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Search of human proteins with 68299795
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
(1710 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 3470 0.0
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 1969 0.0
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa... 569 e-162
gi|52630326 chromodomain helicase DNA binding protein 3 isoform ... 566 e-161
gi|52630322 chromodomain helicase DNA binding protein 3 isoform ... 566 e-161
gi|158420731 chromodomain helicase DNA binding protein 3 isoform... 566 e-161
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 543 e-154
gi|54112403 chromodomain helicase DNA binding protein 7 [Homo sa... 518 e-146
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 516 e-146
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 515 e-145
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 496 e-140
gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 470 e-132
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r... 446 e-125
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re... 438 e-122
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re... 431 e-120
gi|148612870 chromodomain helicase DNA binding protein 1-like [H... 410 e-114
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 403 e-112
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 403 e-112
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 397 e-110
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 397 e-110
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 396 e-109
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 396 e-109
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 392 e-108
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 392 e-108
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 384 e-106
gi|190358536 SWI/SNF-related, matrix-associated actin-dependent ... 298 3e-80
gi|190358532 SWI/SNF-related, matrix-associated actin-dependent ... 298 3e-80
gi|190358534 SWI/SNF-related, matrix-associated actin-dependent ... 297 5e-80
gi|4557565 excision repair cross-complementing rodent repair def... 256 1e-67
gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto... 248 3e-65
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 3470 bits (8997), Expect = 0.0
Identities = 1710/1710 (100%), Positives = 1710/1710 (100%)
Query: 1 MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGS 60
MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGS
Sbjct: 1 MNGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGS 60
Query: 61 QSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNS 120
QSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNS
Sbjct: 61 QSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNS 120
Query: 121 GSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETES 180
GSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETES
Sbjct: 121 GSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETES 180
Query: 181 DYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNV 240
DYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNV
Sbjct: 181 DYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNV 240
Query: 241 SYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEAD 300
SYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEAD
Sbjct: 241 SYKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEAD 300
Query: 301 GDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETK 360
GDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETK
Sbjct: 301 GDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETK 360
Query: 361 RWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSE 420
RWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSE
Sbjct: 361 RWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSE 420
Query: 421 CSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLE 480
CSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLE
Sbjct: 421 CSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLE 480
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS
Sbjct: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK
Sbjct: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFI 660
AFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFI
Sbjct: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFI 660
Query: 661 MPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSA 720
MPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSA
Sbjct: 661 MPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSA 720
Query: 721 LQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEAL 780
LQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEAL
Sbjct: 721 LQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEAL 780
Query: 781 QHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKG 840
QHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKG
Sbjct: 781 QHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKG 840
Query: 841 ELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHR 900
ELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHR
Sbjct: 841 ELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHR 900
Query: 901 IGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPF 960
IGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPF
Sbjct: 901 IGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPF 960
Query: 961 NKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFK 1020
NKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFK
Sbjct: 961 NKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFK 1020
Query: 1021 VANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQI 1080
VANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQI
Sbjct: 1021 VANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQI 1080
Query: 1081 SFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKK 1140
SFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKK
Sbjct: 1081 SFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKK 1140
Query: 1141 FGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGP 1200
FGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGP
Sbjct: 1141 FGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALKDSSSGTERTGGRLGKVKGP 1200
Query: 1201 TFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSN 1260
TFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSN
Sbjct: 1201 TFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSN 1260
Query: 1261 LLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKK 1320
LLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKK
Sbjct: 1261 LLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKK 1320
Query: 1321 EALSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRER 1380
EALSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRER
Sbjct: 1321 EALSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRER 1380
Query: 1381 SKKSSVSDAPVHITASGEPVPISEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSE 1440
SKKSSVSDAPVHITASGEPVPISEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSE
Sbjct: 1381 SKKSSVSDAPVHITASGEPVPISEESEELDQKTFSICKERMRPVKAALKQLDRPEKGLSE 1440
Query: 1441 REQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHA 1500
REQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHA
Sbjct: 1441 REQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDARKLHKLYKHA 1500
Query: 1501 IKKRQESQQNSDQNSNLNPHVIRNPDVERLKENTNHDDSSRDSYSSDRHLTQYHDHHKDR 1560
IKKRQESQQNSDQNSNLNPHVIRNPDVERLKENTNHDDSSRDSYSSDRHLTQYHDHHKDR
Sbjct: 1501 IKKRQESQQNSDQNSNLNPHVIRNPDVERLKENTNHDDSSRDSYSSDRHLTQYHDHHKDR 1560
Query: 1561 HQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLE 1620
HQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLE
Sbjct: 1561 HQGDSYKKSDSRKRPYSSFSNGKDHRDWDHYKQDSRYYSDREKHRKLDDHRSRDHRSNLE 1620
Query: 1621 GSLKDRSHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLD 1680
GSLKDRSHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLD
Sbjct: 1621 GSLKDRSHSDHRSHSDHRLHSDHRSSSEYTHHKSSRDYRYHSDWQMDHRASSSGPRSPLD 1680
Query: 1681 QRSPYGSRSPFEHSVEHKSTPEHTWSSRKT 1710
QRSPYGSRSPFEHSVEHKSTPEHTWSSRKT
Sbjct: 1681 QRSPYGSRSPFEHSVEHKSTPEHTWSSRKT 1710
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 1969 bits (5101), Expect = 0.0
Identities = 1050/1843 (56%), Positives = 1289/1843 (69%), Gaps = 168/1843 (9%)
Query: 2 NGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQ 61
+ HS E + S SQS+ + GS GSG GS S SSS+ S SQS S+S+S +GS+
Sbjct: 20 SSHSASEEA-SGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQS-ESESES---AGSK 74
Query: 62 SESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSG 121
S+ ++E K D + W+ P + V+RS + Q S
Sbjct: 75 SQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRS-----------NRSRQEPSRFN 123
Query: 122 SEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESD 181
+E++SS +S +R+ K E W+ S + G+ +ESE E++K
Sbjct: 124 IKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV-- 181
Query: 182 YEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVS 241
P+ V + + + K++ GK+ K+Q DSS+EDDD+++ KR +RR+A NVS
Sbjct: 182 --PRRTVPKPRVKKQPKTQRGKR-----KKQ-DSSDEDDDDDEAP--KRQTRRRAAKNVS 231
Query: 242 YKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADG 301
YKED++ +TDSDDL+E+ GE V + +++ ETIE+ +D R+G+KGATGA+TT+YA+EA+G
Sbjct: 232 YKEDDDFETDSDDLIEMTGEGVDE-QQDNSETIEKVLDSRLGKKGATGASTTVYAIEANG 290
Query: 302 DPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKR 361
DP+ F+ K+ GEIQYLIKWKGWS+IH+TWE+EE+L+QQ V+G+KKL+N+KKK+ E K+
Sbjct: 291 DPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQ 350
Query: 362 WLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIA---------------HSNQKSAAGY 406
WL SPEDVEY+NCQQEL +L+KQYQIVER+IA HS + + +
Sbjct: 351 WLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNE 410
Query: 407 PDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVAL 466
P+Y CKW GLPYSECSWED ALI KKFQ CID + SRN SKT P ++CK LKQRPRFVAL
Sbjct: 411 PEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVAL 470
Query: 467 KKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHE 526
KKQP+Y+GG E LELRDYQL GLNWLAHSWCK NS ILADEMGLGKTIQTISFL+YLFH+
Sbjct: 471 KKQPAYLGG-ENLELRDYQLEGLNWLAHSWCKNNSVILADEMGLGKTIQTISFLSYLFHQ 529
Query: 527 HQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKF 586
HQLYGPFL+VVPLSTLTSWQRE + WA ++N VVY+GD+ SRN IR +EW H QTKRLKF
Sbjct: 530 HQLYGPFLIVVPLSTLTSWQREFEIWAPEINVVVYIGDLMSRNTIREYEWIHSQTKRLKF 589
Query: 587 NILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPL 646
N L+TTYEILLKDK LG +NWAF+GVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPL
Sbjct: 590 NALITTYEILLKDKTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPL 649
Query: 647 QNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKSL 706
QNSLKELWSLLHFIMPEKF WEDFEE+HGKGRE GY SLHK LEPFLLRRVKKDVEKSL
Sbjct: 650 QNSLKELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKSL 709
Query: 707 PAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLIK 766
PAKVEQILR+EMSALQKQYYKWILTRNYKAL+KG++GSTSGFLNI+MELKKCCNHCYLIK
Sbjct: 710 PAKVEQILRVEMSALQKQYYKWILTRNYKALAKGTRGSTSGFLNIVMELKKCCNHCYLIK 769
Query: 767 PPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKY 826
PP+ NE N QE L LIRSSGKLILLDKLL RLRERGNRVLIFSQMVRMLDILAEYL
Sbjct: 770 PPEENERENGQEILLSLIRSSGKLILLDKLLTRLRERGNRVLIFSQMVRMLDILAEYLTI 829
Query: 827 RQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDW 886
+ +PFQRLDGSIKGE+RKQALDHFNA+GSEDFCFLLSTRAGGLGINLASADTVVIFDSDW
Sbjct: 830 KHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGLGINLASADTVVIFDSDW 889
Query: 887 NPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKT 946
NPQNDLQAQARAHRIGQKKQVNIYRLVTKG+VEE+I+ERAKKKMVLDHLVIQRMDTTG+T
Sbjct: 890 NPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKKMVLDHLVIQRMDTTGRT 949
Query: 947 VLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEP 1006
+L S S+S PFNKEEL+AILKFGAE+LFKE EGEE EPQEMDIDEIL+ AET ENE
Sbjct: 950 ILENNSGRSNSNPFNKEELTAILKFGAEDLFKELEGEESEPQEMDIDEILRLAETRENEV 1009
Query: 1007 GPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEE 1066
+ DELLSQFKVANF+ M ED+ ELE ER K+W+EIIPE+QR+++EEEERQKELEE
Sbjct: 1010 S-TSATDELLSQFKVANFATM-EDEEELE-ERPHKDWDEIIPEEQRKKVEEEERQKELEE 1066
Query: 1067 IYMLPRMRNCAKQISFNGSEG-----RRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRE 1121
IYMLPR+R+ K+ N S+ R+++ S S+++ + K+PK+RGRPR++ ++
Sbjct: 1067 IYMLPRIRSSTKKAQTNDSDSDTESKRQAQRSSASESETEDSDDDKKPKRRGRPRSVRKD 1126
Query: 1122 NIKGFSDAEIRRFIKSYKKFGGPLERLDAIARDAELVDKSETDLRRLGELVHNGCIKALK 1181
++GF+DAEIRRFIK+YKKFG PLERL+ IARDAELVDKS DL+RLGEL+HN C+ A++
Sbjct: 1127 LVEGFTDAEIRRFIKAYKKFGLPLERLECIARDAELVDKSVADLKRLGELIHNSCVSAMQ 1186
Query: 1182 DSSSGTERT---GGRLGKVKGPTFRISGVQVNAKLVISHEEELIPLHKSIPSDPEERKQY 1238
+ + G GK +GPT +ISGVQVN K +I HEEE LHKSIP DPEE+K+Y
Sbjct: 1187 EYEEQLKENASEGKGPGKRRGPTIKISGVQVNVKSIIQHEEEFEMLHKSIPVDPEEKKKY 1246
Query: 1239 TIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQ 1298
+ C KAAHFD++WG EDDS LL+GIYE+GYG+WE+IK DP+L LT KILP + DKKPQ
Sbjct: 1247 CLTCRVKAAHFDVEWGVEDDSRLLLGIYEHGYGNWELIKTDPELKLTDKILPVETDKKPQ 1306
Query: 1299 AKQLQTRADYLIKLLSRDLAKKEALSGAGSS--KRRKARAKKNKAMKSIKVKEEIKSDS- 1355
KQLQTRADYL+KLL + L KK A++G + K+RK R KK + +K + I+ S
Sbjct: 1307 GKQLQTRADYLLKLLRKGLEKKGAVTGGEEAKLKKRKPRVKKENKVPRLKEEHGIELSSP 1366
Query: 1356 --SPLPSEKSDEDDDKLSES---------------------------------------- 1373
S PSE+ + DD L +S
Sbjct: 1367 RHSDNPSEEGEVKDDGLEKSPMKKKQKKKENKENKEKQMSSRKDKEGDKERKKSKDKKEK 1426
Query: 1374 -KSDGRERSKKSSVSDAPVHITASGEPVPISE-ESEELDQKTFSICKERMRPVKAALKQL 1431
KS + S KS S PVHITA EPVPI E E ++LDQ+TFSICKERMRPVK ALKQL
Sbjct: 1427 PKSGDAKSSSKSKRSQGPVHITAGSEPVPIGEDEDDDLDQETFSICKERMRPVKKALKQL 1486
Query: 1432 DRPEKGLSEREQLEHTRQCLIKIGDHITECLKEYTNPEQIKQWRKNLWIFVSKFTEFDAR 1491
D+P+KGL+ +EQLEHTR CL+KIGD I ECLK Y++ E IK WR+NLWIFVSKFTEFDAR
Sbjct: 1487 DKPDKGLNVQEQLEHTRNCLLKIGDRIAECLKAYSDQEHIKLWRRNLWIFVSKFTEFDAR 1546
Query: 1492 KLHKLYKHAIKKR----QESQQNSDQNSNLNPHVIRNPDVER----LKENTNHDDSSRDS 1543
KLHKLYK A KKR +E ++ D P R + +T+H+ +
Sbjct: 1547 KLHKLYKMAHKKRSQEEEEQKKKDDVTGGKKPFRPEASGSSRDSLISQSHTSHNLHPQKP 1606
Query: 1544 YSSDRHLTQYHDHHKD-------RHQGDSYKKSDSRKRPYSSFSNGKDHRDWD---HYKQ 1593
+ H Q H H +D RH ++ + R+R + ++ G ++ W H++
Sbjct: 1607 HLPASHGPQMHGHPRDNYNHPNKRHFSNADRGDWQRERKF-NYGGGNNNPPWGSDRHHQY 1665
Query: 1594 DSRYYSDRE--KHRKLDDHRSRDHRSN-------LEGSLKDRSHSDHRSHSDHRLH---- 1640
+ +Y D R +D HRS +R N + DR H HR + D H
Sbjct: 1666 EQHWYKDHHYGDRRHMDAHRSGSYRPNNMSRKRPYDQYSSDRDHRGHRDYYDRHHHDSKR 1725
