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Search of human proteins with 6912492
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912492 mitogen-activated protein kinase 8 interacting
protein 2 isoform 1 [Homo sapiens]
(824 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912492 mitogen-activated protein kinase 8 interacting protei... 1700 0.0
gi|7706537 mitogen-activated protein kinase 8 interacting protei... 1581 0.0
gi|4885433 mitogen-activated protein kinase 8 interacting protei... 414 e-115
gi|239740950 PREDICTED: similar to mitogen-activated protein kin... 352 1e-96
gi|169211037 PREDICTED: similar to mitogen-activated protein kin... 335 1e-91
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 64 4e-10
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 1e-08
gi|122937321 UNC homeobox [Homo sapiens] 59 2e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 58 4e-08
gi|151101459 SAPS domain family, member 1 [Homo sapiens] 57 7e-08
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 56 2e-07
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 56 2e-07
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens] 56 2e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 55 2e-07
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 55 3e-07
gi|239753314 PREDICTED: similar to RIKEN cDNA C230030N03 [Homo s... 55 3e-07
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 55 3e-07
gi|38176300 nestin [Homo sapiens] 55 3e-07
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 55 3e-07
gi|210032580 SET domain containing 1B [Homo sapiens] 55 3e-07
gi|189181750 human immunodeficiency virus type I enhancer bindin... 54 5e-07
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 54 6e-07
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 54 8e-07
gi|55741677 SET domain containing 1A [Homo sapiens] 54 8e-07
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] 54 8e-07
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] 54 8e-07
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] 54 8e-07
gi|116089331 human immunodeficiency virus type I enhancer bindin... 54 8e-07
gi|166795264 AE binding protein 2 isoform b [Homo sapiens] 53 1e-06
gi|166795262 AE binding protein 2 isoform a [Homo sapiens] 53 1e-06
>gi|6912492 mitogen-activated protein kinase 8 interacting protein 2
isoform 1 [Homo sapiens]
Length = 824
Score = 1700 bits (4403), Expect = 0.0
Identities = 824/824 (100%), Positives = 824/824 (100%)
Query: 1 MADRAEMFSLSTFHSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSL 60
MADRAEMFSLSTFHSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSL
Sbjct: 1 MADRAEMFSLSTFHSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSL 60
Query: 61 SLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPA 120
SLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPA
Sbjct: 61 SLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPA 120
Query: 121 PGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALR 180
PGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALR
Sbjct: 121 PGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALR 180
Query: 181 ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGR 240
ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGR
Sbjct: 181 ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGR 240
Query: 241 GGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEA 300
GGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEA
Sbjct: 241 GGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEA 300
Query: 301 SSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMIS 360
SSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMIS
Sbjct: 301 SSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMIS 360
Query: 361 EGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPP 420
EGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPP
Sbjct: 361 EGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPP 420
Query: 421 APAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEE 480
APAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEE
Sbjct: 421 APAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEE 480
Query: 481 DAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDS 540
DAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDS
Sbjct: 481 DAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDS 540
Query: 541 GGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLV 600
GGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLV
Sbjct: 541 GGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLV 600
Query: 601 NGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYA 660
NGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYA
Sbjct: 601 NGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYA 660
Query: 661 HAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLR 720
HAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLR
Sbjct: 661 HAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLR 720
Query: 721 PPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLS 780
PPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLS
Sbjct: 721 PPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLS 780
Query: 781 RFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824
RFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE
Sbjct: 781 RFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824
>gi|7706537 mitogen-activated protein kinase 8 interacting protein 2
isoform 2 [Homo sapiens]
Length = 797
Score = 1581 bits (4094), Expect = 0.0
Identities = 767/768 (99%), Positives = 768/768 (100%)
Query: 57 KDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS 116
+DSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS
Sbjct: 30 QDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS 89
Query: 117 EAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP 176
EAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP
Sbjct: 90 EAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP 149
Query: 177 EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRS 236
EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRS
Sbjct: 150 EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRS 209
Query: 237 SGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNS 296
SGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNS
Sbjct: 210 SGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNS 269
Query: 297 IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS 356
IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS
Sbjct: 270 IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS 329
Query: 357 RMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA 416
RMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA
Sbjct: 330 RMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA 389
Query: 417 PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD 476
PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD
Sbjct: 390 PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD 449
Query: 477 EEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDS 536
EEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDS
Sbjct: 450 EEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDS 509
Query: 537 EEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLF 596
EEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLF
Sbjct: 510 EEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLF 569
Query: 597 SCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFP 656
SCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFP
Sbjct: 570 SCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFP 629
Query: 657 AFYAHAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLT 716
AFYAHAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLT
Sbjct: 630 AFYAHAVPGPAKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLT 689
Query: 717 VHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKH 776
VHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKH
Sbjct: 690 VHLRPPASCDLEISLRGVKLSLSGGGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKH 749
Query: 777 PLLSRFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824
PLLSRFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE
Sbjct: 750 PLLSRFACHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 797
>gi|4885433 mitogen-activated protein kinase 8 interacting protein 1
[Homo sapiens]
Length = 711
Score = 414 bits (1065), Expect = e-115
Identities = 261/641 (40%), Positives = 343/641 (53%), Gaps = 84/641 (13%)
Query: 217 PGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGS-DSEDAGGARLGRMISSISETE 275
PG P ++ G E RG +S + PGS D+ + + ++
Sbjct: 122 PGAGPPKAESGQEP-------ASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQ 174
Query: 276 LELSSDGGSSSSGRSSHLTNSIEEASSP--ASEPEPPREPPRRPAFLPVGPDDTNSEYES 333
L+++ S G+ + + +SSP E PP E LP +S
Sbjct: 175 DTLNNN----SLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPP---------QS 221
Query: 334 GSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQD 393
G D DSP C + P G P +P GG
Sbjct: 222 GPAPTTDRGTSTDSP-------------------CRRSTATQMAPPGGPPAAPPGGRGHS 262
Query: 394 SQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAP 453
+D V L E + P P P A+P +R +++ + P
Sbjct: 263 HRD--RIHYQADVRLEATEEIYLTPVQRP----PDAAEPTSAFLPPTESRMSVS---SDP 313
Query: 454 GRAARP---GRACSAACSEEEDEEDDEEEEDAEDSAGS-PGGRGTGPSAPR------DAS 503
AA P GR + EEE + E AE G G G P PR ++
Sbjct: 314 DPAAYPSTAGRPHPSISEEEEGFDCLSSPERAEPPGGGWRGSLGEPPPPPRASLSSDTSA 373
Query: 504 LVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSG-----------------GEASE 546
L YD+VKYTLVVDEH QLELVSLR C G + E DS GE E
Sbjct: 374 LSYDSVKYTLVVDEHAQLELVSLRPCFG-DYSDESDSATVYDNCASVSSPYESAIGEEYE 432
Query: 547 EEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEERE 606
E +S D++PD PD+ FSKKFLNVF++ SRSSS ESFGLFSC++NGEE+E
Sbjct: 433 EAPRPQ--PPACLSEDSTPDEPDVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQE 490
Query: 607 QTHRAVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGP 666
QTHRA+FRF+PRH DELEL+VDDP+LVE + +D+W+ +NMRTG RGVFPA+YA V
Sbjct: 491 QTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKE 550
Query: 667 AKDLLGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCD 726
+ + ++ WV++F V+FLGSV+VP H+GN +LCAAMQKIAT R+LTVH PP+SC
Sbjct: 551 PEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCV 610
Query: 727 LEISLRGVKLSLSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFA 783
LEIS+RGVK+ + + +CSHFFQ+KNISFCG HP+N+ YFGFITKHP RFA
Sbjct: 611 LEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFA 670
Query: 784 CHVFVSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824
CHVFVS++S + +A+SVGRAF ++Y++ + Y CPTEDIYLE
Sbjct: 671 CHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE 711
Score = 92.0 bits (227), Expect = 2e-18
Identities = 104/345 (30%), Positives = 143/345 (41%), Gaps = 66/345 (19%)
Query: 14 HSLSPPGCRPPQDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSEQPHPICS 73
H SPP R DISLEEF+DEDLSEITD+CG+ L KD+LSL R + + +
Sbjct: 26 HIASPPNFRLTHDISLEEFEDEDLSEITDECGISLQC------KDTLSL-RPPRAGLLSA 78
Query: 74 --------FQDDFQEFEMIDDNEE----EDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAP 121
Q + + ++ID + EDDE++++EE G G + G E +
Sbjct: 79 GGGGAGSRLQAEMLQMDLIDATGDTPGAEDDEEDDDEERAARRPGAGPPKAESGQEPASR 138
Query: 122 GPLIPSPSVEEP------HKHRPTTLRL--TTLGAQDSLNNNGGFDLVRPASWQETALCS 173
G + P RPTTL L +QD+LNNN L + SWQ+ S
Sbjct: 139 GQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNN---SLGKKHSWQDRVSRS 195
Query: 174 PAP----------------EALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPA- 216
+P + L GP P TD G SP R + P PPA
Sbjct: 196 SSPLKTGEQTPPHEHICLSDELPPQSGPAPTTDRGT-STDSPCRRSTATQMAPPGGPPAA 254
Query: 217 -PGGTSPSSDPGI--EADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISE 273
PGG S I +AD+R + + + +P DA A +E
Sbjct: 255 PPGGRGHSHRDRIHYQADVRLEA--------TEEIYLTPVQRPPDA--AEPTSAFLPPTE 304
Query: 274 TELELSSD----GGSSSSGRSSHLTNSIEEASSPASEPEPPREPP 314
+ + +SSD S++GR + EE S PE EPP
Sbjct: 305 SRMSVSSDPDPAAYPSTAGRPHPSISEEEEGFDCLSSPE-RAEPP 348
>gi|239740950 PREDICTED: similar to mitogen-activated protein kinase
8 interacting protein 1 [Homo sapiens]
Length = 442
Score = 352 bits (902), Expect = 1e-96
Identities = 179/337 (53%), Positives = 233/337 (69%), Gaps = 31/337 (9%)
Query: 512 TLVVDEHTQLELVSLRRCAGLGHDSEEDSG---------------------GEASEEEAG 550
TL+VDEH QLELVSLR C G + E DS EAS +
Sbjct: 113 TLLVDEHAQLELVSLRPCFG-DYSDESDSAIVYDNCVSVSSPYESAIGEEYEEASRPQPP 171
Query: 551 AALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHR 610
A L S D++PD PD+ FSKKFLN+F++ SRSSS ESFGLFSC++N EE+EQTHR
Sbjct: 172 ACL------SKDSTPDEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHR 225
Query: 611 AVFRFIPRHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDL 670
+FRF+PRH DE EL+VDDP+LVE + +D+W+ +NMRTG RG F A+YA V + +
Sbjct: 226 TIFRFVPRHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGFFTAYYAIEVTKEPEHM 285
Query: 671 LGSKRSPCWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEIS 730
++ WV++F V+FLGSV+VP H+G+ +L AAMQKIAT R+LTVH PP+SC LEIS
Sbjct: 286 AALAKNSDWVDQFRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEIS 345
Query: 731 LRGVKLSLSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVF 787
+RGVK+ + + +CSHFFQ+KNISF G HP+N+ YFGFITKH RFACHVF
Sbjct: 346 VRGVKIGVKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVF 405
Query: 788 VSQESMRPVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824
VS++S + +A+SVGRAF +++++ + Y CPTEDIYLE
Sbjct: 406 VSEDSTKALAESVGRAFQQFHKQFVEYTCPTEDIYLE 442
Score = 34.7 bits (78), Expect = 0.37
Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 86 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGS--EAPAPGPLIPSPSVEEPHKHRPTTLRL 143
+++EEDD++E G + + G +P S + + G S + RPTTL L
