEEEEEEEEEEEVSFSLAT 127
Query: 614 GQESPTAENARLLA 627
+ E RL++
Sbjct: 128 RERETETEEKRLIS 141
Score = 32.7 bits (73), Expect = 1.2
Identities = 19/62 (30%), Positives = 35/62 (56%), Gaps = 8/62 (12%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
E K +++EE+ KEEE+EE+E ++ EEEEE +++ + + E E++ +
Sbjct: 89 EGKRREKEEE------KEEEEEEEE--EEEEEEEEEEEEEVSFSLATRERETETEEKRLI 140
Query: 609 GP 610
P
Sbjct: 141 SP 142
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 55.1 bits (131), Expect = 2e-07
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 6/106 (5%)
Query: 564 VKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENA 623
V + K E E L +Q+ EEEE +++EEEEE+E++E++EEE+ E G Q + +
Sbjct: 283 VDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESG----NQSDRSGSSG 338
Query: 624 RLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMP-GQTEDPAELMLE 668
R A+K+ + S W S R P + P G + D + L E
Sbjct: 339 RRKAKKKWR-KDSPWVKPSRKRRKREPPRAKEPRGVSNDTSSLETE 383
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 53.9 bits (128), Expect = 5e-07
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query: 542 ASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQV--------EEEEENDDQEEEEE 593
+S S + + EE+G DV+E+E+ E++ D+ EEEEE +++EEEEE
Sbjct: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246
Query: 594 DEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSE 643
+E+ E DE + + E + T E+ + + + GS S E
Sbjct: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDE 296
Score = 45.8 bits (107), Expect = 1e-04
Identities = 24/68 (35%), Positives = 42/68 (61%), Gaps = 4/68 (5%)
Query: 543 SSSFGSE---AKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDED 599
S +GS+ + +EQG+ N EEE E++V D+ EE+ +D+E +E+ E++E+
Sbjct: 176 SEEYGSDHETGSSGSSDEQGN-NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234
Query: 600 DEEEDRME 607
+EEE+ E
Sbjct: 235 EEEEEEEE 242
Score = 36.6 bits (83), Expect = 0.086
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 542 ASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEE-DEDDEDD 600
AS S S + EE GS ++ +++ + EEE +D EE+EE +ED E+D
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
Query: 601 EEED 604
EE D
Sbjct: 223 EEVD 226
Score = 33.5 bits (75), Expect = 0.72
Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 7/71 (9%)
Query: 563 DVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDE-----EEDRMEVGPFSTGQES 617
D +EE+ E VL D + E E DD+ E E D++++ + DRME T ++
Sbjct: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRME--STDTKRQK 61
Query: 618 PTAENARLLAQ 628
P+ + +L+++
Sbjct: 62 PSVHSRQLVSK 72
Score = 32.3 bits (72), Expect = 1.6
Identities = 16/65 (24%), Positives = 33/65 (50%)
Query: 188 QLENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSK 247
++E E E++E E EEE++EE++ ++ ++ E + + D +++
Sbjct: 214 EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDS 273
Query: 248 GSEEV 252
GSE V
Sbjct: 274 GSESV 278
Score = 31.6 bits (70), Expect = 2.8
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 13/83 (15%)
Query: 190 ENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQD-DGKSTESD--------- 239
+ + E E EE E EEE++EE++ D +QK E D D +S SD
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFT 281
Query: 240 ---VKADGDSKGSEEVDSHCKKA 259
V++ + GS+E K+A
Sbjct: 282 DGSVRSGSGTDGSDEKKKERKRA 304
Score = 30.8 bits (68), Expect = 4.7
Identities = 16/76 (21%), Positives = 35/76 (46%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
+ + +++EE+ + +EEE+E ++ DQ EE + D + E + + + +
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRS 287
Query: 609 GPFSTGQESPTAENAR 624
G + G + E R
Sbjct: 288 GSGTDGSDEKKKERKR 303
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 53.9 bits (128), Expect = 5e-07
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 8/110 (7%)
Query: 542 ASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQV--------EEEEENDDQEEEEE 593
+S S + + EE+G DV+E+E+ E++ D+ EEEEE +++EEEEE
Sbjct: 187 SSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEE 246
Query: 594 DEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSE 643
+E+ E DE + + E + T E+ + + + GS S E
Sbjct: 247 EEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRSGSGTDGSDE 296
Score = 45.8 bits (107), Expect = 1e-04
Identities = 24/68 (35%), Positives = 42/68 (61%), Gaps = 4/68 (5%)
Query: 543 SSSFGSE---AKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDED 599
S +GS+ + +EQG+ N EEE E++V D+ EE+ +D+E +E+ E++E+
Sbjct: 176 SEEYGSDHETGSSGSSDEQGN-NTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEE 234
Query: 600 DEEEDRME 607
+EEE+ E
Sbjct: 235 EEEEEEEE 242
Score = 36.6 bits (83), Expect = 0.086
Identities = 23/64 (35%), Positives = 34/64 (53%), Gaps = 1/64 (1%)
Query: 542 ASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEE-DEDDEDD 600
AS S S + EE GS ++ +++ + EEE +D EE+EE +ED E+D
Sbjct: 163 ASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEED 222
Query: 601 EEED 604
EE D
Sbjct: 223 EEVD 226
Score = 33.5 bits (75), Expect = 0.72
Identities = 21/71 (29%), Positives = 38/71 (53%), Gaps = 7/71 (9%)
Query: 563 DVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDE-----EEDRMEVGPFSTGQES 617
D +EE+ E VL D + E E DD+ E E D++++ + DRME T ++
