BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|6912326 family with sequence similarity 50, member B [Homo sapiens] (325 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|6912326 family with sequence similarity 50, member B [Homo sa... 648 0.0 gi|4758220 XAP-5 protein [Homo sapiens] 518 e-147 gi|148746195 trichohyalin [Homo sapiens] 57 3e-08 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 56 5e-08 gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 52 7e-07 gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 52 7e-07 gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 52 7e-07 gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 52 7e-07 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 52 7e-07 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 51 1e-06 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 50 3e-06 gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 49 5e-06 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 49 6e-06 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 49 6e-06 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 49 6e-06 gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 49 6e-06 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 49 6e-06 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 49 8e-06 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 1e-05 gi|109150435 ankyrin repeat and zinc finger domain containing 1 ... 48 1e-05 gi|109150425 ankyrin repeat and zinc finger domain containing 1 ... 48 1e-05 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 48 1e-05 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 48 1e-05 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 47 2e-05 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 47 2e-05 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 47 2e-05 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 47 2e-05 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 47 3e-05 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 47 3e-05 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 47 3e-05 >gi|6912326 family with sequence similarity 50, member B [Homo sapiens] Length = 325 Score = 648 bits (1672), Expect = 0.0 Identities = 325/325 (100%), Positives = 325/325 (100%) Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL Sbjct: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60 Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL Sbjct: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120 Query: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV 180 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV Sbjct: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKV 180 Query: 181 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE 240 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE Sbjct: 181 KDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKE 240 Query: 241 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK 300 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK Sbjct: 241 DLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDESHAGKVVLRSWYEK 300 Query: 301 NKHIFPASRWEAYDPEKKWDKYTIR 325 NKHIFPASRWEAYDPEKKWDKYTIR Sbjct: 301 NKHIFPASRWEAYDPEKKWDKYTIR 325 >gi|4758220 XAP-5 protein [Homo sapiens] Length = 339 Score = 518 bits (1334), Expect = e-147 Identities = 252/339 (74%), Positives = 296/339 (87%), Gaps = 14/339 (4%) Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60 MAQYKG EAGRAMHL+KKRE+QREQME +KQRIAEE I+KS +DK+FSAHYDAVEAEL Sbjct: 1 MAQYKGAASEAGRAMHLMKKREKQREQMEQMKQRIAEENIMKSNIDKKFSAHYDAVEAEL 60 Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120 KSSTVGLVTLNDMKA+QEALV+ERE+QLAK++ +E +++ E+ RE+E+++E KRKIS L Sbjct: 61 KSSTVGLVTLNDMKAKQEALVKEREKQLAKKEQSKELQMKLEKLREKERKKEAKRKISSL 120 Query: 121 SFALDDLDDQADAAE--------------ARRAGNLGKNPDVDTSFLPDRDREEEENRLR 166 SF L++ ++ + E + LGKNPDVDTSFLPDRDREEEENRLR Sbjct: 121 SFTLEEEEEGGEEEEEAAMYEEEMEREEITTKKRKLGKNPDVDTSFLPDRDREEEENRLR 180 Query: 167 EELRQEWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLE 226 EELRQEWEA++EK+K EE+E+TFSYWDGSGHRRTV++RKGNT+QQFL+KAL+ LRKDF E Sbjct: 181 EELRQEWEAKQEKIKSEEIEITFSYWDGSGHRRTVKMRKGNTMQQFLQKALEILRKDFSE 240 Query: 227 LRSAGVEQLMFIKEDLILPHYHTFYDFIIARARGKSGPLFSFDVHDDVRLLSDATMEKDE 286 LRSAGVEQLM+IKEDLI+PH+H+FYDFI+ +ARGKSGPLF+FDVHDDVRLLSDAT+EKDE Sbjct: 241 LRSAGVEQLMYIKEDLIIPHHHSFYDFIVTKARGKSGPLFNFDVHDDVRLLSDATVEKDE 300 Query: 287 SHAGKVVLRSWYEKNKHIFPASRWEAYDPEKKWDKYTIR 325 SHAGKVVLRSWYEKNKHIFPASRWE YDPEKKWDKYTIR Sbjct: 301 SHAGKVVLRSWYEKNKHIFPASRWEPYDPEKKWDKYTIR 339 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 56.6 bits (135), Expect = 3e-08 Identities = 59/219 (26%), Positives = 95/219 (43%), Gaps = 36/219 (16%) Query: 13 RAMHLLKKRERQR------EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVG 66 R LLK+ E +R EQ E L+QR+ E + + + ++R E E + Sbjct: 574 RRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQL 633 Query: 67 LVTLNDMKARQEALVRERE----------------RQLAKRQHLEEQRLQQERQREQEQR 110 L + + RQ+ L RE++ Q KR+H EE+R Q+ + EQEQ Sbjct: 634 LKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA 693 Query: 111 RER-KRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREEL 169 RER K +I + L+ +ADA +++ K R +E+EE R R E Sbjct: 694 RERIKSRIPKWQW---QLESEADARQSKVYSRPRKQEG------QRRRQEQEEKRRRRES 744 Query: 170 RQEW---EAQREKVKDEEMEVTFSYWDGSGHRRTVRVRK 205 +W E + ++EE F+ W ++ R R+ Sbjct: 745 ELQWQEEERAHRQQQEEEQRRDFT-WQWQAEEKSERGRQ 782 Score = 55.8 bits (133), Expect = 5e-08 Identities = 54/189 (28%), Positives = 89/189 (47%), Gaps = 20/189 (10%) Query: 8 MREAGRAMHLLKKRERQRE--QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65 +R GR ++RERQ Q E K+ ET+L+ + +K + EL+ Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEK-LQEEEPQRQRELQEEEE 276 Query: 66 GLVTLNDMKARQEALVRE-------RERQLAKRQHLEEQRLQQERQREQEQRRERKRKIS 118 L L + R+E E RE+QL ++Q EE+R QQE +REQ++RRE++ + Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQE-EERREQQEERREQQERREQQEERR 335 Query: 119 CLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQRE 178 + E RR L + + + R RE+EE R ++LR+E + +RE Sbjct: 336 EQQLRREQ--------EERREQQLRREQEEERREQQLR-REQEEERREQQLRREQQLRRE 386 Query: 179 KVKDEEMEV 187 + E ++ Sbjct: 387 QQLRREQQL 395 Score = 51.6 bits (122), Expect = 9e-07 Identities = 49/177 (27%), Positives = 82/177 (46%), Gaps = 33/177 (18%) Query: 13 RAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLND 72 R LLK+ E +R + E +QR+ E Q ++R + LK + Sbjct: 545 RREQLLKREEEKRLEQERREQRLKRE-----QEERR--------DQLLK---------RE 582 Query: 73 MKARQEALVRERERQLAKRQHLEE-QRLQQERQREQEQRRERKRKISCLSFALDDLDDQA 131 + RQ+ L RE+E +L +R EE +RL+QE +REQ +RE + + ++ Sbjct: 583 EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEER 642 Query: 132 DAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR--EKVKDEEME 186 + RR + + REEEE RL + L++E E +R +++ +EE E Sbjct: 643 RQQQLRREQQERREQRL--------KREEEEERLEQRLKREHEEERREQELAEEEQE 691 Score = 51.2 bits (121), Expect = 1e-06 Identities = 45/180 (25%), Positives = 87/180 (48%), Gaps = 17/180 (9%) Query: 13 RAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLND 72 R L++RERQ + E L+Q EE +L + + R +E + + + Sbjct: 1038 REKRRLQERERQYREEEELQQE--EEQLLGEERETR---RRQELERQYRKE-------EE 1085 Query: 73 MKARQEALVRE----RERQLAKRQHLEEQRLQQ-ERQREQEQRRERKRKISCLSFALDDL 127 ++ +E L+RE R RQ +RQ EE+ LQQ E Q +E+R +R+R+ + ++ Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145 Query: 128 DDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEV 187 Q + R + +++ + + + ++EE +L E +++ +RE+ EE E+ Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL 1205 Score = 50.4 bits (119), Expect = 2e-06 Identities = 52/218 (23%), Positives = 101/218 (46%), Gaps = 23/218 (10%) Query: 23 RQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALVR 82 RQR++ + ++R AEE L+S D + + L+ L K R+E + Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRE----LLELR-RKGREEKQQQ 229 Query: 83 ERERQ-----------LAKRQHL---EEQRLQQE---RQREQEQRRERKRKISCLSFALD 125 RERQ KR+ + EE++LQ+E RQRE ++ E+ RK+ + Sbjct: 230 RRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289 Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEM 185 +++ RR L + + + + RE++E R ++E R+E + +RE+ + E Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQ 349 Query: 186 EVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKD 223 ++ + ++ R ++ +Q L++ Q LR++ Sbjct: 350 QLRREQEEERREQQLRREQEEERREQQLRRE-QQLRRE 386 Score = 50.1 bits (118), Expect = 3e-06 Identities = 45/169 (26%), Positives = 84/169 (49%), Gaps = 20/169 (11%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 ++R +++E+ E L+QR+ E L+ + ++R E + + + R++ Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL----------EQERREQ 565 Query: 79 ALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARR 138 L RE+E + + EE+R QQ +REQE+R E++ K ++ L+ E RR Sbjct: 566 RLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKRE----EVERLEQ-----EERR 616 Query: 139 AGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQRE-KVKDEEME 186 L + + EE+E R +++LR+E + +RE ++K EE E Sbjct: 617 EQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665 Score = 49.7 bits (117), Expect = 4e-06 Identities = 44/197 (22%), Positives = 87/197 (44%), Gaps = 28/197 (14%) Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAV----------- 56 +R R L R+R+ + E L Q E+ + + + D++F + Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQ 1711 Query: 57 -EAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115 E +L+ + + + RQE + RQ R+ LEE++L+ ER+ +Q +R+ER R Sbjct: 1712 EEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771 Query: 116 KISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRD--REEEENRLREELRQ-- 171 K ++ + R L ++ + D F + +E EE +LR + R Sbjct: 1772 KFR----------EEEQLRQEREEQQL-RSQESDRKFREEEQLRQEREEQQLRPQQRDGK 1820 Query: 172 -EWEAQREKVKDEEMEV 187 WE ++ +++++E + Sbjct: 1821 YRWEEEQLQLEEQEQRL 1837 Score = 49.3 bits (116), Expect = 5e-06 Identities = 59/246 (23%), Positives = 112/246 (45%), Gaps = 22/246 (8%) Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDA---VEAELK 61 KG E R + + R+RQ +Q L+ + E+ + ++R D E +L+ Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQD--LQHLLGEQQERDREQERRRWQQRDRHFPEEEQLE 1300 Query: 62 SSTVGLVTLNDMKARQEA-LVRE-----RERQLAKRQHLEEQRLQQERQREQEQRRERKR 115 D K+++E L+RE R RQ R+ EE++L QER+ + +R+ER R Sbjct: 1301 REEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDR 1360 Query: 116 KISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEA 175 K F ++L Q + + + + FL +EE++ R +E +Q + Sbjct: 1361 K-----FREEELRHQEQGRKFLEEEQRLRRQERERKFL----KEEQQLRCQEREQQLRQD 1411 Query: 176 QREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235 + K ++EE +++ D +VR+ ++FL++ Q ++ + R EQL Sbjct: 1412 RDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE--EQL 1469 Query: 236 MFIKED 241 + +E+ Sbjct: 1470 LQEREE 1475 Score = 48.9 bits (115), Expect = 6e-06 Identities = 41/172 (23%), Positives = 81/172 (47%), Gaps = 15/172 (8%) Query: 13 RAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLND 72 R L ++++ +REQ +Q++ E L+ + R + E + + + Sbjct: 391 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKRE 450 Query: 73 MKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQAD 132 + R++ L RE E + +H +E+R QQ ++ ++E+RRER K+ +++ Sbjct: 451 QEERRDWLKREEETE----RHEQERRKQQLKRDQEEERRERWLKLE---------EEERR 497 Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184 + RR L + + R+EEE RL++ LR E + +RE+ + E Sbjct: 498 EQQERREQQLRREQEERRE--QRLKRQEEEERLQQRLRSEQQLRREQEERRE 547 Score = 48.9 bits (115), Expect = 6e-06 Identities = 59/237 (24%), Positives = 101/237 (42%), Gaps = 44/237 (18%) Query: 3 QYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKS 62 Q + +R R + R+R+ + E L+Q E+ + + + D++F V + + Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594 Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSF 122 + D + + +++ RQ R+ E+++L QER+ +Q R+ER RK Sbjct: 1595 RKF----MEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKF----- 1645 Query: 123 ALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE--EEENRLREELRQEWEAQR--E 178 L+++ R L DRDR+ EEE L+E Q+ Q Sbjct: 1646 ----LEEEPQLRRQEREQQLRH----------DRDRKFREEEQLLQEGEEQQLRRQERDR 1691 Query: 179 KVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235 K ++EE ++ RR R RK FL++ Q LR+ LE + EQL Sbjct: 1692 KFREEEQQL----------RRQERERK------FLQEE-QQLRRQELERKFREEEQL 1731 Score = 45.8 bits (107), Expect = 5e-05 Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 20/170 (11%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKAR-- 76 +K+E QR + E ++R E+ L+ Q ++R AH E E + + R Sbjct: 724 RKQEGQRRRQEQEEKRRRRESELQWQEEER--AHRQQQEEEQRRDFTWQWQAEEKSERGR 781 Query: 77 -----QEALVRERERQLA--KRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 + L +RERQL +RQ E++ L +E ++EQ +R+ R+R+ L L++ Sbjct: 782 QRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE-----LQFLEE 836 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179 + RA L + D D++R + + R++ + W+ + E+ Sbjct: 837 EEQLQRRERAQQLQEEED---GLQEDQERRRSQEQRRDQ-KWRWQLEEER 882 Score = 45.8 bits (107), Expect = 5e-05 Identities = 44/127 (34%), Positives = 63/127 (49%), Gaps = 23/127 (18%) Query: 73 MKARQEALVRE----RERQLAKRQHLEEQRLQQE------RQREQEQRRERKRKISCLSF 122 ++ +E L RE R RQ +RQ+ EE++LQQE +RE+ +R+ER+R+ Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYR-KDK 964 Query: 123 ALDDLDDQ--ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREE----LRQEWEAQ 176 L ++Q + E RR K + ++EEE LREE RQEWE Q Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEEL-----QQEEEQLLREEREKRRRQEWERQ 1019 Query: 177 REKVKDE 183 K KDE Sbjct: 1020 YRK-KDE 1025 Score = 45.4 bits (106), Expect = 7e-05 Identities = 45/170 (26%), Positives = 79/170 (46%), Gaps = 23/170 (13%) Query: 20 KRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA 79 KRE + E+ E Q ++ + + Q ++R E E + + R++ Sbjct: 459 KREEETERHE---QERRKQQLKRDQEEERRERWLKLEEEERREQ---------QERREQQ 506 Query: 80 LVRERER---QLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEA 136 L RE+E Q KRQ EE+RLQQ + EQ+ RRE++ + L +++ + Sbjct: 507 LRREQEERREQRLKRQE-EEERLQQRLRSEQQLRREQEERRE----QLLKREEEKRLEQE 561 Query: 137 RRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 RR L + + L R+ E + RL+ R++ E +++K EE+E Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLK---REQEERLEQRLKREEVE 608 Score = 45.1 bits (105), Expect = 9e-05 Identities = 62/246 (25%), Positives = 116/246 (47%), Gaps = 36/246 (14%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 +++ER+ +Q E +Q++ E + + R + E +L+ + + R++ Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE-------QEEERREQ 375 Query: 79 ALVRE----RERQLAKRQHLE-EQRLQQERQ--REQEQRRERK-RKISCLSFALDDLDDQ 130 L RE RE+QL + Q L EQ+L++E+Q REQ+ RRE++ R+ L ++ + Sbjct: 376 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHE 435 Query: 131 ADAAEARRAGNLGKNPDVDTSFLP---DRDREEEENRLR-------EELRQEW-----EA 175 + RR L + + +L + +R E+E R + EE R+ W E Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495 Query: 176 QREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235 +RE+ + E ++ + +R R + +QQ L+ Q LR++ E R EQL Sbjct: 496 RREQQERREQQLRREQ-EERREQRLKRQEEEERLQQRLRSE-QQLRREQEERR----EQL 549 Query: 236 MFIKED 241 + +E+ Sbjct: 550 LKREEE 555 Score = 43.9 bits (102), Expect = 2e-04 Identities = 58/244 (23%), Positives = 109/244 (44%), Gaps = 30/244 (12%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 +++ER+R+ + K + EE +L + +KR + E + +++ +E Sbjct: 952 RRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEE----------ELQQEEE 1001 Query: 79 ALVRE----RERQLAKRQHLEEQRLQQERQR----EQEQRR--ERKRKISCLSFALDDLD 128 L+RE R RQ +RQ+ ++ LQQE ++ E+E+RR ER+R+ L + Sbjct: 1002 QLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYR-EEEELQQEE 1060 Query: 129 DQ--ADAAEARRAGNLGKNPDVDTSFLPDRD---REEEENRLREELRQEWEAQREKVKDE 183 +Q + E RR L + + + + REE E R R+E ++ + E ++E Sbjct: 1061 EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120 Query: 184 EMEVTFSYWDGSGHRRTVRVRKGNTVQ----QFLKKALQGLRKDFLELRSAGVEQLMFIK 239 E + + R+ VQ Q L++ + R+ LE + E+L + Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180 Query: 240 EDLI 243 E L+ Sbjct: 1181 EQLL 1184 Score = 43.5 bits (101), Expect = 3e-04 Identities = 42/169 (24%), Positives = 82/169 (48%), Gaps = 22/169 (13%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 ++RE+Q E+ E ++R +E + Q+ + + E +L+ + + R++ Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRRE---QEERREQQLRRE-------QEEERREQ 362 Query: 79 ALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRERKRKISCLSFALDDLDDQADAAEA 136 L RE+E + ++Q EQ+L++E+Q REQ+ RRE++ L + Sbjct: 363 QLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ---------LRREQQLRREQQL 413 Query: 137 RRAGNLGKNPDVDTSFLPDRDREEEENRLREE-LRQEWEAQREKVKDEE 184 RR L + + +R ++ E RE+ L++E E +R+ +K EE Sbjct: 414 RREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462 Score = 42.4 bits (98), Expect = 6e-04 Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 24/164 (14%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 ++RE+Q Q K R E+ + + + D++F V + +E Sbjct: 1402 QEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ----------------ERE 1445 Query: 79 ALVRERERQLAKRQHL---EEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAE 135 E E+QL + +H EE++L QER+ +Q R+ER RK F ++ + + Sbjct: 1446 RKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRK-----FLEEEQQLRRQERD 1500 Query: 136 ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179 + ++ + + FL + + + R R+ L++E + +R++ Sbjct: 1501 RKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQE 1544 Score = 40.4 bits (93), Expect = 0.002 Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 50/164 (30%) Query: 77 QEALVRERERQLAKRQ------HLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQ 130 +E+L+++R ++ +R+ LEE+ Q+ RQ+ QEQ RE L + ++Q Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE-----------LAEGEEQ 154 Query: 131 ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFS 190 ++ E L RDR+ + L + RQEW+ + E+ +EE Sbjct: 155 SEKQER----------------LEQRDRQRRDEELWRQ-RQEWQEREERRAEEEQ----- 192 Query: 191 YWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQ 234 ++ KG+ ++F + Q R++ LELR G E+ Sbjct: 193 ----------LQSCKGHETEEFPDEE-QLRRRELLELRRKGREE 225 Score = 40.4 bits (93), Expect = 0.002 Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 42/201 (20%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAV---EAELKSSTVGLVTLNDMKA 75 ++RERQ + E L+Q EE +L+ + +KR + E E++ L+ K Sbjct: 1104 QERERQCREEEELQQE--EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161 Query: 76 RQEALVRE--------RERQLAKRQHLEEQRLQQERQ-REQEQRRERKRKISCLSFALDD 126 R++ L R+ +E + R+ E++R ++ERQ RE+E+ + +KRK D Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRK-----QRYRD 1216 Query: 127 LDDQADAA---EARRAGNLGKNP------------DVDTSFLPDRDRE--------EEEN 163 D ++D E + + N ++ S L DR + E++ Sbjct: 1217 EDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQE 1276 Query: 164 RLREELRQEWEAQREKVKDEE 184 R RE+ R+ W+ + +EE Sbjct: 1277 RDREQERRRWQQRDRHFPEEE 1297 Score = 39.7 bits (91), Expect = 0.004 Identities = 44/175 (25%), Positives = 75/175 (42%), Gaps = 19/175 (10%) Query: 20 KRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA 79 KRE + E+ E Q +AEE + Q +R + + +L+S + + R++ Sbjct: 673 KREHEEERRE---QELAEEE--QEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727 Query: 80 LVRERERQLAKRQHLEEQRLQQERQR--EQEQRRERKRKISCLSFALDDLDDQADAAEAR 137 R R+ Q KR+ E + QE +R Q+Q E++R + A + + AR Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787 Query: 138 --------RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184 R + + FLP EEEE R R+E E + + +++EE Sbjct: 788 PPLREQRERQLRAEERQQREQRFLP----EEEEKEQRRRQRREREKELQFLEEEE 838 Score = 39.7 bits (91), Expect = 0.004 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 15/172 (8%) Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77 L++RER ++ E ++ +SQ +R +E E K TL A Q Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH---TLYAKPALQ 896 Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQ--ADAAE 135 E L +E+QL + + E QR ++E++R QEQ R+ + + L ++Q + E Sbjct: 897 EQL--RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQ-----LQQEEEQLLREERE 949 Query: 136 ARRAGNLGKNPDVDTSFLPDRDR---EEEENRLREELRQEWEAQREKVKDEE 184 RR + D ++ EE E R R+E +++ + E ++EE Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEE 1001 Score = 37.7 bits (86), Expect = 0.014 Identities = 33/169 (19%), Positives = 77/169 (45%), Gaps = 10/169 (5%) Query: 22 ERQREQMEVLKQRIAEETILKSQVDKRF----SAHYDAVEAELKSSTVGLVTLNDMKARQ 77 ER+ + E L+Q +E + + + ++ + E +L+ + + RQ Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781 Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137 E ++ Q + R+ EE++L+QER+ +Q + ++R K + ++ Q + E R Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGK-----YRWEEEQLQLEEQEQR 1836 Query: 138 RAGNLGKNPDVDTSFLP-DRDREEEENRLREELRQEWEAQREKVKDEEM 185 + + F ++ R EE+ +EE ++ + + K+++E + Sbjct: 1837 LRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHI 1885 Score = 35.8 bits (81), Expect = 0.053 Identities = 44/189 (23%), Positives = 82/189 (43%), Gaps = 30/189 (15%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 ++R RQR + E Q + EE Q+ +R A +L+ GL + + QE Sbjct: 818 EQRRRQRREREKELQFLEEE----EQLQRRERAQ------QLQEEEDGLQEDQERRRSQE 867 Query: 79 A---------LVRERERQ---------LAKRQHLEEQRLQQERQR-EQEQRRERKRKISC 119 L ER+R+ L ++ E+Q LQ+E + ++E+R +R+R+ Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927 Query: 120 LSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRD-REEEENRLREELRQEWEAQRE 178 + ++ Q + R + + + + D+ +++EE L EE + +RE Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQERE 987 Query: 179 KVKDEEMEV 187 K EE E+ Sbjct: 988 KKYREEEEL 996 Score = 35.4 bits (80), Expect = 0.070 Identities = 22/96 (22%), Positives = 47/96 (48%), Gaps = 7/96 (7%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 ++ +R+ + E L+Q E+ + Q D ++ + ++ E + + +A ++ Sbjct: 1791 QESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850 Query: 79 ALVRERERQLAKRQHLEEQRLQQERQREQEQRRERK 114 +E+ R+ EEQ L QE ++++ Q RERK Sbjct: 1851 FATQEKSRR-------EEQELWQEEEQKRRQERERK 1879 Score = 31.2 bits (69), Expect = 1.3 Identities = 32/115 (27%), Positives = 53/115 (46%), Gaps = 9/115 (7%) Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQA 131 D + +E R R+++ + + L E Q E+Q EQ R+R+R+ L + ++ Sbjct: 126 DRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQ-RDRQRRDEELWRQRQEWQER- 183 Query: 132 DAAEARRA--GNLGKNPDVDTSFLPDRD--REEEENRLREELRQEWEAQREKVKD 182 E RRA L +T PD + R E LR + R+E + QR + +D Sbjct: 184 ---EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQD 235 Score = 29.3 bits (64), Expect = 5.0 Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 11/104 (10%) Query: 17 LLKKRERQ--REQMEVLKQRIAEETILKSQVDKRFSAHYDA-VEAELKSSTVGLVTLNDM 73 L ++RE Q R Q K R EE + + ++R D AE + +T Sbjct: 1803 LRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT-------QE 1855 Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKI 117 K+R+E +E + +RQ E++L++E R Q++ +R R++ Sbjct: 1856 KSRREEQELWQEEEQKRRQE-RERKLREEHIRRQQKEEQRHRQV 1898 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 55.8 bits (133), Expect = 5e-08 Identities = 50/184 (27%), Positives = 83/184 (45%), Gaps = 9/184 (4%) Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSST 64 K RE R ++RER+RE+ ++ E + + DK+ D +A + Sbjct: 387 KSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRK- 445 Query: 65 VGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFAL 124 L +EA +ER + R+ + + ++E +RE+E+RRE ++ L L Sbjct: 446 -----LERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFL 500 Query: 125 DDLDDQADAAEARRAGNLGKN-PDVDTSFLPD-RDREEEENRLREELRQEWEAQREKVKD 