Sbjct: 17 EDDEEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNL 76
Query: 144 --TTLGAQDSLNNN 155
+QD+LNNN
Sbjct: 77 FPQVQLSQDTLNNN 90
>gi|169211037 PREDICTED: similar to mitogen-activated protein kinase
8 interacting protein 1 [Homo sapiens]
Length = 423
Score = 335 bits (859), Expect = 1e-91
Identities = 171/330 (51%), Positives = 226/330 (68%), Gaps = 31/330 (9%)
Query: 519 TQLELVSLRRCAGLGHDSEEDSG---------------------GEASEEEAGAALLGGG 557
T LELVSLR C + E DS EAS + A L
Sbjct: 101 TLLELVSLRPCFR-DYSDESDSAIVYDNCASVSSPYESAIGEEYEEASRPQPPACL---- 155
Query: 558 QVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIP 617
S D++PD PD+ FSKKFLN+F++ SRSSS ESFGLFSC++N EE+EQTHR +FRF+P
Sbjct: 156 --SKDSTPDEPDVHFSKKFLNIFMSGRSRSSSAESFGLFSCIINREEQEQTHRTIFRFVP 213
Query: 618 RHPDELELDVDDPVLVEAEEDDFWFRGFNMRTGERGVFPAFYAHAVPGPAKDLLGSKRSP 677
RH DE EL+VDDP+LVE + +D+W+ +NMRTG RG+F A+YA V + + ++
Sbjct: 214 RHEDEPELEVDDPLLVELQAEDYWYEAYNMRTGARGIFTAYYAIEVTKEPEHMAALAKNS 273
Query: 678 CWVERFDVQFLGSVEVPCHQGNGILCAAMQKIATARKLTVHLRPPASCDLEISLRGVKLS 737
WV++F V+FLGSV+VP H+G+ +L AAMQKIAT R+LTVH PP+SC LEIS+RGVK+
Sbjct: 274 DWVDQFRVKFLGSVQVPYHKGDVVLSAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIG 333
Query: 738 LSGGGPE---FQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMR 794
+ + +CSHFFQ+KNISF G HP+N+ YFGFITKH RFACHVFVS++S +
Sbjct: 334 IKADDSQEAKGNKCSHFFQLKNISFRGYHPKNNKYFGFITKHLADHRFACHVFVSEDSTK 393
Query: 795 PVAQSVGRAFLEYYQEHLAYACPTEDIYLE 824
+A+SVGRAF +++++ + Y CPTE+IYLE
Sbjct: 394 ALAESVGRAFQQFHKQFVEYTCPTENIYLE 423
Score = 32.7 bits (73), Expect = 1.4
Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 4/71 (5%)
Query: 89 EEDDEDEEEEEEEEEGDGEGQEGGDPGS--EAPAPGPLIPSPSVEEPHKHRPTTLRL--T 144
EEDD++E G + + G +P S + + G S + RPTTL L
Sbjct: 17 EEDDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQ 76
Query: 145 TLGAQDSLNNN 155
+QD+LNNN
Sbjct: 77 VQLSQDTLNNN 87
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 64.3 bits (155), Expect = 4e-10
Identities = 128/500 (25%), Positives = 182/500 (36%), Gaps = 104/500 (20%)
Query: 70 PICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPS 129
P + +++ +E E ++ EEED+E+EEEEEEEEE + E +E + + A A G ++ S
Sbjct: 727 PQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRS 786
Query: 130 VEEPHKHRPTTLRL-----TTLGAQDSLNNNGGFDL----VRPASWQET-ALCSPAPEAL 179
+T R +TL A D + G + + P +T L SP
Sbjct: 787 GSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKK 846
Query: 180 RELPGPL-PATDTGPGGAQSP--VRP---GCDCEGNRPA----------EPPAP------ 217
+ L P D G A +P RP G + + P +PP P
Sbjct: 847 SPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGA 906
Query: 218 -------GGTSPSSDPGIEAD-----------LRSRSSGGR--------GGRRSSQELSS 251
GG + +S P + + L SSGG+ G EL+S
Sbjct: 907 GTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELAS 966
Query: 252 PGSDSEDAGGARL--GRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEP 309
G E+ A L G +S ++ E+E S+ G+ S TNS+ + A P P
Sbjct: 967 DGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPSEMATNSLPNGPALADGPAP 1026
Query: 310 --PREP---------PRRPAF--------LPV--GPDDTNSEYESGSESEPDLSEDADSP 348
P EP PRR A +PV +DT SE ++ S+ A
Sbjct: 1027 VSPLEPSPEKVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQ 1086
Query: 349 WLLSNLVSRMISEGSSPIRCPGQCLSPA---PRPPGEPVSPAGGAAQDSQDPEAAAGPGG 405
L+ LV +G +R S + R E +S G AAA P
Sbjct: 1087 QDLARLVMEK-RQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRK 1145
Query: 406 VELVDMETLCAPPPPAPAAPRPGPA-QPGPCLFLSNPTRDTI--------TPLWAA---- 452
P P P P A QP + P DT TP +A
Sbjct: 1146 SGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATAAD 1205
Query: 453 ------PGRAARPGRACSAA 466
PGR PGRA + A
Sbjct: 1206 LRPKQPPGRGLGPGRAQAGA 1225
Score = 32.3 bits (72), Expect = 1.8
Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 7/107 (6%)
Query: 469 EEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRR 528
EEE+EE++EEEE+ E+ A + G PR S + + T E L++ +
Sbjct: 755 EEEEEEEEEEEEEEEEEAAAAVALGE-VLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQ 813
Query: 529 CAGLGHDSEEDSGGEASEEEAGAALLGGGQ-----VSGDTSPDSPDL 570
G S D E E L+ G V+ + +PD PDL
Sbjct: 814 KESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPD-PDL 859
Score = 31.2 bits (69), Expect = 4.1
Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 28/167 (16%)
Query: 174 PAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLR 233
P P LR P+P P P D + P G++ + ADLR
Sbjct: 1157 PRPIGLRM---PMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGSATA------ADLR 1207
Query: 234 SRSSGGRG-GRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSH 292
+ GRG G +Q + P + R R+ +S S +S+S RS
Sbjct: 1208 PKQPPGRGLGPGRAQAGARPPAP-------RSPRLPASTSAAR-------NASASPRSQS 1253
Query: 293 LTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEP 339
L+ E+ SP+ + P PPR PD T S GS+ P
Sbjct: 1254 LSR--RESPSPSHQARPGVPPPRGVPPARAQPDGTPS--PGGSKKGP 1296
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 59.7 bits (143), Expect = 1e-08
Identities = 86/428 (20%), Positives = 159/428 (37%), Gaps = 68/428 (15%)
Query: 88 EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 147
EEE + EEE +EEE G+ E EGG+ +++P P+ P K +
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSP------PAEEAASPEKEAKSP------- 519
Query: 148 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCE 207
V+ + SP E + PA P A+SP + E
Sbjct: 520 -------------VKEEAKSPAEAKSPEKEEAKS-----PAEVKSPEKAKSPAKE----E 557
Query: 208 GNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPG-SDSEDAGGARLGR 266
P E +P S +++ +++S + +E SP + S + + +
Sbjct: 558 AKSPPEAKSPEKEEAKSPAEVKSPEKAKSP-------AKEEAKSPAEAKSPEKAKSPVKE 610
Query: 267 MISSISETELELSSDGGSSSSGRSSHLTNS--IEEASSPASEPEPPREPPRRPAFLPVGP 324
S +E + + + S + +S S EEA SP P +E + P
Sbjct: 611 EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSP---EKAK 667
Query: 325 DDTNSEYESGSESEPDLSEDADSPWLLSNLV---SRMISEGSSPI----RCPGQCLSPAP 377
+E +S +++ + +A SP + V ++ + SP+ + P + SP
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Query: 378 RPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLF 437
P ++++ PE A P + +D+++ A P A P P
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKA-- 785
Query: 438 LSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD------EEEEDAEDSAGSPGG 491
+P ++ + +P +A P + + A +E ++++ EEE+ E P
Sbjct: 786 -KSPVKEEV----KSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPK 840
Query: 492 RGTGPSAP 499
+ AP
Sbjct: 841 KAEEEKAP 848
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 58.9 bits (141), Expect = 2e-08
Identities = 90/342 (26%), Positives = 119/342 (34%), Gaps = 55/342 (16%)
Query: 134 HKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGP 193
H H P L L + + DS + GG SP P P P P GP
Sbjct: 218 HLHSPGGLSLHSAPSSDSDSGGGGL--------------SPEP------PEPPPPAAKGP 257
Query: 194 GGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG---RGGRRSSQELS 250
G S P EPPAPG P+ P RS G R GR + ++ +
Sbjct: 258 GAHASGAAGTAPAP---PGEPPAPGTCDPAFYPS------QRSGAGPQPRPGRPADKDAA 308
Query: 251 SPGSDSEDAGGARLGRMISSISETELE-LSSDGGSSSSGRSSHLTNSIEEASSPASEPEP 309
S G + A R + S +E L SD S+ + P
Sbjct: 309 SCGPGAAVAAVERGAAGLPKASPFSVESLLSDSPPRRKAASNAAAAAAAGLDFAPGLPCA 368
Query: 310 PREPPRRPAFL------PVGPDDTNSEYESGSESEPDLSEDADSPWL-----LSNLVSRM 358
PR + FL P+G + + G+ EP + +P +
Sbjct: 369 PRTLIGKGHFLLYPITQPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPPAPPAQASFGAF 428
Query: 359 ISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETL-CAP 417
G +P + A PG P +PA +D A G GG + D T AP
Sbjct: 429 SGPGGAPDSAFARRSPDAVASPGAP-APAPAPFRDLASAAATEGGGG-DCADAGTAGPAP 486
Query: 418 PPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARP 459
PPPAP +PRPGP P +P + T PG AA P
Sbjct: 487 PPPAP-SPRPGPRPP-------SPAEEPATCGVPEPGAAAGP 520
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 57.8 bits (138), Expect = 4e-08
Identities = 100/385 (25%), Positives = 133/385 (34%), Gaps = 87/385 (22%)
Query: 124 LIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELP 183
L PSP P L+ +LG ++ D + +S+ AL + A +P
Sbjct: 588 LAPSPRCPPP---LACALQAFSLGQRE--------DSLEVSSFCSEALVTCAALTHPRVP 636
Query: 184 GPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGR 243
P T P A P P E P+P P PG + S S G
Sbjct: 637 PLQPMGPTCPTPAPVP-----------PPEAPSPFRAPPFHPPGPMPSVGSMPSAG---- 681
Query: 244 RSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSS-----GRSSHLTNSIE 298
+ S G AG R + L LS G S G +H S E
Sbjct: 682 ----PMPSAGP-MPSAGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNE 736
Query: 299 EASSPASEPEPPREPPR--------RPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWL 350
+ S PP PP RPAF+ + + E S+ E L D+D +
Sbjct: 737 DPILAPSGTPPPTIPPDETFGGRVPRPAFV-------HYDKEEASDVEISLESDSDDSVV 789
Query: 351 LSNLVSRMISEGSSPIRCP--GQCLSPAPRPPGEPV-SPAGGAAQDSQDPEAAAGPGGVE 407
+ + EG P+ P P P G P SP A ++ ++ AA GP
Sbjct: 790 I-------VPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGP---- 838
Query: 408 LVDMETLCAPPPPAPAAPRPGPAQ-PGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAA 466
PPPP P P PGP P P L TP P +
Sbjct: 839 --------LPPPPPPPPPVPGPVTLPPPQLVPEG------TPGGGGPPALEEDLTVININ 884
Query: 467 CS-------EEEDEEDDEEEEDAED 484
S EEE+EE++EEEE+ ED
Sbjct: 885 SSDEEEEEEEEEEEEEEEEEEEEED 909
Score = 48.5 bits (114), Expect = 2e-05
Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 13/134 (9%)
Query: 17 SPPGCRPP---QDISL-------EEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSE 66
+P G PP +D+++ EE ++E+ E ++ D + E+D E
Sbjct: 865 TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEE 924
Query: 67 QPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGE-GQEGGDPGSEAPAPGPLI 125
+ F+++F+E E + EEE++++EEEEE EE D E G GG+ AP P L
Sbjct: 925 EEEEE-EFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLP 983
Query: 126 PS-PSVEEPHKHRP 138
P+ P E P K +P
Sbjct: 984 PALPPPESPPKVQP 997
>gi|151101459 SAPS domain family, member 1 [Homo sapiens]
Length = 881
Score = 57.0 bits (136), Expect = 7e-08
Identities = 72/240 (30%), Positives = 98/240 (40%), Gaps = 28/240 (11%)
Query: 29 LEEFDDEDLSEITDDC-GLGLSYDSDHCEKDS-LSLG-RSEQPHPICSFQDDFQEFEMID 85
+++FDD++ E ++ G G S D + S L+ G R QP + S
Sbjct: 617 IQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGST-------- 668
Query: 86 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTT 145
D+E+E++EDEEEE E+EEG G GG P+PGP P PS PT
Sbjct: 669 DSEDEEEEDEEEE-EDEEGIGCAARGGATPLSYPSPGPQPPGPSWTATFDPVPT------ 721
Query: 146 LGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCD 205
A S +G +L + L P + L P PA D +Q P P
Sbjct: 722 -DAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASP-PARDALQLRSQDPTPPSAP 779
Query: 206 ---CEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGA 262
EG++ EP AP S DL++ G R SS + S S A GA
Sbjct: 780 QEATEGSKVTEPSAPCQALVSI-----GDLQATFHGIRSAPSSSDSATRDPSTSVPASGA 834
Score = 46.6 bits (109), Expect = 9e-05
Identities = 74/314 (23%), Positives = 110/314 (35%), Gaps = 50/314 (15%)
Query: 85 DDNEEEDDEDEEEEEEEEEGDGE--GQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLR 142
D ++ DD++EEE+EEE +G GE G++G GS+ L P V T
Sbjct: 615 DRIQQFDDDEEEEDEEEAQGSGESDGEDGAWQGSQLARGARLGQPPGVRSGGS---TDSE 671
Query: 143 LTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRP 202
++ + G + SP P+ PGP P +P P
Sbjct: 672 DEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQP----PGPSWTATFDPVPTDAPTSP 727
Query: 203 GCDCEGNRPAEPPAPGGTSPSSDP-GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGG 261
E PPAP G P S P G+ + + SQ+ + P + E G
Sbjct: 728 RVSGEEELHTGPPAPQG--PLSVPQGLPTQSLASPPARDALQLRSQDPTPPSAPQEATEG 785
Query: 262 ARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLP 321
++ ++ S L S G ++ S+P+S R+P
Sbjct: 786 SK----VTEPSAPCQALVSIGDLQATFHGIR--------SAPSSSDSATRDP-------- 825
Query: 322 VGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPG 381
+ S SG+ P +E SP L P Q L+P P P G
Sbjct: 826 -----STSVPASGAHQPPQTTEGEKSPEPL-----------GLPQSQSAQALTPPPIPNG 869
Query: 382 EPVSPAGGAAQDSQ 395
+P G A+ SQ
Sbjct: 870 S--APEGPASPGSQ 881
Score = 33.9 bits (76), Expect = 0.63
Identities = 56/235 (23%), Positives = 84/235 (35%), Gaps = 17/235 (7%)
Query: 208 GNRPAEPPA--PGGTSPSSDPGIEADLRSRSSGGRG--GRRSSQELSSPGSDSEDAGGAR 263
G R +PP GG++ S D E + G G R + LS P + G +
Sbjct: 653 GARLGQPPGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPSW 712
Query: 264 LGRM--ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP-REPPRRPAFL 320
+ + + T +S + + + S+ + S PP R+ + +
Sbjct: 713 TATFDPVPTDAPTSPRVSGEEELHTGPPAPQGPLSVPQGLPTQSLASPPARDALQLRSQD 772
Query: 321 PVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPP 380
P P E +EP S + + +L + S+P A R P
Sbjct: 773 PTPPSAPQEATEGSKVTEP--SAPCQALVSIGDLQATFHGIRSAP-----SSSDSATRDP 825
Query: 381 GEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA-PPPPAPAAPRP-GPAQPG 433
V PA GA Q Q E P + L ++ A PPP P P GPA PG
Sbjct: 826 STSV-PASGAHQPPQTTEGEKSPEPLGLPQSQSAQALTPPPIPNGSAPEGPASPG 879
Score = 33.1 bits (74), Expect = 1.1
Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 13/52 (25%)
Query: 459 PG-RACSAACSEEEDEEDDEEEEDAED------------SAGSPGGRGTGPS 497
PG R+ + SE+E+EED+EEEED E S SPG + GPS
Sbjct: 660 PGVRSGGSTDSEDEEEEDEEEEEDEEGIGCAARGGATPLSYPSPGPQPPGPS 711
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 55.8 bits (133), Expect = 2e-07
Identities = 95/407 (23%), Positives = 137/407 (33%), Gaps = 63/407 (15%)
Query: 75 QDDFQEFEMIDDNEEEDDEDEEE------------EEEEEEGDGEGQEGGDP----GSEA 118
+D+ E + NEEE E+ E E GQ G P G++
Sbjct: 701 EDEEMEASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADG 760
Query: 119 PAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPA-----SWQETALCS 173
P PGP P P + P PT T GA P +ETA
Sbjct: 761 PPPGPPTPPPE-DIPAPTEPTPASEAT-GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAP 818
Query: 174 PAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLR 233
P E + P G A+ PV+ C E E PA G + +++ E L+