Sbjct: 4 DSREEKDGELNVLDDILTEVPEQDDELYNPESEQDKNEKKGSKRKSDRME--STDTKRQK 61
Query: 618 PTAENARLLAQ 628
P+ + +L+++
Sbjct: 62 PSVHSRQLVSK 72
Score = 32.3 bits (72), Expect = 1.6
Identities = 16/65 (24%), Positives = 33/65 (50%)
Query: 188 QLENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSK 247
++E E E++E E EEE++EE++ ++ ++ E + + D +++
Sbjct: 214 EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDS 273
Query: 248 GSEEV 252
GSE V
Sbjct: 274 GSESV 278
Score = 31.6 bits (70), Expect = 2.8
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 13/83 (15%)
Query: 190 ENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQD-DGKSTESD--------- 239
+ + E E EE E EEE++EE++ D +QK E D D +S SD
Sbjct: 222 DEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFT 281
Query: 240 ---VKADGDSKGSEEVDSHCKKA 259
V++ + GS+E K+A
Sbjct: 282 DGSVRSGSGTDGSDEKKKERKRA 304
Score = 30.8 bits (68), Expect = 4.7
Identities = 16/76 (21%), Positives = 35/76 (46%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
+ + +++EE+ + +EEE+E ++ DQ EE + D + E + + + +
Sbjct: 228 DGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSFTDGSVRS 287
Query: 609 GPFSTGQESPTAENAR 624
G + G + E R
Sbjct: 288 GSGTDGSDEKKKERKR 303
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 53.5 bits (127), Expect = 7e-07
Identities = 28/68 (41%), Positives = 45/68 (66%), Gaps = 4/68 (5%)
Query: 538 SVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDD 597
SV ++ E AQQ G + +E E+EE+EV ++ EEE+E D++EEE+E+E +
Sbjct: 98 SVARTAALVAEECSAQQ----GLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKE 153
Query: 598 EDDEEEDR 605
ED+EEE++
Sbjct: 154 EDEEEEEK 161
Score = 49.7 bits (117), Expect = 1e-05
Identities = 22/56 (39%), Positives = 40/56 (71%)
Query: 552 AQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRME 607
A++ Q + +EE +EE+E + ++ +EEE+ +D+EEEE++E+ E+DEEE+ E
Sbjct: 107 AEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKE 162
Score = 45.1 bits (105), Expect = 2e-04
Identities = 24/60 (40%), Positives = 38/60 (63%), Gaps = 3/60 (5%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
E + ++EE+ + KEEEKEE E ++ E+EEE ++ EEEEE E + +EE+ E+
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDE---EEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEI 175
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/67 (32%), Positives = 37/67 (55%)
Query: 541 PASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDD 600
P E + + +EE+ ++EE+EEKE ++ EEEEE + ++ EEE ++E D
Sbjct: 117 PVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176
Query: 601 EEEDRME 607
E R +
Sbjct: 177 TEIQRTQ 183
Score = 39.3 bits (90), Expect = 0.013
Identities = 27/81 (33%), Positives = 44/81 (54%), Gaps = 10/81 (12%)
Query: 537 WSVK-PASSSFGSEAKAQQQEEQGSVNDVK--------EEEKEEKEVLPDQVEEEEENDD 587
W+V P S S+AK + + + N + EE ++ LP + EE EE ++
Sbjct: 69 WAVGLPVKDSGVSQAKIWGKNDLSAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEE 128
Query: 588 Q-EEEEEDEDDEDDEEEDRME 607
+ EEEE++E+ E+DEEE+ E
Sbjct: 129 EVEEEEKEEEKEEDEEEEEKE 149
Score = 37.4 bits (85), Expect = 0.050
Identities = 20/64 (31%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Query: 195 ETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGSEEVDS 254
E E+EE E +EEE++EE+K ++ E++ E ++D + E + K + K EE+D+
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKE-EDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDT 177
Query: 255 HCKK 258
++
Sbjct: 178 EIQR 181
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 53.5 bits (127), Expect = 7e-07
Identities = 32/99 (32%), Positives = 53/99 (53%), Gaps = 11/99 (11%)
Query: 564 VKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENA 623
V + K E E L +Q+ EEEE +++EEEEE+E++E++EEE+ E G Q + +
Sbjct: 283 VDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESG----NQSDRSGSSG 338
Query: 624 RLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTEDP 662
R A+K+ W+ S V+ R P + ++P
Sbjct: 339 RRKAKKK-------WRKDSPWVKPSRKRRKREPPRAKEP 370
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/73 (35%), Positives = 41/73 (56%), Gaps = 11/73 (15%)
Query: 534 SLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEE 593
SLY+ S++K+ E + + EEE+EE+E EEEE +++EEEEE
Sbjct: 271 SLYYDSYSVDERVDSDSKS---EVEALTEQLSEEEEEEEE-------EEEEEEEEEEEEE 320
Query: 594 DEDDEDD-EEEDR 605
+E+DE+ + DR
Sbjct: 321 EEEDEESGNQSDR 333
Score = 30.8 bits (68), Expect = 4.7
Identities = 14/37 (37%), Positives = 23/37 (62%)
Query: 571 EKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRME 607
++ V D E E +Q EEE+E++E++EEE+ E
Sbjct: 280 DERVDSDSKSEVEALTEQLSEEEEEEEEEEEEEEEEE 316
>gi|4757900 calreticulin precursor [Homo sapiens]
Length = 417
Score = 53.5 bits (127), Expect = 7e-07
Identities = 26/70 (37%), Positives = 48/70 (68%), Gaps = 8/70 (11%)
Query: 543 SSSFGSE-------AKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDE 595
+ FG+E A+ Q +++Q +KEEE+++K ++ E++E+++D++E+EEDE
Sbjct: 339 AEEFGNETWGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDE 398
Query: 596 DD-EDDEEED 604
+D E+DEEED
Sbjct: 399 EDKEEDEEED 408
Score = 43.1 bits (100), Expect = 0.001
Identities = 18/62 (29%), Positives = 37/62 (59%)