Query: 1641 -------------------SDHRSSSEYTHHKSSRDYR-YHSDWQMDHR-------ASSS 1673
SDHR + Y S YR +H+D +++ + S
Sbjct: 1726 RRSDEFRPQNYHQQDFRRMSDHRPAMGYHGQGPSDHYRSFHTDKLGEYKQPLPPLHPAVS 1785
Query: 1674 GPRSPLDQRSPYGSRSPFEH------SVEHKSTPEHTWSSRKT 1710
PRSP Q+SP+ S+SP +H S+E K+ P++ W+ RKT
Sbjct: 1786 DPRSPPSQKSPHDSKSPLDHRSPLERSLEQKNNPDYNWNVRKT 1828
>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
sapiens]
Length = 1912
Score = 569 bits (1466), Expect = e-162
Identities = 359/936 (38%), Positives = 524/936 (55%), Gaps = 116/936 (12%)
Query: 300 DGDPNAGFEKNKEPG-EIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKK--- 355
D DPN K E E Q+ +KW+G S+ H +W +E L+ + NY++K
Sbjct: 524 DADPNTPSPKPLEGRPERQFFVKWQGMSYWHCSWVSELQLE---LHCQVMFRNYQRKNDM 580
Query: 356 ----------DQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAG 405
D+E R KN P+ E ++ + ++ ++ RI+ HS K G
Sbjct: 581 DEPPSGDFGGDEEKSRKRKNKDPKFAEME--ERFYRYGIKPEWMMIHRILNHSVDKK--G 636
Query: 406 YPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQ----SKTTPFKDCKVLK--- 458
+ Y KW+ LPY + SWE + + + Y++ + + P K K +K
Sbjct: 637 HVHYLIKWRDLPYDQASWESEDVEIQDYDLFKQSYWNHRELMRGEEGRPGKKLKKVKLRK 696
Query: 459 -QRPR-------FVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGL 510
+RP V ++QP Y+ G L YQ+ GLNWL SW +G ILADEMGL
Sbjct: 697 LERPPETPTVDPTVKYERQPEYLDATGGT-LHPYQMEGLNWLRFSWAQGTDTILADEMGL 755
Query: 511 GKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNM 570
GKT+QT FL L+ E GPFL+ PLST+ +W+RE + WA M V Y+GD +SR +
Sbjct: 756 GKTVQTAVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDMYVVTYVGDKDSRAI 815
Query: 571 IRTHEWTHHQTK--------------RLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEA 616
IR +E++ +KF++LLT+YE++ D A LG ++WA + VDEA
Sbjct: 816 IRENEFSFEDNAIRGGKKASRMKKEASVKFHVLLTSYELITIDMAILGSIDWACLIVDEA 875
Query: 617 HRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHG 676
HRLKN+ S ++ L + H+LL+TGTPLQN+L+EL+ LL+F+ PE+F + E F EE
Sbjct: 876 HRLKNNQSKFFRVLNGYSLQHKLLLTGTPLQNNLEELFHLLNFLTPERFHNLEGFLEEFA 935
Query: 677 K-GREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYK 735
+E LH L P +LRR+K DV K++P+K E I+R+E+S +QK+YYK+ILTRN++
Sbjct: 936 DIAKEDQIKKLHDMLGPHMLRRLKADVFKNMPSKTELIVRVELSPMQKKYYKYILTRNFE 995
Query: 736 ALSKGSKGSTSGFLNIMMELKKCCNHCYLIK------PPDNNEFYNKQEALQHLIRSSGK 789
AL+ G+ LN++M+LKKCCNH YL P N Y+ LIR+SGK
Sbjct: 996 ALNARGGGNQVSLLNVVMDLKKCCNHPYLFPVAAMEAPKMPNGMYDGSA----LIRASGK 1051
Query: 790 LILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDH 849
L+LL K+L L+E G+RVLIFSQM +MLD+L ++L++ + ++R+DG I G +R++A+D
Sbjct: 1052 LLLLQKMLKNLKEGGHRVLIFSQMTKMLDLLEDFLEHEGYKYERIDGGITGNMRQEAIDR 1111
Query: 850 FNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNI 909
FNA G++ FCFLLSTRAGGLGINLA+ADTV+I+DSDWNP ND+QA +RAHRIGQ K+V I
Sbjct: 1112 FNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMI 1171
Query: 910 YRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAIL 969
YR VT+ SVEE I + AKKKM+L HLV++ S + +K+EL IL
Sbjct: 1172 YRFVTRASVEERITQVAKKKMMLTHLVVR------------PGLGSKTGSMSKQELDDIL 1219
Query: 970 KFGAEELFKE---------PEGEEQEPQEMD---IDEILKRAETHENEPGPLTVGDELLS 1017
KFG EELFK+ EGE+ D I+ +L R + E E L +E LS
Sbjct: 1220 KFGTEELFKDEATDGGGDNKEGEDSSVIHYDDKAIERLLDRNQ-DETEDTELQGMNEYLS 1278
Query: 1018 QFKVANFSNMDED-DIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYM-LPRMRN 1075
FKVA + +E+ E E ER EE + D +L +++ E++ L + +
Sbjct: 1279 SFKVAQYVVREEEMGEEEEVEREIIKQEESVDPDYWEKLLRHHYEQQQEDLARNLGKGKR 1338
Query: 1076 CAKQISFN-GSEGRRSRSRRYSGSDSD---SISEG-----------KRPKKRG----RPR 1116
KQ+++N GS+ R S + SD + EG +RP ++G + +
Sbjct: 1339 IRKQVNYNDGSQEDRDWQDDQSDNQSDYSVASEEGDEDFDERSEAPRRPSRKGLRNDKDK 1398
Query: 1117 TIP--------RENIKGFSDAEIRRFIKSYKKFGGP 1144
+P + GF+ + + F+ + ++G P
Sbjct: 1399 PLPPLLARVGGNIEVLGFNARQRKAFLNAIMRYGMP 1434
Score = 39.3 bits (90), Expect = 0.033
Identities = 29/96 (30%), Positives = 42/96 (43%), Gaps = 11/96 (11%)
Query: 140 KRKKHKDEDWQMSGS-GSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSR-KPQNRS 197
K K+ K E + G S G + EEE D SDY P K K + P+
Sbjct: 67 KSKRQKKERMLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEK 126
Query: 198 KSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSR 233
KSK+ +K + EE+DD++D K S++
Sbjct: 127 KSKSKRK---------EEEEEEDDDDDSKEPKSSAQ 153
Score = 32.3 bits (72), Expect = 4.1
Identities = 33/163 (20%), Positives = 67/163 (41%), Gaps = 28/163 (17%)
Query: 143 KHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNG 202
+ +D D ++ S P ++ + EE+ ++ + + +PK + P+++ + K
Sbjct: 16 EEEDMDALLNNSLPPPHPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKER 75
Query: 203 KKIL-------GQKKRQIDSSEE-----DDDEEDYDNDKRSS-----RRQATVNVSYKED 245
+ G+ ++ EE D + DY K+ +++ KE+
Sbjct: 76 MLLCRQLGDSSGEGPEFVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRKEE 135
Query: 246 EEMKTDSDD---------LLEVCG-EDVPQP-EEEEFETIERF 277
EE + D DD LLE G ED+ EE++ T+ +
Sbjct: 136 EEEEDDDDDSKEPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNY 178
Score = 31.2 bits (69), Expect = 9.0
Identities = 26/114 (22%), Positives = 52/114 (45%), Gaps = 6/114 (5%)
Query: 1253 WGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYL--- 1309
W + D LL GI +GY W+ I+ DP ++ ++ + ++ L+ + +L
Sbjct: 1729 WHRRHDYWLLAGIINHGYARWQDIQNDPRYAILNEPFKGEMNR---GNFLEIKNKFLARR 1785
Query: 1310 IKLLSRDLAKKEALSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSEKS 1363
KLL + L +E L A + + + A+ + + E ++S S++S
Sbjct: 1786 FKLLEQALVIEEQLRRAAYLNMSEDPSHPSMALNTRFAEVECLAESHQHLSKES 1839
>gi|52630326 chromodomain helicase DNA binding protein 3 isoform 1
[Homo sapiens]
Length = 2000
Score = 566 bits (1458), Expect = e-161
Identities = 358/927 (38%), Positives = 527/927 (56%), Gaps = 105/927 (11%)
Query: 298 EADGDPNAGFEKNKEP-GEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKD 356
+ADG+P+ + + E ++ +KW G S+ H +W E L+ + + NY++K+
Sbjct: 529 QADGNPDVPPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLE---IFHLVMYRNYQRKN 585
Query: 357 -----------------QETKRWLKNASPEDVE--YYNCQQELTDDLHKQYQIVERIIAH 397
+ KR +K+ ++E YY + ++ V RII H
Sbjct: 586 DMDEPPPLDYGSGEDDGKSDKRKVKDPHYAEMEEKYYRF------GIKPEWMTVHRIINH 639
Query: 398 SNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQ--SKTTPFKDCK 455
S K G Y KW+ LPY + +WE+ + +++ Y+ + P + K
Sbjct: 640 SVDKK--GNYHYLVKWRDLPYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRK 697
Query: 456 VLKQRPRF--------------VALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNS 501
K++ V + QP +I G L YQL GLNWL SW +G
Sbjct: 698 YKKKKKELQGDGPPSSPTNDPTVKYETQPRFITATGGT-LHMYQLEGLNWLRFSWAQGTD 756
Query: 502 CILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVY 561
ILADEMGLGKTIQTI FL L+ E GPFL+ PLST+ +W+RE Q WA + V Y
Sbjct: 757 TILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTY 816
Query: 562 LGDINSRNMIRTHEWTHHQTK--------------RLKFNILLTTYEILLKDKAFLGGLN 607
GD +SR +IR +E++ ++KF++LLT+YE++ D+A LG +
Sbjct: 817 TGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIR 876
Query: 608 WAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSS 667
WA + VDEAHRLKN+ S ++ L +K +H+LL+TGTPLQN+L+EL+ LL+F+ PE+F++
Sbjct: 877 WACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNN 936
Query: 668 WEDFEEEHGK-GREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYY 726
E F EE +E LH L P +LRR+K DV K++PAK E I+R+E+S +QK+YY
Sbjct: 937 LEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYY 996
Query: 727 KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYL--IKPPDNNEFYNKQEALQHLI 784
K+ILTRN++AL+ G+ LNIMM+LKKCCNH YL + ++ + + LI
Sbjct: 997 KYILTRNFEALNSRGGGNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALI 1056
Query: 785 RSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRK 844
+SSGKL+LL K+L +L+E+G+RVLIFSQM +MLD+L ++L Y + ++R+DG I G LR+
Sbjct: 1057 KSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQ 1116
Query: 845 QALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQK 904
+A+D FNA G++ FCFLLSTRAGGLGINLA+ADTV+IFDSDWNP ND+QA +RAHRIGQ
Sbjct: 1117 EAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQA 1176
Query: 905 KQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEE 964
+V IYR VT+ SVEE I + AK+KM+L HLV++ S + +K+E
Sbjct: 1177 NKVMIYRFVTRASVEERITQVAKRKMMLTHLVVR------------PGLGSKAGSMSKQE 1224
Query: 965 LSAILKFGAEELFK-EPEGEEQEPQ----EMDIDEILKRAETHEN--EPGPLTVGDELLS 1017
L ILKFG EELFK E EGE +E D + I + + +++ E + +E LS
Sbjct: 1225 LDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLS 1284
Query: 1018 QFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYM-LPRMRNC 1076
FKVA + +ED IE E ER EE + D +L +++ E++ L + +
Sbjct: 1285 SFKVAQYVVREEDKIE-EIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRV 1343
Query: 1077 AKQISFN--GSEGRRSRSRRYSGS-----DSDSISEGKRPKKR----GRPRTIP------ 1119
KQ+++N E + ++S GS D D EG+R KR + + +P
Sbjct: 1344 RKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPPLLARV 1403
Query: 1120 --RENIKGFSDAEIRRFIKSYKKFGGP 1144
+ GF+ + + F+ + ++G P
Sbjct: 1404 GGNIEVLGFNTRQRKAFLNAVMRWGMP 1430
>gi|52630322 chromodomain helicase DNA binding protein 3 isoform 2
[Homo sapiens]
Length = 1966
Score = 566 bits (1458), Expect = e-161
Identities = 358/927 (38%), Positives = 527/927 (56%), Gaps = 105/927 (11%)
Query: 298 EADGDPNAGFEKNKEP-GEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKD 356
+ADG+P+ + + E ++ +KW G S+ H +W E L+ + + NY++K+
Sbjct: 529 QADGNPDVPPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLE---IFHLVMYRNYQRKN 585
Query: 357 -----------------QETKRWLKNASPEDVE--YYNCQQELTDDLHKQYQIVERIIAH 397
+ KR +K+ ++E YY + ++ V RII H
Sbjct: 586 DMDEPPPLDYGSGEDDGKSDKRKVKDPHYAEMEEKYYRF------GIKPEWMTVHRIINH 639
Query: 398 SNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQ--SKTTPFKDCK 455
S K G Y KW+ LPY + +WE+ + +++ Y+ + P + K
Sbjct: 640 SVDKK--GNYHYLVKWRDLPYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRK 697
Query: 456 VLKQRPRF--------------VALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNS 501
K++ V + QP +I G L YQL GLNWL SW +G
Sbjct: 698 YKKKKKELQGDGPPSSPTNDPTVKYETQPRFITATGGT-LHMYQLEGLNWLRFSWAQGTD 756
Query: 502 CILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVY 561
ILADEMGLGKTIQTI FL L+ E GPFL+ PLST+ +W+RE Q WA + V Y
Sbjct: 757 TILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTY 816
Query: 562 LGDINSRNMIRTHEWTHHQTK--------------RLKFNILLTTYEILLKDKAFLGGLN 607
GD +SR +IR +E++ ++KF++LLT+YE++ D+A LG +
Sbjct: 817 TGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIR 876
Query: 608 WAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSS 667
WA + VDEAHRLKN+ S ++ L +K +H+LL+TGTPLQN+L+EL+ LL+F+ PE+F++
Sbjct: 877 WACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNN 936
Query: 668 WEDFEEEHGK-GREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYY 726
E F EE +E LH L P +LRR+K DV K++PAK E I+R+E+S +QK+YY
Sbjct: 937 LEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYY 996
Query: 727 KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYL--IKPPDNNEFYNKQEALQHLI 784
K+ILTRN++AL+ G+ LNIMM+LKKCCNH YL + ++ + + LI
Sbjct: 997 KYILTRNFEALNSRGGGNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALI 1056
Query: 785 RSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRK 844
+SSGKL+LL K+L +L+E+G+RVLIFSQM +MLD+L ++L Y + ++R+DG I G LR+
Sbjct: 1057 KSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQ 1116
Query: 845 QALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQK 904
+A+D FNA G++ FCFLLSTRAGGLGINLA+ADTV+IFDSDWNP ND+QA +RAHRIGQ
Sbjct: 1117 EAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQA 1176
Query: 905 KQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEE 964
+V IYR VT+ SVEE I + AK+KM+L HLV++ S + +K+E
Sbjct: 1177 NKVMIYRFVTRASVEERITQVAKRKMMLTHLVVR------------PGLGSKAGSMSKQE 1224
Query: 965 LSAILKFGAEELFK-EPEGEEQEPQ----EMDIDEILKRAETHEN--EPGPLTVGDELLS 1017
L ILKFG EELFK E EGE +E D + I + + +++ E + +E LS
Sbjct: 1225 LDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLS 1284
Query: 1018 QFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYM-LPRMRNC 1076
FKVA + +ED IE E ER EE + D +L +++ E++ L + +
Sbjct: 1285 SFKVAQYVVREEDKIE-EIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRV 1343
Query: 1077 AKQISFN--GSEGRRSRSRRYSGS-----DSDSISEGKRPKKR----GRPRTIP------ 1119
KQ+++N E + ++S GS D D EG+R KR + + +P
Sbjct: 1344 RKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPPLLARV 1403
Query: 1120 --RENIKGFSDAEIRRFIKSYKKFGGP 1144
+ GF+ + + F+ + ++G P
Sbjct: 1404 GGNIEVLGFNTRQRKAFLNAVMRWGMP 1430
>gi|158420731 chromodomain helicase DNA binding protein 3 isoform 3
[Homo sapiens]
Length = 2059
Score = 566 bits (1458), Expect = e-161
Identities = 358/927 (38%), Positives = 527/927 (56%), Gaps = 105/927 (11%)
Query: 298 EADGDPNAGFEKNKEP-GEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKD 356
+ADG+P+ + + E ++ +KW G S+ H +W E L+ + + NY++K+
Sbjct: 588 QADGNPDVPPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLE---IFHLVMYRNYQRKN 644
Query: 357 -----------------QETKRWLKNASPEDVE--YYNCQQELTDDLHKQYQIVERIIAH 397
+ KR +K+ ++E YY + ++ V RII H
Sbjct: 645 DMDEPPPLDYGSGEDDGKSDKRKVKDPHYAEMEEKYYRF------GIKPEWMTVHRIINH 698
Query: 398 SNQKSAAGYPDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQ--SKTTPFKDCK 455
S K G Y KW+ LPY + +WE+ + +++ Y+ + P + K
Sbjct: 699 SVDKK--GNYHYLVKWRDLPYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPAQPRK 756
Query: 456 VLKQRPRF--------------VALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNS 501
K++ V + QP +I G L YQL GLNWL SW +G
Sbjct: 757 YKKKKKELQGDGPPSSPTNDPTVKYETQPRFITATGGT-LHMYQLEGLNWLRFSWAQGTD 815
Query: 502 CILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVY 561
ILADEMGLGKTIQTI FL L+ E GPFL+ PLST+ +W+RE Q WA + V Y
Sbjct: 816 TILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTY 875
Query: 562 LGDINSRNMIRTHEWTHHQTK--------------RLKFNILLTTYEILLKDKAFLGGLN 607
GD +SR +IR +E++ ++KF++LLT+YE++ D+A LG +
Sbjct: 876 TGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIR 935
Query: 608 WAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSS 667
WA + VDEAHRLKN+ S ++ L +K +H+LL+TGTPLQN+L+EL+ LL+F+ PE+F++
Sbjct: 936 WACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNN 995
Query: 668 WEDFEEEHGK-GREYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYY 726
E F EE +E LH L P +LRR+K DV K++PAK E I+R+E+S +QK+YY
Sbjct: 996 LEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYY 1055
Query: 727 KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYL--IKPPDNNEFYNKQEALQHLI 784
K+ILTRN++AL+ G+ LNIMM+LKKCCNH YL + ++ + + LI
