Guide to the Human Genome
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Search of human proteins with 68160937

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68160937 tripartite motif-containing 25 [Homo sapiens]
         (630 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68160937 tripartite motif-containing 25 [Homo sapiens]            1301   0.0  
gi|54792146 tripartite motif-containing 47 [Homo sapiens]             187   2e-47
gi|48255913 tripartite motif-containing 16 [Homo sapiens]             155   1e-37
gi|148833499 midline 1 [Homo sapiens]                                 152   9e-37
gi|4557753 midline 1 [Homo sapiens]                                   152   9e-37
gi|15451852 midline 1 [Homo sapiens]                                  152   9e-37
gi|223890259 midline 2 isoform 2 [Homo sapiens]                       144   3e-34
gi|223890257 midline 2 isoform 1 [Homo sapiens]                       140   3e-33
gi|38679905 tripartite motif-containing 65 [Homo sapiens]             132   1e-30
gi|148596968 tripartite motif-containing 8 [Homo sapiens]             126   5e-29
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   125   9e-29
gi|17402909 tripartite motif protein TRIM29 [Homo sapiens]            115   1e-25
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...   103   5e-22
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...   103   5e-22
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...   103   5e-22
gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]           91   4e-18
gi|22749269 ring finger protein 129 [Homo sapiens]                     86   1e-16
gi|89886468 fibronectin type III and SPRY domain containing 1-li...    82   1e-15
gi|223718222 fibronectin type III and SPRY domain containing 1-l...    82   1e-15
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...    81   3e-15
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]     81   3e-15
gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo ...    80   4e-15
gi|27734883 tripartite motif family-like 2 [Homo sapiens]              80   6e-15
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]    79   1e-14
gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]     79   2e-14
gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]     79   2e-14
gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]     79   2e-14
gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]     79   2e-14
gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo...    78   3e-14
gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo ...    78   3e-14

>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score = 1301 bits (3367), Expect = 0.0
 Identities = 630/630 (100%), Positives = 630/630 (100%)

Query: 1   MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQAR 60
           MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQAR
Sbjct: 1   MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQAR 60

Query: 61  PQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCL 120
           PQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCL
Sbjct: 61  PQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCL 120

Query: 121 VCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL 180
           VCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL
Sbjct: 121 VCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL 180

Query: 181 VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ 240
           VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ
Sbjct: 181 VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ 240

Query: 241 LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLT 300
           LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLT
Sbjct: 241 LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLT 300

Query: 301 KRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTP 360
           KRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTP
Sbjct: 301 KRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTP 360

Query: 361 SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL 420
           SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL
Sbjct: 361 SSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGL 420

Query: 421 EAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVAS 480
           EAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVAS
Sbjct: 421 EAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVAS 480

Query: 481 VAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPES 540
           VAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPES
Sbjct: 481 VAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPES 540

Query: 541 RLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM 600
           RLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM
Sbjct: 541 RLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM 600

Query: 601 YKFRVDFTEALYPAFWVFSAGATLSICSPK 630
           YKFRVDFTEALYPAFWVFSAGATLSICSPK
Sbjct: 601 YKFRVDFTEALYPAFWVFSAGATLSICSPK 630


>gi|54792146 tripartite motif-containing 47 [Homo sapiens]
          Length = 638

 Score =  187 bits (476), Expect = 2e-47
 Identities = 186/675 (27%), Positives = 275/675 (40%), Gaps = 118/675 (17%)

Query: 12  SCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYL--------CPQCRAVYQARPQL 63
           SC ICLEP +EPVT PCGHNFC +CL   W  +G+           CP C+  +    QL
Sbjct: 8   SCPICLEPLREPVTLPCGHNFCLACLGALWPHRGASGAGGPGGAARCPLCQEPFPDGLQL 67

Query: 64  HKNTVLCNVVEQFLQAD-----------LAREPPADVWTP----PARASAPSP----NAQ 104
            KN  L  ++ Q  Q             LA EP A    P    P+   AP P       
Sbjct: 68  RKNHTLSELL-QLRQGSGPGSGPGPAPALAPEPSAPSALPSVPEPSAPCAPEPWPAGEEP 126

Query: 105 VACDHCLKEAAVK---TCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHN 161
           V CD C + AA+    +CL C+ASFC  HL PH  SPA + H L PP+R L    C +H 
Sbjct: 127 VRCDACPEGAALPAALSCLSCLASFCPAHLGPHERSPALRGHRLVPPLRRLEESLCPRHL 186

Query: 162 RLREFFCPEHSECICHICLV-EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRAL 220
           R  E +C     C+C  C   EH+      L Q  A  EA     L+ +  +++     +
Sbjct: 187 RPLERYCRAERVCLCEACAAQEHRGHELVPLEQERALQEAEQSKVLSAVEDRMDELGAGI 246

Query: 221 DDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQI 280
              R     ++  A  + E++ + + +  A L   +T     I+E E  +  +     + 
Sbjct: 247 AQSRRTVALIKSAAVAERERVSRLFADAAAALQGFQTQVLGFIEEGEAAMLGRSQGDLRR 306

Query: 281 LLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQS 340
             +++S +   ++ + Q + + D   FL                              Q 
Sbjct: 307 QEEQRSRLSRARQNLSQ-VPEADSVSFL------------------------------QE 335

Query: 341 TIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALP 400
            + L+  L+   G      P  G P E     + ++ R V+ +              A  
Sbjct: 336 LLALRLALEDGCG------PGPGPPRELSFTKSSQAVRAVRDML-----------AVACV 378

Query: 401 SKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVI 460
           ++      P    D  Q  L++ A A      ST+L    LE+     R   L++   V 
Sbjct: 379 NQWEQLRGPGGNEDGPQK-LDSEADAEPQDLESTNL----LES--EAPRDYFLKFAYIVD 431

Query: 461 LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQK 520
           LD +TA   + L     V  V   P NY   P RFT+C QVLG     +G +YWEVE+ +
Sbjct: 432 LDSDTADKFLQLFGTKGVKRVL-CPINYPLSPTRFTHCEQVLGEGALDRGTYYWEVEIIE 490

Query: 521 NNFCGVGICYGSMNRQGP--ESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVG 578
             +  +G+     + Q P    RLGRN+ S C++W     S W + +E  LP   +  VG
Sbjct: 491 G-WVSMGVMAEDFSPQEPYDRGRLGRNAHSCCLQWNGRSFSVWFHGLEAPLPHPFSPTVG 549

Query: 579 VLLNCDHGFVIFFAVAD-KVHLM--------------------YKFRVD------FTEAL 611
           V L      + F+AV D K+ L+                    ++ R+D      FT  L
Sbjct: 550 VCLEYADRALAFYAVRDGKMSLLRRLKASRPRRGGIPASPIDPFQSRLDSHFAGLFTHRL 609

Query: 612 YPAFWVFSAGATLSI 626
            PAF++ S  A L I
Sbjct: 610 KPAFFLESVDAHLQI 624


>gi|48255913 tripartite motif-containing 16 [Homo sapiens]
          Length = 564

 Score =  155 bits (392), Expect = 1e-37
 Identities = 131/522 (25%), Positives = 225/522 (43%), Gaps = 67/522 (12%)

Query: 104 QVACDHCLKEA----AVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQ 159
           +V CD CL +     AVK+CL CM ++C+EHLQPH  +   Q H L  PV+D   R C  
Sbjct: 74  EVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPA 133

Query: 160 HNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRA 219
           H+     FC    +CIC  C  EH   +  SL  A  D EA L+     +  ++     A
Sbjct: 134 HHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENA 193