182 +D DD D + R L K D + D RDR+ E+ L EE+RQ A+ D Sbjct: 501 EDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL-EEIRQRLLAEGHPDPD 559 Query: 183 EEME 186 E++ Sbjct: 560 AELQ 563 Score = 55.1 bits (131), Expect = 8e-08 Identities = 41/163 (25%), Positives = 75/163 (46%), Gaps = 4/163 (2%) Query: 25 REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALVRER 84 +E + ++ + ++ ++ K H E + K + + R+ RER Sbjct: 261 KEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERER 320 Query: 85 ERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGK 144 ER+ +R+ E+ ++E++RE+E+ R+R R + D D+ + R + + Sbjct: 321 ERREREREREREREREKEKERERERERDRDRD---RTKERDRDRDRERDRDRDRERSSDR 377 Query: 145 NPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186 N D S RDRE E R RE E +E E +RE+ ++ E E Sbjct: 378 NKDRSRSREKSRDRERERERERERERERERERERERERERERE 420 Score = 47.0 bits (110), Expect = 2e-05 Identities = 53/207 (25%), Positives = 95/207 (45%), Gaps = 35/207 (16%) Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68 RE R K+RER+RE + R + T + D+ D +SS Sbjct: 329 REREREREKEKERERERE-----RDRDRDRT---KERDRDRDRERDRDRDRERSSDRNK- 379 Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD 128 + ++R+++ RERER+ + + E +R ++ER+RE+E+ RER+R+ D + Sbjct: 380 --DRSRSREKSRDRERERERERERERERER-ERERERERERERERERERE-KDKKRDREE 435 Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE-AQREKVKDEEMEV 187 D+ DA E R+ +R E+E +E L+ WE +R+K ++ E E Sbjct: 436 DEEDAYERRKL---------------ERKLREKEAAYQERLK-NWEIRERKKTREYEKEA 479 Query: 188 TFSYWDGSGHRRTVRVRKGNTVQQFLK 214 + RR ++ +++FL+ Sbjct: 480 -----EREEERRREMAKEAKRLKEFLE 501 Score = 32.3 bits (72), Expect = 0.59 Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 28/94 (29%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 + R+R++E++E ++QR+ E H D +AEL+ + QE Sbjct: 534 RDRKREKEELEEIRQRLLAE------------GHPDP-DAELQ------------RMEQE 568 Query: 79 ALVRERERQLAKRQHLEEQRLQQERQREQEQRRE 112 A ER RQ +Q E + ++E+Q ++E+R E Sbjct: 569 A---ERRRQPQIKQEPESEEEEEEKQEKEEKREE 599 >gi|205277396 dynactin 1 isoform 4 [Homo sapiens] Length = 1139 Score = 52.0 bits (123), Expect = 7e-07 Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%) Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74 ++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L + Sbjct: 182 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 233 Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128 AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L Sbjct: 234 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 293 Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171 +Q DAA E NL V D + + + E +EN ELR+ Sbjct: 294 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 353 Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231 + + +V++ + V + + +++T++ + T LQ + ++ + A Sbjct: 354 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 407 Query: 232 VEQ 234 VE+ Sbjct: 408 VER 410 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%) Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104 S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q Sbjct: 80 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 139 Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163 R +E R+E K + ++++ D ADA E + D+E E Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 182 Query: 164 RLREELRQEWEAQREKVKD 182 R E L+QE EA +E+V + Sbjct: 183 R-AESLQQEVEALKERVDE 200 >gi|205277392 dynactin 1 isoform 3 [Homo sapiens] Length = 1253 Score = 52.0 bits (123), Expect = 7e-07 Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%) Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74 ++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L + Sbjct: 296 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 347 Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128 AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L Sbjct: 348 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 407 Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171 +Q DAA E NL V D + + + E +EN ELR+ Sbjct: 408 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 467 Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231 + + +V++ + V + + +++T++ + T LQ + ++ + A Sbjct: 468 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 521 Query: 232 VEQ 234 VE+ Sbjct: 522 VER 524 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%) Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104 S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q Sbjct: 194 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 253 Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163 R +E R+E K + ++++ D ADA E + D+E E Sbjct: 254 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 296 Query: 164 RLREELRQEWEAQREKVKD 182 R E L+QE EA +E+V + Sbjct: 297 R-AESLQQEVEALKERVDE 314 >gi|13259508 dynactin 1 isoform 2 [Homo sapiens] Length = 1144 Score = 52.0 bits (123), Expect = 7e-07 Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%) Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74 ++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L + Sbjct: 182 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 233 Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128 AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L Sbjct: 234 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 293 Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171 +Q DAA E NL V D + + + E +EN ELR+ Sbjct: 294 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 353 Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231 + + +V++ + V + + +++T++ + T LQ + ++ + A Sbjct: 354 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 407 Query: 232 VEQ 234 VE+ Sbjct: 408 VER 410 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%) Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104 S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q Sbjct: 80 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 139 Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163 R +E R+E K + ++++ D ADA E + D+E E Sbjct: 140 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 182 Query: 164 RLREELRQEWEAQREKVKD 182 R E L+QE EA +E+V + Sbjct: 183 R-AESLQQEVEALKERVDE 200 >gi|13259510 dynactin 1 isoform 1 [Homo sapiens] Length = 1278 Score = 52.0 bits (123), Expect = 7e-07 Identities = 58/243 (23%), Positives = 120/243 (49%), Gaps = 41/243 (16%) Query: 19 KKRERQREQMEVLKQRIAEET----ILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74 ++ E ++++E LK+R+ E T ILK++++++ S + +S+ L L + Sbjct: 316 ERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS--------DGAASSYQLKQLEEQN 367 Query: 75 AR-QEALVRERERQLAKRQ-HLEEQRLQQERQREQE---QRRER-KRKISCLSFALDDLD 128 AR ++ALVR R+ +++Q H++ Q+L +++ +E E Q+RER + ++S +D+L Sbjct: 368 ARLKDALVRMRDLSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELK 427 Query: 129 DQADAA-------EARRAGNLGKNPDV--------DTSFLPDRDREEEEN--RLREELRQ 171 +Q DAA E NL V D + + + E +EN ELR+ Sbjct: 428 EQVDAALGAEEMVEMLTDRNLNLEEKVRELRETVGDLEAMNEMNDELQENARETELELRE 487 Query: 172 EWEAQREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAG 231 + + +V++ + V + + +++T++ + T LQ + ++ + A Sbjct: 488 QLDMAGARVREAQKRVEAAQETVADYQQTIKKYRQLTAH------LQDVNRELTNQQEAS 541 Query: 232 VEQ 234 VE+ Sbjct: 542 VER 544 Score = 39.3 bits (90), Expect = 0.005 Identities = 33/139 (23%), Positives = 63/139 (45%), Gaps = 24/139 (17%) Query: 50 SAHYDAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQ----- 104 S + + A+++ L TL +A +A ++E E+ + + ++E + + + Q Sbjct: 214 SKEEEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQ 273 Query: 105 -REQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN 163 R +E R+E K + ++++ D ADA E + D+E E Sbjct: 274 RRLKEARKEAKEALEAKERYMEEMADTADAIE-----------------MATLDKEMAEE 316 Query: 164 RLREELRQEWEAQREKVKD 182 R E L+QE EA +E+V + Sbjct: 317 R-AESLQQEVEALKERVDE 334 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 52.0 bits (123), Expect = 7e-07 Identities = 36/113 (31%), Positives = 55/113 (48%), Gaps = 26/113 (23%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133 + R+ RER+R+ K + LE +R + ER+RE+E+ R+R+R D D D Sbjct: 687 RERERERERERDREREKERELERERAR-EREREREKERDRER----------DRDRDHDR 735 Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 R +RDRE+E R REE +E E +RE+ ++ E E Sbjct: 736 ERERER---------------ERDREKEREREREERERERERERERERERERE 773 Score = 46.6 bits (109), Expect = 3e-05 Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 1/117 (0%) Query: 71 NDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD-D 129 ND R E R ++ R+ + +ER+R++E+ RER+R+ +L+ + Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERE 710 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 +A E R + D D +R+RE E +R +E R+ E +RE+ ++ E E Sbjct: 711 RAREREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERE 767 Score = 39.7 bits (91), Expect = 0.004 Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 9/108 (8%) Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68 RE R ++RER+RE+ E ++R E + + + +R E E + Sbjct: 677 RERDRERERDRERERERER-ERDREREKERELERERARER--------EREREKERDRER 727 Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116 + R+ RER+R+ + + EE+ ++ER+RE+E+ RER+R+ Sbjct: 728 DRDRDHDRERERERERDREKEREREREERERERERERERERERERERE 775 Score = 38.9 bits (89), Expect = 0.006 Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 11/104 (10%) Query: 84 RERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLG 143 RER + Q E +R++ RRE +R +D +DD+ D R Sbjct: 635 RERDQRPSSPIRHQGRNDELERDE--RREERR--------VDRVDDRRDERARERDRERE 684 Query: 144 KNPDVDTSFLPDRDRE-EEENRLREELRQEWEAQREKVKDEEME 186 ++ + + +RDRE E+E L E +E E +REK +D E + Sbjct: 685 RDRERERERERERDREREKERELERERAREREREREKERDRERD 728 Score = 34.3 bits (77), Expect = 0.16 Identities = 41/179 (22%), Positives = 75/179 (41%), Gaps = 5/179 (2%) Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68 RE R K+RER+RE+ E ++R E + + +R + D + Sbjct: 737 RERERERDREKEREREREERERERERERERERERERERER-ARERDKERERQRDWEDKDK 795 Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD 128 +D + ++E + +R + + ++R + E Q +R+R+ S S A + D Sbjct: 796 GRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGD 855 Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEV 187 D+ E R + P S P E+ + R +EE R+ E + + EE E+ Sbjct: 856 DK---NEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKP-ERKESSRRYEEQEL 910 Score = 31.6 bits (70), Expect = 1.0 Identities = 29/108 (26%), Positives = 47/108 (43%), Gaps = 27/108 (25%) Query: 81 VRERERQLAKRQHLEEQ-RLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRA 139 V R R L+E+ R + +R+RE+E+R R+R + D AD R Sbjct: 1286 VHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQR----------EWDRDADKDWPRNR 1335 Query: 140 GNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186 DRDR E R RE + R++ + +RE++ + +E Sbjct: 1336 ---------------DRDRLRERERERERDKRRDLDRERERLISDSVE 1368 Score = 28.9 bits (63), Expect = 6.5 Identities = 27/102 (26%), Positives = 47/102 (46%), Gaps = 10/102 (9%) Query: 83 ERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLD--------DQADAA 134 ER Q R+H + + +R RE++ R ER+ + S + D D D+ DA Sbjct: 404 ERTSQSHDRRHERREDTRGKRDREKDSREEREYE-QDQSSSRDHRDDREPRDGRDRRDAR 462 Query: 135 EARRAGNLGKNPDV-DTSFLPDRDREEEENRLREELRQEWEA 175 + R L + D+ D+ + D R+ +E+R + R +A Sbjct: 463 DTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDA 504 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 51.2 bits (121), Expect = 1e-06 Identities = 39/170 (22%), Positives = 83/170 (48%), Gaps = 17/170 (10%) Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77 +++ +++R + E + E +K++ DK+ + +EAE K++ + R+ Sbjct: 257 MEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAA-------QERERR 309 Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDL-DDQADAAEA 136 EA RER R+ KR E QR+++E +R E+R+ K + + + +++ AAE Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369 Query: 137 RRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 R+ + ++ + EE+ R ++ ++ Q K+K E++E Sbjct: 370 RQRARAEEE---------EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVE 410 Score = 40.0 bits (92), Expect = 0.003 Identities = 41/168 (24%), Positives = 75/168 (44%), Gaps = 16/168 (9%) Query: 20 KRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA 79 + R+R + E L+Q+ EE++ + +A + E K++T T ++ EA Sbjct: 39 RERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTT----TNTQVEGDDEA 94 Query: 80 LVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRA 139 ER LA+R+ ++RLQ+ +R+ +E I+ S +L Q D AE Sbjct: 95 AFLER---LARREERRQKRLQEALERQ----KEFDPTITDASLSLPSRRMQNDTAENETT 147 Query: 140 GNLGKNPDVDTSFLPDRDREEEENRLREELRQEW-EAQREKVKDEEME 186 K+ + + EE E + + +W +A+ K +D+E E Sbjct: 148 EKEEKSESRQERY----EIEETETVTKSYQKNDWRDAEENKKEDKEKE 191 Score = 36.6 bits (83), Expect = 0.031 Identities = 35/180 (19%), Positives = 81/180 (45%), Gaps = 12/180 (6%) Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69 E A ++ +RE+M ++R AEE + +KR + ++ E K + Sbjct: 299 EKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA---EE 355 Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 +K ++ ER+R A+ EE++ + E Q+ +Q E+K + + ++ Sbjct: 356 RQRIKEEEKRAAEERQRARAE----EEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQ 411 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREE--EENRLREELRQEWEA-QREKVKDEEME 186 + + + + T+ L + E+ + RE+L+++ ++E++KDE+++ Sbjct: 412 KIEGKWVNE--KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIK 469 Score = 34.3 bits (77), Expect = 0.16 Identities = 36/166 (21%), Positives = 71/166 (42%), Gaps = 19/166 (11%) Query: 23 RQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALVR 82 +Q E+ E I+ ++ + +R A +EAE +E + Sbjct: 239 KQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAE----------------ERERIKA 282 Query: 83 ERERQLA-KRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGN 141 E+++++A +R +E + ++RE+ + ER+R A ++ + E R A Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEE-RQRIKEEEKRAAEE 341 Query: 142 LGKNPDVDTSFLPDRDR-EEEENRLREELRQEWEAQREKVKDEEME 186 + + + +R R +EEE R EE ++ + EK K EE + Sbjct: 342 RQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQK 387 Score = 31.6 bits (70), Expect = 1.0 Identities = 27/120 (22%), Positives = 54/120 (45%), Gaps = 15/120 (12%) Query: 70 LNDMKARQEALVRERERQLAKRQHL--------EEQRLQQERQREQEQRRERKRKISCLS 121 ++D + R+E ++RE + + + EE+ ++ R+R +++R +K++ L Sbjct: 1 MDDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLG 60 Query: 122 FALDDLDDQA-----DAAEARRAGNLGKNPDVDTSFLPDRDREEE--ENRLREELRQEWE 174 D ++ A D N D + +FL R EE + RL+E L ++ E Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKE 120 Score = 28.9 bits (63), Expect = 6.5 Identities = 44/185 (23%), Positives = 76/185 (41%), Gaps = 46/185 (24%) Query: 18 LKKRERQREQMEVLKQRIAEETILKSQ-----------VDKRFS-----AHYDAVEAELK 61 +KK + +E+++ R T +KSQ + FS A D EAE Sbjct: 468 IKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGA 527 Query: 62 SSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLS 121 L +++ R+ E +L ++Q +E L+ E E +++RE +RK+ Sbjct: 528 PQVEAGKRLEELRRRRGETESEEFEKLKQKQ--QEAALELE---ELKKKREERRKV---- 578 Query: 122 FALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREEL---RQEWEAQRE 178 + E RR K + D EEE+ RL+EE+ R E +R+ Sbjct: 579 ---------LEEEEQRR-----KQEEADRKLR----EEEEKRRLKEEIERRRAEAAEKRQ 620 Query: 179 KVKDE 183 K+ ++ Sbjct: 621 KMPED 625 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 50.1 bits (118), Expect = 3e-06 Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 23/138 (16%) Query: 74 KARQEALVRERERQLAKRQHLEEQR-----LQQERQREQEQRRERKRKISCLSFALDDLD 128 + R+ RERER+ +++ E +R Q+E +R++E+ RERKRK Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK----------RQ 348 Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME-V 187 + D R+ G G+ +R+RE E R R+ R+ E +R++ +D + E Sbjct: 349 TEMDRERNRQTGREGRRQ-------AERERERERERDRQSAREREERERDRDRDRQKERE 401 Query: 188 TFSYWDGSGHRRTVRVRK 205 + D G R T + R+ Sbjct: 402 RQTEKDRDGQRETEKQRE 419 Score = 49.3 bits (116), Expect = 5e-06 Identities = 56/204 (27%), Positives = 86/204 (42%), Gaps = 28/204 (13%) Query: 7 TMREAGRAMHLLKKRERQRE-------QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAE 59 T RE R ++RE+Q E + E K+R E + + D+R + + Sbjct: 228 TDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR-DRRQKERERQTDRK 286 Query: 60 LKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQR---LQQERQREQEQRRERKRK 116 + T + RQ RERER + + E +R Q+E +R++E+ RERKRK Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK 346 Query: 117 ISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEE-----NRLREELRQ 171 +D ++ E RR + + + R+REE E +R +E RQ Sbjct: 347 RQT---EMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403 Query: 172 ---------EWEAQREKVKDEEME 186 E E QRE+ KD E E Sbjct: 404 TEKDRDGQRETEKQREREKDRESE 427 Score = 47.0 bits (110), Expect = 2e-05 Identities = 47/183 (25%), Positives = 82/183 (44%), Gaps = 13/183 (7%) Query: 9 REAGRAMHLLKKRERQRE-QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67 RE R + RERQR+ + E +Q E + + R E E + Sbjct: 83 REKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQ 142 Query: 68 VTLNDMKARQEALVRERERQL-AKRQHLEEQRLQQERQRE--QEQRRERKRKISCLSFAL 124 + RQ +ERERQ +RQ E+ Q+ER+RE +++RRER+R+ Sbjct: 143 TDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ-------- 194 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDE 183 + +++ + + R + + +T R + E +R R+ E +E +A+RE+ + Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254 Query: 184 EME 186 E E Sbjct: 255 ETE 257 Score = 46.2 bits (108), Expect = 4e-05 Identities = 49/194 (25%), Positives = 76/194 (39%), Gaps = 48/194 (24%) Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAE-------------ETILKSQVDKRFSAHYDA 55 RE + ++RERQRE+ + R +E ET K Q D+ Sbjct: 179 REREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKT 238 Query: 56 VEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115 K + R+ A RE ER + + + R + RQ+E+E++ +RKR Sbjct: 239 EREREKQAE-----------RERASERETERDKERERERDRDRDRDRRQKERERQTDRKR 287 Query: 116 KISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE---ELRQE 172 + + D + + R+ +R+RE E NR RE E +E Sbjct: 288 Q------RRTERDRETERKRERQR---------------ERERERERNRKRERERERERE 326 Query: 173 WEAQREKVKDEEME 186 E QRE +D E E Sbjct: 327 RERQRETERDREKE 340 Score = 42.0 bits (97), Expect = 7e-04 Identities = 33/115 (28%), Positives = 56/115 (48%), Gaps = 4/115 (3%) Query: 76 RQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAE 135 R+ +ERER+ KRQ E ++ER+RE+++ R+R R + + Q D Sbjct: 54 RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113 Query: 136 AR---RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ-EWEAQREKVKDEEME 186 R + N K + +T +R R+ + + RE RQ + E +RE+ D E + Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQ 168 Score = 42.0 bits (97), Expect = 7e-04 Identities = 44/164 (26%), Positives = 75/164 (45%), Gaps = 20/164 (12%) Query: 9 REAGRAMHLLKKRERQRE-QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67 RE R +KRER+RE + E +QR E K + KR E ++ G Sbjct: 305 RERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREG- 363 Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDL 127 R+ RER+RQ A+ +R ++ER R++++++ER+R+ D Sbjct: 364 ---RRQAERERERERERDRQSAR------EREERERDRDRDRQKERERQTE------KDR 408 Query: 128 DDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ 171 D Q + + R K+ + + R+RE+++ R R+ RQ Sbjct: 409 DGQRETEKQRER---EKDRESERGRERGREREKQKGRERDRERQ 449 Score = 38.1 bits (87), Expect = 0.011 Identities = 32/113 (28%), Positives = 58/113 (51%), Gaps = 12/113 (10%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133 +A ++A +RER K + E +R +++ +RE +++RER+R+ D + D Sbjct: 44 QAHKDADGDDRERNRQKER--ERRREKRQTERETDRKRERRRE--------KDRHRKRDR 93 Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 R+ + K + T DR RE+E NR +E R E E + E+ +D + + Sbjct: 94 HRERQR-DREKERERQTDRERDRQREKERNRQKERER-ETEREGERGRDRQTD 144 Score = 38.1 bits (87), Expect = 0.011 Identities = 33/123 (26%), Positives = 60/123 (48%), Gaps = 11/123 (8%) Query: 72 DMKARQEALV------RERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125 + + R+E R+RER+ K +H + R +ERQR++E+ RER+ Sbjct: 61 ERERRREKRQTERETDRKRERRREKDRHRKRDR-HRERQRDREKERERQTDRERDRQREK 119 Query: 126 DLDDQAD-AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE---ELRQEWEAQREKVK 181 + + Q + E R G G++ D +R R+ E+ R R+ E +++ E R+K + Sbjct: 120 ERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER 179 Query: 182 DEE 184 + E Sbjct: 180 ERE 182 Score = 29.6 bits (65), Expect = 3.8 Identities = 24/114 (21%), Positives = 53/114 (46%), Gaps = 9/114 (7%) Query: 7 TMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVG 66 T RE R ++RER+R++ ++ E + + +R E + + G Sbjct: 359 TGREGRRQAERERERERERDRQSAREREERERDRDRDRQKER--------ERQTEKDRDG 410 Query: 67 LVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120 + R++ ER R+ + + ++ R +++R+R+ +++ R+RK S L Sbjct: 411 QRETEKQREREKDRESERGRERGREREKQKGR-ERDRERQTDRQAGRQRKRSTL 463 Score = 28.5 bits (62), Expect = 8.5 Identities = 27/107 (25%), Positives = 43/107 (40%), Gaps = 3/107 (2%) Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68 R+ GR +RER+RE+ + E + + R E + Sbjct: 357 RQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416 Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115 K R+ RER R+ K++ E R ERQ +++ R+RKR Sbjct: 417 QREREKDRESERGRERGREREKQKGRERDR---ERQTDRQAGRQRKR 460 >gi|148839339 nexilin (F actin binding protein) [Homo sapiens] Length = 675 Score = 49.3 bits (116), Expect = 5e-06 Identities = 44/205 (21%), Positives = 97/205 (47%), Gaps = 16/205 (7%) Query: 6 GTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65 GT++ M ++ E+++ E K+RI ++ + K ++ + + + +E + T Sbjct: 100 GTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLEKRKIQRELAKRAEQIEDINNTGTE 159 Query: 66 G---------LVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQRE--QEQRRERK 114 L+T+ +K+ + + ++ + +++ E++R++ E + E++R Sbjct: 160 SASEEGDDSLLITVVPVKSYKTSGKMKKNFEDLEKEREEKERIKYEEDKRIRYEEQRPSL 219 Query: 115 RKISCLSFALDDLDDQADAAEARRAGNLGKN-PDVDTSFLPDRDREEEE---NRLREELR 170 ++ CLS +DD + E+ G L +++ +R ++ EE RL EE R Sbjct: 220 KEAKCLSLVMDDEIESEAKKESLSPGKLKLTFEELERQRQENRKKQAEEEARKRLEEEKR 279 Query: 171 QEWEAQREKV-KDEEMEVTFSYWDG 194 EA+R+ V +DEE + T + G Sbjct: 280 AFEEARRQMVNEDEENQDTAKIFKG 304 Score = 41.6 bits (96), Expect = 0.001 Identities = 32/115 (27%), Positives = 59/115 (51%), Gaps = 9/115 (7%) Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQA 131 D+K + EA+ R RE + +R E+QR +++ RE+E R RK++I + A DD +D + Sbjct: 30 DVKDKFEAMQRAREERNQRRSRDEKQRRKEQYIREREWNR-RKQEIKEM-LASDDEEDVS 87 Query: 132 DAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 E L T + R E E+ R E+ ++ E ++ +++ + +E Sbjct: 88 SKVEKAYVPKL-------TGTVKGRFAEMEKQRQEEQRKRTEEERKRRIEQDMLE 135 Score = 34.3 bits (77), Expect = 0.16 Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 4/101 (3%) Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77 L ++E Q++ E +R A + +K + + F D + S +MKAR Sbjct: 458 LSEKEIQKKIEEERARRRAIDLEIKEREAENFHEEDDVDVRPARKSEAPFTHKVNMKARF 517 Query: 78 EALVRERERQLAKRQHLEEQRL--QQERQREQEQRRERKRK 116 E + + RE + +++ +EEQ+L Q QRE + ++KR+ Sbjct: 518 EQMAKAREEE--EQRRIEEQKLLRMQFEQREIDAALQKKRE 556 Score = 31.2 bits (69), Expect = 1.3 Identities = 34/172 (19%), Positives = 76/172 (44%), Gaps = 10/172 (5%) Query: 22 ERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEALV 81 E +R++ E K++ EE + + +KR A +A + T K + + Sbjct: 253 ELERQRQENRKKQAEEEARKRLEEEKR--AFEEARRQMVNEDEENQDTAKIFKGYRPGKL 310 Query: 82 RERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGN 141 + ++ +++ +E+R +E R + + ++ + + +DD + ++ Sbjct: 311 KLSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSPEMYKTISQEFLT 370 Query: 142 LGKNPDVDTSFLPDRDREEEENRLREELR-------QEWEAQREKVKDEEME 186 GK +++ L + EEE+ R EE + QE+E R+++ +EE E Sbjct: 371 PGKL-EINFEELLKQKMEEEKRRTEEERKHKLEMEKQEFEQLRQEMGEEEEE 421 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 48.9 bits (115), Expect = 6e-06 Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E Sbjct: 743 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 786 Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124 AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A Sbjct: 787 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 846 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184 ++ + Q E R ++ R EEE R E++++ E R++ + +E Sbjct: 847 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 898 Score = 47.8 bits (112), Expect = 1e-05 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%) Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 +M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL + Sbjct: 739 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 793 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 Q A +R + + L +R REEEE R +EEL ++ E + K EE E Sbjct: 794 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 850 Score = 40.8 bits (94), Expect = 0.002 Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%) Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65 EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+ Sbjct: 865 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 922 Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125 N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L Sbjct: 923 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 969 Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 Q + GN+ K P T L + +EE +++ +Q+ Q + ++ Sbjct: 970 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1025 Score = 36.6 bits (83), Expect = 0.031 Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%) Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69 EA R + ++ E +R + E L ++ EE ++ ++ + ++ L Sbjct: 812 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 871 Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 + + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S + Sbjct: 872 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 927 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181 A +++ +L + ++ EE E +LREE R++ QRE +K Sbjct: 928 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 967 Score = 33.1 bits (74), Expect = 0.35 Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%) Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76 +Q + LK RI+++ I+ S V + S EL+ + D Sbjct: 655 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 713 Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130 AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ + Sbjct: 714 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 773 Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185 + E ARR + R REEEE + +EE + E +R E+ K EE+ Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 833 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 48.9 bits (115), Expect = 6e-06 Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E Sbjct: 770 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 813 Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124 AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A Sbjct: 814 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 873 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184 ++ + Q E R ++ R EEE R E++++ E R++ + +E Sbjct: 874 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 925 Score = 47.8 bits (112), Expect = 1e-05 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%) Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 +M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL + Sbjct: 766 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 820 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 Q A +R + + L +R REEEE R +EEL ++ E + K EE E Sbjct: 821 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 877 Score = 40.8 bits (94), Expect = 0.002 Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%) Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65 EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+ Sbjct: 892 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 949 Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125 N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L Sbjct: 950 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 996 Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 Q + GN+ K P T L + +EE +++ +Q+ Q + ++ Sbjct: 997 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1052 Score = 36.6 bits (83), Expect = 0.031 Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%) Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69 EA R + ++ E +R + E L ++ EE ++ ++ + ++ L Sbjct: 839 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 898 Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 + + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S + Sbjct: 899 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 954 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181 A +++ +L + ++ EE E +LREE R++ QRE +K Sbjct: 955 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 994 Score = 33.1 bits (74), Expect = 0.35 Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%) Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76 +Q + LK RI+++ I+ S V + S EL+ + D Sbjct: 682 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 740 Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130 AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ + Sbjct: 741 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 800 Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185 + E ARR + R REEEE + +EE + E +R E+ K EE+ Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 860 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 48.9 bits (115), Expect = 6e-06 Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E Sbjct: 749 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 792 Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124 AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184 ++ + Q E R ++ R EEE R E++++ E R++ + +E Sbjct: 853 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 904 Score = 47.8 bits (112), Expect = 1e-05 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%) Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 +M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL + Sbjct: 745 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 799 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 Q A +R + + L +R REEEE R +EEL ++ E + K EE E Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 856 Score = 40.8 bits (94), Expect = 0.002 Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%) Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65 EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+ Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 928 Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125 N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L Sbjct: 929 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 975 Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 Q + GN+ K P T L + +EE +++ +Q+ Q + ++ Sbjct: 976 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031 Score = 36.6 bits (83), Expect = 0.031 Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%) Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69 EA R + ++ E +R + E L ++ EE ++ ++ + ++ L Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 877 Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 + + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S + Sbjct: 878 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 933 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181 A +++ +L + ++ EE E +LREE R++ QRE +K Sbjct: 934 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 973 Score = 33.1 bits (74), Expect = 0.35 Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%) Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76 +Q + LK RI+++ I+ S V + S EL+ + D Sbjct: 661 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 719 Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130 AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ + Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779 Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185 + E ARR + R REEEE + +EE + E +R E+ K EE+ Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839 >gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 48.9 bits (115), Expect = 6e-06 Identities = 47/180 (26%), Positives = 87/180 (48%), Gaps = 38/180 (21%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 K+ E +R++ E L+++ +E IL+ Q ++ + A K ++E Sbjct: 749 KREEEERKRQEELRRQ--QEEILRRQQEEERKRREEEELARRK--------------QEE 792 Query: 79 ALVRERERQLA-KRQHLEEQRLQQ--------ERQREQEQRRE-----RKRKISCLSFAL 124 AL R+RE+++A +RQ EE+R QQ ER+RE+E+RR+ RK++ +A Sbjct: 793 ALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAR 852 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEE 184 ++ + Q E R ++ R EEE R E++++ E R++ + +E Sbjct: 853 EEEEAQRRLEENRLR--------MEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQE 904 Score = 47.8 bits (112), Expect = 1e-05 Identities = 35/117 (29%), Positives = 62/117 (52%), Gaps = 7/117 (5%) Query: 72 DMKARQEALVRERERQLAKRQH--LEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 +M+A++E R+R+ +L ++Q L Q+ ++ ++RE+E+ RK++ AL + Sbjct: 745 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQE-----EALRRQRE 799 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 Q A +R + + L +R REEEE R +EEL ++ E + K EE E Sbjct: 800 QEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEE 856 Score = 40.8 bits (94), Expect = 0.002 Identities = 42/177 (23%), Positives = 80/177 (45%), Gaps = 20/177 (11%) Query: 10 EAGRAMHLLKKRERQ----REQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTV 65 EA R H ++R+R+ + Q E+++QR ++ L+ ++ + +L SS+ Sbjct: 871 EAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQ--QQQQLAQMKLPSSST 928 Query: 66 GLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125 N + +A + LA+ Q LEE+R ERQ +EQRR+++ + L Sbjct: 929 WGQQSNTTACQSQATL-----SLAEIQKLEEER---ERQLREEQRRQQRELMKAL----- 975 Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 Q + GN+ K P T L + +EE +++ +Q+ Q + ++ Sbjct: 976 QQQQQQQQQKLSGWGNVSK-PSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARN 1031 Score = 36.6 bits (83), Expect = 0.031 Identities = 35/172 (20%), Positives = 77/172 (44%), Gaps = 16/172 (9%) Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVT 69 EA R + ++ E +R + E L ++ EE ++ ++ + ++ L Sbjct: 818 EALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRH 877 Query: 70 LNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDD 129 + + R+E V+ ++ + +RQ +E + ++Q++Q+Q + K S + Sbjct: 878 EEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLP----SSSTWGQQS 933 Query: 130 QADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVK 181 A +++ +L + ++ EE E +LREE R++ QRE +K Sbjct: 934 NTTACQSQATLSLAEIQKLE---------EERERQLREEQRRQ---QRELMK 973 Score = 33.1 bits (74), Expect = 0.35 Identities = 44/180 (24%), Positives = 78/180 (43%), Gaps = 21/180 (11%) Query: 26 EQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLN---------DMKAR 76 +Q + LK RI+++ I+ S V + S EL+ + D Sbjct: 661 QQFQTLKMRISDQNIIPS-VTRSVSVPDTGSIWELQPTASQPTVWEGGSVWDLPLDTTTP 719 Query: 77 QEALVRERERQLAKRQHLEEQRLQQERQ--REQEQRRE----RKRKISCLSFALDDLDDQ 130 AL + ++ + AK LE++R + E + RE+E+R+ R+++ L ++ + Sbjct: 720 GPALEQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779 Query: 131 ADAAE-ARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR----EKVKDEEM 185 + E ARR + R REEEE + +EE + E +R E+ K EE+ Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEEL 839 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 48.9 bits (115), Expect = 6e-06 Identities = 43/181 (23%), Positives = 91/181 (50%), Gaps = 15/181 (8%) Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67 +RE MH ++E+ REQ E +R EE I + + + A E +++ + Sbjct: 346 IRELEEKMH---EQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 399 Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDD 126 +M QE + E+E ++ +++ EE + Q+E+ R QE++ RE+++KI + + Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQE--EEMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 457 Query: 127 LDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKDE 183 ++ E + GK + + +++EE+ R E++R++ + Q EK++++ Sbjct: 458 QEEMMQEQEEKMGEQEGKMCEQEAKM---QEQEEKMRRQEEKIREQEKKIREQEEKIREQ 514 Query: 184 E 184 E Sbjct: 515 E 515 Score = 42.0 bits (97), Expect = 7e-04 Identities = 40/182 (21%), Positives = 86/182 (47%), Gaps = 14/182 (7%) Query: 18 LKKRERQREQMEV--LKQRIAEETILKSQVDKRFSAHY-----DAVEAELKSSTVGLVTL 70 L + E+ Q+ V LK+++ +L Q + A + +V A+L++ Sbjct: 220 LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELW 279 Query: 71 NDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQ 130 N + +QE + +E ++ +R+ E+ + Q+E+ REQE++ R+ ++ ++ Sbjct: 280 NRLNQQQEEKMWRQEEKIQERE--EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEE 337 Query: 131 ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEA----QREKVKDEEM 185 + + L + ++ +EE ++RE E RQE EA Q EK++++E Sbjct: 338 MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEE 397 Query: 186 EV 187 ++ Sbjct: 398 KI 399 Score = 41.6 bits (96), Expect = 0.001 Identities = 40/168 (23%), Positives = 77/168 (45%), Gaps = 25/168 (14%) Query: 19 KKRERQREQMEVLKQRIAE-ETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77 +K RQ E+++ +++I E E ++ Q +K E E K RQ Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMR------------RQ 335 Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137 E ++ E+E ++ + LEE+ +QE+ REQE++R+ + KI ++ EA+ Sbjct: 336 EEMMWEKEEKI---RELEEKMHEQEKIREQEEKRQEEEKIR--------EQEKRQEQEAK 384 Query: 138 RAGNLGKNPDVDTSFLPDRD-REEEENRLREELRQEWEAQREKVKDEE 184 K + + + +E+E ++ E+ + WE + E + EE Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEE 432 Score = 36.2 bits (82), Expect = 0.041 Identities = 36/191 (18%), Positives = 88/191 (46%), Gaps = 3/191 (1%) Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKR--FSAHYDAVEAELKS 62 K R+ RA LL +++ Q E + K+ + L++QV++ ++ E ++ Sbjct: 233 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 292 Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSF 122 + + QE +RE+E ++ +++ + ++ +++ +R++E E++ KI L Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEK-EEKMRRQEEMMWEKEEKIRELEE 351 Query: 123 ALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 + + + + E R+ + + R+EE+ R +EE +E E ++ ++ Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEE 411 Query: 183 EEMEVTFSYWD 193 + E W+ Sbjct: 412 KMGEQEEKMWE 422 Score = 36.2 bits (82), Expect = 0.041 Identities = 36/207 (17%), Positives = 94/207 (45%), Gaps = 28/207 (13%) Query: 3 QYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAV---EAE 59 Q + +RE + K RQ E++ +++I E+ + + +++ + + E E Sbjct: 367 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426 Query: 60 LKSSTVGLVTLNDMKARQEALVRERERQLAKRQHL---EEQRL----------------Q 100 ++ + + QE +RE+E ++ +++ + +E+++ Q Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486 Query: 101 QERQREQEQR-RERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE 159 +E+ R QE++ RE+++KI + + ++ E + K + + ++ +E Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE-----EKMQE 541 Query: 160 EEENRLREELRQEWEAQREKVKDEEME 186 +EE R+E + + R + ++E+M+ Sbjct: 542 QEEKMRRQEEKMREQEVRLRQQEEKMQ 568 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 48.5 bits (114), Expect = 8e-06 Identities = 38/114 (33%), Positives = 55/114 (48%), Gaps = 7/114 (6%) Query: 76 RQEALVRERERQLAK---RQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQAD 132 RQ +ERERQ + RQ E + ERQRE++++RERKR+ D + + + Sbjct: 48 RQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRE 107 Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 R G + D +RDRE E R RE RQ QRE+ ++ + E Sbjct: 108 TDRNRERNRKG-GRERDKQTERERDRERERQRQRERERQR---QRERKRETDRE 157 Score = 39.3 bits (90), Expect = 0.005 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 8/117 (6%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133 + R+ ERE + +R E+ Q +R++E+E+++ER R+ + + Q + Sbjct: 23 RQRERENQTERENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRER 82 Query: 134 AEAR-RAGNLGKNPDVDTSFLPDRDREEEENRLREELR---QEWEAQREKVKDEEME 186 R R + D D DR+R+ E +R RE R +E + Q E+ +D E E Sbjct: 83 QRQRERKRQTDRERDKDR----DRERKRETDRNRERNRKGGRERDKQTERERDRERE 135 Score = 38.1 bits (87), Expect = 0.011 Identities = 41/191 (21%), Positives = 80/191 (41%), Gaps = 16/191 (8%) Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60 M + + RE R ++R+RQRE+ +T +++ +R + + Sbjct: 1 MERQRERKRETDRGKETERERDRQRER--------ENQTERENRHRQRDRHRERDRQTDR 52 Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120 + + + R+ RE ERQ +RQ E++ Q +R+R++++ RERKR+ Sbjct: 53 EKERERQKERDRQRQRERETERETERQ-RERQRQRERKRQTDRERDKDRDRERKRETDRN 111 Query: 121 -------SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEW 173 D ++ E R + + DRE + REE ++E Sbjct: 112 RERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKER 171 Query: 174 EAQREKVKDEE 184 + +R+K + E+ Sbjct: 172 KKERKKERKEK 182 Score = 33.5 bits (75), Expect = 0.26 Identities = 30/110 (27%), Positives = 49/110 (44%), Gaps = 16/110 (14%) Query: 82 RERERQLAKRQHLEEQRLQQERQREQEQR--RERKRKISCLSFALDDLDDQADAAEARRA 139 RER+R+ + + E +R +Q + Q +R R R+R + D Q D + R Sbjct: 5 RERKRETDRGKETERERDRQRERENQTERENRHRQRD------RHRERDRQTDREKERE- 57 Query: 140 GNLGKNPDVDTSFLPDRDREEEENRLREELRQ---EWEAQREKVKDEEME 186 + + D +R+ E E R RE RQ + + RE+ KD + E Sbjct: 58 ----RQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRE 103 Score = 29.6 bits (65), Expect = 3.8 Identities = 12/43 (27%), Positives = 27/43 (62%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116 + RQ R+RE +++ E + ++ER++E+++ R+ K+K Sbjct: 142 RERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKKK 184 Score = 28.5 bits (62), Expect = 8.5 Identities = 13/47 (27%), Positives = 31/47 (65%), Gaps = 4/47 (8%) Query: 74 KARQEALVRER----ERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116 + R+ RER ER+ K++ +E++ +++ ++++E+RRE K++ Sbjct: 148 RERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 47.8 bits (112), Expect = 1e-05 Identities = 37/181 (20%), Positives = 92/181 (50%), Gaps = 10/181 (5%) Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67 +RE + + KK Q EQM+ ++++ E+ + +++ + + + K Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351 Query: 68 VTLNDMKAR---QEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFAL 124 + D + R Q+ +RE+E ++ +++ + E Q+E+ +E+E+ RER++K+ + Sbjct: 352 QKMRDQEERMWEQDERLREKEERMREQEKMWE---QEEKMQEEERIREREKKMREEEETM 408 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPD-RDREEEENRLREELRQEWEAQREKVKDE 183 + +++ E + + LP+ +++ E+ +++E+ + WE Q EK++D+ Sbjct: 409 REQEEKMQKQEENMWEQ--EEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWE-QEEKIRDQ 465 Query: 184 E 184 E Sbjct: 466 E 466 Score = 47.0 bits (110), Expect = 2e-05 Identities = 40/186 (21%), Positives = 86/186 (46%), Gaps = 8/186 (4%) Query: 1 MAQYKGTMREAGRAMHLLKKRERQRE-QMEVLKQRIAEETILKSQVDKRFSAHYDAVEAE 59 + + +G MRE M +KR R++E ++ ++ + E+ L+ Q ++ E E Sbjct: 264 LREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE 323 Query: 60 LKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISC 119 K + + RQE + E+E+Q+ R+ ++ R Q+ER EQ++R K + Sbjct: 324 EK-----MREQEEKMWRQEERLWEQEKQM--REQEQKMRDQEERMWEQDERLREKEERMR 376 Query: 120 LSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179 + + +++ E R + +T + +++E + E+ +EW+ QR Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436 Query: 180 VKDEEM 185 + E++ Sbjct: 437 EQKEKL 442 Score = 46.2 bits (108), Expect = 4e-05 Identities = 51/228 (22%), Positives = 105/228 (46%), Gaps = 30/228 (13%) Query: 17 LLKKRERQREQMEVLKQ--RIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMK 74 L +K ER REQ ++ +Q ++ EE + Q K + + K Sbjct: 516 LREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD--------------------QEEK 555 Query: 75 ARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDDLDDQADA 133 R+E +RERE+++ R+ E R Q+E+ +EQE++ RE++ K+ + + +++ Sbjct: 556 MREEERMREREKKM--REEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWE 613 Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFSYWD 193 E + + + + D + E+E +++E+ + WE Q EK++++E ++ Sbjct: 614 QEEK----MWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE-QEEKMREQEEKMREQEEK 668 Query: 194 GSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQLMFIKED 241 G +R ++ Q K Q + E + G E+ M+ +E+ Sbjct: 669 MQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716 Score = 42.4 bits (98), Expect = 6e-04 Identities = 43/188 (22%), Positives = 79/188 (42%), Gaps = 14/188 (7%) Query: 18 LKKRERQREQMEV--LKQRIAEETILKSQVDKR-FSAHYDAVEAELKSSTVGLVTLNDMK 74 L + E+ Q+ V LK+++ L QV E EL+ + + Sbjct: 198 LAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKM 257 Query: 75 ARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAA 134 RQE +RE+E ++ R+ E+ R Q++R REQE+ + K L + ++Q Sbjct: 258 WRQEERLREQEGKM--REQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ 315 Query: 135 EARRAGNLGKNPDVDTSFLPDRDR--------EEEENRLREELRQEWEA-QREKVKDEEM 185 E + K + + +R E+E ++R++ + WE +R + K+E M Sbjct: 316 EEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERM 375 Query: 186 EVTFSYWD 193 W+ Sbjct: 376 REQEKMWE 383 Score = 40.4 bits (93), Expect = 0.002 Identities = 41/181 (22%), Positives = 88/181 (48%), Gaps = 13/181 (7%) Query: 19 KKRERQREQM-EVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77 +K RQ E++ E KQ +E ++ Q ++ + E E + + + K ++ Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQE 390 Query: 78 EALVRERERQLAK-----RQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQAD 132 E +RERE+++ + R+ E+ + Q+E EQE++ +++++ L + ++ Sbjct: 391 EERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-QEKMQ 449 Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEMEVTFSYW 192 E + K D + + ++ +E ++RE+ Q WE Q EK++D+E ++ W Sbjct: 450 EQEEKIWEQEEKIRDQEEMWGQEKKMWRQE-KMREQEDQMWE-QEEKMRDQEQKM----W 503 Query: 193 D 193 D Sbjct: 504 D 504 Score = 40.4 bits (93), Expect = 0.002 Identities = 44/209 (21%), Positives = 92/209 (44%), Gaps = 26/209 (12%) Query: 1 MAQYKGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAEL 60 M + + TMRE M ++ ++E+ E +QR+ E+ + +K E E Sbjct: 401 MREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460 Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHL---EEQRL---------QQERQREQE 108 K + + K ++ +RE+E Q+ +++ +EQ++ Q ER RE+E Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520 Query: 109 QRRERKRKISCLSFALDD-----------LDDQADAAEARRAGNLGKNPDVDTSFLPDRD 157 +R ++K+ + + D + E R K + + +++ Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580 Query: 158 R--EEEENRLREELRQEWEAQREKVKDEE 184 +E+E ++RE+ + WE Q EK++++E Sbjct: 581 EKMQEQEEKMREQEEKMWE-QEEKMQEQE 608 Score = 40.0 bits (92), Expect = 0.003 Identities = 41/195 (21%), Positives = 83/195 (42%), Gaps = 22/195 (11%) Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAE-ETILKSQVDKRFSAHYDAVEAELK----S 62 MRE R KK + E M ++++ E E ++ Q +K + E E K Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615 Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHL-----EEQRLQQERQREQEQR------- 110 + D QE ++ E+E ++ +++ E+ R Q+E+ REQE++ Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEK 675 Query: 111 -RERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREEL 169 RE++ K+ + + +++ E + G K + + E+E R+R++ Sbjct: 676 MREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQK 735 Query: 170 RQEWEAQREKVKDEE 184 E +E++ + E Sbjct: 736 ----EKMQERLPEHE 746 Score = 39.7 bits (91), Expect = 0.004 Identities = 41/180 (22%), Positives = 86/180 (47%), Gaps = 11/180 (6%) Query: 17 LLKKRERQREQMEVLKQ--RIAEETILKSQVDKRFSAHYDAV---EAELKSSTVGLVTLN 71 L +K ER REQ ++ +Q ++ EE ++ + +K+ + + E +++ + Sbjct: 368 LREKEERMREQEKMWEQEEKMQEEERIRER-EKKMREEEETMREQEEKMQKQEENMWEQE 426 Query: 72 DMKARQEALVRERER--QLAKRQHLEEQRLQQERQ-REQEQRRERKRKISCLSFALDDLD 128 + + +Q+ L ++E+ + K Q EE+ +QE + R+QE+ +++K+ + D Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486 Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELR--QEWEAQREKVKDEEME 186 + E R + + D E+E R+RE+ + Q+ E RE+ K +E E Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQE 546 >gi|109150435 ankyrin repeat and zinc finger domain containing 1 [Homo sapiens] Length = 726 Score = 47.8 bits (112), Expect = 1e-05 Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 15/85 (17%) Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDDLDDQ 130 +M+ARQ R+RE++ A+RQ E QQ+RQ+EQE+R RE +R+ + LS D + + Sbjct: 609 EMEARQAT--RKREQKAARRQREE----QQQRQQEQEEREREEQRRFAALS----DREKR 658 Query: 131 ADAAEARRAGNLGKNPDVDTSFLPD 155 A AAE R A LG TS +PD Sbjct: 659 ALAAERRLAAQLG----APTSPIPD 679 >gi|109150425 ankyrin repeat and zinc finger domain containing 1 [Homo sapiens] Length = 726 Score = 47.8 bits (112), Expect = 1e-05 Identities = 37/85 (43%), Positives = 52/85 (61%), Gaps = 15/85 (17%) Query: 72 DMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQR-RERKRKISCLSFALDDLDDQ 130 +M+ARQ R+RE++ A+RQ E QQ+RQ+EQE+R RE +R+ + LS D + + Sbjct: 609 EMEARQAT--RKREQKAARRQREE----QQQRQQEQEEREREEQRRFAALS----DREKR 658 Query: 131 ADAAEARRAGNLGKNPDVDTSFLPD 155 A AAE R A LG TS +PD Sbjct: 659 ALAAERRLAAQLG----APTSPIPD 679 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 18/113 (15%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133 K+R+ R R KR+ E+ ++ER +E+++ +ER+R+ Sbjct: 360 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE----------------- 402 Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 E + GKN D D DR++++E++R RE +E E R+K K++E + Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDRERER-EKEHEKDRDKEKEKEQD 454 Score = 34.7 bits (78), Expect = 0.12 Identities = 23/103 (22%), Positives = 53/103 (51%), Gaps = 8/103 (7%) Query: 84 RERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLG 143 R+++ R+ ++E+ +E+ RE+E+ RE++R+ D D + + + + Sbjct: 374 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK-DREKDKEKD 432 Query: 144 KNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 + + + DRD+E+E+ Q+ E +REK + +E++ Sbjct: 433 REREREKEHEKDRDKEKEK-------EQDKEKEREKDRSKEID 468 Score = 30.0 bits (66), Expect = 2.9 Identities = 21/107 (19%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68 R R + R R++ + +++I E+ +K + ++ E E + Sbjct: 358 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 417 Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115 K R++ ++RER+ K +H +++ ++E+++++E+ RE+ R Sbjct: 418 DKEREKDREKDKEKDREREREK-EHEKDRDKEKEKEQDKEKEREKDR 463 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 47.8 bits (112), Expect = 1e-05 Identities = 31/113 (27%), Positives = 56/113 (49%), Gaps = 18/113 (15%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133 K+R+ R R KR+ E+ ++ER +E+++ +ER+R+ Sbjct: 244 KSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE----------------- 286 Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 E + GKN D D DR++++E++R RE +E E R+K K++E + Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDRERER-EKEHEKDRDKEKEKEQD 338 Score = 34.7 bits (78), Expect = 0.12 Identities = 23/103 (22%), Positives = 53/103 (51%), Gaps = 8/103 (7%) Query: 84 RERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLG 143 R+++ R+ ++E+ +E+ RE+E+ RE++R+ D D + + + + Sbjct: 258 RDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREK-DREKDKEKD 316 Query: 144 KNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 + + + DRD+E+E+ Q+ E +REK + +E++ Sbjct: 317 REREREKEHEKDRDKEKEK-------EQDKEKEREKDRSKEID 352 Score = 30.0 bits (66), Expect = 2.9 Identities = 21/107 (19%), Positives = 52/107 (48%), Gaps = 1/107 (0%) Query: 9 REAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLV 68 R R + R R++ + +++I E+ +K + ++ E E + Sbjct: 242 RSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDR 301 Query: 69 TLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKR 115 K R++ ++RER+ K +H +++ ++E+++++E+ RE+ R Sbjct: 302 DKEREKDREKDKEKDREREREK-EHEKDRDKEKEKEQDKEKEREKDR 347 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 47.4 bits (111), Expect = 2e-05 Identities = 49/182 (26%), Positives = 86/182 (47%), Gaps = 21/182 (11%) Query: 8 MREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGL 67 +RE MH ++E+ REQ E +R EE I + + + A E +++ + Sbjct: 440 IRELEEKMH---EQEKIREQEE---KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 493 Query: 68 VTLNDMKARQEALVRERE--RQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALD 125 + RQE + E+E R+ KRQ EE Q+E+ REQE+ +K KI Sbjct: 494 REQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI-------H 546 Query: 126 DLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKD 182 + +++ E + K D + R++EE+ R E++R++ E Q EK+++ Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKI---REQEEKVWRQEEKIREQEEKIREQEEKIRE 603 Query: 183 EE 184 +E Sbjct: 604 QE 605 Score = 43.1 bits (100), Expect = 3e-04 Identities = 41/179 (22%), Positives = 89/179 (49%), Gaps = 19/179 (10%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 ++ E+ REQ E +++ +E ++ Q + + E +++ + + RQE Sbjct: 379 EQEEKIREQEEKIRE---QEEKMRRQEEMMWEK-----EEKMRRQEEMMWEKEEKMRRQE 430 Query: 79 ALVRERE---RQLAKRQH-------LEEQRLQQERQREQEQRRERKRKISCLSFALDDLD 128 ++ E+E R+L ++ H EE+R ++E+ REQE+R+E++ K+ + + + Sbjct: 431 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490 Query: 129 DQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN-RLREELRQEWEAQREKVKDEEME 186 ++ E + K + + ++ +E+EE R E++R++ E R+K K E E Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549 Score = 41.6 bits (96), Expect = 0.001 Identities = 43/184 (23%), Positives = 83/184 (45%), Gaps = 15/184 (8%) Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKR--FSAHYDAVEAELKS 62 K R+ RA LL +++ Q E + K+ + L++QV++ ++ E ++ Sbjct: 306 KELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWR 365 Query: 63 STVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSF 122 + + QE +RE+E ++ R+ E+ R Q+E E+E++ R+ ++ Sbjct: 366 QEEKIQEWEEKIQEQEEKIREQEEKI--REQEEKMRRQEEMMWEKEEKMRRQEEMMW--- 420 Query: 123 ALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 + RR + + L ++ E+E+ R +EE RQE E RE+ K Sbjct: 421 --------EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKR 472 Query: 183 EEME 186 +E E Sbjct: 473 QEQE 476 Score = 34.3 bits (77), Expect = 0.16 Identities = 34/175 (19%), Positives = 82/175 (46%), Gaps = 24/175 (13%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQE 78 +K RQ E+M +++I E+ + +++ E +++ + +M QE Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQ----EEKIREQEEKIREQEEMTQEQE 612 Query: 79 ALVRERERQLAKRQH-LEEQRLQQERQ----REQEQR-RERKRKISCLSFALDDLDDQAD 132 + E+E ++ +++ ++EQ + RQ REQE++ RE++ KI + + +++ Sbjct: 613 EKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMW 672 Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQ-REKVKDEEME 186 E + + +E+E ++R + + WE + R + ++E+M+ Sbjct: 673 EQEEKMCEQ-------------EEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714 Score = 31.2 bits (69), Expect = 1.3 Identities = 40/181 (22%), Positives = 71/181 (39%), Gaps = 27/181 (14%) Query: 12 GRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDK---RFSAHYDAVEAELKSSTVGLV 68 G A L+ + + L+Q ++ K + D+ + DA+ EL +T+ Sbjct: 219 GEARDLISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDE 278 Query: 69 TLNDMKAR-QEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDL 127 L + A+ QE L Q ++ E+ Q +E KRK+ L Sbjct: 279 ELKEKNAKLQEKL----------------QLVESEKSEIQLNVKELKRKLERAKLLLPQQ 322 Query: 128 DDQADAAEARRAGNLGKN-PDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 QA+A +LGK V + E NRL ++ ++ Q EK+++ E + Sbjct: 323 QLQAEA------DHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEK 376 Query: 187 V 187 + Sbjct: 377 I 377 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 47.0 bits (110), Expect = 2e-05 Identities = 61/240 (25%), Positives = 111/240 (46%), Gaps = 36/240 (15%) Query: 17 LLKKRERQREQMEVLKQ---RIAEETILKSQVDKRFSAHYDAV---EAELKSSTVGLVTL 70 L ++ ER REQ E L++ R+ E+ + ++R + + E L+ L Sbjct: 201 LREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQ 260 Query: 71 NDMKARQEALVRERERQLAKRQHLEEQRL--QQERQREQEQR--------RERKRKISCL 120 + QE +RE+E +L H +E+RL Q+ER REQE+R RE++ ++ Sbjct: 261 EERLCEQEERLREQEERL----HEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQ 316 Query: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEEN-----RLREELRQEWEA 175 L + +++ E + G +V+ +R +EE+E RL EE+ + E Sbjct: 317 EERLREQEERLCEQE-KLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQ 375 Query: 176 QREKVKDEEMEVTFSYWDGSGHRRTVRVRKGNTVQQFLKKALQGLRKDFLELRSAGVEQL 235 +R + +DE + W + R+R+ +++ L+ + L + E RS G E+L Sbjct: 376 ERLRQQDERL------WQQETLQELERLRE---LERMLELGWEALYEQRAEPRS-GFEEL 425 Score = 41.2 bits (95), Expect = 0.001 Identities = 37/138 (26%), Positives = 74/138 (53%), Gaps = 8/138 (5%) Query: 54 DAVEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHL---EEQRL--QQERQREQE 108 ++V +L++ L+ + RQE +RE+E +L +++ +E+RL Q+ER REQE Sbjct: 174 ESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQE 233 Query: 109 QR-RERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE-EEENRLR 166 +R RE++ ++ L + +++ E R + + + +R E+E RLR Sbjct: 234 ERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLR 293 Query: 167 EELRQEWEAQREKVKDEE 184 E+ + E Q E+++++E Sbjct: 294 EQEERLCE-QEERLREQE 310 Score = 33.9 bits (76), Expect = 0.20 Identities = 31/124 (25%), Positives = 60/124 (48%), Gaps = 10/124 (8%) Query: 71 NDMKARQEALVRERERQLAKRQHL------EEQRL--QQERQREQEQR-RERKRKISCLS 121 N ++ E++ R+ + ++ Q L +E+RL Q+ER REQE+R RE++ ++ Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQE 226 Query: 122 FALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDRE-EEENRLREELRQEWEAQREKV 180 L + +++ E R + + + +R E+E RLRE+ + E + Sbjct: 227 ERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLC 286 Query: 181 KDEE 184 + EE Sbjct: 287 EQEE 290 Score = 30.8 bits (68), Expect = 1.7 Identities = 41/180 (22%), Positives = 72/180 (40%), Gaps = 17/180 (9%) Query: 17 LLKKRERQREQMEVL---KQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDM 73 L ++ ER REQ E L ++R+ E+ + ++R + + + + L + Sbjct: 264 LCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQ 323 Query: 74 KAR---------QEALVRERERQLAKRQHLEEQRLQQERQR-----EQEQRRERKRKISC 119 + R QE L+ E E+ L + + EEQ ER+R E+ +ER R+ Sbjct: 324 EERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDE 383 Query: 120 LSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREK 179 + + L + E R LG + P EE N + L+ E + + K Sbjct: 384 RLWQQETLQELERLRELERMLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELK 443 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 47.0 bits (110), Expect = 2e-05 Identities = 39/170 (22%), Positives = 84/170 (49%), Gaps = 15/170 (8%) Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77 LK+ ER R+ ++ ++ + K Q++++F+ + + K+ L + KA++ Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFA------QIDEKTEKAKEERLAEEKAKK 625 Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137 +A ++ E A+R+ EE R + Q+E+E+RR ++ ++Q +A Sbjct: 626 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE------LLQKKKEEEQERLRKAA 679 Query: 138 RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKDEE 184 A L + + + R++E