Sbjct: 1056 KYILTRNFEALNSRGGGNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALI 1115
Query: 785 RSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRK 844
+SSGKL+LL K+L +L+E+G+RVLIFSQM +MLD+L ++L Y + ++R+DG I G LR+
Sbjct: 1116 KSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQ 1175
Query: 845 QALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQK 904
+A+D FNA G++ FCFLLSTRAGGLGINLA+ADTV+IFDSDWNP ND+QA +RAHRIGQ
Sbjct: 1176 EAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQA 1235
Query: 905 KQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEE 964
+V IYR VT+ SVEE I + AK+KM+L HLV++ S + +K+E
Sbjct: 1236 NKVMIYRFVTRASVEERITQVAKRKMMLTHLVVR------------PGLGSKAGSMSKQE 1283
Query: 965 LSAILKFGAEELFK-EPEGEEQEPQ----EMDIDEILKRAETHEN--EPGPLTVGDELLS 1017
L ILKFG EELFK E EGE +E D + I + + +++ E + +E LS
Sbjct: 1284 LDDILKFGTEELFKDENEGENKEEDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLS 1343
Query: 1018 QFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYM-LPRMRNC 1076
FKVA + +ED IE E ER EE + D +L +++ E++ L + +
Sbjct: 1344 SFKVAQYVVREEDKIE-EIEREIIKQEENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRV 1402
Query: 1077 AKQISFN--GSEGRRSRSRRYSGS-----DSDSISEGKRPKKR----GRPRTIP------ 1119
KQ+++N E + ++S GS D D EG+R KR + + +P
Sbjct: 1403 RKQVNYNDAAQEDQDNQSEYSVGSEEEDEDFDERPEGRRQSKRQLRNEKDKPLPPLLARV 1462
Query: 1120 --RENIKGFSDAEIRRFIKSYKKFGGP 1144
+ GF+ + + F+ + ++G P
Sbjct: 1463 GGNIEVLGFNTRQRKAFLNAVMRWGMP 1489
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 543 bits (1398), Expect = e-154
Identities = 349/947 (36%), Positives = 510/947 (53%), Gaps = 135/947 (14%)
Query: 315 EIQYLIKWKGWSHIHNTWETE------ETLKQQNVRGMKKLD-----NYKKKDQETKRWL 363
E ++ +KW G S+ H +W E T+ +N + +D +Y D++ K
Sbjct: 508 EREFFVKWAGLSYWHCSWVKELQLELYHTVMYRNYQRKNDMDEPPPFDYGSGDEDGKS-- 565
Query: 364 KNASPEDVEYYNCQQELTD-DLHKQYQIVERIIAHSNQKSAAGYPDYYCKWQGLPYSECS 422
+ +D Y ++ + ++ ++ RI+ HS K G Y KW+ LPY +C+
Sbjct: 566 EKRKNKDPLYAKMEERFYRYGIKPEWMMIHRILNHSFDKK--GDVHYLIKWKDLPYDQCT 623
Query: 423 WEDGALISKKFQACIDEYFSRNQ--------------SKTTPFKDCKVLKQRPR-----F 463
WE + + Y+ + K +D K K
Sbjct: 624 WEIDDIDIPYYDNLKQAYWGHRELMLGEDTRLPKRLLKKGKKLRDDKQEKPPDTPIVDPT 683
Query: 464 VALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYL 523
V KQP YI G L YQL GLNWL SW +G ILADEMGLGKT+QTI FL L
Sbjct: 684 VKFDKQPWYIDSTGGT-LHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSL 742
Query: 524 FHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTK- 582
+ E GP+L+ PLST+ +W+RE + WA V Y GD SR++IR +E++
Sbjct: 743 YKEGHSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFEDNAI 802
Query: 583 -------------RLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKT 629
++KF++LLT+YE++ D+A LG + WA + VDEAHRLKN+ S ++
Sbjct: 803 RSGKKVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFRV 862
Query: 630 LIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGK-GREYGYASLHK 688
L +K +++LL+TGTPLQN+L+EL+ LL+F+ PE+F++ E F EE +E LH
Sbjct: 863 LNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHD 922
Query: 689 ELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGF 748
L P +LRR+K DV K++PAK E I+R+E+S +QK+YYK+ILTRN++AL+ G+
Sbjct: 923 LLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGGNQVSL 982
Query: 749 LNIMMELKKCCNHCYLIK------PPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRE 802
LNIMM+LKKCCNH YL P N Y+ L++SSGKL+LL K+L +LR+
Sbjct: 983 LNIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGSS----LVKSSGKLMLLQKMLKKLRD 1038
Query: 803 RGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLL 862
G+RVLIFSQM +MLD+L ++L+Y + ++R+DG I G LR++A+D FNA G++ FCFLL
Sbjct: 1039 EGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFLL 1098
Query: 863 STRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDI 922
STRAGGLGINLA+ADTV+I+DSDWNP ND+QA +RAHRIGQ K+V IYR VT+ SVEE I
Sbjct: 1099 STRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERI 1158
Query: 923 LERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKE--- 979
+ AK+KM+L HLV++ S S K+EL ILKFG EELFK+
Sbjct: 1159 TQVAKRKMMLTHLVVR------------PGLGSKSGSMTKQELDDILKFGTEELFKDDVE 1206
Query: 980 -----------------------------------PEGEEQEPQEMD--------IDEIL 996
P G+ ++ ++ I ++L
Sbjct: 1207 GMMSQGQRPVTPIPDVQSSKGGNLAASAKKKHGSTPPGDNKDVEDSSVIHYDDAAISKLL 1266
Query: 997 KRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLE 1056
R + ++ L +E LS FKVA + +ED +E E ER EE + D +L
Sbjct: 1267 DRNQDATDDT-ELQNMNEYLSSFKVAQYVVREEDGVE-EVEREIIKQEENVDPDYWEKLL 1324
Query: 1057 EEERQKELEEIYM-LPRMRNCAKQISFNGS---------EGRRSRSRRYSGSDSDSISEG 1106
+++ E++ L + + KQ+++N + E ++S GS+ +
Sbjct: 1325 RHHYEQQQEDLARNLGKGKRIRKQVNYNDASQEDQEWQDELSDNQSEYSIGSEDEDEDFE 1384
Query: 1107 KRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGPLERLDAIAR 1153
+RP+ + R R +K D + + + GG +E L AR
Sbjct: 1385 ERPEGQSGRRQ-SRRQLKSDRDKPLPPLL---ARVGGNIEVLGFNAR 1427
Score = 41.2 bits (95), Expect = 0.009
Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 15/122 (12%)
Query: 122 SEEDSSSSEDSDDS------SSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSC 175
SEE+ E DD S K+K K ++ + G + +D SE E +
Sbjct: 26 SEEEDGGLEAFDDFFPVEPVSLPKKKKPKKLKENKCKGKRKKKEGSNDELSENEEDLEEK 85
Query: 176 DETE-SDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRR 234
E+E SDY P NK K +K +++ + K K+++ D E+D+D+ K S +
Sbjct: 86 SESEGSDYSP-NKKKKKKLKDKKEKK-------AKRKKKDEDEDDNDDGCLKEPKSSGQL 137
Query: 235 QA 236
A
Sbjct: 138 MA 139
Score = 33.1 bits (74), Expect = 2.4
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 20/88 (22%)
Query: 103 KKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGS 162
K ++++++ + S N E+ S SE SD S ++ K+KK KD+
Sbjct: 62 KGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDK--------------- 106
Query: 163 DSESEEEREKSSCDETESD----YEPKN 186
E + +R+K DE ++D EPK+
Sbjct: 107 -KEKKAKRKKKDEDEDDNDDGCLKEPKS 133
Score = 31.6 bits (70), Expect = 6.9
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 1/78 (1%)
Query: 1249 FDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADY 1308
+DI W + D LL GI +GY W+ I+ DP + ++ + K +
Sbjct: 1733 YDI-WHRRHDYWLLAGIVTHGYARWQDIQNDPRYMILNEPFKSEVHKGNYLEMKNKFLAR 1791
Query: 1309 LIKLLSRDLAKKEALSGA 1326
KLL + L +E L A
Sbjct: 1792 RFKLLEQALVIEEQLRRA 1809
Score = 31.2 bits (69), Expect = 9.0
Identities = 28/109 (25%), Positives = 44/109 (40%), Gaps = 28/109 (25%)
Query: 177 ETESDYEPKNKVKSRKPQNRSKSKNGKKILGQK--------KRQIDSSEEDDDEEDYDND 228
+T+ P + K + ++ K GKK G K KR+ SS E+D+ E+ D D
Sbjct: 243 KTKEGKGPGVRKKIKGSKDGKKKGKGKKTAGLKFRFGGISNKRKKGSSSEEDEREESDFD 302
Query: 229 ------------------KRSSRRQATVNVSYKEDEEMKTDSDDLLEVC 259
K+S RR+ + + + +TD D EVC
Sbjct: 303 SASIHSASVRSECSAALGKKSKRRRKKKRID--DGDGYETDHQDYCEVC 349
Score = 31.2 bits (69), Expect = 9.0
Identities = 24/101 (23%), Positives = 45/101 (44%), Gaps = 18/101 (17%)
Query: 103 KKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGS 162
K + +QQQ + N G + + +D+S E D++WQ S + S+
Sbjct: 1322 KLLRHHYEQQQEDLARNLGKGKRIRKQVNYNDASQE-------DQEWQDELSDNQSEYSI 1374
Query: 163 DSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGK 203
SE E+E D+E + + +S + Q+R + K+ +
Sbjct: 1375 GSEDEDE-----------DFEERPEGQSGRRQSRRQLKSDR 1404
>gi|54112403 chromodomain helicase DNA binding protein 7 [Homo
sapiens]
Length = 2997
Score = 518 bits (1333), Expect = e-146
Identities = 383/1129 (33%), Positives = 572/1129 (50%), Gaps = 160/1129 (14%)
Query: 89 SSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDD-------------- 134
S P+ V+ L +QQ QQ++ + +N ED S DD
Sbjct: 574 SGPNAQLVKSDDYLPSIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNRNS 633
Query: 135 --SSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNK---VK 189
S E K+KK + + P + E +E +E + + EPK K
Sbjct: 634 LDGSQEEKKKKKRSK-----AKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTA 688
Query: 190 SRKPQNRSKSKNGK---------------KILGQKKRQIDS----SEEDDDEEDYDNDKR 230
+ KP++ KS N K K G + +D S +++ED KR
Sbjct: 689 TPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGVQKR 748
Query: 231 SSRRQATVNVSYKEDEEMKTDSD--DLLEVCGEDVP----QPEEEEF-----ETIERFMD 279
S RQ Y ED E K + D + G D P Q E++E +E+ M
Sbjct: 749 RSSRQVK-RKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVDAEGPVVEKIMS 807
Query: 280 CRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEI----QYLIKWKGWSHIHNTWETE 335
R +K KE GE ++ +K+K +S++H W +
Sbjct: 808 SR------------------------SVKKQKESGEEVEIEEFYVKYKNFSYLHCQWASI 843
Query: 336 ETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQELTDDL-HKQYQIVERI 394
E L++ R +K+ +K K + K E+ D+L + Y V+RI
Sbjct: 844 EDLEKDK-RIQQKIKRFKAKQGQNK---------------FLSEIEDELFNPDYVEVDRI 887
Query: 395 IAHSNQKSAAGYP--DYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFK 452
+ + G P Y KW LPY + +WE I QA I+E F + S+ +
Sbjct: 888 MDFARSTDDRGEPVTHYLVKWCSLPYEDSTWERRQDID---QAKIEE-FEKLMSREPETE 943
Query: 453 DCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGK 512
+RP KK S +LR+YQL G+NWL +W +CILADEMGLGK
Sbjct: 944 RV----ERPPADDWKKSESSREYKNNNKLREYQLEGVNWLLFNWYNMRNCILADEMGLGK 999
Query: 513 TIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIR 572
TIQ+I+FL Y + ++GPFL++ PLST+ +W+RE +TW +++N VVY G SR I+
Sbjct: 1000 TIQSITFL-YEIYLKGIHGPFLVIAPLSTIPNWEREFRTW-TELNVVVYHGSQASRRTIQ 1057
Query: 573 THEWTHHQTK------RLKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLL 626
+E + KF+ ++TT+E++L D L + W + +DEAHRLKN + L
Sbjct: 1058 LYEMYFKDPQGRVIKGSYKFHAIITTFEMILTDCPELRNIPWRCVVIDEAHRLKNRNCKL 1117
Query: 627 YKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGR-EYGYAS 685
+ L H++L+TGTPLQN+++EL+SLLHF+ P +F S F +E G + E
Sbjct: 1118 LEGLKMMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSRFPSETTFMQEFGDLKTEEQVQK 1177
Query: 686 LHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGS-KGS 744
L L+P +LRR+K+DVEK+L K E I+ +E++ +QK+YY+ IL +N+ LSKG + +
Sbjct: 1178 LQAILKPMMLRRLKEDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFTFLSKGGGQAN 1237
Query: 745 TSGFLNIMMELKKCCNHCYLIKPPDNN---EFYNKQEA------LQHLIRSSGKLILLDK 795
LN MMEL+KCCNH YLI + EF A LQ +I+++GKL+L+DK
Sbjct: 1238 VPNLLNTMMELRKCCNHPYLINGAEEKILEEFKETHNAESPDFQLQAMIQAAGKLVLIDK 1297
Query: 796 LLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGS 855
LL +L+ G+RVLIFSQMVR LDIL +YL R++P++R+DG ++G LR+ A+D F+ S
Sbjct: 1298 LLPKLKAGGHRVLIFSQMVRCLDILEDYLIQRRYPYERIDGRVRGNLRQAAIDRFSKPDS 1357
Query: 856 EDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTK 915
+ F FLL TRAGGLGINL +ADT +IFDSDWNPQNDLQAQAR HRIGQ K V IYRL+T+
Sbjct: 1358 DRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKSVKIYRLITR 1417
Query: 916 GSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEE 975
S E ++ ++A K+ LD V+Q M +G+ +A + +K+E+ +L+ GA
Sbjct: 1418 NSYEREMFDKASLKLGLDKAVLQSM--SGRE-----NATNGVQQLSKKEIEDLLRKGAYG 1470
Query: 976 LFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDE-LLSQFKVANF-SNMDEDDIE 1033
+ E E + E DID+IL R TH +T+ E S F A+F ++ + DI
Sbjct: 1471 ALMDEEDEGSKFCEEDIDQILLR-RTH-----TITIESEGKGSTFAKASFVASGNRTDIS 1524
Query: 1034 LEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSR 1093
L+ + W ++ L+ + + PR+R + S +
Sbjct: 1525 LDDPNFWQKWA------KKAELDIDALNGRNNLVIDTPRVRKQTRLY----SAVKEDELM 1574
Query: 1094 RYSGSDSDSISEGKRPKKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFG 1142
+S +SDS K +PR P++ +G++ +E R K+ +G
Sbjct: 1575 EFSDLESDS-----EEKPCAKPRR-PQDKSQGYARSECFRVEKNLLVYG 1617
Score = 38.1 bits (87), Expect = 0.074
Identities = 15/40 (37%), Positives = 26/40 (65%), Gaps = 1/40 (2%)
Query: 1253 WGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKI-LPD 1291
W KE D +LLIG++++GY + ++ DP L ++ +PD
Sbjct: 1786 WDKEADKSLLIGVFKHGYEKYNSMRADPALCFLERVGMPD 1825
Score = 33.5 bits (75), Expect = 1.8
Identities = 56/231 (24%), Positives = 89/231 (38%), Gaps = 41/231 (17%)
Query: 1210 NAKLVISHEEELIPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKED----------DS 1259
NA+LV S ++ +P SI P+++K+ H A +GK+D +
Sbjct: 577 NAQLVKS--DDYLP---SIEQQPQQKKKKKKNNHIVAEDPSKGFGKDDFPGGVDNQELNR 631
Query: 1260 NLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAK 1319
N L G E E K + P +P +K + K+ +T I ++
Sbjct: 632 NSLDGSQE------EKKKKKRSKAKKDPKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKA 685
Query: 1320 KEALSGAGSSKRR-------KARAKKNKAMKS-IKVKEEIKSDSSPLPSEKSDEDDDKLS 1371
K A SSK+ +A A K K K + E D +P PS +ED+D
Sbjct: 686 KTATPKPKSSKKSSNKKPDSEASALKKKVNKGKTEGSENSDLDKTPPPSPPPEEDEDPGV 745
Query: 1372 ESKSDGRERSKKSSVSDAPVHIT--------ASGEPVPI----SEESEELD 1410
+ + R+ +K D I+ A+G P SE+ E +D
Sbjct: 746 QKRRSSRQVKRKRYTEDLEFKISDEEADDADAAGRDSPSNTSQSEQQESVD 796
Score = 33.1 bits (74), Expect = 2.4
Identities = 32/141 (22%), Positives = 60/141 (42%), Gaps = 17/141 (12%)
Query: 7 EESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESE- 65
EE ++ E + ++ GSG S ++ SS ++ + G+++GS+S SE
Sbjct: 2176 EEPENPAAKEKCEGKEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSISEK 2235
Query: 66 -SDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEE 124
S+ E K++ D S P AV R + ++ AS ++ +E
Sbjct: 2236 GSEEDEEEKLED-----DDKSEESSQPEAGAVSRG--------KNFDEESNASMSTARDE 2282
Query: 125 --DSSSSEDSDDSSSEVKRKK 143
D ED D S +++ ++
Sbjct: 2283 TRDGFYMEDGDPSVAQLLHER 2303
Score = 32.7 bits (73), Expect = 3.1
Identities = 25/105 (23%), Positives = 51/105 (48%), Gaps = 11/105 (10%)
Query: 96 VQRSAILKKQQQQQQQQQHQASSNS--GSEEDSS-------SSEDSDDSSSEVKRKKHKD 146
+Q +L++ + + ++ ++ A+ G EE+ S ++ + +S VK +
Sbjct: 2162 IQDERVLEQAEGKVEEPENPAAKEKCEGKEEEEETDGSGKESKQECEAEASSVKNELKGV 2221
Query: 147 EDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSR 191
E +GS S S+ GS+ + EE+ E D++E +P+ SR
Sbjct: 2222 EVGADTGSKSISEKGSEEDEEEKLEDD--DKSEESSQPEAGAVSR 2264
Score = 31.6 bits (70), Expect = 6.9
Identities = 38/167 (22%), Positives = 69/167 (41%), Gaps = 21/167 (12%)
Query: 1222 IPLHKSIPSDPEERKQYTIPCHTKAAHFDIDWGKEDDSNLLIGIYEYGYGSWEMIKMDPD 1281
+P+H+ PS+P K +P T+ + + K DD Y + +
Sbjct: 551 VPVHQHSPSEPFLEKP--VPDMTQVSGPNAQLVKSDD---------YLPSIEQQPQQKKK 599
Query: 1282 LSLTHKILPDDPDKKPQAKQLQTRADYLIKLLSRDLAKKEALSGAGSSKRRKARAKKNK- 1340
+ I+ +DP K D +++L + +L G+ K++K R+K K
Sbjct: 600 KKKNNHIVAEDPSKGFGKDDFPGGVD------NQEL-NRNSLDGSQEEKKKKKRSKAKKD 652
Query: 1341 --AMKSIKVKEEIKSDSSPLPSEKSDEDDDKLSESKSDGRERSKKSS 1385
K K K+E K +P + E +K +++ + + SKKSS
Sbjct: 653 PKEPKEPKEKKEPKEPKTPKAPKIPKEPKEKKAKTATPKPKSSKKSS 699
Score = 31.6 bits (70), Expect = 6.9
Identities = 28/99 (28%), Positives = 41/99 (41%), Gaps = 12/99 (12%)
Query: 161 GSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKIL---------GQKKR 211
G E E K C+ E + E K K + +++ + K L G K