Sbjct: 819 PVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAE---EGPAKGKDAEAAEATAEGALK 875
Query: 234 SRSSGGRGGRRSSQELSSPGSDS-----------EDAGGARLGRMISSISETELELSSDG 282
+ G GR ++ + S DS ++A G R++S
Sbjct: 876 AEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPR 935
Query: 283 GSSSSGRSSHLTNSIEEASS-----PASEPEPPRE--PPRRPAFLPVGPDDTNSEYESGS 335
++S + L + A++ EPPRE P +PA P P N + ES +
Sbjct: 936 ANASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPA-PPAPPPPQNLQPESDA 994
Query: 336 ESEPDLS-------------EDADSPWLLSNLVSRMIS-EGSSPIRCPGQCLSPAPRPPG 381
+P S ++A+ P + G P G P P PP
Sbjct: 995 PQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSG---LPFPVPPR 1051
Query: 382 EPVSPAGGAAQDSQDPEAAAG-PGGVELVDMETLCAPPPPAPAAPRP 427
E + + A S A G P + L D P PP + P P
Sbjct: 1052 EVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNPPP 1098
Score = 40.0 bits (92), Expect = 0.009
Identities = 59/272 (21%), Positives = 93/272 (34%), Gaps = 38/272 (13%)
Query: 292 HLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDD-------TNSEYESGSESEPDLSED 344
H +E ++ + + P AF PV D+ + +E E E+E ++
Sbjct: 669 HKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEATVNNS 728
Query: 345 ADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPG 404
+D+ + S G + + P + P PPG P P PE P
Sbjct: 729 SDTESIPSPHTEAAKDTGQNGPKPPATLGADGP-PPGPPTPP----------PEDIPAPT 777
Query: 405 GVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACS 464
T PPPAP P P+ P P + +T G +P A
Sbjct: 778 EPTPASEATGAPTPPPAP----PSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEE 833
Query: 465 AACSEEEDEEDDEEE--EDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVD-EHTQL 521
A + EE + E E+AE+ GP+ +DA + L + +
Sbjct: 834 LAVDTGKAEEPVKSECTEEAEE----------GPAKGKDAEAAEATAEGALKAEKKEGGS 883
Query: 522 ELVSLRRCAGLGHDSEED---SGGEASEEEAG 550
+ + +G DS+ S E E E G
Sbjct: 884 GRATTAKSSGAPQDSDSSATCSADEVDEAEGG 915
Score = 31.2 bits (69), Expect = 4.1
Identities = 65/274 (23%), Positives = 89/274 (32%), Gaps = 62/274 (22%)
Query: 86 DNEEEDDEDEEEEEE------------------EEEGDGEGQEGGDPGSEA-PAP----- 121
D + E D D E E+ E+ G GG GS + PA
Sbjct: 1790 DRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAH 1849
Query: 122 --GPLIPSPSVEEPHKHRPTTLRLTTL---------GAQDSLNNNGGFDLVRPASWQETA 170
P+ SP ++ + RP+ L T + L + VRPA+ A
Sbjct: 1850 QHSPI--SPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPA 1907
Query: 171 LCSPAPEALR----ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 226
P L L P+ P A+ P RP D A+PPA G P+S P
Sbjct: 1908 THCPLGGTLDGVYPTLMEPVLLPKEAPRVAR-PERPRADTGHAFLAKPPARSGLEPASSP 1966
Query: 227 --GIE-----------ADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISE 273
G E A + + +S + +P + + D + SI E
Sbjct: 1967 SKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQE 2026
Query: 274 TELELSSDGGSSSSGRSSHLTNSIEEASSPASEP 307
EL GSS S E SP S P
Sbjct: 2027 LELRSLGYHGSSYSPEG-------VEPVSPVSSP 2053
Score = 30.4 bits (67), Expect = 7.0
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 35/135 (25%)
Query: 400 AAGPGGV-ELVDMETLCAPPPPAPAAPRPG-------PAQPGPCLFLSNPTRDTITPLWA 451
AAGP G+ +L + L PP P P P P P F S + ++P
Sbjct: 1716 AAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQP--FSSRHSSSPLSP--G 1771
Query: 452 APGRAARPGRACSAACSEEEDEEDDEEEE-----------------------DAEDSAGS 488
P +P S+ + D E D + E + S+GS
Sbjct: 1772 GPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGS 1831
Query: 489 PGGRGTGPSAPRDAS 503
GG G S P S
Sbjct: 1832 SGGGGGSSSRPASHS 1846
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 55.8 bits (133), Expect = 2e-07
Identities = 74/287 (25%), Positives = 97/287 (33%), Gaps = 62/287 (21%)
Query: 166 WQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGT----- 220
WQE P++L L PA G+ P P A+ P PG T
Sbjct: 2492 WQE-------PKSLLSLGSYPPAA-----GSSEPKAPWPKATDGDLAQEPGPGLTFEDSG 2539
Query: 221 SPSSDPGIEADL------RSRSSGGRGGRRSSQELSSPGSDSE---------DAGGARLG 265
+P S +A+ S SS G SS SS GS++E D G G
Sbjct: 2540 NPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGG 2599
Query: 266 RMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPD 325
R S+ S +S SSSS SS ++S +SS +S
Sbjct: 2600 RNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSS------------------- 2640
Query: 326 DTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVS 385
++S S S S S + S S+ S E SS +P P +
Sbjct: 2641 -SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAAL 2699
Query: 386 PAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQP 432
P Q + +A PG P P P AP P P QP
Sbjct: 2700 PTKATKQAGKARPSAHSPGK----------KTPAPQPQAPPPQPTQP 2736
Score = 53.1 bits (126), Expect = 1e-06
Identities = 96/396 (24%), Positives = 136/396 (34%), Gaps = 84/396 (21%)
Query: 106 GEGQEGGDPGSEAP--------------APGPLIPSPSVEEPHKHRPTT-LRL---TTLG 147
GEG++GG GSE P A G + P P+T L L +T G
Sbjct: 2312 GEGKDGGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSSTPG 2371
Query: 148 AQDS----LNNNGGFDLVRPASWQETA-----LCSPAPEALRELPGP-----------LP 187
++ S ++ RPA Q + PAPE ELP P +P
Sbjct: 2372 SKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMP 2431
Query: 188 ATDTGP--------GGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG 239
AT P GA+ P RPG + E + G TSP S EA L R G
Sbjct: 2432 ATRPKPKKARAAEESGAKGPRRPGEEAE--LLVKLDHEGVTSPKSKKAKEA-LLLREDPG 2488
Query: 240 RGGRRSSQELSSPGSDSEDAGGARLGRMISSISETEL----------------------E 277
GG + + L S GS AG + ++ +L +
Sbjct: 2489 AGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQ 2548
Query: 278 LSSDG---GSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESG 334
DG SSS SS ++S +SS SE E E G + + +G
Sbjct: 2549 AEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEE----------GDKNGDGGCGTG 2598
Query: 335 SESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDS 394
+ S A SP S+ S S SS S + S + ++ S
Sbjct: 2599 GRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2658
Query: 395 QDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPA 430
+++ D ++ C+ A AP GP+
Sbjct: 2659 SSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPS 2694
Score = 48.9 bits (115), Expect = 2e-05
Identities = 72/277 (25%), Positives = 101/277 (36%), Gaps = 50/277 (18%)
Query: 73 SFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGG-----DPGSEAPAPGPL--- 124
SF D +E D++ EE+DE+EE EEE+E G + G PG E G L
Sbjct: 1812 SFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGYRLGARERALSPGLEESGLGLLARF 1871
Query: 125 ----IPSPSV---------EEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPAS-----W 166
+PSP+V E K R R + LG + ++ VR S
Sbjct: 1872 AASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLR 1931
Query: 167 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNR-PAEPPAPGGTSPSSD 225
+ L P P PG + P A+ V G R P EP G S D
Sbjct: 1932 PKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDD 1991
Query: 226 PGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSS 285
DL +R RRS + S + A +S+ T+ + GG
Sbjct: 1992 -----DLWTR-------RRSERIFLHDASAAAPA-------PVSTAPATKTSRCAKGGPL 2032
Query: 286 S----SGRSSHLTNSIEEASSPASEPEPPREPPRRPA 318
S +GR+ + ++ + P PPR PA
Sbjct: 2033 SPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPA 2069
Score = 45.1 bits (105), Expect = 3e-04
Identities = 93/414 (22%), Positives = 150/414 (36%), Gaps = 74/414 (17%)
Query: 218 GGTSPSSDPGIEADLRSR--SSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETE 275
GGT+ S +PG +A R R S+ +G R ++ E +P + + T
Sbjct: 2317 GGTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDE---------------VPSTP 2361
Query: 276 LELSSDGGSSSSGRSSHLTNSIEE-ASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESG 334
L L SS+ G +++ A +P + P PP+ P PAF + +E +
Sbjct: 2362 LALEP---SSTPGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAP 2418
Query: 335 SES---EPDLSEDADSPWLLSNLVSRMISE-GSSPIRCPGQCLSPAPRPPGEPV-SPAGG 389
+ S P ++ A P +R E G+ R PG+ + E V SP
Sbjct: 2419 ATSLAPAPLITMPATRP---KPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSK 2475
Query: 390 AAQDS----QDPEAAAGPGGVELVDMETLCAPPPPA----PAAPRPGPA------QPGPC 435
A+++ +DP A G E + +L + PP A P AP P +PGP
Sbjct: 2476 KAKEALLLREDPGAG---GWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPG 2532
Query: 436 LFL------SNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSP 489
L +P + A ++ + S++ S E E + E
Sbjct: 2533 LTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGD 2592
Query: 490 GGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEA 549
GG GTG R+ S S R + S S +S +
Sbjct: 2593 GGCGTG---GRNCS-------------------AASSRAASPASSSSSSSSSSSSSSSSS 2630
Query: 550 GAALLGGGQVSGDTSPDSPDLTFSKKFLNVFVNSTSRSSSTESFGLFSCLVNGE 603
++ S +S S + S + +S+S SSS+ + SC + E
Sbjct: 2631 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDE 2684
Score = 40.4 bits (93), Expect = 0.007
Identities = 50/207 (24%), Positives = 69/207 (33%), Gaps = 29/207 (14%)
Query: 115 GSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSP 174
G A PGP + P P + GA++S +++ +S ++ S
Sbjct: 2523 GDLAQEPGPGLTFEDSGNPKS--PDKAQAEQDGAEESESSSS-------SSSGSSSSSSS 2573
Query: 175 APEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRS 234
+ + E G G GG + R C +R A P + +S SS + S
Sbjct: 2574 SSSSGSETEGEEEGDKNGDGGCGTGGR-NCSAASSRAASPASSSSSSSSSSSSSSSSSSS 2632
Query: 235 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 294
SS SS SS S S + SS SSSS SS T
Sbjct: 2633 SSSSSSSSSSSSSSSSSSSSSSSSS-------------------SSSSSSSSSSSSSSTT 2673
Query: 295 NSIEEASSPASEPEPPREPPRRPAFLP 321
+ SS P P A LP
Sbjct: 2674 DEDSSCSSDDEAAPAPTAGPSAQAALP 2700
Score = 38.1 bits (87), Expect = 0.034
Identities = 105/468 (22%), Positives = 157/468 (33%), Gaps = 108/468 (23%)
Query: 57 KDSLSLGRSEQPHPICSFQDDF----QEFE----MIDDNEEEDDEDEEEEEEEEEGDGEG 108
K L+ R+ +P P S + F +E E D +EE D+DE EEE+EE + E
Sbjct: 1779 KRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEESFDQDESSEEEDEEEELEE 1838
Query: 109 QEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQE 168
++ EA G LGA++ + G +E
Sbjct: 1839 ED------EASGGG---------------------YRLGARERALSPG---------LEE 1862
Query: 169 TALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTS-PSSDPG 227
+ L A A LP P G + S V+ + + E + GT +D
Sbjct: 1863 SGLGLLARFAASALPSPTV------GPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSE 1916
Query: 228 IEADLRSRSSGGRGGRRSSQELSSPG-SDSEDAGGARLGRMISSISETELELSSDGGSSS 286
E +R RS G R + L PG S + GAR G S
Sbjct: 1917 SEVKVRKRSPAGL--LRPKKGLGEPGPSLAAPTPGAR------------------GPDPS 1956
Query: 287 SGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDAD 346
S + L E A + P+EP GP+ ++ + + SE DA
Sbjct: 1957 SPDKAKLA---VEKGRKARKLRGPKEPG-----FEAGPEASDDDLWTRRRSERIFLHDAS 2008
Query: 347 SPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAA-----A 401
+ + ++P +C P P + G A+D +DP A
Sbjct: 2009 A--------AAPAPVSTAPATKTSRCAKGGPLSPRKDA----GRAKDRKDPRKKKKGKEA 2056
Query: 402 GPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGR 461
GPG PPP APA P A L + ++ + G
Sbjct: 2057 GPGAG---------LPPPRAPALPSEARAPHASSLTAAKRSKAKAKGKEVKKENRGKGGA 2107
Query: 462 ACSA--ACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYD 507
+ + EED E +++ +ED GG P P S + D
Sbjct: 2108 VSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIID 2155
Score = 33.9 bits (76), Expect = 0.63
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 21/123 (17%)
Query: 375 PAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPP--PAPAAPRPGPAQP 432
PA P ++P+ + +++ +AA GP + L AP P PA R P
Sbjct: 1747 PAQGPSSSKLTPSLLCSMVAKNSKAAGGPK----LTKRGLAAPRTLKPKPATSRKQPF-- 1800
Query: 433 GPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGR 492
CL L A R++ + + +E EE+DEEEE E+ S GG
Sbjct: 1801 --CLLLRE-----------AEARSSFSDSSEESFDQDESSEEEDEEEELEEEDEASGGGY 1847
Query: 493 GTG 495
G
Sbjct: 1848 RLG 1850
Score = 30.0 bits (66), Expect = 9.1
Identities = 65/284 (22%), Positives = 93/284 (32%), Gaps = 49/284 (17%)
Query: 192 GPGGAQSPVRPGCDCEGNRPAEPPA---PGGTSPSSDPGIEADLRSRSSGGRGGRRSSQE 248
GPGG P G+ + P+ PGG S P + R + R GR
Sbjct: 159 GPGG-DGFYLPTAGAPGSLHSHAPSARTPGGGHSSGAPAKGSSSRDGPAKERAGRGGEPP 217
Query: 249 ----LSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPA 304
P + E+A G R ++ E E D G + L+ + E+ +
Sbjct: 218 PLFGKKDPRARGEEASGPR--GVVDLTQEARAEGRQDRGPPRL--AERLSPFLAESKTKN 273
Query: 305 SEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSS 364
+ +P VG +E G E ++ +R++ +
Sbjct: 274 AALQPSVLTMCNGGAGDVGLPALVAEAGRGGAKEAARQDEG----------ARLLRRTET 323
Query: 365 PIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDME-----TLCAP-- 417
+ P C SP P PP P P AA P GV V E + AP
Sbjct: 324 LLPGPRPCPSPLPPPPAPPKGPPA---------PPAATPAGVYTVFREQGREHRVVAPTF 374
Query: 418 -PPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPG 460
P RPGP Q +++ RD A A RPG
Sbjct: 375 VPSVEAFDERPGPIQ------IASQARDA----RAREREAGRPG 408
>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
Length = 1489
Score = 55.8 bits (133), Expect = 2e-07
Identities = 70/245 (28%), Positives = 89/245 (36%), Gaps = 48/245 (19%)
Query: 92 DEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDS 151
+E+EEEEE G+ GG P P P PL R L D+
Sbjct: 668 EEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLC----------SREGACSCLPLERGDA 717
Query: 152 LNNNGGFD-LVRPASWQETALCSPAPEALRELPGPLPATDTGP-----GGAQSPVRPGCD 205
+ GG L P ++ + +L +LP PA+ GA +P PG
Sbjct: 718 VAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPG-- 775
Query: 206 CEGNRPAEPPAPGGTSPSSDPGIEADLRSR-SSGGRGGRRSSQELSSPGSDSEDAGGARL 264
G PA PP P +DP D S +S G G LSSPG D+G
Sbjct: 776 -RGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSG-------LSSPGPKPGDSG---- 823
Query: 265 GRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP----REPPRRPAFL 320
ETE S +G G + E P + PEPP PP P L
Sbjct: 824 -------YETETPFSPEGAFPGGGAAEE-----EGVPRPRAPPEPPDPGAPRPPPDPGPL 871
Query: 321 PV-GP 324
P+ GP
Sbjct: 872 PLPGP 876
Score = 47.4 bits (111), Expect = 6e-05
Identities = 130/562 (23%), Positives = 182/562 (32%), Gaps = 138/562 (24%)
Query: 97 EEEEEEEGDGEGQEGGDPGSEAPAPGP--------------LIPSPSVEEPHKHRPTTLR 142