Query: 220 LDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQ 279
           +  ++  Q+ V ++ +      + ++ E+ A +  ++      ++E+E+   S+ + I  
Sbjct: 194 ISRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKA 253

Query: 280 ILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQ 339
            L  + +E++  K+E+E+     +  +FLE+  K +  +T+ +  P V            
Sbjct: 254 HLEYRSAEMEKSKQELERMAAISNTVQFLEEYCKFK--NTEDITFPSVY----------- 300

Query: 340 STIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPAL 399
             + LK++L      + E T                    V  +   E   KK       
Sbjct: 301 --VGLKDKLSGIRKVITEST--------------------VHLIQLLENYKKK------- 331

Query: 400 PSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKV 459
              L  F   E+     Q       K  +S P  ++             R + L+Y   +
Sbjct: 332 ---LQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPST-------------REQFLQYAYDI 375

Query: 460 ILDYNTAHNKVALSE-CYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518
             D +TAH  + L E    V +       Y   P RF +  QVL         +Y+EVE+
Sbjct: 376 TFDPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEI 435

Query: 519 QKNNFCGVGICYGSMNRQGPE--SRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATR 576
                  VG+    ++R+G E  S +  N+ SW ++W   + +AW++++E  L +    R
Sbjct: 436 FGAGTY-VGLTCKGIDRKGEERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRR 494

Query: 577 VGVLLNCDHGFVIFFAVA-DKVHLMYKFRVDFTEALYPAFWV 617
           +GV ++   G + F+ V  D + L++KF   F+E +Y AFW+
Sbjct: 495 LGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEPVYAAFWL 536


>gi|148833499 midline 1 [Homo sapiens]
          Length = 667

 Score =  152 bits (384), Expect = 9e-37
 Identities = 164/668 (24%), Positives = 276/668 (41%), Gaps = 71/668 (10%)

Query: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNE--------TWAVQG-SPYLCPQCRAVY 57
           L  EL+C ICLE F++P+  PC H+ C +C +           +V+  + + CP CR V 
Sbjct: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63

Query: 58  QARPQ----LHKNTVLCNVVEQFLQADLA-REPPADVWTPPA-RASAPSPNAQVACDHCL 111
               +    L +N  L N++++F +A ++    P++     A  A+  +   +V C  C 
Sbjct: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123

Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQHNRLR- 164
           ++    AVKTC+ C  S+C E L+  H +   F  H L  P+ D   R   C +H   + 
Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183

Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222
             +C    + IC +C +   H+    A+LS+    L+  L   LT +  +       L  
Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243

Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEE----KRVNSKFDTIY 278
           +    Q V + A+R+  +L +E   +  ++         KIKE +    +++  +     
Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303

Query: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKL 333
           Q + +  S    L  + E SL + D   FL+ A  +        ++  V IPE+ LN   
Sbjct: 304 QCIERSAS----LISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDT- 358

Query: 334 IKGIHQSTIDLKNELK--QCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391
                   +D   E K  +C+  L  P P +      +  +    T  V   S +E    
Sbjct: 359 ---FDTFALDFSREKKLLECLDYLTAPNPPT---IREELCTASYDTITVHWTSDDEFS-- 410

Query: 392 KPPPVPALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-- 447
               V +   +   F     +V L  +            +H     L++     F+ K  
Sbjct: 411 ----VVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAI 466

Query: 448 -------SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCS 499
                  S P  L+   +   LD  +AH K+ +S         E        P+RFT   
Sbjct: 467 NQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQG 526

Query: 500 Q--VLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTK 557
              V G      G HYWEV +  + +  +G+ Y S  +      +G+NSASW +   N  
Sbjct: 527 SYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPK---HEWIGKNSASWALCRCNNN 583

Query: 558 ISAWHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616
               HN+ E  + P+    RVG+LL+ D+G + F+   + +HL Y F V F + + P F 
Sbjct: 584 WVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHL-YTFDVAFAQPVCPTFT 642

Query: 617 VFSAGATL 624
           V++   T+
Sbjct: 643 VWNKCLTI 650


>gi|4557753 midline 1 [Homo sapiens]
          Length = 667

 Score =  152 bits (384), Expect = 9e-37
 Identities = 164/668 (24%), Positives = 276/668 (41%), Gaps = 71/668 (10%)

Query: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNE--------TWAVQG-SPYLCPQCRAVY 57
           L  EL+C ICLE F++P+  PC H+ C +C +           +V+  + + CP CR V 
Sbjct: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63

Query: 58  QARPQ----LHKNTVLCNVVEQFLQADLA-REPPADVWTPPA-RASAPSPNAQVACDHCL 111
               +    L +N  L N++++F +A ++    P++     A  A+  +   +V C  C 
Sbjct: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123

Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQHNRLR- 164
           ++    AVKTC+ C  S+C E L+  H +   F  H L  P+ D   R   C +H   + 
Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183

Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222
             +C    + IC +C +   H+    A+LS+    L+  L   LT +  +       L  
Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243

Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEE----KRVNSKFDTIY 278
           +    Q V + A+R+  +L +E   +  ++         KIKE +    +++  +     
Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303

Query: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKL 333
           Q + +  S    L  + E SL + D   FL+ A  +        ++  V IPE+ LN   
Sbjct: 304 QCIERSAS----LISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDT- 358

Query: 334 IKGIHQSTIDLKNELK--QCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391
                   +D   E K  +C+  L  P P +      +  +    T  V   S +E    
Sbjct: 359 ---FDTFALDFSREKKLLECLDYLTAPNPPT---IREELCTASYDTITVHWTSDDEFS-- 410

Query: 392 KPPPVPALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-- 447
               V +   +   F     +V L  +            +H     L++     F+ K  
Sbjct: 411 ----VVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAI 466

Query: 448 -------SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCS 499
                  S P  L+   +   LD  +AH K+ +S         E        P+RFT   
Sbjct: 467 NQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQG 526

Query: 500 Q--VLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTK 557
              V G      G HYWEV +  + +  +G+ Y S  +      +G+NSASW +   N  
Sbjct: 527 SYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPK---HEWIGKNSASWALCRCNNN 583

Query: 558 ISAWHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616
               HN+ E  + P+    RVG+LL+ D+G + F+   + +HL Y F V F + + P F 
Sbjct: 584 WVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHL-YTFDVAFAQPVCPTFT 642

Query: 617 VFSAGATL 624
           V++   T+
Sbjct: 643 VWNKCLTI 650


>gi|15451852 midline 1 [Homo sapiens]
          Length = 667

 Score =  152 bits (384), Expect = 9e-37
 Identities = 164/668 (24%), Positives = 276/668 (41%), Gaps = 71/668 (10%)

Query: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNE--------TWAVQG-SPYLCPQCRAVY 57
           L  EL+C ICLE F++P+  PC H+ C +C +           +V+  + + CP CR V 
Sbjct: 4   LESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATNESVESITAFQCPTCRHVI 63

Query: 58  QARPQ----LHKNTVLCNVVEQFLQADLA-REPPADVWTPPA-RASAPSPNAQVACDHCL 111
               +    L +N  L N++++F +A ++    P++     A  A+  +   +V C  C 
Sbjct: 64  TLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCD 123

Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQHNRLR- 164
           ++    AVKTC+ C  S+C E L+  H +   F  H L  P+ D   R   C +H   + 
Sbjct: 124 QDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKV 183

Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222
             +C    + IC +C +   H+    A+LS+    L+  L   LT +  +       L  
Sbjct: 184 NMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAK 243

Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEE----KRVNSKFDTIY 278
           +    Q V + A+R+  +L +E   +  ++         KIKE +    +++  +     
Sbjct: 244 LIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCK 303