E RE+ R+E E A++E+ +++E Sbjct: 680 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 729 Score = 45.8 bits (107), Expect = 5e-05 Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 43/178 (24%) Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEET--ILKSQVDKRFSAHYDAVEAELKSSTVGL 67 E R + L++ E +R E+L+++ EE + K+ KR + + E Sbjct: 643 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE-------- 694 Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQ---RRERKRKISCLSFAL 124 + R+E RE+ER+ +R+ E Q +QER+REQE+ RE + + L Sbjct: 695 ------QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 + L + L ++ ++EE+ RL E RQ E Q +K K+ Sbjct: 749 EQLQRE----------------------LEEKKKKEEQQRLAE--RQLQEEQEKKAKE 782 Score = 41.6 bits (96), Expect = 0.001 Identities = 47/187 (25%), Positives = 90/187 (48%), Gaps = 37/187 (19%) Query: 24 QREQMEVLKQRIAEETILKSQVDKRFSAHYDA----VEAELKSSTVGLVTLNDMKARQEA 79 QR QM ++ A +++KS + + D VE E + L +++ ++EA Sbjct: 500 QRNQM-LMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQR-------LENLRRKEEA 551 Query: 80 -LVRERERQLAKRQHLEEQRLQQE---------RQREQEQRRERKRKISCLSFALDDLDD 129 +R ++ + KR+ LEE +L++E R+R ++ + E+K++I +D+ + Sbjct: 552 EQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTE 611 Query: 130 QAD-----AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQR-----EK 179 +A +A++ K +V+ R ++EEE R L+QE E +R +K Sbjct: 612 KAKEERLAEEKAKKKAAAKKMEEVEA-----RRKQEEEARRLRWLQQEEEERRHQELLQK 666 Query: 180 VKDEEME 186 K+EE E Sbjct: 667 KKEEEQE 673 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 47.0 bits (110), Expect = 2e-05 Identities = 39/170 (22%), Positives = 84/170 (49%), Gaps = 15/170 (8%) Query: 18 LKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQ 77 LK+ ER R+ ++ ++ + K Q++++F+ + + K+ L + KA++ Sbjct: 568 LKREERLRKVLQARERVEQMKEEKKKQIEQKFA------QIDEKTEKAKEERLAEEKAKK 621 Query: 78 EALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEAR 137 +A ++ E A+R+ EE R + Q+E+E+RR ++ ++Q +A Sbjct: 622 KAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQE------LLQKKKEEEQERLRKAA 675 Query: 138 RAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWE---AQREKVKDEE 184 A L + + + R++E E RE+ R+E E A++E+ +++E Sbjct: 676 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 725 Score = 45.8 bits (107), Expect = 5e-05 Identities = 45/178 (25%), Positives = 77/178 (43%), Gaps = 43/178 (24%) Query: 10 EAGRAMHLLKKRERQREQMEVLKQRIAEET--ILKSQVDKRFSAHYDAVEAELKSSTVGL 67 E R + L++ E +R E+L+++ EE + K+ KR + + E Sbjct: 639 EEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE-------- 690 Query: 68 VTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQ---RRERKRKISCLSFAL 124 + R+E RE+ER+ +R+ E Q +QER+REQE+ RE + + L Sbjct: 691 ------QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744 Query: 125 DDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKD 182 + L + L ++ ++EE+ RL E RQ E Q +K K+ Sbjct: 745 EQLQRE----------------------LEEKKKKEEQQRLAE--RQLQEEQEKKAKE 778 Score = 41.6 bits (96), Expect = 0.001 Identities = 46/178 (25%), Positives = 83/178 (46%), Gaps = 23/178 (12%) Query: 24 QREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVGLVTLNDMKARQEA-LVR 82 QR QM ++ A +++KS + + D E E + L +++ ++EA +R Sbjct: 500 QRNQM-LMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQR-------LENLRRKEEAEQLR 551 Query: 83 ERERQLAKRQHLEEQRLQ-QERQREQEQRRER-----KRKISCLSFALDDLDDQADAAEA 136 ++ + KR+ LEE +L+ +ER R+ Q RER + K + +D++ + A+ Sbjct: 552 RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKE 611 Query: 137 RRAGNLGKNPDVDTSFLPD---RDREEEENRLREELRQEWEAQR-----EKVKDEEME 186 R + + R ++EEE R L+QE E +R +K K+EE E Sbjct: 612 ERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE 669 Score = 28.9 bits (63), Expect = 6.5 Identities = 31/151 (20%), Positives = 62/151 (41%), Gaps = 13/151 (8%) Query: 82 RERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGN 141 +E+ERQ + +E+ Q RQ+ +E +R R ++ + L A E Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLK--REERLRKVLQARERVEQMK 588 Query: 142 LGKNPDVDTSF--LPDRDREEEENRLREE---------LRQEWEAQREKVKDEEMEVTFS 190 K ++ F + ++ + +E RL EE +E EA+R++ ++ Sbjct: 589 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 648 Query: 191 YWDGSGHRRTVRVRKGNTVQQFLKKALQGLR 221 + + + +K Q+ L+KA + R Sbjct: 649 QEEEERRHQELLQKKKEEEQERLRKAAEAKR 679 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 46.6 bits (109), Expect = 3e-05 Identities = 39/180 (21%), Positives = 82/180 (45%), Gaps = 11/180 (6%) Query: 7 TMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSSTVG 66 T RE+ R ++RER++ + E K+R E + + K+ + + Sbjct: 30 TQRESERKK---ERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR 86 Query: 67 LVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDD 126 + +++ ++RER+ R+ ++++ ++ER+RE +QRRERKRK + Sbjct: 87 KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKE 146 Query: 127 LDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 + + + R K +R+++ E NR + +E + +RE+ K+ + E Sbjct: 147 RKREKERGKRERKRKKRKK--------EEREKKRERNRKERKKERERKERRERKKERKKE 198 Score = 34.3 bits (77), Expect = 0.16 Identities = 23/112 (20%), Positives = 52/112 (46%), Gaps = 8/112 (7%) Query: 5 KGTMREAGRAMHLLKKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAELKSST 64 K ++ GR KK ++RE+ ++ + K + K + + E K Sbjct: 103 KRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKK 162 Query: 65 VGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRK 116 K + RER R+ K++ ++R +++++R++E+R++++RK Sbjct: 163 --------RKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206 Score = 32.0 bits (71), Expect = 0.77 Identities = 22/102 (21%), Positives = 44/102 (43%), Gaps = 12/102 (11%) Query: 85 ERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAAEARRAGNLGK 144 E Q+ H+ + Q+E +R++E+R KRK + + R G K Sbjct: 16 ELQMVSCSHISKPCTQRESERKKERREREKRK------------REREKERKRERGKKEK 63 Query: 145 NPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 +R+R+ +E + + R+E E ++ K + ++ E Sbjct: 64 KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRE 105 Score = 29.3 bits (64), Expect = 5.0 Identities = 25/138 (18%), Positives = 60/138 (43%), Gaps = 7/138 (5%) Query: 56 VEAELKSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQ-------QERQREQE 108 + EL+ + ++ + E RER+ KR+ +E++ + + ++RE+ Sbjct: 13 LNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERG 72 Query: 109 QRRERKRKISCLSFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREE 168 + RERKRK ++ + ++ + + +R E EN+ R E Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132 Query: 169 LRQEWEAQREKVKDEEME 186 +++ ++++ K+ + E Sbjct: 133 RKRKKRRKKKRRKERKRE 150 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 46.6 bits (109), Expect = 3e-05 Identities = 33/118 (27%), Positives = 56/118 (47%), Gaps = 24/118 (20%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADA 133 + R+ +RER AK E++ +++RQR++E+ RER R D+ Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDR-------------DRERE 65 Query: 134 AEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ-----EWEAQREKVKDEEME 186 + R G + + DRDR+ E R R++ R+ E + +R+K K+ EME Sbjct: 66 KQTDREGERQRERE------RDRDRQRETERERDKERETDRHTETDRERQKQKEREME 117 Score = 42.4 bits (98), Expect = 6e-04 Identities = 43/164 (26%), Positives = 67/164 (40%), Gaps = 21/164 (12%) Query: 5 KGTMREAGRAMHLLKKRERQRE-QMEVLKQRIAE---ETILKSQVDKRFSAHYDAVEAEL 60 K T RE R + R+RQRE + E K+R + ET + Q K Sbjct: 66 KQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125 Query: 61 KSSTVGLVTLNDMKARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCL 120 K +G D + RERERQ + + +R ++R RE+E+ R+R+R Sbjct: 126 KQKEMGRERQTDRETD-----RERERQAERERETGRERKTEDRHRERERERKRER----- 175 Query: 121 SFALDDLDDQADAAEARRAGNLGKNPDVDTSFLPDRDREEEENR 164 + + + E R ++ + +T DR RE E R Sbjct: 176 -------ERKRETKERERHTDMERERQRETDRKRDRQRESERER 212 Score = 37.7 bits (86), Expect = 0.014 Identities = 29/98 (29%), Positives = 47/98 (47%), Gaps = 7/98 (7%) Query: 90 KRQHLEEQRLQQERQREQEQRRERKR-KISCLSFALDDLDDQADAAEARRAGNLGKNPDV 148 + H E + + ++R+R +E RER R K S + D Q D R N ++ D Sbjct: 8 RHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRD-----RERNRERDRDR 62 Query: 149 DTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 + DR+ E + R R+ RQ E +RE+ K+ E + Sbjct: 63 EREKQTDREGERQRERERDRDRQR-ETERERDKERETD 99 Score = 37.4 bits (85), Expect = 0.018 Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 11/115 (9%) Query: 76 RQEALVRERERQLAKRQHLE---EQRLQQERQREQEQRRER-KRKISCLSFALDDLDDQA 131 RQ RER+++ +H E E++ Q+ER+ E+ + RER K+K D D+ Sbjct: 84 RQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRE 143 Query: 132 DAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQEWEAQREKVKDEEME 186 +A R G+ + DR E R R+ R+ +E+ + +ME Sbjct: 144 RERQAERERETGRERKTE-------DRHRERERERKRERERKRETKERERHTDME 191 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 46.6 bits (109), Expect = 3e-05 Identities = 37/170 (21%), Positives = 87/170 (51%), Gaps = 21/170 (12%) Query: 19 KKRERQREQMEVLKQRIAEETILKSQVDKRFSAHYDAVEAE-LKSSTVGLVTLNDMKARQ 77 K+R RQ+ ++ +R + + + ++R A AE LK L L + + Sbjct: 446 KQRRRQQSEISAAVERARKR---REEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPE 502 Query: 78 EALVRERERQLAKRQHLE---EQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAA 134 E RERE++ + + LE EQ ++ER++++E+++E+++++ +Q Sbjct: 503 EIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELE---------KEQEKQR 553 Query: 135 EARRAGNLGKNPDVDTSFLPDRDREEEENRLREELRQ-EWEAQREKVKDE 183 E + K +++ +++E+E +++E+ ++ E E +REK++++ Sbjct: 554 EMEKERKQEKEKELER----QKEKEKELQKMKEQEKECELEKEREKLEEK 599 Score = 44.3 bits (103), Expect = 1e-04 Identities = 35/113 (30%), Positives = 61/113 (53%), Gaps = 16/113 (14%) Query: 75 ARQEALVRERERQLAKRQHLEEQRLQQERQREQEQRRERKRKISCLSFALDDLDDQADAA 134 A ++ + ++R RQ ++ E+ ++R+ E+E+R E +RK +C L LD+ Sbjct: 439 ADEDEIWKQRRRQQSEISAAVERA--RKRREEEERRMEEQRKAACAE-KLKRLDE----- 490 Query: 135 EARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186 + G L K P + R+RE E+ R RE EL +E E +REK ++++ E Sbjct: 491 ---KLGILEKQPSPEEI----REREREKEREREKELEKEQEQEREKEREKDRE 536 Score = 42.7 bits (99), Expect = 4e-04 Identities = 34/115 (29%), Positives = 58/115 (50%), Gaps = 24/115 (20%) Query: 85 ERQLAKRQHLEEQRLQQE------------RQREQEQRRERKRKISCLSFALDDLDDQAD 132 ++Q+A + +QR +Q+ R+ E+E+R E +RK +C L LD+ Sbjct: 435 KQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAE-KLKRLDE--- 490 Query: 133 AAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-ELRQEWEAQREKVKDEEME 186 + G L K P + + +R+RE+E R +E E QE E ++E+ KD E + Sbjct: 491 -----KLGILEKQPSPEE--IREREREKEREREKELEKEQEQEREKEREKDRERQ 538 Score = 40.0 bits (92), Expect = 0.003 Identities = 27/121 (22%), Positives = 64/121 (52%), Gaps = 8/121 (6%) Query: 74 KARQEALVRERERQLAKRQHLEEQRLQQERQR---EQEQRRERKRKISCLSFALDDLDDQ 130 + RQ++ + + KR+ EE+R++++R+ E+ +R + K I + +++ ++ Sbjct: 448 RRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRER 507 Query: 131 ADAAEARRAGNLGKNPDVDTSFLPDRDREEEENRLRE-----ELRQEWEAQREKVKDEEM 185 E R L K + + ++DRE ++ + +E E ++E E +R++ K++E+ Sbjct: 508 EREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKEL 567 Query: 186 E 186 E Sbjct: 568 E 568 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.373 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,656,877 Number of Sequences: 37866 Number of extensions: 524855 Number of successful extensions: 14293 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 297 Number of HSP's successfully gapped in prelim test: 694 Number of HSP's that attempted gapping in prelim test: 5441 Number of HSP's gapped (non-prelim): 4084 length of query: 325 length of database: 18,247,518 effective HSP length: 102 effective length of query: 223 effective length of database: 14,385,186 effective search space: 3207896478 effective search space used: 3207896478 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.