E+ G G G P S PAP ++P S P +R
Sbjct: 511 EKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIR 570
Query: 143 LTTLGAQDSLNNNGGFDLVRPASWQETALCSPA--PEALREL--------PGPLPATDTG 192
L G+ +D + P A +P+ P+ + E P P PA +
Sbjct: 571 LEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSA 630
Query: 193 PGGAQSPVRPGCDCEGNRPAEP----PAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQE 248
G S + G D EG E PA + P +E + +E
Sbjct: 631 SG---SFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEE------------EEEEE 675
Query: 249 LSSPGSDSEDAGG--ARLGRMISSISETELELSS---DGGSSSSGRSSHLTNSIEEASSP 303
SSPG DS GG +R G + + E S + G + +G H P
Sbjct: 676 GSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGH----------P 725
Query: 304 ASE-PEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSP-WLLSNLVSRMISE 361
A P PP DD++ E GS ++ ++ A +P L L+
Sbjct: 726 ALGCPHPPE-------------DDSSLRAERGSLADLPMAPPASAPPEFLDPLM------ 766
Query: 362 GSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPA 421
G++ + PG+ PAP PP P P A A P PP A
Sbjct: 767 GAAAPQYPGRGPPPAPPPPPPP-------------PRAPADPAA---------SPDPPSA 804
Query: 422 PAAPRPGPAQPGPCLFLSN-PTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEE 480
A+P G + PGP S T +P A PG A EE E
Sbjct: 805 VASPGSGLSSPGPKPGDSGYETETPFSPEGAFPG---------GGAAEEEGVPRPRAPPE 855
Query: 481 DAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDS 540
+ A P P P L K T VV T+ L+SLR D +
Sbjct: 856 PPDPGAPRP------PPDPGPLPLPGPREKPTFVVQVSTEQLLMSLR------EDVTRNL 903
Query: 541 GGE--ASEEEAGAALLGGGQVSGDTSP-------------DSPDLTFSKKFLNVFVNSTS 585
GE A+ E G G G + + P +P L+ + V N
Sbjct: 904 LGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQ 963
Query: 586 RSSSTESFGLFSCLVNGEEREQ 607
R+ E + + ERE+
Sbjct: 964 RAPGIEEKAAENGALGSPEREE 985
Score = 47.0 bits (110), Expect = 7e-05
Identities = 84/379 (22%), Positives = 126/379 (33%), Gaps = 94/379 (24%)
Query: 143 LTTLGAQDSLNNNGGFDLVR-------------PASWQET--------ALCSPAPE-ALR 180
LT ++D ++ NGG R P W++T + PAPE +L
Sbjct: 1023 LTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLE 1082
Query: 181 ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGR 240
P P + GG +P P P + + +PG E R+ +GG
Sbjct: 1083 RAPAPSAVVSSRNGGETAP-------------GPLGPAPKNGTLEPGTER--RAPETGGA 1127
Query: 241 GGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHL--TNSIE 298
+PG+ D G GR ++ GG SG + ++
Sbjct: 1128 P--------RAPGAGRLDLGSG--GRAPVGTG------TAPGGGPGSGVDAKAGWVDNTR 1171
Query: 299 EASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRM 358
P P PP PRR + P + E E EP +
Sbjct: 1172 PQPPPPPLPPPPEAQPRR-----LEPAPPRARPEVAPEGEPGAPDSR------------- 1213
Query: 359 ISEGSSPIRCPGQCLSPAPRPPGEP--VSPAGGAAQDSQDPEAAAGPGGVELVDMETLCA 416
+ G + + G P + P P G +S+ +A + +L
Sbjct: 1214 -AGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKAR--------LSRLSLAL 1264
Query: 417 PPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDD 476
PP P PGP +P P AA G A G A E+++ED+
Sbjct: 1265 PPLTLTPFPGPGPRRP--------PWEGA--DAGAAGGEAGGAGAPGPAEEDGEDEDEDE 1314
Query: 477 EEEEDAEDSAGSPGGRGTG 495
EE+E+A + G RG G
Sbjct: 1315 EEDEEAAAPGAAAGPRGPG 1333
Score = 36.6 bits (83), Expect = 0.097
Identities = 38/149 (25%), Positives = 57/149 (38%), Gaps = 22/149 (14%)
Query: 85 DDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLT 144
+D E+ED+++EE+EE G G G PG AP P++ S + + RP L
Sbjct: 1305 EDGEDEDEDEEEDEEAAAPGAAAGPRG--PGRARAAPVPVVVSSA--DADAARPLRGLLK 1360
Query: 145 TLGAQDSLNNNGGFDLVRPASWQETALC------SPAPEALRELPGPLPATDTGPGGAQS 198
+ D ++ + S+ +P E + P P DT P +
Sbjct: 1361 SPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAP---PEGDTDPSTPPA 1417
Query: 199 PVRPGCDCEGNRPAEPPAPGGTSPSSDPG 227
P P P PG PS+D G
Sbjct: 1418 P---------PTPPHPATPGDGFPSNDSG 1437
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 55.5 bits (132), Expect = 2e-07
Identities = 100/394 (25%), Positives = 127/394 (32%), Gaps = 73/394 (18%)
Query: 118 APAPGPLIPSP--SVEEPHKHRPTTLRLTTLGAQDSLNNN---------GGFDLVRPASW 166
A APG L P P S P P LR+ LGA ++ GG + A
Sbjct: 19 ARAPGLLTPRPPGSPRPPPPVTPAALRV--LGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 167 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 226
S P + R P PA +T PG SP R G P G S++
Sbjct: 77 AGPTRTSRPPASGRGERAP-PAKNTSPGPVSSPGR----ASGTTRPGPLGQKGLRISAEE 131
Query: 227 ----GIEADLRSRSSGGRGGRRSSQELSSPGSDS------EDAGGARLG----------- 265
G + RS+ G RR + +PG+ S A G +G
Sbjct: 132 TVARGKATEAPKRSALSAGARRDTSG-PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190
Query: 266 -------RMISSISETEL--------ELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP 310
+ +SS SE S GG S L++S SSPA
Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250
Query: 311 REPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPG 370
R PR PA P P + + P + A + LS SSP+ P
Sbjct: 251 RGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGPLS----------SSPLATPS 299
Query: 371 QCLSPAPRPP-------GEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPA 423
P+P P P +P A P A + + L PPP AP
Sbjct: 300 PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 424 APRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAA 457
A P Q P S P TP AP A
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393
Score = 41.6 bits (96), Expect = 0.003
Identities = 95/367 (25%), Positives = 121/367 (32%), Gaps = 53/367 (14%)
Query: 111 GGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNN--NGGFDLVRPASWQ- 167
G + G PAP P P E P K + +T + + G L RPAS
Sbjct: 175 GTEVGLPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 168 ---ETALCSPA---PEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT 220
T L SPA P A P + P G Q+ +RP + A P P +
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSS 292
Query: 221 SPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSS 280
SP + P A + S Q L SP + LG + + L
Sbjct: 293 SPLATPSPSAPPSPSAPP------SLQTLPSPPATPPSQATTSLGSPTLQATHSFLP--- 343
Query: 281 DGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPD 340
S S L +A PA P + PP PA P+ P T S + +
Sbjct: 344 ------SPPLSPLATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396
Query: 341 LSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEP-VSPAGGAAQDSQDPEA 399
L P S P++ P SP PP P +P A P
Sbjct: 397 LQAPFSPP-------------PSPPVQAP---FSPPASPPVSPSATPPSQAPPSLAAPPL 440
Query: 400 AAGPGGVELVDMETLCAPPPPAP---AAPRPGPAQPGPCLFLSNPTRDTITPLWAAPG-R 455
P M PPP AP AAP A+P P P PL A P
Sbjct: 441 QVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQALPSPP 496
Query: 456 AARPGRA 462
A+ PG+A
Sbjct: 497 ASFPGQA 503
Score = 40.4 bits (93), Expect = 0.007
Identities = 43/134 (32%), Positives = 56/134 (41%), Gaps = 22/134 (16%)
Query: 163 PASWQETALCSPAPE-ALRELPG-PLP-ATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGG 219
PA+W PAP A R PG PLP TGPG A + + EG A P APG
Sbjct: 629 PAAWSR----GPAPPLAFRGAPGAPLPWPPATGPGSADG-LCTIYETEGPESATP-APGA 682
Query: 220 TSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSI-----SET 274
P PG +SGG+ + SS G LG + +S+ S T
Sbjct: 683 LDPGPSPG--------TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRT 734
Query: 275 ELELSSDGGSSSSG 288
L +++G + SG
Sbjct: 735 LLLAAAEGAAGGSG 748
Score = 37.7 bits (86), Expect = 0.044
Identities = 92/390 (23%), Positives = 121/390 (31%), Gaps = 42/390 (10%)
Query: 118 APAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPE 177
APA GPL SP P+ +L S P S T+L SP +
Sbjct: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS-------PPATPPSQATTSLGSPTLQ 336
Query: 178 ALRE-LPGP--LPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT-SPSSDPGIEADL 232
A LP P P P + P + PA PP +P T SP + + L
Sbjct: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 396
Query: 233 RSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSH 292
S P S + S++ L++ +S S
Sbjct: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS- 455
Query: 293 LTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLS 352
A+ P P P PP + A P + + P S +P+
Sbjct: 456 -------ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF--- 505
Query: 353 NLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDME 412
S S SP+ P P P V P+ A+ Q P PG V
Sbjct: 506 ---SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562
Query: 413 TLC---APPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSE 469
L AP PP P + P GP L + + T TP R G AA S
Sbjct: 563 RLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP---EELRGYDSGPEGGAAAS- 617
Query: 470 EEDEEDDEEEEDAEDSAGSPGGRGTGPSAP 499
DAE +A P GP+ P
Sbjct: 618 --------PPPDAELAACHPAAWSRGPAPP 639
Score = 35.8 bits (81), Expect = 0.17
Identities = 48/160 (30%), Positives = 58/160 (36%), Gaps = 37/160 (23%)
Query: 367 RCPGQCLSPAPRPPGEPVSP------------AGGAAQDSQDPEAAAGPGGVELVDMETL 414
R PG PRPPG P P A GA E A G GG + +
Sbjct: 20 RAPGLL---TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 415 CAP-----PPPAPAAPRPGPAQ---PGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAA 466
P PP + R PA+ PGP +S+P R + T PG + G SA
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGP---VSSPGRASGT---TRPGPLGQKGLRISA- 129
Query: 467 CSEEEDEEDDEEEEDAEDSAGSPGGR----GTGPSAPRDA 502
EE + E + SA S G R G P P A
Sbjct: 130 ---EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 166
Score = 33.5 bits (75), Expect = 0.83
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 22/137 (16%)
Query: 304 ASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGS 363
A P PP P R P+ GPD + S + S P+ DS EG
Sbjct: 567 ALAPGPPPPPSRSPSSTLSGPDLAG--HSSSATSTPEELRGYDSG-----------PEGG 613
Query: 364 SPIRCPGQCLSPAPRP------PGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP 417
+ P A P P P++ G P A GPG + + T+
Sbjct: 614 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT-GPGSAD--GLCTIYET 670
Query: 418 PPPAPAAPRPGPAQPGP 434
P A P PG PGP
Sbjct: 671 EGPESATPAPGALDPGP 687
>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
sapiens]
Length = 304
Score = 55.1 bits (131), Expect = 3e-07
Identities = 39/132 (29%), Positives = 69/132 (52%), Gaps = 7/132 (5%)
Query: 683 FDVQFLGSVEVPCHQGNGILCAAMQKIATAR--KLTVHLRPPASCDLEISLRGVKLSLSG 740
++ +FLGS EV +G ++ A++K+ AR K + + P +L+IS+ GVK+
Sbjct: 27 YNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIP-KVELQISIYGVKIL--- 82
Query: 741 GGPEFQRCSHFFQMKNISFCGCHPRNSCYFGFITKHPLLSRFACHVFVSQESMRPVAQSV 800
P+ + H Q+ ISFC + F FI K ++ C+VF S++ + ++
Sbjct: 83 -EPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTI 141
Query: 801 GRAFLEYYQEHL 812
G+AF Y++ L
Sbjct: 142 GQAFDLAYRKFL 153
>gi|239753314 PREDICTED: similar to RIKEN cDNA C230030N03 [Homo
sapiens]
Length = 1183
Score = 55.1 bits (131), Expect = 3e-07
Identities = 119/473 (25%), Positives = 162/473 (34%), Gaps = 92/473 (19%)
Query: 89 EEDDEDEEEEEEEEEGDGE-GQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 147
EE + E G GE G E G A A G P++E P P LR G
Sbjct: 660 EEPPGERLRGESRSSGSGERGPEEAPEGGAAAARGQRPRVPALEPPQP--PRGLRK---G 714
Query: 148 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDT-----GPGGAQSPVRP 202
AQ+ RP + T+ P A E PG +PA T G G + R
Sbjct: 715 AQEPGK--------RPTFSKVTSFRKGRPLAT-ESPGGVPAPTTEGRRWGSSGPEGLPRE 765
Query: 203 GCDCEGNRPAEPPAPGGTS--PSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAG 260
R A P G S P P D R+ G G +S +L S G SE
Sbjct: 766 NPPAAAGRDAPPLHHGDASAWPEFVPQAAGD-RTAGPAGAGHTGTSGDLGSRGPSSESCN 824
Query: 261 GARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEA--------SSPASEPEPPR- 311
RL TE +L + + S+ + + + E SSP E E R
Sbjct: 825 AKRL-------KTTEKKLRARLALAHKTFSNFIESIVLEKENTHERSPSSPKGEKEKSRL 877
Query: 312 --------------EPPRRPAF--LPVGPD-----DTNSEYESGSESEPDL------SED 344
P++P LP+GP+ +T+S E +E + +
Sbjct: 878 RQGSWRAFLKSKDAGSPKKPTLVSLPLGPEVLSPAETDSHCEERAEDKEGYVFSDHWAPP 937
Query: 345 ADSPWLLSNLVSRMISEGSSP-IRCP-----GQCLSPAPRP-------PGEPVSPAGGAA 391
S L S+LVS S P I+C G+ L P PG P + G A
Sbjct: 938 LASTPLSSSLVSPEHRRKSEPTIKCTATQEGGRYLPSGIFPEKSWLASPGSPRAQQAGIA 997
Query: 392 QDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPG--------PAQPGPCLFLSNPTR 443
A + + T C P P P +PRP P + +S +
Sbjct: 998 HTLPSSSACC----LAYENPGTPCRPTSPKPLSPRPSAQRMGLHYPGRGSAISMVSLGSY 1053
Query: 444 DTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGP 496
+ P R P S S + +D+++EE E G P G GT P
Sbjct: 1054 SYVDSSSGDPERPKIPKGQTSFLLSLQTLNQDEQKEESREGGQG-PRGLGTVP 1105
Score = 40.8 bits (94), Expect = 0.005
Identities = 77/353 (21%), Positives = 121/353 (34%), Gaps = 58/353 (16%)
Query: 173 SPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPG----------GTSP 222
SPAP +L GP+PA +G Q P +PG + P+ G S
Sbjct: 380 SPAPT---QLSGPIPAFQSGAPHLQGPCKPGGFRLQRASQDTPSAGLLGENQLRQDSRSC 436
Query: 223 SSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELEL---S 279
+ ++L S+ + SP S +++ G +L + ET+ L S
Sbjct: 437 LVASCLTSELVKLSAEEVPEPAECKSEQSPESRTQEPQGTQLAPRAADERETQKHLWGIS 496
Query: 280 SDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVG--------PDDTNSEY 331
G+ +S +S S EE+ SP + + PR+P + G D +++
Sbjct: 497 VQAGNQTSNYTSKYVLS-EESKSP-TRAKFPRQPSSEGTQVWSGDLMGCLEVSDSSDAPE 554
Query: 332 ESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCP-----GQCLSPAPRPPGEPVSP 386
+ S D S+ A+ +L + +G S + G + PG +P
Sbjct: 555 TTQKSSAIDTSKAAEEAMVLDPIYREQALQGLSEFKAATVSHCGPGAEEGEQGPGGGKTP 614
Query: 387 AGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTI 446
AG + P AG G ++ V AA P+ P
Sbjct: 615 AGNECELPAAPIQGAGDGALQRVAQAAELGRVLVPQAASEETPSTEEP------------ 662
Query: 447 TPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAP 499
PG R G + S+ E EE E G+ RG P P
Sbjct: 663 ------PGERLR-GESRSSGSGERGPEEAPE--------GGAAAARGQRPRVP 700
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 55.1 bits (131), Expect = 3e-07
Identities = 109/479 (22%), Positives = 149/479 (31%), Gaps = 125/479 (26%)
Query: 28 SLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSEQPHPICSFQDDFQEFEMIDDN 87
+L+EFD L + DD G + D+ EK F D+ + ++
Sbjct: 311 NLKEFDQ--LDQENDDGWAGAHEEVDYTEK--------------LKFSDEEDGRDSDEEG 354