Query: 537 WSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDED 596
W V A+ + + ++Q + D K +E+EE E D +++E+ +D+E++EEDE+
Sbjct: 347 WGVTKAAEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDDEDKDEDEEDEEDKEEDEE 406
Query: 597 DE 598
++
Sbjct: 407 ED 408
>gi|4505999 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 53.5 bits (127), Expect = 7e-07
Identities = 36/121 (29%), Positives = 61/121 (50%), Gaps = 9/121 (7%)
Query: 507 YTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKE 566
YT NS + G+EA +G+ S AS AK++ E+ +D E
Sbjct: 211 YTGFSSNS--ERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268
Query: 567 EEKEEKEVLPDQV-----EEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAE 621
EE+E+ E ++ EE E +D+++ EE E+D+++EEE+ M P G+E P ++
Sbjct: 269 EEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMV--PGMEGKEEPGSD 326
Query: 622 N 622
+
Sbjct: 327 S 327
>gi|29826282 protein phosphatase 1G [Homo sapiens]
Length = 546
Score = 53.5 bits (127), Expect = 7e-07
Identities = 36/121 (29%), Positives = 61/121 (50%), Gaps = 9/121 (7%)
Query: 507 YTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKE 566
YT NS + G+EA +G+ S AS AK++ E+ +D E
Sbjct: 211 YTGFSSNS--ERGTEAGQVGEPGIPTGEAGPSCSSASDKLPRVAKSKFFEDSEDESDEAE 268
Query: 567 EEKEEKEVLPDQV-----EEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAE 621
EE+E+ E ++ EE E +D+++ EE E+D+++EEE+ M P G+E P ++
Sbjct: 269 EEEEDSEECSEEEDGYSSEEAENEEDEDDTEEAEEDDEEEEEEMMV--PGMEGKEEPGSD 326
Query: 622 N 622
+
Sbjct: 327 S 327
>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
Length = 1812
Score = 52.8 bits (125), Expect = 1e-06
Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 13/129 (10%)
Query: 540 KPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEE------EEE 593
+P S S + Q ++G V + ++EE EE E D EEE+E++D EEE
Sbjct: 219 EPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEE 278
Query: 594 DEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLG 653
+ED+E++ EED E G G E +++ + L+ ++ + DV + L
Sbjct: 279 EEDEEEEGEED--EEGEGDDGYEQISSDEDGI-----ADLERETFKYPNFDVEYTAEDLA 331
Query: 654 RMPGQTEDP 662
+P T DP
Sbjct: 332 SVPPMTYDP 340
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 190 ENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGS 249
E E E E+ + EEED++ED VD I E+ E +D+ + E D + +GD G
Sbjct: 242 EEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEE--EEEDEEEEGEEDEEGEGDD-GY 298
Query: 250 EEVDS 254
E++ S
Sbjct: 299 EQISS 303
>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
Length = 1147
Score = 52.8 bits (125), Expect = 1e-06
Identities = 38/129 (29%), Positives = 62/129 (48%), Gaps = 13/129 (10%)
Query: 540 KPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEE------EEE 593
+P S S + Q ++G V + ++EE EE E D EEE+E++D EEE
Sbjct: 219 EPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEE 278
Query: 594 DEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLG 653
+ED+E++ EED E G G E +++ + L+ ++ + DV + L
Sbjct: 279 EEDEEEEGEED--EEGEGDDGYEQISSDEDGI-----ADLERETFKYPNFDVEYTAEDLA 331
Query: 654 RMPGQTEDP 662
+P T DP
Sbjct: 332 SVPPMTYDP 340
Score = 35.8 bits (81), Expect = 0.15
Identities = 23/65 (35%), Positives = 35/65 (53%), Gaps = 3/65 (4%)
Query: 190 ENSLRETWELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGS 249
E E E E+ + EEED++ED VD I E+ E +D+ + E D + +GD G
Sbjct: 242 EEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEE--EEEDEEEEGEEDEEGEGDD-GY 298
Query: 250 EEVDS 254
E++ S
Sbjct: 299 EQISS 303
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/126 (31%), Positives = 67/126 (53%), Gaps = 6/126 (4%)
Query: 513 NSLVQEGSEASPIGKSPYTLDSLY-WSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEE 571
++L+ G S + K+P T L + P SS G ++ A + E+Q V D + E+
Sbjct: 398 STLLNLGGLTSSVLKTPITSVPLGPLASSPTKSSEGKDSGAAEGEKQ-EVGD-GDCFSEK 455
Query: 572 KEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRG 631
E ++ EEEEE ++ EEEEE+E++E++EEED G F + + + ++ G
Sbjct: 456 VEPAEEEAEEEEEEEEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELEDRPH---EEPG 512
Query: 632 ALQGSA 637
A GS+
Sbjct: 513 AAAGSS 518
Score = 33.9 bits (76), Expect = 0.55
Identities = 32/103 (31%), Positives = 49/103 (47%), Gaps = 21/103 (20%)
Query: 508 TQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEE 567
+ G++S EG E +G D V+PA EA+ +++EE+ EE
Sbjct: 430 SSEGKDSGAAEG-EKQEVGDG----DCFSEKVEPAEE----EAEEEEEEEEA------EE 474
Query: 568 EKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGP 610
E+EE+E EEEEE +D+ + + D+E EDR P
Sbjct: 475 EEEEEE------EEEEEEEDEGCKGLFPSELDEELEDRPHEEP 511
>gi|4503257 death-domain associated protein isoform a [Homo sapiens]
Length = 740
Score = 51.6 bits (122), Expect = 3e-06
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Query: 518 EGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPD 577
+G+ + +LDS AS S ++A+ +E +D +EEE+EE+E
Sbjct: 399 QGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEA 458
Query: 578 QVEEEEENDDQEEEEEDEDDEDDEEEDRM-----EVGPFSTGQES--PTAENARLLAQKR 630
EEEE+ +Q +E +++D+E+DEEE+ + P S+ Q S E + +++
Sbjct: 459 TDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSS 518
Query: 631 GALQGSAWQVSSEDVRWDTFPLGRMPGQT--EDPAELMLENYDTMYLLDQPVLEQRL--E 686