Query: 279 QILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKL 333
           Q + +  S    L  + E SL + D   FL+ A  +        ++  V IPE+ LN   
Sbjct: 304 QCIERSAS----LISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDT- 358

Query: 334 IKGIHQSTIDLKNELK--QCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSK 391
                   +D   E K  +C+  L  P P +      +  +    T  V   S +E    
Sbjct: 359 ---FDTFALDFSREKKLLECLDYLTAPNPPT---IREELCTASYDTITVHWTSDDEFS-- 410

Query: 392 KPPPVPALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-- 447
               V +   +   F     +V L  +            +H     L++     F+ K  
Sbjct: 411 ----VVSYELQYTIFTGQANVVSLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAI 466

Query: 448 -------SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCS 499
                  S P  L+   +   LD  +AH K+ +S         E        P+RFT   
Sbjct: 467 NQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQG 526

Query: 500 Q--VLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTK 557
              V G      G HYWEV +  + +  +G+ Y S  +      +G+NSASW +   N  
Sbjct: 527 SYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPK---HEWIGKNSASWALCRCNNN 583

Query: 558 ISAWHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616
               HN+ E  + P+    RVG+LL+ D+G + F+   + +HL Y F V F + + P F 
Sbjct: 584 WVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHL-YTFDVAFAQPVCPTFT 642

Query: 617 VFSAGATL 624
           V++   T+
Sbjct: 643 VWNKCLTI 650


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score =  144 bits (362), Expect = 3e-34
 Identities = 155/659 (23%), Positives = 255/659 (38%), Gaps = 63/659 (9%)

Query: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS---------PYLCPQCRAV- 56
           L  EL+C ICLE F++P+  PC H+ C SC +       S          + CP CR V 
Sbjct: 24  LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83

Query: 57  ---YQARPQLHKNTVLCNVVEQFLQADLA--REPPADVWTPPARASAPSPNAQVACDHCL 111
              ++    L +N  L N++++F +A ++    P         R +    + ++AC  C 
Sbjct: 84  SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143

Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQH-NRLR 164
           ++    AVKTC+ C  S+C   L+  H +   F  H L  PV D   R   C  H N   
Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203

Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222
             +C    + IC +C +   H+    ASL+     L+ TL   LT +  + +     +  
Sbjct: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263

Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILL 282
           +    Q V +       +L +E  E+  ++   +     KIKE +     K         
Sbjct: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323

Query: 283 KKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKLIKGI 337
           +       L  + E  L + D+  FL+ A  +        ++  V IP++  N       
Sbjct: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN----DAF 379

Query: 338 HQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVP 397
               +D   E K   G      P+     E    ++H  T  V  +S +E        + 
Sbjct: 380 ENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASH-DTITVHWISDDEFS------IS 432

Query: 398 ALPSKLPTFGAPEQLVDLKQA--GLEAAAKATSSHPNSTSLKAKVLETFLAK-------- 447
           +   +   F      + L  +            +H     L++     F+ K        
Sbjct: 433 SYELQYTIFTGQANFISLYNSVDSWMIVPNIKQNHYTVHGLQSGTRYIFIVKAINQAGSR 492

Query: 448 -SRPELLEYYIKVI-LDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRF--TYCSQVLG 503
            S P  L+   +   LD    H K+ +S         E        P+RF  T C    G
Sbjct: 493 NSEPTRLKTNSQPFKLDPKMTHKKLKISNDGLQMEKDESSLKKSHTPERFSGTGCYGAAG 552

Query: 504 LHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHN 563
                 G HYWEV +  + +  +GI Y S  +      +G+N++SW     N+     HN
Sbjct: 553 NIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPK---NEWIGKNASSWVFSRCNSNFVVRHN 609

Query: 564 NVEKTL---PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619
           N E  +   P  K  R+GVLL+ D+  + F+  A+ +HL + F V F   + P F +++
Sbjct: 610 NKEMLVDVPPHLK--RLGVLLDYDNNMLSFYDPANSLHL-HTFDVTFILPVCPTFTIWN 665


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score =  140 bits (354), Expect = 3e-33
 Identities = 161/689 (23%), Positives = 261/689 (37%), Gaps = 93/689 (13%)

Query: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS---------PYLCPQCRAV- 56
           L  EL+C ICLE F++P+  PC H+ C SC +       S          + CP CR V 
Sbjct: 24  LESELTCPICLELFEDPLLLPCAHSLCFSCAHRILVSSCSSGESIEPITAFQCPTCRYVI 83

Query: 57  ---YQARPQLHKNTVLCNVVEQFLQADLA--REPPADVWTPPARASAPSPNAQVACDHCL 111
              ++    L +N  L N++++F +A ++    P         R +    + ++AC  C 
Sbjct: 84  SLNHRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSESRRERTYRPTTAMSSERIACQFCE 143

Query: 112 KEA---AVKTCLVCMASFCQEHLQ-PHFDSPAFQDHPLQPPVRDLLRR--KCSQH-NRLR 164
           ++    AVKTC+ C  S+C   L+  H +   F  H L  PV D   R   C  H N   
Sbjct: 144 QDPPRDAVKTCITCEVSYCDRCLRATHPNKKPFTSHRLVEPVPDTHLRGITCLDHENEKV 203

Query: 165 EFFCPEHSECICHICLV--EHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDD 222
             +C    + IC +C +   H+    ASL+     L+ TL   LT +  + +     +  
Sbjct: 204 NMYCVSDDQLICALCKLVGRHRDHQVASLNDRFEKLKQTLEMNLTNLVKRNSELENQMAK 263

Query: 223 VRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILL 282
           +    Q V +       +L +E  E+  ++   +     KIKE +     K         
Sbjct: 264 LIQICQQVEVNTAMHEAKLMEECDELVEIIQQRKQMIAVKIKETKVMKLRKLAQQVANCR 323

Query: 283 KKKSEIQTLKEEIEQSLTKRDEFEFLEKASKL-----RGISTKPVYIPEVELNHKLIKGI 337
           +       L  + E  L + D+  FL+ A  +        ++  V IP++  N       
Sbjct: 324 QCLERSTVLINQAEHILKENDQARFLQSAKNIAERVAMATASSQVLIPDINFN----DAF 379

Query: 338 HQSTIDLKNELK--QCIGRLQEPTPSSGD----PGEHDPASTHKSTRPVKKVSKEE---- 387
               +D   E K  + +  L  P P S         HD  + H  +     +S  E    
Sbjct: 380 ENFALDFSREKKLLEGLDYLTAPNPPSIREELCTASHDTITVHWISDDEFSISSYELQYT 439

Query: 388 ----------------------KKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAK 425
                                 +K K+      L       GAP  L +   + +     
Sbjct: 440 IFTGQANFISKSWCSWGLWPEIRKCKEAVSCSRLA------GAPRGLYNSVDSWM-IVPN 492

Query: 426 ATSSHPNSTSLKAKVLETFLAK---------SRPELLEYYIKVI-LDYNTAHNKVALSEC 475
              +H     L++     F+ K         S P  L+   +   LD    H K+ +S  
Sbjct: 493 IKQNHYTVHGLQSGTRYIFIVKAINQAGSRNSEPTRLKTNSQPFKLDPKMTHKKLKISND 552

Query: 476 YTVASVAEMPQNYRPHPQRF--TYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSM 533
                  E        P+RF  T C    G      G HYWEV +  + +  +GI Y S 
Sbjct: 553 GLQMEKDESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSA 612

Query: 534 NRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTL---PSTKATRVGVLLNCDHGFVIF 590
            +      +G+N++SW     N+     HNN E  +   P  K  R+GVLL+ D+  + F
Sbjct: 613 PK---NEWIGKNASSWVFSRCNSNFVVRHNNKEMLVDVPPHLK--RLGVLLDYDNNMLSF 667