Query: 88 EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 147
E + + EE + +G++G P SE P P T
Sbjct: 355 AEGHRDSQSASGEERPPEADGKKGNSPNSEPPTP----------------------KTAW 392
Query: 148 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCE 207
A+ S RP ET PAP+ PLP GP G P D
Sbjct: 393 AETS----------RPP---ETEPGPPAPKP------PLPPPHRGPAGNWGPPGDYPD-R 432
Query: 208 GNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG------RGGRRSSQELSSPGSDSEDAGG 261
G P +PPAP + R +SS R RR +E + A
Sbjct: 433 GGPPCKPPAP-----EDEDEAWRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACA 487
Query: 262 ARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLP 321
+L R+ + L ++ + + S+PA P P+E P PA P
Sbjct: 488 EKLKRLDEKFGAPDKRLKAEPAAPPAA-----------PSTPAPPPAVPKELPAPPAPPP 536
Query: 322 VGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVS-----RMISEGS---SPIRC----- 368
+E E +++ P S LVS S GS SP+
Sbjct: 537 ASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSK 596
Query: 369 ----PGQCLSPAPRPPGEPVSPAG-GAAQDSQDPEAAAG--------PGGVELVDMETL- 414
P + + P PP V P G G Q P G P + E L
Sbjct: 597 EGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLL 656
Query: 415 --------------CAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARP 459
APP P P P P QP + P P PG RP
Sbjct: 657 KQQQQHQWQQHQQGSAPPTPVP----PSPPQPVTLGAVPAPQAPPPPPKALYPGALGRP 711
Score = 37.7 bits (86), Expect = 0.044
Identities = 61/235 (25%), Positives = 87/235 (37%), Gaps = 31/235 (13%)
Query: 111 GGDPGSEAPAP-GPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQET 169
GG P + P P PSP P ++ P + + L + G + +++
Sbjct: 1494 GGHPRHKPGLPQAPQGPSP--RPPTRYEPQRVN-SGLSSDPHFEEPGPMVRGVGGTPRDS 1550
Query: 170 ALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIE 229
A SP P RE P P Q P G ++P PG + S D G E
Sbjct: 1551 AGVSPFPPKRRERPPRKPEL------LQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTE 1604
Query: 230 A------DLRSRSSGGRGGRRSSQE-LSSPGSDSEDAGGARLGRMISSISET-ELELSSD 281
A + ++ + R SS E P S ED G + + S + + + ++SS
Sbjct: 1605 ALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSG 1664
Query: 282 GGSSSSGRSSHLTNSIEE------ASSPAS----EPEPPREPPRRPAFLPVGPDD 326
S S L + E SSP + E P EPPRRP P P D
Sbjct: 1665 PCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRP---PPAPHD 1716
Score = 35.8 bits (81), Expect = 0.17
Identities = 65/281 (23%), Positives = 89/281 (31%), Gaps = 44/281 (15%)
Query: 80 EFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPT 139
E+E I + + E E + +E P PL P P P P
Sbjct: 1093 EYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPS---PA 1149
Query: 140 TLRLTTLGAQ-------DSLNNNGGFDLVRPASWQETALCSPAPEALRELP--GPLPATD 190
R T G + S GG RP PA + P GPLP +
Sbjct: 1150 PARFTARGGRVFTPRGVPSRRGRGGG---RPPPQVCPGWSPPAKSLAPKKPPTGPLPPSK 1206
Query: 191 TGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELS 250
+ + PG P P A GG++ S+ G+E R R R GR Q+
Sbjct: 1207 EP---LKEKLIPG-------PLSPVARGGSNGGSNVGMEDGERPRRR--RHGRAQQQD-- 1252
Query: 251 SPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPP 310
+ R E E G S + E ++ P P
Sbjct: 1253 ------------KPPRFRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPR 1300
Query: 311 REPPRRPAFLPVGPDDTNSEYESGSESEPDLSE---DADSP 348
R + P D N E+E+ SES SE D ++P
Sbjct: 1301 RAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP 1341
Score = 34.7 bits (78), Expect = 0.37
Identities = 92/405 (22%), Positives = 127/405 (31%), Gaps = 107/405 (26%)
Query: 99 EEEEEGDGEGQEGGDPGSEAPA--PGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNG 156
++E E G EG P PA PGP +V R + L Q+S N
Sbjct: 1261 KQERENAARGSEG-KPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANE 1319
Query: 157 GFDLVRPAS--WQETALCSPAPEALRELPGPLPATDTGPGGAQ----------------- 197
++ +S E AP + P + G GGA
Sbjct: 1320 EWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKD 1379
Query: 198 ------SPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRS------ 245
S RPG + + RP P G+S SS G R+ GRG +RS
Sbjct: 1380 LSKRSFSSQRPGMERQNRRPG-PGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKN 1438
Query: 246 --------SQELSSPGSDSEDAGGARLGRMISS----ISETELELSSDGGS--SSSGRSS 291
L P + RL ++I S I + +LSS GS + G
Sbjct: 1439 RSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPR 1498
Query: 292 HLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLL 351
H + P+ P EP R SG S+P E
Sbjct: 1499 HKPGLPQAPQGPSPRPPTRYEPQR---------------VNSGLSSDPHFEEPG------ 1537
Query: 352 SNLVSRMISEGSSPIRCPGQCLSPAP-----RPPGEPVSPAGGAAQDSQDPEAAAGPGGV 406
+ G +P G +SP P RPP +P
Sbjct: 1538 ----PMVRGVGGTPRDSAG--VSPFPPKRRERPPRKP----------------------- 1568
Query: 407 ELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITP-LW 450
EL+ E+L PPP + P PGP + + +TP +W
Sbjct: 1569 ELLQEESL--PPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIW 1611
Score = 32.7 bits (73), Expect = 1.4
Identities = 67/274 (24%), Positives = 88/274 (32%), Gaps = 39/274 (14%)
Query: 174 PAPEALRELPG-PLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADL 232
P P + ELP PL D P + + P E P G SP+ P + D
Sbjct: 956 PPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPA--PRLRRDY 1013
Query: 233 RSRSSGG---RGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGR 289
G RG R G G R R S E G + G
Sbjct: 1014 SYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGP 1073
Query: 290 SSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSES-EPDLS-EDADS 347
+ AS SE E P+R E+GSE+ E DL+ D ++
Sbjct: 1074 NHPPAPRGRTASETRSEGSEYEEIPKRRR---------QRGSETGSETHESDLAPSDKEA 1124
Query: 348 PWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPA-------GGAAQDSQDPEAA 400
P ++++ P+ AP PPG P SPA GG + +
Sbjct: 1125 PTPKEGTLTQV------PL---------APPPPGAPPSPAPARFTARGGRVFTPRGVPSR 1169
Query: 401 AGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGP 434
G GG PP AP+ P P P
Sbjct: 1170 RGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLP 1203
Score = 32.0 bits (71), Expect = 2.4
Identities = 96/396 (24%), Positives = 129/396 (32%), Gaps = 83/396 (20%)
Query: 174 PAPEALRELPGPLPAT-DTGPGGAQSPV----------RPG-CDCEGNRPAEPPAPG--- 218
P P+ L+ G L +T P G SP R G C G E A G
Sbjct: 979 PKPDPLKITKGKLGGPKETPPNGNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGF 1038
Query: 219 -GTSPSSDPGIEA-DLRS----RSSGGRGGR------------RSSQELSSPGSDSEDAG 260
GT G + + RS R GRGG R++ E S GS+ E+
Sbjct: 1039 RGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIP 1098
Query: 261 GARLGRMISSISET-ELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPA- 318
R R + SET E +L+ + + + LT P + P P P R A
Sbjct: 1099 KRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPSPA--PARFTAR 1156
Query: 319 ----FLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLS 374
F P G G P + P ++ +P + P L
Sbjct: 1157 GGRVFTPRGVPSRRGR--GGGRPPPQVCPGWSPP-----------AKSLAPKKPPTGPLP 1203
Query: 375 PAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP-------------PP-- 419
P+ P E + P P A G G V ME P PP
Sbjct: 1204 PSKEPLKEKLIPG------PLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRF 1257
Query: 420 -----PAPAAPRPGPAQPGPCLFLSNP-TRDTITPLWAAPGRAARPGRACSAACSEEEDE 473
A R +P L S P + +T + AP A R A S S + +
Sbjct: 1258 RRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVAP--APRRAAAKSPDLSNQNSD 1315
Query: 474 EDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAV 509
+ +EE E A +S+ R AP L AV
Sbjct: 1316 QANEEWETASESSDFTSERRGDKEAPPPVLLTPKAV 1351
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 54.7 bits (130), Expect = 3e-07
Identities = 124/564 (21%), Positives = 191/564 (33%), Gaps = 104/564 (18%)
Query: 61 SLGRSEQPHPICSFQDDFQEFEMIDDNEEEDD---EDEE------------EEEEEEEGD 105
+LG+ E + S +++ QE D + +D +D+E E E+E E +
Sbjct: 922 NLGKGEYQESLRSLEEEGQELPQSADVQRWEDTVEKDQELAQESPPGMAGVENEDEAELN 981
Query: 106 GEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLR-LTTLGAQDSLNNNGGFDLVRPA 164
Q+G E G L + V P + P + G + + GG + ++
Sbjct: 982 LREQDGFTGKEEVVEQGELNATEEVWIPGEGHPESPEPKEQRGLVEGASVKGGAEGLQDP 1041
Query: 165 SWQETALCSP---APEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTS 221
Q + +P AP+ L E PL D PGG Q+ G+ PA + G
Sbjct: 1042 EGQSQQVGAPGLQAPQGLPEAIEPLVEDDVAPGGDQASPEV---MLGSEPAMGESAAGAE 1098
Query: 222 PSSDPGIEADLRSRSSGGRG--GRRSSQELSSPGSDSEDAGGARLGRMISSISETELELS 279
P G+ GG G G + +E+ P + E R + + +L
Sbjct: 1099 PGPGQGV---------GGLGDPGHLTREEVMEPPLEEESLEAKR----VQGLEGPRKDLE 1145
Query: 280 SDGGSSSSGRSSHLTNSIEEASSPASEP-EPPREPPRRPAFLPVGPDDTNSEYESGSESE 338
GG L E + +P EPPRE G +++ +E G+E
Sbjct: 1146 EAGG---------LGTEFSELPGKSRDPWEPPRE----------GREESEAEAPRGAEEA 1186
Query: 339 ------PDLSEDADSPWLLSNLVSR----MISEGSSPIRCPGQCLSPAPRPPGEPVSPAG 388
DA SPW L + + + SP P +P P+P E A
Sbjct: 1187 FPAETLGHTGSDAPSPWPLGSEEAEEDVPPVLVSPSPTYTPILEDAPGPQPQAEGSQEAS 1246
Query: 389 GAAQ---------DSQDPEAAAG--PGGVELVDMETLCAPPPPAPAAPRPGPAQPGPCLF 437
Q +S+ E +G P G + E+ P G +
Sbjct: 1247 WGVQGRAEALGKVESEQEELGSGEIPEGPQEEGEESREESEEDELGETLPDSTPLG--FY 1304
Query: 438 LSNPTRDTITPLWAAPGRAARPGRACSA---------------ACSEEEDEEDDEEEEDA 482
L +PT +P W G P + + A E++E ++ EEE
Sbjct: 1305 LRSPT----SPRWDPTGEQRPPPQGETGKEGWDPAVLASEGLEAPPSEKEEGEEGEEECG 1360
Query: 483 EDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGG 542
DS S G AP + + + V + R G EE+SG
Sbjct: 1361 RDSDLSEEFEDLGTEAPFLPGVPGEVAEPLGQVPQLLLDPAAWDRDGESDGFADEEESGE 1420
Query: 543 EASEE-----EAGAALLGGGQVSG 561
E E+ E GA G G G
Sbjct: 1421 EGEEDQEEGREPGAGRWGPGSSVG 1444
Score = 35.4 bits (80), Expect = 0.22
Identities = 45/174 (25%), Positives = 65/174 (37%), Gaps = 29/174 (16%)
Query: 86 DNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLI-----------------PSP 128
D + E D +EEE EEG+ + +EG +PG+ PG + S
Sbjct: 1404 DRDGESDGFADEEESGEEGEEDQEEGREPGAGRWGPGSSVGSLQALSSSQRGEFLESDSV 1463
Query: 129 SVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAP-EALRELPGPLP 187
SV P +LR GA + D P+ +E + P E ++PGPL
Sbjct: 1464 SVSVPW---DDSLRGAVAGAPKTALETESQDSAEPSGSEEES--DPVSLEREDKVPGPLE 1518
Query: 188 ATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRG 241
P G + PG D G + P G S + G+ L G+G
Sbjct: 1519 I----PSGMED-AGPGADIIGVN-GQGPNLEGKSQHVNGGVMNGLEQSEEVGQG 1566
Score = 32.0 bits (71), Expect = 2.4
Identities = 64/248 (25%), Positives = 84/248 (33%), Gaps = 65/248 (26%)
Query: 82 EMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAP-APGPLIPSPSVEEPHKHRPTT 140
E ++ E +E EE EEE +E D G+EAP PG +P V EP
Sbjct: 1340 EGLEAPPSEKEEGEEGEEECGRDSDLSEEFEDLGTEAPFLPG--VPG-EVAEP------- 1389
Query: 141 LRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPV 200
LG L L+ PA+W E G ++G G
Sbjct: 1390 -----LGQVPQL-------LLDPAAWDRDG----------ESDGFADEEESGEEGE---- 1423
Query: 201 RPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGG--RRSSQELSSPGSDSED 258
E P G P S G L++ SS RG S +S P DS
Sbjct: 1424 ------EDQEEGREPGAGRWGPGSSVG---SLQALSSSQRGEFLESDSVSVSVPWDDS-- 1472
Query: 259 AGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPA 318
L ++ +T LE S + SG EE S P S + P P
Sbjct: 1473 -----LRGAVAGAPKTALETESQDSAEPSGS--------EEESDPVSLEREDKVP--GPL 1517
Query: 319 FLPVGPDD 326
+P G +D
Sbjct: 1518 EIPSGMED 1525
Score = 31.2 bits (69), Expect = 4.1
Identities = 24/83 (28%), Positives = 30/83 (36%)
Query: 196 AQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSD 255
A R G + + PAP P+ P +E R RG R QE +
Sbjct: 143 AHEEERVGLNAQAACAPRCPAPPRGPPAPAPEVEELARRLGEAWRGAVRGYQERVAHMET 202
Query: 256 SEDAGGARLGRMISSISETELEL 278
S RLGR + E LEL
Sbjct: 203 SLGQARERLGRAVQGAREGRLEL 225
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 54.7 bits (130), Expect = 3e-07
Identities = 91/370 (24%), Positives = 130/370 (35%), Gaps = 65/370 (17%)
Query: 88 EEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLG 147
EEE++E E EE GQ+ P P PGP P P P R RL
Sbjct: 261 EEENEEKPLLEVSPEERPSSGQQDVAP-DRGPEPGPPAPLP---PPGGARARRARLQHSS 316
Query: 148 AQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCE 207
A + GG P+S PA L E P + P PG D
Sbjct: 317 ALTASVEEGGVPGEDPSS-------RPATPELAEPESAPTLRVEPPSPPEGPPNPGPD-G 368
Query: 208 GNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRM 267
G + E P G +P++D E + ++++SP + G
Sbjct: 369 GKQDGEAPPAGPCAPATDKAEEVVC------------APEDVASPFPTAIPEGD------ 410
Query: 268 ISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDT 327
++ ET+ +S+ S+ G + E +P P+ + PP PA P +T
Sbjct: 411 -TTPPETDPAATSEAPSARDGPERSVPKEAE--PTPPVLPDEEKGPP-GPAPEPEREAET 466
Query: 328 NSEYESGSE-----SEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGE 382
E +G+E +EP + P S L R + P P L+ A PP E
Sbjct: 467 EPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPP--LAAAESPPVE 524
Query: 383 P--------------------VSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAP 422
P +P GA + + PE A GG EL +
Sbjct: 525 PGPGSLDAEAAAPERPKAERAEAPPAGAERAA--PERKAERGGAELRGAKKFSV--SSCR 580
Query: 423 AAPRPGPAQP 432
A PRPG ++P
Sbjct: 581 ARPRPGVSRP 590
Score = 41.6 bits (96), Expect = 0.003
Identities = 85/332 (25%), Positives = 111/332 (33%), Gaps = 49/332 (14%)
Query: 172 CSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSP--SSDPGIE 229
C+P E E P + + P Q V P E PA P PGG +
Sbjct: 257 CTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSS 316
Query: 230 ADLRSRSSGGRGGRRSSQELSSPG-SDSEDAGGARLGRMISSISETELELSSDGGSSS-- 286
A S GG G S ++P ++ E A R+ S E DGG
Sbjct: 317 ALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEP--PSPPEGPPNPGPDGGKQDGE 374
Query: 287 ---SGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSE 343
+G + T+ EE PE P P +P G D T E + + SE +
Sbjct: 375 APPAGPCAPATDKAEEV---VCAPEDVASP--FPTAIPEG-DTTPPETDPAATSEAPSAR 428
Query: 344 DADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGP 403
D R + + + P P PPG P A +PE AG
Sbjct: 429 DGP---------ERSVPKEAEP--TPPVLPDEEKGPPGPAPEPEREA---ETEPERGAGT 474
Query: 404 GGVEL-VDMETLCAPPPPAPAA---PRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARP 459
+ + T AP PPAP + RP A GP ++P PL AA P
Sbjct: 475 EPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPA---ASP------PLAAAESPPVEP 525