Sbjct: 2173 GKVEEPENPAAKEKCEGKEEEEETDGSGKESKQECEAEASSVKNELKGVEVGADTGSKSI 2232
Query: 212 QIDSSEEDDDE--EDYDNDKRSSRRQA-TVNVSYKEDEE 247
SEED++E ED D + SS+ +A V+ DEE
Sbjct: 2233 SEKGSEEDEEEKLEDDDKSEESSQPEAGAVSRGKNFDEE 2271
>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
sapiens]
Length = 2302
Score = 516 bits (1328), Expect = e-146
Identities = 342/932 (36%), Positives = 515/932 (55%), Gaps = 100/932 (10%)
Query: 163 DSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGK--KILGQKKRQIDSSEEDD 220
+ E E++R K S E + +PK S + + KSK ++G+K+++ SS+ D
Sbjct: 216 EEEGEKKRRKKSAGERLKEEKPKKSKTSGASKTKGKSKLNTITPVVGKKRKRNTSSDNSD 275
Query: 221 ----------DEEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLE------------V 258
++E+ KR S RQ Y ED ++K D+ E +
Sbjct: 276 VEVMPAQSPREDEESSIQKRRSNRQVK-RKKYTEDLDIKITDDEEEEEVDVTGPIKPEPI 334
Query: 259 CGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNAGFEKNKEPGEIQY 318
E V +P+ E +++ F++ A + P+ + + +E +
Sbjct: 335 LPEPVQEPDGETLPSMQFFVENPSEEDAAIVDKVLSMRIVKKELPSGQYTEAEE-----F 389
Query: 319 LIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKNASPEDVEYYNCQQ 378
+K+K +S++H W T L++ R +KL +K K + + + ED E +N
Sbjct: 390 FVKYKNYSYLHCEWATISQLEKDK-RIHQKLKRFKTKMAQMRHFFH----EDEEPFN--- 441
Query: 379 ELTDDLHKQYQIVERII--AHSNQKSAAGYPDYYC-KWQGLPYSECSWEDGALISKKFQA 435
Y V+RI+ +HS K YY KW LPY + +WE +
Sbjct: 442 -------PDYVEVDRILDESHSIDKDNGEPVIYYLVKWCSLPYEDSTWE--------LKE 486
Query: 436 CIDE----YFSRNQSKTTPFKDCKVLKQRPRFVALKKQPSYIGGHEGLELRDYQLNGLNW 491
+DE F R QS+ K RP+ A KK +LR+YQL G+NW
Sbjct: 487 DVDEGKIREFKRIQSRHPELKRVN----RPQASAWKKLELSHEYKNRNQLREYQLEGVNW 542
Query: 492 LAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLSTLTSWQREIQT 551
L +W +CILADEMGLGKTIQ+I+FL +++ ++GPFL++ PLST+T+W+RE T
Sbjct: 543 LLFNWYNRQNCILADEMGLGKTIQSIAFLQEVYNVG-IHGPFLVIAPLSTITNWEREFNT 601
Query: 552 WASQMNAVVYLGDINSRNMIRTHEWTHHQTK------RLKFNILLTTYEILLKDKAFLGG 605
W ++MN +VY G + SR MI+ +E ++ KF+ L+TT+E++L D L
Sbjct: 602 W-TEMNTIVYHGSLASRQMIQQYEMYCKDSRGRLIPGAYKFDALITTFEMILSDCPELRE 660
Query: 606 LNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKF 665
+ W + +DEAHRLKN + L +L H++L+TGTPLQN+++EL+SLLHF+ P +F
Sbjct: 661 IEWRCVIIDEAHRLKNRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSQF 720
Query: 666 SSWEDFEEEHGKGR-EYGYASLHKELEPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQ 724
S +F ++ G + E L L+P +LRR+K+DVEK+L K E I+ +E++ +QK+
Sbjct: 721 PSESEFLKDFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAPKQETIIEVELTNIQKK 780
Query: 725 YYKWILTRNYKALSKGSKGSTS--GFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEA--- 779
YY+ IL +N+ LSKG+ G T+ LN MMEL+KCCNH YLI + +EA
Sbjct: 781 YYRAILEKNFSFLSKGA-GHTNMPNLLNTMMELRKCCNHPYLINGAEEKILTEFREACHI 839
Query: 780 ------LQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQR 833
LQ ++RS+GKL+L+DKLL +L+ G++VLIFSQMVR LDIL +YL R++ ++R
Sbjct: 840 IPHDFHLQAMVRSAGKLVLIDKLLPKLKAGGHKVLIFSQMVRCLDILEDYLIQRRYLYER 899
Query: 834 LDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQ 893
+DG ++G LR+ A+D F+ S+ F FLL TRAGGLGINL +ADT +IFDSDWNPQNDLQ
Sbjct: 900 IDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQ 959
Query: 894 AQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGKTVLHTGSA 953
AQAR HRIGQ K V +YRL+T+ S E ++ ++A K+ LD V+Q M +G+ TG
Sbjct: 960 AQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSM--SGRDGNITG-- 1015
Query: 954 PSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGD 1013
F+K+E+ +L+ GA E + E + E DID+IL R T +T+
Sbjct: 1016 ---IQQFSKKEIEDLLRKGAYAAIMEEDDEGSKFCEEDIDQILLRRTT------TITIES 1066
Query: 1014 E-LLSQFKVANF-SNMDEDDIELEPERNSKNW 1043
E S F A+F ++ + DI L+ + W
Sbjct: 1067 EGKGSTFAKASFVASENRTDISLDDPNFWQKW 1098
Score = 37.7 bits (86), Expect = 0.097
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 3/77 (3%)
Query: 130 EDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESD-YEPKNKV 188
ED DDS SE+ K S S S S S S ESE+E+E+ D++ S Y+ ++ +
Sbjct: 1785 EDEDDSDSELDLSKLSPS--SSSSSSSSSSSSSTDESEDEKEEKLTDQSRSKLYDEESLL 1842
Query: 189 KSRKPQNRSKSKNGKKI 205
Q+ +++G+++
Sbjct: 1843 SLTMSQDGFPNEDGEQM 1859
Score = 36.6 bits (83), Expect = 0.22
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%)
Query: 1253 WGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKI-LPDD 1292
W E D +LLIG++++GY + ++ DP L K PDD
Sbjct: 1346 WDSEADKSLLIGVFKHGYEKYNTMRADPALCFLEKAGRPDD 1386
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 12/71 (16%)
Query: 116 ASSNSGSEEDSSSSEDSDDSSSE----VKRKKHKDED----WQMSGSGSPSQSGSDSESE 167
+SS+S S SSS+++S+D E R K DE+ MS G P++ G E
Sbjct: 1803 SSSSSSSSSSSSSTDESEDEKEEKLTDQSRSKLYDEESLLSLTMSQDGFPNEDGEQMTPE 1862
Query: 168 ----EEREKSS 174
+ER+++S
Sbjct: 1863 LLLLQERQRAS 1873
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 515 bits (1326), Expect = e-145
Identities = 370/1104 (33%), Positives = 574/1104 (51%), Gaps = 145/1104 (13%)
Query: 99 SAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDS------SSEVKRKKHKDEDWQMS 152
+ + KK+++++ Q A+ S E + + E K+ K E Q
Sbjct: 90 TGVKKKRKKKEPGDQEGAAKGSKDREPKPKRKREPKEPKEPRKAKEPKKAKEHKEPKQKD 149
Query: 153 GSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQ 212
G+ + S ++E +EK SC ++ + + + K + P K K GK+ + +
Sbjct: 150 GAKKARKPREASGTKEAKEKRSCTDSAARTKSRKASKEQGPTPVEKKKKGKR---KSETT 206
Query: 213 IDSSEED------------DDEEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDD--LLEV 258
++S E D + E D+ KR S RQ Y ED + K DD + V
Sbjct: 207 VESLELDQGLTNPSLRSPEESTESTDSQKRRSGRQVKRR-KYNEDLDFKVVDDDGETIAV 265
Query: 259 CGE-------------DVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADGDPNA 305
G +P E++ IE+ + A+ T+ V G+P
Sbjct: 266 LGAGRTSALSASTLAWQAEEPPEDDANIIEKIL-----------ASKTVQEVHP-GEPPF 313
Query: 306 GFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKRWLKN 365
E + +K++ +S++H W T E L +++ R +K+ ++ K + K
Sbjct: 314 DLEL--------FYVKYRNFSYLHCKWATMEEL-EKDPRIAQKIKRFRNKQAQMKHIF-- 362
Query: 366 ASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSNQKSAAGYPD---YYCKWQGLPYSECS 422
P++ D + Y V+RI+ ++ K A + Y KW LPY E +
Sbjct: 363 TEPDE-----------DLFNPDYVEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEEST 411
Query: 423 WEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQ-----RPRFVALKKQPSYIGGHE 477
WE ++E + +K F+ +VL + RP + +K
Sbjct: 412 WE------------LEE--DVDPAKVKEFESLQVLPEIKHVERPASDSWQKLEKSREYKN 457
Query: 478 GLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVV 537
+LR+YQL G+NWL +W +CILADEMGLGKTIQ+I+FL+ +F ++GPFL++
Sbjct: 458 SNQLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLSEIFLRG-IHGPFLIIA 516
Query: 538 PLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKR------LKFNILLT 591
PLST+T+W+RE +TW ++MNA+VY G SR MI+ +E + + KF++++T
Sbjct: 517 PLSTITNWEREFRTW-TEMNAIVYHGSQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVIT 575
Query: 592 TYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLK 651
T+E++L D L ++W+ + +DEAHRLKN + L + L H++L+TGTPLQNS++
Sbjct: 576 TFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVE 635
Query: 652 ELWSLLHFIMPEKFSSWEDFEEEHGKGR-EYGYASLHKELEPFLLRRVKKDVEKSLPAKV 710
EL+SLL+F+ P +F S F EE G + E L L+P +LRR+K DVEK+L K
Sbjct: 636 ELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPMMLRRLKDDVEKNLAPKQ 695
Query: 711 EQILRMEMSALQKQYYKWILTRNYKALSKGS-KGSTSGFLNIMMELKKCCNHCYLIKPPD 769
E I+ +E++ +QK+YY+ IL +N+ L+KG+ + + +N MMEL+KCCNH YLI +
Sbjct: 696 ETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTMMELRKCCNHPYLINGAE 755
Query: 770 NN--EFYNKQEA-------LQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDIL 820
E + K + LQ +I+++GKL+L+DKLL +L G++VLIFSQMVR LDIL
Sbjct: 756 EKILEDFRKTHSPDAPDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDIL 815
Query: 821 AEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVV 880
+YL R++ ++R+DG ++G LR+ A+D F S+ F FLL TRAGGLGINL +ADT +
Sbjct: 816 EDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCI 875
Query: 881 IFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRM 940
IFDSDWNPQNDLQAQAR HRIGQ K V +YRL+T+ S E ++ ++A K+ LD V+Q +
Sbjct: 876 IFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDI 935
Query: 941 DTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAE 1000
+ G T + +K E+ +L+ GA + E E + E DID+IL+R
Sbjct: 936 NRKGGT--------NGVQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQR-R 986
Query: 1001 THENEPGPLTVGDE-LLSQFKVANF-SNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEE 1058
TH +T+ E S F A+F ++ + DI L+ + W +I D + E+E
Sbjct: 987 TH-----TITIQSEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKIAELDTEAKNEKE 1041
Query: 1059 ERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTI 1118
+ PR+R K +N E +S DSDS +RP + R
Sbjct: 1042 SL------VIDRPRVRKQTKH--YNSFE--EDELMEFSELDSDS---DERPTRSRRLNDK 1088
Query: 1119 PRENIKGFSDAEIRRFIKSYKKFG 1142
R ++ AE R K+ FG
Sbjct: 1089 ARRYLR----AECFRVEKNLLIFG 1108
Score = 38.5 bits (88), Expect = 0.057
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 31/146 (21%)
Query: 1253 WGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKI-LPDDPDKKPQAKQLQTRADYLIK 1311
W E D +LLIG++++GY + ++ DP L K+ +PD+ K
Sbjct: 1277 WDAEADKSLLIGVFKHGYERYNAMRADPALCFLEKVGMPDE------------------K 1318
Query: 1312 LLSRDLAKKEALSGAGSSKRRKARAKKNKAMKSIKVKEEIKSDSSPLPSE-KSDEDDDKL 1370
LS A++ G R K++ A E K D +E SD D
Sbjct: 1319 SLS---AEQGVTDGTSDIPERGNTDKEDNA--------EDKVDGLQKQTESSSDGGDGVF 1367
Query: 1371 SESKSDGRERSKKSSVSDAPVHITAS 1396
SE K D R S +P ++++
Sbjct: 1368 SEKKDDSRAAQDGSDPDKSPWPVSSA 1393
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 496 bits (1278), Expect = e-140
Identities = 376/1112 (33%), Positives = 562/1112 (50%), Gaps = 145/1112 (13%)
Query: 88 KSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDE 147
+ PS S K Q Q + + E +S + + S + + K + E
Sbjct: 483 RQPPSSKKSDGSGTYTKLQNTQVRVMSEKKQRKKVESESKQEKANRIISEAIAKAKERGE 542
Query: 148 ---DWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKK 204
MS P+ S E ++ R S +PK+K S+K + SK K K
Sbjct: 543 RNIPRVMSPENFPTASVEGKEEKKGRRMKS--------KPKDK-DSKKTKTCSKLKEKTK 593
Query: 205 I------LGQK-KRQIDSSEEDDDEE--------DYDNDKRSSRRQATVNVSYKEDEEMK 249
I LG+K KR+ +SS+E D E D D+ KR S RQ Y ED E K
Sbjct: 594 IGKLIITLGKKQKRKNESSDEISDAEQMPQHTLKDQDSQKRRSNRQIK-RKKYAEDIEGK 652
Query: 250 TDSDDL----------LEVCGED-----VPQPEEEEFETIERFMDCRIGRKGATGATTTI 294
+++ + GE V P EE+ +++ + R +K
Sbjct: 653 QSEEEVKGSMKIKKNSAPLPGEQPLQLFVENPSEEDAAIVDKILSSRTVKK--------- 703
Query: 295 YAVEADGDPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKK 354
+ + G + E ++ +K+K +S++H W TEE L + R +K+ +K
Sbjct: 704 -------EISPGVMIDTE----EFFVKYKNYSYLHCEWATEEQLLKDK-RIQQKIKRFKL 751
Query: 355 KDQETKRWLKNASPEDVEYYNCQQELTDDLHKQYQIVERIIAHSN-QKSAAGYPDYY--C 411
+ + + + E + Y V+R++ S + G P Y
Sbjct: 752 RQAQRAHFFADMEEEP-------------FNPDYVEVDRVLEVSFCEDKDTGEPVIYYLV 798
Query: 412 KWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVALKKQPS 471
KW LPY + +WE L A I+E+ S+ D + L + P + KK
Sbjct: 799 KWCSLPYEDSTWE---LKEDVDLAKIEEFEQLQASRP----DTRRLDRPPSNI-WKKIDQ 850
Query: 472 YIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYG 531
G +LR+YQL GLNWL +W +CILADEMGLGKTIQ+I+FL Y + G
Sbjct: 851 SRDYKNGNQLREYQLEGLNWLLFNWYNRRNCILADEMGLGKTIQSITFL-YEILLTGIRG 909
Query: 532 PFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTK------RLK 585
PFL++ PLST+ +W+RE +TW + +N VVY G + SR MI+ +E ++ +
Sbjct: 910 PFLIIAPLSTIANWEREFRTW-TDINVVVYHGSLISRQMIQQYEMYFRDSQGRIIRGAYR 968
Query: 586 FNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTP 645
F ++TT+E++L L + W + +DEAHRLKN + L + L H++L+TGTP
Sbjct: 969 FQAIITTFEMILGGCGELNAIEWRCVIIDEAHRLKNKNCKLLEGLKLMNLEHKVLLTGTP 1028
Query: 646 LQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGR-EYGYASLHKELEPFLLRRVKKDVEK 704
LQN+++EL+SLLHF+ P +F S F +E G + E L L+P +LRR+K+DVEK
Sbjct: 1029 LQNTVEELFSLLHFLEPLRFPSESTFMQEFGDLKTEEQVQKLQAILKPMMLRRLKEDVEK 1088
Query: 705 SLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTS--GFLNIMMELKKCCNHC 762
L K E I+ +E++ +QK+YY+ IL +N+ LSKG+ G T+ +N MMEL+KCCNH
Sbjct: 1089 KLAPKEETIIEVELTNIQKKYYRAILEKNFSFLSKGA-GQTNVPNLVNTMMELRKCCNHP 1147
Query: 763 YLIKPPDNN------EFYNKQEA---LQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQM 813
YLIK + + YN + LQ +I+S+GKL+L+DKLL +++ G++VLIFSQM
Sbjct: 1148 YLIKGAEEKILGEFRDTYNPAASDFHLQAMIQSAGKLVLIDKLLPKMKAGGHKVLIFSQM 1207
Query: 814 VRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINL 873
VR LDIL +YL ++++ ++R+DG ++G LR+ A+D F+ S+ F FLL TRAGGLGINL
Sbjct: 1208 VRCLDILEDYLIHKRYLYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINL 1267
Query: 874 ASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLD 933
+ADT +IFDSDWNPQNDLQAQAR HRIGQ K V +YRLVT+ S E ++ +RA K+ LD
Sbjct: 1268 TAADTCIIFDSDWNPQNDLQAQARCHRIGQNKAVKVYRLVTRNSYEREMFDRASLKLGLD 1327
Query: 934 HLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDID 993
V+Q M V +K+E+ +L+ GA E E E + E DID
Sbjct: 1328 KAVLQSMSGRESNV-------GGIQQLSKKEIEDLLRRGAYGAIMEEEDEGSKFCEEDID 1380
Query: 994 EI-LKRAETHENEPGPLTVGDE-LLSQFKVANF-SNMDEDDIELEPERNSKNWEEIIPED 1050
+I L+R +T +T+ E S F A+F ++ + DI L+ + W
Sbjct: 1381 QILLRRTKT-------ITIESEGRGSTFAKASFVASGNRTDISLDDPNFWQKWA------ 1427
Query: 1051 QRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPK 1110
++ ++ E + PR+R + S E S++ SEG
Sbjct: 1428 KKAEIDIEAISGRNSLVIDTPRIRKQTRPFSATKDE---------LAELSEAESEGDEKP 1478
Query: 1111 KRGRPRTIPRENIKGFSDAEIRRFIKSYKKFG 1142
K RP R N G+ E R K+ +G
Sbjct: 1479 KLRRP--CDRSN--GYGRTECFRVEKNLLVYG 1506
Score = 58.2 bits (139), Expect = 7e-08
Identities = 35/73 (47%), Positives = 40/73 (54%)
Query: 5 SDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSES 64
SD +S R+S S S S S S S SGSSS SSS SS+ S SS S S S S S S S
Sbjct: 2134 SDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSSSSSS 2193
Query: 65 ESDTSRENKVQAK 77
E S E + Q +
Sbjct: 2194 EESDSDEEEAQKR 2206
Score = 51.6 bits (122), Expect = 6e-06
Identities = 40/129 (31%), Positives = 59/129 (45%), Gaps = 17/129 (13%)
Query: 11 RNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDTSR 70
+ S SS SD DS +S S SSS SSS S S+SGSS S S S S + S S S TS
Sbjct: 2125 KRGSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSS 2184
Query: 71 ENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSE 130
SS S + + S +++ Q+++ H + + S S+++
Sbjct: 2185 -----------------SSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEESVASLSTTQ 2227
Query: 131 DSDDSSSEV 139
D S ++
Sbjct: 2228 DETQDSFQM 2236
Score = 47.4 bits (111), Expect = 1e-04
Identities = 37/122 (30%), Positives = 51/122 (41%), Gaps = 7/122 (5%)
Query: 5 SDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSES 64