G Q VS + + + ++ E P EL LE + L + +E
Sbjct: 519 GEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDT 578
Query: 687 PSTCKTD 693
PS+ +TD
Sbjct: 579 PSSVETD 585
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 198 ELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGSEEVDSHCK 257
E +E E EEE++EE + ++ EQ E Q+D + + + +A G + S +
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 501
Query: 258 KALSHKELYERARELLVSYEEEQF-------TVLEKFRYLPKAIKAWNNPSPRVECVLAE 310
+S+++ E +++ S E+Q ++L + P +I A +N E L E
Sbjct: 502 --ISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEE 559
>gi|215422388 death-domain associated protein isoform a [Homo
sapiens]
Length = 740
Score = 51.6 bits (122), Expect = 3e-06
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Query: 518 EGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPD 577
+G+ + +LDS AS S ++A+ +E +D +EEE+EE+E
Sbjct: 399 QGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEA 458
Query: 578 QVEEEEENDDQEEEEEDEDDEDDEEEDRM-----EVGPFSTGQES--PTAENARLLAQKR 630
EEEE+ +Q +E +++D+E+DEEE+ + P S+ Q S E + +++
Sbjct: 459 TDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSS 518
Query: 631 GALQGSAWQVSSEDVRWDTFPLGRMPGQT--EDPAELMLENYDTMYLLDQPVLEQRL--E 686
G Q VS + + + ++ E P EL LE + L + +E
Sbjct: 519 GEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDT 578
Query: 687 PSTCKTD 693
PS+ +TD
Sbjct: 579 PSSVETD 585
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 198 ELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGSEEVDSHCK 257
E +E E EEE++EE + ++ EQ E Q+D + + + +A G + S +
Sbjct: 442 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 501
Query: 258 KALSHKELYERARELLVSYEEEQF-------TVLEKFRYLPKAIKAWNNPSPRVECVLAE 310
+S+++ E +++ S E+Q ++L + P +I A +N E L E
Sbjct: 502 --ISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEE 559
>gi|215422366 death-domain associated protein isoform b [Homo
sapiens]
Length = 752
Score = 51.6 bits (122), Expect = 3e-06
Identities = 49/187 (26%), Positives = 86/187 (45%), Gaps = 11/187 (5%)
Query: 518 EGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPD 577
+G+ + +LDS AS S ++A+ +E +D +EEE+EE+E
Sbjct: 411 QGTSSHSADTPEASLDSGEGPSGMASQGCPSASRAETDDEDDEESDEEEEEEEEEEEEEA 470
Query: 578 QVEEEEENDDQEEEEEDEDDEDDEEEDRM-----EVGPFSTGQES--PTAENARLLAQKR 630
EEEE+ +Q +E +++D+E+DEEE+ + P S+ Q S E + +++
Sbjct: 471 TDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQISNEKNLEPGKQISRSS 530
Query: 631 GALQGSAWQVSSEDVRWDTFPLGRMPGQT--EDPAELMLENYDTMYLLDQPVLEQRL--E 686
G Q VS + + + ++ E P EL LE + L + +E
Sbjct: 531 GEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEEESPVSQLFELEIEALPLDT 590
Query: 687 PSTCKTD 693
PS+ +TD
Sbjct: 591 PSSVETD 597
Score = 31.6 bits (70), Expect = 2.8
Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 9/120 (7%)
Query: 198 ELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKGSEEVDSHCK 257
E +E E EEE++EE + ++ EQ E Q+D + + + +A G + S +
Sbjct: 454 ESDEEEEEEEEEEEEEATDSEEEEDLEQMQEGQEDDEEEDEEEEAAAGKDGDKSPMSSLQ 513
Query: 258 KALSHKELYERARELLVSYEEEQF-------TVLEKFRYLPKAIKAWNNPSPRVECVLAE 310
+S+++ E +++ S E+Q ++L + P +I A +N E L E
Sbjct: 514 --ISNEKNLEPGKQISRSSGEQQNKGRIVSPSLLSEEPLAPSSIDAESNGEQPEELTLEE 571
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 51.6 bits (122), Expect = 3e-06
Identities = 21/40 (52%), Positives = 35/40 (87%)
Query: 565 KEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEED 604
KEEE+EE+E ++ E+EEE +++EEEEE+E++E++EEE+
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 50.8 bits (120), Expect = 4e-06
Identities = 21/46 (45%), Positives = 36/46 (78%)
Query: 558 QGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEE 603
Q N +EEE+EE++ ++ +EEEE +++EEEEE+E++E++EEE
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 47.4 bits (111), Expect = 5e-05
Identities = 20/54 (37%), Positives = 38/54 (70%)
Query: 556 EEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVG 609
+ Q + + +EEE+E++E + EEEEE +++EEEEE+E++E++E + +G
Sbjct: 726 QPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALG 779
Score = 47.0 bits (110), Expect = 6e-05
Identities = 20/49 (40%), Positives = 35/49 (71%)
Query: 552 AQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDD 600
A Q + + +EEE++E+E D+ EEEEE +++EEEEE+E++E++
Sbjct: 723 APVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 771
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/50 (42%), Positives = 36/50 (72%), Gaps = 6/50 (12%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDE 598
+A +++EE+ ++ +EEE EE+E EEEEE +++EEEEE+E++E
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEE------EEEEEEEEEEEEEEEEEEE 771
Score = 44.7 bits (104), Expect = 3e-04
Identities = 22/58 (37%), Positives = 35/58 (60%)
Query: 580 EEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSA 637
+EEEE ++++EEEE+ED+E++EEE+ E +E A A L + G GS+
Sbjct: 732 KEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSS 789
Score = 39.7 bits (91), Expect = 0.010
Identities = 16/34 (47%), Positives = 26/34 (76%)
Query: 574 VLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRME 607
V P +EEE +++E+EEE+E+DE++EEE+ E
Sbjct: 725 VQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEE 758