Query: 591 FAVADKVHLMYKFRVDFTEALYPAFWVFS 619
           +  A+ +HL + F V F   + P F +++
Sbjct: 668 YDPANSLHL-HTFDVTFILPVCPTFTIWN 695


>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
          Length = 517

 Score =  132 bits (331), Expect = 1e-30
 Identities = 143/627 (22%), Positives = 231/627 (36%), Gaps = 138/627 (22%)

Query: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKN 66
           L E+L+C+ICL  +++PVT PCGHNFCG+C+ + W   G    CP+CR  +    +L +N
Sbjct: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKA--CPECREPFPDGAELRRN 63

Query: 67  TVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASF 126
             L  V+E  ++A  AR+P       P     P P A                       
Sbjct: 64  VALSGVLE-VVRAGPARDPG------PDPGPGPDPAA----------------------- 93

Query: 127 CQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV-EHKT 185
                                        +C +H R  E FC     C+C +C V E + 
Sbjct: 94  -----------------------------RCPRHGRPLELFCRTEGRCVCSVCTVRECRL 124

Query: 186 CSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEY 245
              A L       EA LR  L V   Q   A   L ++R +   ++ +A      +  ++
Sbjct: 125 HERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKF 184

Query: 246 TEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEF 305
           + +   L+   TT+ R I+  +           Q L + + E Q L+  +E         
Sbjct: 185 SSLLQALEIQHTTALRSIEVAKT----------QALAQARDEEQRLRVHLEA-------- 226

Query: 306 EFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDP 365
                  ++R                +L++ + + T   +++L Q  G L   TP   D 
Sbjct: 227 -VARHGCRIR----------------ELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDE 269

Query: 366 GEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAK 425
            +         +R    + +E       P  PA P  L    AP  L  +          
Sbjct: 270 DQQLGDLKQLLSRLCGLLLEEGSH----PGAPAKPVDLAPVEAPGPLAPVPST------- 318

Query: 426 ATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMP 485
                              +   R +L + Y  +  D  +A+    LS       V    
Sbjct: 319 -------------------VCPLRRKLWQNYRNLTFDPVSANRHFYLSR--QDQQVKHCR 357

Query: 486 QNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNR--QGPES-RL 542
           Q+  P         QV     ++ G HYWEV    ++   +G+ Y  + R   GP +  +
Sbjct: 358 QSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVT-LGVSYPQLPRCRLGPHTDNI 416

Query: 543 GRNSASW--CVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM 600
           GR   SW  CV+     + AWHN   + LP      +G+ L+   G + F+++  +   +
Sbjct: 417 GRGPCSWGLCVQ--EDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPL 474

Query: 601 YKFRVDFTEALYPAFWVFSAGATLSIC 627
           Y F   F + L P FW+   G TL++C
Sbjct: 475 YTFHALFNQPLTPVFWLLE-GRTLTLC 500


>gi|148596968 tripartite motif-containing 8 [Homo sapiens]
          Length = 551

 Score =  126 bits (317), Expect = 5e-29
 Identities = 85/314 (27%), Positives = 129/314 (41%), Gaps = 25/314 (7%)

Query: 9   EELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTV 68
           EEL C ICL  F EPV  PC HNFC  C+ E WA       CP+C   Y  +P L KN  
Sbjct: 11  EELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLK 70

Query: 69  LCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQ 128
           L N+VE+F  A    +PPA +     R   P P             A K CL C A  CQ
Sbjct: 71  LTNIVEKF-NALHVEKPPAALHCVFCRRGPPLP-------------AQKVCLRCEAPCCQ 116

Query: 129 EHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSP 188
            H+Q H   P+     L     D+    C QHN  R + C      +C  C       S 
Sbjct: 117 SHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCY----YSG 172

Query: 189 ASLSQASADLEA---TLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQE- 244
           A    +  D+E     +R  L     ++    + ++D   + +  +     KV QL++E 
Sbjct: 173 AHQGHSVCDVEIRRNEIRKMLMKQQDRLEEREQDIEDQLYKLESDKRLVEEKVNQLKEEV 232

Query: 245 ---YTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTK 301
              Y ++  LLD     +   + + + +  S+       L ++  E + L   ++    K
Sbjct: 233 RLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDK 292

Query: 302 RDEFEFLEKASKLR 315
            ++  F++    ++
Sbjct: 293 TEDVSFMKNTKSVK 306


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  125 bits (315), Expect = 9e-29
 Identities = 142/619 (22%), Positives = 230/619 (37%), Gaps = 144/619 (23%)

Query: 2   AELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARP 61
           A L  L  E SCS+CLE  KEPV   CGHNFC +C+   W                    
Sbjct: 18  AALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWE------------------- 58

Query: 62  QLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLV 121
                             DL R+ P  V    +R  +  PN Q+              +V
Sbjct: 59  ------------------DLERDFPCPVCRKTSRYRSLRPNRQLGS------------MV 88

Query: 122 CMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV 181
            +A   Q                ++  +RD     C QH+     FC E  E +C IC +
Sbjct: 89  EIAKQLQA---------------VKRKIRD--ESLCPQHHEALSLFCYEDQEAVCLICAI 131

Query: 182 E--HKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVE 239
              H+  +   L  A+ + +  L+  L  +  ++   +R       +  +++     + +
Sbjct: 132 SHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQ 191

Query: 240 QLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSL 299
           Q+ +E+ E+   LD  +     +++EEE+ +                 +Q L+E      
Sbjct: 192 QILREFEELHRRLDEEQQVLLSRLEEEEQDI-----------------LQRLRENAAHLG 234

Query: 300 TKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPT 359
            KR +   L                   E+  K ++   +   D+K+ L++ I R    +
Sbjct: 235 DKRRDLAHL-----------------AAEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGS 277

Query: 360 PSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAG 419
            S+  P +H           VK++++ E              K+ T       ++L+   
Sbjct: 278 LSTICPRDHKAL-----LGLVKEINRCE--------------KVKTMEVTSVSIELE--- 315

Query: 420 LEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVA 479
                K  S+ P       K+L+  +A            V LD  TAH  + LSE     
Sbjct: 316 -----KNFSNFPRQYFALRKILKQLIA-----------DVTLDPETAHPNLVLSEDRKSV 359

Query: 480 SVAEMPQNYRPH-PQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGP 538
              E      P  P+RFT+   VL    +  G HYWEVE+       VG+C  S++R+G 
Sbjct: 360 KFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGE 419

Query: 539 ESRLGRNSASWCVE-WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKV 597
            + L   +  W V  W   K +A            K  RVG+ L+ + G + F+ V D+ 
Sbjct: 420 LTPL-PETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRS 478

Query: 598 HLMYKFRVDFTEALYPAFW 616
           H+ Y F   FTE L+P F+
Sbjct: 479 HI-YTFTDTFTEKLWPLFY 496


>gi|17402909 tripartite motif protein TRIM29 [Homo sapiens]
          Length = 588

 Score =  115 bits (288), Expect = 1e-25
 Identities = 76/257 (29%), Positives = 128/257 (49%), Gaps = 14/257 (5%)

Query: 100 SPNAQVACDHCL--KEAAVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKC 157
           S + +V CD C+  K+ AVK+CLVC ASFC+ HL+PH +  AF+DH L  P+RD   RKC
Sbjct: 166 SGSEEVLCDSCIGNKQKAVKSCLVCQASFCELHLKPHLEGAAFRDHQLLEPIRDFEARKC 225