S +S +S S S S S+S S S S SGSSS SSS S +S S S S S S S S
Sbjct: 2130 SSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSSSSS 2189
Query: 65 ESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEE 124
S + + + + K + K+ S Q + Q N+G+ E
Sbjct: 2190 SSSSEESDSDEEEAQKRESTTHMKAYDEESVASLST-------TQDETQDSFQMNNGTPE 2242
Query: 125 DS 126
+
Sbjct: 2243 SA 2244
Score = 37.7 bits (86), Expect = 0.097
Identities = 19/57 (33%), Positives = 32/57 (56%), Gaps = 3/57 (5%)
Query: 1253 WGKEDDSNLLIGIYEYGYGSWEMIKMDPDLSLTHKILPDDPDKKPQAKQLQTRADYL 1309
W + D +LLIG++++GY + I+ DP L ++ PD+K A + Q DY+
Sbjct: 1675 WDFDADKSLLIGVFKHGYEKYNTIRADPALCFLERV--GKPDEKAVAAE-QRANDYM 1728
Score = 35.8 bits (81), Expect = 0.37
Identities = 42/178 (23%), Positives = 66/178 (37%), Gaps = 17/178 (9%)
Query: 46 QSGSSDSDSGSESGSQSESESDTSRENKV-QAKPPKVDGAEFWKSSPSILAVQRSAILKK 104
QS +S S E+ + +SE + + + QA + G + + A R+ L
Sbjct: 2057 QSSEEESMSSVETRTLIKSEPVSPKNGVLPQATGDQKSGGKCETDRRMVAA--RTEPLTP 2114
Query: 105 QQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDS 164
++ + H+ S S S+ DS S S S S S S S S+SGS S
Sbjct: 2115 NPASKKPRVHKRGSESSSDSDSDSERSSCSSRSSSSSS---------SSSCSHSRSGSSS 2165
Query: 165 ESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDE 222
S SSC S S + S+ + + QK+ + D+E
Sbjct: 2166 SSS-----SSCSSASSSSSSSTSSSSSSSSSSSEESDSDEEEAQKRESTTHMKAYDEE 2218
Score = 35.0 bits (79), Expect = 0.63
Identities = 46/168 (27%), Positives = 69/168 (41%), Gaps = 21/168 (12%)
Query: 23 DSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSE-SGSQSESESDTSRENKVQAKPPKV 81
+SG+ GS S S+G + ++ S S++G E S S S S S T+ N A P
Sbjct: 2720 ESGTEDKKGSDSKE---SEGKTERTESQSSENGGENSVSSSPSTSSTAALNTAAAANPLA 2776
Query: 82 DGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSS---E 138
+P +L S IL + S S +++SD SS E
Sbjct: 2777 -------LNPLLL----SNILYPGMLLTPGLNLHIPTLSQSNTFDVQNKNSDLGSSKSVE 2825
Query: 139 VKRKKHKDEDWQMSGSGSPS---QSGSDSESEEEREKSSCDETESDYE 183
VK + + +D + G PS ++ +D SE+ S D T S E
Sbjct: 2826 VKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSE 2873
Score = 33.5 bits (75), Expect = 1.8
Identities = 23/68 (33%), Positives = 37/68 (54%), Gaps = 6/68 (8%)
Query: 11 RNSSGESSQS----DDDSGSASGSGSGSSSGSSSDGSSSQSGS--SDSDSGSESGSQSES 64
+NS SS+S ++DS G + S + +S+ GS +D+ SGS+S S S
Sbjct: 2814 KNSDLGSSKSVEVKEEDSRIKDQEDKGGTEPSPLNENSTDEGSEKADASSGSDSTSSSSE 2873
Query: 65 ESDTSREN 72
+SD+S E+
Sbjct: 2874 DSDSSNED 2881
Score = 32.7 bits (73), Expect = 3.1
Identities = 22/82 (26%), Positives = 30/82 (36%), Gaps = 4/82 (4%)
Query: 155 GSPSQSGSDSESE----EEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKK 210
GS S S SDS+SE R SS + + S S S +
Sbjct: 2127 GSESSSDSDSDSERSSCSSRSSSSSSSSSCSHSRSGSSSSSSSSCSSASSSSSSSTSSSS 2186
Query: 211 RQIDSSEEDDDEEDYDNDKRSS 232
SS E+ D ++ + KR S
Sbjct: 2187 SSSSSSSEESDSDEEEAQKRES 2208
>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
[Homo sapiens]
Length = 501
Score = 470 bits (1210), Expect = e-132
Identities = 247/512 (48%), Positives = 334/512 (65%), Gaps = 45/512 (8%)
Query: 2 NGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQ 61
+ HS E + S SQS+ + GS GSG GS S SSS+ S SQS S+S+S +GS+
Sbjct: 20 SSHSASEEA-SGSDSGSQSESEQGSDPGSGHGSESNSSSESSESQS-ESESES---AGSK 74
Query: 62 SESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSG 121
S+ ++E K D + W+ P + V+RS + Q S
Sbjct: 75 SQPVLPEAKEKPASKKERIADVKKMWEEYPDVYGVRRS-----------NRSRQEPSRFN 123
Query: 122 SEEDSSSSEDSDDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESD 181
+E++SS +S +R+ K E W+ S + G+ +ESE E++K
Sbjct: 124 IKEEASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPV-- 181
Query: 182 YEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVS 241
P+ V + + + K++ GK+ K+Q DSS+EDDD+++ KR +RR+A NVS
Sbjct: 182 --PRRTVPKPRVKKQPKTQRGKR-----KKQ-DSSDEDDDDDEAP--KRQTRRRAAKNVS 231
Query: 242 YKEDEEMKTDSDDLLEVCGEDVPQPEEEEFETIERFMDCRIGRKGATGATTTIYAVEADG 301
YKED++ +TDSDDL+E+ GE V + +++ ETIE+ +D R+G+KGATGA+TT+YA+EA+G
Sbjct: 232 YKEDDDFETDSDDLIEMTGEGVDE-QQDNSETIEKVLDSRLGKKGATGASTTVYAIEANG 290
Query: 302 DPNAGFEKNKEPGEIQYLIKWKGWSHIHNTWETEETLKQQNVRGMKKLDNYKKKDQETKR 361
DP+ F+ K+ GEIQYLIKWKGWS+IH+TWE+EE+L+QQ V+G+KKL+N+KKK+ E K+
Sbjct: 291 DPSGDFDTEKDEGEIQYLIKWKGWSYIHSTWESEESLQQQKVKGLKKLENFKKKEDEIKQ 350
Query: 362 WLKNASPEDVEYYNCQQELTDDLHKQYQIVERII---------------AHSNQKSAAGY 406
WL SPEDVEY+NCQQEL +L+KQYQIVER+I AHS + + +
Sbjct: 351 WLGKVSPEDVEYFNCQQELASELNKQYQIVERVIAVKTSKSTLGQTDFPAHSRKPAPSNE 410
Query: 407 PDYYCKWQGLPYSECSWEDGALISKKFQACIDEYFSRNQSKTTPFKDCKVLKQRPRFVAL 466
P+Y CKW GLPYSECSWED ALI KKFQ CID + SRN SKT P ++CK LKQRPRFVAL
Sbjct: 411 PEYLCKWMGLPYSECSWEDEALIGKKFQNCIDSFHSRNNSKTIPTRECKALKQRPRFVAL 470
Query: 467 KKQPSYIGGHEGLELRDYQLNGLNWLAHSWCK 498
KKQP+Y+GG E LELRDYQL GLNWLAHSWCK
Sbjct: 471 KKQPAYLGG-ENLELRDYQLEGLNWLAHSWCK 501
>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform b [Homo sapiens]
Length = 1042
Score = 446 bits (1148), Expect = e-125
Identities = 249/597 (41%), Positives = 372/597 (62%), Gaps = 30/597 (5%)
Query: 464 VALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYL 523
+ + PSY+ +G LRDYQ+ GLNWL + G + ILADEMGLGKT+QTI+ L YL
Sbjct: 169 IRFEVSPSYV---KGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYL 225
Query: 524 FHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKR 583
H + GP +++VP STL +W E + W + + ++GD ++R E +
Sbjct: 226 KHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGE--- 282
Query: 584 LKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITG 643
+++ +T+YE+++K+K+ +W ++ +DEAHR+KN+ S L + + +FKS +RLL+TG
Sbjct: 283 --WDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTG 340
Query: 644 TPLQNSLKELWSLLHFIMPEKFSSWEDFEE----EHGKGREYGYASLHKELEPFLLRRVK 699
TPLQN+L ELW+LL+F++P+ F+S +DF+ ++ G + LH L+PFLLRR+K
Sbjct: 341 TPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIK 400
Query: 700 KDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCC 759
DVEKSLP K E + + +S +Q+++Y IL ++ L+ K LNI+M+L+KCC
Sbjct: 401 TDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCC 460
Query: 760 NHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDI 819
NH YL + Y E H++ +SGK+++LDKLL +L+E+G+RVLIFSQM R+LDI
Sbjct: 461 NHPYLFDGAEPGPPYTTDE---HIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDI 517
Query: 820 LAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTV 879
L +Y +R + + RLDG E R++A++ FNA S F F+LSTRAGGLGINLASAD V
Sbjct: 518 LEDYCMWRGYEYCRLDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVV 577
Query: 880 VIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQR 939
+++DSDWNPQ DLQA RAHRIGQKK V ++RL+T +VEE I+ERA+ K+ LD +VIQ+
Sbjct: 578 ILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVIQQ 637
Query: 940 MDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRA 999
G+ + S KEE+ +++ GA +F +E E + DI IL+R
Sbjct: 638 ----GRLI------DQQSNKLAKEEMLQMIRHGATHVF---ASKESELTDEDITTILERG 684
Query: 1000 E--THENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRR 1054
E T E +G+ L F++ ++ + + E E+ E I +R R
Sbjct: 685 EKKTAEMNERLQKMGESSLRNFRMDIEQSLYKFEGEDYREKQKLGMVEWIEPPKRER 741
>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a1 isoform a [Homo sapiens]
Length = 1054
Score = 438 bits (1126), Expect = e-122
Identities = 249/609 (40%), Positives = 372/609 (61%), Gaps = 42/609 (6%)
Query: 464 VALKKQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYL 523
+ + PSY+ +G LRDYQ+ GLNWL + G + ILADEMGLGKT+QTI+ L YL
Sbjct: 169 IRFEVSPSYV---KGGPLRDYQIRGLNWLISLYENGVNGILADEMGLGKTLQTIALLGYL 225
Query: 524 FHEHQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKR 583
H + GP +++VP STL +W E + W + + ++GD ++R E +
Sbjct: 226 KHYRNIPGPHMVLVPKSTLHNWMNEFKRWVPSLRVICFVGDKDARAAFIRDEMMPGE--- 282
Query: 584 LKFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITG 643
+++ +T+YE+++K+K+ +W ++ +DEAHR+KN+ S L + + +FKS +RLL+TG
Sbjct: 283 --WDVCVTSYEMVIKEKSVFKKFHWRYLVIDEAHRIKNEKSKLSEIVREFKSTNRLLLTG 340
Query: 644 TPLQNSLKELWSLLHFIMPEKFSSWEDFEE----EHGKGREYGYASLHKELEPFLLRRVK 699
TPLQN+L ELW+LL+F++P+ F+S +DF+ ++ G + LH L+PFLLRR+K
Sbjct: 341 TPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKNCLGDQKLVERLHAVLKPFLLRRIK 400
Query: 700 KDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCC 759
DVEKSLP K E + + +S +Q+++Y IL ++ L+ K LNI+M+L+KCC
Sbjct: 401 TDVEKSLPPKKEIKIYLGLSKMQREWYTKILMKDIDVLNSSGKMDKMRLLNILMQLRKCC 460
Query: 760 NHCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDI 819
NH YL + Y E H++ +SGK+++LDKLL +L+E+G+RVLIFSQM R+LDI
Sbjct: 461 NHPYLFDGAEPGPPYTTDE---HIVSNSGKMVVLDKLLAKLKEQGSRVLIFSQMTRLLDI 517
Query: 820 LAEYLKYRQFPFQRLDGSIKGELR------------KQALDHFNAEGSEDFCFLLSTRAG 867
L +Y +R + + RLDG E R ++A++ FNA S F F+LSTRAG
Sbjct: 518 LEDYCMWRGYEYCRLDGQTPHEEREDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAG 577
Query: 868 GLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAK 927
GLGINLASAD V+++DSDWNPQ DLQA RAHRIGQKK V ++RL+T +VEE I+ERA+
Sbjct: 578 GLGINLASADVVILYDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAE 637
Query: 928 KKMVLDHLVIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEP 987
K+ LD +VIQ+ G+ + S KEE+ +++ GA +F +E E
Sbjct: 638 IKLRLDSIVIQQ----GRLI------DQQSNKLAKEEMLQMIRHGATHVF---ASKESEL 684
Query: 988 QEMDIDEILKRAE--THENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEE 1045
+ DI IL+R E T E +G+ L F++ ++ + + E E+ E
Sbjct: 685 TDEDITTILERGEKKTAEMNERLQKMGESSLRNFRMDIEQSLYKFEGEDYREKQKLGMVE 744
Query: 1046 IIPEDQRRR 1054
I +R R
Sbjct: 745 WIEPPKRER 753
>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a5 [Homo sapiens]
Length = 1052
Score = 431 bits (1107), Expect = e-120
Identities = 245/596 (41%), Positives = 364/596 (61%), Gaps = 40/596 (6%)
Query: 470 PSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQL 529
PSY+ + +LRDYQ+ GLNWL + G + ILADEMGLGKT+QTIS L Y+ H +
Sbjct: 172 PSYV---KWGKLRDYQVRGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNI 228
Query: 530 YGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSR-----NMIRTHEWTHHQTKRL 584
GP +++VP STL +W E + W + +V +GD R +++ EW
Sbjct: 229 PGPHMVLVPKSTLHNWMSEFKRWVPTLRSVCLIGDKEQRAAFVRDVLLPGEW-------- 280
Query: 585 KFNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGT 644
++ +T+YE+L+K+K+ NW ++ +DEAHR+KN+ S L + + +FK+ +RLL+TGT
Sbjct: 281 --DVCVTSYEMLIKEKSVFKKFNWRYLVIDEAHRIKNEKSKLSEIVREFKTTNRLLLTGT 338
Query: 645 PLQNSLKELWSLLHFIMPEKFSSWEDFEE----EHGKGREYGYASLHKELEPFLLRRVKK 700
PLQN+L ELWSLL+F++P+ F+S +DF+ + G + LH L PFLLRR+K
Sbjct: 339 PLQNNLHELWSLLNFLLPDVFNSADDFDSWFDTNNCLGDQKLVERLHMVLRPFLLRRIKA 398
Query: 701 DVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
DVEKSLP K E + + +S +Q+++Y IL ++ L+ K LNI+M+L+KCCN
Sbjct: 399 DVEKSLPPKKEVKIYVGLSKMQREWYTRILMKDIDILNSAGKMDKMRLLNILMQLRKCCN 458
Query: 761 HCYLIKPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDIL 820
H YL + Y HL+ +SGK+++LDKLL +L+E+G+RVLIFSQM R+LDIL
Sbjct: 459 HPYLFDGAEPGPPYTTD---MHLVTNSGKMVVLDKLLPKLKEQGSRVLIFSQMTRVLDIL 515
Query: 821 AEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVV 880
+Y +R + + RLDG + R+ +++ +N S F F+LSTRAGGLGINLA+AD V+
Sbjct: 516 EDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVI 575
Query: 881 IFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRM 940
++DSDWNPQ DLQA RAHRIGQ K V ++R +T +VEE I+ERA+ K+ LD +VIQ+
Sbjct: 576 LYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVIQQ- 634
Query: 941 DTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRA- 999
G+ V + K+E+ +++ GA +F +E E + DID IL+R
Sbjct: 635 ---GRLV------DQNLNKIGKDEMLQMIRHGATHVF---ASKESEITDEDIDGILERGA 682
Query: 1000 -ETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRR 1054
+T E +G+ L F + S++ + E E+ + E I +R R
Sbjct: 683 KKTAEMNEKLSKMGESSLRNFTMDTESSVYNFEGEDYREKQKIAFTEWIEPPKRER 738
>gi|148612870 chromodomain helicase DNA binding protein 1-like [Homo
sapiens]
Length = 897
Score = 410 bits (1055), Expect = e-114
Identities = 269/707 (38%), Positives = 389/707 (55%), Gaps = 55/707 (7%)
Query: 475 GHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFL 534
G G+ LR YQL G+NWLA + N CIL DEMGLGKT QTI+ YL GPFL
Sbjct: 40 GLTGIHLRSYQLEGVNWLAQRFHCQNGCILGDEMGLGKTCQTIALFIYLAGRLNDEGPFL 99
Query: 535 LVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYE 594
++ PLS L++W+ E+Q +A ++ V Y GD R ++ + +F++LLTTYE
Sbjct: 100 ILCPLSVLSNWKEEMQRFAPGLSCVTYAGDKEERACLQ-----QDLKQESRFHVLLTTYE 154
Query: 595 ILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELW 654
I LKD +FL W+ + VDEAHRLKN SLL+KTL +F LL+TGTP+QNSL+EL+
Sbjct: 155 ICLKDASFLKSFPWSVLVVDEAHRLKNQSSLLHKTLSEFSVVFSLLLTGTPIQNSLQELY 214
Query: 655 SLLHFIMPEKFSS---------WEDFEEEHGKGREYGYASLHKELEPFLLRRVKKDVEKS 705
SLL F+ P+ FS ++D E+E E LHK L+PFLLRRVK +V
Sbjct: 215 SLLSFVEPDLFSKEEVGDFIQRYQDIEKESESASE-----LHKLLQPFLLRRVKAEVATE 269
Query: 706 LPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMMELKKCCNHCYLI 765
LP K E ++ MSALQK+YYK IL ++ A + NI+ +L+KC +H YL
Sbjct: 270 LPKKTEVVIYHGMSALQKKYYKAILMKDLDAFENETAKKVK-LQNILSQLRKCVDHPYLF 328
Query: 766 KPPDNNEFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLK 825
+ F E HL +SGKL LLDKLL L G+RVL+FSQM +MLDIL +Y+
Sbjct: 329 DGVEPEPF----EVGDHLTEASGKLHLLDKLLAFLYSGGHRVLLFSQMTQMLDILQDYMD 384
Query: 826 YRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSD 885
YR + ++R+DGS++GE R A+ +F + F FLLSTRAGG+G+NL +ADTV+ DSD
Sbjct: 385 YRGYSYERVDGSVRGEERHLAIKNFGQQ--PIFVFLLSTRAGGVGMNLTAADTVIFVDSD 442
Query: 886 WNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTTGK 945
+NPQNDLQA ARAHRIGQ K V + RL+ + +VEE + +A K+ L +++I+ G
Sbjct: 443 FNPQNDLQAAARAHRIGQNKSVKVIRLIGRDTVEEIVYRKAASKLQLTNMIIE-----GG 497
Query: 946 TVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRAETHE-- 1003
P++ +LS ILKFG ++L EG + E+D++ IL + +
Sbjct: 498 HFTLGAQKPAADADL---QLSEILKFGLDKLLAS-EGSTMD--EIDLESILGETKDGQWV 551
Query: 1004 NEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEERQKE 1063
++ P G + + + D EP + + E + Q+ LE+ ++
Sbjct: 552 SDALPAAEGGSRDQEEGKNHMYLFEGKDYSKEPSKEDRKSFEQLVNLQKTLLEKASQEGR 611
Query: 1064 LEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRPRTIPRENI 1123
+RN + EG R R S + + + KR + + R + E
Sbjct: 612 --------SLRNKGSVLIPGLVEGSTKRKRVLSPEELED-RQKKRQEAAAKRRRLIEEKK 662
Query: 1124 KGFSDAEIRRFI-----KSYKKFGGPLERLDAIARDAELVDKSETDL 1165
+ +AE ++ + +Y+ F P E ++ D E ++S +L
Sbjct: 663 RQKEEAEHKKKMAWWESNNYQSFCLPSE--ESEPEDLENGEESSAEL 707
>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform F [Homo sapiens]
Length = 1613
Score = 403 bits (1035), Expect = e-112