Score = 39.3 bits (90), Expect = 0.013
Identities = 22/70 (31%), Positives = 37/70 (52%), Gaps = 6/70 (8%)
Query: 525 IGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEE 584
+G S L + + P + + +++EE + EEE+EE+E EEEEE
Sbjct: 708 VGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEE------EEEEE 761
Query: 585 NDDQEEEEED 594
+++EEEEE+
Sbjct: 762 EEEEEEEEEE 771
Score = 37.7 bits (86), Expect = 0.038
Identities = 21/68 (30%), Positives = 34/68 (50%)
Query: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQG 635
P Q + + +++EEEE++E++E+DEEE+ E +E E A G + G
Sbjct: 724 PVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLG 783
Query: 636 SAWQVSSE 643
SSE
Sbjct: 784 PRSGSSSE 791
>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
Length = 539
Score = 51.6 bits (122), Expect = 3e-06
Identities = 28/107 (26%), Positives = 57/107 (53%), Gaps = 8/107 (7%)
Query: 504 CSIYTQSGENSLV---QEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGS 560
C YT +++ + Q E +G +T +YW V+ + + + +EE+G
Sbjct: 334 CVTYTSLYKSAYLHPQQFDCEPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEG- 392
Query: 561 VNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRME 607
+EEE+EE+ D ++ E ++D+E ++E++E++EEE+ +E
Sbjct: 393 ----EEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEEEEEEEVLE 435
Score = 35.0 bits (79), Expect = 0.25
Identities = 15/32 (46%), Positives = 22/32 (68%)
Query: 578 QVEEEEENDDQEEEEEDEDDEDDEEEDRMEVG 609
+VE E E ++EEE DE++E +EEE+ E G
Sbjct: 371 EVEVEREGWSEDEEEGDEEEEGEEEEEEEEAG 402
Score = 32.7 bits (73), Expect = 1.2
Identities = 13/32 (40%), Positives = 23/32 (71%)
Query: 578 QVEEEEENDDQEEEEEDEDDEDDEEEDRMEVG 609
+VE E ++D+EE +E+E+ E++EEE+ G
Sbjct: 373 EVEREGWSEDEEEGDEEEEGEEEEEEEEAGYG 404
Score = 32.0 bits (71), Expect = 2.1
Identities = 18/58 (31%), Positives = 31/58 (53%), Gaps = 3/58 (5%)
Query: 197 WELEEFREGIEEEDQEEDKNIVVDDITEQKPEPQDDGK---STESDVKADGDSKGSEE 251
WE+E REG E+++E D+ ++ E++ DG T+ D ++ GD + EE
Sbjct: 370 WEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETDEDEESLGDEEEEEE 427
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 51.2 bits (121), Expect = 3e-06
Identities = 29/82 (35%), Positives = 50/82 (60%), Gaps = 8/82 (9%)
Query: 567 EEKEEKEVLPDQVEEE--EENDDQEEEEEDEDDEDDEEEDRMEVGPFSTG--QESPTAEN 622
EE+ E+E ++++EE EE +++EEEEE+E++E++EEE++ GP +G E + E
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEE 167
Query: 623 ARLL----AQKRGALQGSAWQV 640
+ L + + AL WQV
Sbjct: 168 DQALEEWVSSETSALPRPRWQV 189
Score = 33.5 bits (75), Expect = 0.72
Identities = 32/131 (24%), Positives = 57/131 (43%), Gaps = 17/131 (12%)
Query: 491 GLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEA 550
GLPD E L S QSG + + S+ I S ++ F ++A
Sbjct: 10 GLPDLGTESLFS--SPEEQSGAVAATEASSDID-IATSELSVTVTGDGSDSRDGGFPNDA 66
Query: 551 KAQQQ--EEQGSVNDVKEEEKEEKE------------VLPDQVEEEEENDDQEEEEEDED 596
+ + +++ + D++ E E+ E L + E E E +D+E +EE +
Sbjct: 67 STENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREEEDEEIQEEGGE 126
Query: 597 DEDDEEEDRME 607
+E++EEE+ E
Sbjct: 127 EEEEEEEEEEE 137
Score = 33.5 bits (75), Expect = 0.72
Identities = 15/42 (35%), Positives = 27/42 (64%)
Query: 547 GSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQ 588
G E +++E++ + EEE+EE+E ++ EEEEE ++Q
Sbjct: 107 GEEETEREEEDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQ 148
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 50.8 bits (120), Expect = 4e-06
Identities = 23/40 (57%), Positives = 31/40 (77%)
Query: 565 KEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEED 604
+EEE+EE V ++ EEEEE D++EEEE + DEDDEE+D
Sbjct: 8 EEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDD 47
Score = 50.1 bits (118), Expect = 7e-06
Identities = 24/52 (46%), Positives = 37/52 (71%), Gaps = 5/52 (9%)
Query: 564 VKEEEKEEKEVLPDQVEEEEENDDQEEEEE-----DEDDEDDEEEDRMEVGP 610
+++EE+EE+E++ + EEEEE + EEEEE DEDDE+D++E + GP
Sbjct: 5 LRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDEGVLGRGP 56
Score = 37.0 bits (84), Expect = 0.066
Identities = 19/48 (39%), Positives = 28/48 (58%)
Query: 550 AKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDD 597
A + EE+ V EE+EE+E D+ EEEE E++EED+D+
Sbjct: 2 ASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEVEAADEDDEEDDDE 49
Score = 33.1 bits (74), Expect = 0.95
Identities = 15/33 (45%), Positives = 23/33 (69%)
Query: 576 PDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
P + EEEEE + EEE+E++E+ +EE+ EV
Sbjct: 4 PLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEEV 36
Score = 32.0 bits (71), Expect = 2.1
Identities = 15/38 (39%), Positives = 24/38 (63%)
Query: 571 EKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
EKE + + +EEEE ++E EEE E +E+D+ + V
Sbjct: 483 EKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHMEYCRV 520
Score = 31.2 bits (69), Expect = 3.6
Identities = 14/34 (41%), Positives = 24/34 (70%)
Query: 570 EEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEE 603
E++ V + EEEEE +++ EEE ++++EDD E
Sbjct: 483 EKEGVQWEAKEEEEEYEEEGEEEGEKEEEDDHME 516
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 50.8 bits (120), Expect = 4e-06
Identities = 24/60 (40%), Positives = 37/60 (61%), Gaps = 6/60 (10%)