Query: 460 GRACSAACSEEEDEEDDEEEEDAEDSAGSPGG 491
G A E E AE + P G
Sbjct: 526 GPGSLDA------EAAAPERPKAERAEAPPAG 551
Score = 34.7 bits (78), Expect = 0.37
Identities = 90/442 (20%), Positives = 137/442 (30%), Gaps = 45/442 (10%)
Query: 92 DEDEEEEEEEEEGDG-EGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTT-----LRLTT 145
+ + E E E E G G E + G S APAP P P + KHRP
Sbjct: 459 EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCL----KHRPAAASEGPAASPP 514
Query: 146 LGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCD 205
L A +S G P S A P+A R P A P + R G +
Sbjct: 515 LAAAESPPVEPG-----PGSLDAEAAAPERPKAERAEAPPAGAERAAP--ERKAERGGAE 567
Query: 206 CEGNRP------AEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDA 259
G + P PG + P L R P
Sbjct: 568 LRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP 627
Query: 260 GGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAF 319
G +L ++ +S G S + + E A EP P + R P
Sbjct: 628 GPRKLAE--RGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSED--RNPFP 683
Query: 320 LPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRP 379
+ + + +Y G+ E + + L ++ + E P+ +PA R
Sbjct: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLG-----TAPALRG 738
Query: 380 PGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQP--GPCLF 437
P G A+ + + L+ TL P PAP PG +P P
Sbjct: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTL--PHQPAPPDAGPGEREPRKEPRTA 796
Query: 438 LSNPTR----DTITPLWAAPGRAARPGRACSAACSEE-----EDEEDDEEEEDAEDSAGS 488
P R ++ P PG +P ++ + + E++ A
Sbjct: 797 EKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSE 856
Query: 489 PGGRGTGPSAPRDASLVYDAVK 510
PG + P ++ D V+
Sbjct: 857 PGKQAKVPERGQEPVKQADFVR 878
Score = 31.6 bits (70), Expect = 3.1
Identities = 76/316 (24%), Positives = 95/316 (30%), Gaps = 111/316 (35%)
Query: 298 EEASSPASEPEPPREPPRRPAFLPVGP---------------DDTNSEYESGSESEP--D 340
E+A + + PR PP VGP D T S S + P D
Sbjct: 149 EDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNSLAPVAD 208
Query: 341 LSEDADSPWLLSN---------------------LVSRMISEGSSPIRC----------P 369
S A+S L N L SR SE S + C P
Sbjct: 209 FSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKP 268
Query: 370 GQCLSPAPRP----------------PGEPVSPAGGA------AQDSQDPEAAAGPGGV- 406
+SP RP P P+ P GGA Q S A+ GGV
Sbjct: 269 LLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVP 328
Query: 407 -----------ELVDMETL----CAPPPPAPAAPRPGP--------AQP-GPCLFLSNPT 442
EL + E+ PP P P PGP A P GPC ++
Sbjct: 329 GEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKA 388
Query: 443 -------RDTITPL-WAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSP----- 489
D +P A P P AA SE D E +++ +P
Sbjct: 389 EEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPD 448
Query: 490 ---GGRGTGPSAPRDA 502
G G P R+A
Sbjct: 449 EEKGPPGPAPEPEREA 464
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 54.7 bits (130), Expect = 3e-07
Identities = 143/573 (24%), Positives = 194/573 (33%), Gaps = 124/573 (21%)
Query: 25 QDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDS-----LSLGRSEQPHPICSFQDDFQ 79
+D ++ DD D SE DD LS S+ E DS +S+ S+ S +
Sbjct: 1061 EDDDDDDSDDRDESE-NDDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESS 1119
Query: 80 EFEMIDDN--------------EEEDDEDEEEEEEEEEGDGEGQEGGDPGSE--APAPG- 122
EFE ++ EEE++E+EEE EE G E + E A APG
Sbjct: 1120 EFESSSESSPSSSEDEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGA 1179
Query: 123 PLIPSPSVEE---------PHKHRPTTLRLTTL--GAQDSLNNNGGFDLVRPASWQETA- 170
P + S +EE + RP+ L L G ++ ++ + P QE A
Sbjct: 1180 PAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPE--EPGLSQEGAM 1237
Query: 171 LCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAP---GGTSPSSDPG 227
L SP P A +E+ P + V P P +PP P PS P
Sbjct: 1238 LLSPEPPA-KEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPPE 1296
Query: 228 IEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSS 287
E S S +PG G + S S + + G S
Sbjct: 1297 PETTDASHPSVPPEPLAEDHPPHTPG---------LCGSLAKSQSTETVPATPGGEPPLS 1347
Query: 288 GRSSHLT-NSIEEASSPASEPEP---------PREP------------PRRPAFLPVGPD 325
G SS L+ +S + SP S P P PR P P P LPV P
Sbjct: 1348 GGSSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPL 1407
Query: 326 DTNSEYE-SGSESEPDLSEDA-------DSPWLLSNLVSRMISEGSSPIRCP-------G 370
T E SG + P L E P L+ L + + ++ +P P
Sbjct: 1408 PTGRRDERSGPLASPVLLETGLPLPLPLPLPLPLA-LPAVLRAQARAPTPLPPLLPAPLA 1466
Query: 371 QCLSPAPRPPGEP--------------VSPAGGAAQDSQ------DPEAAAGPGGVE--- 407
C P R PG P V P GAA + P+ P +
Sbjct: 1467 SCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRT 1526
Query: 408 -LVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAA 466
+D P PP P P+P P P P + + + W P A PG
Sbjct: 1527 VTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQW--PSEAIPPGPRGRDE 1584
Query: 467 CSEEEDE----------EDDEEEEDAEDSAGSP 489
+EE E + ED AGSP
Sbjct: 1585 VTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSP 1617
Score = 44.7 bits (104), Expect = 4e-04
Identities = 79/389 (20%), Positives = 128/389 (32%), Gaps = 55/389 (14%)
Query: 63 GRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGD--------GEGQEGGDP 114
G ++ + Q+ +E E ++ EEE+D+D+++ ++ +E + E E +
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEG 1092
Query: 115 GSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSP 174
S+ ++ S + + + ++ ++V +E
Sbjct: 1093 DSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM 1152
Query: 175 APEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRS 234
E GP G A +P P D G +P P + D
Sbjct: 1153 VAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM-LDEPP 1211
Query: 235 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 294
G S + PG E G M+ S E+ + S H
Sbjct: 1212 LPVGVEEPADSREPPEEPGLSQE-------GAMLLSPEPPAKEVEARPPLSPERAPEHDL 1264
Query: 295 NSIEEASS----PASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWL 350
E P P PP PPR P+ P P+ T++ + S EP L+ED
Sbjct: 1265 EVEPEPPMMLPLPLQPPLPPPRPPRPPS-PPPEPETTDASHPS-VPPEP-LAED------ 1315
Query: 351 LSNLVSRMISEGSSPIRCPGQCLSPAPRPPGE--PVSPAGGAAQDSQDPEAAAGPGGVEL 408
P PG C S A E P +P G +P + G G+ L
Sbjct: 1316 -------------HPPHTPGLCGSLAKSQSTETVPATPGG-------EPPLSGGSSGLSL 1355
Query: 409 VDMETLCAP---PPPAPAAPRPG-PAQPG 433
+ +P P P+P+ G P PG
Sbjct: 1356 SSPQVPGSPFSYPAPSPSLSSGGLPRTPG 1384
Score = 38.9 bits (89), Expect = 0.020
Identities = 96/374 (25%), Positives = 120/374 (32%), Gaps = 77/374 (20%)
Query: 114 PGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCS 173
P PAPG + P H P T A ++G F PA
Sbjct: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRA-PAP----PPLP 438
Query: 174 PAPEALRELPG-----PLPATDTGPGGAQ-----SPVRPGCDCEGNRPAEPPAPGGTSP- 222
PA +E PG P P T++ G + SP CD G E G P
Sbjct: 439 PAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSP--EPCDSPGTPTLESSPAGPEKPH 496
Query: 223 -SSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSD 281
S D IE L+ + R L P SD+E G ISS S L+
Sbjct: 497 DSLDSRIEMLLKEQ-------RTKLLFLREPDSDTELQ---MEGSPISSSSSQLSPLAPF 546
Query: 282 GGSS----------SSGRSSHLTNSIEEASSPASE----------PEPPREP-PRRPAFL 320
G +S SS SS I P S+ P PP EP P PA L
Sbjct: 547 GTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGL 606
Query: 321 ----------------PVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMI-SEGS 363
P + SG + E E +P ++ M+ + G+
Sbjct: 607 LSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGA 666
Query: 364 SPIRCPGQCLS--PAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPA 421
+ + P P P PPG P P P PG + PPPPA
Sbjct: 667 AAVAAPSVLAPTLPLPPPPGFPPLPP-------PPPPPPPQPGFPMPPPLPPPPPPPPPA 719
Query: 422 -PAAPRPGPAQPGP 434
PA P P P P
Sbjct: 720 HPAVTVPPPPLPAP 733
Score = 35.8 bits (81), Expect = 0.17
Identities = 24/82 (29%), Positives = 38/82 (46%)
Query: 468 SEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLR 527
S EE+EE +EEEE+ +D R + D +L + K DE + +V+ +
Sbjct: 1047 STEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKDEGDSDEEETVSIVTSK 1106
Query: 528 RCAGLGHDSEEDSGGEASEEEA 549
A +S E S E+S E +
Sbjct: 1107 AEATSSSESSESSEFESSSESS 1128
>gi|189181750 human immunodeficiency virus type I enhancer binding
protein 3 b [Homo sapiens]
Length = 2405
Score = 54.3 bits (129), Expect = 5e-07
Identities = 89/347 (25%), Positives = 127/347 (36%), Gaps = 59/347 (17%)
Query: 80 EFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPT 139
+F ++D++ + D DE+E+E+EEE E P SEAP PGP PH R
Sbjct: 1846 QFSDLEDSDSDSDLDEDEDEDEEESQDELSR---PSSEAPPPGP---------PHALRAD 1893
Query: 140 TLRLTTLGAQDSLNNNGGFDLVRPASWQE-----TALCSPAPEALRELP--GPLP----A 188
+ + LG Q G + R +S E + CS + +++ LP GP P
Sbjct: 1894 SSPI--LGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVE 1951
Query: 189 TDTGPGGAQSPVRPGCDCEGNRPA--EPP------------APGGTSPSSDPGIEADLRS 234
DTG + PV P ++ A PP +P SP+ +P A
Sbjct: 1952 KDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPP 2011
Query: 235 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 294
G + SP LGR ++ + LS G++ G +
Sbjct: 2012 GLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHV---LSKLEGTTDPGLPRY-- 2066
Query: 295 NSIEEASSPASEPEPPRE-PPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSN 353
S SP PPR PP + A GP S E P L D + +
Sbjct: 2067 -SPTRRWSPGQAESPPRSAPPGKWAL--AGPGS-----PSAGEHGPGLGLDPRVLFPPAP 2118
Query: 354 LVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAA 400
L +++S R P C SP P G A S P +A
Sbjct: 2119 LPHKLLS------RSPETCASPWKAESRSPSCSPGPAHPLSSRPFSA 2159
Score = 41.6 bits (96), Expect = 0.003
Identities = 82/337 (24%), Positives = 114/337 (33%), Gaps = 49/337 (14%)
Query: 98 EEEEEEGDGEGQEGGD-PGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNG 156
E+ + G EG D P ++ P+P P +P H +P +R + + L
Sbjct: 807 EKSDSLEQPSGLEGEDKPLAQFPSPPP---APHGRSAHSLQPKLVRQPNIQVPEILVTE- 862
Query: 157 GFDLVRPASWQETALCSPAPEALRELPGP--------LPATDTGPGGAQSPVRPGCDCEG 208
+ RP + E PE E P LPA P + + G
Sbjct: 863 --EPDRPDTEPEPP--PKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSG 918
Query: 209 NRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSD--SEDAGGARLGR 266
E P SPS + + SRS+ E SP SD + G L
Sbjct: 919 ESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978
Query: 267 MISSISETELELSSDGGSSSSGRSSHLTN-----------SIEEASSPASEPEPPR--EP 313
E+ S+ S + S+H+T S+ S+PA P R P
Sbjct: 979 PSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPP 1038
Query: 314 PRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPW----------LLSNLVSRMISEGS 363
RR FL V + ES E P ++++ P LS + S S G
Sbjct: 1039 ERRKCFL-VRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGG 1097
Query: 364 SP-IRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEA 399
P + PGQ RPP P P A Q P A
Sbjct: 1098 PPGGKGPGQ-----DRPPLGPTVPYTEALQVFHHPVA 1129
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 53.9 bits (128), Expect = 6e-07
Identities = 91/382 (23%), Positives = 129/382 (33%), Gaps = 51/382 (13%)
Query: 87 NEEEDDEDEEEEEEEEEGDGEGQEGGDP----GSEAPAPGPLIPSPSVEEPHKHRPTTLR 142
N D E E D GQ G P G++ P PGP P P + P PT
Sbjct: 743 NNSSDTESIPSPHTEAAKD-TGQNGPKPPATLGADGPPPGPPTPPPE-DIPAPTEPTPAS 800
Query: 143 LTTLGAQDSLNNNGGFDLVRPA-----SWQETALCSPAPEALRELPGPLPATDTGPGGAQ 197
T GA P +ETA P E + P G A+
Sbjct: 801 EAT-GAPTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAE 859
Query: 198 SPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDS- 256
PV+ C E E PA G + +++ E L++ G GR ++ + S DS
Sbjct: 860 EPVKSECTEEAE---EGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 916
Query: 257 ----------EDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASS---- 302
++A G R++S ++S + L + A++
Sbjct: 917 SSATCSADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPI 976
Query: 303 PASEPEPPRE--PPRRPAFLPVGPDDTNSEYESGSESEPDLS-------------EDADS 347
EPPRE P +PA P P N + ES + +P S ++A+
Sbjct: 977 VTKVHEPPREDAAPTKPA-PPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEK 1035
Query: 348 PWLLSNLVSRMIS-EGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAG-PGG 405
P + G P G P P PP E + + A S A G P
Sbjct: 1036 PVFFPAFAAEAQKLPGDPPCWTSG---LPFPVPPREVIKASPHAPDPSAFSYAPPGHPLP 1092
Query: 406 VELVDMETLCAPPPPAPAAPRP 427
+ L D P PP + P P
Sbjct: 1093 LGLHDTARPVLPRPPTISNPPP 1114
Score = 37.4 bits (85), Expect = 0.057
Identities = 64/283 (22%), Positives = 97/283 (34%), Gaps = 43/283 (15%)
Query: 292 HLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLL 351
H +E ++ + + P AF PV +D E S +E ++ E+A++
Sbjct: 669 HKLKMEKERNARRKKKKAPAAASEEAAFPPV-VEDEEMEASGVSGNEEEMVEEAEALHAS 727
Query: 352 SNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAG----PGGVE 407
N V R G + + S P P E G Q+ P A G P G
Sbjct: 728 GNEVPRGECSGPATVNNSSDTES-IPSPHTEAAKDTG---QNGPKPPATLGADGPPPGPP 783
Query: 408 LVDMETLCAP--------------PPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAP 453
E + AP PPPAP P P+ P P + +T
Sbjct: 784 TPPPEDIPAPTEPTPASEATGAPTPPPAP----PSPSAPPPVVPKEEKEEETAAAPPVEE 839
Query: 454 GRAARPGRACSAACSEEEDEEDDEEE--EDAEDSAGSPGGRGTGPSAPRDASLVYDAVKY 511
G +P A A + EE + E E+AE+ GP+ +DA +
Sbjct: 840 GEEQKPPAAEELAVDTGKAEEPVKSECTEEAEE----------GPAKGKDAEAAEATAEG 889
Query: 512 TLVVD-EHTQLELVSLRRCAGLGHDSEED---SGGEASEEEAG 550
L + + + + +G DS+ S E E E G
Sbjct: 890 ALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGG 932
Score = 31.2 bits (69), Expect = 4.1
Identities = 65/274 (23%), Positives = 89/274 (32%), Gaps = 62/274 (22%)
Query: 86 DNEEEDDEDEEEEEE------------------EEEGDGEGQEGGDPGSEA-PAP----- 121
D + E D D E E+ E+ G GG GS + PA
Sbjct: 1806 DRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGSSGGGGGSSSRPASHSHAH 1865
Query: 122 --GPLIPSPSVEEPHKHRPTTLRLTTL---------GAQDSLNNNGGFDLVRPASWQETA 170
P+ SP ++ + RP+ L T + L + VRPA+ A
Sbjct: 1866 QHSPI--SPRTQDALQQRPSVLHNTGMKGIITAVEPSTPTVLRSTSTSSPVRPAATFPPA 1923
Query: 171 LCSPAPEALR----ELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 226
P L L P+ P A+ P RP D A+PPA G P+S P