Identities = 262/683 (38%), Positives = 359/683 (52%), Gaps = 71/683 (10%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQ+ GL WL + + ILADEMGLGKTIQTI+ + YL ++ GPFL++VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + V Y G +R Q + KFN+LLTTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G + LHK L PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQ+ Y K +L + K KG T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + F L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y YR F + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 936 VIQRMDTTGKTVLHTGSA------------------PSSST-----PFNKEELSAILKFG 972
VIQ K+ H A P T ++EE ++
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMD 1287
Query: 973 AEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDI 1032
+ +E +++P+ M+ DE+ + E LT +E + K+ + ++
Sbjct: 1288 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEE---EEKMFGRGSRHRKEV 1344
Query: 1033 ELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRS 1092
+ K W + I E +EEE RQK+ R R K+ S GS + +
Sbjct: 1345 DYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSS------RKR---KRDSDAGSSTPTTST 1395
Query: 1093 RRYSGSDSDSISEGKRPKKRGRP 1115
R D E K+ KKRGRP
Sbjct: 1396 R-----SRDKDDESKKQKKRGRP 1413
Score = 37.0 bits (84), Expect = 0.16
Identities = 24/96 (25%), Positives = 44/96 (45%), Gaps = 11/96 (11%)
Query: 137 SEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNR 196
+ V++K K++D G +SE EEE E+ + + K K+ RK + +
Sbjct: 1524 TSVRQKIEKEDD----------SEGEESEEEEEGEEEGSESESRSVKVKIKL-GRKEKAQ 1572
Query: 197 SKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSS 232
+ K G++ + R +DD EE+ + D+ S
Sbjct: 1573 DRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGS 1608
Score = 33.1 bits (74), Expect = 2.4
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 107 QQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK-----KHKDEDWQMSGSGSPSQ-- 159
+Q+ +++ + EE+ E S+ S VK K K K +D G PS+
Sbjct: 1527 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS 1586
Query: 160 ------SGSDSESEEEREKSSCDETE 179
S DSE E+E ++S E
Sbjct: 1587 RAKPVVSDDDSEEEQEEDRSGSGSEE 1612
Score = 32.7 bits (73), Expect = 3.1
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 13/101 (12%)
Query: 81 VDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVK 140
++G+ ++ S + +V S K +++ + + G EE S +S+ S +VK
Sbjct: 1507 LEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS----ESESRSVKVK 1562
Query: 141 RK---KHKDEDWQMSGSGSPSQSG------SDSESEEEREK 172
K K K +D G PS+ SD +SEEE+E+
Sbjct: 1563 IKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEE 1603
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 41 DGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSA 100
+ S S + + G E GS+SES S + K+ K D + + PS + +
Sbjct: 1533 EDDSEGEESEEEEEGEEEGSESESRS-VKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1591
Query: 101 ILKKQQQQQQQQQHQASSNSGSEED 125
+ +++Q++ S SGSEED
Sbjct: 1592 VSDDDSEEEQEEDR---SGSGSEED 1613
>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform E [Homo sapiens]
Length = 1614
Score = 403 bits (1035), Expect = e-112
Identities = 262/683 (38%), Positives = 359/683 (52%), Gaps = 71/683 (10%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQ+ GL WL + + ILADEMGLGKTIQTI+ + YL ++ GPFL++VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + V Y G +R Q + KFN+LLTTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G + LHK L PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQ+ Y K +L + K KG T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + F L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y YR F + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 936 VIQRMDTTGKTVLHTGSA------------------PSSST-----PFNKEELSAILKFG 972
VIQ K+ H A P T ++EE ++
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMD 1287
Query: 973 AEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDI 1032
+ +E +++P+ M+ DE+ + E LT +E + K+ + ++
Sbjct: 1288 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEE---EEKMFGRGSRHRKEV 1344
Query: 1033 ELEPERNSKNWEEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRS 1092
+ K W + I E +EEE RQK+ R R K+ S GS + +
Sbjct: 1345 DYSDSLTEKQWLKAIEEGTLEEIEEEVRQKKSS------RKR---KRDSDAGSSTPTTST 1395
Query: 1093 RRYSGSDSDSISEGKRPKKRGRP 1115
R D E K+ KKRGRP
Sbjct: 1396 R-----SRDKDDESKKQKKRGRP 1413
Score = 37.4 bits (85), Expect = 0.13
Identities = 49/245 (20%), Positives = 94/245 (38%), Gaps = 67/245 (27%)
Query: 44 SSQSGSSDSDSGSES---GSQSESESDTSRENKVQAKPPK-----------------VDG 83
SS+ DSD+GS + ++S + D S++ K + +PP VD
Sbjct: 1376 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1435
Query: 84 AEFWKSSPS--------------------ILAVQRSAILKKQQQQQQQQQHQASSNSGSE 123
+K S S +++ KK +++ + ++++ ++ +
Sbjct: 1436 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD 1495
Query: 124 -------------EDSSSSEDS---DDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESE 167
E S EDS + V++K K++D G +SE E
Sbjct: 1496 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD----------SEGEESEEE 1545
Query: 168 EEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDN 227
EE E+ + + K K+ RK + + + K G++ + R +DD EE+ +
Sbjct: 1546 EEGEEEGSESESRSVKVKIKL-GRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEE 1604
Query: 228 DKRSS 232
D+ S
Sbjct: 1605 DRSGS 1609
Score = 33.1 bits (74), Expect = 2.4
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 107 QQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK-----KHKDEDWQMSGSGSPSQ-- 159
+Q+ +++ + EE+ E S+ S VK K K K +D G PS+
Sbjct: 1528 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS 1587
Query: 160 ------SGSDSESEEEREKSSCDETE 179
S DSE E+E ++S E
Sbjct: 1588 RAKPVVSDDDSEEEQEEDRSGSGSEE 1613
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 41 DGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSA 100
+ S S + + G E GS+SES S + K+ K D + + PS + +
Sbjct: 1534 EDDSEGEESEEEEEGEEEGSESESRS-VKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1592
Query: 101 ILKKQQQQQQQQQHQASSNSGSEED 125
+ +++Q++ S SGSEED
Sbjct: 1593 VSDDDSEEEQEEDR---SGSGSEED 1614
>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform D [Homo sapiens]
Length = 1616
Score = 397 bits (1021), Expect = e-110
Identities = 262/686 (38%), Positives = 359/686 (52%), Gaps = 74/686 (10%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQ+ GL WL + + ILADEMGLGKTIQTI+ + YL ++ GPFL++VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + V Y G +R Q + KFN+LLTTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G + LHK L PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQ+ Y K +L + K KG T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + F L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y YR F + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 936 VIQRMDTTGKTVLHTGSA------------------PSSST-----PFNKEELSAILKFG 972
VIQ K+ H A P T ++EE ++
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMD 1287
Query: 973 AEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDI 1032
+ +E +++P+ M+ DE+ + E LT +E + K+ + ++
Sbjct: 1288 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEE---EEKMFGRGSRHRKEV 1344
Query: 1033 ELEPERNSKNW---EEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRR 1089
+ K W + I E +EEE RQK+ R R K+ S GS
Sbjct: 1345 DYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSS------RKR---KRDSDAGSSTPT 1395
Query: 1090 SRSRRYSGSDSDSISEGKRPKKRGRP 1115
+ +R D E K+ KKRGRP
Sbjct: 1396 TSTR-----SRDKDDESKKQKKRGRP 1416
Score = 37.0 bits (84), Expect = 0.16
Identities = 24/96 (25%), Positives = 44/96 (45%), Gaps = 11/96 (11%)
Query: 137 SEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNR 196
+ V++K K++D G +SE EEE E+ + + K K+ RK + +
Sbjct: 1527 TSVRQKIEKEDD----------SEGEESEEEEEGEEEGSESESRSVKVKIKL-GRKEKAQ 1575
Query: 197 SKSKNGKKILGQKKRQIDSSEEDDDEEDYDNDKRSS 232
+ K G++ + R +DD EE+ + D+ S
Sbjct: 1576 DRLKGGRRRPSRGSRAKPVVSDDDSEEEQEEDRSGS 1611
Score = 33.1 bits (74), Expect = 2.4
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 107 QQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK-----KHKDEDWQMSGSGSPSQ-- 159
+Q+ +++ + EE+ E S+ S VK K K K +D G PS+
Sbjct: 1530 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS 1589
Query: 160 ------SGSDSESEEEREKSSCDETE 179
S DSE E+E ++S E
Sbjct: 1590 RAKPVVSDDDSEEEQEEDRSGSGSEE 1615
Score = 32.7 bits (73), Expect = 3.1
Identities = 27/101 (26%), Positives = 47/101 (46%), Gaps = 13/101 (12%)
Query: 81 VDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVK 140
++G+ ++ S + +V S K +++ + + G EE S +S+ S +VK
Sbjct: 1510 LEGSLIYEDSIVLQSVFTSVRQKIEKEDDSEGEESEEEEEGEEEGS----ESESRSVKVK 1565
Query: 141 RK---KHKDEDWQMSGSGSPSQSG------SDSESEEEREK 172
K K K +D G PS+ SD +SEEE+E+
Sbjct: 1566 IKLGRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEE 1606
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 41 DGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSA 100
+ S S + + G E GS+SES S + K+ K D + + PS + +
Sbjct: 1536 EDDSEGEESEEEEEGEEEGSESESRS-VKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1594
Query: 101 ILKKQQQQQQQQQHQASSNSGSEED 125
+ +++Q++ S SGSEED
Sbjct: 1595 VSDDDSEEEQEEDR---SGSGSEED 1616
>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform C [Homo sapiens]
Length = 1617
Score = 397 bits (1021), Expect = e-110
Identities = 262/686 (38%), Positives = 359/686 (52%), Gaps = 74/686 (10%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQ+ GL WL + + ILADEMGLGKTIQTI+ + YL ++ GPFL++VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + V Y G +R Q + KFN+LLTTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G + LHK L PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQ+ Y K +L + K KG T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + F L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y YR F + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 936 VIQRMDTTGKTVLHTGSA------------------PSSST-----PFNKEELSAILKFG 972
VIQ K+ H A P T ++EE ++
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDEEEDEVPDDETVNQMIARHEEEFDLFMRMD 1287
Query: 973 AEELFKEPEGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDI 1032
+ +E +++P+ M+ DE+ + E LT +E + K+ + ++
Sbjct: 1288 LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEE---EEKMFGRGSRHRKEV 1344
Query: 1033 ELEPERNSKNW---EEIIPEDQRRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRR 1089
+ K W + I E +EEE RQK+ R R K+ S GS
Sbjct: 1345 DYSDSLTEKQWLKTLKAIEEGTLEEIEEEVRQKKSS------RKR---KRDSDAGSSTPT 1395
Query: 1090 SRSRRYSGSDSDSISEGKRPKKRGRP 1115
+ +R D E K+ KKRGRP
Sbjct: 1396 TSTR-----SRDKDDESKKQKKRGRP 1416
Score = 37.4 bits (85), Expect = 0.13
Identities = 49/245 (20%), Positives = 94/245 (38%), Gaps = 67/245 (27%)
Query: 44 SSQSGSSDSDSGSES---GSQSESESDTSRENKVQAKPPK-----------------VDG 83
SS+ DSD+GS + ++S + D S++ K + +PP VD
Sbjct: 1379 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1438
Query: 84 AEFWKSSPS--------------------ILAVQRSAILKKQQQQQQQQQHQASSNSGSE 123
+K S S +++ KK +++ + ++++ ++ +
Sbjct: 1439 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD 1498
Query: 124 -------------EDSSSSEDS---DDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESE 167
E S EDS + V++K K++D G +SE E
Sbjct: 1499 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD----------SEGEESEEE 1548
Query: 168 EEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDN 227
EE E+ + + K K+ RK + + + K G++ + R +DD EE+ +
Sbjct: 1549 EEGEEEGSESESRSVKVKIKL-GRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEE 1607
Query: 228 DKRSS 232
D+ S
Sbjct: 1608 DRSGS 1612
Score = 33.1 bits (74), Expect = 2.4
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 107 QQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK-----KHKDEDWQMSGSGSPSQ-- 159
+Q+ +++ + EE+ E S+ S VK K K K +D G PS+
Sbjct: 1531 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS 1590
Query: 160 ------SGSDSESEEEREKSSCDETE 179
S DSE E+E ++S E
Sbjct: 1591 RAKPVVSDDDSEEEQEEDRSGSGSEE 1616
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 41 DGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSA 100
+ S S + + G E GS+SES S + K+ K D + + PS + +
Sbjct: 1537 EDDSEGEESEEEEEGEEEGSESESRS-VKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1595
Query: 101 ILKKQQQQQQQQQHQASSNSGSEED 125
+ +++Q++ S SGSEED
Sbjct: 1596 VSDDDSEEEQEEDR---SGSGSEED 1617
>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 396 bits (1017), Expect = e-109
Identities = 264/716 (36%), Positives = 363/716 (50%), Gaps = 104/716 (14%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQ+ GL WL + + ILADEMGLGKTIQTI+ + YL ++ GPFL++VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + V Y G +R Q + KFN+LLTTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G + LHK L PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQ+ Y K +L + K KG T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + F L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y YR F + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 936 VIQ-----------------------------RMDTTGK---TVLHTGSAPSSSTP---- 959
VIQ R +TG + HT P+ P
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE 1287
Query: 960 --------------------FNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRA 999
++EE ++ + +E +++P+ M+ DE+
Sbjct: 1288 PPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWI 1347
Query: 1000 ETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEE 1059
+ E LT +E + K+ + +++ K W + I E +EEE
Sbjct: 1348 IKDDAEVERLTCEEE---EEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEV 1404
Query: 1060 RQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRP 1115
RQK+ R R K+ S GS + +R D E K+ KKRGRP
Sbjct: 1405 RQKKSS------RKR---KRDSDAGSSTPTTSTR-----SRDKDDESKKQKKRGRP 1446
Score = 37.4 bits (85), Expect = 0.13
Identities = 49/245 (20%), Positives = 94/245 (38%), Gaps = 67/245 (27%)
Query: 44 SSQSGSSDSDSGSES---GSQSESESDTSRENKVQAKPPK-----------------VDG 83
SS+ DSD+GS + ++S + D S++ K + +PP VD
Sbjct: 1409 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1468
Query: 84 AEFWKSSPS--------------------ILAVQRSAILKKQQQQQQQQQHQASSNSGSE 123
+K S S +++ KK +++ + ++++ ++ +
Sbjct: 1469 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD 1528
Query: 124 -------------EDSSSSEDS---DDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESE 167
E S EDS + V++K K++D G +SE E
Sbjct: 1529 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD----------SEGEESEEE 1578
Query: 168 EEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDN 227
EE E+ + + K K+ RK + + + K G++ + R +DD EE+ +
Sbjct: 1579 EEGEEEGSESESRSVKVKIKL-GRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEE 1637
Query: 228 DKRSS 232
D+ S
Sbjct: 1638 DRSGS 1642