Query: 551 KAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGP 610
K + +EE+ D +E++E + EE EE +++EEEEEDEDD+D+ EE+ E P
Sbjct: 517 KVEAEEEKAKSGDETNKEEDEDD------EEAEEEEEEEEEEEDEDDDDNNEEEEFECYP 570
Score = 47.8 bits (112), Expect = 4e-05
Identities = 19/42 (45%), Positives = 32/42 (76%)
Query: 563 DVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEED 604
++K E +EEK D+ +EE+ DD+E EEE+E++E++E+ED
Sbjct: 515 NIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEEEEEEDED 556
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/99 (28%), Positives = 50/99 (50%), Gaps = 8/99 (8%)
Query: 512 ENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEE 571
E+ + ++ + +G L+S+ P S E ++ E+ +++D ++
Sbjct: 456 EDEIERKENIKPSLGSKKNLLESI-----PTHSDQEKEVNIKKPEDNENLDDKDDDTTRV 510
Query: 572 KEVLPDQVEEEEE---NDDQEEEEEDEDDEDDEEEDRME 607
E L +VE EEE + D+ +EEDEDDE+ EEE+ E
Sbjct: 511 DESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEEEEEEE 549
Score = 38.1 bits (87), Expect = 0.029
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 1/47 (2%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDE 595
E KA+ +E D +EE EE+E ++ EE+E++DD EEEE E
Sbjct: 522 EEKAKSGDETNKEEDEDDEEAEEEEE-EEEEEEDEDDDDNNEEEEFE 567
Score = 34.3 bits (77), Expect = 0.42
Identities = 13/46 (28%), Positives = 27/46 (58%)
Query: 572 KEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQES 617
K L + E +++EEE+++++ ED+ E+ E+ PF +E+
Sbjct: 266 KTELKEDSSSSEAEEEEEEEDDEKEKEDNSSEEEEEIEPFPEEREN 311
Score = 33.9 bits (76), Expect = 0.55
Identities = 19/63 (30%), Positives = 35/63 (55%), Gaps = 6/63 (9%)
Query: 556 EEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQ 615
+E S ++ +EEE+EE + E+E+E++ EEEEE E ++ E ++ F +
Sbjct: 270 KEDSSSSEAEEEEEEEDD------EKEKEDNSSEEEEEIEPFPEERENFLQQLYKFMEDR 323
Query: 616 ESP 618
+P
Sbjct: 324 GTP 326
>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 50.4 bits (119), Expect = 6e-06
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 512 ENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKA-----QQQEEQGSVNDVKE 566
E +Q +E + G+ S + PA SS E + +++EE+ V++ +
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 567 EEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENAR 624
+ +EE++ L + EEEE+ E + D+ D DDE++ +E +E PT E+ +
Sbjct: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVK 1342
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 5/132 (3%)
Query: 495 EEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSE---AK 551
EE+E+ R+ QS E QE E P + ++ A K
Sbjct: 1271 EEEEEKPRVSEEQRQSEEEQ--QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328
Query: 552 AQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPF 611
++ EEQ + DVKEE ++ L +++ E +EE E + +E+ D V
Sbjct: 1329 KKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQ 1388
Query: 612 STGQESPTAENA 623
G E E++
Sbjct: 1389 MAGSEDDHEEDS 1400
Score = 32.3 bits (72), Expect = 1.6
Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 10/125 (8%)
Query: 547 GSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRM 606
G + K Q+ EE E +E LP++ +EEEE + EE E+ ++ED +
Sbjct: 1199 GRKPKIQESEET--------VEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVP 1250
Query: 607 EVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTEDPAELM 666
P + T + ++ + S Q SE+ + + P + ED A
Sbjct: 1251 AASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE--PEPEEEEDAAAET 1308
Query: 667 LENYD 671
+N D
Sbjct: 1309 AQNDD 1313
Score = 31.6 bits (70), Expect = 2.8
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 20/110 (18%)
Query: 563 DVKEEEKEEKEVLPD--------------QVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
D +EEE++E E+ P Q + ++ D+EE+EE +D +D + +
Sbjct: 1068 DEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSL 1127
Query: 609 GPFSTGQESP-TAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPG 657
+ SP + + L +K+G +G S + + W P GR PG
Sbjct: 1128 LRKRDVKNSPLEPDTSTPLKKKKGWPKGK----SRKPIHWKKRP-GRKPG 1172
Score = 30.4 bits (67), Expect = 6.1
Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 14/138 (10%)
Query: 477 SPQLLRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLY 536
SP+ L+ + LP E + +++S E +E SP SP L
Sbjct: 954 SPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSE----EEEEPESPRSSSPPIL---- 1005
Query: 537 WSVKPA---SSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEE-ENDDQEEEE 592
KP F + ++ + + + V E E EVL + E+ + E E
Sbjct: 1006 --TKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEP 1063
Query: 593 EDEDDEDDEEEDRMEVGP 610
E DE++EEED E+ P
Sbjct: 1064 TFEIDEEEEEEDENELFP 1081
Score = 30.4 bits (67), Expect = 6.1
Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 30/136 (22%)
Query: 538 SVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKE-------------------EKEVLPDQ 578
+V+P E + +++E Q + +E E+E E E +
Sbjct: 1210 TVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPE 1269
Query: 579 VEEEEEN---DDQEEEEEDEDDE-----DDEEEDRMEVGPFSTGQESPTAENARLLAQKR 630
VEEEEE +++ + E+E E +EEED + ++ ++ L + K+
Sbjct: 1270 VEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKK 1329
Query: 631 GALQGSAWQVSSEDVR 646
L+ Q + EDV+
Sbjct: 1330 KELEE---QPTREDVK 1342