Query: 158 SQHNRLREFFCPEHSECICHICLV-EHKTCSPASLSQASADLEATL---RHKLTVMYSQI 213
             H +  E FC     CIC++C+  EHK  S  ++ +A A+ E  L   + +L +   +I
Sbjct: 226 PVHGKTMELFCQTDQTCICYLCMFQEHKNHSTVTVEEAKAEKETELSLQKEQLQLKIIEI 285

Query: 214 NGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSK 273
              +      ++R +    T N K   L+Q + ++   L+  +      +++ E+    +
Sbjct: 286 EDEAEKWQKEKDRIKS--FTTNEKA-ILEQNFRDLVRDLEKQKEEVRAALEQREQDAVDQ 342

Query: 274 FDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKL 333
              I   L ++   +   K+  EQ  +  D   FL++   L    + P   P +   H L
Sbjct: 343 VKVIMDALDERAKVLHEDKQTREQLHSISDSVLFLQEFGALMSNYSLP---PPLPTYHVL 399

Query: 334 I--KGIHQSTIDLKNEL 348
           +  +G+ QS  + K++L
Sbjct: 400 LEGEGLGQSLGNFKDDL 416


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  103 bits (257), Expect = 5e-22
 Identities = 118/485 (24%), Positives = 204/485 (42%), Gaps = 85/485 (17%)

Query: 156 KCSQH-NRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQIN 214
           +C +H +R+ E FC     C+C +C V                                 
Sbjct: 23  RCPEHGDRVAELFCRRCRRCVCALCPV--------------------------------- 49

Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274
                L   R     + + A   V++L QE  +  A+       +  +I++  +++ +  
Sbjct: 50  -----LGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANA 104

Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334
           ++    L  K +E++ L +E E++L K+    F++K ++L    T  VY  + +   +  
Sbjct: 105 ESSKTWLKGKFTELRLLLDE-EEALAKK----FIDKNTQL----TLQVYREQADSCRE-- 153

Query: 335 KGIHQSTIDLKNELKQCIGRL-QEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKP 393
                  +D+ N+L   +  + QEP     DP +   A T       +++S  E     P
Sbjct: 154 ------QLDIMNDLSNRVWSISQEP-----DPVQRLQAYTATEQEMQQQMSLGELCH--P 200

Query: 394 PPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATS----SHPNSTSLKAKVLETFLAKSR 449
            P+   P K    G  E +    Q  L+   K +     S P+ST     +L+T  +  R
Sbjct: 201 VPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTK-PGTLLKTSPSPER 259

Query: 450 PELLEYYIKVILDYNTAHNKVALS------ECYTVASVAEMPQNYRPHPQRFTYCSQVLG 503
             LL+Y     LD +T H ++ LS       C  + S+  +P        RF    QVL 
Sbjct: 260 SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPV------LRFDALWQVLA 313

Query: 504 LHCYKKGIHYWEVELQKNNF-CGVGICYGSMNRQGPES--RLGRNSASWCVEWFNTKISA 560
             C+  G HYWEV++Q+      VG  Y S+ R+G  +  RLG N  SWC++ ++ +  A
Sbjct: 314 RDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWA 373

Query: 561 WHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619
           +H+     L P     R+GV L+ + G + F+ V   +  ++ FR  F E LYPA  ++ 
Sbjct: 374 FHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWE 433

Query: 620 AGATL 624
              ++
Sbjct: 434 GAISI 438


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  103 bits (257), Expect = 5e-22
 Identities = 118/485 (24%), Positives = 204/485 (42%), Gaps = 85/485 (17%)

Query: 156 KCSQH-NRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQIN 214
           +C +H +R+ E FC     C+C +C V                                 
Sbjct: 23  RCPEHGDRVAELFCRRCRRCVCALCPV--------------------------------- 49

Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274
                L   R     + + A   V++L QE  +  A+       +  +I++  +++ +  
Sbjct: 50  -----LGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANA 104

Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334
           ++    L  K +E++ L +E E++L K+    F++K ++L    T  VY  + +   +  
Sbjct: 105 ESSKTWLKGKFTELRLLLDE-EEALAKK----FIDKNTQL----TLQVYREQADSCRE-- 153

Query: 335 KGIHQSTIDLKNELKQCIGRL-QEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKP 393
                  +D+ N+L   +  + QEP     DP +   A T       +++S  E     P
Sbjct: 154 ------QLDIMNDLSNRVWSISQEP-----DPVQRLQAYTATEQEMQQQMSLGELCH--P 200

Query: 394 PPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATS----SHPNSTSLKAKVLETFLAKSR 449
            P+   P K    G  E +    Q  L+   K +     S P+ST     +L+T  +  R
Sbjct: 201 VPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTK-PGTLLKTSPSPER 259

Query: 450 PELLEYYIKVILDYNTAHNKVALS------ECYTVASVAEMPQNYRPHPQRFTYCSQVLG 503
             LL+Y     LD +T H ++ LS       C  + S+  +P        RF    QVL 
Sbjct: 260 SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPV------LRFDALWQVLA 313

Query: 504 LHCYKKGIHYWEVELQKNNF-CGVGICYGSMNRQGPES--RLGRNSASWCVEWFNTKISA 560
             C+  G HYWEV++Q+      VG  Y S+ R+G  +  RLG N  SWC++ ++ +  A
Sbjct: 314 RDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWA 373

Query: 561 WHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619
           +H+     L P     R+GV L+ + G + F+ V   +  ++ FR  F E LYPA  ++ 
Sbjct: 374 FHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWE 433

Query: 620 AGATL 624
              ++
Sbjct: 434 GAISI 438


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  103 bits (257), Expect = 5e-22
 Identities = 118/485 (24%), Positives = 204/485 (42%), Gaps = 85/485 (17%)

Query: 156 KCSQH-NRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQIN 214
           +C +H +R+ E FC     C+C +C V                                 
Sbjct: 23  RCPEHGDRVAELFCRRCRRCVCALCPV--------------------------------- 49

Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274
                L   R     + + A   V++L QE  +  A+       +  +I++  +++ +  
Sbjct: 50  -----LGAHRGHPVGLALEAAVHVQKLSQECLKQLAIKKQQHIDNITQIEDATEKLKANA 104

Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334
           ++    L  K +E++ L +E E++L K+    F++K ++L    T  VY  + +   +  
Sbjct: 105 ESSKTWLKGKFTELRLLLDE-EEALAKK----FIDKNTQL----TLQVYREQADSCRE-- 153

Query: 335 KGIHQSTIDLKNELKQCIGRL-QEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKP 393
                  +D+ N+L   +  + QEP     DP +   A T       +++S  E     P
Sbjct: 154 ------QLDIMNDLSNRVWSISQEP-----DPVQRLQAYTATEQEMQQQMSLGELCH--P 200

Query: 394 PPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATS----SHPNSTSLKAKVLETFLAKSR 449
            P+   P K    G  E +    Q  L+   K +     S P+ST     +L+T  +  R
Sbjct: 201 VPLSFEPVKSFFKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTK-PGTLLKTSPSPER 259

Query: 450 PELLEYYIKVILDYNTAHNKVALS------ECYTVASVAEMPQNYRPHPQRFTYCSQVLG 503
             LL+Y     LD +T H ++ LS       C  + S+  +P        RF    QVL 
Sbjct: 260 SLLLKYARTPTLDPDTMHARLRLSADRLTVRCGLLGSLGPVPV------LRFDALWQVLA 313

Query: 504 LHCYKKGIHYWEVELQKNNF-CGVGICYGSMNRQGPES--RLGRNSASWCVEWFNTKISA 560
             C+  G HYWEV++Q+      VG  Y S+ R+G  +  RLG N  SWC++ ++ +  A
Sbjct: 314 RDCFATGRHYWEVDVQEAGAGWWVGAAYASLRRRGASAAARLGCNRQSWCLKRYDLEYWA 373