Sbjct: 1924 THCPLGGTLDGVYPTLMEPVLLPKEAPRVAR-PERPRADTGHAFLAKPPARSGLEPASSP 1982
Query: 227 --GIE-----------ADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISE 273
G E A + + +S + +P + + D + SI E
Sbjct: 1983 SKGSEPRPLVPPVSGHATIARTPAKNLAPHHASPDPPAPPASASDPHREKTQSKPFSIQE 2042
Query: 274 TELELSSDGGSSSSGRSSHLTNSIEEASSPASEP 307
EL GSS S E SP S P
Sbjct: 2043 LELRSLGYHGSSYSPEG-------VEPVSPVSSP 2069
Score = 30.4 bits (67), Expect = 7.0
Identities = 33/135 (24%), Positives = 45/135 (33%), Gaps = 35/135 (25%)
Query: 400 AAGPGGV-ELVDMETLCAPPPPAPAAPRPG-------PAQPGPCLFLSNPTRDTITPLWA 451
AAGP G+ +L + L PP P P P P P F S + ++P
Sbjct: 1732 AAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLPTAPQP--FSSRHSSSPLSP--G 1787
Query: 452 APGRAARPGRACSAACSEEEDEEDDEEEE-----------------------DAEDSAGS 488
P +P S+ + D E D + E + S+GS
Sbjct: 1788 GPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVEHAPIWRPGTEQSSGSSGS 1847
Query: 489 PGGRGTGPSAPRDAS 503
GG G S P S
Sbjct: 1848 SGGGGGSSSRPASHS 1862
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 53.5 bits (127), Expect = 8e-07
Identities = 88/352 (25%), Positives = 118/352 (33%), Gaps = 28/352 (7%)
Query: 115 GSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSP 174
G AP P P V P + TT R LG Q L + + R + + +
Sbjct: 100 GERAPPAKNTSPGP-VSSPGRASGTT-RPGPLG-QKGLRISAEETVARGKATEAPKRSAL 156
Query: 175 APEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRS 234
+ A R+ GP P T + P A+ G + RPA P P+ P
Sbjct: 157 SAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPAPSARP--RPPTEGP-------- 205
Query: 235 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 294
R S S+ E S AGG S+S + LSS S S R +
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 295 NSIEEASSPASEP--EPPR-EPPRRPAFLPVGPDDTNSEYESG------SESEPDLSEDA 345
+ P PP+ PPR+ A +GP ++ S++ P L
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325
Query: 346 DSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGG 405
S L L + + SP P P+P P +P A P A
Sbjct: 326 HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP-----PATPPSQATTSLGSPTLQATHSF 380
Query: 406 VELVDMETLCAPPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAA 457
+ + L PPP AP A P Q P S P TP AP A
Sbjct: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432
Score = 43.1 bits (100), Expect = 0.001
Identities = 100/378 (26%), Positives = 137/378 (36%), Gaps = 45/378 (11%)
Query: 111 GGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNN--NGGFDLVRPASWQ- 167
G + G PAP P P E P K + +T + + G L RPAS
Sbjct: 184 GTEVGLPRPAPSAR-PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 168 ---ETALCSPA---PEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT 220
T L SPA P A P + P G Q+ +RP + A P P +
Sbjct: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSS 301
Query: 221 SPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSS 280
SP + P A L+S++ S L+ + A L S + L S
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTC-----QLATPLPLAPPSPSAPPSLQTLPS 356
Query: 281 DGGSSSSGRSSHLTNSIEEASSPASEPEPPREP-----PRRPAFLPVGPDDTNSEYESGS 335
+ S ++ L + +A+ + P PP P P+ P L + P +
Sbjct: 357 PPATPPSQATTSLGSPTLQATH-SFLPSPPLSPLATPPPQAPPALALPP----LQAPPSP 411
Query: 336 ESEPDLSEDAD-SPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDS 394
+ P LS A SP + L ++ SP P +P P PVSP+ A S
Sbjct: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPS--ATPPS 468
Query: 395 QDPEAAAGP------GGVELVDMETLCAPPPPAP---AAPRPGPAQPGPCLFLSNPTRDT 445
Q P + A P M PPP AP AAP A+P P P
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALA 524
Query: 446 ITPLWAAPG-RAARPGRA 462
PL A P A+ PG+A
Sbjct: 525 TPPLQALPSPPASFPGQA 542
Score = 40.4 bits (93), Expect = 0.007
Identities = 43/134 (32%), Positives = 56/134 (41%), Gaps = 22/134 (16%)
Query: 163 PASWQETALCSPAPE-ALRELPG-PLP-ATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGG 219
PA+W PAP A R PG PLP TGPG A + + EG A P APG
Sbjct: 668 PAAWSR----GPAPPLAFRGAPGAPLPWPPATGPGSADG-LCTIYETEGPESATP-APGA 721
Query: 220 TSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSI-----SET 274
P PG +SGG+ + SS G LG + +S+ S T
Sbjct: 722 LDPGPSPG--------TSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRT 773
Query: 275 ELELSSDGGSSSSG 288
L +++G + SG
Sbjct: 774 LLLAAAEGAAGGSG 787
Score = 35.4 bits (80), Expect = 0.22
Identities = 92/392 (23%), Positives = 121/392 (30%), Gaps = 36/392 (9%)
Query: 116 SEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPA 175
S+AP P P S P L + A SL P S T+L SP
Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPATPPSQATTSLGSPT 373
Query: 176 PEALRE-LPGP--LPATDTGPGGAQSPVRPGCDCEGNRPAEPP-APGGT-SPSSDPGIEA 230
+A LP P P P + P + PA PP +P T SP + +
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433
Query: 231 DLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRS 290
L S P S + S++ L++ +S
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 291 SHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWL 350
S A+ P P P PP + A P + + P S +P+
Sbjct: 494 S--------ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF- 544
Query: 351 LSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVD 410
S S SP+ P P P V P+ A+ Q P PG V
Sbjct: 545 -----SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 599
Query: 411 METLC---APPPPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAAC 467
L AP PP P + P GP L + + T TP R G AA
Sbjct: 600 GPRLTLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTP---EELRGYDSGPEGGAAA 655
Query: 468 SEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAP 499
S DAE +A P GP+ P
Sbjct: 656 S---------PPPDAELAACHPAAWSRGPAPP 678
Score = 33.5 bits (75), Expect = 0.83
Identities = 46/165 (27%), Positives = 56/165 (33%), Gaps = 38/165 (23%)
Query: 367 RCPGQCLSPAPRPPGEPVSP------------AGGAAQDSQDPEAAAGPGGVELVDMETL 414
R PG PRPPG P P A GA E A G GG + +
Sbjct: 20 RAPGLL---TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 415 CAPP--------PPAPAAPRPGPAQPGPCLFLSNPTRDTITPLWAAPGRAA---RPGRAC 463
P PA P G + P P ++T ++PGRA+ RPG
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAP------PAKNTSPGPVSSPGRASGTTRPGPLG 130
Query: 464 SAA--CSEEEDEEDDEEEEDAEDSAGSPGGR----GTGPSAPRDA 502
S EE + E + SA S G R G P P A
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Score = 33.5 bits (75), Expect = 0.83
Identities = 37/137 (27%), Positives = 47/137 (34%), Gaps = 22/137 (16%)
Query: 304 ASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGS 363
A P PP P R P+ GPD + S + S P+ DS EG
Sbjct: 606 ALAPGPPPPPSRSPSSTLSGPDLAG--HSSSATSTPEELRGYDSG-----------PEGG 652
Query: 364 SPIRCPGQCLSPAPRP------PGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP 417
+ P A P P P++ G P A GPG + + T+
Sbjct: 653 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT-GPGSAD--GLCTIYET 709
Query: 418 PPPAPAAPRPGPAQPGP 434
P A P PG PGP
Sbjct: 710 EGPESATPAPGALDPGP 726
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 53.5 bits (127), Expect = 8e-07
Identities = 111/439 (25%), Positives = 149/439 (33%), Gaps = 89/439 (20%)
Query: 82 EMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTL 141
E+ + +EE+ EE+E+ + +E G+PG P P + KHR
Sbjct: 902 EISEASEEKRPRPSTPAEEDEDDPEQEKEAGEPGRPGTKP-PKRDEERGKTQGKHR---- 956
Query: 142 RLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTGPGGAQSPVR 201
+ AL S EA +E D
Sbjct: 957 -------------------------KSFALDSEGEEASQESSSEKDEEDDEEDEEDEDRE 991
Query: 202 PGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGG 261
D E G SD + L + S G S+ SS S S +
Sbjct: 992 EAVD---TTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSS-- 1046
Query: 262 ARLGRMISSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASEPE---PPRE---PPR 315
SS SSSS S + EE PA+ P PPRE P
Sbjct: 1047 -----------------SSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTP 1089
Query: 316 RPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCL-- 373
P +PV E +GS P L E SP + S S+P+R P
Sbjct: 1090 APVEVPV------PERVAGSPVTP-LPEQEASPARPAGPTEE--SPPSAPLRPPEPPAGP 1140
Query: 374 -SPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAP-PPPA--PAAPRPGP 429
+PAPRP P SP P V +E + AP PPPA P A PGP
Sbjct: 1141 PAPAPRPDERPSSPI------PLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGP 1194
Query: 430 AQ----PGPCLFLSNPTRDTITPLWAAPGRAARPGRACSAA---CSEEEDEEDDEEEEDA 482
A G + N D + + + P +R GR+ + +EEE+ E E + A
Sbjct: 1195 ASRKAPRGVERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLA 1254
Query: 483 --EDSAGSPGGRGTGPSAP 499
D A +P RG P+ P
Sbjct: 1255 VLADLALTPARRGL-PALP 1272
Score = 50.1 bits (118), Expect = 9e-06
Identities = 117/478 (24%), Positives = 171/478 (35%), Gaps = 119/478 (24%)
Query: 75 QDDFQEFEMIDDNEEEDDEDEEE-----EEEEEEGDGEGQEGGDPGSE----APAPGPLI 125
Q+ E + DD E+E+DED EE ++E E DGE +E D S+ A + G
Sbjct: 970 QESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEE-SDSSSKCSLYADSDGEND 1028
Query: 126 PSPSVEEPHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGP 185
+ E ++ ++ + S +++ + AL S +P RE+P P
Sbjct: 1029 STSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPP-REVPVP 1087
Query: 186 LPA--------------TDTGPGGAQSPVRPGCDCEGN------RPAEPPA-PGGTSPSS 224
PA P SP RP E + RP EPPA P +P
Sbjct: 1088 TPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRP 1147
Query: 225 D-------PGIEADLRSRSSGGRG------------GRRSSQELSSPGSDSEDAGGARLG 265
D P + + R + + P S G R
Sbjct: 1148 DERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTI 1207
Query: 266 RMI----SSISETELELSSDGGSSSSGRSSHLTNSIEEASSPASE------PEPPREPPR 315
R + +S+ ++ E S GG S +G LT EE + P +E + P R
Sbjct: 1208 RNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTE--EEEAEPGTEVDLAVLADLALTPAR 1265
Query: 316 RPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSP 375
R LP P +SE + S++A+ P L+S ++ E + + +P
Sbjct: 1266 RG--LPALPAVEDSE-------ATETSDEAERP---RPLLSHILLEHNYALAVKPTPPAP 1313
Query: 376 APRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETLCAPPPPAPAAPRPGPAQPGPC 435
A RPP EPV PA A S E P E+V E A P P Q
Sbjct: 1314 ALRPP-EPV-PAPAALFSSPADEVLEAP---EVVVAE-----------AEEPKPQQ---- 1353
Query: 436 LFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRG 493
L + EE +EE +EEEE++ DS+ S G G
Sbjct: 1354 --LQQQREEG----------------------EEEGEEEGEEEEEESSDSSSSSDGEG 1387
Score = 48.9 bits (115), Expect = 2e-05
Identities = 98/457 (21%), Positives = 152/457 (33%), Gaps = 97/457 (21%)
Query: 25 QDISLEEFDDEDLSEITDDCGLGLSYDSDHCEKDSLSLGRSEQPHPICSFQDDFQEFEMI 84
++ + + +DE+ S+ + C L Y E DS S S S
Sbjct: 999 KETEVSDGEDEE-SDSSSKCSL---YADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSS 1054
Query: 85 DDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPTTLRLT 144
+ E EDEEEEE P E P P P VE P R +T
Sbjct: 1055 SSSSESSSEDEEEEERP----AALPSASPPPREVPVPTPA----PVEVPVPERVAGSPVT 1106
Query: 145 TLGAQDSLNNNGGFDLVRPAS-WQETALCSPA--PEALRELPGPLPATDTGPGGAQSPVR 201
L Q++ RPA +E+ +P PE P P P D P +
Sbjct: 1107 PLPEQEA-------SPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLP 1159
Query: 202 PG--------------CDCEGNRPAEPPA---PGGTSPSSDPGIEADLRS---------- 234
P PA PP PG S + G+E +R+
Sbjct: 1160 PPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRGVERTIRNLPLDHASLVK 1219
Query: 235 ----------RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRM--------ISSISETEL 276
RS G GR + +E + PG++ + A A L + ++ ++E
Sbjct: 1220 SWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALTPARRGLPALPAVEDSEA 1279
Query: 277 ELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSE 336
+SD SH+ +E + A +P PP R P +P +S + E
Sbjct: 1280 TETSDEAERPRPLLSHIL--LEHNYALAVKPTPPAPALRPPEPVPAPAALFSSPADEVLE 1337
Query: 337 SEPDLSEDADSPWLLSNLVSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQD 396
+ + +A+ P P + Q R GE G ++ +
Sbjct: 1338 APEVVVAEAEEP---------------KPQQLQQQ------REEGEEEGEEEGEEEEEES 1376
Query: 397 PEAAAGPGGVELVDMETLCA-------PPPPAPAAPR 426
++++ G + +L + PPPP P PR
Sbjct: 1377 SDSSSSSDGEGALRRRSLRSHARRRRPPPPPPPPPPR 1413
Score = 43.5 bits (101), Expect = 8e-04
Identities = 77/348 (22%), Positives = 122/348 (35%), Gaps = 41/348 (11%)
Query: 185 PLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRR 244
P T G G +P +R P + G +P S G R + +
Sbjct: 228 PAGTTAVGTPGNGTPCSQDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAY 287
Query: 245 SSQELSSP------GSDSEDAGGAR--LGRMISSISETELELSSDGGSSSSGRSSHLTNS 296
SS S+ + +DA R S+ + T + ++ +SSS SS L++S
Sbjct: 288 SSSTTSTSFKPRRSENSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSS 347
Query: 297 IEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPW--LLSNL 354
+SS +S + PA+ ++ + Y+ + P + + P N
Sbjct: 348 -SSSSSSSSSSQFRSSDANYPAYY-----ESWNRYQRHTSYPPRRATREEPPGAPFAENT 401
Query: 355 VSRMISEGSS-----PIRCPGQCLSP--APRPPGEPVSPAGGAAQDSQDPEAAAGPGGVE 407
R +S P R Q P + PP EP P GG PE
Sbjct: 402 AERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGGPSPERE------- 454
Query: 408 LVDMETLCAPPPPAPA-APRPGPAQPGPCL-FLSNPTRDTITPLWAAPGRAARPGRACSA 465
E +P P +PA + P P + F + + D+ + R+ +
Sbjct: 455 ----EVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDSRIEMLLKEQRS----KFSFL 506
Query: 466 ACSEEEDEEDDEEEEDAEDSAGS-PGGRGTGPSAPRDASLVYDAVKYT 512
A EE+EE+ A D+ P G G GP P A ++ V T
Sbjct: 507 ASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFEDVAPT 554
Score = 42.7 bits (99), Expect = 0.001
Identities = 61/260 (23%), Positives = 84/260 (32%), Gaps = 43/260 (16%)
Query: 181 ELPGPLPATDTGPGGAQSPVRPGCDCEGN-RPAEP-----PAPGGTSPSSDPGIEADLRS 234
E P P P G GG P + + RPA P PAP T+ S + L S
Sbjct: 431 EAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPFAQHSSLDS 490
Query: 235 RSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSSSGRSSHLT 294
R +RS + ++ E+ + M+ +T E+ S G
Sbjct: 491 RIEMLLKEQRSKFSFLASDTEEEEENSS----MVLGARDTGSEVPSGSGHGPCTPPPAPA 546
Query: 295 NSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPWLLSNL 354
N + A + + EP RE P+ + N S + ++S+D
Sbjct: 547 NFEDVAPTGSGEPGATRESPKA--------NGQNQASPCSSGDDMEISDD---------- 588
Query: 355 VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEAAAGPGGVELVDMETL 414
G SP P P P PP P P P A+ P G L
Sbjct: 589 -----DRGGSPPPAPTPPQQPPPPPPPPPPPP----------PYLASLPLGYPPHQPAYL 633
Query: 415 CAPPPPAPAAPRPGPAQPGP 434
P P P P P P P
Sbjct: 634 LPPRPDGPPPPEYPPPPPPP 653
Score = 35.8 bits (81), Expect = 0.17
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 19/89 (21%)
Query: 56 EKDSLSLGRSEQPHPICSFQDDFQEFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPG 115
E + + +E+P P Q+ + + EE+ E+E EEEEEE D G+
Sbjct: 1337 EAPEVVVAEAEEPKP--------QQLQQQREEGEEEGEEEGEEEEEESSDSSSSSDGEGA 1388
Query: 116 -----------SEAPAPGPLIPSPSVEEP 133
P P P P P EP
Sbjct: 1389 LRRRSLRSHARRRRPPPPPPPPPPRAYEP 1417
Score = 35.4 bits (80), Expect = 0.22
Identities = 46/178 (25%), Positives = 61/178 (34%), Gaps = 44/178 (24%)
Query: 460 GRACSAACSEEEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHT 519
G S S E+DEEDDEE+E+ ED V K T V D
Sbjct: 965 GEEASQESSSEKDEEDDEEDEEDEDR----------------EEAVDTTKKETEVSD--- 1005
Query: 520 QLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDSPDLTFSKKFLNV 579
G D E DS + S L D++ DS + S
Sbjct: 1006 -------------GEDEESDSSSKCS-------LYADSDGENDSTSDSESSSSSSS---- 1041
Query: 580 FVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVEAEE 637
+S+S SSS+ S S + +E E+ A P E+ + PV V E
Sbjct: 1042 -SSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPE 1098
Score = 33.9 bits (76), Expect = 0.63
Identities = 53/228 (23%), Positives = 76/228 (33%), Gaps = 47/228 (20%)
Query: 109 QEGGDPGSEAPAPGPLIP---------SPSVEEPHKH-RPTTLRLTTLGAQDSLNNNGGF 158
Q+ P SEAP P P P SP EE RP + + A ++ N + F
Sbjct: 423 QDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVPF 482
Query: 159 DLVRPASWQETALCSPAPEALRELPGPLP--ATDTGPGGAQSPVRPGCDCEGNRPAEPPA 216
Q ++L S L+E A+DT S + G G+
Sbjct: 483 A-------QHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSG 535
Query: 217 PGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETEL 276
G +P P D+ SG G R S + + S + G ++
Sbjct: 536 HGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSG------------DDM 583
Query: 277 ELSSDGGSSSSGRSSHLTNSIEEASSPASEPEPPREPPRRPAFLPVGP 324
E+S D + SP P PP++PP P P P
Sbjct: 584 EISDD----------------DRGGSPPPAPTPPQQPPPPPPPPPPPP 615
Score = 32.0 bits (71), Expect = 2.4
Identities = 43/180 (23%), Positives = 65/180 (36%), Gaps = 20/180 (11%)
Query: 470 EEDEEDDEEEEDAEDSAGSPGGRGTGPSAPRDASLVYDAVKYTLVVDEHTQLELVSLRRC 529
EEDE+D E+E++A G PG GT P RD K+ ++ E S
Sbjct: 919 EEDEDDPEQEKEA----GEPGRPGTKP-PKRDEERGKTQGKHRKSFALDSEGEEASQESS 973
Query: 530 AGLGHDSEEDSGGEASEEEAGAALLGGGQVSGDTSPDSP---------------DLTFSK 574
+ + +E+ + EEA +VS +S D T
Sbjct: 974 SEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDS 1033
Query: 575 KFLNVFVNSTSRSSSTESFGLFSCLVNGEEREQTHRAVFRFIPRHPDELELDVDDPVLVE 634
+ + +S+S SSS+ S S + E E+ P E+ V P VE
Sbjct: 1034 ESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAALPSASPPPREVPVPTPAPVE 1093
>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
Length = 2365
Score = 53.5 bits (127), Expect = 8e-07
Identities = 80/352 (22%), Positives = 130/352 (36%), Gaps = 81/352 (23%)
Query: 167 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 226
Q+ L SP P A+ ++ G G Q PV P C+ ++PA P
Sbjct: 134 QKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPA---------PHQQS 184
Query: 227 GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSS 286
+A+++SR G + +S+ GS+++ GG+ +++
Sbjct: 185 KAQAEMQSRLPG------PTARVSAAGSEAKTRGGS---------------------TTA 217
Query: 287 SGRSSHLTNSIEEASSPASEPEPPREPPRRP-----AFLPVGPDDTNSEYESGSESEPDL 341
+ R S N+ +++ S P PP + P + P D+ + ESGS S P
Sbjct: 218 NNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTN 277
Query: 342 SED---------ADSPWLLSNL-VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAA 391
A PW +L V + ++ PG APRP E + PA
Sbjct: 278 CSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPG---PEAPRPTPEAMKPAPNNQ 334
Query: 392 QDSQD----------PEAAAGPGG--VELVDMETLCA--PPPPAPAAPR----PGPAQPG 433
+ + +A GPG +ETL + AA R GPA
Sbjct: 335 KSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSS 394
Query: 434 PCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDS 485
P + L + T + RA + S+ E+++E + E+D E S
Sbjct: 395 PKIALKGIAQRTFS-------RALTNKK--SSLKGNEKEKEKQQREKDKEKS 437
>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
Length = 2432
Score = 53.5 bits (127), Expect = 8e-07
Identities = 80/352 (22%), Positives = 130/352 (36%), Gaps = 81/352 (23%)
Query: 167 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 226
Q+ L SP P A+ ++ G G Q PV P C+ ++PA P
Sbjct: 198 QKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPA---------PHQQS 248
Query: 227 GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSS 286
+A+++SR G + +S+ GS+++ GG+ +++
Sbjct: 249 KAQAEMQSRLPG------PTARVSAAGSEAKTRGGS---------------------TTA 281
Query: 287 SGRSSHLTNSIEEASSPASEPEPPREPPRRP-----AFLPVGPDDTNSEYESGSESEPDL 341
+ R S N+ +++ S P PP + P + P D+ + ESGS S P
Sbjct: 282 NNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTN 341
Query: 342 SED---------ADSPWLLSNL-VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAA 391
A PW +L V + ++ PG APRP E + PA
Sbjct: 342 CSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPG---PEAPRPTPEAMKPAPNNQ 398
Query: 392 QDSQD----------PEAAAGPGG--VELVDMETLCA--PPPPAPAAPR----PGPAQPG 433
+ + +A GPG +ETL + AA R GPA
Sbjct: 399 KSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSS 458
Query: 434 PCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDS 485
P + L + T + RA + S+ E+++E + E+D E S
Sbjct: 459 PKIALKGIAQRTFS-------RALTNKK--SSLKGNEKEKEKQQREKDKEKS 501
>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
Length = 2429
Score = 53.5 bits (127), Expect = 8e-07
Identities = 80/352 (22%), Positives = 130/352 (36%), Gaps = 81/352 (23%)
Query: 167 QETALCSPAPEALRELPGPLPATDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDP 226
Q+ L SP P A+ ++ G G Q PV P C+ ++PA P
Sbjct: 198 QKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPA---------PHQQS 248
Query: 227 GIEADLRSRSSGGRGGRRSSQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGSSS 286
+A+++SR G + +S+ GS+++ GG+ +++
Sbjct: 249 KAQAEMQSRLPG------PTARVSAAGSEAKTRGGS---------------------TTA 281
Query: 287 SGRSSHLTNSIEEASSPASEPEPPREPPRRP-----AFLPVGPDDTNSEYESGSESEPDL 341
+ R S N+ +++ S P PP + P + P D+ + ESGS S P
Sbjct: 282 NNRRSQSFNNYDKSKPVTSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTN 341
Query: 342 SED---------ADSPWLLSNL-VSRMISEGSSPIRCPGQCLSPAPRPPGEPVSPAGGAA 391
A PW +L V + ++ PG APRP E + PA
Sbjct: 342 CSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPG---PEAPRPTPEAMKPAPNNQ 398
Query: 392 QDSQD----------PEAAAGPGG--VELVDMETLCA--PPPPAPAAPR----PGPAQPG 433
+ + +A GPG +ETL + AA R GPA
Sbjct: 399 KSMLEKLKLFNSKGGSKAGEGPGSRDTSCERLETLPSFEESEELEAASRMLTTVGPASSS 458
Query: 434 PCLFLSNPTRDTITPLWAAPGRAARPGRACSAACSEEEDEEDDEEEEDAEDS 485
P + L + T + RA + S+ E+++E + E+D E S
Sbjct: 459 PKIALKGIAQRTFS-------RALTNKK--SSLKGNEKEKEKQQREKDKEKS 501
>gi|116089331 human immunodeficiency virus type I enhancer binding
protein 3 [Homo sapiens]
Length = 2406
Score = 53.5 bits (127), Expect = 8e-07
Identities = 47/154 (30%), Positives = 67/154 (43%), Gaps = 31/154 (20%)
Query: 80 EFEMIDDNEEEDDEDEEEEEEEEEGDGEGQEGGDPGSEAPAPGPLIPSPSVEEPHKHRPT 139
+F ++D++ + D DE+E+E+EEE E P SEAP PGP PH R
Sbjct: 1846 QFSDLEDSDSDSDLDEDEDEDEEESQDELSR---PSSEAPPPGP---------PHALRAD 1893
Query: 140 TLRLTTLGAQDSLNNNGGFDLVRPASWQE-----TALCSPAPEALRELP--GPLP----A 188
+ + LG Q G + R +S E + CS + +++ LP GP P
Sbjct: 1894 SSPI--LGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVE 1951
Query: 189 TDTGPGGAQSPVRPGCDCEGNRPAEPPAPGGTSP 222
DTG + PV P RP P G+ P
Sbjct: 1952 KDTGSALSYKPVSP------RRPWSPSKEAGSRP 1979
Score = 41.6 bits (96), Expect = 0.003
Identities = 82/337 (24%), Positives = 114/337 (33%), Gaps = 49/337 (14%)
Query: 98 EEEEEEGDGEGQEGGD-PGSEAPAPGPLIPSPSVEEPHKHRPTTLRLTTLGAQDSLNNNG 156
E+ + G EG D P ++ P+P P +P H +P +R + + L
Sbjct: 807 EKSDSLEQPSGLEGEDKPLAQFPSPPP---APHGRSAHSLQPKLVRQPNIQVPEILVTE- 862
Query: 157 GFDLVRPASWQETALCSPAPEALRELPGP--------LPATDTGPGGAQSPVRPGCDCEG 208
+ RP + E PE E P LPA P + + G
Sbjct: 863 --EPDRPDTEPEPP--PKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSG 918
Query: 209 NRPAEPPAPGGTSPSSDPGIEADLRSRSSGGRGGRRSSQELSSPGSD--SEDAGGARLGR 266
E P SPS + + SRS+ E SP SD + G L
Sbjct: 919 ESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTV 978
Query: 267 MISSISETELELSSDGGSSSSGRSSHLTN-----------SIEEASSPASEPEPPR--EP 313
E+ S+ S + S+H+T S+ S+PA P R P
Sbjct: 979 PSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPP 1038
Query: 314 PRRPAFLPVGPDDTNSEYESGSESEPDLSEDADSPW----------LLSNLVSRMISEGS 363
RR FL V + ES E P ++++ P LS + S S G
Sbjct: 1039 ERRKCFL-VRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGG 1097
Query: 364 SP-IRCPGQCLSPAPRPPGEPVSPAGGAAQDSQDPEA 399
P + PGQ RPP P P A Q P A
Sbjct: 1098 PPGGKGPGQ-----DRPPLGPTVPYTEALQVFHHPVA 1129
>gi|166795264 AE binding protein 2 isoform b [Homo sapiens]
Length = 517
Score = 52.8 bits (125), Expect = 1e-06
Identities = 61/231 (26%), Positives = 98/231 (42%), Gaps = 37/231 (16%)
Query: 88 EEEDDEDEEEEEEEEE------------GDGEGQEGGDPGSEAPA---PGPLIPSPSVEE 132
EEE++E+EEEEE E E G G G GG G EA P P S + E+
Sbjct: 37 EEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGED 96
Query: 133 PHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTG 192
+ +D +++GG + A + + + R L ++ +G
Sbjct: 97 EDEEEDDE------EEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSG 150
Query: 193 PGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG-----RGGRRSSQ 247
G + + + +G R ++ GG+S SS D + GG GGRR S
Sbjct: 151 DGDGKEGLE---EPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSL 207
Query: 248 ELSSPGS-----DSEDAGGARLGRMISSIS---ETELELSSDGGSSSSGRS 290
E+SS G DSED+ + + + S+IS T ++ G ++SS ++
Sbjct: 208 EMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKN 258
Score = 38.1 bits (87), Expect = 0.034
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 25/113 (22%)
Query: 452 APGRAARPGRACSAACSEEEDEEDDEEEEDAEDSA------GSPGGRGTGPSAPRDASLV 505
+PG AAR GRA EEE+EE++EEE +AE A GS GG G G
Sbjct: 24 SPGSAAR-GRA--EPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG--- 77
Query: 506 YDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQ 558
E + S + G D +E+ E E+E+ ++ GGG+
Sbjct: 78 -----------EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSS--GGGE 117
Score = 30.4 bits (67), Expect = 7.0
Identities = 42/172 (24%), Positives = 58/172 (33%), Gaps = 26/172 (15%)
Query: 198 SPVRPGCDCEGNRP-AEPPAPGGTSPSSDPGIEAD------LRSRSSGGRGGRRS----- 245
SP+ PG R AEPP + EA+ L S GG GG
Sbjct: 18 SPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
Query: 246 -SQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGS----------SSSGRSSHLT 294
++ +S P +S G E + SS GG SS G SS T
Sbjct: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDET 137
Query: 295 NSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDAD 346
S+ ++ +S + + P GP + GS S +S D
Sbjct: 138 RSLSPGAASSSSGDGDGKEGLEE---PKGPRGSQGGGGGGSSSSSVVSSGGD 186
>gi|166795262 AE binding protein 2 isoform a [Homo sapiens]
Length = 503
Score = 52.8 bits (125), Expect = 1e-06
Identities = 61/231 (26%), Positives = 98/231 (42%), Gaps = 37/231 (16%)
Query: 88 EEEDDEDEEEEEEEEE------------GDGEGQEGGDPGSEAPA---PGPLIPSPSVEE 132
EEE++E+EEEEE E E G G G GG G EA P P S + E+
Sbjct: 37 EEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGGEAETMSEPSPESASQAGED 96
Query: 133 PHKHRPTTLRLTTLGAQDSLNNNGGFDLVRPASWQETALCSPAPEALRELPGPLPATDTG 192
+ +D +++GG + A + + + R L ++ +G
Sbjct: 97 EDEEEDDE------EEEDESSSSGGGEEESSAESLVGSSGGSSSDETRSLSPGAASSSSG 150
Query: 193 PGGAQSPVRPGCDCEGNRPAEPPAPGGTSPSSDPGIEADLRSRSSGG-----RGGRRSSQ 247
G + + + +G R ++ GG+S SS D + GG GGRR S
Sbjct: 151 DGDGKEGLE---EPKGPRGSQGGGGGGSSSSSVVSSGGDEGYGTGGGGSSATSGGRRGSL 207
Query: 248 ELSSPGS-----DSEDAGGARLGRMISSIS---ETELELSSDGGSSSSGRS 290
E+SS G DSED+ + + + S+IS T ++ G ++SS ++
Sbjct: 208 EMSSDGEPLSRMDSEDSISSTIMDVDSTISSGRSTPAMMNGQGSTTSSSKN 258
Score = 38.1 bits (87), Expect = 0.034
Identities = 36/113 (31%), Positives = 50/113 (44%), Gaps = 25/113 (22%)
Query: 452 APGRAARPGRACSAACSEEEDEEDDEEEEDAEDSA------GSPGGRGTGPSAPRDASLV 505
+PG AAR GRA EEE+EE++EEE +AE A GS GG G G
Sbjct: 24 SPGSAAR-GRA--EPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG--- 77
Query: 506 YDAVKYTLVVDEHTQLELVSLRRCAGLGHDSEEDSGGEASEEEAGAALLGGGQ 558
E + S + G D +E+ E E+E+ ++ GGG+
Sbjct: 78 -----------EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSS--GGGE 117
Score = 30.4 bits (67), Expect = 7.0
Identities = 42/172 (24%), Positives = 58/172 (33%), Gaps = 26/172 (15%)
Query: 198 SPVRPGCDCEGNRP-AEPPAPGGTSPSSDPGIEAD------LRSRSSGGRGGRRS----- 245
SP+ PG R AEPP + EA+ L S GG GG
Sbjct: 18 SPLPPGSPGSAARGRAEPPEEEEEEEEEEEEAEAEAVAALLLNGGSGGGGGGGGGGVGGG 77
Query: 246 -SQELSSPGSDSEDAGGARLGRMISSISETELELSSDGGS----------SSSGRSSHLT 294
++ +S P +S G E + SS GG SS G SS T
Sbjct: 78 EAETMSEPSPESASQAGEDEDEEEDDEEEEDESSSSGGGEEESSAESLVGSSGGSSSDET 137
Query: 295 NSIEEASSPASEPEPPREPPRRPAFLPVGPDDTNSEYESGSESEPDLSEDAD 346
S+ ++ +S + + P GP + GS S +S D
Sbjct: 138 RSLSPGAASSSSGDGDGKEGLEE---PKGPRGSQGGGGGGSSSSSVVSSGGD 186
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.133 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,274,588
Number of Sequences: 37866
Number of extensions: 3059973
Number of successful extensions: 56954
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 740
Number of HSP's successfully gapped in prelim test: 1699
Number of HSP's that attempted gapping in prelim test: 23974
Number of HSP's gapped (non-prelim): 21390
length of query: 824
length of database: 18,247,518
effective HSP length: 111
effective length of query: 713
effective length of database: 14,044,392
effective search space: 10013651496
effective search space used: 10013651496
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.