>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 50.4 bits (119), Expect = 6e-06
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 512 ENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKA-----QQQEEQGSVNDVKE 566
E +Q +E + G+ S + PA SS E + +++EE+ V++ +
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 567 EEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENAR 624
+ +EE++ L + EEEE+ E + D+ D DDE++ +E +E PT E+ +
Sbjct: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVK 1342
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 5/132 (3%)
Query: 495 EEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSE---AK 551
EE+E+ R+ QS E QE E P + ++ A K
Sbjct: 1271 EEEEEKPRVSEEQRQSEEEQ--QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328
Query: 552 AQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPF 611
++ EEQ + DVKEE ++ L +++ E +EE E + +E+ D V
Sbjct: 1329 KKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQ 1388
Query: 612 STGQESPTAENA 623
G E E++
Sbjct: 1389 MAGSEDDHEEDS 1400
Score = 32.3 bits (72), Expect = 1.6
Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 10/125 (8%)
Query: 547 GSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRM 606
G + K Q+ EE E +E LP++ +EEEE + EE E+ ++ED +
Sbjct: 1199 GRKPKIQESEET--------VEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVP 1250
Query: 607 EVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTEDPAELM 666
P + T + ++ + S Q SE+ + + P + ED A
Sbjct: 1251 AASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE--PEPEEEEDAAAET 1308
Query: 667 LENYD 671
+N D
Sbjct: 1309 AQNDD 1313
Score = 31.6 bits (70), Expect = 2.8
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 20/110 (18%)
Query: 563 DVKEEEKEEKEVLPD--------------QVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
D +EEE++E E+ P Q + ++ D+EE+EE +D +D + +
Sbjct: 1068 DEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSL 1127
Query: 609 GPFSTGQESP-TAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPG 657
+ SP + + L +K+G +G S + + W P GR PG
Sbjct: 1128 LRKRDVKNSPLEPDTSTPLKKKKGWPKGK----SRKPIHWKKRP-GRKPG 1172
Score = 30.4 bits (67), Expect = 6.1
Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 14/138 (10%)
Query: 477 SPQLLRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLY 536
SP+ L+ + LP E + +++S E +E SP SP L
Sbjct: 954 SPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSE----EEEEPESPRSSSPPIL---- 1005
Query: 537 WSVKPA---SSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEE-ENDDQEEEE 592
KP F + ++ + + + V E E EVL + E+ + E E
Sbjct: 1006 --TKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEP 1063
Query: 593 EDEDDEDDEEEDRMEVGP 610
E DE++EEED E+ P
Sbjct: 1064 TFEIDEEEEEEDENELFP 1081
Score = 30.4 bits (67), Expect = 6.1
Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 30/136 (22%)
Query: 538 SVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKE-------------------EKEVLPDQ 578
+V+P E + +++E Q + +E E+E E E +
Sbjct: 1210 TVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPE 1269
Query: 579 VEEEEEN---DDQEEEEEDEDDE-----DDEEEDRMEVGPFSTGQESPTAENARLLAQKR 630
VEEEEE +++ + E+E E +EEED + ++ ++ L + K+
Sbjct: 1270 VEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKK 1329
Query: 631 GALQGSAWQVSSEDVR 646
L+ Q + EDV+
Sbjct: 1330 KELEE---QPTREDVK 1342
>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
[Homo sapiens]
Length = 2004
Score = 50.4 bits (119), Expect = 6e-06
Identities = 31/118 (26%), Positives = 58/118 (49%), Gaps = 5/118 (4%)
Query: 512 ENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSEAKA-----QQQEEQGSVNDVKE 566
E +Q +E + G+ S + PA SS E + +++EE+ V++ +
Sbjct: 1225 EEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPEVEEEEEKPRVSEEQR 1284
Query: 567 EEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQESPTAENAR 624
+ +EE++ L + EEEE+ E + D+ D DDE++ +E +E PT E+ +
Sbjct: 1285 QSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKKKELEEQPTREDVK 1342
Score = 35.8 bits (81), Expect = 0.15
Identities = 32/132 (24%), Positives = 52/132 (39%), Gaps = 5/132 (3%)
Query: 495 EEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLYWSVKPASSSFGSE---AK 551
EE+E+ R+ QS E QE E P + ++ A K
Sbjct: 1271 EEEEEKPRVSEEQRQSEEEQ--QELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTK 1328
Query: 552 AQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRMEVGPF 611
++ EEQ + DVKEE ++ L +++ E +EE E + +E+ D V
Sbjct: 1329 KKELEEQPTREDVKEEPGVQESFLDANMQKSREKIKDKEETELDSEEEQPSHDTSVVSEQ 1388
Query: 612 STGQESPTAENA 623
G E E++
Sbjct: 1389 MAGSEDDHEEDS 1400
Score = 32.3 bits (72), Expect = 1.6
Identities = 30/125 (24%), Positives = 51/125 (40%), Gaps = 10/125 (8%)
Query: 547 GSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDEEEDRM 606
G + K Q+ EE E +E LP++ +EEEE + EE E+ ++ED +
Sbjct: 1199 GRKPKIQESEET--------VEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVP 1250
Query: 607 EVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQTEDPAELM 666
P + T + ++ + S Q SE+ + + P + ED A
Sbjct: 1251 AASPADSSNSPETETKEPEVEEEEEKPRVSEEQRQSEEEQQELEE--PEPEEEEDAAAET 1308
Query: 667 LENYD 671
+N D
Sbjct: 1309 AQNDD 1313
Score = 31.6 bits (70), Expect = 2.8