Score = 33.1 bits (74), Expect = 2.4
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 107 QQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK-----KHKDEDWQMSGSGSPSQ-- 159
+Q+ +++ + EE+ E S+ S VK K K K +D G PS+
Sbjct: 1561 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS 1620
Query: 160 ------SGSDSESEEEREKSSCDETE 179
S DSE E+E ++S E
Sbjct: 1621 RAKPVVSDDDSEEEQEEDRSGSGSEE 1646
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 41 DGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSA 100
+ S S + + G E GS+SES S + K+ K D + + PS + +
Sbjct: 1567 EDDSEGEESEEEEEGEEEGSESESRS-VKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1625
Query: 101 ILKKQQQQQQQQQHQASSNSGSEED 125
+ +++Q++ S SGSEED
Sbjct: 1626 VSDDDSEEEQEEDR---SGSGSEED 1647
>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform B [Homo sapiens]
Length = 1647
Score = 396 bits (1017), Expect = e-109
Identities = 264/716 (36%), Positives = 363/716 (50%), Gaps = 104/716 (14%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQ+ GL WL + + ILADEMGLGKTIQTI+ + YL ++ GPFL++VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + V Y G +R Q + KFN+LLTTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G + LHK L PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQ+ Y K +L + K KG T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + F L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y YR F + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 936 VIQ-----------------------------RMDTTGK---TVLHTGSAPSSSTP---- 959
VIQ R +TG + HT P+ P
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE 1287
Query: 960 --------------------FNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEILKRA 999
++EE ++ + +E +++P+ M+ DE+
Sbjct: 1288 PPLKEEDEVPDDETVNQMIARHEEEFDLFMRMDLDRRREEARNPKRKPRLMEEDELPSWI 1347
Query: 1000 ETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQRRRLEEEE 1059
+ E LT +E + K+ + +++ K W + I E +EEE
Sbjct: 1348 IKDDAEVERLTCEEE---EEKMFGRGSRHRKEVDYSDSLTEKQWLKAIEEGTLEEIEEEV 1404
Query: 1060 RQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRPKKRGRP 1115
RQK+ R R K+ S GS + +R D E K+ KKRGRP
Sbjct: 1405 RQKKSS------RKR---KRDSDAGSSTPTTSTR-----SRDKDDESKKQKKRGRP 1446
Score = 37.4 bits (85), Expect = 0.13
Identities = 49/245 (20%), Positives = 94/245 (38%), Gaps = 67/245 (27%)
Query: 44 SSQSGSSDSDSGSES---GSQSESESDTSRENKVQAKPPK-----------------VDG 83
SS+ DSD+GS + ++S + D S++ K + +PP VD
Sbjct: 1409 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1468
Query: 84 AEFWKSSPS--------------------ILAVQRSAILKKQQQQQQQQQHQASSNSGSE 123
+K S S +++ KK +++ + ++++ ++ +
Sbjct: 1469 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD 1528
Query: 124 -------------EDSSSSEDS---DDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESE 167
E S EDS + V++K K++D G +SE E
Sbjct: 1529 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD----------SEGEESEEE 1578
Query: 168 EEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDN 227
EE E+ + + K K+ RK + + + K G++ + R +DD EE+ +
Sbjct: 1579 EEGEEEGSESESRSVKVKIKL-GRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEE 1637
Query: 228 DKRSS 232
D+ S
Sbjct: 1638 DRSGS 1642
Score = 33.1 bits (74), Expect = 2.4
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 107 QQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK-----KHKDEDWQMSGSGSPSQ-- 159
+Q+ +++ + EE+ E S+ S VK K K K +D G PS+
Sbjct: 1561 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS 1620
Query: 160 ------SGSDSESEEEREKSSCDETE 179
S DSE E+E ++S E
Sbjct: 1621 RAKPVVSDDDSEEEQEEDRSGSGSEE 1646
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 41 DGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSA 100
+ S S + + G E GS+SES S + K+ K D + + PS + +
Sbjct: 1567 EDDSEGEESEEEEEGEEEGSESESRS-VKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1625
Query: 101 ILKKQQQQQQQQQHQASSNSGSEED 125
+ +++Q++ S SGSEED
Sbjct: 1626 VSDDDSEEEQEEDR---SGSGSEED 1647
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 392 bits (1007), Expect = e-108
Identities = 265/695 (38%), Positives = 359/695 (51%), Gaps = 78/695 (11%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQL GL W+ + + ILADEMGLGKTIQTI+ + YL +L GP+L++VPLS
Sbjct: 724 LKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLS 783
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + + Y G R + Q + KFN+LLTTYE ++KDK
Sbjct: 784 TLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVP------QLRSGKFNVLLTTYEYIIKDK 837
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + R+L+TGTPLQN L ELW+LL+F
Sbjct: 838 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNF 897
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G LHK L PFLLRR+KK+VE
Sbjct: 898 LLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQ 957
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQK Y K IL + K KG +N +M+L+K CN
Sbjct: 958 LPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICN 1017
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + + N L R+SGK LLD++L +LR +RVL+F QM
Sbjct: 1018 HPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTS 1077
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y +R F + RLDG+ K E R L FN GS+ F FLLSTRAGGLG+NL +
Sbjct: 1078 LMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQA 1137
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTVVIFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1138 ADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1197
Query: 936 VIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEI 995
VIQ K SS+ + L AIL E E E +E E+ DE
Sbjct: 1198 VIQAGMFDQK----------SSSHERRAFLQAIL---------EHEEENEEEDEVPDDET 1238
Query: 996 LKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQ---- 1051
L + E L F MD D E RN K ++ ED+
Sbjct: 1239 LNQMIARREEEFDL--------------FMRMDMDR-RREDARNPKRKPRLMEEDELPSW 1283
Query: 1052 --RRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRP 1109
+ E E E EE + R + + ++ + + R + + + E R
Sbjct: 1284 IIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRL 1343
Query: 1110 KKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGP 1144
KKR R R + ++ K D E K+ K+ G P
Sbjct: 1344 KKRKRRRNVDKDPAK--EDVE-----KAKKRRGRP 1371
Score = 38.5 bits (88), Expect = 0.057
Identities = 33/168 (19%), Positives = 78/168 (46%), Gaps = 12/168 (7%)
Query: 97 QRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSS--SEVKRK-KHKDEDWQMSG 153
Q A +K+++++++++ + ++ G E D+SS S++ K H + + G
Sbjct: 549 QAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFG 608
Query: 154 SGSPSQSGSDSESE-----EEREKSSCDETESDYEPKNKVKSRKPQNRSKS----KNGKK 204
+P S D+ E E +S +E++SDYE +++ + Q + N ++
Sbjct: 609 PEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEE 668
Query: 205 ILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKEDEEMKTDS 252
+ + +QI + + D +++Y + Q+ V++ E ++ S
Sbjct: 669 VSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQS 716
Score = 35.0 bits (79), Expect = 0.63
Identities = 27/114 (23%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 81 VDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVK 140
++G++ ++ S + +V +SA +Q+ ++ ++ S EE+ E+S+ + VK
Sbjct: 1483 LEGSQIYEDSIVLQSVFKSA------RQKIAKEEESEDESNEEEEEEDEEESESEAKSVK 1536
Query: 141 ------------RKKHKDEDWQMSGSGSPSQSGSDS-ESEEEREKSSCDETESD 181
R K K + G P S DS E ++ERE+S T+ +
Sbjct: 1537 VKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1590
Score = 34.3 bits (77), Expect = 1.1
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Query: 159 QSGSDSESEEEREKSSCDETESDYEPKN---KVKSRKPQNRSKSK-NGKKILGQKKRQID 214
+ D +EEE E+ DE ES+ E K+ K+K K ++ + K GKK + K +
Sbjct: 1510 EESEDESNEEEEEE---DEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPV 1566
Query: 215 SSEEDDDEEDYDNDK 229
S+ D DEE + ++
Sbjct: 1567 VSDFDSDEEQDEREQ 1581
Score = 33.9 bits (76), Expect = 1.4
Identities = 26/134 (19%), Positives = 58/134 (43%), Gaps = 5/134 (3%)
Query: 135 SSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQ 194
++ E K+++ + + + + G S G D E +E + S + + KV
Sbjct: 552 AAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEA 611
Query: 195 NRSKSKNGKKILG---QKKRQIDSSEEDDDEEDYDNDKRSSRRQA--TVNVSYKEDEEMK 249
++ + + + + DS E D D E+ D ++ SSR++ + + +E +
Sbjct: 612 PKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSE 671
Query: 250 TDSDDLLEVCGEDV 263
D+ ++E +DV
Sbjct: 672 KDAKQIIETAKQDV 685
Score = 32.7 bits (73), Expect = 3.1
Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 11/104 (10%)
Query: 124 EDSSSSEDSDDSSSEVKRKKHK----DEDWQMSGSGSPSQSGSDSESEEEREKSSCDETE 179
E S EDS S K + K +E S + +SESE + K +
Sbjct: 1484 EGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNK 1543
Query: 180 SDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEE 223
D + ++K K +K NR K+K DS EE D+ E
Sbjct: 1544 KDDKGRDKGKGKKRPNRGKAK-------PVVSDFDSDEEQDERE 1580
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 392 bits (1007), Expect = e-108
Identities = 265/695 (38%), Positives = 359/695 (51%), Gaps = 78/695 (11%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQL GL W+ + + ILADEMGLGKTIQTI+ + YL +L GP+L++VPLS
Sbjct: 724 LKHYQLQGLEWMVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLS 783
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + + Y G R + Q + KFN+LLTTYE ++KDK
Sbjct: 784 TLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVP------QLRSGKFNVLLTTYEYIIKDK 837
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + R+L+TGTPLQN L ELW+LL+F
Sbjct: 838 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRILLTGTPLQNKLPELWALLNF 897
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G LHK L PFLLRR+KK+VE
Sbjct: 898 LLPTIFKSCSTFEQWFNAPFAMTGERVDLNEEETILIIRRLHKVLRPFLLRRLKKEVESQ 957
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQK Y K IL + K KG +N +M+L+K CN
Sbjct: 958 LPEKVEYVIKCDMSALQKILYRHMQAKGILLTDGSEKDKKGKGGAKTLMNTIMQLRKICN 1017
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + + N L R+SGK LLD++L +LR +RVL+F QM
Sbjct: 1018 HPYMFQHIEESFAEHLGYSNGVINGAELYRASGKFELLDRILPKLRATNHRVLLFCQMTS 1077
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y +R F + RLDG+ K E R L FN GS+ F FLLSTRAGGLG+NL +
Sbjct: 1078 LMTIMEDYFAFRNFLYLRLDGTTKSEDRAALLKKFNEPGSQYFIFLLSTRAGGLGLNLQA 1137
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTVVIFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1138 ADTVVIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1197
Query: 936 VIQRMDTTGKTVLHTGSAPSSSTPFNKEELSAILKFGAEELFKEPEGEEQEPQEMDIDEI 995
VIQ K SS+ + L AIL E E E +E E+ DE
Sbjct: 1198 VIQAGMFDQK----------SSSHERRAFLQAIL---------EHEEENEEEDEVPDDET 1238
Query: 996 LKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPERNSKNWEEIIPEDQ---- 1051
L + E L F MD D E RN K ++ ED+
Sbjct: 1239 LNQMIARREEEFDL--------------FMRMDMDR-RREDARNPKRKPRLMEEDELPSW 1283
Query: 1052 --RRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSRSRRYSGSDSDSISEGKRP 1109
+ E E E EE + R + + ++ + + R + + + E R
Sbjct: 1284 IIKDDAEVERLTCEEEEEKIFGRGSRQRRDVDYSDALTEKQWLRAIEDGNLEEMEEEVRL 1343
Query: 1110 KKRGRPRTIPRENIKGFSDAEIRRFIKSYKKFGGP 1144
KKR R R + ++ K D E K+ K+ G P
Sbjct: 1344 KKRKRRRNVDKDPAK--EDVE-----KAKKRRGRP 1371
Score = 38.5 bits (88), Expect = 0.057
Identities = 33/168 (19%), Positives = 78/168 (46%), Gaps = 12/168 (7%)
Query: 97 QRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSS--SEVKRK-KHKDEDWQMSG 153
Q A +K+++++++++ + ++ G E D+SS S++ K H + + G
Sbjct: 549 QAQAAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFG 608
Query: 154 SGSPSQSGSDSESE-----EEREKSSCDETESDYEPKNKVKSRKPQNRSKS----KNGKK 204
+P S D+ E E +S +E++SDYE +++ + Q + N ++
Sbjct: 609 PEAPKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEE 668
Query: 205 ILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKEDEEMKTDS 252
+ + +QI + + D +++Y + Q+ V++ E ++ S
Sbjct: 669 VSEKDAKQIIETAKQDVDDEYSMQYSARGSQSYYTVAHAISERVEKQS 716
Score = 35.0 bits (79), Expect = 0.63
Identities = 27/114 (23%), Positives = 52/114 (45%), Gaps = 19/114 (16%)
Query: 81 VDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVK 140
++G++ ++ S + +V +SA +Q+ ++ ++ S EE+ E+S+ + VK
Sbjct: 1465 LEGSQIYEDSIVLQSVFKSA------RQKIAKEEESEDESNEEEEEEDEEESESEAKSVK 1518
Query: 141 ------------RKKHKDEDWQMSGSGSPSQSGSDS-ESEEEREKSSCDETESD 181
R K K + G P S DS E ++ERE+S T+ +
Sbjct: 1519 VKIKLNKKDDKGRDKGKGKKRPNRGKAKPVVSDFDSDEEQDEREQSEGSGTDDE 1572
Score = 34.3 bits (77), Expect = 1.1
Identities = 24/75 (32%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Query: 159 QSGSDSESEEEREKSSCDETESDYEPKN---KVKSRKPQNRSKSK-NGKKILGQKKRQID 214
+ D +EEE E+ DE ES+ E K+ K+K K ++ + K GKK + K +
Sbjct: 1492 EESEDESNEEEEEE---DEEESESEAKSVKVKIKLNKKDDKGRDKGKGKKRPNRGKAKPV 1548
Query: 215 SSEEDDDEEDYDNDK 229
S+ D DEE + ++
Sbjct: 1549 VSDFDSDEEQDEREQ 1563
Score = 33.9 bits (76), Expect = 1.4
Identities = 26/134 (19%), Positives = 58/134 (43%), Gaps = 5/134 (3%)
Query: 135 SSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQ 194
++ E K+++ + + + + G S G D E +E + S + + KV
Sbjct: 552 AAKEKKKRRRRKKKAEENAEGGESALGPDGEPIDESSQMSDLPVKVTHTETGKVLFGPEA 611
Query: 195 NRSKSKNGKKILG---QKKRQIDSSEEDDDEEDYDNDKRSSRRQA--TVNVSYKEDEEMK 249
++ + + + + DS E D D E+ D ++ SSR++ + + +E +
Sbjct: 612 PKASQLDAWLEMNPGYEVAPRSDSEESDSDYEEEDEEEESSRQETEEKILLDPNSEEVSE 671
Query: 250 TDSDDLLEVCGEDV 263
D+ ++E +DV
Sbjct: 672 KDAKQIIETAKQDV 685
Score = 32.7 bits (73), Expect = 3.1
Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 11/104 (10%)
Query: 124 EDSSSSEDSDDSSSEVKRKKHK----DEDWQMSGSGSPSQSGSDSESEEEREKSSCDETE 179
E S EDS S K + K +E S + +SESE + K +
Sbjct: 1466 EGSQIYEDSIVLQSVFKSARQKIAKEEESEDESNEEEEEEDEEESESEAKSVKVKIKLNK 1525
Query: 180 SDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEE 223
D + ++K K +K NR K+K DS EE D+ E
Sbjct: 1526 KDDKGRDKGKGKKRPNRGKAK-------PVVSDFDSDEEQDERE 1562
>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a4 isoform A [Homo sapiens]
Length = 1679
Score = 384 bits (987), Expect = e-106
Identities = 255/668 (38%), Positives = 353/668 (52%), Gaps = 74/668 (11%)
Query: 481 LRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEHQLYGPFLLVVPLS 540
L+ YQ+ GL WL + + ILADEMGLGKTIQTI+ + YL ++ GPFL++VPLS
Sbjct: 754 LKQYQIKGLEWLVSLYNNNLNGILADEMGLGKTIQTIALITYLMEHKRINGPFLIIVPLS 813
Query: 541 TLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFNILLTTYEILLKDK 600
TL++W E WA + V Y G +R Q + KFN+LLTTYE ++KDK
Sbjct: 814 TLSNWAYEFDKWAPSVVKVSYKGSPAARRAFVP------QLRSGKFNVLLTTYEYIIKDK 867
Query: 601 AFLGGLNWAFIGVDEAHRLKNDDSLLYKTL-IDFKSNHRLLITGTPLQNSLKELWSLLHF 659
L + W ++ VDE HR+KN L + L + + RLL+TGTPLQN L ELW+LL+F