Query: 561 WHNNVEKTL-PSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFS 619
           +H+     L P     R+GV L+ + G + F+ V   +  ++ FR  F E LYPA  ++ 
Sbjct: 374 FHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRLWE 433

Query: 620 AGATL 624
              ++
Sbjct: 434 GAISI 438


>gi|37655167 ring finger protein 135 isoform 1 [Homo sapiens]
          Length = 432

 Score = 90.5 bits (223), Expect = 4e-18
 Identities = 52/140 (37%), Positives = 78/140 (55%), Gaps = 5/140 (3%)

Query: 480 SVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPE 539
           +V+  PQ YR   +RF+  SQVL       G HYWEV+ +  +   VG+    M+R   +
Sbjct: 282 TVSHRPQPYRWSCERFS-TSQVLCSQALSSGKHYWEVDTRNCSHWAVGVASWEMSR---D 337

Query: 540 SRLGRNSASWCVEWFNT-KISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVH 598
             LGR   S CVEW  T ++SAWH   E  L S +   VG+ LN + G + F++V ++  
Sbjct: 338 QVLGRTMDSCCVEWKGTSQLSAWHMVKETVLGSDRPGVVGIWLNLEEGKLAFYSVDNQEK 397

Query: 599 LMYKFRVDFTEALYPAFWVF 618
           L+Y+  +  +  LYPAFW++
Sbjct: 398 LLYECTISASSPLYPAFWLY 417



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 5/96 (5%)

Query: 9   EELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS-PYLCPQCRAVYQARPQLHKNT 67
           ++L C IC      P T PCGH+FC  CL   W  + +  + CP CR     +P L KNT
Sbjct: 17  DDLGCIICQGLLDWPATLPCGHSFCRHCLEALWGARDARRWACPTCRQGAAQQPHLRKNT 76

Query: 68  VLCNVVEQFLQADLAREPPADVWTPPARASAPSPNA 103
           +L ++ +++ +A  ARE  A   + PA    P  ++
Sbjct: 77  LLQDLADKYRRA--AREIQAG--SDPAHCPCPGSSS 108


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score = 85.9 bits (211), Expect = 1e-16
 Identities = 68/227 (29%), Positives = 103/227 (45%), Gaps = 19/227 (8%)

Query: 417 QAGLEAAAKATSSHPNSTSLKAKVLETF-LAKSRPELLEYY-----------IKVILDYN 464
           Q+ LE   +A S H    +LK   L +F L K    L   Y           + VILD N
Sbjct: 243 QSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGFSLPPQYSGLDRIIKPFQVDVILDLN 302

Query: 465 TAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFC 524
           TAH ++ +SE           +N    P+RF  C  VLG   +  G HYWEVE+      
Sbjct: 303 TAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWEVEVGNKPKW 362

Query: 525 GVGICYGSM--NRQGPESRLGRNSASWCV-EWFNTKISAWHNNVEKTLPSTKATRVGVLL 581
            +G+C   +  N Q   S LG     W +  +  +   A      + LP  K +++G+ L
Sbjct: 363 ILGVCQDCLLRNWQDQPSVLG---GFWAIGRYMKSGYVASGPKTTQLLPVVKPSKIGIFL 419

Query: 582 NCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSICS 628
           + + G + F+ + D+  ++Y F   FTEA++P F+  +    L ICS
Sbjct: 420 DYELGDLSFYNMNDR-SILYTFNDCFTEAVWPYFYTGTDSEPLKICS 465



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 70/311 (22%), Positives = 120/311 (38%), Gaps = 62/311 (19%)

Query: 4   LCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQL 63
           L  L EE SC ICLE  K+PVT  CGHNFC SCL+ +W      + CP CR  +  +   
Sbjct: 7   LVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKDLDDTFPCPVCRFCFPYK-SF 65

Query: 64  HKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCM 123
            +N  L N+ E   Q  + R          ++      NA      C K     T     
Sbjct: 66  RRNPQLRNLTEIAKQLQIRR----------SKRKRQKENAM-----CEKHNQFLTL---- 106

Query: 124 ASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEH 183
             FC + L                   ++L  +CS        F  +H          +H
Sbjct: 107 --FCVKDL-------------------EILCTQCS--------FSTKHQ---------KH 128

Query: 184 KTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQ 243
             C    + +A++     L   L  + + I    + +    ++  +++     K E++  
Sbjct: 129 YIC---PIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKKKVEYKREEINS 185

Query: 244 EYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRD 303
           E+ +++  L   +    R+I++EE  + +K +     L    S ++ L  E+E   + + 
Sbjct: 186 EFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLLREVE-GKSVQS 244

Query: 304 EFEFLEKASKL 314
             E L +A  +
Sbjct: 245 NLELLTQAKSM 255


>gi|89886468 fibronectin type III and SPRY domain containing 1-like
           isoform 1 [Homo sapiens]
          Length = 498

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 53/151 (35%), Positives = 75/151 (49%), Gaps = 9/151 (5%)

Query: 480 SVAEMPQNYRPHPQRFTYCSQ-VLGLHCYKKGIHYWEVELQKN-NFCGVGICYGSMNRQG 537
           SV   P   R    RFT  S  VLG    + G HYWEV+ QK+     VG+ Y ++   G
Sbjct: 320 SVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTL---G 376

Query: 538 PESRLGRNSASWCVE---WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVA 594
              +LG+ + SWC+    W     +A HNN  K L  T   ++GV  + D G + F+   
Sbjct: 377 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDAN 436

Query: 595 DKVHLMYKFRVDFTEALYPAFWVFSAGATLS 625
            K  L+Y F+  FT+ + P F V+  G +LS
Sbjct: 437 SK-QLLYSFKTKFTQPVLPGFMVWCGGLSLS 466


>gi|223718222 fibronectin type III and SPRY domain containing 1-like
           isoform 3 [Homo sapiens]
          Length = 530

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 53/151 (35%), Positives = 75/151 (49%), Gaps = 9/151 (5%)

Query: 480 SVAEMPQNYRPHPQRFTYCSQ-VLGLHCYKKGIHYWEVELQKN-NFCGVGICYGSMNRQG 537
           SV   P   R    RFT  S  VLG    + G HYWEV+ QK+     VG+ Y ++   G
Sbjct: 352 SVGSRPPAVRGSRDRFTGESYTVLGDTAIESGQHYWEVKAQKDCKSYSVGVAYKTL---G 408

Query: 538 PESRLGRNSASWCVE---WFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVA 594
              +LG+ + SWC+    W     +A HNN  K L  T   ++GV  + D G + F+   
Sbjct: 409 KFDQLGKTNTSWCIHVNNWLQNTFAAKHNNKVKALDVTVPEKIGVFCDFDGGQLSFYDAN 468

Query: 595 DKVHLMYKFRVDFTEALYPAFWVFSAGATLS 625
            K  L+Y F+  FT+ + P F V+  G +LS
Sbjct: 469 SK-QLLYSFKTKFTQPVLPGFMVWCGGLSLS 498



 Score = 30.8 bits (68), Expect = 3.9
 Identities = 33/190 (17%), Positives = 80/190 (42%), Gaps = 7/190 (3%)

Query: 180 LVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVE 239
           L+ + T  P S++      +  L+  ++ + ++ +     +D + +  + V+  ++  + 
Sbjct: 22  LISNITIGPESINLQ----QEALQRIISTLANKNDEIQNFIDTLHHTLKGVQENSSNILS 77

Query: 240 QLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSL 299
           +L +E+  + ++LD  + +    IK+E+ R + +  +            + L E   +SL
Sbjct: 78  ELDEEFDSLYSILDEVKESMINCIKQEQARKSQELQSQISQCNNALENSEELLEFATRSL 137