Identities = 28/110 (25%), Positives = 49/110 (44%), Gaps = 20/110 (18%)
Query: 563 DVKEEEKEEKEVLPD--------------QVEEEEENDDQEEEEEDEDDEDDEEEDRMEV 608
D +EEE++E E+ P Q + ++ D+EE+EE +D +D + +
Sbjct: 1068 DEEEEEEDENELFPREYFRRLSSQDVLRCQSSSKRKSKDEEEDEESDDADDTPILKPVSL 1127
Query: 609 GPFSTGQESP-TAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPG 657
+ SP + + L +K+G +G S + + W P GR PG
Sbjct: 1128 LRKRDVKNSPLEPDTSTPLKKKKGWPKGK----SRKPIHWKKRP-GRKPG 1172
Score = 30.4 bits (67), Expect = 6.1
Identities = 35/138 (25%), Positives = 55/138 (39%), Gaps = 14/138 (10%)
Query: 477 SPQLLRIIFKAMGQGLPDEEQEKLLRICSIYTQSGENSLVQEGSEASPIGKSPYTLDSLY 536
SP+ L+ + LP E + +++S E +E SP SP L
Sbjct: 954 SPEALKCRLTEGSERLPRRYSEGDRAVLRGFSESSE----EEEEPESPRSSSPPIL---- 1005
Query: 537 WSVKPA---SSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEE-ENDDQEEEE 592
KP F + ++ + + + V E E EVL + E+ + E E
Sbjct: 1006 --TKPTLKRKKPFLHRRRRVRKRKHHNSSVVTETISETTEVLDEPFEDSDSERPMPRLEP 1063
Query: 593 EDEDDEDDEEEDRMEVGP 610
E DE++EEED E+ P
Sbjct: 1064 TFEIDEEEEEEDENELFP 1081
Score = 30.4 bits (67), Expect = 6.1
Identities = 30/136 (22%), Positives = 56/136 (41%), Gaps = 30/136 (22%)
Query: 538 SVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKE-------------------EKEVLPDQ 578
+V+P E + +++E Q + +E E+E E E +
Sbjct: 1210 TVEPKEDMPLPEERKEEEEMQAEAEEAEEGEEEDAASSEVPAASPADSSNSPETETKEPE 1269
Query: 579 VEEEEEN---DDQEEEEEDEDDE-----DDEEEDRMEVGPFSTGQESPTAENARLLAQKR 630
VEEEEE +++ + E+E E +EEED + ++ ++ L + K+
Sbjct: 1270 VEEEEEKPRVSEEQRQSEEEQQELEEPEPEEEEDAAAETAQNDDHDADDEDDGHLESTKK 1329
Query: 631 GALQGSAWQVSSEDVR 646
L+ Q + EDV+
Sbjct: 1330 KELEE---QPTREDVK 1342
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 50.4 bits (119), Expect = 6e-06
Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 4/85 (4%)
Query: 527 KSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSV----NDVKEEEKEEKEVLPDQVEEE 582
+ P+ + + SV S G+E +++E++G ND +E EE E + EEE
Sbjct: 75 RKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEE 134
Query: 583 EENDDQEEEEEDEDDEDDEEEDRME 607
E +D++++E+ ED ED+EEE+ E
Sbjct: 135 IEEEDEDDDEDGEDVEDEEEEEEEE 159
Score = 45.4 bits (106), Expect = 2e-04
Identities = 18/55 (32%), Positives = 38/55 (69%)
Query: 547 GSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQEEEEEDEDDEDDE 601
G E + ++ ++ +++EE++++ E D +EEEE +++EEEEE+E++ED +
Sbjct: 118 GDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
Score = 42.4 bits (98), Expect = 0.002
Identities = 37/140 (26%), Positives = 69/140 (49%), Gaps = 13/140 (9%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEEENDDQE---------EEEEDEDDED 599
E + + +++ DV++EE+EE+E ++ EEEEEN+D + ++ E +D+ +
Sbjct: 134 EIEEEDEDDDEDGEDVEDEEEEEEE--EEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNN 191
Query: 600 DEEEDRMEVGPFSTGQESPTAENARLLAQKRGALQGSAWQVSSEDVRWDTFPLGRMPGQT 659
DE ++ E+ S AE+A A+ + + S ED LGR +
Sbjct: 192 DEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNT-SNSLEDDSDKNENLGRKSELS 250
Query: 660 ED-PAELMLENYDTMYLLDQ 678
D ++++ E D++ LL Q
Sbjct: 251 LDLDSDVVRETVDSLKLLAQ 270
Score = 38.5 bits (88), Expect = 0.023
Identities = 20/93 (21%), Positives = 45/93 (48%)
Query: 524 PIGKSPYTLDSLYWSVKPASSSFGSEAKAQQQEEQGSVNDVKEEEKEEKEVLPDQVEEEE 583
P+ K T D P F +A + +E + ++ +++E++ + E+ +
Sbjct: 56 PLAKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND 115
Query: 584 ENDDQEEEEEDEDDEDDEEEDRMEVGPFSTGQE 616
E D++EE+E+ D E++EE + + G++
Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDGED 148
Score = 30.8 bits (68), Expect = 4.7
Identities = 14/54 (25%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 547 GSEAKAQQQEEQGSVNDVKEEEKEEKEV--LPDQVEEEEENDDQEEEEEDEDDE 598
G + + +++EE+ + +EEE E+ ++ ++ ++ E DD +E D DE
Sbjct: 146 GEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDE 199
Score = 30.4 bits (67), Expect = 6.1
Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 5/67 (7%)
Query: 194 RETWELEEFRE-----GIEEEDQEEDKNIVVDDITEQKPEPQDDGKSTESDVKADGDSKG 248
+E E EE+ E G E+E+ EE ++I E+ + +DG+ E + + + + +
Sbjct: 102 KEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEE 161
Query: 249 SEEVDSH 255
EE + +
Sbjct: 162 EEEEEEN 168
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 50.4 bits (119), Expect = 6e-06
Identities = 28/64 (43%), Positives = 39/64 (60%), Gaps = 9/64 (14%)
Query: 549 EAKAQQQEEQGSVNDVKEEEKEEKEVL---------PDQVEEEEENDDQEEEEEDEDDED 599
EA Q++E QG + ++EE+EE+E + P VEEEE EEEEE+E+DE+
Sbjct: 623 EAANQREEGQGEQGEEEDEEEEEEEDVAENRYFEMGPPDVEEEEGGGQGEEEEEEEEDEE 682
Query: 600 DEEE 603
EEE
Sbjct: 683 AEEE 686
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,876,259
Number of Sequences: 37866
Number of extensions: 1677647
Number of successful extensions: 44720
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 745
Number of HSP's successfully gapped in prelim test: 364
Number of HSP's that attempted gapping in prelim test: 13614
Number of HSP's gapped (non-prelim): 13559
length of query: 734
length of database: 18,247,518
effective HSP length: 110
effective length of query: 624
effective length of database: 14,082,258
effective search space: 8787328992
effective search space used: 8787328992
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.