Sbjct: 868 HILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNF 927
Query: 660 IMPEKFSSWEDFEEEHGK-----GREYGYAS---------LHKELEPFLLRRVKKDVEKS 705
++P F S FE+ G + LHK L PFLLRR+KK+VE
Sbjct: 928 LLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEETILIIRRLHKVLRPFLLRRLKKEVEAQ 987
Query: 706 LPAKVEQILRMEMSALQKQYY-----KWILTRNYKALSKGSKGSTSGFLNIMMELKKCCN 760
LP KVE +++ +MSALQ+ Y K +L + K KG T +N +M+L+K CN
Sbjct: 988 LPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTDGSEKDKKGKGGTKTLMNTIMQLRKICN 1047
Query: 761 HCYLIKPPDNN-----EFYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVR 815
H Y+ + + + F L R+SGK LLD++L +LR ++VL+F QM
Sbjct: 1048 HPYMFQHIEESFSEHLGFTGGIVQGLDLYRASGKFELLDRILPKLRATNHKVLLFCQMTS 1107
Query: 816 MLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLAS 875
++ I+ +Y YR F + RLDG+ K E R L FN GSE F FLLSTRAGGLG+NL S
Sbjct: 1108 LMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQS 1167
Query: 876 ADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHL 935
ADTV+IFDSDWNP DLQAQ RAHRIGQ+ +V + RL T SVEE IL AK K+ +D
Sbjct: 1168 ADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQK 1227
Query: 936 VIQRMDTTGKTVLHTGSAPSSSTPFNKEE----------------LSAILKFGAEELFKE 979
VIQ K+ H A + ++E+ +A G +E
Sbjct: 1228 VIQAGMFDQKSSSHERRAFLQAILEHEEQDESRHCSTGSGSASFAHTAPPPAGVNPDLEE 1287
Query: 980 P--EGEEQEPQEMDIDEILKRAETHENEPGPLTVGDELLSQFKVANFSNMDEDDIELEPE 1037
P + E++ P + +++++ R HE E F + F MD D E
Sbjct: 1288 PPLKEEDEVPDDETVNQMIAR---HEEE-------------FDL--FMRMDLDR-RREEA 1328
Query: 1038 RNSKNWEEIIPEDQ------RRRLEEEERQKELEEIYMLPRMRNCAKQISFNGSEGRRSR 1091
RN K ++ ED+ + E E E EE M R K++ ++ S +
Sbjct: 1329 RNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYSDSLTEKQW 1388
Query: 1092 SRRYSGSD 1099
++ +G D
Sbjct: 1389 LKKITGKD 1396
Score = 37.4 bits (85), Expect = 0.13
Identities = 49/245 (20%), Positives = 94/245 (38%), Gaps = 67/245 (27%)
Query: 44 SSQSGSSDSDSGSES---GSQSESESDTSRENKVQAKPPK-----------------VDG 83
SS+ DSD+GS + ++S + D S++ K + +PP VD
Sbjct: 1441 SSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQKKRGRPPAEKLSPNPPNLTKKMKKIVDA 1500
Query: 84 AEFWKSSPS--------------------ILAVQRSAILKKQQQQQQQQQHQASSNSGSE 123
+K S S +++ KK +++ + ++++ ++ +
Sbjct: 1501 VIKYKDSSSGRQLSEVFIQLPSRKELPEYYELIRKPVDFKKIKERIRNHKYRSLNDLEKD 1560
Query: 124 -------------EDSSSSEDS---DDSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSESE 167
E S EDS + V++K K++D G +SE E
Sbjct: 1561 VMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSVRQKIEKEDD----------SEGEESEEE 1610
Query: 168 EEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNGKKILGQKKRQIDSSEEDDDEEDYDN 227
EE E+ + + K K+ RK + + + K G++ + R +DD EE+ +
Sbjct: 1611 EEGEEEGSESESRSVKVKIKL-GRKEKAQDRLKGGRRRPSRGSRAKPVVSDDDSEEEQEE 1669
Query: 228 DKRSS 232
D+ S
Sbjct: 1670 DRSGS 1674
Score = 33.1 bits (74), Expect = 2.4
Identities = 23/86 (26%), Positives = 36/86 (41%), Gaps = 13/86 (15%)
Query: 107 QQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK-----KHKDEDWQMSGSGSPSQ-- 159
+Q+ +++ + EE+ E S+ S VK K K K +D G PS+
Sbjct: 1593 RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS 1652
Query: 160 ------SGSDSESEEEREKSSCDETE 179
S DSE E+E ++S E
Sbjct: 1653 RAKPVVSDDDSEEEQEEDRSGSGSEE 1678
Score = 31.6 bits (70), Expect = 6.9
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%)
Query: 41 DGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSA 100
+ S S + + G E GS+SES S + K+ K D + + PS + +
Sbjct: 1599 EDDSEGEESEEEEEGEEEGSESESRS-VKVKIKLGRKEKAQDRLKGGRRRPSRGSRAKPV 1657
Query: 101 ILKKQQQQQQQQQHQASSNSGSEED 125
+ +++Q++ S SGSEED
Sbjct: 1658 VSDDDSEEEQEEDR---SGSGSEED 1679
>gi|190358536 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 298 bits (763), Expect = 3e-80
Identities = 190/523 (36%), Positives = 282/523 (53%), Gaps = 65/523 (12%)
Query: 468 KQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEH 527
+QPS + ++ L L+ YQ GLNWLA G + ILADEMGLGKTIQ I+FL YL+ E
Sbjct: 486 EQPSIL--NQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEG 543
Query: 528 QLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFN 587
GP L+VVP ST+ +W RE+ W + + Y G R IR + + ++ +N
Sbjct: 544 N-NGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYED----YN 598
Query: 588 ILLTTYEILLK---DKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGT 644
+++TTY + D++ L + DE H LKN S+ Y+ L+ +N+RLL+TGT
Sbjct: 599 VIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGT 658
Query: 645 PLQNSLKELWSLLHFIMPEKFSSWED-----------FEEEHGKGREYGYASLHKELEPF 693
P+QN+L EL SLL+F+MP FSS +E + A + ++PF
Sbjct: 659 PVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPF 718
Query: 694 LLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMM 753
+LRRVK++V K LP K ++I MS Q+Q Y + R K+++ + N+MM
Sbjct: 719 ILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMM 778
Query: 754 ELKKCCNHCYL-----------------IKPPDNNE------------------------ 772
+L+K NH L +K P + E
Sbjct: 779 QLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQ 838
Query: 773 --FYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFP 830
N + LI SGK +L +L L+++G+RV++FSQ MLDIL LK+ Q
Sbjct: 839 YRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHR 898
Query: 831 FQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQN 890
+ RLDG + R +D FN + + F FLLST+AGGLGINL SA+ V++ D D NP N
Sbjct: 899 YLRLDGKTQISERIHLIDEFNTD-MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYN 957
Query: 891 DLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLD 933
D QA+ R HR+GQ K+V + +L+++G++EE +L+ ++K+ L+
Sbjct: 958 DKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE 1000
>gi|190358532 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform a [Homo sapiens]
Length = 1028
Score = 298 bits (763), Expect = 3e-80
Identities = 190/523 (36%), Positives = 282/523 (53%), Gaps = 65/523 (12%)
Query: 468 KQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEH 527
+QPS + ++ L L+ YQ GLNWLA G + ILADEMGLGKTIQ I+FL YL+ E
Sbjct: 486 EQPSIL--NQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEG 543
Query: 528 QLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFN 587
GP L+VVP ST+ +W RE+ W + + Y G R IR + + ++ +N
Sbjct: 544 N-NGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYED----YN 598
Query: 588 ILLTTYEILLK---DKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGT 644
+++TTY + D++ L + DE H LKN S+ Y+ L+ +N+RLL+TGT
Sbjct: 599 VIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGT 658
Query: 645 PLQNSLKELWSLLHFIMPEKFSSWED-----------FEEEHGKGREYGYASLHKELEPF 693
P+QN+L EL SLL+F+MP FSS +E + A + ++PF
Sbjct: 659 PVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPF 718
Query: 694 LLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMM 753
+LRRVK++V K LP K ++I MS Q+Q Y + R K+++ + N+MM
Sbjct: 719 ILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMM 778
Query: 754 ELKKCCNHCYL-----------------IKPPDNNE------------------------ 772
+L+K NH L +K P + E
Sbjct: 779 QLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQ 838
Query: 773 --FYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFP 830
N + LI SGK +L +L L+++G+RV++FSQ MLDIL LK+ Q
Sbjct: 839 YRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHR 898
Query: 831 FQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQN 890
+ RLDG + R +D FN + + F FLLST+AGGLGINL SA+ V++ D D NP N
Sbjct: 899 YLRLDGKTQISERIHLIDEFNTD-MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYN 957
Query: 891 DLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLD 933
D QA+ R HR+GQ K+V + +L+++G++EE +L+ ++K+ L+
Sbjct: 958 DKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE 1000
>gi|190358534 SWI/SNF-related, matrix-associated actin-dependent
regulator of chromatin, subfamily a, containing DEAD/H
box 1 isoform b [Homo sapiens]
Length = 1026
Score = 297 bits (761), Expect = 5e-80
Identities = 191/523 (36%), Positives = 283/523 (54%), Gaps = 67/523 (12%)
Query: 468 KQPSYIGGHEGLELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFLNYLFHEH 527
+QPS + ++ L L+ YQ GLNWLA G + ILADEMGLGKTIQ I+FL YL+ E
Sbjct: 486 EQPSIL--NQSLSLKPYQKVGLNWLALVHKHGLNGILADEMGLGKTIQAIAFLAYLYQEG 543
Query: 528 QLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLKFN 587
GP L+VVP ST+ +W RE+ W + + Y G R IR + + ++ +N
Sbjct: 544 N-NGPHLIVVPASTIDNWLREVNLWCPTLKVLCYYGSQEERKQIRFNIHSRYED----YN 598
Query: 588 ILLTTYEILLK---DKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGT 644
+++TTY + D++ L + DE H LKN S+ Y+ L+ +N+RLL+TGT
Sbjct: 599 VIVTTYNCAISSSDDRSLFRRLKLNYAIFDEGHMLKNMGSIRYQHLMTINANNRLLLTGT 658
Query: 645 PLQNSLKELWSLLHFIMPEKFSSWED-----------FEEEHGKGREYGYASLHKELEPF 693
P+QN+L EL SLL+F+MP FSS +E + A + ++PF
Sbjct: 659 PVQNNLLELMSLLNFVMPHMFSSSTSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPF 718
Query: 694 LLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKALSKGSKGSTSGFLNIMM 753
+LRRVK++V K LP K ++I MS Q+Q Y + R K+++ K + N+MM
Sbjct: 719 ILRRVKEEVLKQLPPKKDRIELCAMSEKQEQLYLGLFNRLKKSINNLEKNTE--MCNVMM 776
Query: 754 ELKKCCNHCYL-----------------IKPPDNNE------------------------ 772
+L+K NH L +K P + E
Sbjct: 777 QLRKMANHPLLHRQYYTAEKLKEMSQLMLKEPTHCEANPDLIFEDMEVMTDFELHVLCKQ 836
Query: 773 --FYNKQEALQHLIRSSGKLILLDKLLIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFP 830
N + LI SGK +L +L L+++G+RV++FSQ MLDIL LK+ Q
Sbjct: 837 YRHINNFQLDMDLILDSGKFRVLGCILSELKQKGDRVVLFSQFTMMLDILEVLLKHHQHR 896
Query: 831 FQRLDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQN 890
+ RLDG + R +D FN + + F FLLST+AGGLGINL SA+ V++ D D NP N
Sbjct: 897 YLRLDGKTQISERIHLIDEFNTD-MDIFVFLLSTKAGGLGINLTSANVVILHDIDCNPYN 955
Query: 891 DLQAQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLD 933
D QA+ R HR+GQ K+V + +L+++G++EE +L+ ++K+ L+
Sbjct: 956 DKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLE 998
>gi|4557565 excision repair cross-complementing rodent repair
deficiency, complementation group 6 [Homo sapiens]
Length = 1493
Score = 256 bits (655), Expect = 1e-67
Identities = 167/500 (33%), Positives = 260/500 (52%), Gaps = 58/500 (11%)
Query: 480 ELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFL-------------NYLFHE 526
+L YQ G+ WL C+ IL DEMGLGKTIQ I+FL NY F
Sbjct: 506 KLFKYQQTGVRWLWELHCQQAGGILGDEMGLGKTIQIIAFLAGLSYSKIRTRGSNYRFEG 565
Query: 527 HQLYGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQTKRLK- 585
GP ++V P + + W +E TW + + T +TH + K ++
Sbjct: 566 ---LGPTVIVCPTTVMHQWVKEFHTWWPPFRVAI---------LHETGSYTHKKEKLIRD 613
Query: 586 ----FNILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLI 641
IL+T+Y + + + +W ++ +DE H+++N ++ + F++ HR+++
Sbjct: 614 VAHCHGILITSYSYIRLMQDDISRYDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIIL 673
Query: 642 TGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGREYGYAS---------------- 685
+G+P+QN+L+ELWSL FI P K + F E+ G S
Sbjct: 674 SGSPMQNNLRELWSLFDFIFPGKLGTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACV 733
Query: 686 LHKELEPFLLRRVKKDVEKSL--PAKVEQILRMEMSALQ-KQYYKWILTRNYKALSKGSK 742
L + P+LLRR+K DV+ SL P K EQ+L ++ Q K Y ++ ++ + G
Sbjct: 734 LRDTINPYLLRRMKSDVKMSLSLPDKNEQVLFCRLTDEQHKVYQNFVDSKEVYRILNGEM 793
Query: 743 GSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQH----LIRSSGKLILLDKLLI 798
SG ++ L+K CNH L N + L+ + SGK+I+++ LL
Sbjct: 794 QIFSG----LIALRKICNHPDLFSGGPKNLKGLPDDELEEDQFGYWKRSGKMIVVESLLK 849
Query: 799 RLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSIKGELRKQALDHFNAEGSEDF 858
++G RVL+FSQ +MLDIL +L+ +++ + ++DG+ R+ + +N E + F
Sbjct: 850 IWHKQGQRVLLFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYN-EDTSIF 908
Query: 859 CFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGSV 918
FLL+TR GGLG+NL A+ VVI+D DWNP D QA+ RA RIGQKKQV +YRL+T G++
Sbjct: 909 VFLLTTRVGGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTI 968
Query: 919 EEDILERAKKKMVLDHLVIQ 938
EE I R K L + V++
Sbjct: 969 EEKIYHRQIFKQFLTNRVLK 988
>gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription
factor-associated, 170kDa [Homo sapiens]
Length = 1849
Score = 248 bits (634), Expect = 3e-65
Identities = 181/530 (34%), Positives = 264/530 (49%), Gaps = 75/530 (14%)
Query: 480 ELRDYQLNGLNWLAHSWCKGNSCILADEMGLGKTIQTISFL-NYLFHEHQLYG------- 531
ELR YQ +G+NWLA IL D+MGLGKT+Q+I L H Q Y
Sbjct: 1265 ELRKYQQDGVNWLAFLNKYKLHGILCDDMGLGKTLQSICILAGDHCHRAQEYARSKLAEC 1324
Query: 532 ---PFLLVVPLSTLTSWQREIQTWASQ--MNAVVYLGDINSRNMIRTHEWTHHQTKRLKF 586
P L+V P + W E+ + S+ +N + Y G R ++ HQ KR
Sbjct: 1325 MPLPSLVVCPPTLTGHWVDEVGKFCSREYLNPLHYTGPPTERIRLQ------HQVKR--H 1376
Query: 587 NILLTTYEILLKDKAFLGGLNWAFIGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPL 646
N+++ +Y+++ D F + + + +DE H +KN + L K + +N+R++++GTP+
Sbjct: 1377 NLIVASYDVVRNDIDFFRNIKFNYCILDEGHVIKNGKTKLSKAVKQLTANYRIILSGTPI 1436
Query: 647 QNSLKELWSLLHFIMPEKFSSWEDFEEEHGKG-------------REYGYAS---LHKEL 690
QN++ ELWSL F+MP + F +GK +E G + LH+++
Sbjct: 1437 QNNVLELWSLFDFLMPGFLGTERQFAARYGKPILASRDARSSSREQEAGVLAMDALHRQV 1496
Query: 691 EPFLLRRVKKDVEKSLPAKVEQILRMEMSALQKQYYKWILTRNYKA-------------- 736
PFLLRR+K+DV + LP K+ Q +S LQ Q Y+ K
Sbjct: 1497 LPFLLRRMKEDVLQDLPPKIIQDYYCTLSPLQVQLYEDFAKSRAKCDVDETVSSATLSEE 1556
Query: 737 LSKGSKGSTSGFLNIMMELKKCCNHCYLIKPPDNNEFYNKQEALQ------HLIRSSGKL 790
K +T + L+K CNH L+ P + EF E L H I+ + KL
Sbjct: 1557 TEKPKLKATGHVFQALQYLRKLCNHPALVLTPQHPEFKTTAEKLAVQNSSLHDIQHAPKL 1616
Query: 791 ILLDKLLI-------RLRERG-------NRVLIFSQMVRMLDILAEYLKYRQFP---FQR 833
L +LL+ E G +R+LIF Q+ MLDI+ L P + R
Sbjct: 1617 SALKQLLLDCGLGNGSTSESGTESVVAQHRILIFCQLKSMLDIVEHDLLKPHLPSVTYLR 1676
Query: 834 LDGSIKGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQ 893
LDGSI R + FN + S D LL+T GGLG+NL ADTVV + DWNP DLQ
Sbjct: 1677 LDGSIPPGQRHSIVSRFNNDPSIDV-LLLTTHVGGLGLNLTGADTVVFVEHDWNPMRDLQ 1735
Query: 894 AQARAHRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVIQRMDTT 943
A RAHRIGQK+ VN+YRL+T+G++EE I+ K KM + + VI + +++
Sbjct: 1736 AMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANTVISQENSS 1785
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 69,978,851
Number of Sequences: 37866
Number of extensions: 3495154
Number of successful extensions: 45142
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 586
Number of HSP's successfully gapped in prelim test: 1100
Number of HSP's that attempted gapping in prelim test: 20666
Number of HSP's gapped (non-prelim): 15498
length of query: 1710
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1594
effective length of database: 13,855,062
effective search space: 22084968828
effective search space used: 22084968828
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.