Query: 300 TKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNE--LKQCIGRLQE 357
             ++  EF + A +++   T       + L  K+   +    +D   E  + Q +  L  
Sbjct: 138 DIKEPEEFSKAARQIKDRVTMASAF-RLSLKPKVSDNMTHLMVDFSQERQMLQTLKFLPV 196

Query: 358 PTPSSGDPGE 367
           P     DP E
Sbjct: 197 PKAPEIDPVE 206


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 71/294 (24%), Positives = 127/294 (43%), Gaps = 44/294 (14%)

Query: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKN 66
           + EEL+C ICL+ F++PV+  CGHNFC  CL+  WA  G P+ CP+CR    A   L  N
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHP-SAPAALRPN 64

Query: 67  TVLCNVVEQFLQADLAREPP---ADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCM 123
             L  + E+  +  L   PP      W P           ++ C+    +     CLVC 
Sbjct: 65  WALARLTEKTQRRRLGPVPPGLCGRHWEP----------LRLFCE----DDQRPVCLVCR 110

Query: 124 ASFCQEHLQPHFDSP---AFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICL 180
            S  QEH Q H  +P   AF+                S      +    E    +  + L
Sbjct: 111 ES--QEH-QTHAMAPIDEAFE----------------SYRTGNFDIHVDEWKRRLIRLLL 151

Query: 181 VEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQ 240
              K      L ++  +L A ++  + +   ++  A++  D +++++  +    ++    
Sbjct: 152 YHSK--QEEKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSKLHNF 209

Query: 241 LQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLK--KKSEIQTLK 292
           L +E       L+  E  + +K+ E   ++N    ++ +++L+  +KS+  TL+
Sbjct: 210 LVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLE 263


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 87/372 (23%), Positives = 138/372 (37%), Gaps = 81/372 (21%)

Query: 2   AELCPLAEEL----SCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGS----------- 46
           AE   LA EL    +CSICLE F+EPV+  CGH+FC +C+   W   G+           
Sbjct: 14  AEALALAAELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPP 73

Query: 47  -PYLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQV 105
            P  CPQCR                                      PAR S   PN Q+
Sbjct: 74  FPLPCPQCR-------------------------------------EPARPSQLRPNRQL 96

Query: 106 ACDHCLKEAAVKTCLVCMASFCQEHLQPHFDSPAFQ--DHPLQPPVRDLLRRKCSQHNRL 163
                   AAV T L              F  PA    +H  Q         +C QH   
Sbjct: 97  --------AAVATLL------------RRFSLPAAAPGEHGSQAAAARAAAARCGQHGEP 136

Query: 164 REFFCPEHSECICHIC--LVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALD 221
            + +C +    IC +C    EH+  +   L +A  + +  L  +L V+  ++        
Sbjct: 137 FKLYCQDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRS 196

Query: 222 DVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQIL 281
             +   +++      + E++  E+  ++A L   E     +++E  + V  K +     L
Sbjct: 197 TEKKESKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQL 256

Query: 282 LKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEV---ELNHKLIKGIH 338
             + +++  L  +I+++  K D     E  S L   S  P   P     E+ +K +  + 
Sbjct: 257 GVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNK-VWNVS 315

Query: 339 QSTIDLKNELKQ 350
             T  LK  LK+
Sbjct: 316 LKTFVLKGMLKK 327



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%)

Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411
           +GRL+E +         + A        + K+S + +++ + P +  L     T      
Sbjct: 235 LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 294

Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466
           +   K   + +  K   +   + SLK  VL+  L K + +L      E  +++ LD +TA
Sbjct: 295 VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 351

Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526
           + ++ LS       + E  Q+   HP RF   ++VL    +  G H+WEVE+   +    
Sbjct: 352 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 411

Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586
           G+   S+ R+G  +        W ++    +  A  +     L     +RV V L+ + G
Sbjct: 412 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 470

Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626
            V F+AV D  HL Y FRV+F E ++P F V S G  L I
Sbjct: 471 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 509


>gi|239751227 PREDICTED: hypothetical protein XP_002347761 [Homo
           sapiens]
          Length = 282

 Score = 80.5 bits (197), Expect = 4e-15
 Identities = 41/102 (40%), Positives = 53/102 (51%), Gaps = 4/102 (3%)

Query: 104 QVACDHCLKEA----AVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQ 159
           +V CD CL +     AVK+CL CM ++C+EHLQPH  +   Q H L  PV+D   R C  
Sbjct: 74  EVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPA 133

Query: 160 HNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEAT 201
           H+     FC    +CIC  C  EH   +  SL  A  D E +
Sbjct: 134 HHSPLSAFCCPDQQCICQDCCQEHSGHTIVSLDAARRDKEVS 175


>gi|27734883 tripartite motif family-like 2 [Homo sapiens]
          Length = 387

 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 89/403 (22%), Positives = 158/403 (39%), Gaps = 50/403 (12%)

Query: 215 GASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKF 274
           G   A ++ R   Q++  T+  K+E  +   T+        E      I+EEE+      
Sbjct: 4   GIQEAAENYRKLFQEILNTSREKLEAAKSILTD--------EQERMAMIQEEEQNFKKMI 55

Query: 275 DTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLI 334
           ++ Y + L+       L EE EQ+L ++ E                   I ++ L   L+
Sbjct: 56  ESEYSMRLR------LLNEECEQNLQRQQEC------------------ISDLNLRETLL 91

Query: 335 KGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPP 394
               +   +L+   ++ + RL      + +  +   A   +  R + K+  E +K     
Sbjct: 92  NQAIKLATELEEMFQEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGEG 151

Query: 395 PVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLE 454
            +  L +   +    + L+ L+          +  H    S   +VL+  L         
Sbjct: 152 TLALLKNAKYSLERSKSLL-LEHLEPAHITDLSLCHIRGLSSMFRVLQRHLT-------- 202

Query: 455 YYIKVILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYW 514
                 LD  TAH  +ALSE      +    Q+   +P+R  + + VL    +  G HYW
Sbjct: 203 ------LDPETAHPCLALSEDLRTMRLRHGQQDGAGNPERLDFSAMVLAAESFTSGRHYW 256

Query: 515 EVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAW-HNNVEKTLPSTK 573
           EV+++K     VGI +GS + +G  +R              T+ + W    +++     K
Sbjct: 257 EVDVEKATRWQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKK 316

Query: 574 ATRVGVLLNCDHGFVIFFAVADKVHLMYKF-RVDFTEALYPAF 615
              VGV L+C+HG + F+ V + + L+Y F    F  AL P F
Sbjct: 317 LDTVGVFLDCEHGQISFYNVTE-MSLIYNFSHCAFQGALRPVF 358


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 80/359 (22%), Positives = 134/359 (37%), Gaps = 78/359 (21%)

Query: 2   AELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARP 61
           A L  L  E SCS+CLE  KEPV   CGHNFC +C+   W                    
Sbjct: 18  AALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWE------------------- 58

Query: 62  QLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLV 121
                             DL R+ P  V    +R  +  PN Q+              +V
Sbjct: 59  ------------------DLERDFPCPVCRKTSRYRSLRPNRQLGS------------MV 88

Query: 122 CMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV 181
            +A   Q                ++  +RD     C QH+     FC E  E +C IC +
Sbjct: 89  EIAKQLQA---------------VKRKIRD--ESLCPQHHEALSLFCYEDQEAVCLICAI 131

Query: 182 E--HKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVE 239
              H+  +   L  A+ + +  L+  L  +  ++   +R       +  +++     + +
Sbjct: 132 SHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLVESRRQ 191

Query: 240 QLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSL 299
           Q+ +E+ E+   LD  +     +++EEE+ +  +       L  K+ ++  L  E+E   
Sbjct: 192 QILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAEVEGKC 251

Query: 300 TK------RDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCI 352
            +      +D    LEK  K++ +    V I E+E N        +    L+  LKQ I
Sbjct: 252 LQSGFEMLKDVKSTLEKCEKVKTMEVTSVSI-ELEKN---FSNFPRQYFALRKILKQLI 306



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 65/213 (30%), Positives = 94/213 (44%), Gaps = 9/213 (4%)

Query: 410 EQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKS----RPELLEYYIKVILDYNT 465
           E L D+K   LE   K  +    S S++ +   +   +     R  L +    V LD  T
Sbjct: 257 EMLKDVKST-LEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPET 315

Query: 466 AHNKVALSECYTVASVAEMPQNYRPH-PQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFC 524
           AH  + LSE        E      P  P+RFT+   VL    +  G HYWEVE+      
Sbjct: 316 AHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHW 375

Query: 525 GVGICYGSMNRQGPESRLGRNSASWCVE-WFNTKISAWHNNVEKTLPSTKATRVGVLLNC 583
            VG+C  S++R+G  + L   +  W V  W   K +A            K  RVG+ L+ 
Sbjct: 376 AVGVCRDSVSRKGELTPL-PETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDY 434

Query: 584 DHGFVIFFAVADKVHLMYKFRVDFTEALYPAFW 616
           + G + F+ V D+ H+ Y F   FTE L+P F+
Sbjct: 435 EAGTLSFYNVTDRSHI-YTFTDTFTEKLWPLFY 466


>gi|44680130 tripartite motif-containing 7 isoform 2 [Homo sapiens]
          Length = 329

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%)

Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411
           +GRL+E +         + A        + K+S + +++ + P +  L     T      
Sbjct: 53  LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 112

Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466
           +   K   + +  K   +   + SLK  VL+  L K + +L      E  +++ LD +TA
Sbjct: 113 VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 169

Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526
           + ++ LS       + E  Q+   HP RF   ++VL    +  G H+WEVE+   +    
Sbjct: 170 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 229

Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586
           G+   S+ R+G  +        W ++    +  A  +     L     +RV V L+ + G
Sbjct: 230 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 288

Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626
            V F+AV D  HL Y FRV+F E ++P F V S G  L I
Sbjct: 289 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 327


>gi|44680128 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%)

Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411
           +GRL+E +         + A        + K+S + +++ + P +  L     T      
Sbjct: 27  LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 86

Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466
           +   K   + +  K   +   + SLK  VL+  L K + +L      E  +++ LD +TA
Sbjct: 87  VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 143

Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526
           + ++ LS       + E  Q+   HP RF   ++VL    +  G H+WEVE+   +    
Sbjct: 144 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 203

Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586
           G+   S+ R+G  +        W ++    +  A  +     L     +RV V L+ + G
Sbjct: 204 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 262

Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626
            V F+AV D  HL Y FRV+F E ++P F V S G  L I
Sbjct: 263 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 301


>gi|44680126 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%)

Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411
           +GRL+E +         + A        + K+S + +++ + P +  L     T      
Sbjct: 27  LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 86

Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466
           +   K   + +  K   +   + SLK  VL+  L K + +L      E  +++ LD +TA
Sbjct: 87  VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 143

Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526
           + ++ LS       + E  Q+   HP RF   ++VL    +  G H+WEVE+   +    
Sbjct: 144 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 203

Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586
           G+   S+ R+G  +        W ++    +  A  +     L     +RV V L+ + G
Sbjct: 204 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 262

Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626
            V F+AV D  HL Y FRV+F E ++P F V S G  L I
Sbjct: 263 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 301


>gi|44680124 tripartite motif-containing 7 isoform 3 [Homo sapiens]
          Length = 303

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 73/280 (26%), Positives = 123/280 (43%), Gaps = 10/280 (3%)

Query: 352 IGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQ 411
           +GRL+E +         + A        + K+S + +++ + P +  L     T      
Sbjct: 27  LGRLEELSREVAQKQNENLAQLGVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSN 86

Query: 412 LVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELL-----EYYIKVILDYNTA 466
           +   K   + +  K   +   + SLK  VL+  L K + +L      E  +++ LD +TA
Sbjct: 87  VPGPKPTTVSSEMK---NKVWNVSLKTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTA 143

Query: 467 HNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGV 526
           + ++ LS       + E  Q+   HP RF   ++VL    +  G H+WEVE+   +    
Sbjct: 144 NPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAF 203

Query: 527 GICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHG 586
           G+   S+ R+G  +        W ++    +  A  +     L     +RV V L+ + G
Sbjct: 204 GVARESVRRKG-LTPFTPEEGVWALQLNGGQYWAVTSPERSPLSCGHLSRVRVALDLEVG 262

Query: 587 FVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSI 626
            V F+AV D  HL Y FRV+F E ++P F V S G  L I
Sbjct: 263 AVSFYAVEDMRHL-YTFRVNFQERVFPLFSVCSTGTYLRI 301


>gi|31881693 butyrophilin, subfamily 2, member A2 isoform b [Homo
           sapiens]
          Length = 407

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 56/170 (32%), Positives = 86/170 (50%), Gaps = 3/170 (1%)

Query: 459 VILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518
           V+LD +TAH ++ LSE           Q    +P+RF     VLG   +  G HYWEVE+
Sbjct: 213 VVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEV 272

Query: 519 QKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKA-TRV 577
           +      VG+C  S+ R+G E  L   +  W +E F  +  A  ++ E+ LP  ++  RV
Sbjct: 273 ENVMVWTVGVCRHSVERKG-EVLLIPQNGFWTLEMFGNQYRAL-SSPERILPLKESLCRV 330

Query: 578 GVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSIC 627
           GV L+ + G V F+ + D+ H+    R  FT  + P F + S  + + IC
Sbjct: 331 GVFLDYEAGDVSFYNMRDRSHIYTCPRSAFTVPVRPFFRLGSDDSPIFIC 380


>gi|6453813 butyrophilin, subfamily 2, member A2 isoform a [Homo
           sapiens]
          Length = 523

 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 56/170 (32%), Positives = 86/170 (50%), Gaps = 3/170 (1%)

Query: 459 VILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVEL 518
           V+LD +TAH ++ LSE           Q    +P+RF     VLG   +  G HYWEVE+
Sbjct: 329 VVLDPDTAHPELFLSEDRRSVRRGPYRQRVPDNPERFDSQPCVLGWESFASGKHYWEVEV 388

Query: 519 QKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKA-TRV 577
           +      VG+C  S+ R+G E  L   +  W +E F  +  A  ++ E+ LP  ++  RV
Sbjct: 389 ENVMVWTVGVCRHSVERKG-EVLLIPQNGFWTLEMFGNQYRAL-SSPERILPLKESLCRV 446

Query: 578 GVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSIC 627
           GV L+ + G V F+ + D+ H+    R  FT  + P F + S  + + IC
Sbjct: 447 GVFLDYEAGDVSFYNMRDRSHIYTCPRSAFTVPVRPFFRLGSDDSPIFIC 496


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.131    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,659,394
Number of Sequences: 37866
Number of extensions: 1339494
Number of successful extensions: 8753
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 434
Number of HSP's that attempted gapping in prelim test: 7468
Number of HSP's gapped (non-prelim): 1544
length of query: 630
length of database: 18,247,518
effective HSP length: 108
effective length of query: 522
effective length of database: 14,157,990
effective search space: 7390470780
effective search space used: 7390470780
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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